suppurative otitis media: Inflammation of the middle ear with purulent discharge.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1028 |
4. Check minimum number of eventsNone |
1028 |
5. Include endpointsNone |
1028 |
6. Filter based on genotype QC (FinnGen only) |
1028 |
Control definitions (FinnGen only)
- Control exclude
- H8_MIDDLEMASTOID
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H66
- Name in latin
- Otitis media purulenta chronica non specificata
Similar endpoints
↥List of similar endpoints to
Suppurative otitis media, unspecified
based on the number of shared cases.
Similar with more cases:
- Suppurative and unspecified otitis media
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 14084 | 6111 | 7921 |
| Only index persons | 11984 | 5233 | 6751 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.20 | 0.18 | 0.22 |
| Only index persons | 0.23 | 0.19 | 0.26 |
| Median age at first event (years) | |||
| Whole population | 5.39 | 6.82 | 3.92 |
| Only index persons | 6.48 | 9.38 | 4.23 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1028 | 568 | 460 |
| Unadjusted period prevalence (%) | 0.20 | 0.19 | 0.20 |
| Median age at first event (years) | 31.81 | 22.25 | 43.62 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 912
- Matched controls
- 9118
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
1463.0
323.0
575
11
3829X
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified otitis media
+∞
234.7
215
*
UDC00
NOMESCO Finland
Ear microscopy
17.2
168.5
283
232
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
1953.4
168.1
158
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
284.8
165.3
164
7
H71
ICD-10 Finland
Cholesteatoma of middle ear
1701.2
151.4
143
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
229.6
135.8
137
7
3824A
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified suppurative otitis media
+∞
134.8
126
*
4122
FHL
Tympanostomy (tympanic tube)
110.9
131.4
141
15
H66.0
ICD-10 Finland
Acute suppurative otitis media
11.1
104.6
212
241
4451
FHL
Guitar cutting
11.8
87.4
170
174
H66.9
ICD-10 Finland
Otitis media, unspecified
10.3
86.0
180
212
H65.2
ICD-10 Finland
Chronic serous otitis media
189.4
83.7
86
5
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
80.4
76
*
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
42.0
78.5
98
26
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
192.0
69.1
71
*
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
66.5
63
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
3.5
66.3
445
1943
DCD00
NOMESCO Finland
Myringoplasty
+∞
60.0
57
*
DC1AD
NOMESCO Finland
Temporalbone CT
132.7
58.6
62
5
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
34.4
58.4
76
24
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
57.9
55
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
5.0
57.5
210
519
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
50.5
48
*
S02CA02
ATC
flumetasone and antiinfectives; otic
7.9
50.2
121
174
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
48.3
46
*
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
47.3
45
*
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
6.8
43.5
116
192
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
82.5
42.3
47
6
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
3.9
40.7
189
573
DFF00
NOMESCO Finland
Pure tone audiometry
5.5
40.1
127
261
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
+∞
39.9
38
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
5.2
38.3
128
279
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.5
37.3
528
3261
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
81.4
35.1
39
5
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
+∞
34.6
33
*
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
12.5
34.1
62
53
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
124.7
33.9
36
*
H60.8
ICD-10 Finland
Other otitis externa
9.7
33.9
70
77
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
33.5
32
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
33.5
32
*
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
32.5
31
*
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
32.5
31
*
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
+∞
31.4
30
*
Z97.4
ICD-10 Finland
Presence of external hearing-aid
6.8
29.9
78
124
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
10.1
29.3
59
62
H65.0
ICD-10 Finland
Acute serous otitis media
17.4
28.7
45
27
H60.3
ICD-10 Finland
Other infective otitis externa
10.3
26.8
53
54
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
35.2
26.6
34
10
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
13.8
26.2
45
34
4141
FHL
Myringoplasty (also for reasons other than inflammation)
267.6
25.8
26
*
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
256.6
24.8
25
*
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
8.9
24.6
53
63
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
12.1
24.2
44
38
4741B
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PHARYNGICAE]
9.1
24.1
51
59
H04
ICPC
Ear discharge
6.9
24.0
61
94
J01DA01
ATC
[U] cefalexin; systemic
2.0
23.5
556
3950
DFF15
NOMESCO Finland
Speech audiometry
6.6
22.5
59
95
DEB30
NOMESCO Finland
Radical mastoidectomy
+∞
22.0
21
*
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
+∞
22.0
21
*
J01CA04
ATC
amoxicillin; systemic
2.4
21.2
782
6533
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
20.9
20
*
J01DA08
ATC
[U] cefaclor; oral
2.3
19.8
210
1042
R01AD09
ATC
mometasone; nasal
1.9
19.8
404
2640
1450
FHL
Otomicroscopy
15.0
19.5
32
22
R4135
NOMESCO Finland
Rehabilitation for hearing problems
11.0
19.0
36
34
4742A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Adenoid vegetations
5.2
18.7
59
120
DCD10
NOMESCO Finland
Tympanoplasty
193.6
18.6
19
*
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
16.6
18.4
29
18
J01DA09
ATC
[U] cefadroxil; inhalant, oral
2.1
18.1
263
1495
TDA90
NOMESCO Finland
Removal wax from ear
11.4
17.8
33
30
DGW00
NOMESCO Finland
Dilatation of eustachian tube
+∞
17.8
17
*
R01AD08
ATC
fluticasone; nasal
2.0
17.1
259
1490
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
16.7
16
*
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
+∞
16.7
16
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
5.6
16.4
48
90
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.3
16.3
84
269
DAX08
NOMESCO Finland
Fitting of hearing aid
4.9
15.8
52
111
J01MA02
ATC
ciprofloxacin; systemic
1.9
15.7
307
1934
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
+∞
15.7
15
*
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
+∞
15.7
15
*
H60.4
ICD-10 Finland
Cholesteatoma of external ear
86.5
15.6
17
*
H73.1
ICD-10 Finland
Chronic myringitis
162.5
15.5
16
*
J01DB01
ATC
cefalexin; oral
1.9
15.2
721
6040
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
4.7
14.9
51
114
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
+∞
14.6
14
*
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
14.6
14
*
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
152.2
14.5
15
*
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
13.6
14.3
24
18
R5120
NOMESCO Finland
Preparation of an aid
6.4
14.2
37
60
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.1
14.0
178
946
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
6.0
13.9
38
66
H66
ICD-10 Finland
Suppurative and unspecified otitis media
4.9
13.6
44
93
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
13.6
13
*
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
13.6
13
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.3
13.4
49
118
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
5.0
12.9
41
85
R03AC02
ATC
salbutamol; inhalant
1.7
12.9
449
3329
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
12.5
12.6
22
18
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.2
12.6
68
227
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
12.5
12
*
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
+∞
12.5
12
*
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
+∞
12.5
12
*
DEB00
NOMESCO Finland
Cortical mastoidectomy
131.6
12.5
13
*
ZXA10
NOMESCO Finland
Bilateral
2.0
11.8
160
866
J01FF01
ATC
clindamycin; systemic
1.8
11.7
215
1305
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
12.7
11.7
20
16
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
11.6
98
429
4660A
ICD-9 Finland
Acute bronchitis and bronchiolitis, Acute bronchitis
8.8
11.6
24
28
H91.9
ICD-10 Finland
Hearing loss, unspecified
3.9
11.5
46
121
J01FA10
ATC
azithromycin; systemic
1.6
11.5
512
4014
J01DA06
ATC
[U] cefuroxime; systemic
2.1
11.2
131
668
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
11.2
150
808
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
25.3
11.2
15
6
H61.2
ICD-10 Finland
Impacted cerumen
3.2
11.1
59
195
R01AD05
ATC
budesonide; nasal
2.6
10.7
77
307
H02AB06
ATC
prednisolone; systemic
1.6
10.7
353
2541
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
10.2
10.5
20
20
J45.1
ICD-10 Finland
Nonallergic asthma
2.7
10.5
71
275
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
111.1
10.4
11
*
4808X
ICD-9 Finland
Viral pneumonia, Pneumonia due to other virus not elsewhere classified
+∞
10.4
10
*
DCA30
NOMESCO Finland
Exploration of middle ear
+∞
10.4
10
*
H29
ICPC
Ear symptom/complaint other
2.3
10.4
94
426
EMB30
NOMESCO Finland
Adenotomy
4.1
10.2
39
99
R03BA05
ATC
fluticasone; inhalant
1.9
10.1
165
954
J33.0
ICD-10 Finland
Polyp of nasal cavity
4.7
10.1
33
72
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.6
9.6
71
290
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.1
9.5
113
579
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
4.2
9.5
35
86
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
4.0
9.5
37
96
4151
FHL
Reoperation for chronic otitis media
101.0
9.4
10
*
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
+∞
9.4
9
*
DCW99
NOMESCO Finland
Other operation on eardrum and middle ear
+∞
9.4
9
*
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
9.4
9
*
R03DA04
ATC
theophylline; systemic, rectal
3.0
9.3
51
174
H02AB07
ATC
prednisone; oral
2.1
9.2
108
549
H01
ICPC
Ear pain/earache
2.0
9.2
116
609
R03BA02
ATC
budesonide; inhalant
1.9
9.2
151
878
H69.0
ICD-10 Finland
Patulous Eustachian tube
37.0
9.0
11
*
4659X
ICD-9 Finland
Acute upper respiratory infections of multiple or unspecified sites, Unspecified site
5.0
8.9
27
55
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.1
8.6
94
465
H92.1
ICD-10 Finland
Otorrhoea
27.8
8.5
11
*
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
90.8
8.4
9
*
H70.0
ICD-10 Finland
Acute mastoiditis
+∞
8.3
8
*
J01EB05
ATC
sulfafurazole; systemic
8.6
8.3
17
20
H60.1
ICD-10 Finland
Cellulitis of external ear
5.9
8.3
22
38
H60
ICD-10 Finland
Otitis externa
2.9
8.3
48
169
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
8.2
136
791
N02BE01
ATC
paracetamol; systemic, rectal
1.6
8.2
698
6133
S02AA30
ATC
antiinfectives, combinations; otic
2.2
8.2
84
406
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
5.2
7.9
23
45
R51.80
ICD-10 Finland
Headache
1.8
7.9
135
790
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
6.2
7.9
20
33
4931A
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA SINE EXACERBATIONE]
10.9
7.8
14
13
4630A
ICD-9 Finland
Acute tonsillitis[TONSILLITIS ACUTA]
7.0
7.8
18
26
J01FA01
ATC
erythromycin; systemic
1.7
7.6
156
969
DEE00
NOMESCO Finland
Osseous fixation of hearing aid
80.7
7.4
8
*
ZXA05
NOMESCO Finland
Left side
1.7
7.4
176
1140
R03BC01
ATC
cromoglicic acid; inhalant
3.9
7.3
28
73
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
7.3
7
*
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
7.3
7
*
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
+∞
7.3
7
*
3811A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic serous otitis media
+∞
7.3
7
*
4222
FHL
Endonasal etmoidectomy
9.4
7.3
14
15
S02AA03
ATC
boric acid; otic
9.4
7.3
14
15
4640A
ICD-9 Finland
Acute laryngitis and tracheitis, Acute laryngitis
4.7
7.2
23
50
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
7.2
182
1197
ZXA00
NOMESCO Finland
Right side
1.6
7.1
188
1253
N02AX02
ATC
tramadol; systemic, rectal
1.5
7.1
284
2093
H92.0
ICD-10 Finland
Otalgia
2.5
6.9
53
223
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
4.7
6.9
22
48
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.9
281
2078
J01AA02
ATC
doxycycline; systemic
1.4
6.8
550
4663
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
6.8
206
1421
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.5
6.8
240
1717
H72
ICD-10 Finland
Perforation of tympanic membrane
40.3
6.8
8
*
A02BC01
ATC
omeprazole; systemic
1.6
6.7
197
1348
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
6.7
67
322
H60.0
ICD-10 Finland
Abscess of external ear
7.9
6.6
14
18
H70
ICPC
Otitis externa
3.8
6.6
26
70
4661A
ICD-9 Finland
Acute bronchitis and bronchiolitis, Acute bronchiolitis
12.3
6.6
11
9
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
4.8
6.6
20
42
J35.2
ICD-10 Finland
Hypertrophy of adenoids
3.2
6.5
32
103
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
6.5
160
1044
R03AC03
ATC
terbutaline; inhalant
1.8
6.5
110
645
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.6
6.4
27
77
DDD05
NOMESCO Finland
Plastic repair of ossicular chain
+∞
6.3
6
*
4931B
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA CUM EXACERBATIONE]
26.8
6.2
8
*
7803A
ICD-9 Finland
General symptoms, Convulsions
4.1
6.2
22
54
C09AA05
ATC
ramipril; oral
1.7
6.2
141
900
R03DC03
ATC
montelukast; oral
1.7
6.2
119
724
J47
ICD-10 Finland
Bronchiectasis
4.5
6.2
20
45
J01DC04
ATC
cefaclor; oral
6.3
6.2
15
24
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
6.2
173
1170
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.9
6.1
23
60
Z50.1
ICD-10 Finland
Other physical therapy
2.6
6.1
41
162
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
361
2533
1.65
12.53
3.4
3.1
30.4
30.5
u/l
0.02
343
2402
318
2265
1.58
9.91
3.0
2.5
51.5
56.0
u/l
2.30
297
2107
663
5604
1.51
8.96
7.6
6.9
77.0
77.5
u/l
0.13
632
5241
465
3717
1.46
7.94
4.9
5.7
10.2
11.9
umol/l
3.45
449
3489
255
1804
1.55
7.93
4.0
3.7
1.0
1.0
kg/l
0.12
49
276
211
1435
1.59
7.77
1.6
1.7
156354011.0
14716145.8
pmol/l
1.14
181
1196
67
325
2.13
7.46
3.3
3.0
0.7
0.7
%
0.59
61
312
401
3169
1.43
7.03
4.4
3.5
—
—
—
0
0
260
1894
1.50
6.94
4.2
4.1
12.8
10.3
mg/mmol
0.31
172
1242
231
1670
1.49
6.33
1.6
1.8
0.9
1.2
mg/l
1.16
166
1221
468
3869
1.38
6.06
4.3
4.1
—
—
—
0
0
329
2563
1.42
6.05
4.3
3.4
43.8
56.8
ng/l
0.30
224
1619
41
179
2.34
5.92
1.6
1.9
—
—
—
0
0
128
822
1.64
5.90
5.5
6.1
104.5
104.3
mmol/l
0.19
122
801
112
702
1.67
5.68
5.7
3.9
1.8
1.9
mmol/l
0.26
90
550
785
7112
1.44
5.66
18.6
14.5
13.6
13.4
%
1.49
766
6973
883
8189
1.55
5.65
16.3
12.0
20.8
22.4
mg/l
0.75
715
6348
424
3479
1.37
5.63
7.2
6.1
1.2
1.2
mmol/l
0.19
372
2941
239
1783
1.44
5.51
3.4
3.0
1723.7
1293.0
ng/l
0.71
203
1488
537
4585
1.36
5.48
8.6
8.5
4.3
4.1
e9/l
1.55
481
4003
855
7902
1.49
5.28
17.1
13.4
139.6
139.6
mmol/l
0.06
837
7656
86
513
1.74
5.23
1.5
1.2
378.5
193.9
u/ml
0.40
81
465
856
7917
1.48
5.23
17.1
13.5
4.0
3.9
mmol/l
0.58
835
7645
483
4076
1.35
5.23
4.2
3.4
0.0
0.0
estimate
0.50
84
817
483
4078
1.35
5.20
6.1
4.7
0.0
0.0
estimate
0.00
87
830
645
5692
1.36
5.17
4.3
3.8
11.7
10.5
mm/h
1.33
610
5247
487
4127
1.34
5.08
4.4
3.4
0.0
0.0
estimate
0.50
79
810
65
360
1.86
5.06
3.8
2.8
0.3
0.2
e6/l
0.15
65
354
518
4439
1.34
4.97
5.1
4.6
6.6
6.5
mmol/l
0.70
469
4037
157
1113
1.48
4.67
2.9
2.2
12.7
13.8
umol/l
0.99
148
1028
171
1235
1.46
4.63
1.3
1.3
19.6
30.3
iu/ml
1.45
43
359
207
1558
1.41
4.47
2.5
2.4
6.1
6.4
e6/l
0.09
182
1374
373
3092
1.32
4.33
2.5
2.2
73.5
73.9
nmol/l
0.12
349
2799
685
6196
1.32
4.09
4.1
3.9
14.7
14.7
pmol/l
0.25
637
5613
268
2148
1.33
3.87
1.7
1.6
—
—
—
0
0
261
2094
1.33
3.72
3.1
2.9
0.2
0.4
e6/l
1.69
193
1554
357
2996
1.29
3.66
5.2
4.7
35.9
36.2
g/l
0.48
339
2779
275
2229
1.32
3.64
3.4
3.2
7.5
8.0
mmol/l
1.09
235
1872
138
1009
1.42
3.49
3.0
2.1
2.4
2.4
g/l
0.13
127
929
74
475
1.60
3.48
4.9
4.1
1.2
1.5
mmol/l
0.30
56
343
76
493
1.58
3.42
4.5
3.0
153.8
191.8
ng/l
0.49
59
449
214
1689
1.34
3.39
2.7
2.6
14199.0
6261.8
umol/l
0.95
192
1483
155
1164
1.39
3.37
1.3
1.3
13.2
9.5
u/ml
0.27
77
452
83
557
1.53
3.24
4.1
3.3
1.2
1.2
mmol/l
0.54
71
473
15
56
2.70
3.06
1.9
2.1
—
—
—
0
0
11
34
3.26
3.06
1.0
1.6
—
—
—
0
0
43
248
1.77
3.03
1.0
1.2
2.4
2.0
u/ml
0.10
20
118
102
728
1.44
2.96
5.2
7.4
5.2
5.1
kpa
0.39
96
698
61
390
1.60
2.95
1.9
2.0
—
—
—
0
0
102
729
1.44
2.94
5.2
7.4
12.0
12.9
kpa
0.68
96
703
101
721
1.44
2.93
5.4
7.5
1.6
1.2
mmol/l
0.51
71
559
68
450
1.55
2.85
1.6
1.5
—
—
—
0
0
204
1639
1.30
2.83
1.3
1.5
18.3
20.3
nmol/l
1.61
184
1399
890
8500
1.35
2.72
10.4
8.9
26.9
26.0
u/l
0.54
861
8179
6
10
6.03
2.70
5.5
5.0
—
—
—
0
0
314
2682
1.25
2.63
3.5
3.0
—
—
—
0
0
596
5447
1.22
2.59
3.2
2.9
41.5
39.7
u/l
0.29
572
5116
125
948
1.36
2.58
3.1
2.2
22.2
23.6
%
0.46
107
816
765
7186
1.25
2.53
14.4
10.8
88.4
88.7
ml/min/173m2
0.09
607
5741
150
1173
1.33
2.53
3.3
2.8
2.6
2.3
e6/l
0.21
79
628
27
144
1.90
2.48
1.9
2.1
131.2
129.8
g/l
0.14
20
109
7
17
4.14
2.36
1.3
1.9
—
—
—
0
0
772
7282
1.24
2.33
4.3
3.9
5.9
5.8
mmol/l
2.12
725
6634
18
85
2.14
2.29
1.1
1.4
—
—
—
0
0
263
2236
1.24
2.26
4.4
3.6
0.0
0.0
estimate
0.69
83
811
74
527
1.44
2.22
1.9
1.6
—
—
—
0
0
778
7363
1.23
2.17
5.0
4.5
2.0
1.8
mu/l
1.03
732
6756
14
62
2.27
2.08
1.9
2.1
17.0
10.6
%
—
7
36
153
1234
1.28
2.07
2.8
2.6
0.7
0.9
e6/l
0.56
83
684
710
6678
1.20
2.02
6.2
5.0
39.8
38.7
mmol/mol
1.87
671
6207
14
63
2.24
2.01
1.1
1.6
—
—
—
0
0
101
775
1.34
1.97
1.9
1.8
—
—
—
0
0
115
900
1.31
1.96
7.3
5.3
1.1
1.1
mmol/l
1.38
108
827
140
1125
1.28
1.95
2.0
1.8
—
—
—
0
0
676
6339
1.19
1.95
3.7
3.6
—
—
—
0
0
98
750
1.34
1.95
1.8
2.0
377.9
375.2
nmol/l
0.04
93
691
100
769
1.33
1.92
1.9
1.7
—
—
—
0
0
17
85
2.02
1.91
1.1
2.0
—
—
—
0
0
110
860
1.31
1.89
2.0
2.7
4.0
8.3
umol/l
7.69
88
729
236
2023
1.22
1.86
2.4
2.0
257.6
250.7
u/l
0.03
225
1916
28
168
1.68
1.82
2.9
3.3
19.2
27.8
mg/l
1.38
19
108
12
53
2.28
1.81
1.8
2.5
604.7
541.4
ml
—
7
35
36
231
1.58
1.81
1.3
1.2
—
—
—
0
0
29
176
1.67
1.81
1.7
1.4
—
—
—
0
0
8
29
2.77
1.79
1.0
1.7
—
—
—
0
0
33
208
1.61
1.78
2.7
2.9
—
—
—
0
0
354
3161
1.18
1.78
6.0
5.6
1.2
1.2
mmol/l
0.60
327
2855
26
154
1.71
1.77
1.0
1.1
13.9
7.2
u/ml
0.34
12
76
6
18
3.35
1.75
1.0
1.1
—
—
—
0
0
6
18
3.35
1.75
1.0
1.1
87.5
95.1
%
—
6
18
787
7512
1.20
1.74
4.2
3.7
4.5
4.6
mmol/l
1.65
746
6990
131
1064
1.26
1.70
4.2
3.5
0.8
0.8
mmol/l
0.04
122
990
24
141
1.72
1.69
1.1
1.4
—
—
—
0
0
782
7467
1.20
1.68
4.1
3.7
1.4
1.4
mmol/l
1.97
740
6919
314
2791
1.18
1.65
2.0
1.9
96.9
95.2
pmol/l
0.27
178
1498
952
9288
1.33
1.64
22.8
17.6
135.6
135.7
g/l
0.11
944
9161
5
14
3.58
1.61
1.4
1.3
—
—
—
0
0
54
388
1.41
1.61
1.8
1.6
—
—
—
0
0
6
20
3.01
1.58
2.0
1.6
1.2
1.2
mmol/l
—
6
20
585
5471
1.16
1.58
5.1
4.2
203.2
1808.4
e6/l
—
9
76
752
7172
1.18
1.57
3.8
3.4
1.3
1.2
mmol/l
1.54
707
6633
24
145
1.67
1.55
1.6
1.6
6653.4
14319.7
e6/l
0.80
18
110
25
153
1.65
1.54
1.4
1.5
7.4
6.8
mmol/l
0.28
15
101
8
33
2.43
1.54
1.8
1.1
—
—
—
0
0
19
108
1.77
1.51
2.2
1.4
—
12.7
—
0
16
229
1998
1.19
1.49
2.3
2.2
3.1
2.8
mg/l
0.80
197
1704
148
1239
1.23
1.48
1.7
1.7
1163.5
1170.0
nmol/l
0.03
121
926
34
228
1.51
1.45
1.3
1.2
337.1
235.4
u/ml
0.98
23
127
7
28
2.51
1.45
1.0
1.7
—
—
—
0
0
6
22
2.74
1.43
2.8
3.0
—
—
—
0
0
6
22
2.74
1.43
2.8
3.0
—
—
—
0
0
20
118
1.71
1.42
1.3
1.7
—
—
—
0
0
9
40
2.26
1.40
1.1
1.8
—
—
—
0
0
9
40
2.26
1.40
1.1
1.8
—
—
—
0
0
9
40
2.26
1.40
1.1
1.8
—
—
—
0
0
9
40
2.26
1.40
1.1
1.8
—
—
—
0
0
17
96
1.78
1.39
1.1
1.1
—
—
—
0
0
792
7614
1.17
1.37
4.5
4.1
2.7
2.7
mmol/l
0.66
748
7035
0
37
0.00
1.34
0.0
1.2
—
76.2
—
0
32
9
42
2.15
1.34
1.1
1.2
75.3
72.5
%
—
9
37
427
3946
1.14
1.28
3.2
2.7
107.1
97.1
ug/l
0.23
406
3665
90
727
1.26
1.26
3.5
3.0
—
—
—
0
0
18
107
1.69
1.26
1.1
1.4
—
—
—
0
0
96
782
1.25
1.25
2.6
4.3
246.0
251.0
u/l
0.08
90
744
6
25
2.41
1.24
1.7
1.3
—
—
—
0
0
8
36
2.23
1.24
1.4
3.3
—
—
—
0
0
27
179
1.52
1.24
1.9
1.7
7.7
7.3
mmol/l
—
7
115
10
49
2.05
1.22
1.0
1.6
—
—
—
0
0
16
93
1.73
1.21
1.0
1.4
—
—
—
0
0
6
26
2.31
1.18
1.0
1.1
—
—
—
0
0
8
38
2.11
1.18
1.0
1.2
—
90.4
—
0
5
0
35
0.00
1.15
0.0
1.2
—
14.2
—
0
29
7
30
2.34
1.12
1.1
2.0
—
—
—
0
0
7
30
2.34
1.12
1.1
2.0
—
—
—
0
0
7
31
2.27
1.10
1.1
2.0
—
—
—
0
0
59
461
1.30
1.10
2.2
1.8
—
—
—
0
0
78
633
1.25
1.08
1.9
2.1
10.7
12.6
nmol/l
0.94
69
563
12
67
1.80
1.05
2.4
2.4
1027.8
781.7
e6/l
—
6
31
148
1286
1.18
1.03
4.3
3.5
351.2
360.5
ng/l
0.02
102
894
7
34
2.07
1.03
1.0
1.1
—
—
—
0
0
11
61
1.81
0.98
1.2
1.3
0.1
0.4
u/ml
—
6
24
5
23
2.18
0.98
1.0
1.3
5.5
6.0
nmol/l
—
5
23
10
54
1.86
0.96
1.4
1.2
—
—
—
0
0
0
31
0.00
0.96
0.0
1.0
—
—
—
0
0
67
543
1.25
0.96
1.0
1.1
—
—
—
0
0
7
37
1.90
0.94
2.3
1.4
—
—
—
0
0
200
1793
1.14
0.93
1.6
1.6
1.4
1.3
mmol/l
0.75
166
1531
807
7839
1.14
0.93
16.8
12.7
38.8
40.1
%
3.01
569
6023
17
110
1.55
0.91
2.5
1.3
—
—
—
0
0
8
42
1.91
0.88
1.1
1.2
463.6
321.2
mu/l
—
8
37
47
369
1.29
0.88
1.6
1.5
14.6
13.8
iu/l
0.09
37
300
46
361
1.29
0.87
1.8
1.5
5.6
7.3
u/l
1.36
36
290
253
2317
1.12
0.85
3.0
3.0
2.3
2.4
mmol/l
0.22
237
2038
13
80
1.63
0.84
1.1
1.1
—
—
—
0
0
231
2105
1.13
0.84
1.4
1.3
1.8
1.5
u/ml
0.18
63
536
19
129
1.48
0.83
1.2
1.4
—
—
—
0
0
12
190
0.63
0.83
1.8
2.3
37.4
38.2
g/l
0.26
12
162
23
163
1.42
0.82
3.9
2.1
1.1
0.8
nmol/l
0.63
18
137
6
32
1.88
0.82
1.2
2.1
—
—
—
0
0
39
303
1.30
0.80
1.2
1.2
—
—
—
0
0
72
602
1.21
0.80
10.6
6.5
11.4
8.4
mmol/l
2.17
67
574
25
181
1.39
0.80
1.1
1.5
—
—
—
0
0
66
787
0.83
0.77
4.7
6.4
—
—
—
0
0
40
315
1.28
0.76
7.5
9.1
24.6
24.6
mmol/l
0.04
33
298
15
99
1.52
0.75
2.0
1.4
—
—
—
0
0
15
99
1.52
0.75
2.0
1.5
—
—
—
0
0
5
24
2.09
0.74
1.2
1.2
10.1
8.2
ug/l
—
5
24
11
172
0.64
0.74
1.8
2.4
0.0
0.0
g/l
0.00
11
156
79
673
1.19
0.73
2.3
2.4
7046.2
7165.0
u/l
0.01
34
296
23
168
1.38
0.72
1.2
1.7
—
—
—
0
0
11
170
0.64
0.71
1.8
2.5
0.0
0.0
g/l
0.00
11
155
28
212
1.33
0.70
1.5
1.2
—
—
—
0
0
15
101
1.49
0.70
2.0
1.4
—
—
—
0
0
15
101
1.49
0.70
2.0
1.4
—
—
—
0
0
15
101
1.49
0.70
2.0
1.4
—
—
—
0
0
7
41
1.71
0.70
3.1
2.7
783.3
767.4
u/ml
—
7
41
10
61
1.65
0.68
3.5
3.3
—
—
—
0
0
5
27
1.86
0.68
1.2
1.3
—
—
—
0
0
136
1217
1.14
0.68
3.1
2.6
170.1
124.1
ug/g
0.56
115
964
15
102
1.48
0.67
2.0
1.4
—
—
—
0
0
7
44
1.59
0.65
1.1
1.9
—
—
—
0
0
7
44
1.59
0.65
1.1
1.9
—
—
—
0
0
21
155
1.36
0.63
1.2
1.2
—
—
—
0
0
59
498
1.20
0.63
5.8
3.7
95.5
77.0
ng/l
0.46
49
446
12
79
1.52
0.62
1.0
1.5
—
—
—
0
0
32
253
1.27
0.61
1.1
1.1
28.9
5.9
u/ml
—
5
36
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
71
819
0.86
0.60
1.3
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
67.2
—
0
21
69
594
1.17
0.60
6.1
6.5
1.3
1.3
mmol/l
0.16
64
563
60
511
1.18
0.59
4.0
2.4
68.9
71.5
ml/min/173m2
0.23
31
187
10
64
1.57
0.58
1.1
1.7
—
—
—
0
0
10
64
1.57
0.58
1.1
1.7
—
—
—
0
0
10
64
1.57
0.58
1.1
1.7
—
—
—
0
0
6
35
1.72
0.57
1.2
1.2
—
—
—
0
0
6
35
1.72
0.57
3.2
3.1
134.7
109.8
nmol/l
—
6
35
96
1077
0.88
0.56
3.1
3.1
0.7
0.8
ug/l
0.09
63
696
57
486
1.18
0.56
1.5
1.6
392.9
268.2
mu/l
1.14
51
428
41
340
1.21
0.54
1.8
1.6
—
—
—
0
0
21
160
1.32
0.53
1.1
1.2
—
30.9
—
0
13
9
62
1.46
0.53
1.0
1.2
—
—
—
0
0
207
1927
1.09
0.53
2.1
2.2
—
—
—
0
0
22
170
1.30
0.51
1.0
1.1
—
—
—
0
0
26
206
1.27
0.51
2.3
1.5
—
—
—
0
0
34
279
1.23
0.50
1.6
1.5
48.1
0.2
iu/ml
—
10
57
35
289
1.22
0.49
1.9
1.9
—
—
—
0
0
58
503
1.16
0.48
2.8
3.5
4.5
4.6
pmol/l
0.58
50
450
13
93
1.40
0.48
1.0
1.0
—
—
—
0
0
7
48
1.46
0.47
1.0
1.1
—
—
—
0
0
25
200
1.26
0.46
1.7
1.5
258.4
300.0
ug/g
0.43
14
114
60
524
1.15
0.46
1.8
2.4
10.3
6.3
ug/l
0.60
51
462
16
120
1.34
0.46
1.7
1.3
—
—
—
0
0
45
384
1.18
0.46
1.6
1.4
—
—
—
0
0
32
264
1.22
0.46
2.1
1.7
—
—
—
0
0
18
138
1.31
0.45
1.7
2.0
16.9
16.2
%
0.41
13
62
19
147
1.30
0.45
4.9
3.5
5.0
4.1
e9/l
1.47
19
147
88
791
1.12
0.45
17.5
21.0
1.1
1.3
inr
0.74
12
124
23
183
1.26
0.45
1.1
1.5
—
—
—
0
0
7
50
1.40
0.45
1.0
1.2
—
—
—
0
0
13
174
0.74
0.43
2.9
2.9
47.9
32.8
umol/l
1.30
13
149
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
19
150
1.27
0.40
5.1
3.8
63.3
56.3
%
1.74
19
150
72
646
1.12
0.39
1.4
1.5
—
—
—
0
0
66
589
1.13
0.39
1.3
1.5
—
—
—
0
0
5
35
1.43
0.39
1.0
1.0
—
—
—
0
0
11
80
1.38
0.38
1.0
1.1
101.6
94.8
%
0.37
11
75
20
161
1.25
0.37
2.5
2.6
81.1
69.3
ug/min
0.14
11
99
201
1902
1.07
0.36
4.8
4.9
2.2
2.6
ug/l
0.84
180
1697
9
71
1.27
0.36
1.0
1.4
—
—
—
0
0
78
709
1.11
0.35
2.3
2.2
34.7
32.5
u/l
0.24
68
589
19
233
0.81
0.35
1.5
1.9
2.2
4.8
iu/l
—
8
84
49
433
1.14
0.35
1.5
1.3
106.1
266.2
miu/ml
6.56
20
213
46
405
1.14
0.34
4.9
4.3
24.0
24.1
mmol/l
0.14
39
372
11
82
1.34
0.34
1.2
2.3
33.1
33.2
pg
0.03
11
82
10
133
0.75
0.33
1.4
1.6
—
1680.0
—
0
5
13
100
1.30
0.33
1.0
1.1
—
—
—
0
0
13
100
1.30
0.33
1.0
1.4
—
—
—
0
0
6
46
1.31
0.33
1.5
1.3
—
—
—
0
0
65
588
1.11
0.33
1.4
1.5
—
—
—
0
0
130
1216
1.08
0.33
2.2
2.8
2.4
2.4
mmol/l
0.08
119
1059
13
101
1.29
0.31
1.2
1.2
—
—
—
0
0
13
101
1.29
0.31
1.0
1.1
—
—
—
0
0
7
52
1.35
0.31
1.6
1.6
5.8
5.6
mmol/l
—
7
52
13
164
0.79
0.31
1.6
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
53
1.32
0.31
1.0
1.1
—
—
—
0
0
18
147
1.23
0.30
2.0
1.3
—
—
—
0
0
18
147
1.23
0.30
2.0
1.3
—
—
—
0
0
13
102
1.28
0.30
1.7
2.7
27.5
22.1
nmol/l
0.59
13
95
27
231
1.17
0.30
1.8
1.6
—
—
—
0
0
51
566
0.90
0.29
1.4
1.3
—
—
—
0
0
10
76
1.32
0.28
2.5
1.7
—
—
—
0
0
64
586
1.10
0.27
1.3
1.5
—
—
—
0
0
16
131
1.22
0.27
1.1
1.0
2.6
1.8
u/ml
—
8
66
8
65
1.23
0.27
1.1
1.1
—
—
—
0
0
8
65
1.23
0.27
1.1
1.1
—
—
—
0
0
8
65
1.23
0.27
1.1
1.1
—
—
—
0
0
8
65
1.23
0.27
1.1
1.1
—
—
—
0
0
8
65
1.23
0.27
1.1
1.1
—
—
—
0
0
119
1123
1.07
0.25
1.9
1.7
1.4
1.4
%
0.27
112
1002
20
171
1.17
0.23
1.3
1.4
—
—
—
0
0
11
88
1.25
0.22
2.4
1.6
—
—
—
0
0
7
95
0.73
0.22
3.7
1.6
—
—
—
0
0
131
1247
1.06
0.22
2.2
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
8
102
0.78
0.21
1.1
1.1
1.4
1.5
g/l
—
8
88
0
13
0.00
0.21
0.0
1.4
—
0.4
—
0
8
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
26
230
1.13
0.20
1.2
1.3
—
—
—
0
0
19
219
0.86
0.20
1.5
2.2
3.6
3.2
g/l
0.83
14
171
0
14
0.00
0.20
0.0
1.9
—
2.4
—
0
6
63
589
1.07
0.19
1.3
1.5
—
—
—
0
0
14
119
1.18
0.17
1.0
1.1
—
—
—
0
0
80
759
1.06
0.16
1.5
1.5
—
—
—
0
0
9
78
1.15
0.15
1.0
1.0
—
—
—
0
0
9
78
1.15
0.15
1.0
1.1
—
—
—
0
0
21
234
0.90
0.15
1.1
1.2
—
—
—
0
0
57
603
0.94
0.14
2.6
4.1
24.2
33.3
ug/l
0.14
42
494
200
2050
0.97
0.13
2.4
2.3
—
—
—
0
0
25
273
0.91
0.13
1.3
1.1
—
—
—
0
0
61
579
1.06
0.13
1.5
1.6
—
—
—
0
0
13
114
1.14
0.11
1.1
1.1
—
—
—
0
0
11
95
1.16
0.11
1.2
1.2
13.8
62.9
u/l
1.14
11
83
47
496
0.94
0.11
1.6
1.5
—
—
—
0
0
25
269
0.93
0.10
1.3
1.1
—
—
—
0
0
121
1177
1.03
0.10
1.5
1.6
—
—
—
0
0
5
45
1.11
0.10
1.4
1.3
0.8
1.0
g/l
—
5
45
5
47
1.06
0.09
2.4
2.5
57.6
51.4
umol/l
—
5
38
5
48
1.04
0.09
1.2
1.1
1500.0
1384.2
miu/ml
—
5
48
5
61
0.82
0.08
1.4
1.6
—
—
—
0
0
82
844
0.97
0.08
3.9
4.0
31.4
32.1
%
0.22
68
578
153
1503
1.02
0.07
4.5
4.3
21.6
20.9
%
0.24
79
698
183
1856
0.98
0.06
2.2
2.1
—
—
—
0
0
17
158
1.08
0.06
1.2
1.2
—
—
—
0
0
67
688
0.97
0.06
1.2
1.2
121.9
145.1
iu/ml
0.19
27
264
12
131
0.91
0.05
1.0
1.1
—
—
—
0
0
12
131
0.91
0.05
1.4
1.3
1.6
3.4
u/ml
—
7
45
57
554
1.03
0.05
2.1
1.7
—
—
—
0
0
11
101
1.09
0.04
1.3
1.3
—
—
—
0
0
11
119
0.92
0.04
2.1
2.7
14.4
41.5
u/ml
0.34
11
104
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
190
1.05
0.04
4.1
3.6
0.3
0.4
u/ml
—
10
116
14
149
0.94
0.03
1.1
1.1
—
9.8
—
0
13
27
260
1.04
0.03
1.9
2.8
90.9
93.1
%
0.22
27
246
101
996
1.02
0.03
2.0
1.9
—
—
—
0
0
157
1559
1.01
0.01
1.6
1.5
—
—
—
0
0
27
263
1.03
0.01
2.2
2.2
6.0
5.5
umol/l
0.12
21
197
24
234
1.03
0.00
1.5
2.2
4.0
3.7
g/l
0.45
14
169
24
234
1.03
0.00
1.5
2.2
8.1
7.3
g/l
0.82
14
177
24
234
1.03
0.00
1.5
2.2
—
—
—
0
0
11
111
0.99
0.00
1.0
1.6
—
—
—
0
0
18
175
1.03
0.00
1.6
4.0
1.6
2.1
ratio
—
7
17
30
295
1.02
0.00
1.4
1.4
—
—
—
0
0
18
180
1.00
0.00
1.2
1.2
—
—
—
0
0
29
286
1.01
0.00
1.9
1.5
—
—
—
0
0
37
374
0.99
0.00
1.4
1.6
2.0
3.1
mg/l
1.53
22
253
24
239
1.00
0.00
1.9
1.7
—
—
—
0
0
5
59
0.85
0.00
3.8
2.9
9.7
6.4
nmol/l
—
5
59
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
1.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
0.00
1.5
1.3
—
—
—
0
0
6
67
0.89
0.00
2.8
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
0.00
0.0
2.8
—
5.2
—
0
8
0
5
0.00
0.00
0.0
5.8
—
—
—
0
0
8
83
0.96
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
2.8
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_SUP_OTINAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_SUP_OTINAS | 1.229 [1.1, 1.37] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.263 |
During the follow-up period (1.1.1998 — 31.12.2019), 641 out of 3842 females with H8_SUP_OTINAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_SUP_OTINAS | 1.206 [1.08, 1.35] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 752 out of 4438 males with H8_SUP_OTINAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_SUP_OTINAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.15% | 0.237% |
| 5 | 0.584% | 1.523% |
| 10 | 1.543% | 3.554% |
| 15 | 3.269% | 6.65% |
| 20 | 5.801% | 11.043% |
Relationships between endpoints
↥Index endpoint: H8_SUP_OTINAS – Suppurative otitis media, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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