Enteropathic arthropathies

M13_ENTEROARTHR

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

892

4. Check minimum number of events

None

892

5. Include endpoints

None

892

6. Filter based on genotype QC (FinnGen only)

892

Control definitions (FinnGen only)

Control exclude
M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3845 2119 1711
Only index persons 3646 2038 1608
Unadjusted period prevalence (%)
Whole population 0.05 0.06 0.05
Only index persons 0.07 0.07 0.06
Median age at first event (years)
Whole population 44.81 45.37 44.02
Only index persons 44.26 44.98 43.36

-FinnGen-

Key figures

All Female Male
Number of individuals 892 555 337
Unadjusted period prevalence (%) 0.17 0.19 0.15
Median age at first event (years) 44.96 43.65 47.12

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
811
Matched controls
8109
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
323.0
368
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
69.1
323.0
370
97
L04AX01
ATC
azathioprine; systemic
62.6
323.0
405
127
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
64.9
323.0
373
105
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
140.9
323.0
614
175
A07EC02
ATC
mesalazine; oral, rectal
84.7
323.0
556
203
A07EC01
ATC
sulfasalazine; oral, rectal
151.1
323.0
515
92
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
+∞
311.1
278
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
50.2
297.7
362
128
UJF32
NOMESCO Finland
Coloscopy
19.1
295.5
578
932
K51.5
ICD-10 Finland
Left sided colitis
51.4
267.9
323
103
A07EA06
ATC
budesonide; oral, local oral
49.2
252.4
307
99
H02AB06
ATC
prednisolone; systemic
14.9
234.0
682
2125
K50.9
ICD-10 Finland
Crohn disease, unspecified
115.7
231.2
244
30
K50.8
ICD-10 Finland
Other Crohn disease
99.1
226.8
244
35
A07EA02
ATC
hydrocortisone; rectal
48.7
191.0
232
66
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
51.5
189.9
228
61
K50.1
ICD-10 Finland
Crohn disease of large intestine
83.1
181.7
201
32
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
86.9
180.1
198
30
UJF30
NOMESCO Finland
Ileoscopy through colon
16.3
176.7
309
294
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
45.6
167.3
206
60
L04AB04
ATC
adalimumab; parenteral
96.6
166.8
181
24
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
161.3
162.3
167
13
K50.0
ICD-10 Finland
Crohn disease of small intestine
60.7
158.1
184
39
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
1824.3
157.6
148
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
8.3
157.5
465
1135
M13.9
ICD-10 Finland
Arthritis, unspecified
39.7
128.5
163
51
K51.8
ICD-10 Finland
Other ulcerative colitis
51.0
128.1
154
37
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
+∞
127.5
119
*
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
101.1
124.6
135
16
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
53.7
122.6
146
33
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
1322.3
120.0
114
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
83.3
114.4
127
18
H02AB07
ATC
prednisone; oral
8.5
113.0
282
479
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
89.2
110.9
122
16
J01MA02
ATC
ciprofloxacin; systemic
5.2
104.3
482
1773
P01BA02
ATC
hydroxychloroquine; oral
19.2
92.5
145
91
N02AX02
ATC
tramadol; systemic, rectal
4.7
91.4
448
1673
M25.5
ICD-10 Finland
Pain in joint
5.9
89.9
302
740
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
54.6
88.5
105
22
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.1
86.8
350
1050
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
9.3
85.8
193
263
L88
ICPC
Rheumatoid/seropositive arthritis
53.5
83.2
99
21
L01BB02
ATC
mercaptopurine; oral
47.4
82.1
100
24
ZX120
NOMESCO Finland
Intravenous
8.4
80.5
194
294
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
28.4
79.4
109
44
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.2
78.7
434
1734
P01AB01
ATC
metronidazole; oral, rectal
4.1
77.1
469
2034
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
+∞
74.1
70
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
15.2
69.1
118
90
M45
ICD-10 Finland
Ankylosing spondylitis
21.2
67.4
101
54
L40.5
ICD-10 Finland
Arthropathic psoriasis
105.9
62.9
68
7
UJF92
NOMESCO Finland
Capsular endoscopy
28.7
60.9
83
32
TPH04
NOMESCO Finland
Cathetrisation of vein
4.5
60.6
258
764
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
14.4
59.3
103
81
A02BC02
ATC
pantoprazole; systemic
3.5
58.5
581
3411
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
66.2
58.4
67
11
L04AA13
ATC
leflunomide; oral
313.6
58.0
58
*
K51
ICD-10 Finland
Ulcerative colitis
30.2
57.3
77
28
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
14.5
57.2
99
77
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
48.6
55.4
67
15
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
54.8
52
*
M07.3
ICD-10 Finland
Other psoriatic arthropathies
192.5
52.6
54
*
D94
ICPC
Chronic enteritis/ulcerative colitis
47.8
51.2
62
14
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
8.0
50.0
120
173
N02BE01
ATC
paracetamol; systemic, rectal
4.4
49.9
726
5344
L04AB06
ATC
golimumab; parenteral
66.7
48.9
56
9
A07EA01
ATC
prednisolone; rectal
55.6
48.4
57
11
4AA12
NOMESCO Finland
NA
135.8
48.4
51
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
4.1
48.0
215
649
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
108.7
47.3
51
5
M01AH01
ATC
celecoxib; oral (coxibs)
4.4
46.8
193
537
M19.0
ICD-10 Finland
Primary arthrosis of other joints
21.1
45.7
68
35
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
243.4
45.4
46
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
29.9
45.4
61
22
WX002
NOMESCO Finland
Sedation and analgesia
4.0
45.3
212
661
N02AJ06
ATC
codeine and paracetamol; systemic
3.0
45.2
361
1694
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.9
45.0
413
2123
M01AH05
ATC
etoricoxib; oral
2.9
44.7
518
3080
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
19.8
43.5
66
36
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
232.2
43.3
44
*
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
26.4
42.5
59
24
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
154.8
42.2
44
*
M16.1
ICD-10 Finland
Other primary coxarthrosis
25.9
41.6
58
24
L04AC05
ATC
ustekinumab; parenteral
81.3
41.3
46
6
7113L
ICD-9 Finland
Arthropathy associated with infections, Postdysenteric arthropathy[ENTEROARTHRITIS, USEAT NIVELET]
+∞
41.0
39
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
6.8
40.8
108
178
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
40.9
40.1
50
13
K50
ICD-10 Finland
Crohn disease [regional enteritis]
54.0
39.0
46
9
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
8.2
38.7
90
122
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
28.5
37.7
51
19
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
86.3
37.2
41
5
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
136.3
37.0
39
*
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
136.3
37.0
39
*
NH3EA
NOMESCO Finland
Feet X-ray examination with load
71.7
36.3
41
6
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
68.1
34.3
39
6
A02BC01
ATC
omeprazole; systemic
2.9
34.1
253
1085
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
12.8
34.0
61
51
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
33.7
332
1689
4AB02
NOMESCO Finland
NA
43.1
33.4
41
10
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
10.9
33.0
64
63
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.7
32.8
121
294
C10AC01
ATC
colestyramine; oral
9.5
31.5
66
75
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
88.7
31.0
34
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
7.6
30.7
74
106
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
60.8
30.3
35
6
N03AX16
ATC
pregabalin; oral
3.0
30.3
206
826
A02BC03
ATC
lansoprazole; oral
2.8
30.2
247
1112
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
19.8
29.9
45
24
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.0
29.2
128
365
A06AC01
ATC
ispaghula (psylla seeds); oral
2.9
29.1
217
920
A07DA03
ATC
loperamide; oral
8.7
29.1
64
79
NF1AA
NOMESCO Finland
Hip X-ray examination
8.6
28.9
64
80
M01AC06
ATC
meloxicam; systemic, rectal
2.5
28.8
301
1549
B01AB05
ATC
enoxaparin; parenteral
2.8
28.7
227
997
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
50.6
28.6
34
7
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
57.2
28.3
33
6
L04AB01
ATC
etanercept; parenteral
57.2
28.3
33
6
L40.0
ICD-10 Finland
Psoriasis vulgaris
7.4
28.2
69
101
D07AC01
ATC
betamethasone; topical
2.4
28.2
309
1630
L04AA01
ATC
[U] ciclosporin; systemic
23.3
28.1
40
18
A02BC05
ATC
esomeprazole; systemic
2.4
27.9
342
1908
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
150.1
27.8
29
*
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
20.5
27.6
41
21
Z01.8
ICD-10 Finland
Other specified special examinations
2.9
27.6
202
841
H02AB09
ATC
hydrocortisone; systemic
11.5
27.2
51
47
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.7
27.1
97
227
JF1BD
NOMESCO Finland
Very extensive small bowel CT
64.3
27.1
31
5
J01DB01
ATC
cefalexin; oral
2.7
27.1
685
5411
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.4
27.0
105
267
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
7.5
26.5
64
92
H02AB04
ATC
methylprednisolone; systemic
3.3
26.4
146
501
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
26.3
144
491
NG1DA
NOMESCO Finland
X-ray of knees
74.9
25.9
29
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.2
25.9
84
177
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
96.6
25.8
28
*
M01AH02
ATC
rofecoxib; oral
3.9
25.5
112
319
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
21.5
25.4
37
18
M01CB01
ATC
sodium aurothiomalate; parenteral
+∞
25.1
24
*
E0000UV
ATC
NA
2.2
24.8
351
2062
L04AD01
ATC
ciclosporin; systemic
10.2
24.6
49
51
WX320
NOMESCO Finland
Spinalanesthesy
3.1
24.1
149
552
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
+∞
24.1
23
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
23.5
238
1179
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
7.5
23.5
56
79
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
16.8
23.4
37
23
1370
FHL
Colonoscopy, whole colon
25.5
23.2
32
13
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
23.0
22
*
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
26.8
22.8
31
12
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.8
22.1
77
175
K60.3
ICD-10 Finland
Anal fistula
11.0
22.1
42
40
M074, L405
ICD-10 Finland
NA
+∞
22.0
21
*
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
64.4
22.0
25
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
21.9
330
1963
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.8
21.7
97
279
R03AC02
ATC
salbutamol; inhalant
2.1
21.4
434
2914
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.2
21.3
124
439
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
34.8
21.2
27
8
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
12.4
21.2
38
32
D05AX02
ATC
calcipotriol; topical
6.6
21.0
55
89
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
20.9
317
1880
B03BA03
ATC
hydroxocobalamin; parenteral
5.9
20.8
59
106
N03AX12
ATC
gabapentin; oral
3.2
20.8
120
420
R4110
NOMESCO Finland
Physiotherapy
2.4
20.7
210
1034
M03BX02
ATC
tizanidine; oral
2.0
20.6
517
3756
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.7
20.5
163
701
R50.9
ICD-10 Finland
Fever, unspecified
2.9
20.4
133
507
J01MA12
ATC
levofloxacin; systemic
2.7
20.3
157
664
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
5.8
20.0
58
107
M07.6
ICD-10 Finland
Other enteropathic arthropathies
+∞
19.9
19
*
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
+∞
19.9
19
*
JHA00
NOMESCO Finland
Anal or perianal incision
12.6
19.7
35
29
M17.5
ICD-10 Finland
Other secondary gonarthrosis
204.7
19.6
20
*
A07EC03
ATC
olsalazine; oral
41.2
19.6
24
6
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
16.1
19.4
31
20
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.3
19.2
104
348
M01AX17
ATC
nimesulide; oral
2.5
19.1
174
806
H04.10
ICD-10 Finland
Dry eye syndrome
3.3
19.0
101
334
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
18.8
18
*
TNG10
NOMESCO Finland
Puncture of knee
71.6
18.8
21
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.0
18.8
383
2528
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
39.4
18.6
23
6
JFB00
NOMESCO Finland
Partial resection of small intestine
11.8
18.6
34
30
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
15.5
18.6
30
20
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.1
18.5
254
1426
K56.7
ICD-10 Finland
Ileus, unspecified
12.2
18.4
33
28
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
30.8
18.4
24
8
K83.0
ICD-10 Finland
Cholangitis
11.0
18.1
34
32
ZX140
NOMESCO Finland
Intra articular
53.8
18.0
21
*
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
9.2
17.8
37
42
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
+∞
17.8
17
*
M13.0
ICD-10 Finland
Polyarthritis, unspecified
97.2
17.6
19
*
M79.6
ICD-10 Finland
Pain in limb
2.1
17.6
258
1483
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
183.8
17.6
18
*
L20
ICPC
Joint symptom/complaint NOS
7.0
17.5
43
64
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
12.3
17.4
31
26
M01AE02
ATC
naproxen; oral, rectal
1.9
17.3
451
3220
WX110
NOMESCO Finland
Local anesthesy
2.0
17.3
564
4369
J01FF01
ATC
clindamycin; systemic
2.2
17.1
221
1201
NF1DA
NOMESCO Finland
X-ray of hips
51.1
17.0
20
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.4
16.7
163
777
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
16.7
182
915
S18
ICPC
Laceration/cut
2.0
16.6
284
1731
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
7.8
16.6
38
51
3042
Kela drug reimbursment
NA
173.4
16.6
17
*
253
Kela drug reimbursment
NA
173.4
16.6
17
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
4.0
16.2
66
175
M05BA04
ATC
alendronic acid; oral
3.9
16.1
68
186
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
10.3
16.0
31
31
J01AA02
ATC
doxycycline; systemic
1.9
16.0
601
4822
M79.0
ICD-10 Finland
Rheumatism, unspecified
8.0
16.0
36
47
A02BA02
ATC
ranitidine; systemic
2.4
16.0
143
652
L15
ICPC
Knee symptom/complaint
2.6
15.9
129
556
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.6
15.9
73
215
NE1AA
NOMESCO Finland
Pelvis X-ray examination
5.4
15.8
48
94
JN3AD
NOMESCO Finland
Abdominal CT examination
3.6
15.8
72
211
WZA10
NOMESCO Finland
Long statement of health and health related matters
17.6
15.7
24
14
7113F
ICD-9 Finland
Arthropathy associated with infections, Postdysenteric arthropathy[ENTEROARTHRITIS, POLVI]
+∞
15.7
15
*
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
+∞
15.7
15
*
5551A
ICD-9 Finland
Regional enteritis, Large intestine
86.8
15.6
17
*
N05CF01
ATC
zopiclone; oral
2.0
15.6
236
1365
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.5
15.2
74
228
XX9XE
NOMESCO Finland
Other ultrasound examination
29.2
15.2
20
7
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
4.2
15.0
57
142
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
57.8
14.8
17
*
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
7.7
14.8
34
46
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
4.6
14.8
52
120
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
5.3
14.8
45
89
D07AD01
ATC
clobetasol; topical
2.4
14.6
137
637
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
+∞
14.6
14
*
L04AB05
ATC
certolizumab pegol; parenteral
81.6
14.6
16
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.1
14.6
58
151
M54.5
ICD-10 Finland
Low back pain
1.9
14.5
253
1540
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
14.4
229
1345
M13.8
ICD-10 Finland
Other specified arthritis
43.3
14.1
17
*
M20.2
ICD-10 Finland
Hallux rigidus
43.3
14.1
17
*
M20.1
ICD-10 Finland
Hallux valgus (acquired)
7.4
14.1
33
46
B81
ICPC
Anaemia vit B12/folate deficiency
6.1
14.1
38
65
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
7.7
14.0
32
43
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
54.3
13.8
16
*
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
24.3
13.8
19
8
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
13.8
567
4553
K92.1
ICD-10 Finland
Melaena
4.5
13.7
48
111
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.8
13.6
59
166
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
76.4
13.6
15
*
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
34.7
13.5
17
5
L04AA29
ATC
tofacitinib; oral
142.2
13.5
14
*
3005
Kela drug reimbursment
Tofacitinib
142.2
13.5
14
*
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
18.6
13.4
20
11
JFF10
NOMESCO Finland
Loop enterostomy
26.2
13.4
18
7
JFH10
NOMESCO Finland
Total colectomy and ileostomy
26.2
13.4
18
7
Z93.2
ICD-10 Finland
Ileostomy status
21.6
13.4
19
9
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
13.3
77
270
J02AC01
ATC
fluconazole; systemic
1.8
13.3
328
2232
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
14.1
13.3
22
16
M01AB55
ATC
diclofenac, combinations; oral
4.2
13.2
50
125
M02AA07
ATC
piroxicam; topical
1.9
13.2
240
1473
JFB20
NOMESCO Finland
Ileocaecal resection
15.4
13.1
21
14
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
15.4
13.1
21
14
J01FA10
ATC
azithromycin; systemic
1.7
13.1
470
3582
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.9
13.1
260
1646
J01CA04
ATC
amoxicillin; systemic
1.9
13.0
645
5446
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.6
13.0
100
417
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.6
13.0
103
437
JAH00
NOMESCO Finland
Laparotomy
5.8
13.0
36
64
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.6
12.7
98
410
ZXA00
NOMESCO Finland
Right side
2.1
12.6
161
856
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
71.0
12.6
14
*
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
71.0
12.6
14
*
AA1AD
NOMESCO Finland
CT of head and brain
2.1
12.6
153
797
M25.4
ICD-10 Finland
Effusion of joint
32.6
12.6
16
5
K61.0
ICD-10 Finland
Anal abscess
7.5
12.6
29
40
N06AX11
ATC
mirtazapine; oral
1.9
12.5
241
1500
N02AA05
ATC
oxycodone; systemic
2.7
12.5
88
348
6960A
ICD-9 Finland
Psoriasis and similar disorders, Psoriatic arthropathy
+∞
12.5
12
*
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
+∞
12.5
12
*
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
12.5
12
*
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
+∞
12.5
12
*
R4120
NOMESCO Finland
Occupational therapy
3.7
12.4
54
153
SAA02
NOMESCO Finland
Basic examination of mouth
1.7
12.4
516
4079
E000001
ATC
NA
2.0
12.4
176
982
M01AX01
ATC
nabumetone; oral
4.5
12.4
43
99
M01AH03
ATC
valdecoxib; oral
3.6
12.3
55
159
R06.0
ICD-10 Finland
Dyspnoea
2.1
12.3
159
851
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
38.2
12.2
15
*
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.6
12.1
55
161
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.6
12.1
41
92
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
18.4
12.1
18
10
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.3
12.1
60
189
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
7.7
12.0
27
36
SPAT1153
SPAT
Removal of sutures
1.9
12.0
198
1165
M22.4
ICD-10 Finland
Chondromalacia patellae
13.6
12.0
20
15
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
47.4
11.9
14
*
WVA20
NOMESCO Finland
Medicine administration
6.0
11.9
32
55
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.6
11.8
87
354
JHD20
NOMESCO Finland
Incision of fistula-in-ano
10.7
11.8
22
21
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.0
11.6
46
120
JFH11
NOMESCO Finland
Laparoscopic colectomy
65.9
11.6
13
*
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
19.2
11.6
17
9
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.1
11.6
65
221
D05AX52
ATC
calcipotriol, combinations; topical
3.7
11.6
51
146
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
11.6
298
2032
C03CA01
ATC
furosemide; systemic
2.1
11.5
142
745
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
11.5
11
*
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
+∞
11.5
11
*
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
+∞
11.5
11
*
1220
FHL
Arthroscopy
6.5
11.5
29
46
TQW40
NOMESCO Finland
Remowal of suture of skin
3.4
11.5
55
169
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
8.0
11.4
25
32
3AC01
NOMESCO Finland
NA
10.7
11.3
21
20
WZA90
NOMESCO Finland
Other doctors statement
2.0
11.3
173
988
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
5.6
11.3
32
59
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
3.9
11.2
46
124
WX402
NOMESCO Finland
General anaesthesia
2.1
11.2
142
753
S97
ICPC
Chronic ulcer skin
4.3
11.2
41
100
N06AA09
ATC
amitriptyline; systemic
2.9
11.2
69
253
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
11.1
182
1067
ZXA05
NOMESCO Finland
Left side
2.1
11.1
143
765
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
11.1
380
2804
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
10.2
11.0
21
21
WZA00
NOMESCO Finland
Short statement of of health and health related matters
3.4
10.9
53
165
A05AA02
ATC
ursodeoxycholic acid; oral
5.5
10.8
31
58
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
4.4
10.8
38
89
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
10.8
310
2171
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
10.7
127
655
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
10.7
174
1016
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.1
10.7
60
204
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
10.7
75
298
J01FA06
ATC
roxithromycin; oral
1.7
10.6
300
2085
NG1EA
NOMESCO Finland
Knee X-ray examination with wrench
60.8
10.6
12
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
10.6
171
996
A07AA09
ATC
vancomycin; oral
10.2
10.5
20
20
Z50.1
ICD-10 Finland
Other physical therapy
3.9
10.5
42
111
A02BA04
ATC
nizatidine; systemic
3.1
10.5
56
187
L04AC10
ATC
secukinumab; parenteral
111.4
10.4
11
*
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
111.4
10.4
11
*
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
111.4
10.4
11
*
R06AE07
ATC
cetirizine; oral
1.7
10.4
333
2397
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
10.4
10
*
L04AA17
ATC
[U] adalimumab; parenteral
+∞
10.4
10
*
M075, K509
ICD-10 Finland
NA
+∞
10.4
10
*
NDG30
NOMESCO Finland
Fusion of wrist, total
+∞
10.4
10
*
M07.0
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
10.4
10
*
TNC11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in elbow joint
+∞
10.4
10
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.4
10.4
37
88
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
16.3
10.4
16
10
SPAT1310
SPAT
Counselling related to known health issue
1.8
10.3
226
1456
R51.80
ICD-10 Finland
Headache
2.2
10.3
117
589
R11
ICD-10 Finland
Nausea and vomiting
2.8
10.3
65
243
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
6.8
10.3
25
38
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.2
10.2
53
173
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
10.2
50
157
D07XC01
ATC
betamethasone, combinations; topical
2.3
10.2
99
467
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.6
10.2
413
3160
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.6
10.2
426
3287
D07AC13
ATC
mometasone; topical
1.8
10.1
220
1411
D07AB08
ATC
desonide; topical
2.3
10.1
93
425
H15.1
ICD-10 Finland
Episcleritis
8.6
10.1
21
25
X59
ICD-10 Finland
Exposure to unspecified factor
2.1
10.1
126
664
N06AX21
ATC
duloxetine; oral
2.5
10.1
82
351
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.1
10.0
38
96
J05AB11
ATC
valaciclovir; oral
2.2
10.0
109
541
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.2
10.0
102
491
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
10.0
184
1119
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.5
9.9
77
324
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.4
9.9
25
40
UJD02
NOMESCO Finland
Gastroscopy
3.6
9.9
44
128
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
12.4
9.9
17
14
D64.9
ICD-10 Finland
Anaemia, unspecified
2.7
9.9
66
255
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
9.9
116
593
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
26.4
9.8
13
5
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
26.4
9.8
13
5
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
6.6
9.8
24
37
A07AA02
ATC
nystatin; oral
3.3
9.8
48
151
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
55.7
9.7
11
*
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
55.7
9.7
11
*
M79.1
ICD-10 Finland
Myalgia
2.2
9.7
96
458
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
9.6
157
914
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
9.6
115
595
H20.1
ICD-10 Finland
Chronic iridocyclitis
8.5
9.6
20
24
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
11.5
9.6
17
15
M10.9
ICD-10 Finland
Gout, unspecified
6.1
9.6
25
42
D05AX03
ATC
calcitriol; topical
9.2
9.6
19
21
UJF02
NOMESCO Finland
Peroral enteroscopy
15.2
9.5
15
10
M01AB05
ATC
diclofenac; systemic, rectal
1.6
9.5
486
3919
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
30.4
9.4
12
*
M075, K515
ICD-10 Finland
NA
+∞
9.4
9
*
M01CB03
ATC
auranofin; oral
+∞
9.4
9
*
M075, L405
ICD-10 Finland
NA
+∞
9.4
9
*
M02.1
ICD-10 Finland
Postdysenteric arthropathy
+∞
9.4
9
*
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
+∞
9.4
9
*
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
9.4
9
*
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
+∞
9.4
9
*
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
+∞
9.4
9
*
JF1CM
NOMESCO Finland
Small bowel extensive MRI with with high intensity magnet
+∞
9.4
9
*
M35.7
ICD-10 Finland
Hypermobility syndrome
12.5
9.4
16
13
N05BA04
ATC
oxazepam; oral
1.8
9.4
188
1173
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.3
9.3
86
394
J01DA01
ATC
[U] cefalexin; systemic
1.6
9.3
461
3677
RD210
NOMESCO Finland
NA
5.8
9.3
25
44
M01AX05
ATC
glucosamine; oral
2.5
9.2
74
317
L12
ICPC
Hand/finger symptom/complaint
2.1
9.1
103
518
UJG02
NOMESCO Finland
Proctoscopy
5.2
9.1
27
53
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
6.4
9.1
23
37
J05AB01
ATC
aciclovir; systemic
1.8
9.1
161
962
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
9.1
252
1727
SPAT1262
SPAT
Handing over of treatment supplies
2.0
9.1
128
706
K76.9
ICD-10 Finland
Liver disease, unspecified
7.2
9.1
21
30
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
9.1
84
386
S01FA04
ATC
cyclopentolate; ophthalmic
9.2
9.1
18
20
M04AA01
ATC
allopurinol; systemic
2.7
9.0
61
237
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
37.1
9.0
11
*
5550A
ICD-9 Finland
Regional enteritis, Small intestine
37.1
9.0
11
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.7
9.0
213
1394
G44.2
ICD-10 Finland
Tension-type headache
2.1
9.0
102
513
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
6.2
9.0
23
38
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
24.3
8.9
12
5
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.9
8.9
28
59
L16
ICPC
Ankle symptom/complaint
2.5
8.9
67
278
WW200
NOMESCO Finland
Immunization
4.4
8.9
31
73
KMAK
NOMESCO Finland
NA
1.6
8.9
408
3182
A06AD11
ATC
lactulose; oral
2.3
8.8
81
372
L17
ICPC
Foot/toe symptom/complaint
1.8
8.8
154
917
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.6
8.8
451
3605
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
8.7
8.8
18
21
SPAT1263
SPAT
Sampling
1.6
8.8
299
2158
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
10.9
8.8
16
15
L28
ICPC
Limited function/disability (L)
2.3
8.8
82
377
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
7.3
8.8
20
28
K02.1
ICD-10 Finland
Caries of dentine
1.6
8.7
443
3532
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.2
8.7
32
79
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
8.7
120
655
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.7
8.7
193
1238
J01FA09
ATC
clarithromycin; systemic
1.7
8.7
235
1594
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
50.5
8.7
10
*
ACC51
NOMESCO Finland
Release of median nerve
2.9
8.7
51
183
R52.9
ICD-10 Finland
Pain, unspecified
2.6
8.6
63
257
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.2
8.6
90
437
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
27.8
8.5
11
*
B01AX06
ATC
[U] rivaroxaban; oral
27.8
8.5
11
*
M47.82
ICD-10 Finland
Other spondylosis, cervical region
4.4
8.5
29
67
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.2
8.5
88
428
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
20.3
8.5
12
6
NG2AA
NOMESCO Finland
Patella X-ray examination
20.3
8.5
12
6
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
7.5
8.5
19
26
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
90.9
8.4
9
*
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.7
8.4
27
59
R01AD12
ATC
fluticasone furoate; nasal
1.6
8.3
237
1629
L04AA33
ATC
vedolizumab; parenteral
+∞
8.3
8
*
NH3AE
NOMESCO Finland
Feet ultrasound examination
+∞
8.3
8
*
M06
ICD-10 Finland
Other rheumatoid arthritis
+∞
8.3
8
*
7350A
ICD-9 Finland
Acquired deformities of toe, Hallux valgus (acquired)
+∞
8.3
8
*
M076, L405
ICD-10 Finland
NA
+∞
8.3
8
*
M19.9
ICD-10 Finland
Arthrosis, unspecified
5.9
8.3
22
38
A01AB09
ATC
miconazole; local oral
2.5
8.3
64
269
R52.2
ICD-10 Finland
Other chronic pain
4.6
8.2
27
60
SPAT1325
SPAT
Vaccination
1.7
8.2
221
1496
R01AD09
ATC
mometasone; nasal
1.6
8.2
337
2544
K07.60
ICD-10 Finland
Snapping jaw
3.1
8.1
43
144
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
8.1
140
830
JHD30
NOMESCO Finland
Incomplete incision of fistula-in-ano
33.7
8.1
10
*
M25.9
ICD-10 Finland
Joint disorder, unspecified
17.4
8.1
12
7
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
8.1
379
2946
WX290
NOMESCO Finland
Other blockade of nerve
1.5
8.1
352
2690
S01FA02
ATC
scopolamine; ophthalmic
10.2
8.0
15
15
Z93
ICD-10 Finland
Artificial opening status
22.3
8.0
11
5
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.2
8.0
40
129
R4190
NOMESCO Finland
Nutritional therapy
3.5
8.0
35
102
A03CA02
ATC
clidinium and psycholeptics; oral
3.1
7.9
42
141
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
3.1
7.9
41
136
N05CF02
ATC
zolpidem; oral
1.8
7.9
136
804
L13
ICPC
Hip symptom/complaint
2.2
7.8
76
357
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
10.9
7.8
14
13
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
4.9
7.8
24
50
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
2.9
7.8
45
159
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.1
7.8
40
132
XA402
NOMESCO Finland
ENMG
6.5
7.7
19
30
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
15.2
7.7
12
8
M06.4
ICD-10 Finland
Inflammatory polyarthropathy
45.4
7.7
9
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
7.7
119
675
E66.01
ICD-10 Finland
Obesity due to excess calories
2.5
7.7
59
247
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
7.6
60
256
107
Kela drug reimbursment
Pernicious anaemia
6.8
7.6
18
27
D11
ICPC
Diarrhoea
2.1
7.6
90
462
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
12.0
7.6
13
11
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
25.3
7.6
10
*
R02
ICPC
Shortness of breath/dyspnoea
2.2
7.6
74
348
SBA00
NOMESCO Finland
Microbiological examinations
4.6
7.4
24
53
6419
FHL
Other measure in this category
80.8
7.4
8
*
M17.4
ICD-10 Finland
Other secondary gonarthrosis, bilateral
80.8
7.4
8
*
M02.8
ICD-10 Finland
Other reactive arthropathies
80.8
7.4
8
*
NF2AT
NOMESCO Finland
Injection to hip joint with ultrasound guidance
80.8
7.4
8
*
M09AX01
ATC
hyaluronic acid; parenteral
7.7
7.4
16
21
R35
ICD-10 Finland
Polyuria
2.8
7.4
45
166
C05AA08
ATC
fluocortolone; rectal, topical
1.9
7.4
108
603
UKC02
NOMESCO Finland
Cystoscopy
2.0
7.4
91
477
K56.0
ICD-10 Finland
Paralytic ileus
8.5
7.3
15
18
M02AA10
ATC
ketoprofen; topical
2.0
7.3
100
544
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
6.9
7.3
17
25
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.2
7.3
37
121
M074, K508
ICD-10 Finland
NA
+∞
7.3
7
*
M073, K519
ICD-10 Finland
NA
+∞
7.3
7
*
M07.2*L40.5
ICD-10 Finland
Psoriatic spondylitis
+∞
7.3
7
*
291
Kela drug reimbursment
Tofacitinib
+∞
7.3
7
*
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
+∞
7.3
7
*
212
Kela drug reimbursment
Gout
+∞
7.3
7
*
WX111
NOMESCO Finland
Local infiltration anesthesia
+∞
7.3
7
*
R03DC03
ATC
montelukast; oral
1.9
7.3
114
650
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
6.3
7.3
18
29
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.1
7.2
37
122
WZC30
NOMESCO Finland
Teaching
2.0
7.2
95
508
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
7.4
7.2
16
22
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
30.3
7.2
9
*
M22.0
ICD-10 Finland
Recurrent dislocation of patella
30.3
7.2
9
*
4AA33
NOMESCO Finland
NA
30.3
7.2
9
*
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
30.3
7.2
9
*
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
7.1
99
543
1490
FHL
Sigmoideoscopy (fiberscope)
20.2
7.1
10
5
D02AE01
ATC
carbamide; topical
2.5
7.1
53
219
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
4.6
7.1
23
51
B01AF01
ATC
rivaroxaban; oral
2.8
7.1
45
168
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
7.1
128
768
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
7.0
166
1077
L01
ICPC
Neck symptom/complaint
1.9
7.0
96
523
K59.1
ICD-10 Finland
Functional diarrhoea
2.9
7.0
41
147
M67.4
ICD-10 Finland
Ganglion
2.7
7.0
45
172
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
13.9
6.9
11
8
L52
ICD-10 Finland
Erythema nodosum
13.9
6.9
11
8
M81.4
ICD-10 Finland
Drug-induced osteoporosis
13.9
6.9
11
8
S29
ICPC
Skin symptom/complaint other
1.9
6.9
102
571
M54.4
ICD-10 Finland
Lumbago with sciatica
1.9
6.9
109
626
A02BX02
ATC
sucralfate; oral
3.6
6.8
29
83
E86
ICD-10 Finland
Volume depletion
5.1
6.8
20
40
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.1
6.8
35
116
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
9.4
6.8
13
14
L43.8
ICD-10 Finland
Other lichen planus
5.4
6.8
19
36
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
6.2
6.8
17
28
L73.2
ICD-10 Finland
Hidradenitis suppurativa
6.2
6.8
17
28
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
6.8
161
1049
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.9
6.8
39
138
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
6.8
319
2449
N20.1
ICD-10 Finland
Calculus of ureter
3.3
6.8
32
100
L01BB01
ATC
NA
40.4
6.8
8
*
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
40.4
6.8
8
*
M18.0
ICD-10 Finland
Primary arthrosis of first carpometacarpal joints, bilateral
16.8
6.8
10
6
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.7
6.7
27
74
M23.8
ICD-10 Finland
Other internal derangements of knee
7.3
6.7
15
21
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.9
6.7
26
69
G47.3
ICD-10 Finland
Sleep apnoea
1.7
6.7
142
895
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
5.0
6.7
20
41
9271
FHL
Hallux surgery
22.7
6.7
9
*
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
22.7
6.7
9
*
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
22.7
6.7
9
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
6.6
274
2044
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.6
6.6
28
80
EBA00
NOMESCO Finland
Extraction of tooth
1.6
6.6
229
1640
D01
ICPC
Abdominal pain/cramps general
2.1
6.6
71
352
M01AE52
ATC
naproxen and esomeprazole; oral
3.8
6.6
26
70
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.7
6.5
137
861
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
6.5
310
2385
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
70.4
6.4
7
*
NHG22
NOMESCO Finland
Fusion of subtalar joint
70.4
6.4
7
*
G56.2
ICD-10 Finland
Lesion of ulnar nerve
4.1
6.4
23
57
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
7.5
6.4
14
19
TJF80
NOMESCO Finland
Ostomy education
7.5
6.4
14
19
F43.29
ICD-10 Finland
Adaptation disorder UNS
3.7
6.4
26
72
Z71.8
ICD-10 Finland
Other specified counselling
1.6
6.4
170
1138
-69
ICPC
Other reason for encounter NEC
3.2
6.4
31
99
L90
ICPC
Osteoarthrosis of knee
5.0
6.4
19
39
A46
ICD-10 Finland
Erysipelas
2.0
6.4
77
400
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
6.4
73
372
M01AB01
ATC
indometacin; systemic, rectal
2.8
6.4
39
146
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
6.6
6.4
15
23
UJF34
NOMESCO Finland
Left colonoscopy
9.3
6.3
12
13
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.6
6.3
44
175
M87.0
ICD-10 Finland
Idiopathic aseptic necrosis of bone
18.2
6.3
9
5
7140B
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SERONEGATIVA]
+∞
6.3
6
*
M46.8
ICD-10 Finland
Other specified inflammatory spondylopathies
+∞
6.3
6
*
TND10
NOMESCO Finland
Joint puncture, wrist or finger joint
+∞
6.3
6
*
7177A
ICD-9 Finland
Internal derangement of knee, Chondromalacia of patella
+∞
6.3
6
*
M16.7
ICD-10 Finland
Other secondary coxarthrosis
+∞
6.3
6
*
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
+∞
6.3
6
*
NHG82
NOMESCO Finland
Fusion of other tarsal joint
+∞
6.3
6
*
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
+∞
6.3
6
*
M07.1*L40.5
ICD-10 Finland
Arthritis mutilans
+∞
6.3
6
*
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
+∞
6.3
6
*
M074K
ICD-10 Finland
NA
+∞
6.3
6
*
L04AA11
ATC
[U] etanercept; parenteral
+∞
6.3
6
*
7113X
ICD-9 Finland
Arthropathy associated with infections, Postdysenteric arthropathy[ENTEROARTHRITIS, MÄÄRITTELEMÄTÖN]
+∞
6.3
6
*
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.8
6.3
19
40
A06AC51
ATC
ispaghula, combinations; systemic
2.9
6.3
36
128
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
26.9
6.2
8
*
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
26.9
6.2
8
*
M19.2
ICD-10 Finland
Other secondary arthrosis
26.9
6.2
8
*
L40.9
ICD-10 Finland
Psoriasis, unspecified
7.1
6.2
14
20
J01MA14
ATC
moxifloxacin; systemic
2.2
6.2
63
304
M79.7
ICD-10 Finland
Fibromyalgia
4.0
6.2
23
59
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.8
6.2
97
555
C09CA06
ATC
candesartan; oral
1.7
6.2
139
891
K12.00
ICD-10 Finland
Recurrent oral aphthae
6.3
6.2
15
24
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
5.8
6.2
16
28
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.5
6.2
47
198
K60.2
ICD-10 Finland
Anal fissure, unspecified
4.7
6.1
19
41
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
6.1
92
517
-1
NOMESCO Finland
NA
1.5
6.1
243
1793
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
4.9
6.1
18
37
S91
ICPC
Psoriasis
8.7
6.1
12
14
B01AA03
ATC
warfarin; systemic
1.9
6.0
88
489
5BA08
NOMESCO Finland
NA
10.1
6.0
11
11
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
5.2
6.0
17
33
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
6.0
66
329
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.9
6.0
35
126
K60.0
ICD-10 Finland
Acute anal fissure
6.1
6.0
15
25
D05BB02
ATC
acitretin; oral
4.6
6.0
19
42

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
476
717
13.09
307.65
2.3
1.3
—
—
—
0
0
612
852
20.70
307.65
8.2
2.4
174.3
119.3
ug/g
3.28
585
674
711
2588
9.61
203.86
9.8
5.0
36.3
36.2
g/l
0.22
695
2422
612
2048
7.33
186.77
14.7
5.2
—
—
—
0
0
774
3242
11.49
186.31
18.1
5.1
0.6
0.6
e9/l
2.77
747
2817
775
3253
11.54
186.05
18.3
5.1
0.0
0.0
e9/l
2.43
748
2827
783
3375
11.80
180.99
18.4
5.5
0.2
0.2
e9/l
0.24
756
2971
778
3369
11.24
177.58
18.3
5.2
2.0
2.0
e9/l
0.09
755
2983
665
2678
6.83
156.53
4.3
2.2
73.6
74.6
nmol/l
0.40
651
2454
697
2966
7.18
152.76
18.2
5.2
0.7
0.7
%
2.09
688
2779
795
3849
10.80
150.42
19.9
9.0
4.0
4.0
e9/l
0.00
769
3374
705
3071
7.18
149.11
18.7
5.4
8.7
8.4
%
1.59
696
2890
327
737
6.43
147.75
1.7
1.3
660.8
475.5
titre
0.85
104
133
700
3052
7.01
147.17
18.3
5.2
2.8
2.8
%
0.22
690
2857
709
3148
7.10
145.26
17.5
5.0
56.9
56.6
%
0.31
700
2967
709
3206
6.91
140.33
18.5
5.2
29.1
28.7
%
0.53
700
3005
149
174
10.08
120.86
1.1
1.0
—
—
—
0
0
228
440
6.62
118.86
6.7
4.4
0.0
0.9
%
0.60
62
103
243
500
6.31
118.58
6.6
4.4
0.5
1.0
%
2.42
75
141
440
1499
4.82
118.48
4.2
1.9
2.9
2.8
mg/l
0.32
407
1254
235
473
6.39
117.24
6.8
4.4
0.0
0.2
%
3.32
72
131
230
456
6.45
116.50
6.0
4.2
0.4
0.6
%
0.71
61
99
86
43
22.03
113.78
1.6
1.0
—
—
—
0
0
308
846
5.03
107.35
1.4
1.1
11.1
1.5
u/ml
1.41
108
381
437
1584
4.45
106.06
12.1
4.2
—
—
—
0
0
815
4749
9.30
105.37
11.0
3.0
12.7
10.4
mm/h
6.17
798
4385
836
5046
11.46
102.32
21.0
6.9
74.5
76.1
u/l
0.81
826
4756
622
2991
4.57
100.28
20.0
7.8
0.0
0.0
e9/l
0.73
584
2442
70
35
21.62
92.33
1.9
1.1
9237.4
15833.3
e6/l
0.40
58
27
105
112
10.49
90.39
5.3
3.0
3.8
4.0
e9/l
0.42
105
112
299
914
4.42
88.97
1.4
1.2
24.5
16.3
iu/ml
0.88
93
271
105
115
10.22
88.63
5.4
3.5
56.5
56.3
%
0.06
105
115
58
20
30.95
87.68
1.7
1.1
—
—
—
0
0
52
17
32.42
79.82
1.8
1.1
48.9
67.8
%
—
35
10
271
841
4.19
77.85
1.5
1.6
—
—
—
0
0
244
756
4.07
69.47
2.7
2.4
21.1
24.5
%
2.93
215
655
590
3194
3.50
69.47
5.2
3.0
0.0
0.0
estimate
0.00
152
590
592
3215
3.50
69.26
6.7
4.3
0.0
0.0
estimate
0.50
164
603
595
3243
3.51
69.17
5.2
3.0
0.0
0.0
estimate
0.05
160
571
269
901
3.84
68.37
2.8
2.3
12.5
14.4
umol/l
3.54
263
829
253
815
3.94
68.02
2.7
2.3
2.4
2.4
g/l
0.55
247
764
373
1602
3.28
63.34
12.8
6.5
—
—
—
0
0
155
377
4.77
60.14
1.5
1.2
—
—
—
0
0
708
4517
3.75
59.46
6.6
3.5
—
—
—
0
0
562
3145
3.13
58.73
4.6
2.6
103.0
114.4
ug/l
0.56
544
2945
530
2935
2.99
55.23
6.1
7.2
1.2
1.2
mmol/l
0.05
446
2483
301
1241
3.15
53.25
1.6
1.7
—
—
—
0
0
450
2330
2.88
52.35
2.2
1.8
95.6
95.3
pmol/l
0.05
298
1237
572
3369
2.95
51.94
7.3
6.4
9.9
11.3
umol/l
2.52
549
3198
364
1703
2.92
50.93
3.8
4.0
7.4
7.4
ph
0.14
66
324
165
479
4.00
50.30
2.3
2.7
11.8
10.6
g/l
2.97
151
439
42
27
16.27
48.86
1.8
1.0
—
—
—
0
0
476
2621
2.75
47.90
5.6
6.3
1.2
1.2
mmol/l
0.10
436
2375
95
185
5.63
47.31
1.4
1.2
61.4
85.6
titre
—
7
18
95
187
5.57
46.75
1.4
1.2
—
1346.0
—
0
5
139
375
4.21
46.69
1.7
1.7
1.4
1.5
g/l
0.22
128
347
390
1990
2.71
44.94
4.7
2.4
60.8
57.3
u/l
0.77
371
1850
102
231
4.86
42.68
1.8
1.3
11.3
8.2
u/ml
—
9
5
97
211
5.04
42.57
1.3
1.2
0.3
1.4
u/ml
—
6
11
419
2281
2.58
41.44
9.1
6.7
1.1
1.2
inr
1.10
172
712
404
2177
2.56
40.62
4.1
3.3
43.9
101.2
e6/l
1.34
304
1489
315
1512
2.67
40.15
5.2
4.1
—
—
—
0
0
334
1657
2.62
39.73
6.2
3.2
0.0
0.0
estimate
1.08
162
589
291
1355
2.70
39.28
4.6
3.1
—
—
—
0
0
31
17
18.86
38.80
1.4
1.0
10906.3
39063.6
e6/l
—
21
10
303
1487
2.57
36.28
2.5
2.3
2986.3
8196.1
umol/l
1.52
280
1314
159
561
3.23
35.29
3.0
2.3
0.2
0.2
g/l
0.87
145
532
190
754
2.93
34.30
2.2
2.0
—
—
—
0
0
861
7116
7.04
33.44
33.6
11.0
14.2
23.8
mg/l
31.71
815
5349
342
1839
2.39
32.96
3.5
2.8
173.0
53.3
e6/l
0.52
289
1386
315
1642
2.42
32.47
3.5
2.8
0.3
0.5
e6/l
2.07
259
1208
255
1233
2.50
30.76
3.1
2.3
5.3
7.4
e6/l
1.45
230
1076
259
1280
2.44
29.64
2.4
1.6
396.1
27894686.6
pmol/l
1.23
234
1097
551
3736
2.24
29.29
5.1
4.8
6.6
6.6
mmol/l
0.08
527
3446
338
1891
2.27
28.90
5.0
2.7
—
—
—
0
0
142
525
3.03
28.79
1.3
1.5
—
—
—
0
0
303
1625
2.31
28.61
3.3
2.8
—
—
—
0
0
779
6192
3.04
28.43
33.9
13.6
13.9
13.5
%
8.04
773
6055
153
607
2.84
27.21
2.5
2.1
312.4
381.5
nmol/l
4.16
144
568
251
1303
2.29
25.09
1.9
1.4
19.4
20.7
nmol/l
0.81
233
1135
284
1553
2.22
25.01
1.8
1.9
—
—
—
0
0
258
1360
2.26
24.83
5.7
3.2
1.0
1.0
kg/l
0.08
30
185
120
444
2.97
24.12
4.3
3.1
—
—
—
0
0
182
833
2.49
24.10
1.3
1.2
—
—
—
0
0
117
428
3.00
24.00
3.5
2.7
4.3
4.1
e9/l
0.35
95
353
429
2777
2.05
23.98
2.6
2.0
—
—
—
0
0
69
182
4.03
23.53
1.3
1.1
—
—
—
0
0
587
4280
2.09
23.33
5.3
3.7
244.4
1168.8
e6/l
0.84
11
63
363
2244
2.04
22.72
3.9
3.0
22.1
64.7
ng/l
1.52
211
1326
58
140
4.36
22.23
1.2
1.2
2.8
2.3
u/ml
—
5
20
34
51
6.89
21.80
1.5
1.1
354.3
230.0
titre
—
14
9
47
97
5.06
21.76
1.9
2.0
0.5
0.9
g/l
1.04
41
77
226
1198
2.19
20.99
3.2
2.5
548.3
543.0
mosm/kgh2o
0.12
202
1020
839
7242
3.67
20.97
21.7
12.5
139.2
139.7
mmol/l
7.23
825
7030
841
7277
3.72
20.78
21.7
12.6
3.9
3.9
mmol/l
3.70
825
7054
27
33
8.41
20.59
1.3
1.1
—
—
—
0
0
134
574
2.57
20.19
5.5
3.3
—
—
—
0
0
190
952
2.27
20.19
2.1
1.6
1267.4
1179.4
nmol/l
0.56
140
731
63
176
3.78
19.80
3.4
3.0
—
—
—
0
0
123
515
2.61
19.39
3.8
3.9
2.1
1.8
mmol/l
0.37
103
394
133
579
2.52
19.34
2.9
2.9
1.8
1.8
%
0.33
126
516
247
1398
2.06
19.10
1.7
1.4
2.9
2.3
g/l
4.46
175
909
43
92
4.86
19.09
2.6
3.7
0.6
1.5
%
2.29
30
75
136
609
2.46
18.59
2.7
2.3
47.5
118.5
u/l
0.43
121
518
277
1648
1.99
18.55
5.4
3.5
95.0
93.2
%
0.58
264
1601
868
7765
5.38
18.37
29.3
8.4
27.3
26.9
u/l
0.33
862
7529
424
2945
1.84
17.36
5.1
3.8
—
—
—
0
0
52
140
3.88
17.22
1.1
1.3
—
—
—
0
0
278
1719
1.90
16.24
2.0
2.0
124.8
243.3
u/l
2.27
267
1634
179
949
2.11
16.21
2.6
2.6
2.7
3.0
e6/l
0.22
113
494
148
746
2.18
15.19
1.5
1.5
—
—
—
0
0
137
687
2.17
14.20
2.2
1.6
—
—
—
0
0
64
225
2.99
13.98
1.2
1.1
—
—
—
0
0
96
418
2.45
13.82
2.1
3.0
77.2
71.8
e9/l
0.54
72
308
314
2107
1.76
13.56
3.2
3.7
2.3
2.4
mmol/l
3.92
296
1889
18
7
26.19
13.40
1.9
1.0
—
—
—
0
0
68
254
2.82
13.31
2.1
1.6
—
—
—
0
0
84
352
2.53
13.11
4.5
8.0
—
—
—
0
0
80
330
2.56
12.90
7.4
10.7
23.8
24.2
mmol/l
0.49
75
310
40
110
3.76
12.87
2.1
2.1
137.5
130.3
g/l
0.98
33
79
240
1508
1.81
12.85
1.8
1.7
0.9
1.1
mg/l
0.93
192
1097
44
134
3.40
12.18
1.3
1.3
336.8
229.7
u/ml
1.21
25
80
64
243
2.76
12.15
1.3
1.3
—
—
—
0
0
61
227
2.81
12.03
1.5
2.3
1.6
1.4
g/l
0.55
52
201
76
319
2.51
11.82
1.6
2.9
—
—
—
0
0
122
628
2.09
11.74
16.6
16.5
1.1
1.2
inr
0.52
21
100
143
781
1.99
11.70
4.9
6.3
1.0
1.0
mmol/l
0.04
138
730
288
1954
1.70
11.59
2.7
2.2
—
—
—
0
0
43
135
3.30
11.36
2.4
2.7
8.9
8.4
kpa
1.49
37
129
138
752
1.99
11.34
4.1
2.8
7.8
7.6
umol/l
0.04
128
658
49
168
3.03
11.19
1.7
1.4
285.4
297.4
ug/g
0.16
32
96
259
1722
1.71
11.16
3.6
2.6
—
—
—
0
0
36
103
3.60
10.96
1.1
1.1
—
—
—
0
0
167
981
1.86
10.95
3.3
3.8
0.8
0.8
mmol/l
3.43
157
926
748
6554
1.88
10.79
4.8
4.5
1.8
2.3
mu/l
0.93
700
6080
24
52
4.72
10.52
2.8
3.6
54.3
56.8
%
—
10
32
74
324
2.40
10.51
2.9
2.4
0.7
0.2
e6/l
0.52
74
315
101
507
2.12
10.35
7.0
11.6
120.9
122.3
g/l
0.30
96
492
67
283
2.48
10.29
4.4
3.1
—
—
—
0
0
22
47
4.77
9.81
1.8
1.4
—
—
—
0
0
115
618
1.99
9.79
6.7
10.2
1.2
1.1
mmol/l
0.08
82
486
15
22
6.92
9.75
3.2
3.5
—
—
—
0
0
94
476
2.09
9.41
2.8
3.3
1.2
1.2
mmol/l
0.02
78
399
33
99
3.42
9.38
2.3
2.7
3.8
6.2
u/ml
0.72
33
93
93
473
2.08
9.20
6.4
9.3
—
—
—
0
0
240
1637
1.64
9.11
1.3
1.2
0.9
1.9
u/ml
1.69
53
445
570
4737
1.56
9.07
3.8
3.2
—
—
—
0
0
834
7689
2.30
8.98
23.6
10.4
—
—
—
0
0
33
104
3.26
8.70
1.1
1.1
1.5
1.4
g/l
0.94
26
97
15
25
6.09
8.67
1.5
1.6
—
—
—
0
0
41
148
2.86
8.59
2.6
2.6
24.3
25.1
mmol/l
0.62
36
135
209
1397
1.65
8.52
3.1
3.1
1187.7
992.6
ng/l
0.42
185
1164
875
8290
3.91
8.30
43.8
16.1
279.6
254.6
e9/l
19.55
865
8069
237
1648
1.60
8.19
3.3
3.2
—
—
—
0
0
644
5558
1.57
8.18
4.1
3.9
14.7
14.6
pmol/l
0.60
593
5126
875
8299
3.85
8.10
43.8
16.1
4.4
4.6
e12/l
11.28
866
8063
875
8300
3.84
8.07
43.8
16.2
7.1
6.7
e9/l
3.39
866
8060
30
94
3.27
8.00
2.2
1.2
—
—
—
0
0
875
8304
3.82
7.98
43.9
16.2
134.3
136.9
g/l
6.83
870
8185
32
105
3.12
7.92
2.5
2.2
—
—
—
0
0
49
204
2.48
7.79
4.9
4.9
—
—
—
0
0
31
103
3.08
7.53
2.5
2.0
18.6
16.6
%
2.34
21
52
33
114
2.97
7.50
2.7
1.9
—
—
—
0
0
15
29
5.24
7.47
1.5
1.3
268.7
662.0
u/l
0.48
15
24
7
0
+∞
7.30
1.0
0.0
—
—
—
0
0
21
55
3.89
7.28
1.4
3.1
1.2
1.1
e9/l
0.17
15
34
73
371
2.05
7.25
4.2
2.5
—
—
—
0
0
31
109
2.91
6.85
1.0
1.0
—
—
—
0
0
17
41
4.21
6.57
1.0
1.0
—
—
—
0
0
21
61
3.50
6.31
1.1
1.4
—
—
—
0
0
31
115
2.76
6.23
1.1
1.0
—
—
—
0
0
41
175
2.41
6.23
4.2
13.1
1.3
1.3
mmol/l
0.14
36
155
19
52
3.71
6.22
1.5
1.3
—
—
—
0
0
100
594
1.77
6.21
3.7
4.6
4.1
24.8
ug/l
1.01
73
489
24
78
3.13
6.08
1.5
1.5
—
—
—
0
0
17
44
3.92
6.01
1.0
1.0
—
—
—
0
0
68
365
1.93
5.82
1.1
1.1
—
145.1
—
0
9
77
431
1.86
5.81
3.2
4.3
87.6
83.7
ng/l
0.11
67
388
20
60
3.39
5.74
2.5
4.6
—
—
—
0
0
27
98
2.81
5.67
1.7
2.4
16.1
5.1
umol/l
0.86
22
71
132
866
1.62
5.66
1.4
1.3
—
—
—
0
0
14
33
4.29
5.57
1.5
1.2
140.8
144.1
nmol/l
0.07
14
33
77
438
1.83
5.53
1.2
1.2
123.1
243.5
u/ml
0.93
71
397
35
148
2.42
5.45
1.4
1.2
—
—
—
0
0
30
118
2.60
5.42
2.8
2.4
—
—
—
0
0
16
43
3.77
5.38
1.4
2.3
15.7
13.0
%
—
7
21
48
234
2.11
5.36
4.1
3.5
15.6
5627.8
u/ml
0.76
43
208
28
107
2.67
5.35
1.3
1.3
—
—
—
0
0
200
1456
1.48
5.35
2.6
2.1
—
—
—
0
0
29
114
2.60
5.25
1.4
4.6
—
—
—
0
0
8
6
13.44
5.08
1.1
1.3
—
—
—
0
0
756
6988
1.54
5.03
28.5
11.9
39.2
40.3
%
2.61
547
5468
64
355
1.86
4.99
2.9
3.4
7.4
7.4
ph
0.66
15
39
17
51
3.38
4.90
1.2
2.7
3.0
1.8
u/field
0.25
11
22
64
358
1.85
4.87
2.9
3.4
4.9
5.1
kpa
1.18
57
341
9
10
9.08
4.79
1.0
1.1
—
—
—
0
0
148
1041
1.51
4.65
2.4
3.1
2.4
2.4
mmol/l
0.40
135
930
37
173
2.19
4.62
1.7
2.5
8.2
11.1
mg/l
1.70
30
160
61
344
1.83
4.54
2.1
2.2
3910.2
5112.6
u/l
0.16
14
153
32
146
2.24
4.25
2.7
3.0
7.4
7.4
ph
1.88
24
113
11
27
4.11
4.17
1.1
1.2
—
—
—
0
0
73
446
1.69
4.15
2.9
3.6
4.4
4.5
pmol/l
0.69
68
405
697
6416
1.39
4.06
5.8
4.8
38.4
39.1
mmol/mol
1.10
671
5997
33
157
2.14
3.98
1.6
3.9
40.6
42.3
mg/l
0.09
27
132
31
145
2.18
3.90
1.3
1.6
—
—
—
0
0
29
134
2.20
3.77
2.5
3.5
37.0
33.5
umol/l
0.41
24
112
32
155
2.10
3.71
5.5
4.0
—
—
—
0
0
18
67
2.72
3.67
3.4
2.3
—
—
—
0
0
72
455
1.63
3.62
2.7
2.4
3.4
8.5
ug/l
4.03
66
408
32
157
2.08
3.60
1.6
3.9
31.3
50.1
mg/l
0.49
26
132
153
1147
1.40
3.42
3.8
3.4
56.3
474.6
ng/l
2.94
101
792
25
116
2.19
3.25
3.1
3.1
2.7
2.3
mmol/l
0.28
18
82
36
192
1.91
3.24
1.2
1.2
—
—
—
0
0
27
130
2.11
3.21
1.1
1.6
111.6
110.4
u/ml
—
5
26
48
283
1.74
3.15
10.4
16.1
—
—
—
0
0
35
612
0.55
3.01
1.2
1.4
—
—
—
0
0
9
21
4.32
3.00
1.1
1.0
178.8
200.4
iu/ml
—
9
21
9
21
4.32
3.00
1.7
2.0
—
—
—
0
0
66
432
1.57
2.92
1.5
1.4
—
—
—
0
0
12
41
2.95
2.86
1.2
1.2
—
—
—
0
0
218
1776
1.30
2.80
1.8
1.6
1.5
1.4
mmol/l
1.12
192
1512
17
72
2.39
2.73
1.9
2.6
—
—
—
0
0
19
86
2.24
2.65
1.3
1.4
65.2
60.9
mmol/l
0.13
11
74
7
15
4.69
2.60
2.1
2.1
—
—
—
0
0
7
16
4.40
2.48
1.4
2.4
—
—
—
0
0
122
933
1.36
2.43
1.6
1.4
—
—
—
0
0
69
477
1.48
2.41
1.3
1.3
28.1
28.6
iu/l
0.05
64
401
7
17
4.14
2.36
1.4
1.3
—
—
—
0
0
62
422
1.50
2.34
2.9
2.7
167.5
153.9
ng/l
0.08
54
387
124
963
1.33
2.24
2.0
2.3
29.8
29.7
s
0.06
116
930
0
62
0.00
2.23
0.0
10.8
—
0.6
—
0
57
74
1014
0.71
2.20
1.3
1.4
—
—
—
0
0
78
565
1.42
2.16
1.1
1.1
—
—
—
0
0
12
49
2.47
2.11
1.2
1.1
—
—
—
0
0
33
199
1.68
2.08
1.1
1.2
—
—
—
0
0
15
69
2.19
2.05
1.9
2.3
33.9
31.9
pg
1.08
15
69
15
70
2.16
1.99
2.3
2.3
—
—
—
0
0
20
105
1.93
1.96
1.6
2.5
—
—
—
0
0
110
857
1.32
1.96
1.7
1.7
—
—
—
0
0
5
11
4.56
1.94
1.0
1.2
—
—
—
0
0
210
1781
1.23
1.89
4.1
4.0
8.5
9.1
mg/mmol
0.05
151
1153
14
65
2.17
1.88
1.1
1.1
—
—
titre
—
0
0
25
144
1.76
1.86
4.2
3.3
23.2
23.8
mg/l
0.04
18
90
10
40
2.52
1.84
1.1
1.0
1909.6
1784.1
miu/ml
—
10
40
6
17
3.55
1.84
1.0
1.1
—
—
—
0
0
7
23
3.06
1.80
1.1
1.1
—
—
—
0
0
16
84
1.92
1.60
1.6
1.4
—
—
—
0
0
16
84
1.92
1.60
1.6
1.4
—
—
—
0
0
16
84
1.92
1.60
1.6
1.4
—
—
—
0
0
16
84
1.92
1.60
1.6
1.4
—
—
—
0
0
20
114
1.77
1.57
1.4
2.1
—
—
—
0
0
5
15
3.35
1.52
1.6
1.1
—
—
—
0
0
24
146
1.66
1.52
1.1
1.8
—
—
—
0
0
0
44
0.00
1.51
0.0
1.8
—
150.4
—
0
38
10
45
2.24
1.46
6.3
7.0
—
—
—
0
0
195
1686
1.20
1.44
3.2
3.2
971.9
399.0
mg/l
0.54
136
1078
12
59
2.05
1.44
4.6
3.6
—
—
—
0
0
9
40
2.26
1.40
1.1
1.1
—
—
—
0
0
9
40
2.26
1.40
1.1
1.2
—
—
—
0
0
9
40
2.26
1.40
1.2
1.3
—
—
—
0
0
6
23
2.62
1.37
1.7
1.7
—
—
—
0
0
11
54
2.05
1.33
1.5
1.3
—
69.0
—
0
6
216
1900
1.18
1.32
3.3
3.1
7.9
8.0
mmol/l
0.09
194
1634
6
24
2.51
1.30
1.5
1.1
—
—
—
0
0
5
18
2.79
1.28
1.4
1.8
—
—
—
0
0
41
296
1.40
1.24
1.3
1.3
249.3
229.5
miu/ml
0.11
19
155
75
595
1.28
1.23
1.5
1.4
—
—
—
0
0
10
188
0.53
1.21
1.0
1.3
—
—
—
0
0
6
26
2.32
1.19
1.7
4.0
—
—
—
0
0
8
38
2.12
1.18
1.1
1.2
—
—
—
0
0
29
198
1.48
1.18
1.6
2.1
2.3
5.4
iu/l
3.03
14
79
10
50
2.01
1.16
1.3
1.3
71.1
67.8
pmol/l
—
5
19
64
506
1.29
1.10
2.0
2.1
12.3
13.0
nmol/l
0.35
57
453
36
261
1.40
1.09
2.9
3.5
—
—
—
0
0
8
41
1.96
1.09
1.0
1.2
—
—
—
0
0
22
145
1.53
1.06
2.5
2.3
53.7
152.4
ug/min
1.27
12
88
43
565
0.75
1.06
1.8
1.7
—
—
—
0
0
7
34
2.07
1.03
1.1
2.0
—
—
—
0
0
11
61
1.81
0.98
1.2
1.4
1.5
1.3
promille
—
5
50
0
30
0.00
0.97
0.0
1.0
—
—
—
0
0
715
6949
1.15
0.88
4.1
3.8
5.9
5.8
mmol/l
0.52
671
6430
11
64
1.73
0.86
2.3
1.5
0.9
1.0
g/l
0.85
11
64
21
145
1.46
0.85
1.3
1.4
0.4
0.4
nmol/l
0.15
16
121
8
45
1.78
0.84
4.9
3.7
—
—
—
0
0
8
45
1.78
0.84
2.1
1.2
—
—
—
0
0
17
114
1.50
0.80
1.1
1.2
—
—
—
0
0
9
53
1.71
0.75
1.0
2.8
—
—
—
0
0
68
571
1.21
0.74
2.9
4.0
—
—
—
0
0
7
38
1.85
0.73
2.3
2.1
547.6
495.2
min
—
7
25
7
41
1.71
0.70
1.6
1.3
5.1
5.7
mmol/l
—
7
41
227
2096
1.11
0.69
1.5
1.5
—
—
—
0
0
18
128
1.41
0.66
1.6
1.8
—
—
—
0
0
742
7270
1.12
0.63
4.3
3.9
4.6
4.8
mmol/l
4.11
707
6840
21
156
1.35
0.61
1.0
1.1
—
—
—
0
0
21
156
1.35
0.61
1.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.8
—
17.9
—
0
22
6
35
1.72
0.57
1.2
1.3
—
—
—
0
0
93
1044
0.88
0.55
2.7
2.6
0.6
0.8
ug/l
1.07
56
617
27
214
1.27
0.53
1.6
1.6
33.2
36.9
nmol/l
0.67
27
209
16
117
1.37
0.52
1.6
1.2
6.4
3.8
u/ml
—
9
52
32
261
1.23
0.50
2.1
2.4
—
—
—
0
0
10
143
0.70
0.48
1.6
1.6
—
—
—
0
0
16
211
0.75
0.48
1.2
1.5
—
—
—
0
0
7
48
1.46
0.47
1.1
1.4
—
—
—
0
0
7
48
1.46
0.47
2.0
2.3
—
—
—
0
0
709
6966
1.09
0.44
3.9
3.5
1.4
1.3
mmol/l
3.67
669
6499
51
443
1.16
0.43
1.3
1.2
—
—
—
0
0
748
7371
1.09
0.42
4.6
4.2
2.7
2.9
mmol/l
5.46
710
6892
16
206
0.77
0.41
1.2
1.4
—
—
—
0
0
33
277
1.20
0.41
1.8
2.1
20.0
21.0
s
0.83
28
245
5
33
1.52
0.41
1.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
11
79
1.40
0.41
2.7
2.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
2.7
—
0
17
16
205
0.78
0.40
1.2
1.4
—
—
—
0
0
10
71
1.41
0.39
1.0
1.1
—
—
—
0
0
734
7237
1.08
0.37
4.2
3.8
1.5
1.5
mmol/l
0.74
694
6772
34
291
1.18
0.36
1.4
2.1
—
—
—
0
0
9
71
1.27
0.36
1.1
1.9
—
—
—
0
0
6
42
1.43
0.35
1.2
1.1
—
—
—
0
0
292
3032
0.95
0.33
2.9
2.5
—
—
—
0
0
27
229
1.18
0.32
13.4
7.7
—
—
—
0
0
21
174
1.21
0.31
1.1
1.1
—
—
—
0
0
7
53
1.32
0.31
1.1
1.3
—
—
—
0
0
12
94
1.28
0.28
1.2
1.7
—
—
—
0
0
77
712
1.09
0.27
1.4
1.4
—
—
—
0
0
13
104
1.25
0.26
1.1
1.2
—
—
—
0
0
25
216
1.16
0.25
3.0
3.7
0.2
0.3
g/l
1.01
13
94
9
74
1.22
0.25
1.3
2.1
—
—
—
0
0
11
87
1.27
0.24
1.1
1.4
—
—
nmol/l
—
0
0
63
581
1.09
0.24
1.2
1.2
39.6
136.0
iu/ml
7.39
26
239
42
381
1.11
0.22
1.6
2.0
—
—
—
0
0
42
382
1.10
0.21
1.6
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
12
98
1.23
0.21
2.3
2.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
42
383
1.10
0.21
1.6
1.9
—
—
—
0
0
42
384
1.10
0.20
1.6
2.0
—
—
—
0
0
181
1749
1.04
0.18
4.5
4.2
2.5
2.5
ug/l
0.05
165
1590
5
66
0.76
0.17
1.2
1.7
—
—
—
0
0
38
350
1.09
0.16
1.6
2.0
—
—
—
0
0
11
92
1.20
0.16
1.4
1.3
—
—
—
0
0
8
72
1.11
0.16
1.4
1.1
—
—
—
0
0
88
841
1.05
0.15
1.6
1.8
—
—
—
0
0
11
93
1.19
0.14
1.2
1.3
—
—
—
0
0
14
160
0.87
0.14
1.5
1.2
—
—
—
0
0
28
305
0.92
0.14
2.1
1.7
—
—
—
0
0
6
54
1.11
0.09
1.2
1.1
—
—
—
0
0
6
54
1.11
0.09
1.3
1.2
34.3
34.8
g/l
—
6
49
22
204
1.08
0.08
2.2
2.7
—
—
—
0
0
6
72
0.83
0.07
1.0
1.5
—
—
—
0
0
28
264
1.06
0.07
2.1
2.3
—
—
—
0
0
13
143
0.91
0.07
1.1
1.1
—
2.4
u/ml
—
0
36
14
128
1.10
0.06
1.1
1.0
—
3.6
u/ml
—
0
44
11
99
1.11
0.06
1.1
1.7
—
—
—
0
0
9
104
0.86
0.06
1.0
1.0
—
0.4
—
0
23
38
366
1.04
0.05
1.1
1.1
—
—
—
0
0
17
162
1.05
0.02
1.6
2.7
—
—
—
0
0
13
136
0.96
0.00
1.7
3.4
—
—
—
0
0
12
119
1.01
0.00
1.1
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
5.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
0
9
0.00
0.00
0.0
7.0
—
—
—
0
0
12
120
1.00
0.00
1.3
1.5
2.6
4.0
ug/l
0.63
12
104
6
65
0.92
0.00
1.3
1.1
—
—
—
0
0
5
51
0.98
0.00
1.0
2.4
—
2.1
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
0.00
1.4
2.1
8.3
12.1
%
—
5
51
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
37.8
—
0
6
0
9
0.00
0.00
0.0
3.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
14.9
—
0
8
0
6
0.00
0.00
0.0
2.8
—
387.5
—
0
6

Mortality – FinRegistry

Association

Association between endpoint M13_ENTEROARTHR and mortality.

Females

Parameter HR [95% CI] p-value
M13_ENTEROARTHR 1.395 [1.15, 1.69] < 0.001
Birth year 0.997 [0.99, 1.01] 0.455

During the follow-up period (1.1.1998 — 31.12.2019), 127 out of 1603 females with M13_ENTEROARTHR died.

Males

Parameter HR [95% CI] p-value
M13_ENTEROARTHR 1.313 [1.08, 1.59] 0.006
Birth year 0.987 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 154 out of 1230 males with M13_ENTEROARTHR died.

Mortality risk

Mortality risk for people of age

years, who have M13_ENTEROARTHR.

N-year risk Females Males
1 0.16% 0.23%
5 0.878% 1.55%
10 2.166% 3.741%
15 4.3% 6.91%
20 7.2% 11.991%

Relationships between endpoints

Index endpoint: M13_ENTEROARTHR – Enteropathic arthropathies

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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