Dermatitis due to ingested food

L12_FOODDERMAT

skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L27.2
  • Hospital discharge: ICD-8 6925
  • Cause of death: ICD-10 L27.2
  • Cause of death: ICD-8 6925

2 out of 7 registries used, show all original rules.

1578

4. Check minimum number of events

None

1578

5. Include endpoints

None

1578

6. Filter based on genotype QC (FinnGen only)

1578

Control definitions (FinnGen only)

Control exclude
L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L27
Name in latin
Dermatitis ex cibo devorato

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 54667 23247 31410
Only index persons 37769 16243 21526
Unadjusted period prevalence (%)
Whole population 0.79 0.67 0.88
Only index persons 0.73 0.60 0.82
Median age at first event (years)
Whole population 1.20 1.28 1.14
Only index persons 1.19 1.31 1.10

-FinnGen-

Key figures

All Female Male
Number of individuals 1578 1000 578
Unadjusted period prevalence (%) 0.31 0.34 0.25
Median age at first event (years) 3.35 4.20 1.89

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1367
Matched controls
13257
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L27.2
ICD-10 Finland
Dermatitis due to ingested food
4503599627370496.0
323.0
1340
11
501
Kela drug reimbursment
Cow's milk and / or soy protein allergy in young children
42.7
323.0
422
137
L20.0
ICD-10 Finland
Besnier prurigo
+∞
323.0
786
*
C01CA24
ATC
epinephrine; parenteral
19.8
323.0
534
416
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
15.8
261.3
462
414
D07AA02
ATC
hydrocortisone; topical
9.1
249.3
637
1162
E0000UV
ATC
NA
6.9
234.6
940
3207
XQ800
NOMESCO Finland
Prick test
11.6
222.1
458
550
J45.0
ICD-10 Finland
Predominantly allergic asthma
10.4
221.7
492
679
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
8.3
192.5
494
843
D07BA04
ATC
hydrocortisone and antiseptics; topical
8.1
191.2
504
895
E000002
ATC
NA
7.8
188.7
514
956
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
26.8
186.4
265
118
E000001
ATC
NA
6.3
185.4
630
1582
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
+∞
178.2
169
*
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
+∞
177.2
168
*
L20
ICD-10 Finland
Atopic dermatitis
+∞
163.1
155
*
R06AE07
ATC
cetirizine; oral
4.5
145.0
870
3741
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
5.6
133.8
466
1117
D07AB08
ATC
desonide; topical
8.6
119.1
282
390
R03AC02
ATC
salbutamol; inhalant
3.7
111.4
928
4809
S01GX01
ATC
cromoglicic acid; ophthalmic
4.3
108.1
506
1594
R03BA05
ATC
fluticasone; inhalant
4.2
102.7
498
1606
T78.4
ICD-10 Finland
Allergy, unspecified
8.1
99.0
241
342
D11AH01
ATC
tacrolimus; topical
206.8
95.6
99
5
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
5.9
94.6
298
602
R06AX27
ATC
desloratadine; oral
3.4
93.6
662
2866
E000003
ATC
NA
11.6
93.6
183
175
N05BB01
ATC
hydroxyzine; systemic
9.2
92.8
207
253
D07AB02
ATC
hydrocortisone butyrate; topical
4.2
88.4
410
1240
R06AE09
ATC
levocetirizine; oral
4.2
86.1
386
1127
E000006
ATC
NA
8.1
82.9
200
276
R03BA02
ATC
budesonide; inhalant
4.1
82.7
379
1124
XQ802
NOMESCO Finland
Epicutan test
56.7
82.2
98
18
J45.9
ICD-10 Finland
Asthma, unspecified
4.0
76.2
358
1075
R03DC03
ATC
montelukast; oral
4.0
75.8
364
1114
H02AB06
ATC
prednisolone; systemic
3.2
75.0
545
2304
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
+∞
73.8
71
*
D07AC13
ATC
mometasone; topical
4.0
70.6
331
984
R06AX13
ATC
loratadine; oral
3.9
68.2
329
1000
D02AX
ATC
Other emollients and protectives
6.7
67.4
183
297
XQ830
NOMESCO Finland
Exposure to foodstuff
66.7
67.2
78
12
D11AX14
ATC
[U] tacrolimus; topical
+∞
64.4
62
*
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
30.4
59.1
80
27
R03AC03
ATC
terbutaline; inhalant
4.1
56.7
250
691
D07AC01
ATC
betamethasone; topical
3.3
55.1
328
1157
E000007
ATC
NA
5.5
54.6
174
343
505
Kela drug reimbursment
Allergy to cow's milk in infants
21.6
53.7
80
38
Z51.6
ICD-10 Finland
Desensitization to allergens
9.7
53.1
112
121
D11AH02
ATC
pimecrolimus; topical
+∞
52.9
51
*
J30.3
ICD-10 Finland
Other allergic rhinitis
6.5
52.2
144
236
D07CA01
ATC
hydrocortisone and antibiotics; topical
3.5
51.3
272
873
L20.8
ICD-10 Finland
Other atopic dermatitis
+∞
50.8
49
*
D11AX15
ATC
[U] pimecrolimus; topical
+∞
48.7
47
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.9
48.2
217
605
D09AB01
ATC
zinc bandage without supplements; topical
41.8
46.3
58
14
R01AD09
ATC
mometasone; nasal
2.3
45.9
615
3440
D02AE01
ATC
carbamide; topical
6.2
45.7
130
221
T78.0
ICD-10 Finland
Anaphylactic shock due to adverse food reaction
71.7
43.7
50
7
A92
ICPC
Allergy/allergic reaction NOS
4.4
42.7
169
416
J45
ICD-10 Finland
Asthma
4.0
42.3
187
510
J45.8
ICD-10 Finland
Mixed asthma
8.3
40.5
93
116
J45.1
ICD-10 Finland
Nonallergic asthma
3.6
40.0
196
583
R01AD08
ATC
fluticasone; nasal
2.6
39.3
344
1515
XG410
NOMESCO Finland
Flow-volume spirometry
5.4
36.2
114
219
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
+∞
34.1
33
*
L50.0
ICD-10 Finland
Allergic urticaria
6.3
34.1
94
153
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.7
32.2
151
430
S87
ICPC
Dermatitis/atopic eczema
5.8
31.9
94
167
D07CC01
ATC
betamethasone and antibiotics; topical
3.4
31.7
166
516
R06AX22
ATC
ebastine; oral
3.1
31.7
192
663
XG474
NOMESCO Finland
Exhalation nntrogen oxide
5.0
30.8
104
216
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.1
30.7
186
641
R01AD12
ATC
fluticasone furoate; nasal
2.1
30.4
470
2665
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
29.2
30.4
41
14
R96
ICPC
Asthma
3.5
30.3
150
446
E000004
ATC
NA
8.0
29.7
69
88
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
18.2
27.1
42
23
69250
ICD-8 Finland
Other eczema and dermatitis, Due to food
+∞
26.9
26
*
D07BC01
ATC
betamethasone and antiseptics; topical
4.8
26.6
92
196
WQ000
NOMESCO Finland
Hyposensibilisation
8.8
26.3
57
65
R01AC01
ATC
cromoglicic acid; nasal
4.5
26.1
96
218
R03AK07
ATC
formoterol and budesonide; inhalant
2.5
24.8
210
885
6931A
ICD-9 Finland
Dermatitis due to substances taken internally, Due to food
+∞
23.7
23
*
D07AC14
ATC
methylprednisolone aceponate; topical
5.8
23.3
67
116
R06.2
ICD-10 Finland
Wheezing
3.4
22.7
118
363
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
2.1
22.1
311
1659
D07AB01
ATC
clobetasone; topical
7.2
21.6
53
74
J46
ICD-10 Finland
Status asthmaticus
7.3
20.6
50
69
S01GX02
ATC
levocabastine; ophthalmic
3.6
20.6
98
282
H02AB07
ATC
prednisone; oral
3.1
19.2
108
352
D07AD01
ATC
clobetasol; topical
3.2
18.9
102
323
TQW80
NOMESCO Finland
Local dermatologic skincare
8.5
18.8
41
48
J01DA01
ATC
[U] cefalexin; systemic
1.7
18.4
580
4026
R06AX26
ATC
fexofenadine; oral
3.5
17.8
85
246
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.0
17.6
108
374
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.3
17.6
169
757
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
+∞
17.5
17
*
J30.19
ICD-10 Finland
Pollen allergy UNS
3.2
17.5
94
297
H02AB04
ATC
methylprednisolone; systemic
2.8
17.2
113
409
R01AD05
ATC
budesonide; nasal
3.6
16.6
77
218
L23.5
ICD-10 Finland
Allergic contact dermatitis due to other chemical products
62.2
16.5
19
*
D11AH05
ATC
dupilumab; topical
+∞
16.5
16
*
395
Kela drug reimbursment
Dupilumab
+∞
16.5
16
*
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
4.2
16.0
61
145
R03BC01
ATC
cromoglicic acid; inhalant
7.7
16.0
37
48
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
2.7
15.9
116
448
S01AD03
ATC
aciclovir; ophthalmic
6.5
15.5
40
61
L50.9
ICD-10 Finland
Urticaria, unspecified
3.0
15.4
89
296
S01GX09
ATC
olopatadine; ophthalmic
4.1
15.2
59
143
506
Kela drug reimbursment
Allergy to cow's milk and hypersensibility to conventional formula in infants
23.0
14.9
21
9
J30.4
ICD-10 Finland
Allergic rhinitis, unspecified
3.2
14.6
78
247
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
35.3
14.2
18
5
R03BA01
ATC
beclometasone; inhalant
2.6
13.8
104
408
S01GX08
ATC
ketotifen; ophthalmic
3.2
13.7
73
230
L30.3
ICD-10 Finland
Infective dermatitis
7.2
13.4
32
44
R06.0
ICD-10 Finland
Dyspnoea
1.9
13.2
200
1082
R05
ICD-10 Finland
Cough
1.8
12.9
253
1491
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
12.9
203
1114
R02
ICPC
Shortness of breath/dyspnoea
2.1
12.5
142
683
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
2.2
12.5
128
587
J01FA01
ATC
erythromycin; systemic
2.0
12.5
166
854
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
15.1
12.4
20
13
J01DB01
ATC
cefalexin; oral
1.5
12.1
964
8051
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
5.6
11.9
34
60
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
7.3
11.9
28
38
D07XB05
ATC
dexamethasone, combinations; topical
6.3
11.9
31
49
L50.3
ICD-10 Finland
Dermatographic urticaria
5.7
11.8
33
57
R03AC12
ATC
salmeterol; inhalant
5.2
11.8
36
69
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
11.7
233
1379
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
6.7
11.6
29
43
L23.6
ICD-10 Finland
Allergic contact dermatitis due to food in contact with skin
63.5
11.5
13
*
J01FA10
ATC
azithromycin; systemic
1.5
11.4
945
7901
R06AX12
ATC
terfenadine; oral
4.4
11.1
39
87
R03BA08
ATC
ciclesonide; inhalant
2.6
11.0
81
316
R06AX11
ATC
astemizole; oral
3.7
10.9
47
127
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
3.1
10.9
59
190
L50.8
ICD-10 Finland
Other urticaria
4.7
10.9
36
76
X57
ICD-10 Finland
Unspecified privation
4.5
10.8
37
81
J01FF01
ATC
clindamycin; systemic
1.8
10.8
194
1110
R01AD11
ATC
triamcinolone; nasal
2.7
10.8
75
283
J01FA09
ATC
clarithromycin; systemic
1.6
10.7
380
2629
W84
ICD-10 Finland
Unspecified threat to breathing
11.7
10.6
19
16
R06AX18
ATC
acrivastine; oral
8.1
10.6
23
28
R03CC02
ATC
salbutamol; systemic
1.6
10.5
351
2391
T78.1
ICD-10 Finland
Other adverse food reactions, not elsewhere classified
21.0
10.5
15
7
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
10.3
207
1227
134
Kela drug reimbursment
General erythroderma
107.5
10.3
11
*
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
107.5
10.3
11
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
10.2
145
760
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.9
10.2
162
887
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.2
9.9
51
159
B00.10
ICD-10 Finland
Herpes simplex facialis
8.9
9.8
20
22
R03DA04
ATC
theophylline; systemic, rectal
4.3
9.7
35
81
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.7
9.6
222
1370
A03FA02
ATC
cisapride; oral, rectal
2.6
9.6
68
260
XQ820
NOMESCO Finland
Exposure to medicinal substance
13.1
9.5
16
12
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
9.4
810
6678
R03AC13
ATC
formoterol; inhalant
4.5
9.4
32
70
UJF32
NOMESCO Finland
Coloscopy
1.9
9.4
131
684
WZC30
NOMESCO Finland
Teaching
2.1
9.3
108
525
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.4
9.3
43
124
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.6
9.2
310
2107
R06AE08
ATC
NA
11.2
8.9
16
14
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.6
8.8
61
231
XQ899
NOMESCO Finland
Other assessment of skin
18.2
8.8
13
7
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
4.3
8.8
31
71
D07CB01
ATC
triamcinolone and antibiotics; topical
6.4
8.7
22
34
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
8.7
268
1780
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.4
8.7
73
308
J05AB01
ATC
aciclovir; systemic
1.8
8.6
165
963
L27.1
ICD-10 Finland
Localized skin eruption due to drugs and medicaments
48.8
8.6
10
*
A07EB01
ATC
cromoglicic acid; oral
48.8
8.6
10
*
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
2.8
8.5
54
194
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
4.6
8.5
28
60
H03.1*B00.5
ICD-10 Finland
Herpesviral dermatitis of eyelid
26.9
8.4
11
*
W79
ICD-10 Finland
Inhalation and ingestion of food causing obstruction of respiratory tract
26.9
8.4
11
*
T78.3
ICD-10 Finland
Angioneurotic oedema
6.8
8.3
20
29
R01AD01
ATC
beclometasone; nasal
2.1
8.3
95
461
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
8.3
169
1004
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
8.3
231
1494
D07XC01
ATC
betamethasone, combinations; topical
2.5
8.3
63
251
L26
ICD-10 Finland
Exfoliative dermatitis
+∞
8.2
8
*
S01GX04
ATC
nedocromil; ophthalmic
5.2
8.2
24
45
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
8.0
769
6378
49300
ICD-8 Finland
Asthma, bronchiale
11.4
7.9
14
12
A02BC01
ATC
omeprazole; systemic
1.7
7.9
176
1073
R01AC02
ATC
levocabastine; nasal
3.6
7.8
33
90
R03BB04
ATC
tiotropium bromide; inhalant
3.2
7.7
38
117
SPAT1312
SPAT
General health counselling
1.4
7.6
606
4846
R03BC03
ATC
nedocromil; inhalant
3.1
7.5
39
124
SPAT1059
SPAT
Spirometry at the office
3.1
7.5
39
125
R03AK08
ATC
formoterol and beclometasone; inhalant
3.3
7.2
34
101
SPAT1058
SPAT
PEF monitoring instruction
2.0
7.2
84
411
XQ801
NOMESCO Finland
Intracutantest
19.5
7.0
10
5
A02BA02
ATC
ranitidine; systemic
2.2
6.9
69
318
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
16.3
6.6
10
6
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
7.0
6.5
15
21
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.9
6.5
38
131
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
4.8
6.5
20
41
XQ848
NOMESCO Finland
Dermatological photography
4.8
6.5
20
41
R04
ICPC
Breathing problem other
2.8
6.4
39
139
J04.0
ICD-10 Finland
Acute laryngitis
1.8
6.4
109
613
EMB30
NOMESCO Finland
Adenotomy
1.5
6.3
210
1413
E0001A1
ATC
NA
2.5
6.3
48
194
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
6.3
59
264
L27.9
ICD-10 Finland
Dermatitis due to unspecified substance taken internally
+∞
6.2
6
*
H13.1*B00.5
ICD-10 Finland
Herpesviral conjunctivitis
+∞
6.2
6
*
L27.8
ICD-10 Finland
Dermatitis due to other substances taken internally
+∞
6.2
6
*
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
10.7
6.2
11
10
Z27.4
ICD-10 Finland
Need for immunization against measles-mumps-rubella [MMR]
17.6
6.2
9
5
7080A
ICD-9 Finland
Urticaria, Allergic urticaria
17.6
6.2
9
5
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
6.1
468
3685
J35.2
ICD-10 Finland
Hypertrophy of adenoids
1.6
6.1
145
899
J01FA06
ATC
roxithromycin; oral
1.5
6.1
214
1459
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
6.0
292
2122
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.1
6.0
62
290

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
199
56
39.04
310.73
1.4
1.1
21.7
4.7
u/ml
1.85
172
36
155
28
59.04
266.99
1.2
1.1
6.3
4.0
u/ml
0.25
139
23
169
49
37.10
261.04
2.0
1.1
15.6
0.1
u/ml
—
62
7
175
96
19.63
213.81
1.3
1.1
38.4
4.7
u/ml
1.47
151
67
107
15
73.65
191.56
2.1
1.1
15.2
0.1
u/ml
—
98
5
175
168
11.16
154.97
1.8
1.0
20.8
0.8
u/ml
2.33
149
64
178
178
10.73
153.20
1.8
1.1
10.0
0.8
u/ml
4.28
145
86
94
31
31.00
138.74
1.1
1.0
9.7
0.5
u/ml
—
62
10
93
32
29.69
135.39
1.1
1.0
2.2
0.0
u/ml
1.56
62
12
80
19
42.67
129.04
1.1
1.0
3.0
4.0
u/ml
0.10
64
13
80
23
35.24
122.79
1.1
1.0
0.5
0.0
u/ml
2.64
60
16
73
20
36.82
113.44
1.1
1.1
1.9
0.6
u/ml
1.45
62
14
264
572
5.14
111.10
1.2
1.1
5.2
2.1
u/ml
2.13
105
174
262
580
5.02
107.35
1.3
1.1
7.0
7.9
u/ml
0.29
219
357
76
29
26.47
106.61
1.1
1.0
0.6
1.6
u/ml
—
56
10
347
972
4.13
105.21
1.8
1.3
1344.4
189.4
u/ml
6.27
337
899
131
146
9.34
103.48
1.3
1.0
1.3
0.4
u/ml
1.46
52
27
272
650
4.66
101.30
1.3
1.1
2.9
3.5
u/ml
0.25
210
335
251
564
4.91
100.76
1.3
1.1
2.1
1.0
u/ml
1.35
203
316
76
52
14.74
82.17
1.6
1.2
8.3
5.2
ug/l
0.48
70
43
61
27
22.60
80.77
1.1
1.0
15.7
2.9
u/ml
—
50
9
85
75
11.48
78.93
1.2
1.3
1.4
0.6
u/ml
0.50
22
20
174
428
4.28
61.30
1.1
1.1
11.9
3.0
u/ml
4.81
118
201
153
395
4.02
50.27
1.1
1.1
12.8
8.2
u/ml
1.17
111
198
131
345
3.90
41.73
1.1
1.0
1.3
0.2
u/ml
1.86
75
88
886
6150
1.89
32.47
7.1
8.0
0.3
0.2
e9/l
22.46
791
5346
858
5967
1.85
30.48
7.0
7.3
0.0
0.0
e9/l
0.64
756
5077
856
5954
1.84
30.34
7.0
7.4
0.6
0.5
e9/l
1.58
756
5071
827
5725
1.83
29.42
6.9
7.5
4.3
2.8
%
25.17
781
5401
883
6244
1.83
29.20
7.0
7.2
2.3
2.2
e9/l
1.36
801
5463
829
5773
1.81
28.62
7.0
7.6
8.0
8.1
%
0.63
788
5463
134
455
3.01
28.50
1.5
1.3
—
—
—
0
0
800
5536
1.80
27.98
6.9
7.6
0.6
0.6
%
0.03
759
5230
646
4199
1.82
27.82
6.3
8.0
—
—
—
0
0
858
6094
1.78
27.15
6.9
7.2
33.5
33.5
%
0.00
821
5768
844
5974
1.78
26.94
6.7
7.1
50.8
52.2
%
2.42
808
5675
918
6717
1.76
25.54
7.8
9.3
3.7
3.7
e9/l
0.26
809
5711
43
77
5.50
21.93
1.0
1.0
17.5
4.3
u/ml
—
8
6
180
865
2.13
18.20
1.5
1.3
—
—
—
0
0
750
5713
1.51
13.88
8.5
9.0
0.0
0.0
e9/l
0.78
606
4524
922
7372
1.49
13.16
4.1
3.6
8.0
7.4
mm/h
0.86
862
6832
18
24
7.30
12.13
1.2
1.0
—
—
—
0
0
446
3124
1.52
11.88
5.9
8.1
—
—
—
0
0
325
2157
1.57
10.93
3.3
2.9
145.4
104.1
ug/g
0.77
258
1685
14
5
27.18
10.53
1.0
1.0
0.6
—
u/ml
—
5
0
200
1203
1.69
9.96
1.9
1.6
—
—
—
0
0
369
2568
1.50
9.87
5.3
4.3
—
—
—
0
0
514
3843
1.43
9.41
1.7
1.5
1.7
1.7
g/l
0.01
302
2165
549
4256
1.37
7.80
1.6
1.6
1.0
2.4
u/ml
3.58
118
921
138
816
1.69
7.31
1.5
1.2
—
—
—
0
0
119
701
1.69
6.41
4.5
4.0
0.3
0.5
%
0.50
25
144
36
136
2.59
6.41
1.2
1.2
—
—
—
0
0
1317
11854
1.43
6.31
11.2
9.2
20.0
21.4
mg/l
0.81
970
8356
1039
9015
1.32
6.29
3.9
3.5
14.3
14.4
pmol/l
0.43
929
8094
165
1059
1.56
6.29
3.0
3.2
10.2
9.7
g/l
0.99
154
1006
207
1406
1.48
6.05
1.3
1.2
13.7
27.4
iu/ml
2.17
59
326
182
1206
1.51
6.00
1.6
1.5
437.2
12687000.9
pmol/l
0.80
155
1072
123
748
1.63
5.88
4.6
4.5
0.6
0.7
%
0.11
31
202
38
154
2.41
5.87
1.0
1.1
—
—
—
0
0
173
1147
1.51
5.69
1.3
1.3
30.8
372.0
titre
—
6
42
207
1425
1.46
5.65
1.6
1.5
466.4
512.9
titre
0.14
50
230
115
695
1.64
5.64
4.8
4.6
0.0
0.0
%
0.20
26
161
117
711
1.63
5.62
4.7
4.6
0.1
0.1
%
0.05
29
185
1228
10983
1.35
5.61
12.7
12.5
13.1
13.2
%
0.11
1202
10749
46
208
2.16
5.54
1.2
1.1
4.6
6.7
iu/ml
—
9
34
178
1199
1.48
5.42
2.4
2.3
321.1
367.8
nmol/l
3.05
167
1129
67
351
1.88
5.40
1.2
1.1
—
—
—
0
0
49
230
2.09
5.38
3.7
3.6
51.3
52.7
%
0.26
49
230
67
352
1.87
5.36
1.2
1.1
—
—
—
0
0
48
225
2.09
5.29
3.2
3.3
3.6
3.6
e9/l
0.05
48
225
142
927
1.52
5.03
1.5
1.5
—
—
—
0
0
546
4442
1.28
5.00
9.0
9.2
1.2
1.2
mmol/l
0.57
483
3936
8
6
12.90
4.97
1.0
1.0
—
—
—
0
0
509
4111
1.28
4.93
11.0
9.8
1.2
1.2
mmol/l
0.88
477
3861
46
219
2.05
4.89
1.2
1.1
—
—
—
0
0
47
226
2.03
4.87
1.4
1.3
370.5
359.3
ug/g
0.12
22
104
400
3149
1.30
4.68
1.6
1.6
—
—
—
0
0
350
2707
1.32
4.66
3.6
3.1
0.0
0.0
estimate
0.41
140
1010
34
151
2.19
4.34
1.3
1.5
0.3
0.4
g/l
1.20
28
124
189
1344
1.40
4.32
1.3
1.2
8.1
7.9
u/ml
0.01
75
476
11
25
4.26
4.32
1.7
2.1
—
—
—
0
0
59
321
1.80
4.28
1.1
1.2
—
—
—
0
0
34
152
2.18
4.28
1.3
1.5
—
—
—
0
0
73
424
1.69
4.23
1.1
1.1
18.8
13.9
au/ml
—
5
21
42
206
1.99
4.17
1.3
1.2
—
—
—
0
0
262
1977
1.33
4.12
2.6
2.2
43.9
34.6
ng/l
0.10
91
728
128
854
1.48
4.12
1.7
1.5
1145.8
1126.1
nmol/l
0.09
91
667
143
976
1.45
4.10
3.7
3.0
—
—
—
0
0
339
2656
1.29
4.06
3.1
2.7
2.4
2.6
mg/l
1.32
294
2345
332
2605
1.29
3.92
1.8
1.5
93.1
97.4
pmol/l
1.02
189
1409
771
6661
1.23
3.85
6.7
5.6
92.4
93.3
u/l
0.14
724
6233
123
826
1.47
3.85
2.1
1.9
1.2
1.1
g/l
0.15
116
783
241
1816
1.33
3.83
4.6
4.0
—
—
—
0
0
14
42
3.23
3.80
1.0
1.1
—
—
—
0
0
1136
10230
1.25
3.79
4.5
4.0
2.0
2.0
mu/l
0.02
1067
9645
17
58
2.84
3.74
1.1
1.1
23.7
17.8
u/ml
—
7
14
1471
13736
1.49
3.68
15.6
13.6
271.5
265.6
e9/l
2.92
1422
13217
244
1852
1.32
3.68
2.3
2.4
201.2
274.4
u/l
0.65
236
1776
1474
13770
1.50
3.68
15.7
13.7
135.4
135.1
g/l
0.42
1455
13542
99
650
1.50
3.48
2.6
1.9
4.3
4.2
e9/l
0.12
87
556
1471
13755
1.47
3.44
15.4
13.4
87.9
87.6
fl
1.62
1451
13529
1471
13757
1.46
3.41
15.4
13.4
29.5
29.4
pg
1.84
1452
13532
13
40
3.15
3.40
1.1
1.2
—
—
—
0
0
1471
13761
1.46
3.36
15.5
13.5
4.6
4.6
e12/l
0.73
1417
13206
395
3222
1.24
3.32
6.9
6.3
38.1
37.9
g/l
0.34
375
3033
11
31
3.43
3.28
5.0
2.6
—
—
—
0
0
41
219
1.82
3.23
1.6
1.7
1.4
0.8
g/l
1.01
36
184
48
269
1.74
3.23
1.0
1.0
8.7
8.8
mu/l
0.03
43
229
31
151
2.00
3.20
1.3
1.8
—
—
—
0
0
1471
13775
1.44
3.19
15.5
13.5
6.9
6.8
e9/l
1.05
1417
13228
109
746
1.44
3.13
1.4
1.4
—
—
—
0
0
39
208
1.83
3.10
1.0
1.0
3.4
3.2
kpa
0.37
32
172
828
7297
1.20
3.10
4.2
3.8
—
—
—
0
0
183
1373
1.32
3.01
6.5
9.2
0.8
0.8
mmol/l
0.31
172
1324
17
66
2.50
2.98
1.3
1.2
—
—
—
0
0
14
49
2.77
2.98
1.7
1.3
—
—
—
0
0
607
5219
1.20
2.94
4.6
4.3
0.0
0.0
estimate
0.50
144
1045
39
212
1.79
2.93
1.0
1.0
—
—
—
0
0
39
212
1.79
2.93
1.0
1.0
-2.5
-1.2
mmol/l
—
6
45
39
212
1.79
2.93
1.0
1.0
7.3
7.2
kpa
0.22
32
175
302
2425
1.25
2.90
5.8
3.9
1.1
1.1
inr
0.55
132
818
155
1142
1.34
2.89
1.3
1.3
145.2
130.8
iu/ml
0.14
50
372
611
5264
1.19
2.88
3.4
3.1
0.0
0.0
estimate
0.00
138
1024
24
112
2.08
2.80
1.0
1.0
—
—
—
0
0
36
194
1.81
2.79
3.3
4.5
1.7
2.0
mmol/l
0.31
20
99
178
1345
1.31
2.79
1.5
1.5
—
—
—
0
0
604
5213
1.19
2.76
3.4
3.0
0.0
0.0
estimate
0.00
135
992
1154
10538
1.21
2.72
11.5
9.7
139.5
139.5
mmol/l
0.09
1114
10162
276
2210
1.25
2.72
3.4
3.6
7.4
7.4
ph
0.12
60
404
202
1559
1.28
2.70
2.6
2.3
—
—
—
0
0
65
414
1.53
2.70
4.3
4.1
26.4
25.0
nmol/l
0.26
65
405
11
36
2.96
2.63
8.4
6.1
—
—
—
0
0
386
3212
1.21
2.62
3.8
3.5
44.8
81.5
e6/l
0.49
293
2373
32
170
1.83
2.61
2.0
2.8
1029.3
761.4
e6/l
—
6
28
1154
10557
1.20
2.57
11.5
9.7
3.9
3.9
mmol/l
0.38
1112
10130
51
312
1.59
2.53
1.6
1.8
—
—
—
0
0
212
1661
1.26
2.52
1.2
1.2
—
—
—
0
0
791
7021
1.17
2.51
4.3
3.7
1916.4
795.4
e6/l
0.30
21
87
263
2121
1.23
2.43
3.2
2.8
8.9
8.6
e6/l
0.08
229
1857
474
4045
1.18
2.41
5.9
6.1
17.6
15.3
umol/l
0.66
442
3703
635
5551
1.17
2.41
6.6
5.7
6.1
6.0
mmol/l
0.41
579
5034
103
734
1.38
2.41
2.3
2.2
4.8
13.8
au/ml
—
5
49
111
801
1.36
2.40
1.9
2.1
10.7
9.7
nmol/l
0.42
94
691
142
1067
1.31
2.35
4.4
5.7
1.4
1.4
%
0.20
134
998
18
81
2.15
2.33
1.8
1.2
—
—
—
0
0
252
2033
1.23
2.32
3.1
2.7
580.3
592.6
mosm/kgh2o
0.31
223
1750
1318
12248
1.23
2.30
11.7
11.3
40.0
40.0
%
0.09
1139
10545
174
1349
1.27
2.27
2.5
3.5
4512.7
3396.9
umol/l
0.14
149
1250
21
103
1.98
2.20
4.6
5.5
8.1
9.1
mg/l
0.35
15
86
189
1488
1.25
2.18
1.6
1.4
19.8
19.0
nmol/l
0.36
163
1322
117
1449
0.76
2.17
1.6
2.0
—
—
—
0
0
37
218
1.65
2.17
3.4
2.5
21.9
28.2
mg/l
0.71
20
141
5
9
5.36
2.15
1.2
1.1
251.2
217.7
umol/24h
—
5
9
696
6173
1.15
2.11
3.2
3.0
54.7
59.4
ug/l
0.41
650
5831
39
235
1.61
2.10
2.4
3.2
1.5
1.4
e9/l
0.14
30
155
297
2466
1.20
2.04
2.7
2.4
61.8
54.4
u/l
0.72
272
2265
351
2962
1.18
2.01
3.8
3.3
0.2
0.3
e6/l
0.65
262
2159
206
1665
1.22
1.88
7.9
9.9
1.2
1.3
mmol/l
1.17
196
1578
355
3019
1.17
1.85
3.7
3.3
—
—
—
0
0
8
28
2.76
1.78
1.1
1.6
—
—
—
0
0
96
714
1.31
1.76
3.0
3.4
4.8
5.0
pmol/l
0.70
85
652
113
862
1.28
1.73
2.0
1.9
6.0
6.8
u/l
0.93
85
629
35
217
1.57
1.72
3.1
3.9
—
—
—
0
0
28
164
1.66
1.72
2.5
2.8
17.5
17.4
%
0.03
13
87
8
29
2.67
1.71
1.5
1.7
—
—
—
0
0
117
899
1.27
1.69
2.0
1.8
9.4
11.1
iu/l
0.42
90
670
97
728
1.30
1.68
2.9
4.1
61.9
65.6
e9/l
0.55
66
473
231
1910
1.19
1.68
1.6
1.7
1.2
1.3
mmol/l
0.23
199
1721
14
66
2.05
1.66
1.6
2.7
—
—
—
0
0
42
276
1.48
1.61
2.1
1.9
6.0
4.9
iu/l
0.15
16
99
339
2913
1.15
1.54
2.8
2.2
—
—
—
0
0
215
2392
0.84
1.52
2.7
2.6
—
—
—
0
0
6
20
2.90
1.51
1.0
1.0
—
—
—
0
0
171
1393
1.20
1.48
2.6
2.7
13.6
14.4
umol/l
0.72
163
1322
344
2969
1.15
1.47
2.9
2.6
—
—
—
0
0
405
4285
0.88
1.45
1.8
1.7
—
—
—
0
0
11
50
2.13
1.44
2.3
2.6
0.2
0.2
e9/l
0.25
11
50
450
3960
1.13
1.43
4.4
4.0
87.6
64.3
e6/l
0.28
309
2551
34
221
1.49
1.40
2.6
3.2
8.9
10.1
%
0.39
29
187
15
78
1.86
1.39
1.1
1.1
1847.1
1484.1
miu/ml
0.65
15
78
25
152
1.59
1.38
1.2
1.2
—
—
—
0
0
901
8267
1.12
1.37
2.9
2.5
5.4
5.4
mmol/l
0.04
829
7655
161
1819
0.84
1.37
1.5
1.9
—
—
—
0
0
471
4167
1.13
1.37
3.1
2.9
—
—
—
0
0
44
303
1.41
1.36
2.1
2.4
—
—
—
0
0
12
58
2.00
1.36
1.2
1.1
—
—
—
0
0
277
2993
0.87
1.35
2.7
2.6
—
—
—
0
0
172
1421
1.19
1.30
9.2
9.9
7.4
7.4
ph
—
9
66
110
1281
0.81
1.29
1.5
2.5
—
—
—
0
0
303
2617
1.14
1.28
2.8
2.7
2.4
2.4
mmol/l
0.18
274
2390
141
1145
1.20
1.28
3.6
3.8
121.9
249.0
mg/l
0.65
99
877
172
1423
1.18
1.28
9.2
9.9
5.1
5.0
kpa
0.03
167
1373
164
1836
0.84
1.27
1.5
1.9
—
—
—
0
0
437
4568
0.89
1.27
4.3
4.0
—
—
—
0
0
151
1702
0.84
1.27
1.5
1.9
—
—
—
0
0
143
1165
1.20
1.26
4.3
4.5
17.9
12.7
mg/mmol
0.28
93
877
166
1855
0.85
1.26
1.5
1.9
—
—
—
0
0
756
6893
1.11
1.26
3.6
3.2
36.0
36.1
mmol/mol
0.17
703
6517
166
1852
0.85
1.24
1.5
1.9
—
—
—
0
0
67
502
1.30
1.24
1.3
1.2
—
—
—
0
0
47
334
1.37
1.23
1.1
1.1
—
—
—
0
0
5
18
2.68
1.23
1.0
1.4
—
—
—
0
0
8
35
2.21
1.23
4.8
3.3
—
—
—
0
0
185
1546
1.17
1.23
2.7
2.3
5176.0
6980.6
u/l
0.44
68
510
70
530
1.28
1.20
3.2
3.8
1.2
1.2
mmol/l
0.23
64
460
121
976
1.21
1.19
2.2
2.2
2.4
2.4
mmol/l
0.16
101
842
130
1057
1.20
1.18
2.2
1.9
—
—
—
0
0
23
143
1.56
1.18
3.3
4.6
—
—
—
0
0
31
206
1.46
1.18
10.6
5.5
—
—
—
0
0
18
106
1.64
1.15
1.0
1.2
—
—
—
0
0
44
315
1.36
1.12
1.3
1.5
39.8
37.0
nmol/l
0.33
44
310
140
1154
1.18
1.11
2.8
2.8
21.3
23.0
%
0.72
129
1055
150
1244
1.18
1.11
1.5
1.5
—
—
—
0
0
11
56
1.90
1.11
1.6
1.4
0.8
1.2
nmol/l
0.92
11
49
22
139
1.53
1.07
1.0
1.4
—
—
—
0
0
45
328
1.33
1.04
1.2
1.2
—
—
—
0
0
11
58
1.83
1.01
1.1
1.4
—
—
—
0
0
10
51
1.89
1.01
1.6
1.8
55.6
52.1
%
—
5
42
291
2549
1.12
1.00
3.5
3.0
—
—
—
0
0
17
103
1.60
0.99
1.4
1.3
1.6
1.6
mmol/l
0.09
17
97
116
952
1.19
0.99
1.9
2.0
—
—
—
0
0
67
520
1.25
0.98
2.4
3.6
—
—
—
0
0
62
477
1.26
0.98
1.7
1.9
—
—
—
0
0
167
1414
1.15
0.97
12.8
10.6
—
—
—
0
0
120
990
1.18
0.97
1.7
1.6
372.8
333.0
mu/l
0.42
115
885
0
31
0.00
0.95
0.0
1.5
—
—
—
0
0
22
144
1.48
0.94
1.1
1.0
1.4
1.4
g/l
0.16
22
133
6
26
2.23
0.93
1.8
2.6
—
—
—
0
0
15
90
1.61
0.92
1.4
1.7
—
—
—
0
0
207
1787
1.13
0.91
3.3
3.1
4.0
3.8
e6/l
0.12
103
955
145
1223
1.16
0.90
9.5
9.8
—
—
—
0
0
38
278
1.32
0.88
1.5
1.6
—
—
—
0
0
9
150
0.58
0.88
1.2
1.8
—
—
—
0
0
1229
11577
1.10
0.87
12.7
12.0
334.9
334.4
g/l
1.12
1220
11457
17
107
1.54
0.87
3.2
1.4
—
—
—
0
0
14
84
1.61
0.86
1.1
1.1
—
—
—
0
0
21
287
0.70
0.85
3.2
3.6
3.8
4.9
ug/l
0.29
16
193
331
2949
1.10
0.85
1.7
1.7
—
—
—
0
0
1302
12307
1.11
0.84
9.5
7.7
—
—
—
0
0
8
44
1.75
0.83
1.1
1.7
5.6
7.2
u/l
—
8
36
143
1215
1.15
0.82
10.0
10.1
9.7
9.7
kpa
0.14
137
1179
366
3283
1.10
0.81
1.8
1.8
—
—
—
0
0
8
45
1.72
0.81
1.3
1.0
—
3.3
—
0
6
182
1573
1.13
0.81
7.6
9.1
—
7.4
—
0
8
24
167
1.39
0.78
3.2
7.4
—
—
—
0
0
20
135
1.43
0.76
2.7
3.8
1.3
1.0
%
0.28
14
108
29
210
1.34
0.75
2.4
3.6
17.2
17.7
%
0.05
29
205
146
1252
1.14
0.74
2.7
2.7
2.5
2.6
g/l
1.44
140
1179
79
647
1.19
0.73
1.3
1.2
—
—
—
0
0
59
470
1.22
0.73
1.7
1.9
110.0
96.5
u/ml
—
7
47
9
54
1.61
0.72
1.0
1.3
—
—
—
0
0
9
54
1.61
0.72
1.0
1.3
—
—
—
0
0
9
54
1.61
0.72
1.0
1.3
—
—
—
0
0
74
604
1.19
0.72
1.1
1.2
—
—
—
0
0
23
162
1.37
0.71
2.6
1.9
—
—
—
0
0
38
289
1.27
0.71
1.1
1.1
1.5
3.8
u/ml
0.86
15
103
30
221
1.31
0.70
1.4
1.5
—
—
—
0
0
179
1562
1.12
0.70
7.6
9.0
1.2
1.3
mmol/l
0.19
143
1233
226
1999
1.10
0.69
2.1
3.1
2.1
1.0
mg/l
0.72
148
1378
41
317
1.25
0.67
1.8
3.3
—
—
—
0
0
76
627
1.18
0.67
1.8
1.7
149.9
187.1
u/ml
0.74
32
334
11
67
1.59
0.66
1.8
2.6
556.7
1029.3
u/ml
1.61
11
67
47
371
1.23
0.65
2.7
3.1
67.2
65.9
g/l
0.50
47
354
19
132
1.39
0.64
1.2
1.3
—
29.5
—
0
8
7
43
1.57
0.64
4.0
8.0
—
—
—
0
0
32
242
1.28
0.63
1.3
1.2
329.5
195.6
iu/ml
—
10
75
11
68
1.56
0.63
2.5
1.5
31.4
32.5
pg
0.30
11
68
115
1242
0.88
0.62
2.8
3.5
657.5
959.3
ng/l
0.42
59
622
69
569
1.18
0.62
22.3
10.6
0.0
-0.0
mmol/l
0.02
57
434
0
19
0.00
0.60
0.0
1.7
—
—
—
0
0
53
428
1.20
0.60
1.3
1.7
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
30
227
1.28
0.60
20.3
4.2
—
—
—
0
0
14
93
1.45
0.60
1.3
1.1
—
—
—
0
0
14
93
1.45
0.60
1.4
1.6
—
—
—
0
0
25
185
1.31
0.59
1.6
1.3
—
—
—
0
0
30
228
1.27
0.58
1.0
1.1
—
—
—
0
0
100
854
1.14
0.58
2.3
2.3
31.9
29.4
u/l
0.39
85
704
11
70
1.52
0.57
2.3
2.2
43.5
39.5
%
—
5
20
66
548
1.17
0.56
4.3
3.0
—
—
—
0
0
42
335
1.21
0.55
1.5
1.6
0.2
0.3
nmol/l
0.85
34
266
6
36
1.61
0.55
3.0
2.4
12.5
12.1
%
—
6
36
6
36
1.61
0.55
2.8
2.4
—
—
—
0
0
20
145
1.33
0.54
1.5
1.5
9.3
11.0
mmol/l
—
5
19
8
121
0.63
0.54
1.9
5.0
—
—
—
0
0
33
257
1.24
0.54
1.1
1.1
—
—
—
0
0
10
63
1.53
0.54
2.6
2.4
—
188.3
—
0
10
46
372
1.20
0.53
20.9
13.8
0.7
0.7
%
0.86
46
372
525
4855
1.06
0.53
2.3
2.2
—
—
—
0
0
1215
11522
1.07
0.51
8.6
7.5
28.0
25.5
u/l
0.84
1182
11097
44
356
1.20
0.51
1.5
1.7
—
—
—
0
0
155
1371
1.10
0.50
7.2
8.9
23.7
23.7
mmol/l
0.11
146
1325
242
2184
1.08
0.50
1.7
1.6
—
—
—
0
0
26
199
1.26
0.50
3.1
2.6
—
—
—
0
0
7
103
0.65
0.49
1.7
1.7
—
—
—
0
0
7
105
0.64
0.48
1.0
1.1
—
—
—
0
0
283
2573
1.07
0.48
3.3
3.8
9.4
8.8
mmol/l
0.81
252
2360
82
702
1.13
0.48
7.0
7.1
58.1
56.2
ng/l
0.11
76
670
54
601
0.86
0.48
1.6
1.5
—
—
—
0
0
53
440
1.17
0.47
3.6
3.8
5.8
8.7
umol/l
1.11
45
361
53
589
0.86
0.47
1.6
1.5
—
—
—
0
0
120
1266
0.91
0.46
1.2
1.2
—
—
—
0
0
12
159
0.72
0.46
5.8
7.0
32.3
86.3
g/mol
1.89
12
144
7
47
1.44
0.46
1.0
1.2
—
0.2
—
0
11
73
623
1.13
0.45
1.9
1.5
—
—
—
0
0
73
623
1.13
0.45
2.0
2.3
—
—
—
0
0
20
150
1.29
0.45
5.6
3.6
79.3
83.7
mmol/l
0.12
15
134
53
587
0.87
0.45
1.6
1.5
—
—
—
0
0
7
48
1.41
0.45
1.3
1.2
—
—
—
0
0
7
48
1.41
0.45
2.6
2.1
—
—
—
0
0
16
116
1.33
0.45
1.2
1.2
—
—
—
0
0
552
5136
1.05
0.45
2.5
2.3
—
—
—
0
0
39
317
1.19
0.45
1.8
3.6
—
—
—
0
0
7
49
1.38
0.44
2.6
2.1
108.0
106.1
mmol/l
—
7
49
9
124
0.70
0.43
32.2
32.1
126.4
159.9
ug/l
—
9
114
5
30
1.61
0.43
1.4
1.4
—
—
—
0
0
10
67
1.44
0.42
1.0
1.2
—
—
—
0
0
5
31
1.56
0.42
1.0
2.3
—
—
—
0
0
71
610
1.13
0.41
1.1
1.1
—
—
—
0
0
11
76
1.40
0.40
1.1
1.1
211.5
232.2
iu/ml
0.10
11
76
38
312
1.18
0.40
7.0
5.8
24.3
24.4
mmol/l
0.06
38
299
7
100
0.67
0.39
1.0
1.2
—
—
—
0
0
35
286
1.18
0.39
5.6
10.2
23.8
23.3
mmol/l
0.41
35
263
11
143
0.74
0.39
1.7
4.7
—
—
—
0
0
5
34
1.42
0.39
2.0
1.8
—
1.8
—
0
5
11
77
1.38
0.38
1.5
4.3
123.7
265.0
umol/l
—
6
42
19
226
0.81
0.36
2.3
4.2
—
—
—
0
0
46
388
1.15
0.36
2.4
2.8
1.3
1.4
ug/l
0.05
39
348
11
78
1.36
0.36
2.0
1.2
—
—
—
0
0
44
483
0.87
0.35
5.1
6.4
0.2
0.5
g/l
2.01
29
330
18
140
1.24
0.33
1.1
1.2
—
—
—
0
0
98
871
1.09
0.33
1.2
1.2
—
—
—
0
0
7
50
1.35
0.31
2.6
2.1
3.7
3.9
mmol/l
—
7
50
38
322
1.14
0.30
36.2
13.6
—
—
—
0
0
20
160
1.21
0.29
1.7
1.6
12.7
12.9
%
0.48
20
160
8
105
0.73
0.29
1.0
1.2
—
—
nmol/l
—
0
0
16
125
1.24
0.29
3.1
2.2
—
—
—
0
0
16
125
1.24
0.29
2.1
2.4
—
—
—
0
0
7
55
1.23
0.29
1.0
1.2
—
—
—
0
0
12
145
0.80
0.27
1.8
1.8
—
—
—
0
0
9
115
0.75
0.27
9.8
10.9
0.6
0.6
mmol/l
—
9
109
275
2551
1.05
0.27
3.1
2.8
1.0
1.0
kg/l
1.02
55
394
8
63
1.22
0.27
1.0
1.1
—
—
—
0
0
62
546
1.10
0.27
1.6
1.6
—
—
—
0
0
100
900
1.07
0.26
1.3
1.4
—
—
—
0
0
5
36
1.34
0.23
1.0
1.2
—
—
—
0
0
5
38
1.27
0.22
1.2
1.3
139.0
134.8
nmol/l
—
5
38
103
1051
0.94
0.22
1.3
1.4
—
—
—
0
0
12
94
1.23
0.21
1.5
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
49.4
—
0
10
0
10
0.00
0.21
0.0
6.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.20
0.0
1.8
—
—
—
0
0
78
800
0.94
0.20
1.7
2.5
—
—
—
0
0
11
86
1.23
0.20
2.5
2.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
4.6
—
139.1
—
0
14
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
14
113
1.19
0.20
1.0
1.2
—
—
—
0
0
6
50
1.16
0.19
1.5
2.0
—
—
—
0
0
39
343
1.10
0.19
23.7
14.3
23.9
23.8
mmol/l
0.06
39
331
11
87
1.22
0.18
1.4
1.2
—
—
—
0
0
22
187
1.13
0.18
2.2
3.3
—
—
—
0
0
7
56
1.20
0.18
1.0
1.1
—
—
—
0
0
21
179
1.13
0.17
1.3
1.3
7.3
4.0
u/ml
—
10
88
5
66
0.73
0.17
5.0
3.3
—
—
—
0
0
24
257
0.90
0.16
1.5
1.9
—
—
—
0
0
6
76
0.76
0.15
1.2
1.0
—
—
—
0
0
6
76
0.76
0.15
1.3
1.1
—
—
—
0
0
6
77
0.75
0.15
1.0
1.1
—
—
—
0
0
7
86
0.78
0.14
2.6
2.2
—
—
—
0
0
7
86
0.78
0.14
1.0
1.2
—
—
nmol/l
—
0
0
39
349
1.08
0.14
1.7
3.1
34.1
10.1
e6/l
0.46
28
260
39
349
1.08
0.14
1.8
3.1
291.4
477.4
e6/l
0.21
29
272
90
830
1.05
0.14
1.4
1.3
252.1
237.2
miu/ml
0.15
56
405
18
193
0.90
0.13
1.6
2.1
—
—
—
0
0
13
109
1.15
0.13
2.8
1.9
—
—
—
0
0
78
784
0.96
0.12
1.2
1.2
—
—
—
0
0
856
8181
1.02
0.11
3.0
2.8
2.7
2.7
mmol/l
0.59
806
7691
12
101
1.15
0.11
1.0
1.1
260.8
287.5
mg/l
0.86
12
91
11
92
1.15
0.11
1.0
1.2
—
—
—
0
0
23
240
0.92
0.10
1.4
2.3
—
—
—
0
0
23
240
0.92
0.10
1.4
2.3
—
—
—
0
0
23
239
0.93
0.09
1.4
2.3
—
—
—
0
0
23
239
0.93
0.09
1.4
2.3
—
—
—
0
0
6
52
1.11
0.09
1.5
2.0
—
—
—
0
0
24
215
1.08
0.09
7.0
5.6
—
—
—
0
0
11
119
0.89
0.08
11.1
10.4
8.6
9.1
mg/l
0.14
11
112
6
56
1.03
0.08
1.0
1.1
—
—
—
0
0
801
7763
0.99
0.08
2.9
2.6
1.2
1.1
mmol/l
1.09
759
7345
846
8100
1.01
0.08
2.9
2.7
1.4
1.4
mmol/l
4.33
797
7648
7
63
1.07
0.08
1.3
2.3
—
—
—
0
0
7
64
1.05
0.08
2.7
2.3
17.2
16.3
umol/l
—
7
64
92
862
1.03
0.08
14.4
10.9
1.3
1.4
mmol/l
0.18
86
797
6
72
0.80
0.07
1.0
1.1
—
—
—
0
0
8
71
1.09
0.07
2.0
1.2
—
—
—
0
0
7
79
0.85
0.07
1.0
1.1
—
—
—
0
0
43
431
0.96
0.06
8.7
6.1
1.3
1.1
inr
—
8
89
366
3491
1.01
0.06
1.8
1.7
—
—
—
0
0
18
186
0.93
0.06
1.1
1.1
—
—
—
0
0
24
219
1.06
0.05
1.0
1.1
—
—
—
0
0
13
115
1.09
0.05
2.4
3.4
20.0
19.1
mmol/l
0.10
13
106
40
372
1.04
0.05
2.3
2.2
—
—
—
0
0
42
392
1.03
0.04
1.3
1.3
—
—
—
0
0
23
211
1.05
0.04
1.2
2.2
0.6
0.7
ug/l
—
9
90
16
145
1.06
0.03
1.0
1.0
—
—
—
0
0
13
134
0.93
0.03
1.2
1.3
1.7
1.1
promille
—
8
97
320
3062
1.01
0.03
2.0
1.9
—
—
—
0
0
43
403
1.03
0.03
4.9
5.7
105.7
176.3
ng/l
1.13
37
354
120
1141
1.01
0.03
5.3
5.7
8.9
6.0
umol/l
0.60
105
952
16
163
0.94
0.03
1.4
4.2
—
—
—
0
0
12
109
1.06
0.01
1.0
1.1
—
—
—
0
0
855
8241
1.00
0.00
3.0
2.8
4.4
4.5
mmol/l
1.28
810
7823
36
351
0.99
0.00
1.0
1.2
—
—
—
0
0
25
246
0.98
0.00
7.2
13.5
—
—
—
0
0
63
606
1.00
0.00
3.2
6.1
22.2
22.6
s
0.16
55
552
8
84
0.92
0.00
1.3
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
54
0.89
0.00
1.2
1.4
0.7
0.9
g/l
—
5
54
6
57
1.01
0.00
1.0
1.0
—
—
—
0
0
6
62
0.93
0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
65.6
—
0
5
0
8
0.00
-0.00
0.0
7.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_FOODDERMAT and mortality.

Females

Parameter HR [95% CI] p-value
L12_FOODDERMAT 1.166 [0.82, 1.66] 0.397
Birth year 0.994 [0.99, 1.0] 0.143

During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 20631 females with L12_FOODDERMAT died.

Males

Parameter HR [95% CI] p-value
L12_FOODDERMAT 1.004 [0.79, 1.28] 0.975
Birth year 0.99 [0.98, 1.0] 0.035

During the follow-up period (1.1.1998 — 31.12.2019), 84 out of 27933 males with L12_FOODDERMAT died.

Mortality risk

Mortality risk for people of age

years, who have L12_FOODDERMAT.

N-year risk Females Males
1 0.097% 0.229%
5 0.584% 1.365%
10 1.745% 3.324%
15 3.17% 6.496%
20 5.573% 10.774%

Relationships between endpoints

Index endpoint: L12_FOODDERMAT – Dermatitis due to ingested food

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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