Suppurative otitis media, unspecified

H8_SUP_OTINAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H66.4
  • Hospital discharge: ICD-9 3824|3829
  • Cause of death: ICD-10 H66.4
  • Cause of death: ICD-9 3824|3829

2 out of 7 registries used, show all original rules.

1049

4. Check minimum number of events

None

1049

5. Include endpoints

None

1049

6. Filter based on genotype QC (FinnGen only)

1006

Control definitions (FinnGen only)

Control exclude
H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H66
Name in latin
Otitis media purulenta chronica non specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14084 6111 7921
Only index persons 11984 5233 6751
Unadjusted period prevalence (%)
Whole population 0.20 0.18 0.22
Only index persons 0.23 0.19 0.26
Median age at first event (years)
Whole population 5.39 6.82 3.92
Only index persons 6.48 9.38 4.23

-FinnGen-

Key figures

All Female Male
Number of individuals 1006 553 453
Unadjusted period prevalence (%) 0.20 0.20 0.21
Median age at first event (years) 34.04 25.20 44.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1049
Matched controls
10484
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
4122
FHL
Tympanostomy (tympanic tube)
119.9
307.7
171
17
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
1031.9
307.7
657
17
UDC00
NOMESCO Finland
Ear microscopy
14.1
302.9
324
323
3829X
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified otitis media
+∞
283.5
259
*
4451
FHL
Guitar cutting
13.8
203.8
206
183
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
783.5
202.4
193
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
463.8
198.1
192
5
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
50.5
194.0
113
25
H66.0
ICD-10 Finland
Acute suppurative otitis media
9.2
186.8
263
368
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
169.4
158
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
283.1
167.7
167
7
H66.9
ICD-10 Finland
Otitis media, unspecified
9.2
163.4
223
298
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
39.7
147.7
91
25
3824A
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified suppurative otitis media
+∞
146.3
137
*
DC1AD
NOMESCO Finland
Temporalbone CT
62.4
125.6
70
12
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
100.6
95
*
H65.2
ICD-10 Finland
Chronic serous otitis media
272.8
98.5
99
*
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
42.9
87.9
53
13
S02CA02
ATC
flumetasone and antiinfectives; otic
7.4
86.8
135
205
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.3
80.2
248
698
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
219.0
79.4
81
*
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
6.6
78.0
135
229
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
72.7
69
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
5.2
72.1
167
371
H60.8
ICD-10 Finland
Other otitis externa
8.7
71.4
94
117
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
38.2
70.9
44
12
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
3.1
70.4
504
2403
DCD00
NOMESCO Finland
Myringoplasty
+∞
68.5
65
*
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
13.0
67.2
66
54
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
66.3
63
*
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
11.1
63.5
69
66
H65.0
ICD-10 Finland
Acute serous otitis media
15.6
62.6
55
37
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
17.4
60.3
50
30
DFF00
NOMESCO Finland
Pure tone audiometry
4.5
59.5
163
413
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
57.8
55
*
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
55.7
53
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
3.5
52.8
221
751
Z97.4
ICD-10 Finland
Presence of external hearing-aid
6.2
52.4
94
164
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
11.8
51.2
53
47
H74.1
ICD-10 Finland
Adhesive middle ear disease
521.9
50.9
50
*
H60.3
ICD-10 Finland
Other infective otitis externa
8.2
49.4
67
86
H04
ICPC
Ear discharge
6.7
45.3
74
117
1450
FHL
Otomicroscopy
16.6
43.6
37
23
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
434.2
42.5
42
*
4742A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Adenoid vegetations
6.5
42.4
71
115
4741B
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PHARYNGICAE]
8.2
42.0
57
73
R4135
NOMESCO Finland
Rehabilitation for hearing problems
9.8
39.1
46
49
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
38.8
37
*
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
15.2
38.3
34
23
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
202.2
38.1
39
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.3
37.4
616
4004
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
6.6
37.1
61
97
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
36.7
35
*
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
36.7
35
*
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
+∞
36.7
35
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
35.6
34
*
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
358.5
35.2
35
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.6
34.9
126
384
DFF15
NOMESCO Finland
Speech audiometry
4.9
34.6
80
175
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
40.7
34.6
43
11
DAX08
NOMESCO Finland
Fitting of hearing aid
4.5
32.6
82
192
TDA90
NOMESCO Finland
Removal wax from ear
10.1
32.2
37
38
4141
FHL
Myringoplasty (also for reasons other than inflammation)
+∞
31.4
30
*
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
4.6
30.9
77
179
H66
ICD-10 Finland
Suppurative and unspecified otitis media
5.1
27.4
59
121
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
27.2
26
*
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
9.4
26.6
32
35
J01DA01
ATC
[U] cefalexin
2.0
26.2
642
4596
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
+∞
26.1
25
*
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
5.9
25.7
47
83
J01DA08
ATC
[U] cefaclor
2.3
24.9
237
1192
J01DA09
ATC
[U] cefadroxil
2.1
23.9
307
1736
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.9
23.6
53
113
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
4.7
23.6
55
121
DEB30
NOMESCO Finland
Radical mastoidectomy
234.8
22.7
23
*
R5120
NOMESCO Finland
Preparation of an aid
5.2
22.5
47
94
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
21.9
21
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
21.6
96
331
DCD10
NOMESCO Finland
Tympanoplasty
+∞
20.9
20
*
R01AD08
ATC
fluticasone; nasal
2.0
20.2
306
1818
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.2
20.2
85
284
DGW00
NOMESCO Finland
Dilatation of eustachian tube
+∞
19.8
19
*
H73.1
ICD-10 Finland
Chronic myringitis
+∞
19.8
19
*
H61.2
ICD-10 Finland
Impacted cerumen
3.2
19.8
81
266
J01CA04
ATC
amoxicillin; systemic
2.3
19.5
910
7734
J01MA02
ATC
ciprofloxacin; systemic
1.9
18.9
359
2289
R01AD09
ATC
mometasone; nasal
1.8
18.8
474
3294
H60.4
ICD-10 Finland
Cholesteatoma of external ear
39.1
18.6
23
6
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
17.8
17
*
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
17.8
17
*
H01
ICPC
Ear pain/earache
2.2
17.7
161
787
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.8
17.4
54
148
H60.1
ICD-10 Finland
Cellulitis of external ear
7.6
17.0
24
32
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
16.7
16
*
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
16.7
16
*
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
+∞
16.7
16
*
4660A
ICD-9 Finland
Acute bronchitis and bronchiolitis, Acute bronchitis
6.8
16.6
26
39
ZXA10
NOMESCO Finland
Bilateral
2.1
16.6
186
985
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
91.5
16.6
18
*
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
91.5
16.6
18
*
J33.0
ICD-10 Finland
Polyp of nasal cavity
4.4
16.5
41
95
4659X
ICD-9 Finland
Acute upper respiratory infections of multiple or unspecified sites, Unspecified site
5.8
16.4
30
53
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.0
16.1
203
1121
J01DB01
ATC
cefalexin; oral
1.9
15.9
846
7156
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
+∞
15.7
15
*
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
+∞
15.7
15
*
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
11.9
15.6
28
24
J01DA06
ATC
[U] cefuroxime
2.1
15.4
152
766
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
15.1
121
560
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
14.6
14
*
H29
ICPC
Ear symptom/complaint other
2.2
14.6
127
608
R01AD05
ATC
budesonide; nasal
2.7
14.6
83
327
H92.0
ICD-10 Finland
Otalgia
2.7
14.5
78
298
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
152.0
14.5
15
*
R03BA05
ATC
fluticasone; inhalant
1.9
14.3
197
1118
R03AC02
ATC
salbutamol; inhalant
1.7
14.2
560
4287
J01FF01
ATC
clindamycin; systemic
1.8
14.0
258
1607
J45.1
ICD-10 Finland
Nonallergic asthma
2.6
13.8
83
336
R03DA04
ATC
theophylline; systemic, rectal
3.0
13.7
62
216
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
13.6
13
*
4151
FHL
Reoperation for chronic otitis media
+∞
13.6
13
*
DEB00
NOMESCO Finland
Cortical mastoidectomy
141.7
13.5
14
*
H02AB07
ATC
prednisone; oral
2.1
13.0
125
622
EMB30
NOMESCO Finland
Adenotomy
3.4
12.7
46
140
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
+∞
12.5
12
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.5
12.3
81
342
J01FA10
ATC
azithromycin; systemic
1.6
12.3
590
4668
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
12.3
182
1054
H60
ICD-10 Finland
Otitis externa
2.7
12.3
67
258
H92.1
ICD-10 Finland
Otorrhoea
47.2
11.9
14
*
R03BC01
ATC
cromoglicic acid; inhalant
4.3
11.8
30
71
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
5.0
11.7
25
51
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.2
11.6
108
530
J01MA12
ATC
levofloxacin; systemic
1.9
11.5
156
877
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
5.8
11.5
21
37
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.2
11.5
45
144
J32.4
ICD-10 Finland
Chronic pansinusitis
5.5
11.4
22
41
R03BA02
ATC
budesonide; inhalant
1.8
11.3
178
1050
H71
ICPC
Acute otitis media/myringitis
4.7
11.0
25
54
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.7
11.0
35
98
H02AB06
ATC
prednisolone; systemic
1.6
10.9
413
3067
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
9.0
10.8
22
25
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.8
10.7
53
194
WX704
NOMESCO Finland
Intubation
2.3
10.7
79
352
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
60.6
10.6
12
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
10.6
134
735
J47
ICD-10 Finland
Bronchiectasis
4.7
10.5
24
52
DCA30
NOMESCO Finland
Exploration of middle ear
+∞
10.4
10
*
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
10.4
10
*
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
10.4
10
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
10.1
83
388
ZXA05
NOMESCO Finland
Left side
1.7
10.0
200
1262
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.8
9.9
30
81
R06AE07
ATC
cetirizine; oral
1.5
9.9
427
3245
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
8.2
9.8
21
26
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
55.5
9.7
11
*
R51.80
ICD-10 Finland
Headache
1.8
9.5
170
1038
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
9.5
200
1279
R03AC12
ATC
salmeterol; inhalant
2.8
9.5
46
167
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
9.5
231
1535
J46
ICD-10 Finland
Status asthmaticus
3.7
9.5
29
79
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.6
9.5
281
1960
4640A
ICD-9 Finland
Acute laryngitis and tracheitis, Acute laryngitis
3.9
9.4
27
70
DCW99
NOMESCO Finland
Other operation on eardrum and middle ear
100.9
9.4
10
*
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
+∞
9.4
9
*
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
9.4
9
*
J01EB05
ATC
sulfafurazole; systemic
8.1
9.4
20
25
J01FA01
ATC
erythromycin; systemic
1.7
9.1
179
1123
N02AX02
ATC
tramadol; systemic, rectal
1.5
8.9
350
2592
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.5
8.9
54
220
DHB20
NOMESCO Finland
Polypectomy of internal nose
4.9
8.9
19
39
R03CC03
ATC
terbutaline; systemic
2.6
8.7
52
210
7803A
ICD-9 Finland
General symptoms, Convulsions
3.9
8.7
25
65
R03AC03
ATC
terbutaline; inhalant
1.8
8.7
126
722
DEE00
NOMESCO Finland
Osseous fixation of hearing aid
50.4
8.7
10
*
R02
ICPC
Shortness of breath/dyspnoea
1.9
8.7
120
678
4630A
ICD-9 Finland
Acute tonsillitis[TONSILLITIS ACUTA]
7.7
8.7
19
25
H70
ICPC
Otitis externa
3.7
8.6
27
75
J01AA02
ATC
doxycycline; systemic
1.5
8.4
645
5443
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.4
8.4
30
91
S02AA30
ATC
antiinfectives, combinations; otic
2.0
8.4
92
481
H70.0
ICD-10 Finland
Acute mastoiditis
+∞
8.3
8
*
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
8.3
8
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
8.2
186
1209
DFX03
NOMESCO Finland
Review, maintenance and user education for hearing aid
14.6
8.2
13
9
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.5
8.2
51
211
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.7
8.1
169
1075
R42
ICD-10 Finland
Dizziness and giddiness
1.6
8.1
187
1222
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
8.1
204
1363
4808X
ICD-9 Finland
Viral pneumonia, Pneumonia due to other virus not elsewhere classified
22.2
8.0
11
5
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
7.9
205
1380
N02BE01
ATC
paracetamol; systemic, rectal
1.6
7.7
846
7604
J35.2
ICD-10 Finland
Hypertrophy of adenoids
2.8
7.7
39
145
H72
ICD-10 Finland
Perforation of tympanic membrane
45.3
7.7
9
*
J01FA09
ATC
clarithromycin; systemic
1.5
7.6
264
1894
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
7.6
167
1076
0601, ,
NOMESCO Finland
80.6
7.4
8
*
H69.0
ICD-10 Finland
Patulous Eustachian tube
13.5
7.4
12
9
3811A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic serous otitis media
+∞
7.3
7
*
38299
ICD-8 Finland
Unspecified otitis media with mastoiditis
+∞
7.3
7
*
DCA40
NOMESCO Finland
Fat patching or other similar technique without opening of tympanic membrane
+∞
7.3
7
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
7.2
50
217
A02BC02
ATC
pantoprazole; systemic
1.4
7.2
564
4717
Z50.1
ICD-10 Finland
Other physical therapy
2.4
7.1
47
200
ZXA00
NOMESCO Finland
Right side
1.6
7.1
203
1394
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
3.9
7.0
20
52
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
3.0
7.0
29
97
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
7.0
52
234
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
6.9
89
491
R05
ICPC
Cough
1.5
6.9
227
1606
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.9
220
1546
A02BC01
ATC
omeprazole; systemic
1.5
6.9
235
1676
H90
ICD-10 Finland
Conductive and sensorineural hearing loss
13.9
6.9
11
8
UDM02
NOMESCO Finland
Sinoscopy
3.3
6.9
25
77
4222
FHL
Endonasal etmoidectomy
8.3
6.8
14
17
4931A
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA SINE EXACERBATIONE]
6.7
6.8
16
24
WX402
NOMESCO Finland
General anaesthesia
1.6
6.8
178
1197
4661A
ICD-9 Finland
Acute bronchitis and bronchiolitis, Acute bronchiolitis
9.4
6.8
13
14
49300
ICD-8 Finland
Asthma, bronchiale
3.7
6.8
21
58
R03BA01
ATC
beclometasone; inhalant
1.7
6.7
114
685
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.6
134
845
J45.8
ICD-10 Finland
Mixed asthma
3.0
6.6
29
100
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.6
348
2701
C01DA14
ATC
isosorbide mononitrate; oral
1.7
6.5
114
690
SPAT1263
SPAT
Sampling
1.4
6.5
412
3300
S01AA01
ATC
chloramphenicol; ophthalmic
2.1
6.5
58
281
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
6.5
232
1670
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.7
6.4
33
124
0602, ,
NOMESCO Finland
70.2
6.4
7
*
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
14.4
6.4
10
7
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
6.4
190
1315
4931B
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA CUM EXACERBATIONE]
11.1
6.3
11
10
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
3.3
6.3
23
71
DDD05
NOMESCO Finland
Plastic repair of ossicular chain
+∞
6.3
6
*
4129
FHL
Other measure in this category
26.8
6.2
8
*
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
7.1
6.2
14
20
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
6.2
71
377
SPAT1301
SPAT
No procedures
1.4
6.2
300
2290
R03CC02
ATC
salbutamol; systemic
1.7
6.1
105
633
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
12.6
6.1
10
8
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
6.1
260
1937
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
6.7
6.0
14
21
TLC02
NOMESCO Finland
Simple extraction of IUD
2.7
6.0
31
117
XFE00
NOMESCO Finland
Epicardial ultrasonography
3.3
6.0
22
68

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
248
909
3.26
52.35
2.7
1.6
—
—
—
0
0
210
1057
2.23
21.78
2.3
1.9
—
—
—
0
0
176
868
2.23
19.00
1.8
1.4
—
—
—
0
0
62
178
3.64
18.64
4.5
4.7
—
—
—
0
0
366
2587
1.64
12.19
3.4
3.1
30.35
30.75
u/l
0.09
348
2454
34
87
4.00
12.06
3.9
2.8
—
—
—
0
0
326
2304
1.60
10.56
3.2
2.5
51.49
58.39
u/l
2.23
306
2148
232
1533
1.66
9.76
3.9
2.8
582.21
554.17
mosm/kgh2o
0.89
200
1316
680
5719
1.54
9.67
7.7
6.9
76.90
77.91
u/l
0.28
648
5354
265
1839
1.59
9.06
4.0
3.7
1.02
1.02
kg/l
0.26
50
279
218
1456
1.63
8.70
1.6
1.7
150532338.13
14509906.31
pmol/l
1.13
188
1213
476
3791
1.47
8.34
5.0
5.7
10.34
12.01
umol/l
3.28
459
3560
112
637
1.85
7.92
4.4
4.5
1.01
0.96
%
0.08
38
219
107
604
1.86
7.75
4.3
4.5
0.06
0.13
%
0.75
34
187
484
3932
1.43
7.30
2.6
2.6
—
—
—
0
0
75
384
2.03
7.24
5.0
3.6
—
—
—
0
0
340
2611
1.45
6.88
4.3
3.4
45.37
56.23
ng/l
0.24
233
1654
264
1931
1.49
6.86
4.0
3.9
14.33
9.98
mg/mmol
0.62
175
1267
237
1700
1.51
6.76
1.6
1.8
0.92
1.14
mg/l
1.10
171
1246
905
8347
1.61
6.51
16.6
12.0
20.66
22.43
mg/l
0.89
734
6470
317
2424
1.44
6.50
3.2
2.8
—
—
—
0
0
437
3541
1.40
6.44
7.9
6.2
1.21
1.21
mmol/l
0.04
385
3010
824
7455
1.49
6.40
18.9
14.4
20.19
14.37
%
0.51
807
7332
501
4159
1.39
6.37
4.4
3.4
0.00
0.00
estimate
0.80
103
879
419
3378
1.40
6.33
3.7
3.2
5.80
5.97
ph
0.34
15
270
553
4679
1.38
6.20
8.6
8.5
4.28
4.06
e9/l
1.57
497
4084
499
4155
1.38
6.16
6.2
4.7
0.00
0.00
estimate
-0.00
92
845
98
579
1.76
6.13
4.1
4.3
0.47
0.56
%
0.26
32
187
90
519
1.80
6.10
1.5
1.2
411.58
197.06
u/ml
0.50
85
472
116
722
1.68
6.02
6.1
4.0
1.68
1.92
mmol/l
0.39
98
583
503
4205
1.38
6.00
4.5
3.4
0.00
0.00
estimate
0.50
84
825
96
572
1.75
5.83
4.7
4.6
0.02
0.07
%
0.77
26
153
661
5791
1.38
5.81
4.3
3.8
11.76
10.57
mm/h
1.47
625
5338
245
1821
1.45
5.75
3.5
3.1
1719.24
1317.51
ng/l
0.67
209
1519
217
1577
1.47
5.72
2.7
2.4
6.08
6.34
e6/l
0.11
191
1414
874
8055
1.51
5.70
17.6
13.5
139.57
139.55
mmol/l
0.07
856
7807
875
8071
1.50
5.63
17.6
13.6
3.96
3.95
mmol/l
0.57
854
7798
534
4539
1.36
5.59
5.3
4.7
6.64
6.50
mmol/l
0.64
488
4136
460
3821
1.36
5.58
7.3
6.3
—
—
—
0
0
392
3178
1.37
5.54
12.8
12.8
1.25
1.22
inr
0.25
147
970
177
1255
1.49
5.25
1.4
1.2
18.96
31.01
iu/ml
1.80
45
366
67
370
1.87
5.24
3.8
2.8
0.28
0.24
e6/l
0.14
67
364
163
1138
1.51
5.21
3.1
2.2
12.59
13.75
umol/l
1.09
154
1059
298
2334
1.39
5.13
3.6
3.0
39.99
87.02
e6/l
0.77
229
1767
476
4030
1.33
4.88
7.1
5.9
27.92
29.22
%
1.75
462
3817
302
2391
1.37
4.82
4.3
3.0
—
—
—
0
0
497
4242
1.32
4.78
6.8
5.8
1.95
2.01
e9/l
0.46
455
3783
249
1919
1.39
4.68
4.8
4.0
—
—
—
0
0
456
3856
1.32
4.64
7.0
5.9
3.01
2.85
%
0.71
439
3631
480
4091
1.32
4.61
6.8
5.8
0.04
0.04
e9/l
0.49
429
3562
493
4221
1.32
4.57
7.1
6.1
0.22
0.19
e9/l
2.27
439
3733
252
1953
1.38
4.56
4.8
3.6
—
—
—
0
0
467
3971
1.32
4.54
6.9
5.7
57.28
56.16
%
1.30
453
3764
382
3159
1.33
4.52
2.6
2.2
73.28
73.93
nmol/l
0.18
357
2863
271
2129
1.37
4.51
3.3
2.9
0.23
0.44
e6/l
1.65
204
1589
478
4082
1.31
4.49
6.9
5.8
0.60
0.57
e9/l
2.82
428
3548
42
209
2.05
4.47
1.0
1.1
1.39
1.85
u/ml
0.31
27
125
457
3881
1.31
4.46
7.3
6.1
8.36
8.32
%
0.10
438
3663
314
2533
1.34
4.38
2.2
2.3
—
—
—
0
0
701
6322
1.33
4.38
4.1
3.9
14.71
14.67
pmol/l
0.16
653
5730
347
2847
1.33
4.29
4.1
3.4
68.38
71.02
e6/l
0.03
245
1902
439
3722
1.31
4.29
7.0
5.9
0.66
0.64
%
0.33
420
3503
224
1725
1.38
4.19
2.8
2.6
13097.19
6421.69
umol/l
0.82
205
1528
58
333
1.78
4.06
7.4
11.1
—
—
—
0
0
144
1034
1.45
3.99
3.3
2.2
2.36
2.37
g/l
0.05
133
953
17
59
2.91
3.91
1.7
1.4
0.46
0.38
g/l
0.22
11
45
17
59
2.91
3.91
1.7
1.4
6.49
6.92
g/l
0.14
11
45
17
59
2.91
3.91
1.7
1.4
2.78
2.89
g/l
0.06
11
44
923
8742
1.46
3.87
15.4
11.3
—
—
—
0
0
160
1179
1.42
3.86
1.4
1.3
12.79
9.74
u/ml
0.23
80
450
365
3057
1.30
3.80
5.3
4.7
35.95
36.20
g/l
0.38
346
2838
87
568
1.58
3.78
4.6
3.3
1.22
1.23
mmol/l
0.52
75
483
645
5812
1.28
3.72
5.1
4.0
—
—
—
0
0
17
61
2.81
3.69
1.7
1.4
—
—
—
0
0
26
118
2.23
3.53
3.7
2.3
—
—
—
0
0
8
13
6.19
3.50
2.0
2.0
—
—
—
0
0
25
113
2.24
3.43
1.5
1.9
0.68
0.74
g/l
0.10
16
91
16
58
2.78
3.43
2.5
2.9
190.08
16.49
mg/l
0.66
11
47
77
501
1.58
3.42
4.5
3.0
153.83
189.58
ng/l
0.45
59
457
44
246
1.82
3.40
1.0
1.2
3.43
2.91
u/ml
0.11
23
148
126
910
1.44
3.40
1.2
1.2
—
—
—
0
0
81
534
1.56
3.40
4.3
2.8
—
—
—
0
0
29
140
2.10
3.39
4.8
2.8
—
—
—
0
0
429
3707
1.26
3.38
10.8
8.7
0.00
0.00
e9/l
0.66
356
3025
257
2081
1.31
3.38
3.0
2.8
—
—
—
0
0
278
2277
1.30
3.36
3.4
3.2
7.58
8.02
mmol/l
0.76
243
1940
106
746
1.47
3.28
5.5
7.6
5.15
5.06
kpa
0.39
100
716
106
747
1.47
3.26
5.5
7.6
11.97
12.83
kpa
0.71
100
721
105
739
1.47
3.25
5.6
7.7
1.47
1.23
mmol/l
0.27
75
581
35
185
1.92
3.22
5.4
2.4
24.13
24.47
mmol/l
0.15
35
179
229
1838
1.31
3.20
3.5
3.3
668.79
231.70
mg/l
0.53
147
1238
78
520
1.54
3.13
5.1
4.3
7.41
7.40
ph
—
7
46
275
2269
1.29
3.12
4.6
3.6
0.00
0.00
estimate
0.69
88
824
911
8671
1.38
3.12
10.5
9.0
26.64
26.06
u/l
0.30
882
8346
38
209
1.85
3.11
1.0
1.1
0.40
1.81
u/ml
1.26
18
105
9
20
4.53
3.11
1.8
4.8
49.61
48.95
%
—
9
20
21
92
2.31
3.11
1.5
1.5
—
—
—
0
0
39
218
1.82
3.04
1.0
1.1
5.27
8.00
u/ml
0.41
18
135
131
974
1.39
3.01
3.4
2.2
22.06
23.58
%
0.54
112
839
21
94
2.26
2.97
4.0
2.6
—
—
—
0
0
790
7402
1.27
2.81
19.3
15.2
333.07
333.51
g/l
0.71
783
7355
49
300
1.66
2.81
2.6
2.7
—
—
—
0
0
208
1679
1.30
2.77
1.3
1.5
18.27
20.25
nmol/l
1.60
188
1433
28
147
1.93
2.67
2.1
2.1
130.43
130.10
g/l
0.03
21
112
230
1898
1.27
2.57
3.6
3.4
—
—
—
0
0
790
7429
1.25
2.57
4.3
3.9
5.93
5.77
mmol/l
2.01
742
6768
607
5560
1.22
2.51
3.2
2.9
41.31
39.99
u/l
0.20
583
5225
798
7528
1.25
2.44
4.9
4.5
1.98
1.85
mu/l
0.98
752
6916
47
297
1.61
2.42
3.0
1.4
16.84
7.29
u/ml
—
5
10
246
2061
1.25
2.41
2.4
2.0
248.28
261.32
u/l
0.07
235
1950
23
118
1.97
2.36
4.6
2.2
—
—
—
0
0
64
437
1.49
2.36
3.5
5.5
—
—
—
0
0
152
1204
1.31
2.33
3.4
2.8
2.55
2.29
e6/l
0.19
81
648
158
1261
1.30
2.30
2.8
2.6
0.75
0.92
e6/l
0.60
87
701
366
3221
1.21
2.22
6.3
5.8
1.21
1.21
mmol/l
0.29
340
2927
725
6805
1.21
2.15
6.2
5.0
39.76
38.75
mmol/mol
1.83
686
6324
72
989
0.71
2.15
1.3
1.3
—
—
—
0
0
27
152
1.80
2.13
1.0
1.1
12.89
6.93
u/ml
0.32
13
72
101
765
1.35
2.12
1.9
2.0
371.39
374.44
nmol/l
0.05
96
701
8
25
3.21
2.09
1.3
2.0
—
—
—
0
0
601
5554
1.19
2.08
5.1
4.2
203.22
1813.04
e6/l
—
9
76
0
56
0.00
2.06
0.0
1.2
—
—
—
0
0
974
9468
1.39
2.06
23.0
17.6
7.15
6.83
e9/l
3.50
958
9205
974
9469
1.39
2.05
22.9
17.5
29.99
30.09
pg
1.01
964
9348
974
9469
1.39
2.05
22.9
17.5
89.87
90.04
fl
0.52
964
9349
118
921
1.32
2.03
8.9
5.5
1.14
1.07
mmol/l
1.63
111
847
974
9471
1.39
2.03
23.0
17.6
4.54
4.54
e12/l
0.22
959
9210
137
1094
1.29
2.00
4.2
3.5
0.83
0.82
mmol/l
0.03
129
1025
974
9475
1.38
1.98
23.2
17.7
135.49
135.71
g/l
0.18
965
9346
15
70
2.16
1.98
2.3
2.2
—
—
—
0
0
26
150
1.75
1.91
1.5
1.6
6412.74
13998.74
e6/l
0.84
19
114
28
166
1.70
1.88
1.0
1.1
12.47
5.39
u/ml
0.44
13
90
972
9462
1.36
1.88
22.9
17.6
39.56
40.73
%
1.42
893
8925
7
22
3.19
1.88
2.7
2.6
—
—
—
0
0
112
879
1.31
1.87
1.9
2.7
4.07
8.24
umol/l
7.66
89
744
323
2852
1.19
1.84
2.0
1.9
96.64
95.20
pmol/l
0.22
183
1534
237
2038
1.21
1.79
2.3
2.2
3.08
2.84
mg/l
0.82
204
1740
971
9461
1.35
1.77
23.1
17.6
254.86
251.43
e9/l
1.01
958
9217
12
54
2.24
1.74
1.8
2.5
604.71
541.37
ml
—
7
35
803
7668
1.20
1.72
4.2
3.7
4.51
4.59
mmol/l
1.61
762
7148
36
234
1.56
1.72
1.4
1.2
350.17
232.59
u/ml
1.29
25
131
28
171
1.65
1.71
2.9
3.3
19.23
27.42
mg/l
1.28
19
109
55
392
1.42
1.69
5.2
4.6
—
—
—
0
0
798
7622
1.19
1.68
4.2
3.7
1.41
1.45
mmol/l
1.84
756
7074
440
4014
1.16
1.65
3.3
2.8
107.40
97.28
ug/l
0.24
417
3729
67
497
1.37
1.65
1.2
1.2
—
—
—
0
0
20
113
1.78
1.61
2.5
1.3
—
—
—
0
0
768
7325
1.18
1.58
3.8
3.4
1.30
1.23
mmol/l
1.55
723
6775
67
502
1.36
1.56
1.7
1.7
1.46
1.40
g/l
0.06
62
460
65
486
1.36
1.54
1.7
1.4
—
—
—
0
0
129
1059
1.25
1.53
1.3
1.3
310.48
533.85
titre
1.67
21
208
5
15
3.34
1.52
2.0
1.0
—
—
—
0
0
5
15
3.34
1.52
2.0
1.0
—
—
—
0
0
5
15
3.34
1.52
2.0
1.0
—
—
—
0
0
7
27
2.60
1.51
1.1
2.5
—
—
—
0
0
7
27
2.60
1.51
2.3
1.6
—
—
—
0
0
13
65
2.01
1.49
1.3
2.4
42.93
36.87
%
0.71
13
65
151
1266
1.22
1.48
1.7
1.7
1158.09
1176.03
nmol/l
0.09
122
946
5
16
3.13
1.44
2.0
1.3
—
—
—
0
0
218
1900
1.19
1.42
1.9
1.4
2.42
2.27
g/l
0.75
141
1170
87
689
1.29
1.40
1.9
1.9
—
—
—
0
0
56
416
1.36
1.40
1.3
1.3
—
—
—
0
0
536
5003
1.14
1.40
3.7
3.4
—
—
—
0
0
88
699
1.28
1.39
1.9
2.0
—
—
—
0
0
88
701
1.28
1.36
2.0
2.0
—
—
—
0
0
808
7771
1.17
1.36
4.5
4.1
2.70
2.74
mmol/l
0.58
764
7200
38
265
1.45
1.35
4.0
4.5
—
—
—
0
0
80
631
1.29
1.34
8.8
7.4
—
—
—
0
0
87
694
1.28
1.33
2.0
2.0
—
—
—
0
0
48
351
1.38
1.33
1.1
1.1
—
—
—
0
0
11
54
2.05
1.33
3.9
3.0
—
—
—
0
0
9
43
2.10
1.30
1.1
1.2
75.30
72.03
%
—
9
38
12
62
1.95
1.28
1.6
1.1
—
—
—
0
0
11
55
2.01
1.27
3.1
6.4
11.15
10.74
%
0.12
11
55
21
130
1.63
1.27
1.1
1.3
—
—
—
0
0
322
2919
1.15
1.27
1.7
1.7
—
—
—
0
0
49
363
1.37
1.26
1.8
1.5
5.52
7.59
u/l
1.74
39
292
80
641
1.27
1.20
1.9
2.1
10.72
12.51
nmol/l
0.91
73
576
6
26
2.31
1.18
1.2
1.2
0.35
14.05
u/ml
—
6
21
62
482
1.30
1.18
2.7
2.6
—
—
—
0
0
13
72
1.81
1.15
1.0
1.2
—
—
—
0
0
12
65
1.85
1.13
1.7
1.5
1.38
1.25
promille
—
7
51
8
40
2.01
1.12
2.5
1.6
0.84
1.19
nmol/l
—
8
30
65
513
1.28
1.12
1.3
1.2
—
—
—
0
0
7
31
2.26
1.10
1.1
1.2
—
—
—
0
0
22
144
1.54
1.09
1.0
1.0
0.42
0.36
u/ml
—
8
54
7
32
2.19
1.08
2.1
1.3
—
—
—
0
0
96
797
1.22
1.08
1.4
1.4
—
—
—
0
0
5
22
2.28
1.03
10.2
15.4
—
—
—
0
0
205
1831
1.15
1.00
1.6
1.6
1.45
1.34
mmol/l
1.04
170
1563
5
23
2.18
0.98
1.0
1.3
5.54
6.01
nmol/l
—
5
23
105
890
1.20
0.97
1.2
1.2
—
—
—
0
0
230
2075
1.14
0.97
4.0
3.7
7.40
7.40
ph
0.15
49
392
238
2153
1.14
0.96
1.4
1.3
1.75
1.49
u/ml
0.15
67
550
24
166
1.46
0.94
5.3
2.1
1.06
0.78
nmol/l
0.68
19
140
24
166
1.46
0.94
1.0
1.2
—
—
—
0
0
15
93
1.62
0.94
1.5
1.7
—
—
—
0
0
18
117
1.55
0.94
1.3
1.6
—
—
—
0
0
34
252
1.36
0.92
1.4
1.3
—
—
—
0
0
149
1309
1.16
0.91
4.3
3.5
359.00
382.34
ng/l
0.05
102
914
259
2363
1.13
0.91
2.9
2.9
2.35
2.35
mmol/l
0.21
244
2094
21
143
1.48
0.90
2.2
2.5
—
—
—
0
0
12
194
0.61
0.90
1.8
2.3
37.42
38.22
g/l
0.26
12
171
75
621
1.22
0.89
13.5
6.7
11.57
8.51
mmol/l
2.28
70
593
6
29
2.07
0.89
1.2
1.3
—
—
—
0
0
14
87
1.62
0.87
1.3
2.5
—
—
—
0
0
14
87
1.62
0.87
1.0
1.0
—
—
—
0
0
8
43
1.87
0.87
1.1
1.2
463.63
319.08
mu/l
—
8
38
54
433
1.26
0.86
1.5
1.3
136.73
266.22
miu/ml
2.65
23
216
48
380
1.28
0.85
1.6
1.5
14.29
14.25
iu/l
0.00
39
310
6
31
1.94
0.84
1.3
1.4
—
—
—
0
0
62
507
1.24
0.84
6.3
3.7
101.23
77.79
ng/l
0.65
52
455
63
517
1.23
0.83
2.4
2.6
4.47
5.85
e9/l
0.79
53
438
29
214
1.36
0.83
3.4
2.9
—
—
—
0
0
81
683
1.20
0.82
2.3
2.4
6845.75
6879.38
u/l
0.00
35
295
30
224
1.35
0.80
8.8
8.9
—
—
—
0
0
44
348
1.28
0.79
2.8
2.3
—
—
—
0
0
20
139
1.45
0.79
2.0
2.0
16.78
16.13
%
0.38
15
62
0
24
0.00
0.79
0.0
2.0
—
—
—
0
0
22
156
1.42
0.79
1.5
1.6
—
—
—
0
0
139
1231
1.15
0.78
3.0
2.6
169.06
124.32
ug/g
0.55
117
975
214
1950
1.12
0.78
2.1
2.2
—
—
—
0
0
13
82
1.59
0.78
2.1
2.3
—
—
—
0
0
13
82
1.59
0.78
1.3
2.3
31.77
33.18
pg
0.30
13
82
6
34
1.77
0.76
1.3
1.6
—
—
—
0
0
0
28
0.00
0.76
0.0
1.4
—
100.82
—
0
20
12
75
1.61
0.75
3.7
2.9
—
—
—
0
0
9
54
1.67
0.74
2.1
1.4
75.44
75.52
umol/l
—
9
54
7
40
1.75
0.71
3.1
2.8
783.29
783.82
u/ml
—
7
40
7
40
1.75
0.71
1.1
1.1
—
—
—
0
0
10
158
0.63
0.71
1.1
1.1
—
—
—
0
0
213
1952
1.11
0.71
6.4
6.5
—
—
—
0
0
77
657
1.18
0.71
2.1
2.0
—
—
—
0
0
305
2851
1.10
0.69
2.1
2.1
—
—
—
0
0
13
85
1.54
0.69
2.2
3.2
—
—
—
0
0
7
43
1.63
0.67
1.1
1.6
—
—
—
0
0
66
560
1.19
0.66
2.0
2.0
—
—
—
0
0
57
477
1.21
0.65
1.4
1.5
—
—
—
0
0
38
306
1.25
0.63
1.5
1.6
—
—
—
0
0
0
20
0.00
0.60
0.0
1.5
—
—
—
0
0
37
454
0.81
0.60
1.4
1.6
—
—
—
0
0
20
148
1.36
0.59
7.2
3.5
2.50
2.27
mmol/l
0.13
13
92
11
72
1.53
0.59
1.1
1.4
—
36.60
—
0
5
10
64
1.57
0.58
3.2
2.6
—
—
—
0
0
10
64
1.57
0.58
6.4
5.1
—
—
—
0
0
32
255
1.26
0.58
1.1
1.1
28.90
5.94
u/ml
—
5
36
7
113
0.62
0.58
1.3
1.2
—
—
—
0
0
6
35
1.72
0.57
1.2
1.2
—
—
—
0
0
8
54
1.48
0.57
2.6
3.0
32404.00
37746.61
ug/l
—
8
54
6
36
1.67
0.56
1.0
1.2
—
—
—
0
0
57
486
1.18
0.56
1.4
1.5
—
—
—
0
0
6
37
1.62
0.55
3.2
3.4
134.67
117.46
nmol/l
—
6
37
98
1096
0.88
0.55
3.1
3.0
0.73
0.75
ug/l
0.15
64
703
43
358
1.21
0.54
1.5
1.3
—
—
—
0
0
58
497
1.18
0.54
1.5
1.6
390.25
269.85
mu/l
1.11
52
438
9
62
1.45
0.53
1.0
1.0
—
—
—
0
0
9
62
1.45
0.53
1.0
1.2
—
—
—
0
0
13
180
0.72
0.51
2.9
2.8
45.77
32.78
umol/l
0.96
13
166
9
64
1.41
0.51
1.1
1.2
—
—
—
0
0
37
306
1.22
0.51
1.2
1.2
—
—
—
0
0
20
153
1.31
0.50
5.1
3.4
5.11
4.10
e9/l
1.67
20
153
55
474
1.17
0.49
1.4
1.5
—
—
—
0
0
7
45
1.56
0.49
2.4
4.6
—
28.42
—
0
9
25
199
1.26
0.48
1.7
1.5
258.36
296.12
ug/g
0.38
14
113
87
779
1.13
0.47
1.6
1.4
—
—
—
0
0
61
533
1.15
0.46
1.9
2.4
10.43
6.30
ug/l
0.63
52
470
51
588
0.86
0.46
1.1
1.3
—
—
—
0
0
59
516
1.15
0.45
2.8
3.5
4.54
4.64
pmol/l
0.31
51
460
13
175
0.74
0.45
1.2
1.1
—
—
—
0
0
53
460
1.16
0.44
1.2
1.1
95.00
156.62
titre
—
5
13
12
86
1.40
0.44
2.1
3.2
—
—
—
0
0
17
130
1.31
0.44
1.4
4.9
—
—
—
0
0
20
157
1.28
0.43
5.3
3.7
64.20
56.48
%
1.98
20
157
21
166
1.27
0.43
2.2
2.5
197.67
67.47
ug/min
0.52
12
102
5
32
1.56
0.42
1.6
1.1
119.60
167.71
mmol/24h
—
5
32
206
1938
1.08
0.42
4.7
4.9
2.14
2.62
ug/l
0.86
185
1726
5
33
1.52
0.41
1.2
1.6
0.02
0.96
u/ml
—
5
33
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
0.88
—
0
9
7
105
0.66
0.39
1.1
1.5
—
—
—
0
0
48
419
1.15
0.39
5.0
4.4
23.69
24.05
mmol/l
0.41
48
412
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
134
1244
1.09
0.38
2.2
2.8
2.44
2.44
mmol/l
0.04
124
1084
11
80
1.38
0.38
1.4
1.4
—
—
—
0
0
5
36
1.39
0.38
1.4
1.4
96.80
88.58
mg/l
—
5
26
9
69
1.31
0.37
1.3
1.3
—
—
—
0
0
5
37
1.35
0.37
1.0
1.0
—
—
—
0
0
9
70
1.29
0.36
1.1
1.0
—
—
—
0
0
16
126
1.27
0.35
1.0
1.2
—
—
—
0
0
6
43
1.40
0.35
1.2
1.0
—
—
—
0
0
6
43
1.40
0.35
1.0
1.3
4.35
5.82
ug/l
—
6
38
16
127
1.26
0.33
1.2
1.6
—
—
—
0
0
14
109
1.29
0.33
1.4
1.9
—
—
—
0
0
79
723
1.10
0.32
2.7
2.2
34.84
32.36
u/l
0.28
70
601
67
736
0.90
0.32
1.3
1.2
—
—
—
0
0
22
183
1.21
0.31
2.5
1.5
—
—
—
0
0
13
101
1.29
0.31
1.1
1.3
—
66.45
—
0
6
184
1936
0.94
0.31
1.7
1.8
—
—
—
0
0
7
54
1.30
0.30
1.6
1.6
5.79
5.66
mmol/l
—
7
54
35
306
1.15
0.30
1.0
1.1
—
—
—
0
0
7
57
1.23
0.29
1.6
1.2
—
—
—
0
0
148
1399
1.07
0.29
1.8
1.5
—
—
—
0
0
8
66
1.21
0.26
3.6
2.8
—
—
—
0
0
8
67
1.19
0.26
1.1
1.1
—
—
—
0
0
20
235
0.85
0.26
1.5
1.9
2.16
5.19
iu/l
—
8
85
9
73
1.23
0.25
1.2
1.2
—
—
—
0
0
14
114
1.23
0.25
1.3
1.4
68.89
68.59
mmol/l
—
9
97
13
105
1.24
0.24
1.7
2.8
27.55
22.26
nmol/l
0.57
13
97
12
148
0.81
0.24
1.4
1.2
—
—
—
0
0
16
133
1.21
0.24
1.1
1.0
2.61
1.75
u/ml
—
8
66
10
78
1.28
0.24
1.0
1.1
—
—
—
0
0
14
115
1.22
0.23
2.7
1.4
—
—
—
0
0
5
39
1.28
0.23
2.8
2.9
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
97.00
209.66
iu/ml
—
5
40
11
135
0.81
0.22
1.5
1.6
—
1680.00
—
0
5
5
42
1.19
0.21
1.4
1.2
0.68
2.52
u/ml
—
5
33
62
575
1.08
0.21
1.6
3.0
74.75
68.76
e9/l
0.77
55
445
0
10
0.00
0.21
0.0
1.2
—
1.83
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
308
2996
1.04
0.21
2.1
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
12
98
1.23
0.21
1.2
1.2
13.47
62.78
u/l
1.18
12
84
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
10
80
1.25
0.20
2.5
1.8
—
—
—
0
0
61
567
1.08
0.20
2.5
3.3
—
—
—
0
0
16
136
1.18
0.20
1.1
1.1
—
—
—
0
0
6
49
1.23
0.20
1.2
1.1
1402.00
1280.90
miu/ml
—
6
49
6
49
1.23
0.20
7.0
3.4
—
—
—
0
0
33
298
1.11
0.19
2.2
3.5
0.76
0.37
g/l
0.82
18
132
126
1310
0.96
0.16
1.7
1.5
—
—
—
0
0
241
2346
1.03
0.16
1.9
1.7
—
—
—
0
0
12
141
0.85
0.16
1.2
1.8
—
—
—
0
0
8
70
1.14
0.16
1.0
1.1
—
—
—
0
0
27
244
1.11
0.16
3.7
2.5
—
—
—
0
0
59
555
1.07
0.15
1.5
1.4
—
—
—
0
0
58
615
0.94
0.15
2.6
4.0
23.72
32.65
ug/l
0.14
43
504
20
178
1.13
0.15
1.6
4.2
1.53
2.12
ratio
—
8
17
9
83
1.08
0.14
1.2
1.3
—
—
—
0
0
7
88
0.79
0.14
1.4
1.8
90.10
90.85
%
—
7
88
94
900
1.05
0.14
1.6
1.4
—
—
—
0
0
11
93
1.18
0.14
4.2
1.8
—
—
—
0
0
20
222
0.90
0.14
3.4
2.4
—
—
—
0
0
24
218
1.10
0.13
2.0
1.3
—
—
—
0
0
10
85
1.18
0.12
1.1
1.3
—
—
—
0
0
17
153
1.11
0.11
4.4
4.0
—
—
—
0
0
279
2835
0.98
0.11
3.3
2.4
—
—
—
0
0
26
279
0.93
0.10
1.3
1.2
—
—
—
0
0
5
47
1.06
0.09
1.4
1.5
0.84
0.99
g/l
—
5
47
5
48
1.04
0.09
2.4
2.7
57.60
50.99
umol/l
—
5
40
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
5
61
0.82
0.08
1.6
1.5
—
—
—
0
0
5
62
0.81
0.08
3.8
3.2
9.70
6.28
nmol/l
—
5
62
14
154
0.91
0.08
1.1
1.1
—
9.80
—
0
13
83
805
1.03
0.08
1.9
3.0
1.75
1.71
%
0.17
75
733
7
64
1.09
0.08
1.3
1.2
—
—
—
0
0
8
74
1.08
0.07
1.5
1.5
34.04
31.16
g/l
—
8
64
8
74
1.08
0.07
1.4
1.5
—
—
—
0
0
9
85
1.06
0.07
1.3
1.4
41.71
55.66
mu/l
—
9
76
9
104
0.86
0.06
1.1
1.1
1.46
1.47
g/l
—
9
91
23
218
1.06
0.05
1.5
2.2
9.54
10.10
g/l
0.26
23
194
25
262
0.95
0.05
1.6
1.1
—
—
—
0
0
113
1111
1.02
0.04
1.9
2.0
—
—
—
0
0
33
342
0.96
0.04
2.9
1.8
—
—
—
0
0
10
109
0.92
0.04
3.0
3.0
0.96
0.91
nmol/l
—
5
84
79
776
1.02
0.03
4.3
3.3
—
—
—
0
0
65
662
0.98
0.03
3.5
3.7
—
—
—
0
0
21
201
1.05
0.03
1.4
1.2
—
—
—
0
0
69
700
0.98
0.02
1.2
1.2
117.58
142.15
iu/ml
0.21
28
269
27
262
1.03
0.02
2.2
2.3
6.02
4.84
umol/l
0.34
21
197
42
418
1.00
0.00
1.5
2.4
—
—
—
0
0
18
182
0.99
0.00
1.4
1.1
—
—
—
0
0
18
180
1.00
0.00
1.4
1.1
—
—
—
0
0
13
126
1.03
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
141.00
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
253.60
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
7.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
8
83
0.96
-0.00
1.3
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
-0.00
1.8
1.7
—
—
—
0
0
5
49
1.02
-0.00
5.4
2.7
35.58
45.85
%
—
5
29
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
9
91
0.99
-0.00
2.3
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_SUP_OTINAS and mortality.

Females

Parameter HR [95% CI] p-value
H8_SUP_OTINAS 1.229 [1.1, 1.37] < 0.001
Birth year 0.995 [0.99, 1.0] 0.263

During the follow-up period (1.1.1998 — 31.12.2019), 641 out of 3842 females with H8_SUP_OTINAS died.

Males

Parameter HR [95% CI] p-value
H8_SUP_OTINAS 1.206 [1.08, 1.35] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 752 out of 4438 males with H8_SUP_OTINAS died.

Mortality risk

Mortality risk for people of age

years, who have H8_SUP_OTINAS.

N-year risk Females Males
1 0.15% 0.237%
5 0.584% 1.523%
10 1.543% 3.554%
15 3.269% 6.65%
20 5.801% 11.043%

Relationships between endpoints

Index endpoint: H8_SUP_OTINAS – Suppurative otitis media, unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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