Malignant Pancreatic Neoplasm: A primary or metastatic malignant tumor involving the pancreas. Representative examples include carcinoma and lymphoma. -- 2003
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
857 |
4. Check minimum number of eventsNone |
857 |
5. Include endpointsNone |
857 |
6. Filter based on genotype QC (FinnGen only) |
857 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D13
- Name in latin
- Neoplasma benignum pancreatis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Pancreas
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Pancreas
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4049 | 2363 | 1645 |
| Only index persons | 3590 | 2126 | 1464 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.07 | 0.05 |
| Only index persons | 0.07 | 0.08 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 69.61 | 70.03 | 69.18 |
| Only index persons | 69.51 | 69.68 | 69.25 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 857 | 490 | 367 |
| Unadjusted period prevalence (%) | 0.16 | 0.17 | 0.16 |
| Median age at first event (years) | 69.48 | 68.35 | 71.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 715
- Matched controls
- 7151
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
4503599627370496.0
323.0
704
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
69.7
302.3
343
93
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
28.9
89.7
123
51
K86.2
ICD-10 Finland
Cyst of pancreas
65.8
88.8
102
18
A09AA02
ATC
multienzymes (lipase, protease etc.)
24.0
82.2
119
59
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
33.8
74.0
97
33
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
16.4
67.7
112
80
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
93.8
62.1
68
8
JLC30
NOMESCO Finland
Pancreatoduodenectomy
50.7
57.6
69
15
JLC10
NOMESCO Finland
Distal pancreatectomy
128.3
55.7
59
5
WX302
NOMESCO Finland
Thoracal epidural anesthesy
7.8
48.1
117
174
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
32.7
48.0
63
21
JLC11
NOMESCO Finland
Laparoscopic distal pancreatectomy
+∞
41.0
39
*
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
11.2
39.8
77
76
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
22.4
38.5
56
27
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
44.6
37.6
46
11
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
17.2
35.2
56
35
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
19.9
34.5
52
28
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
7.5
33.5
82
121
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.7
32.8
329
1722
UJK02
NOMESCO Finland
ERCP
8.2
28.4
65
86
WZC30
NOMESCO Finland
Teaching
3.2
28.0
168
621
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.6
26.7
98
237
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.6
25.7
94
227
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
60.3
25.2
29
5
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.9
25.0
179
740
Z71.8
ICD-10 Finland
Other specified counselling
2.6
24.7
217
1015
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.3
24.0
136
476
JN3AD
NOMESCO Finland
Abdominal CT examination
3.9
22.6
99
282
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
10.1
22.6
45
47
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
22.1
283
1593
D13.7
ICD-10 Finland
Benign neoplasm: Endocrine pancreas
82.7
21.8
24
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.4
21.0
108
351
ZX120
NOMESCO Finland
Intravenous
3.3
20.2
112
385
K83.0
ICD-10 Finland
Cholangitis
11.8
20.2
37
33
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
11.4
19.9
37
34
TPH07
NOMESCO Finland
Cathetrisation of artery
3.1
19.5
121
447
K83.1
ICD-10 Finland
Obstruction of bile duct
9.5
19.1
39
43
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.0
19.1
79
214
B01AB10
ATC
tinzaparin; parenteral
3.6
18.8
88
265
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
11.8
18.7
34
30
JMA10
NOMESCO Finland
Transabdominal total splenectomy
20.0
18.3
27
14
N02BE01
ATC
paracetamol; systemic, rectal
2.7
17.1
645
5526
K86.3
ICD-10 Finland
Pseudocyst of pancreas
26.3
17.0
23
9
WX402
NOMESCO Finland
General anaesthesia
2.5
16.8
146
660
R4190
NOMESCO Finland
Nutritional therapy
6.2
16.3
44
75
UJF32
NOMESCO Finland
Coloscopy
2.1
16.2
239
1388
B01AB05
ATC
enoxaparin; parenteral
2.0
15.5
269
1660
RD211
NOMESCO Finland
NA
4.1
15.5
62
163
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
11.6
15.4
28
25
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
7.9
15.0
34
45
K85.8
ICD-10 Finland
Other acute pancreatitis
18.9
14.8
22
12
8240/3-C25.9
ICD-O-3
Neuroendocrine tumor, NOS, of pancreas, NOS
+∞
14.6
14
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
14.6
133
615
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
10.4
14.6
28
28
A02BC02
ATC
pantoprazole; systemic
1.9
14.5
502
3936
K86.1
ICD-10 Finland
Other chronic pancreatitis
12.9
14.5
25
20
K86.8
ICD-10 Finland
Other specified diseases of pancreas
18.0
13.9
21
12
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
12.4
13.7
24
20
C25.4
ICD-10 Finland
Malignant neoplasm: Endocrine pancreas
76.6
13.6
15
*
JMA11
NOMESCO Finland
Laparoscopic total splenectomy
142.5
13.5
14
*
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
6.6
13.4
34
54
JN4CD
NOMESCO Finland
Very extensive body CT
3.7
13.2
59
171
130
Kela drug reimbursment
Malignant tumour
2.7
13.2
94
375
XX3DW
NOMESCO Finland
Time consuming IT work
2.5
12.9
108
475
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
7.4
12.9
30
42
JAH01
NOMESCO Finland
Laparoscopy
3.9
12.7
53
145
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
15.8
12.7
20
13
R50.9
ICD-10 Finland
Fever, unspecified
2.3
12.7
123
582
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
20.5
12.5
18
9
R4110
NOMESCO Finland
Physiotherapy
1.9
12.1
220
1357
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
47.5
11.9
14
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
11.0
171
989
8140/3-C25.9
ICD-O-3
Adenocarcinoma, NOS, of pancreas, NOS
14.5
10.5
17
12
J01MA12
ATC
levofloxacin; systemic
2.0
10.4
158
906
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
10.2
135
730
103
Kela drug reimbursment
Diabetes, insulin-treated
1.8
10.1
217
1400
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
10.1
172
1026
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
10.0
198
1242
D13.9
ICD-10 Finland
Benign neoplasm: Ill-defined sites within the digestive system
40.6
10.0
12
*
N02AX02
ATC
tramadol; systemic, rectal
1.7
9.9
324
2365
J01MA02
ATC
ciprofloxacin; systemic
1.7
9.8
293
2084
Z00.0
ICD-10 Finland
General medical examination
2.0
9.8
143
805
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
9.7
202
1288
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
5.6
9.6
27
50
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
6.1
9.6
25
42
C25.2
ICD-10 Finland
Malignant neoplasm: Tail of pancreas
15.3
9.5
15
10
UJK12
NOMESCO Finland
Peroral cholangioscopy
30.4
9.4
12
*
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.2
9.4
102
508
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
8.8
9.3
19
22
JAH00
NOMESCO Finland
Laparotomy
4.4
9.2
32
75
N02AA05
ATC
oxycodone; systemic
2.0
9.1
127
699
C25.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of pancreas
18.9
9.0
13
7
JLB28
NOMESCO Finland
Endoscopic internal drainage of pancreatic duct
24.3
8.9
12
5
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
8.8
156
937
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
8.8
160
971
A05AA02
ATC
ursodeoxycholic acid; oral
6.3
8.7
22
36
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
8.6
93
463
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
11.7
8.6
15
13
K85
ICD-10 Finland
Acute pancreatitis
5.0
8.6
26
53
R93.3
ICD-10 Finland
Abnormal findings on diagnostic imaging of other parts of digestive tract
16.5
8.6
13
8
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
8.5
213
1425
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
27.9
8.5
11
*
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
20.3
8.5
12
6
UJF92
NOMESCO Finland
Capsular endoscopy
5.4
8.4
24
46
JL5AM
NOMESCO Finland
Bile and pancreas ducts simple MRI examination with 3 Tesla magnet
+∞
8.3
8
*
T90
ICPC
Diabetes non-insulin dependent
1.7
8.3
189
1230
J01DB01
ATC
cefalexin; oral
1.7
8.2
566
4933
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
17.4
8.1
12
7
C25.1
ICD-10 Finland
Malignant neoplasm: Body of pancreas
13.2
7.9
13
10
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.4
7.8
63
272
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
7.8
93
482
R53
ICD-10 Finland
Malaise and fatigue
1.8
7.7
153
951
L01BC06
ATC
capecitabine; oral
3.2
7.7
39
127
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
7.7
168
1075
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.6
7.6
53
212
A02BC05
ATC
esomeprazole; systemic
1.6
7.4
300
2261
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
13.5
7.4
12
9
-1
NOMESCO Finland
NA
1.6
7.3
209
1441
SPAT1252
SPAT
Overall medication plan or its review
2.3
7.2
65
297
A10AE04
ATC
insulin glargine; parenteral
2.2
7.2
76
372
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.1
7.1
80
403
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
3.4
7.1
32
96
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.8
7.1
45
169
C07AB07
ATC
bisoprolol; oral
1.5
7.1
363
2882
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
4.6
6.8
22
49
K59.09
ICD-10 Finland
Constipation, unspecified
2.4
6.8
54
232
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
6.2
6.8
17
28
JL1AT
NOMESCO Finland
Biopsy of pancreas with ultrasound guidance
40.4
6.8
8
*
Z25.1
ICD-10 Finland
Need for immunization against influenza
2.5
6.7
51
216
JN4BD
NOMESCO Finland
Extensive body CT
1.9
6.6
100
568
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
12.4
6.6
11
9
A10BA02
ATC
metformin; oral
1.6
6.5
207
1465
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.5
6.4
48
198
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
6.4
237
1730
JLC40
NOMESCO Finland
Total pancreatoduodenectomy
70.4
6.4
7
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.9
6.3
24
63
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2.6
6.3
42
165
C25
ICD-10 Finland
Malignant neoplasm of pancreas
+∞
6.3
6
*
158
Kela drug reimbursment
Everolimus
+∞
6.3
6
*
JLB35
NOMESCO Finland
Transduodenal endoscopic extraction of foreign body from pancreatic duct
+∞
6.3
6
*
8500/3-C25.0
ICD-O-3
Infiltrating duct carcinoma, NOS, of head of pancreas
26.9
6.2
8
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
6.2
121
747
SPAT1262
SPAT
Handing over of treatment supplies
1.7
6.1
146
952
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
6.1
99
576
8000/3-C25.9
ICD-O-3
Neoplasm, malignant of pancreas, NOS
10.1
6.0
11
11
D76
ICPC
Malignant neoplasm pancreas
10.1
6.0
11
11
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
6.0
66
332
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
341
167
33.25
307.65
3.3
3.7
41.1
2199.6
u/ml
0.83
315
159
305
329
13.84
272.42
4.5
3.3
76.9
4332.6
u/ml
0.79
273
281
433
892
8.79
226.27
3.6
4.2
2.8
25.9
ug/l
1.79
363
741
317
753
6.09
134.62
2.9
2.1
0.2
0.2
g/l
6.59
309
707
172
248
8.43
117.84
1.6
1.5
218.6
280.5
ug/g
2.70
127
147
570
2408
5.08
116.59
4.1
2.4
64.0
57.4
u/l
0.78
552
2203
305
846
5.04
105.31
4.1
2.8
6.3
8.4
umol/l
1.63
275
740
55
14
41.91
90.63
4.2
2.2
1917.7
5718.3
u/l
0.44
55
14
714
4052
5.57
88.96
10.5
6.4
11.0
11.5
umol/l
0.56
700
3839
246
683
4.65
82.76
4.9
2.3
244.6
35.9
u/l
1.34
222
570
67
7
103.72
61.83
3.2
2.7
68.2
39.9
pmol/l
—
54
7
597
3432
3.44
61.69
8.2
4.8
34.4
35.1
g/l
2.45
584
3193
792
5859
5.64
48.11
13.9
7.7
86.0
79.1
u/l
2.89
779
5464
667
4514
3.15
44.28
6.8
4.9
7.0
6.8
mmol/l
2.02
652
4262
411
2333
2.46
36.24
4.4
3.3
34.1
32.9
u/l
0.25
400
2208
173
667
3.00
32.92
5.1
3.5
1.2
1.2
mmol/l
0.07
165
584
375
2199
2.25
28.87
4.1
3.2
0.5
0.5
e6/l
0.03
313
1689
448
2841
2.21
28.21
4.3
3.3
—
—
—
0
0
595
4263
2.29
27.22
11.9
9.2
4.5
4.1
e9/l
2.32
546
3743
562
3955
2.22
26.55
8.8
6.9
1.2
1.2
mmol/l
0.22
468
3348
245
1241
2.36
26.26
2.5
2.0
30.2
29.7
s
0.64
240
1199
43
69
6.51
25.93
1.7
1.4
—
—
—
0
0
213
1030
2.42
25.23
6.5
5.5
1.0
1.0
mmol/l
0.82
206
941
300
1679
2.21
25.16
3.4
2.6
5.5
5.2
e6/l
0.16
262
1493
245
1276
2.29
24.36
3.5
3.3
0.8
0.8
mmol/l
0.62
232
1185
508
3516
2.09
23.98
5.8
4.1
—
—
—
0
0
728
5843
2.63
23.46
32.1
19.6
14.0
13.8
%
3.19
722
5718
334
1997
2.10
23.25
5.1
4.2
0.0
0.0
estimate
0.50
182
648
515
3638
2.04
22.31
7.9
6.0
1.2
1.2
mmol/l
1.24
498
3275
70
200
3.72
21.33
1.2
1.2
—
—
—
0
0
43
95
4.71
18.39
1.7
1.3
0.6
0.6
nmol/l
0.76
38
89
129
570
2.49
18.18
3.2
2.8
10.5
10.6
g/l
0.12
112
518
497
3634
1.88
17.61
5.6
5.3
0.0
0.0
estimate
0.00
187
676
495
3621
1.87
17.45
4.6
3.9
0.0
0.0
estimate
0.00
183
681
225
1271
2.04
17.39
3.4
3.0
2.2
2.2
e6/l
0.02
136
716
207
1144
2.07
16.93
3.5
2.5
2.3
2.3
g/l
0.17
195
1060
499
3683
1.85
16.84
4.6
3.9
0.0
0.0
estimate
0.00
185
658
68
224
3.21
16.61
2.3
1.6
—
—
—
0
0
196
1078
2.06
16.17
3.7
2.5
22.7
22.2
%
0.15
180
917
433
3088
1.81
16.08
2.8
2.2
79.4
78.7
nmol/l
0.22
411
2701
629
5051
1.92
15.65
5.8
4.7
44.0
3156.3
e6/l
—
6
87
17
17
10.18
14.95
1.1
1.1
—
—
—
0
0
17
17
10.18
14.95
1.1
1.1
—
—
—
0
0
212
1242
1.94
14.44
3.5
2.5
12.4
12.7
umol/l
0.23
200
1145
806
7197
3.01
14.20
27.7
15.7
29.2
24.9
mg/l
2.77
715
5767
389
2785
1.73
13.45
4.7
4.2
—
—
—
0
0
156
844
2.04
13.24
4.6
3.4
—
—
—
0
0
108
509
2.28
13.02
8.4
9.1
94.7
94.0
%
0.67
108
504
414
3050
1.69
12.63
4.3
3.9
40.0
48.6
ng/l
0.19
309
2288
131
699
2.03
11.47
8.5
7.3
9.8
10.2
mmol/l
0.33
123
664
348
2504
1.66
11.23
3.4
3.2
6.5
7.1
mmol/l
1.88
305
2052
557
4514
1.67
11.17
4.6
3.2
73.7
52.5
u/l
2.36
532
4150
770
6883
2.17
10.87
26.8
14.8
75.7
76.1
ml/min/173m2
0.27
725
5681
239
1569
1.73
10.82
4.0
3.2
2.5
2.5
mmol/l
1.33
217
1389
115
607
2.03
10.34
2.7
2.8
68.7
61.4
ml/min/173m2
1.18
57
259
353
2601
1.61
10.05
4.3
4.0
6.6
8.4
mg/mmol
0.73
241
1606
28
74
3.88
9.56
1.3
1.2
62.4
49.5
u/l
0.79
23
53
646
5534
1.68
9.55
5.5
4.3
15.2
13.4
mm/h
1.86
620
5065
400
3063
1.57
9.51
4.3
2.8
132.5
143.4
ug/l
0.50
383
2782
35
110
3.27
9.27
1.7
2.1
32.1
32.4
pg
0.15
35
110
363
2730
1.57
9.26
4.3
3.6
2.4
2.4
mmol/l
0.02
343
2353
39
134
3.00
8.92
2.9
2.8
4.5
4.5
e9/l
0.03
39
134
43
1026
0.39
8.88
4.6
4.8
34.8
32.6
%
0.57
35
665
40
140
2.95
8.86
3.3
3.1
57.0
59.4
%
0.64
40
140
16
28
5.80
8.83
1.5
1.3
29.3
30.5
umol/l
0.15
16
28
236
1619
1.63
8.77
2.0
1.7
1.5
1.3
mg/l
0.36
184
1280
50
200
2.59
8.62
3.3
2.6
3.9
3.6
g/l
0.55
50
190
104
568
1.95
8.45
1.7
1.6
—
—
—
0
0
169
1073
1.72
8.41
24.3
28.1
1.6
1.3
inr
1.09
17
139
280
2020
1.57
8.37
2.8
2.2
3.4
3.1
mg/l
0.92
253
1719
48
192
2.59
8.29
1.8
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
61
276
2.30
8.08
2.8
2.5
0.2
0.4
u/ml
6.62
38
156
26
75
3.54
7.87
1.3
1.3
—
—
—
0
0
275
2013
1.54
7.56
3.7
2.8
2081.9
8109.5
umol/l
2.28
252
1714
814
7618
2.37
7.36
31.0
18.8
4.0
4.0
mmol/l
0.57
809
7402
65
315
2.15
7.31
2.5
2.7
2.9
3.1
g/l
1.00
43
249
34
122
2.86
7.24
1.3
1.3
—
—
—
0
0
148
942
1.69
7.23
2.0
1.9
—
—
—
0
0
49
212
2.39
7.20
1.3
1.6
—
—
—
0
0
193
1320
1.60
7.09
2.0
1.9
—
—
—
0
0
198
1364
1.59
7.05
3.2
2.8
1.3
1.1
e6/l
0.30
107
803
61
293
2.16
7.02
2.7
2.9
0.9
1.3
g/l
0.45
53
257
41
165
2.56
7.02
1.4
1.3
—
—
—
0
0
753
6885
1.77
6.96
7.9
6.4
42.1
40.5
mmol/mol
4.33
736
6318
146
940
1.67
6.81
2.0
1.8
—
—
—
0
0
55
259
2.20
6.66
2.9
2.8
0.0
0.0
g/l
0.06
49
238
19
50
3.86
6.56
1.0
1.2
—
—
—
0
0
117
717
1.73
6.54
3.0
3.0
66.4
66.3
g/l
0.05
111
645
20
55
3.70
6.50
1.5
1.1
—
—
—
0
0
115
703
1.73
6.49
7.2
6.9
1.3
1.4
mmol/l
0.75
106
673
146
965
1.62
6.12
8.0
7.2
0.8
1.3
mmol/l
1.02
119
748
65
340
1.99
6.00
2.5
2.6
3.7
3.7
g/l
0.02
43
246
141
930
1.62
5.95
4.3
4.2
231.2
253.9
u/l
0.89
134
878
65
341
1.98
5.95
2.5
2.6
—
—
—
0
0
65
341
1.98
5.95
2.5
2.6
7.4
7.4
g/l
0.00
44
255
36
149
2.48
5.85
6.2
6.5
256.7
183.6
iu/ml
—
6
19
38
162
2.41
5.81
3.1
2.7
15.9
15.8
%
0.07
19
82
89
522
1.79
5.79
9.5
8.7
1.2
1.3
%
1.02
89
517
18
50
3.66
5.78
1.0
1.2
—
—
—
0
0
87
518
1.76
5.38
9.8
8.8
0.7
0.7
%
0.02
87
513
74
422
1.82
5.29
3.5
2.8
0.1
0.2
e6/l
3.44
74
413
28
108
2.65
5.27
1.5
1.4
91.2
108.4
u/ml
—
5
16
210
1555
1.46
5.18
4.1
4.1
245.3
360.9
ng/l
0.33
168
1287
304
2412
1.40
5.12
2.3
2.2
133.6
222.0
u/l
1.93
294
2260
623
5588
1.42
4.91
4.4
3.9
15.1
15.0
pmol/l
0.61
587
4985
27
107
2.57
4.83
1.2
1.2
322.7
342.6
u/ml
0.09
21
60
202
1505
1.45
4.79
1.3
1.2
1.0
1.8
u/ml
1.09
83
381
28
114
2.51
4.75
1.1
1.2
—
—
—
0
0
229
1751
1.42
4.70
1.9
1.7
451.9
15674193.1
pmol/l
1.31
193
1410
317
2565
1.37
4.65
2.8
3.1
1323.9
1384.0
ng/l
0.11
290
2198
52
278
1.93
4.56
2.9
4.0
1.6
1.9
ratio
0.15
14
22
66
382
1.79
4.52
3.0
3.0
4.5
4.5
pmol/l
0.14
60
329
51
273
1.92
4.46
2.7
2.6
37.9
37.3
g/l
0.40
43
234
52
281
1.91
4.42
3.0
4.1
29.1
44.4
mg/l
0.75
44
228
52
281
1.91
4.42
3.0
4.0
36.5
78.6
mg/l
1.14
44
226
238
1852
1.39
4.38
3.3
2.4
—
—
—
0
0
822
7894
2.01
4.11
39.9
23.6
129.6
133.7
g/l
12.89
817
7755
434
3741
1.32
4.00
2.7
2.5
—
—
—
0
0
13
38
3.46
3.91
1.6
1.4
0.9
1.0
nmol/l
0.33
13
29
23
94
2.49
3.91
1.2
1.1
28.2
111.3
iu/ml
—
5
15
12
34
3.57
3.77
4.2
4.2
—
—
—
0
0
75
474
1.64
3.77
1.6
1.5
—
—
—
0
0
717
6697
1.43
3.69
5.3
4.9
1.9
2.2
mu/l
0.77
682
6024
30
143
2.14
3.63
1.6
1.8
52.5
43.4
nmol/l
0.29
30
134
46
258
1.83
3.54
2.3
1.6
116.7
102.5
titre
—
6
8
77
500
1.59
3.49
1.7
1.7
—
—
—
0
0
26
120
2.20
3.41
1.2
1.1
—
—
—
0
0
12
37
3.28
3.35
1.2
1.2
—
—
—
0
0
388
3353
1.29
3.29
2.4
2.1
89.2
95.3
pmol/l
2.28
240
1675
759
7199
1.47
3.27
5.6
5.0
6.2
6.0
mmol/l
3.34
726
6462
20
84
2.41
3.24
1.9
2.4
—
—
—
0
0
53
319
1.71
3.23
2.6
2.7
9.7
10.3
g/l
0.56
43
273
14
49
2.89
3.20
1.1
1.2
9.8
11.7
mmol/l
—
9
12
53
320
1.70
3.20
1.7
2.0
40.0
39.1
u/l
0.13
48
278
253
2075
1.31
3.16
1.7
1.7
1.4
1.4
mmol/l
0.74
218
1720
43
246
1.79
3.13
2.9
2.8
0.0
0.0
g/l
0.00
38
225
93
652
1.48
3.00
5.9
3.8
83.9
92.2
ng/l
0.44
78
565
59
376
1.61
2.92
12.5
3.7
23.9
24.3
mmol/l
0.45
51
336
30
157
1.94
2.88
1.4
1.3
37.9
30.7
iu/l
0.44
23
138
23
109
2.14
2.86
10.4
5.6
11.7
12.3
mg/l
0.29
23
99
13
47
2.79
2.82
1.4
1.6
—
—
—
0
0
70
1010
0.67
2.73
15.6
7.8
—
—
—
0
0
38
219
1.77
2.73
1.2
1.5
0.2
0.2
g/l
0.03
38
209
14
54
2.62
2.71
1.0
1.0
292.9
296.4
mg/l
0.06
14
44
104
762
1.42
2.67
6.2
3.6
1.4
2.0
mmol/l
0.86
89
599
15
61
2.49
2.63
1.4
1.8
—
—
—
0
0
14
55
2.57
2.62
1.8
1.1
98.0
92.0
titre
—
5
10
242
2028
1.27
2.49
1.7
1.5
21.9
20.8
nmol/l
0.52
226
1689
22
109
2.05
2.48
2.0
1.7
—
—
—
0
0
21
103
2.06
2.43
1.7
2.0
91.3
89.5
%
1.49
21
103
45
282
1.63
2.42
2.3
3.0
—
—
—
0
0
6
12
5.03
2.40
6.5
7.0
4.9
6.1
mmol/l
—
6
12
5
8
6.28
2.37
3.8
6.0
—
—
—
0
0
12
46
2.63
2.36
1.3
1.6
—
—
—
0
0
18
84
2.17
2.36
2.2
1.8
—
—
—
0
0
28
157
1.81
2.24
1.4
1.4
—
—
—
0
0
28
157
1.81
2.24
1.4
1.4
—
—
—
0
0
37
227
1.66
2.18
1.3
1.5
1.1
1.2
g/l
0.30
37
217
7
19
3.71
2.15
1.0
1.2
88.6
138.2
iu/ml
—
7
19
91
679
1.38
2.14
1.6
1.7
1.7
1.5
%
0.63
74
564
39
244
1.63
2.14
1.2
1.2
—
—
—
0
0
9
31
2.92
2.07
2.6
1.7
1.4
7.5
nmol/l
—
9
25
151
1220
1.29
2.07
1.4
1.3
31.5
36.9
iu/ml
0.29
52
384
61
427
1.46
2.04
9.4
9.6
24.0
24.5
mmol/l
0.81
56
399
31
185
1.70
2.03
1.7
1.8
—
—
—
0
0
36
224
1.63
2.02
1.3
1.6
—
—
—
0
0
37
232
1.62
2.02
1.3
1.2
—
—
—
0
0
9
32
2.83
2.00
1.0
1.0
—
—
—
0
0
6
16
3.77
1.93
1.0
1.0
—
—
—
0
0
117
924
1.31
1.90
1.3
1.4
—
—
—
0
0
9
34
2.66
1.87
2.6
2.3
—
—
—
0
0
30
183
1.66
1.84
1.4
1.4
—
—
—
0
0
31
191
1.65
1.83
1.7
1.7
—
—
—
0
0
5
12
4.18
1.82
2.2
1.3
—
—
—
0
0
36
231
1.58
1.81
1.3
1.2
—
—
—
0
0
29
176
1.67
1.81
1.4
2.7
34.2
31.6
umol/l
0.14
21
144
12
53
2.28
1.81
1.1
1.2
—
—
—
0
0
24
138
1.76
1.81
1.9
1.8
—
—
—
0
0
8
30
2.68
1.72
1.3
1.1
—
65.2
%
—
0
5
7
161
0.43
1.68
1.0
1.1
—
—
—
0
0
12
55
2.20
1.68
1.0
1.2
—
—
—
0
0
33
212
1.58
1.67
1.5
1.6
0.4
0.1
iu/ml
—
10
41
759
7341
1.30
1.65
5.5
5.4
2.5
2.7
mmol/l
6.21
721
6670
55
396
1.42
1.63
1.9
1.9
1.4
1.5
g/l
0.55
48
348
22
129
1.72
1.58
1.3
1.5
—
—
—
0
0
46
325
1.44
1.52
1.0
1.0
—
—
—
0
0
24
146
1.66
1.52
1.7
1.6
—
—
—
0
0
601
6303
0.84
1.46
27.8
17.5
39.1
39.0
%
0.17
448
4097
12
59
2.05
1.44
1.3
1.5
—
—
—
0
0
10
46
2.19
1.40
1.3
1.4
—
—
—
0
0
10
46
2.19
1.40
1.3
1.4
—
—
—
0
0
14
75
1.88
1.35
1.5
1.7
15431.8
8253.8
u/l
—
6
18
0
37
0.00
1.34
0.0
1.2
—
—
—
0
0
0
40
0.00
1.33
0.0
2.6
—
—
—
0
0
712
6875
1.21
1.31
4.2
4.2
1.3
1.3
mmol/l
1.48
666
6184
17
99
1.73
1.28
1.6
1.6
—
—
—
0
0
174
1509
1.19
1.26
3.4
3.3
0.8
0.8
ug/l
0.10
124
1064
5
19
2.64
1.21
1.2
1.6
15.8
14.2
pmol/l
—
5
13
112
934
1.23
1.21
1.3
1.4
—
—
—
0
0
30
429
0.69
1.21
1.7
1.8
—
—
—
0
0
19
117
1.64
1.19
1.1
1.2
—
—
—
0
0
19
117
1.64
1.19
1.9
1.6
—
—
—
0
0
54
416
1.32
1.12
1.3
1.2
468.2
188.2
u/ml
0.35
48
374
52
399
1.32
1.11
1.2
1.2
74.9
137.6
iu/ml
1.53
20
153
24
160
1.51
1.10
1.7
1.6
4.2
5.7
iu/l
—
10
47
14
81
1.74
1.09
2.3
2.4
—
—
—
0
0
5
21
2.39
1.09
3.2
3.2
76.6
71.8
%
—
5
16
183
1616
1.17
1.08
4.7
4.4
1.0
1.0
kg/l
0.07
16
243
24
162
1.50
1.05
1.6
1.5
—
—
—
0
0
136
1175
1.19
1.04
1.4
1.3
9.9
13.3
u/ml
0.28
64
408
10
175
0.57
0.99
1.8
1.6
—
—
—
0
0
43
328
1.33
0.97
1.4
1.3
—
—
—
0
0
0
31
0.00
0.96
0.0
1.2
—
—
—
0
0
5
102
0.49
0.90
1.2
1.4
—
—
—
0
0
5
103
0.48
0.89
1.2
1.4
—
—
—
0
0
5
103
0.48
0.89
1.2
1.4
—
—
—
0
0
5
104
0.48
0.89
1.2
1.4
—
—
—
0
0
5
104
0.48
0.89
1.2
1.4
—
—
—
0
0
16
103
1.56
0.88
1.4
1.4
54.3
59.4
%
—
9
68
8
45
1.78
0.84
2.8
2.6
13.9
13.3
%
—
8
45
735
7180
1.17
0.84
5.0
4.8
4.4
4.6
mmol/l
4.52
696
6557
24
172
1.41
0.81
3.3
2.4
128.2
127.5
g/l
0.04
18
127
15
98
1.54
0.79
2.5
3.6
—
—
—
0
0
15
222
0.67
0.78
1.5
1.8
1.5
2.9
mg/l
—
10
169
5
100
0.50
0.77
3.0
4.5
310.0
364.6
umol/l
—
5
88
23
166
1.40
0.76
1.2
1.2
8.3
46.6
e6/l
0.62
16
129
5
24
2.09
0.74
1.2
1.3
—
—
—
0
0
5
24
2.09
0.74
1.2
1.1
—
—
—
0
0
17
117
1.46
0.72
1.4
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
41
1.71
0.70
1.0
1.2
—
—
—
0
0
11
169
0.65
0.69
1.4
1.4
—
—
—
0
0
84
727
1.17
0.67
2.6
2.6
4.9
6.3
ug/l
0.67
73
637
5
29
1.73
0.64
1.2
1.6
—
—
—
0
0
727
7128
1.13
0.63
4.7
4.7
1.5
1.5
mmol/l
0.62
686
6462
6
104
0.57
0.62
1.2
1.4
—
—
—
0
0
8
49
1.64
0.62
1.4
1.6
—
—
—
0
0
26
201
1.30
0.59
2.2
1.6
10618.4
17015.0
e6/l
0.71
19
146
8
53
1.51
0.58
1.0
1.1
—
—
—
0
0
8
53
1.51
0.58
1.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
26.7
—
0
17
8
54
1.49
0.57
1.0
1.1
—
—
—
0
0
8
54
1.49
0.57
1.0
1.1
—
—
—
0
0
8
54
1.49
0.57
1.0
1.1
—
—
—
0
0
174
1602
1.11
0.57
2.1
1.8
1317.1
1208.6
nmol/l
0.84
137
1182
8
55
1.46
0.56
2.9
1.5
0.8
1.0
g/l
—
8
55
10
65
1.54
0.55
1.0
1.1
—
—
—
0
0
275
2595
1.09
0.54
5.6
5.5
2.6
3.0
ug/l
0.45
248
2307
9
61
1.48
0.54
1.1
1.1
—
—
—
0
0
6
40
1.50
0.51
1.5
2.7
423.7
1281.8
u/ml
—
6
40
12
86
1.40
0.44
1.0
1.1
2.3
5.9
u/ml
—
6
41
5
33
1.52
0.41
1.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
6
42
1.43
0.35
1.0
1.1
—
—
—
0
0
6
47
1.28
0.32
1.2
1.0
—
—
—
0
0
7
52
1.35
0.31
1.0
1.4
—
50.0
—
0
8
7
55
1.27
0.30
1.0
1.5
—
275.0
—
0
6
12
94
1.28
0.28
1.1
1.3
—
—
—
0
0
41
366
1.13
0.27
1.6
1.8
—
—
—
0
0
12
95
1.27
0.26
1.8
1.4
31661.0
43538.8
e6/l
—
6
49
10
77
1.30
0.26
1.0
1.1
—
—
—
0
0
9
72
1.25
0.25
1.1
1.1
—
—
—
0
0
19
162
1.18
0.23
1.6
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
25.3
—
0
11
0
10
0.00
0.21
0.0
3.0
—
—
—
0
0
0
10
0.00
0.21
0.0
3.0
—
—
—
0
0
25
283
0.88
0.21
2.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
10
81
1.24
0.19
1.8
1.7
—
—
—
0
0
7
61
1.15
0.17
2.3
1.4
46.9
33.9
u/l
—
7
50
8
68
1.18
0.16
1.0
1.0
—
—
—
0
0
25
225
1.11
0.16
2.0
2.5
113.9
84.7
ug/min
0.20
15
134
9
79
1.14
0.15
1.1
1.1
—
—
—
0
0
9
81
1.11
0.15
1.8
1.2
8.3
7.3
mmol/l
—
9
54
26
237
1.10
0.14
2.1
1.8
—
—
—
0
0
5
47
1.06
0.09
2.4
3.6
—
—
—
0
0
6
58
1.03
0.08
1.0
1.3
—
—
—
0
0
5
63
0.79
0.08
1.0
1.6
—
27.1
—
0
9
7
64
1.09
0.08
1.1
1.2
9.9
11.9
u/l
—
7
56
29
307
0.94
0.08
1.9
1.9
—
—
—
0
0
8
78
1.03
0.07
1.1
1.6
—
—
—
0
0
8
78
1.03
0.07
1.1
1.6
—
—
—
0
0
8
78
1.03
0.07
1.1
1.6
—
—
—
0
0
7
85
0.82
0.07
1.0
1.8
—
—
—
0
0
71
731
0.97
0.07
2.7
3.1
207.0
210.9
ng/l
0.03
63
674
8
92
0.87
0.06
1.1
1.8
—
—
—
0
0
18
193
0.93
0.06
1.6
1.2
1.7
9.7
u/ml
—
8
26
207
2093
0.99
0.05
4.6
4.7
21.5
21.4
%
0.04
105
1084
35
337
1.04
0.05
1.5
1.7
—
—
—
0
0
19
179
1.06
0.05
1.1
1.3
—
—
—
0
0
24
230
1.04
0.03
2.1
1.3
—
—
—
0
0
18
189
0.95
0.03
1.6
1.2
2.7
2.8
u/ml
—
6
19
12
126
0.95
0.00
1.4
1.6
—
—
—
0
0
48
482
1.00
0.00
3.4
3.6
1.6
1.9
mmol/l
0.36
30
371
10
95
1.05
0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
2.2
—
0
5
6
60
1.00
0.00
1.0
1.0
211.5
267.3
ng/l
—
6
34
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
6
60
1.00
0.00
1.0
1.0
25.3
39.2
ng/l
—
6
32
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
0.00
1.0
1.4
15.2
14.4
u/l
—
5
51
0
9
0.00
0.00
0.0
7.3
—
—
—
0
0
7
72
0.97
0.00
3.1
1.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_PANCREAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PANCREAS | 2.49 [2.03, 3.05] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.372 |
During the follow-up period (1.1.1998 — 31.12.2019), 488 out of 1662 females with CD2_BENIGN_PANCREAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PANCREAS | 3.362 [2.54, 4.46] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 427 out of 1130 males with CD2_BENIGN_PANCREAS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_PANCREAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.271% | 0.774% |
| 5 | 1.715% | 4.164% |
| 10 | 4.112% | 9.607% |
| 15 | 7.39% | 17.252% |
| 20 | 12.905% | 28.711% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_PANCREAS – Benign neoplasm: Pancreas
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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