Pregnant state, incidental

Z21_PREGNANT_STATE_INCIDENTAL

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule only females	293373
2. Check conditions None	293373
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Z33 Cause of death: ICD-10 — Z33 2 out of 7 registries used, show all original rules.	24
4. Check minimum number of events None	24
5. Include endpoints None	24
6. Filter based on genotype QC (FinnGen only)	24

Control definitions (FinnGen only)

Control exclude: Z21_PERSONS_ENCOUNTERI_HEALTH_SERVI_CIRCUMSTANC_RELATED_REPRODUCTION

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: Z3

NAME	Z21_PREGNANT_STATE_INCIDENTAL
CONTROL_EXCLUDE	Z21_PERSONS_ENCOUNTERI_HEALTH_SERVI_CIRCUMSTANC_RELATED_REPRODUCTION
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Z33
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Z33
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Pregnant state, incidental based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	24	24	-
Unadjusted period prevalence (%)	0.01	0.01	-
Median age at first event (years)	26.15	26.15	-

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3026008) Bacteria identified in Urine by Culture

7.77

5.25

3.0

1.9

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

5.75

4.27

4.2

3.3

—

(3015736) pH of Urine

5.43

3.89

3.5

2.5

—

(3023511) Choriogonadotropin [Units/volume] in Urine

6.89

3.68

1.6

1.4

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

4.94

3.57

1.9

2.0

—

(36304419) Bacteria [Presence] in Urine

4.64

3.18

4.6

2.4

—

(3022621) pH of Urine by Test strip

12.11

3.12

7.8

1.8

—

(3021589) Normoblasts [#/volume] in Blood

4.63

3.03

5.3

6.0

0.0

e9/l

0.00

(3026782) Osmolality of Urine

5.11

2.95

4.3

2.6

477.4

540.6

mosm/kgh2o

—

(3042936) Bacteria identified in Isolate by Culture

5.70

2.71

1.3

3.0

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

6.25

2.57

1.7

1.0

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

3.77

2.50

6.4

2.4

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

4.02

2.39

3.3

2.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

3.47

2.23

1.9

1.5

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

3.47

2.16

1.5

1.8

—

(3044640) Blood type and Crossmatch panel - Blood

3.49

2.08

2.1

2.2

—

(40768804) Tissue Pathology biopsy report

3.20

1.96

1.6

2.1

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

3.18

1.95

5.8

8.8

1.2

mmol/l

0.13

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

3.14

1.90

1.8

1.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

3.52

1.81

2.0

2.2

—

(3044889) 12 lead EKG panel

3.09

1.81

1.9

2.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

2.91

1.65

6.4

2.2

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

2.87

1.64

4.4

5.3

1.2

mmol/l

0.42

(3023368) Bacteria identified in Blood by Culture

3.10

1.60

3.1

2.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

2.75

1.52

2.1

1.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

120

2.99

1.52

7.0

3.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

3.66

1.52

1.8

1.4

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

3.22

1.36

2.0

1.8

28.4

30.2

—

(3019832) Treponema pallidum Ab [Presence] in Serum

2.52

1.22

1.6

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

2.43

1.21

2.7

2.0

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

2.73

1.15

4.0

1.6

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.59

1.09

1.6

1.3

—

(40761511) CBC panel - Blood by Automated count

210

+∞

1.06

13.7

7.4

—

(40758558) Short blood count panel - Blood

2.28

1.01

3.1

9.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

2.20

0.99

2.1

1.7

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

2.11

0.90

2.2

1.9

3.0

2.7

mg/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.86

0.66

2.0

1.8

—

(42870588) Differential panel, method unspecified - Blood

1.76

0.64

4.6

4.5

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.00

0.62

0.0

4.3

—

25.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

1.84

0.62

6.4

3.0

—

(1761868) Lipid panel - Serum or Plasma

0.53

0.59

2.4

1.8

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.78

0.56

1.7

1.6

—

(3019225) pH of Specimen

0.00

0.43

0.0

9.1

—

(4010399)

0.00

0.43

0.0

1.3

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.43

0.0

1.5

—

(3003694) ABO and Rh group [Type] in Blood

1.49

0.36

1.9

1.3

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.46

0.33

3.5

4.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.28

0.24

1.2

1.5

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.22

0.0

1.5

—

(3010813) Leukocytes [#/volume] in Blood

228

+∞

0.22

21.0

13.2

7.7

6.9

e9/l

1.37

222

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

0.00

0.22

0.0

1.4

—

(3007461) Platelets [#/volume] in Blood

226

+∞

0.20

21.1

13.3

288.4

280.9

e9/l

0.23

221

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

187

0.85

0.10

3.8

3.1

4.9

4.7

mmol/l

0.45

175

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

186

0.87

0.10

3.8

3.0

1.4

1.5

mmol/l

0.31

174

(3015377) Calcium [Moles/volume] in Serum or Plasma

0.79

0.09

2.6

3.8

2.3

mmol/l

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

182

1.21

0.09

5.9

3.6

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

13.5

—

0.6

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

1.3

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

13.1

—

837.1

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

187

1.08

0.00

3.7

3.1

3.0

2.8

mmol/l

0.55

176

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

1.2

—

(3022313) Gas panel - Capillary blood

0.00

0.0

7.4

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.0

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

0.00

0.0

6.8

—

23.2

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.0

1.4

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

116.2

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

177

1.07

0.00

3.4

2.8

1.5

1.1

mmol/l

1.09

165

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.2

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

5.6

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.4

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.4

—

12.6

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

14.1

—

1403.9

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: Z21_PREGNANT_STATE_INCIDENTAL – Pregnant state, incidental

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Pregnant state, incidental

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Pregnant state, incidental (Z21_PREGNANT_STATE_INCIDENTAL)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Relationships between endpoints