Arthropathy in ulcerative colitis

ULCER_ARTHR

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

492

4. Check minimum number of events

None

492

5. Include endpoints

None

492

6. Filter based on genotype QC (FinnGen only)

474

Control definitions (FinnGen only)

Control exclude
PSOR_ENTE_ARTHR

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1853 1058 791
Only index persons 1802 1037 765
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.02
Only index persons 0.03 0.04 0.03
Median age at first event (years)
Whole population 45.60 44.83 46.65
Only index persons 45.25 44.58 46.16

-FinnGen-

Key figures

All Female Male
Number of individuals 474 305 169
Unadjusted period prevalence (%) 0.10 0.11 0.08
Median age at first event (years) 46.90 44.99 50.35

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
492
Matched controls
4920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K51.5
ICD-10 Finland
Left sided colitis
151.8
307.7
328
64
A07EC02
ATC
mesalazine; oral, rectal
225.0
307.7
428
142
A07EA02
ATC
hydrocortisone; rectal
91.6
307.7
217
42
A07EC01
ATC
sulfasalazine; oral, rectal
64.0
307.7
345
174
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
187.5
307.7
362
72
A07EA06
ATC
budesonide; oral, local oral
48.7
307.7
227
85
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
343.0
307.7
441
121
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
117.6
307.7
214
32
L04AX01
ATC
azathioprine; systemic
59.5
307.7
260
91
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
4503599627370496.0
307.7
450
*
K51.8
ICD-10 Finland
Other ulcerative colitis
58.3
271.9
159
40
UJF32
NOMESCO Finland
Coloscopy
23.4
259.2
390
691
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
89.1
254.9
136
21
L04AX03
ATC
methotrexate; systemic
18.3
227.0
234
232
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
71.0
222.3
123
23
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
15.6
201.2
228
258
L04AB04
ATC
adalimumab; parenteral
37.5
185.1
120
42
K51
ICD-10 Finland
Ulcerative colitis
60.4
184.6
105
22
UJF30
NOMESCO Finland
Ileoscopy through colon
14.5
184.4
214
248
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
70.3
183.1
101
18
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
16.3
169.7
169
153
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
14.5
154.3
165
166
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
53.4
151.3
88
20
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
137.1
125
*
L01BB02
ATC
mercaptopurine; oral
47.6
134.2
80
20
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
70.1
131.1
72
12
H02AB06
ATC
prednisolone; systemic
16.6
129.8
439
1635
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
12.4
119.9
137
149
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
20.6
115.5
93
55
L01BA01
ATC
methotrexate; systemic
21.8
115.0
90
50
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
19.5
112.5
93
58
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
7.5
110.8
306
889
K50.9
ICD-10 Finland
Crohn disease, unspecified
30.3
110.4
75
29
H02AB07
ATC
prednisone; oral
7.9
102.4
184
345
K50.1
ICD-10 Finland
Crohn disease of large intestine
34.5
101.8
66
22
L04AB06
ATC
golimumab; parenteral
63.1
100.2
56
10
K50.8
ICD-10 Finland
Other Crohn disease
24.0
88.1
65
31
M13.9
ICD-10 Finland
Arthritis, unspecified
8.9
82.1
117
166
J01MA02
ATC
ciprofloxacin; systemic
5.2
71.3
305
1181
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
11.3
70.0
79
82
L88
ICPC
Rheumatoid/seropositive arthritis
11.5
65.3
72
72
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
13.8
63.6
62
51
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
235.8
61.6
62
*
M45
ICD-10 Finland
Ankylosing spondylitis
14.5
61.6
58
45
D94
ICPC
Chronic enteritis/ulcerative colitis
85.7
60.8
67
9
ZX120
NOMESCO Finland
Intravenous
6.5
60.6
117
227
P01BA02
ATC
hydroxychloroquine; oral
6.4
54.1
102
192
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
515.5
48.2
47
*
A07EA01
ATC
prednisolone; oral, rectal
74.0
47.2
53
8
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
106.2
44.7
48
5
L04AD01
ATC
ciclosporin; systemic
13.5
42.3
41
33
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.7
42.1
208
822
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
12.7
41.7
42
36
K50.0
ICD-10 Finland
Crohn disease of small intestine
13.1
41.5
41
34
TPH04
NOMESCO Finland
Cathetrisation of vein
3.8
39.9
170
606
P01AB01
ATC
metronidazole; oral, rectal
3.4
38.1
297
1531
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
10.6
37.9
43
44
H02AB09
ATC
hydrocortisone; systemic
10.6
37.9
43
44
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
14.5
36.9
34
25
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.3
36.4
277
1396
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
34.8
33
*
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
14.2
34.3
32
24
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
182.2
33.1
34
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
10.2
31.9
37
39
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.4
31.7
91
242
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
64.5
31.5
36
6
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.4
31.3
152
578
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
117.7
31.1
33
*
M01AH01
ATC
celecoxib; oral
3.5
30.4
128
444
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
7.7
30.2
44
62
N02AX02
ATC
tramadol; systemic, rectal
2.9
30.0
271
1455
4AA12, ,
NOMESCO Finland
60.7
29.5
34
6
WX002
NOMESCO Finland
Sedation and analgesia
3.4
29.0
134
492
M07.3
ICD-10 Finland
Other psoriatic arthropathies
297.6
28.0
28
*
NH3EA
NOMESCO Finland
Feet X-ray examination with load
11.0
27.4
30
29
A02BC02
ATC
pantoprazole; systemic
3.2
27.1
382
2548
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.0
26.5
86
249
L40.5
ICD-10 Finland
Arthropathic psoriasis
76.7
26.1
29
*
M25.5
ICD-10 Finland
Pain in joint
2.7
25.9
229
1192
UJF92
NOMESCO Finland
Capsular endoscopy
9.4
25.3
31
35
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
21.5
24.7
36
18
L04AA13
ATC
[U] leflunomide
8.7
24.6
32
39
A07DA03
ATC
loperamide; oral
6.6
24.5
41
67
A06AC01
ATC
ispaghula (psylla seeds); oral
2.8
24.5
165
743
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.6
24.3
49
96
L04AC05
ATC
ustekinumab; parenteral
39.8
24.2
30
8
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
39.8
24.2
30
8
UJG02
NOMESCO Finland
Proctoscopy
9.8
23.7
28
30
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
57.0
23.3
27
5
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.3
21.2
58
147
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
218.9
20.7
21
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.4
20.1
83
280
4AB02, ,
NOMESCO Finland
42.0
19.7
24
6
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.7
19.4
47
108
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
8.0
18.9
26
34
L04AB02
ATC
infliximab; parenteral
21.9
18.8
27
13
L04AA01
ATC
[U] ciclosporin
15.9
18.7
30
20
H02AB04
ATC
methylprednisolone; systemic
2.9
18.5
100
394
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
6.0
17.8
32
56
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
19.5
17.5
26
14
1370
FHL
Colonoscopy, whole colon
43.7
17.4
21
5
L04AB01
ATC
etanercept; parenteral
13.9
17.2
29
22
M05BA04
ATC
alendronic acid; oral
4.5
17.1
44
106
C10AC01
ATC
colestyramine; oral
6.1
16.8
30
52
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
16.8
137
662
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
16.7
215
1264
K92.1
ICD-10 Finland
Melaena
5.0
16.6
37
79
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
16.5
221
1319
A02BC01
ATC
omeprazole; systemic
2.4
16.3
155
800
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
16.1
69
237
WVA20
NOMESCO Finland
Medicine administration
6.0
15.6
28
49
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.2
15.5
43
110
K83.0
ICD-10 Finland
Cholangitis
13.7
15.3
26
20
N03AX16
ATC
[U] pregabalin
2.4
15.2
140
711
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.0
15.1
74
275
L40.0
ICD-10 Finland
Psoriasis vulgaris
4.8
14.9
35
78
Z93.2
ICD-10 Finland
Ileostomy status
32.8
14.9
19
6
N02BE01
ATC
paracetamol; systemic, rectal
4.1
14.9
461
3858
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
14.8
80
313
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
6.4
14.8
25
41
N02AJ06
ATC
codeine and paracetamol; systemic
2.1
14.7
243
1554
A07EC03
ATC
olsalazine; oral
154.4
14.5
15
*
253, ,
Kela drug reimbursment
37.3
14.5
18
5
3042, ,
Kela drug reimbursment
37.3
14.5
18
5
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
14.4
66
235
K61.0
ICD-10 Finland
Anal abscess
6.5
13.9
23
37
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
13.7
63
225
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.5
13.7
50
155
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.2
13.7
59
203
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.4
13.6
35
84
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
6.1
13.6
24
41
256, ,
Kela drug reimbursment
77.3
13.6
15
*
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
13.6
13
*
JFH11
NOMESCO Finland
Laparoscopic colectomy
143.8
13.5
14
*
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
5.8
13.5
25
45
JFF10
NOMESCO Finland
Loop enterostomy
26.6
13.5
18
7
JHA00
NOMESCO Finland
Anal or perianal incision
6.5
13.4
22
35
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
12.6
13.2
23
19
L04AA33
ATC
[U] vedolizumab
41.3
13.2
16
*
J01DB01
ATC
cefalexin; oral
2.8
13.1
433
3561
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
23.3
13.0
18
8
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.4
13.0
48
150
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
13.0
194
1182
J01MA12
ATC
levofloxacin; systemic
2.4
12.7
98
456
A02BC05
ATC
esomeprazole; systemic
2.0
12.3
220
1422
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
12.8
12.2
21
17
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
12.8
12.2
21
17
JAH00
NOMESCO Finland
Laparotomy
5.2
12.1
25
50
K60.3
ICD-10 Finland
Anal fistula
5.9
12.0
22
39
ZXE20
NOMESCO Finland
More than three and less than five hours
2.6
12.0
80
347
Z3231
NOMESCO Finland
Registered nurse
2.1
11.9
149
846
D07AC01
ATC
betamethasone; topical
2.0
11.8
186
1145
M01AH02
ATC
rofecoxib; oral
2.7
11.8
69
280
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.7
11.8
68
274
JFH10
NOMESCO Finland
Total colectomy and ileostomy
66.6
11.7
13
*
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
66.6
11.7
13
*
K50
ICD-10 Finland
Crohn disease [regional enteritis]
66.6
11.7
13
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
11.5
179
1095
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
+∞
11.5
11
*
M075, K509,
ICD-10 Finland
+∞
11.5
11
*
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
35.9
11.3
14
*
Z2221
NOMESCO Finland
Medical doctor
2.0
11.2
159
940
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.6
11.2
68
281
M13.0
ICD-10 Finland
Polyarthritis, unspecified
11.5
11.1
20
18
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
11.0
194
1236
K56.7
ICD-10 Finland
Ileus, unspecified
10.9
10.9
20
19
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.4
10.8
40
125
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
61.4
10.7
12
*
R4110
NOMESCO Finland
Physiotherapy
2.0
10.7
147
859
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.7
10.6
35
101
A05AA02
ATC
ursodeoxycholic acid; oral
5.2
10.6
22
44
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
10.5
142
824
B01AB05
ATC
enoxaparin; parenteral
2.0
10.5
158
952
M075, L405,
ICD-10 Finland
+∞
10.5
10
*
H04.10
ICD-10 Finland
Dry eye syndrome
2.5
10.4
74
330
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
10.3
240
1663
M01AX17
ATC
nimesulide; oral
2.1
10.3
113
605
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.9
10.3
52
195
TJF80
NOMESCO Finland
Ostomy education
19.3
10.3
15
8
Z3226
NOMESCO Finland
Physiotherapist
2.2
10.0
99
510
L04AB05
ATC
certolizumab pegol; parenteral
17.1
9.9
15
9
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
12.5
9.9
17
14
L04AG05
ATC
vedolizumab; parenteral
26.6
9.9
13
5
3005
Kela drug reimbursment
Tofacitinib
20.5
9.8
14
7
M01AH05
ATC
etoricoxib; oral
1.9
9.8
335
2604
M01AC06
ATC
meloxicam; systemic, rectal
1.9
9.7
191
1249
R50.9
ICD-10 Finland
Fever, unspecified
2.2
9.7
87
430
D07AD01
ATC
clobetasol; topical
2.2
9.6
91
459
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
101.9
9.4
10
*
TNG10
NOMESCO Finland
Puncture of knee
8.3
9.4
20
25
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
9.4
45
164
M075, K515,
ICD-10 Finland
+∞
9.4
9
*
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
+∞
9.4
9
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
9.4
191
1260
C05AA08
ATC
fluocortolone; rectal, topical
2.3
9.4
77
366
E0000UV, ,
ATC
1.8
9.4
212
1445
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
8.9
9.4
19
22
NG1DA
NOMESCO Finland
X-ray of knees
7.5
9.3
21
29
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
9.2
153
945
WX402
NOMESCO Finland
General anaesthesia
2.0
8.9
116
659
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
8.9
8.9
18
21
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.9
8.9
43
158
A03CA02
ATC
clidinium and psycholeptics; oral
3.5
8.8
31
94
N05CF01
ATC
zopiclone; oral
1.9
8.8
158
1000
3AC01, ,
NOMESCO Finland
14.4
8.7
14
10
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.6
8.6
29
85
K56.0
ICD-10 Finland
Paralytic ileus
11.9
8.6
15
13
A07AA09
ATC
vancomycin; oral
11.9
8.6
15
13
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
8.5
68
319
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
28.1
8.5
11
*
WZA10
NOMESCO Finland
Extensive medical or dental certificate
6.9
8.4
20
30
K51.4
ICD-10 Finland
Inflammatory polyps
91.6
8.4
9
*
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
91.6
8.4
9
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
8.4
104
580
M073, K519,
ICD-10 Finland
+∞
8.4
8
*
XX9XE
NOMESCO Finland
Other ultrasound examination
9.7
8.3
16
17
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
9.7
8.3
16
17
Z3229
NOMESCO Finland
Other healthcare associate professional
2.8
8.3
42
158
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
8.3
78
392
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
14.8
8.2
13
9
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.8
8.2
41
153
WX110
NOMESCO Finland
Infiltration anesthesia
1.9
8.2
366
2999
M03BX02
ATC
tizanidine; oral
1.8
8.2
331
2632
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
12.0
8.1
14
12
L04AA29
ATC
[U] tofacitinib
17.5
8.1
12
7
L20
ICPC
Joint symptom/complaint NOS
3.7
8.1
26
74
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.3
8.1
21
51
R4190
NOMESCO Finland
Nutritional therapy
3.4
8.1
29
89
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
8.0
53
228
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
7.4
8.0
18
25
A07AA02
ATC
nystatin; oral
3.1
8.0
34
116
ZXE00
NOMESCO Finland
One hour or less
1.7
8.0
196
1353
M01CB01
ATC
sodium aurothiomalate; parenteral
11.0
7.8
14
13
SAA02
NOMESCO Finland
Basic examination of mouth
1.8
7.8
353
2878
D01
ICPC
Abdominal pain/cramps general
2.3
7.8
65
310
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
45.7
7.7
9
*
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
3.7
7.7
24
67
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
7.7
277
2118
N06AX11
ATC
mirtazapine; oral
1.7
7.6
175
1181
R05
ICD-10 Finland
Cough
1.9
7.6
107
623
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
3.7
7.5
24
68
M79.1
ICD-10 Finland
Myalgia
2.0
7.5
85
458
R03DC03
ATC
montelukast; oral
2.0
7.5
93
518
Z43.2
ICD-10 Finland
Attention to ileostomy
81.3
7.4
8
*
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
81.3
7.4
8
*
A02BC03
ATC
lansoprazole; oral
1.8
7.4
137
867
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
13.6
7.4
12
9
M07.6
ICD-10 Finland
Other enteropathic arthropathies
+∞
7.3
7
*
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
7.3
7
*
TQW40
NOMESCO Finland
Remowal of suture of skin
2.6
7.2
41
164
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.1
7.2
30
101
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
30.5
7.2
9
*
L04AF03
ATC
upadacitinib; oral
20.4
7.2
10
5
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.9
7.1
34
124
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
7.0
374
3141
D06BX01
ATC
metronidazole; topical
2.2
7.0
63
310
R03AC02
ATC
salbutamol; inhalant
1.7
6.9
283
2210
JF1BD
NOMESCO Finland
Very extensive small bowel CT
14.0
6.9
11
8
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
14.0
6.9
11
8
M54.5
ICD-10 Finland
Low back pain
1.7
6.9
181
1262
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.9
6.9
20
53
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
6.9
189
1333
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
8.4
6.9
14
17
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
11.1
6.8
12
11
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
4.4
6.8
17
40
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
17.0
6.8
10
6
WZC30
NOMESCO Finland
Teaching
2.0
6.8
80
437
G47.3
ICD-10 Finland
Sleep apnoea
1.8
6.7
116
717
J05AB11
ATC
valaciclovir; oral
2.0
6.7
81
446
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.4
6.6
24
74
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
12.5
6.6
11
9
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
6.6
209
1525
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.6
6.6
286
2257
A06AC51
ATC
ispaghula, combinations; oral
3.0
6.5
28
96
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
6.5
207
1512
WX290
NOMESCO Finland
Other blockage of nerve
1.6
6.5
259
2000
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
70.7
6.4
7
*
D05AX02
ATC
calcipotriol; topical
3.7
6.4
20
56
M17.5
ICD-10 Finland
Other secondary gonarthrosis
5.6
6.4
17
31
6960A
ICD-9 Finland
Psoriasis and similar disorders, Psoriatic arthropathy
+∞
6.3
6
*
6410
FHL
Panprococolectomy and ileostomy
+∞
6.3
6
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
6.2
109
675
6419
FHL
Other measure in this category
27.0
6.2
8
*
J02AC01
ATC
fluconazole; systemic
1.6
6.2
211
1560
RD210, ,
NOMESCO Finland
5.5
6.2
17
32
E86
ICD-10 Finland
Volume depletion
6.4
6.2
15
24
L01
ICPC
Neck symptom/complaint
1.9
6.1
84
482
AA1AD
NOMESCO Finland
CT of head and brain
1.8
6.1
113
711
R01AD08
ATC
fluticasone; nasal
1.7
6.1
151
1030
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
6.1
128
836
SPAT1325
SPAT
Vaccination
1.7
6.0
136
905

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
367
550
23.33
278.21
8.0
2.4
186.99
113.49
ug/g
2.88
355
447
299
453
15.28
216.51
2.4
1.3
—
—
—
0
0
401
1497
10.08
112.24
9.5
4.9
36.31
36.54
g/l
0.44
392
1419
438
1895
12.95
102.01
17.9
6.5
—
—
—
0
0
60
14
48.67
101.69
3.0
4.1
48.92
35.60
au/ml
—
9
5
448
2001
14.85
100.52
17.6
6.0
0.58
0.55
e9/l
2.29
434
1768
448
2004
14.82
100.25
17.6
6.0
0.04
0.04
e9/l
3.64
434
1772
451
2069
15.16
97.07
17.6
6.0
2.04
1.94
e9/l
0.68
439
1863
452
2083
15.39
96.69
17.8
6.5
0.20
0.18
e9/l
1.47
439
1860
50
11
50.48
85.56
1.7
2.1
168.09
—
au/ml
—
10
0
458
2318
15.12
83.16
19.1
9.4
4.05
4.02
e9/l
0.14
448
2045
403
1811
7.77
82.71
17.6
6.1
0.72
0.69
%
0.60
398
1708
410
1888
8.03
81.34
18.1
6.4
8.49
8.37
%
0.40
405
1792
379
1630
6.77
81.17
4.0
2.3
73.33
74.46
nmol/l
0.38
370
1498
412
1927
8.00
79.62
16.7
5.8
56.36
56.79
%
0.35
407
1830
406
1877
7.65
79.38
17.7
6.0
2.86
2.79
%
0.21
400
1779
413
1949
7.97
78.58
17.8
6.1
29.58
28.75
%
0.91
408
1857
257
879
5.03
70.08
4.1
2.1
2.92
2.98
mg/l
0.15
233
757
197
582
4.98
63.56
1.7
1.3
720.00
503.23
titre
0.66
64
124
364
1775
5.04
59.36
19.4
8.6
0.00
0.00
e9/l
0.43
343
1458
472
2950
15.76
55.03
10.8
3.9
12.22
10.14
mm/h
3.59
463
2748
123
284
5.44
52.32
6.1
4.8
0.03
0.20
%
0.73
34
79
102
199
6.20
52.09
1.1
1.1
—
—
—
0
0
123
293
5.26
50.34
5.7
4.6
0.22
0.64
%
2.18
37
96
124
298
5.23
50.22
6.4
4.8
0.00
0.14
%
2.89
35
93
127
322
4.97
48.11
6.3
4.7
0.29
0.94
%
3.89
38
118
160
532
3.97
41.85
1.4
1.5
—
—
—
0
0
55
72
8.47
40.32
6.3
3.9
3.79
4.57
e9/l
1.49
55
72
55
73
8.36
39.85
6.4
4.5
55.55
57.81
%
0.52
55
73
226
989
3.38
38.12
12.2
6.7
—
—
—
0
0
189
743
3.51
37.89
1.4
1.3
9.55
10.37
u/ml
0.05
64
310
95
234
4.79
36.68
1.6
1.2
—
—
—
0
0
158
568
3.62
36.20
2.7
2.3
12.87
14.40
umol/l
1.54
153
531
141
479
3.72
35.08
2.6
2.3
21.18
24.43
%
1.85
125
419
337
1944
3.33
34.40
6.2
4.5
0.00
0.00
estimate
-0.00
91
365
337
1946
3.32
34.29
4.8
3.2
0.00
0.00
estimate
0.50
95
380
338
1965
3.30
33.80
4.8
3.2
0.02
0.01
estimate
0.25
88
353
182
752
3.25
32.90
1.4
1.3
21.23
30.30
iu/ml
0.89
55
259
61
114
5.97
32.03
1.4
1.2
81.67
65.56
titre
—
6
9
323
1877
3.10
31.37
4.4
2.8
92.73
95.91
ug/l
0.15
311
1765
403
2674
3.80
31.00
6.2
3.9
—
—
—
0
0
171
719
3.11
29.52
1.5
1.6
—
—
—
0
0
302
1757
2.86
28.07
5.9
7.0
1.21
1.22
mmol/l
0.23
261
1520
282
1594
2.80
27.53
4.1
3.0
5.79
5.82
ph
0.06
21
158
40
59
7.29
26.28
1.8
1.4
—
—
—
0
0
322
1999
2.77
25.33
6.7
6.3
9.56
10.59
umol/l
1.52
311
1903
182
855
2.79
24.97
4.2
3.2
—
—
—
0
0
240
1296
2.66
24.94
3.9
3.3
53.03
86.15
e6/l
0.41
175
902
206
1040
2.69
24.42
3.5
3.9
7.40
7.40
ph
0.32
39
193
95
311
3.55
24.32
2.6
2.5
11.78
10.40
g/l
2.83
90
287
31
38
8.64
23.75
2.2
1.3
42.10
48.50
%
0.31
24
30
270
1579
2.57
23.30
5.3
6.3
1.21
1.22
mmol/l
0.43
258
1454
81
246
3.74
23.15
1.7
1.7
1.35
1.44
g/l
0.18
76
228
242
1382
2.48
21.45
2.1
1.9
93.21
98.39
pmol/l
0.98
152
729
41
78
5.64
20.97
1.9
1.5
8053.94
15306.36
e6/l
0.49
33
58
217
1201
2.44
20.34
4.1
2.6
62.70
59.82
u/l
0.22
206
1129
244
1423
2.42
20.34
4.8
3.4
30.71
30.77
u/l
0.01
228
1358
95
346
3.16
20.28
2.7
2.5
0.23
0.23
g/l
0.16
86
330
256
1542
2.38
19.61
10.6
9.5
1.10
1.14
inr
0.61
102
472
199
1085
2.40
19.00
3.2
2.8
281.89
119.60
e6/l
0.37
171
830
90
336
3.05
18.31
1.3
1.4
—
—
—
0
0
183
982
2.37
17.91
3.3
2.7
0.31
0.42
e6/l
0.50
154
738
127
583
2.59
17.39
2.5
2.4
0.98
0.90
e6/l
0.19
92
325
186
1023
2.32
17.03
5.6
3.4
0.00
0.01
estimate
0.50
89
354
168
892
2.34
16.63
5.1
3.9
—
—
—
0
0
42
103
4.36
15.95
3.8
2.6
—
—
—
0
0
166
897
2.28
15.60
1.6
1.8
—
—
—
0
0
44
115
4.10
15.38
1.2
1.2
14.90
15.52
u/ml
—
5
20
258
1674
2.14
15.19
2.4
2.0
—
—
—
0
0
95
410
2.63
14.55
9.0
7.6
104.60
104.15
mmol/l
0.60
95
410
36
84
4.55
14.54
1.0
1.1
—
—
—
0
0
146
770
2.27
14.37
1.7
1.5
20.07
21.25
nmol/l
0.46
136
670
24
39
6.42
14.33
1.3
1.2
—
—
—
0
0
305
2149
2.10
13.98
5.5
4.8
6.61
6.57
mmol/l
0.11
289
1998
140
734
2.27
13.92
2.8
2.3
5.49
6.63
e6/l
0.38
131
663
138
721
2.27
13.82
2.5
1.6
417.17
27636222.26
pmol/l
1.00
125
626
26
49
5.55
13.38
1.8
1.3
—
—
—
0
0
169
971
2.13
13.27
3.2
2.6
—
—
—
0
0
170
986
2.11
12.97
2.7
2.5
2207.84
6316.72
umol/l
1.01
159
874
45
138
3.49
12.51
2.2
1.4
0.21
0.24
g/l
1.38
45
133
81
350
2.57
12.27
2.4
2.3
56.18
170.79
u/l
0.39
74
296
166
971
2.07
12.26
4.9
3.4
95.81
95.13
%
0.14
158
943
131
703
2.18
12.10
3.0
2.6
553.04
550.08
mosm/kgh2o
0.05
116
607
46
147
3.35
11.99
2.2
1.3
1.16
1.19
g/l
0.26
46
141
43
132
3.47
11.93
1.4
1.2
—
—
—
0
0
473
4155
4.58
11.45
20.9
13.1
3.90
3.95
mmol/l
4.09
465
4038
80
357
2.48
11.29
2.8
3.0
1.88
1.80
%
0.25
73
322
75
325
2.54
11.26
5.2
3.3
—
—
—
0
0
471
4137
4.25
11.16
21.1
13.0
139.33
139.71
mmol/l
3.75
465
4027
83
379
2.43
11.14
2.7
2.1
303.95
362.46
nmol/l
2.12
77
353
105
533
2.23
11.04
1.8
2.1
—
—
—
0
0
69
290
2.60
11.02
2.6
3.6
2.66
1.88
mmol/l
1.07
57
241
107
550
2.21
10.90
2.7
2.6
2.56
3.27
e6/l
0.35
72
292
107
558
2.17
10.48
2.0
1.7
1249.16
1223.13
nmol/l
0.09
76
432
22
27
8.48
10.42
2.0
1.4
41.81
42.65
%
0.03
14
20
44
151
3.10
10.21
1.2
1.3
—
—
—
0
0
61
251
2.63
10.15
1.9
3.1
83.33
73.45
e9/l
0.86
46
192
30
81
3.88
10.02
1.3
1.3
307.07
257.57
u/ml
0.32
14
45
150
905
1.95
9.80
1.8
1.7
1.04
1.07
mg/l
0.06
121
686
178
1141
1.88
9.65
4.4
2.9
—
—
—
0
0
169
1068
1.89
9.56
2.0
2.1
113.93
270.49
u/l
1.78
164
1017
197
1307
1.85
9.55
4.1
3.1
23.09
27.40
ng/l
0.37
113
779
98
517
2.12
9.24
1.3
1.2
—
—
—
0
0
64
286
2.42
8.95
3.0
2.9
4.38
6.24
e9/l
0.71
54
248
20
28
7.40
8.82
1.5
1.3
413.75
74.00
titre
—
8
5
143
879
1.88
8.68
1.8
1.4
2.70
2.24
g/l
2.59
107
566
23
57
4.18
8.61
1.0
1.1
—
—
—
0
0
63
286
2.38
8.50
4.2
3.3
—
—
—
0
0
85
445
2.10
8.12
3.3
2.9
5.50
6.52
umol/l
0.24
80
386
42
162
2.74
7.92
2.1
1.6
—
—
—
0
0
18
28
6.63
7.47
1.3
1.4
6802.64
2155.61
e6/l
0.48
11
18
68
340
2.16
7.29
3.1
4.5
4.48
19.41
ug/l
0.61
48
275
245
1847
1.65
6.88
2.9
2.5
—
—
—
0
0
56
268
2.23
6.68
7.4
9.5
—
—
—
0
0
23
69
3.45
6.63
1.0
1.1
—
—
—
0
0
35
136
2.69
6.52
1.6
2.3
1.60
1.42
g/l
0.61
28
115
131
866
1.70
5.94
5.2
3.3
1.02
1.02
kg/l
0.60
13
112
39
168
2.44
5.91
4.2
3.2
—
—
—
0
0
17
45
3.88
5.86
1.4
1.2
—
—
—
0
0
53
270
2.08
5.41
2.6
3.7
1.23
1.23
mmol/l
0.01
46
238
41
189
2.28
5.36
2.5
2.8
0.94
0.09
e6/l
0.57
41
181
169
1219
1.59
5.34
2.6
3.2
2.32
2.35
mmol/l
2.82
162
1098
470
4368
2.70
5.29
23.1
11.1
—
—
—
0
0
32
133
2.50
5.25
4.3
4.8
—
—
—
0
0
19
59
3.31
5.22
1.2
1.0
1.56
1.44
g/l
0.69
14
53
43
205
2.20
5.19
3.8
7.3
—
—
—
0
0
142
989
1.61
5.16
1.3
1.3
0.76
1.75
u/ml
1.31
36
288
82
493
1.80
5.14
1.6
1.4
—
—
—
0
0
20
65
3.16
5.12
1.3
1.2
—
—
—
0
0
41
193
2.23
5.11
7.4
7.6
25.87
24.94
mmol/l
0.89
41
193
76
450
1.81
5.00
4.2
6.0
1.02
1.02
mmol/l
0.05
70
424
93
586
1.72
4.95
2.5
3.5
0.79
0.83
mmol/l
2.99
87
556
12
21
5.83
4.78
1.5
1.5
—
—
—
0
0
23
85
2.79
4.74
1.2
1.4
—
—
—
0
0
423
3816
1.77
4.69
5.0
4.7
1.74
2.13
mu/l
0.68
399
3560
163
1197
1.54
4.64
2.6
2.2
—
—
—
0
0
7
5
14.17
4.59
2.4
1.0
45.00
33.00
%
—
7
5
91
589
1.67
4.37
2.6
2.7
2.43
2.43
mmol/l
0.20
83
518
41
206
2.08
4.36
1.9
2.4
—
—
—
0
0
63
368
1.82
4.33
7.4
9.9
1.24
1.18
mmol/l
0.05
45
293
10
16
6.35
4.31
2.8
2.6
—
—
—
0
0
21
79
2.73
4.21
1.9
1.9
137.31
130.45
g/l
0.72
16
60
28
124
2.33
4.04
2.5
2.0
0.30
1.27
ug/l
1.56
28
113
13
31
4.28
4.04
1.5
1.4
—
—
—
0
0
22
87
2.60
4.02
3.0
1.8
—
—
—
0
0
7
7
10.12
4.02
2.1
1.9
—
—
—
0
0
363
3202
1.51
3.89
4.5
4.1
14.68
14.45
pmol/l
1.02
340
2956
341
2974
1.48
3.84
4.3
3.2
53.20
43.83
u/l
1.57
329
2831
10
20
5.08
3.70
1.4
1.5
32.10
30.05
umol/l
—
10
20
54
321
1.77
3.52
8.4
10.5
121.37
122.04
g/l
0.10
54
312
6
6
10.10
3.50
1.0
1.3
—
—
—
0
0
54
332
1.70
3.14
8.5
10.4
96.72
96.08
%
0.63
54
320
137
1042
1.44
3.11
3.2
2.5
—
—
—
0
0
50
302
1.73
3.10
1.4
1.4
—
—
—
0
0
10
26
3.90
2.99
1.0
1.0
—
—
—
0
0
67
443
1.59
2.95
2.1
1.6
—
—
—
0
0
132
1007
1.42
2.93
2.9
3.3
—
—
—
0
0
39
225
1.80
2.84
1.1
1.1
—
106.00
—
0
5
39
225
1.80
2.84
3.7
2.2
—
—
—
0
0
16
65
2.51
2.81
2.4
1.4
—
—
—
0
0
9
23
3.97
2.78
1.0
1.0
—
—
—
0
0
8
19
4.26
2.69
1.5
1.5
—
—
—
0
0
399
3679
1.45
2.64
5.7
5.1
38.22
39.19
mmol/mol
1.23
386
3477
16
68
2.40
2.58
1.3
1.4
—
—
—
0
0
308
2730
1.34
2.55
3.8
3.3
—
—
—
0
0
23
116
2.03
2.50
1.2
1.1
—
—
—
0
0
8
21
3.85
2.47
1.3
1.2
—
—
—
0
0
10
32
3.17
2.45
5.0
2.5
—
—
—
0
0
23
117
2.01
2.44
1.7
1.4
276.33
303.29
ug/g
0.26
17
67
28
153
1.88
2.43
1.1
1.1
—
—
—
0
0
36
213
1.74
2.43
6.5
9.6
23.91
24.69
mmol/l
0.72
36
200
11
40
2.79
2.28
3.0
3.9
—
—
—
0
0
14
60
2.37
2.23
2.4
2.2
—
—
—
0
0
9
29
3.14
2.23
1.6
1.4
66.67
73.14
umol/l
—
9
29
76
552
1.45
2.18
1.6
1.5
—
—
—
0
0
71
511
1.46
2.14
1.2
1.2
—
—
—
0
0
16
75
2.17
2.10
1.1
1.1
—
—
—
0
0
85
636
1.41
2.08
3.7
3.5
79.96
314.72
ng/l
1.13
52
425
33
202
1.68
2.01
2.3
2.1
2310.17
2526.92
u/l
—
6
79
8
27
2.99
1.94
1.1
1.1
—
—
—
0
0
20
106
1.92
1.93
1.0
1.2
—
—
—
0
0
7
22
3.21
1.88
1.6
1.5
115.71
163.06
nmol/l
—
7
22
14
66
2.15
1.83
1.6
4.5
—
—
—
0
0
15
73
2.09
1.82
2.4
2.5
—
—
—
0
0
11
47
2.37
1.79
1.2
1.4
—
—
—
0
0
8
30
2.69
1.73
1.4
2.4
13.74
25.61
ug/l
—
8
30
8
30
2.69
1.73
1.8
1.6
0.87
1.09
g/l
—
8
30
7
24
2.94
1.73
1.0
1.0
—
—
—
0
0
27
164
1.68
1.72
2.1
2.6
0.67
0.64
%
0.16
27
164
22
126
1.78
1.71
3.5
9.7
0.98
0.91
%
0.39
22
117
8
31
2.61
1.66
1.9
1.8
52.29
37.89
%
—
8
31
7
25
2.83
1.65
5.6
7.6
—
—
—
0
0
10
41
2.47
1.65
1.6
1.5
—
—
—
0
0
22
129
1.74
1.59
3.5
9.5
1.70
1.71
%
0.02
22
119
6
20
3.02
1.58
1.0
1.1
1997.83
1633.90
miu/ml
—
6
20
48
341
1.45
1.58
1.1
1.2
—
—
—
0
0
393
3705
1.30
1.56
36.5
15.1
331.09
332.92
g/l
3.97
393
3681
5
15
3.36
1.52
1.6
1.3
76.00
71.40
nmol/24h
—
5
15
27
170
1.62
1.52
2.1
2.6
1.06
1.32
%
0.88
27
170
21
340
0.60
1.50
1.2
1.4
—
—
—
0
0
34
229
1.52
1.46
2.8
3.6
7.43
7.41
ph
—
8
34
5
16
3.15
1.44
1.2
1.4
—
—
—
0
0
6
22
2.75
1.44
1.7
1.2
—
—
—
0
0
7
29
2.43
1.39
1.6
1.3
—
—
—
0
0
13
67
1.97
1.39
2.5
2.8
4.72
4.97
kpa
0.69
13
67
13
67
1.97
1.39
2.5
2.8
3.16
2.56
mmol/l
—
7
42
13
67
1.97
1.39
2.5
2.8
8.78
9.11
kpa
0.39
13
67
5
17
2.96
1.36
1.0
1.2
—
—
—
0
0
16
90
1.80
1.34
5.9
4.3
—
—
—
0
0
125
1053
1.25
1.34
1.8
1.7
1.32
1.44
mmol/l
1.26
108
900
6
24
2.52
1.30
6.2
2.6
—
—
—
0
0
5
18
2.80
1.29
1.0
1.1
—
—
—
0
0
17
99
1.74
1.28
1.5
1.8
39.80
38.88
g/l
0.34
17
92
38
270
1.44
1.28
1.2
1.4
—
—
—
0
0
8
36
2.24
1.24
3.0
3.5
2.25
2.77
nmol/l
—
8
36
6
25
2.42
1.24
1.2
1.2
231.40
152.84
iu/ml
—
6
25
46
610
0.73
1.24
1.3
1.3
—
—
—
0
0
10
49
2.06
1.22
1.0
1.1
—
—
—
0
0
5
19
2.65
1.22
1.0
1.1
—
—
—
0
0
5
19
2.65
1.22
1.2
1.4
—
—
—
0
0
11
57
1.95
1.18
1.4
1.7
—
—
—
0
0
15
87
1.75
1.16
1.1
1.1
—
—
—
0
0
15
87
1.75
1.16
1.1
1.1
—
—
—
0
0
0
35
0.00
1.15
0.0
11.0
—
0.62
—
0
35
19
120
1.61
1.10
1.8
1.8
2.46
4.73
iu/l
1.62
11
46
7
33
2.14
1.06
1.3
1.1
46.06
30.61
mg/l
—
7
26
43
325
1.35
1.05
2.6
4.4
—
—
—
0
0
134
1168
1.20
1.03
1.5
1.5
—
—
—
0
0
9
47
1.93
1.02
2.8
3.6
—
—
—
0
0
5
108
0.46
1.02
1.0
1.2
—
—
—
0
0
5
23
2.19
0.98
1.2
2.3
1940.00
2161.96
ml
—
5
23
5
23
2.19
0.98
5.4
3.1
430.20
737.70
u/ml
—
5
23
7
36
1.96
0.97
1.1
1.9
—
—
—
0
0
17
109
1.58
0.94
1.1
1.3
455.24
422.45
mg/l
0.19
17
102
154
1719
0.85
0.93
2.8
2.6
—
—
—
0
0
65
532
1.26
0.91
2.4
2.1
29.46
29.49
s
0.02
59
520
8
42
1.92
0.89
2.6
3.0
—
—
—
0
0
6
31
1.95
0.84
1.2
1.2
—
—
—
0
0
37
287
1.31
0.80
1.9
2.2
12.63
13.16
nmol/l
0.17
31
268
11
66
1.68
0.79
1.3
1.2
2.35
2.88
ug/l
0.31
11
55
24
176
1.38
0.74
14.3
13.2
—
—
—
0
0
5
25
2.01
0.73
1.2
1.2
10168.20
1387.29
e6/l
—
5
14
18
126
1.44
0.71
1.8
4.1
0.19
0.19
g/l
—
8
58
7
41
1.72
0.70
1.0
1.1
—
—
—
0
0
13
85
1.54
0.69
1.1
1.2
—
—
—
0
0
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
7
44
1.60
0.65
1.3
1.1
—
—
—
0
0
119
1069
1.15
0.64
3.8
3.8
3.06
10.79
mg/mmol
4.68
88
682
5
30
1.67
0.61
1.6
1.2
175.58
181.37
pmol/l
—
5
30
0
22
0.00
0.59
0.0
5.4
—
—
—
0
0
12
81
1.49
0.57
2.4
1.7
5.66
5.21
mmol/24h
0.22
12
69
48
564
0.83
0.54
2.9
2.6
0.67
0.70
ug/l
0.10
32
339
59
509
1.18
0.54
1.7
1.7
—
—
—
0
0
6
40
1.51
0.51
1.2
1.9
34.00
33.63
pg
—
6
40
10
67
1.50
0.50
1.4
1.3
9.40
4.70
u/ml
—
5
27
10
67
1.50
0.50
1.9
2.9
—
—
—
0
0
7
45
1.56
0.49
2.3
2.7
4.23
4.03
mmol/l
—
7
45
7
45
1.56
0.49
2.3
2.7
—
—
—
0
0
7
45
1.56
0.49
2.3
2.7
105.57
105.98
mmol/l
—
7
45
11
76
1.46
0.48
5.1
13.3
105.82
105.33
mmol/l
0.09
11
67
11
76
1.46
0.48
5.1
13.3
11.18
11.04
mmol/l
0.04
11
67
21
164
1.29
0.47
2.5
3.8
—
—
—
0
0
13
95
1.38
0.44
1.6
2.3
59.13
116.61
ug/min
—
7
55
22
176
1.26
0.42
1.2
1.3
267.09
246.91
miu/ml
—
8
86
5
34
1.48
0.40
1.0
1.2
—
—
—
0
0
9
67
1.35
0.38
3.7
1.9
13.28
13.15
%
—
9
67
5
37
1.35
0.37
1.0
1.3
—
—
—
0
0
108
1007
1.09
0.33
3.4
3.3
1608.56
270.84
mg/l
0.84
79
658
9
116
0.77
0.27
1.3
1.6
—
—
—
0
0
8
65
1.23
0.27
1.6
1.1
—
—
—
0
0
31
272
1.15
0.26
1.3
1.2
—
—
—
0
0
9
76
1.19
0.24
1.6
1.7
—
—
—
0
0
5
40
1.25
0.22
1.2
1.8
—
—
—
0
0
5
40
1.25
0.22
1.8
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
5.6
—
—
—
0
0
0
10
0.00
0.21
0.0
2.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
9
113
0.79
0.20
1.3
1.5
—
—
—
0
0
15
176
0.85
0.20
2.6
2.2
—
—
—
0
0
9
114
0.79
0.20
1.3
1.4
—
—
—
0
0
29
322
0.89
0.19
2.0
1.7
—
—
—
0
0
14
118
1.19
0.19
1.1
1.2
—
—
—
0
0
6
52
1.16
0.19
1.0
1.2
—
—
—
0
0
11
91
1.21
0.17
1.1
1.1
3.71
2.16
u/ml
—
6
45
6
79
0.76
0.15
1.7
1.4
—
—
—
0
0
24
218
1.11
0.14
1.0
1.1
—
—
—
0
0
8
100
0.80
0.13
1.5
1.6
—
—
—
0
0
51
483
1.06
0.12
1.5
1.7
—
—
—
0
0
19
209
0.91
0.11
1.3
1.4
—
—
—
0
0
45
426
1.06
0.11
1.4
1.4
—
—
—
0
0
5
45
1.11
0.10
1.4
1.3
—
—
—
0
0
119
1161
1.03
0.09
3.2
3.1
8.26
7.99
mmol/l
0.27
108
998
21
224
0.93
0.07
1.3
1.4
—
—
—
0
0
16
173
0.92
0.07
1.3
1.4
—
—
—
0
0
9
103
0.87
0.06
1.0
1.1
—
—
—
0
0
21
223
0.94
0.06
1.3
1.4
—
—
—
0
0
21
223
0.94
0.06
1.3
1.4
—
—
—
0
0
21
222
0.94
0.05
1.3
1.4
—
—
—
0
0
414
4124
1.02
0.04
4.5
4.1
4.64
4.80
mmol/l
2.78
397
3896
14
150
0.93
0.04
1.4
1.6
—
—
—
0
0
16
151
1.06
0.03
2.3
1.6
—
—
—
0
0
14
132
1.06
0.02
13.7
8.1
—
—
—
0
0
419
4179
1.02
0.02
4.7
4.4
2.76
2.89
mmol/l
2.51
402
3922
96
950
1.01
0.02
4.8
4.3
3.28
1.90
ug/l
0.76
85
856
396
3967
0.99
0.01
4.0
3.7
1.40
1.29
mmol/l
1.71
378
3719
411
4115
0.99
0.00
4.4
4.0
1.48
1.47
mmol/l
0.08
393
3863
37
371
1.00
0.00
1.3
1.2
33.09
150.13
iu/ml
7.82
19
156
393
3935
0.99
0.00
4.2
4.1
5.88
5.84
mmol/l
0.25
372
3669
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
3.01
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.03
—
0
6
7
69
1.01
-0.00
1.7
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
18.31
—
0
9
0
6
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
12
120
1.00
-0.00
2.4
2.5
—
—
—
0
0
5
51
0.98
-0.00
2.8
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint ULCER_ARTHR and mortality.

Females

Parameter HR [95% CI] p-value
ULCER_ARTHR 1.403 [1.1, 1.79] 0.006
Birth year 0.996 [0.99, 1.0] 0.305

During the follow-up period (1.1.1998 — 31.12.2019), 62 out of 907 females with ULCER_ARTHR died.

Males

Parameter HR [95% CI] p-value
ULCER_ARTHR 1.167 [0.92, 1.49] 0.212
Birth year 0.991 [0.98, 1.0] 0.057

During the follow-up period (1.1.1998 — 31.12.2019), 80 out of 698 males with ULCER_ARTHR died.

Mortality risk

Mortality risk for people of age

years, who have ULCER_ARTHR.

N-year risk Females Males
1 0.127% 0.177%
5 0.763% 1.472%
10 1.952% 3.667%
15 3.853% 7.007%
20 6.948% 12.123%

Relationships between endpoints

Index endpoint: ULCER_ARTHR – Arthropathy in ulcerative colitis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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