blood coagulation disease: A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
184 |
4. Check minimum number of eventsNone |
184 |
5. Include endpoints |
913 |
6. Filter based on genotype QC (FinnGen only) |
913 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF2
Chronic Coagulation defects
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6363 | 4116 | 2218 |
| Only index persons | 5866 | 3942 | 1924 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.12 | 0.06 |
| Only index persons | 0.12 | 0.14 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 29.42 | 33.02 | 22.61 |
| Only index persons | 29.70 | 32.84 | 23.25 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 913 | 690 | 223 |
| Unadjusted period prevalence (%) | 0.20 | 0.24 | 0.10 |
| Median age at first event (years) | 37.68 | 35.84 | 43.39 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 822
- Matched controls
- 8218
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D68.0
ICD-10 Finland
Von Willebrand disease
+∞
323.0
429
*
D68.2
ICD-10 Finland
Hereditary deficiency of other clotting factors
+∞
321.6
287
*
126
Kela drug reimbursment
Chronic coagulation defects
+∞
178.8
165
*
B02AA02
ATC
tranexamic acid; systemic
9.5
168.3
428
842
D68.8
ICD-10 Finland
Other specified coagulation defects
47.1
123.7
151
39
D66
ICD-10 Finland
Hereditary factor VIII deficiency
+∞
86.0
81
*
D68.9
ICD-10 Finland
Coagulation defect, unspecified
157.5
69.1
72
5
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
30.8
67.9
91
33
B02BD02
ATC
coagulation factor VIII; parenteral, topical, urethral
+∞
35.7
34
*
2864A
ICD-9 Finland
Coagulation defects, von Willebrand's disease
+∞
34.6
33
*
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
46.6
33.1
40
9
B01AB04
ATC
dalteparin; parenteral
6.6
29.9
80
133
N02AX02
ATC
tramadol; systemic, rectal
2.4
29.7
373
2117
B01AA03
ATC
warfarin; systemic
3.4
29.6
159
535
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
5.1
26.3
86
183
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.2
26.0
152
542
B01AB05
ATC
enoxaparin; parenteral
2.4
25.2
268
1369
28630
ICD-8 Finland
Coagulation defects, Vascular haemophilia
+∞
25.1
24
*
EBA10
NOMESCO Finland
Surgical removal of tooth
2.9
24.7
175
707
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
6.7
24.6
64
102
N02BE01
ATC
paracetamol; systemic, rectal
2.6
23.3
714
5869
2860A
ICD-9 Finland
Coagulation defects, Congenital factor VIII disorder
+∞
22.0
21
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.0
21.1
88
238
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
7.8
20.7
48
65
D67
ICD-10 Finland
Hereditary factor IX deficiency
+∞
19.9
19
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
18.9
350
2225
M362, D66
ICD-10 Finland
NA
+∞
18.8
18
*
28600
ICD-8 Finland
Coagulation defects, Haemophilia
+∞
18.8
18
*
R04.0
ICD-10 Finland
Epistaxis
4.3
18.7
71
176
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
21.4
18.7
27
13
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
18.1
394
2651
M01AE01
ATC
ibuprofen; systemic, rectal
0.5
16.0
561
6663
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.9
15.6
300
1897
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
15.6
316
2037
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
15.4
227
1298
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
2.5
15.4
131
579
R42
ICD-10 Finland
Dizziness and giddiness
2.2
14.6
171
882
D68.4
ICD-10 Finland
Acquired coagulation factor deficiency
+∞
14.6
14
*
M36.2
ICD-10 Finland
Haemophilic arthropathy
+∞
14.6
14
*
D69.1
ICD-10 Finland
Qualitative platelet defects
152.6
14.5
15
*
O28.0
ICD-10 Finland
Abnormal haematological finding on antenatal screening of mother
36.7
14.5
18
5
H02AB06
ATC
prednisolone; systemic
1.8
14.4
371
2576
ZX120
NOMESCO Finland
Intravenous
2.8
14.0
93
357
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
13.8
102
416
D68.1
ICD-10 Finland
Hereditary factor XI deficiency
+∞
13.6
13
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
13.2
230
1386
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
12.8
166
891
M79.6
ICD-10 Finland
Pain in limb
1.8
12.8
298
1981
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
8.0
12.7
28
36
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
12.5
123
583
2BD06
NOMESCO Finland
NA
131.9
12.5
13
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
12.3
77
285
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
12.0
297
2000
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
12.0
227
1403
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
12.0
340
2389
R03AC02
ATC
salbutamol; inhalant
1.7
11.9
443
3366
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.9
11.9
196
1155
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
11.8
267
1746
R06.0
ICD-10 Finland
Dyspnoea
1.9
11.8
184
1059
J01DB01
ATC
cefalexin; oral
1.9
11.8
671
5781
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.3
11.6
119
574
R51.80
ICD-10 Finland
Headache
2.1
11.5
151
811
AA1AD
NOMESCO Finland
CT of head and brain
2.0
11.4
160
885
UJF32
NOMESCO Finland
Coloscopy
1.9
11.3
187
1098
Z31.5
ICD-10 Finland
Genetic counselling
2.9
11.3
70
257
N03AX16
ATC
pregabalin; oral
1.9
11.3
183
1067
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.5
11.2
90
384
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.0
11.1
35
73
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
11.1
219
1366
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
11.0
142
757
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
10.9
438
3367
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
10.5
182
1081
194
Kela drug reimbursment
Blood coagulation factor VIII and von Willebrand factor for the treatment of von Willebrand disease
+∞
10.4
10
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
10.4
181
1081
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
10.2
178
1060
N03AX12
ATC
gabapentin; oral
2.1
9.9
123
646
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
9.7
9.8
19
20
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
9.7
78
335
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
9.5
216
1401
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.3
9.4
24
39
B02BD06
ATC
von Willebrand factor and coagulation factor VIII in combination; parenteral, topical, urethral
+∞
9.4
9
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.2
9.4
48
156
Z71.8
ICD-10 Finland
Other specified counselling
1.7
9.4
209
1347
9981A
ICD-9 Finland
Other complications of procedures, not elsewhere classified, Haemorrhage or haematoma complicating a procedure
13.9
9.2
15
11
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.9
9.2
150
872
B18.2
ICD-10 Finland
Chronic viral hepatitis C
6.8
9.2
22
33
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
15.8
9.1
14
9
I80.20
ICD-10 Finland
Phlebitis and thrombophlebitis in the iliac vein
24.3
8.9
12
5
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
4.4
8.9
31
73
J01DA01
ATC
[U] cefalexin; systemic
1.6
8.9
499
4079
Z83.2
ICD-10 Finland
Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
50.5
8.7
10
*
D68.3
ICD-10 Finland
Haemorrhagic disorder due to circulating anticoagulants
50.5
8.7
10
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.4
8.6
74
329
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
8.5
145
855
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
8.3
341
2571
G43.9
ICD-10 Finland
Migraine, unspecified
2.3
8.3
77
355
K94
ICPC
Phlebitis/thrombophlebitis
6.6
8.2
20
31
4511A
ICD-9 Finland
Phlebitis and thrombophlebitis, Of deep vessels of lower extremities
14.6
8.2
13
9
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
8.2
79
371
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.7
8.1
55
215
P01AB01
ATC
metronidazole; oral, rectal
1.6
8.1
322
2404
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
8.0
149
904
G47.3
ICD-10 Finland
Sleep apnoea
1.8
7.9
140
834
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.2
7.9
77
364
J01FF01
ATC
clindamycin; systemic
1.6
7.8
210
1417
LCA06
NOMESCO Finland
Biopsy of endometrium
1.9
7.7
112
625
M25.5
ICD-10 Finland
Pain in joint
1.6
7.6
234
1638
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.8
7.6
48
180
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.0
7.5
94
494
J01CA04
ATC
amoxicillin; systemic
1.6
7.5
671
5994
D86.0
ICD-10 Finland
Sarcoidosis of lung
6.5
7.4
18
28
B28
ICPC
Limited function/disability (B)
80.8
7.4
8
*
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
5.7
7.4
20
36
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.5
7.4
57
238
K92.1
ICD-10 Finland
Melaena
3.2
7.4
37
120
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.4
7.4
63
279
A02BC02
ATC
pantoprazole; systemic
1.5
7.4
458
3754
K01.0
ICD-10 Finland
Embedded teeth
3.8
7.3
29
78
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
7.3
113
644
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
7.3
268
1953
D64.9
ICD-10 Finland
Anaemia, unspecified
2.4
7.3
58
249
B02BD04
ATC
coagulation factor IX; parenteral
+∞
7.3
7
*
28610
ICD-8 Finland
Coagulation defects, Christmas disease
+∞
7.3
7
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.6
7.3
31
89
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
7.2
139
849
M25.0
ICD-10 Finland
Haemarthrosis
7.4
7.2
16
22
K08.3
ICD-10 Finland
Retained dental root
2.5
7.2
53
217
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.7
7.2
46
174
S80.1
ICD-10 Finland
Contusion of other and unspecified parts of lower leg
3.5
7.2
32
95
J01FA10
ATC
azithromycin; systemic
1.5
7.2
496
4148
I87.0
ICD-10 Finland
Postthrombotic syndrome
20.2
7.1
10
5
M01AG02
ATC
tolfenamic acid; oral, rectal
1.7
7.1
146
910
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
7.1
184
1226
R50.9
ICD-10 Finland
Fever, unspecified
1.9
7.0
110
627
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
7.0
396
3166
ZXA10
NOMESCO Finland
Bilateral
1.8
7.0
129
780
SPAT1263
SPAT
Sampling
1.5
7.0
332
2559
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.5
7.0
52
216
R55
ICD-10 Finland
Syncope and collapse
2.1
6.9
72
352
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.9
6.8
39
137
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.2
6.8
71
346
N02AA05
ATC
oxycodone; systemic
2.0
6.7
82
429
N03AF01
ATC
carbamazepine; oral, rectal
2.9
6.7
39
140
G50.0
ICD-10 Finland
Trigeminal neuralgia
5.6
6.6
18
33
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.9
6.6
93
512
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.8
6.6
26
70
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
6.6
81
423
C01CA24
ATC
epinephrine; parenteral
2.1
6.6
68
331
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
6.6
127
778
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.6
255
1876
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.5
6.5
47
192
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
6.5
101
574
R01AD12
ATC
fluticasone furoate; nasal
1.5
6.5
263
1948
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.0
6.5
80
419
R4110
NOMESCO Finland
Physiotherapy
1.6
6.5
189
1297
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
6.5
104
600
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.2
6.4
64
304
C03CA01
ATC
furosemide; systemic
1.7
6.4
135
848
3AC01
NOMESCO Finland
NA
6.0
6.3
16
27
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
11.1
6.3
11
10
R60.0
ICD-10 Finland
Localized oedema
2.1
6.3
72
364
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
6.3
56
255
O991, D680
ICD-10 Finland
NA
+∞
6.3
6
*
2BDXX
NOMESCO Finland
NA
+∞
6.3
6
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
6.2
142
915
I80.9
ICD-10 Finland
Phlebitis and thrombophlebitis of unspecified site
6.3
6.2
15
24
C07AB07
ATC
bisoprolol; oral
1.5
6.2
264
1978
R31
ICD-10 Finland
Unspecified haematuria
2.2
6.1
56
259
N02AC04
ATC
dextropropoxyphene; oral
3.7
6.1
25
70
R23.3
ICD-10 Finland
Spontaneous ecchymoses
3.9
6.1
23
60
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
6.1
135
861
DKW00
NOMESCO Finland
Cauterisation of mucosa of nose
6.8
6.1
14
21
UJF30
NOMESCO Finland
Ileoscopy through colon
2.0
6.0
69
352
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
6.0
90
507
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
380
225
28.22
307.65
7.3
3.1
113.42
171.55
%
18.97
359
216
275
226
16.98
291.01
4.5
3.3
3.14
3.56
g/l
3.35
254
213
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
121
26
53.50
209.80
1.6
1.0
100.22
129.42
%
2.39
109
26
422
944
7.45
198.38
4.4
2.2
32.53
29.57
s
5.22
405
911
106
26
45.99
177.89
1.4
1.0
94.26
98.94
%
0.23
57
16
105
27
43.81
174.13
1.3
1.0
95.39
94.59
%
0.05
54
17
200
259
9.61
150.83
5.4
3.0
96.32
93.65
%
0.81
195
238
96
8
133.89
90.91
1.7
1.6
—
—
—
0
0
433
1756
3.79
85.08
7.3
3.6
93.03
94.77
%
0.58
416
1700
303
1025
3.93
76.70
5.0
3.8
0.81
0.82
mmol/l
0.34
295
965
399
1713
3.36
68.52
3.7
1.9
0.75
0.93
mg/l
1.12
292
1271
234
867
3.28
48.97
4.1
2.4
23.57
23.43
%
0.05
221
738
177
550
3.75
48.77
3.0
2.4
83.62
73.79
ml/min/173m2
3.12
135
216
46
0
+∞
48.36
1.5
0.0
51.10
—
%
—
40
0
484
2778
2.58
42.94
6.2
4.7
36.99
36.45
g/l
1.39
449
2608
238
955
3.02
42.86
4.0
2.3
2.44
2.42
g/l
0.23
226
875
249
1051
2.88
40.66
3.9
2.3
14.13
13.92
umol/l
0.18
238
964
253
1133
2.71
36.40
3.8
2.6
2.41
2.43
mmol/l
1.74
238
994
172
625
3.16
36.33
3.4
4.5
225.75
248.86
u/l
0.74
162
595
400
2284
2.34
33.49
3.7
3.2
2.35
2.35
mmol/l
0.08
365
2035
332
1767
2.38
32.50
3.5
2.2
2.85
2.86
mg/l
0.04
289
1518
166
628
3.01
32.47
3.4
3.0
1.70
1.76
%
0.28
150
564
504
3262
2.22
30.15
7.7
6.6
1.22
1.22
mmol/l
0.16
424
2783
462
2916
2.18
29.10
8.4
5.9
1.22
1.22
mmol/l
0.04
430
2659
718
5488
2.44
27.19
8.5
6.9
74.65
76.87
u/l
0.78
686
5157
524
3564
2.10
26.13
6.2
5.9
10.31
10.73
umol/l
0.24
499
3373
604
4348
2.15
25.73
9.3
8.8
4.04
3.98
e9/l
0.30
554
3820
534
3690
2.08
25.12
7.1
5.8
28.62
29.17
%
0.61
509
3465
527
3648
2.05
24.38
6.8
5.6
57.02
56.57
%
0.40
504
3433
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
63
157
4.24
23.16
5.7
4.2
0.31
0.38
u/ml
0.83
39
78
545
3972
1.92
20.02
6.1
4.6
6.36
6.50
mmol/l
0.68
521
3637
688
5489
2.03
18.59
5.0
3.9
9.73
10.52
mm/h
0.94
658
5123
522
3808
1.87
18.50
4.5
2.8
92.00
88.81
ug/l
0.18
493
3577
52
140
3.88
17.21
1.4
1.2
4.31
5.60
u/ml
0.26
26
57
51
139
3.83
16.59
1.4
1.2
2.82
3.21
u/ml
0.08
17
48
231
1363
1.93
15.37
2.6
2.5
6.22
7.05
e6/l
0.33
202
1183
310
2017
1.81
15.11
3.3
3.0
27.83
85.69
e6/l
1.00
249
1502
131
630
2.26
15.06
31.7
17.0
1.48
1.23
inr
—
10
102
286
1826
1.82
14.78
3.2
2.8
0.30
0.37
e6/l
0.43
230
1323
14
0
+∞
14.62
2.5
0.0
—
—
—
0
0
46
132
3.62
13.91
1.2
1.1
—
—
—
0
0
464
3490
1.67
12.84
5.3
3.9
—
—
—
0
0
12
0
+∞
12.53
1.4
0.0
—
—
—
0
0
842
7561
2.46
12.50
19.1
12.6
3.91
3.93
mmol/l
2.34
831
7354
840
7536
2.43
12.48
19.3
12.6
139.57
139.63
mmol/l
0.30
831
7349
849
7656
2.55
12.41
17.9
11.6
19.08
20.87
mg/l
0.86
722
5891
257
1707
1.70
11.05
3.0
2.1
—
—
—
0
0
102
504
2.15
10.88
5.9
3.3
1.22
1.23
mmol/l
0.36
94
429
346
2517
1.60
10.25
3.5
3.2
26.88
29.47
u/l
1.59
330
2403
11
10
11.12
10.18
1.2
1.1
14.92
18.75
umol/l
—
11
10
15
21
7.25
10.16
2.6
2.0
51.17
76.56
ug/l
0.53
15
21
406
3118
1.54
9.23
2.9
2.3
74.84
75.24
nmol/l
0.10
384
2856
752
6652
1.74
9.20
22.1
14.2
13.66
13.53
%
1.32
744
6531
299
2159
1.57
8.86
2.5
2.4
53.82
55.63
u/l
0.52
283
2007
322
2365
1.56
8.85
3.2
3.2
20.73
50.39
ng/l
0.98
173
1351
220
1479
1.64
8.76
2.8
3.1
1273.97
1042.91
ng/l
0.38
176
1219
181
1158
1.70
8.71
3.7
3.3
402.90
342.31
ng/l
0.12
120
757
777
6967
1.77
8.68
15.7
10.1
89.05
87.83
ml/min/173m2
0.82
691
5649
202
1339
1.65
8.48
1.3
1.3
33.33
13.27
u/ml
0.47
80
560
208
1398
1.63
8.24
1.4
1.3
27.85
28.56
iu/ml
0.03
60
460
343
2613
1.50
7.72
2.0
1.9
101.04
96.85
pmol/l
0.78
197
1397
259
1862
1.55
7.63
1.7
1.7
1.48
1.36
mmol/l
1.08
226
1614
57
258
2.29
7.54
1.5
2.0
—
—
—
0
0
860
8056
2.16
7.14
13.1
9.2
25.21
25.33
u/l
0.08
847
7830
120
722
1.76
7.13
2.4
2.0
359.21
373.00
nmol/l
0.39
112
669
21
56
3.81
7.11
1.2
1.1
—
—
—
0
0
133
828
1.71
7.00
8.8
6.1
1.07
1.07
mmol/l
0.07
127
768
154
997
1.66
6.99
2.1
1.8
—
—
—
0
0
164
1084
1.63
6.86
2.1
2.5
88.09
103.66
ug/g
0.46
122
861
572
4889
1.46
6.77
5.1
4.1
158.50
1317.41
e6/l
—
10
63
98
566
1.82
6.67
1.4
1.2
73.85
200.75
u/ml
2.11
89
519
111
675
1.73
6.35
2.0
1.7
—
—
—
0
0
449
3700
1.42
6.30
4.1
3.3
0.00
0.00
estimate
0.00
117
707
232
1689
1.50
6.28
3.2
2.5
1764.80
5733.66
umol/l
1.53
206
1490
54
259
2.15
6.25
1.6
1.6
0.22
0.24
g/l
0.89
54
243
691
6172
1.49
6.17
5.2
4.1
14.52
14.47
pmol/l
0.21
655
5754
262
1961
1.47
6.17
4.7
3.6
0.00
0.01
estimate
1.34
122
709
109
666
1.72
6.13
1.9
1.7
—
—
—
0
0
104
628
1.74
6.09
3.4
3.0
—
—
—
0
0
55
272
2.09
5.90
1.6
1.5
1.13
1.19
g/l
0.79
55
254
160
1097
1.56
5.68
2.8
2.4
0.63
0.99
e6/l
2.12
93
599
153
1039
1.57
5.66
2.9
2.6
2.92
3.24
e6/l
0.20
86
545
124
802
1.63
5.62
4.1
3.0
8.87
7.59
umol/l
0.15
106
693
250
1889
1.45
5.51
2.4
2.1
175.22
248.64
u/l
0.52
242
1785
34
141
2.47
5.51
3.6
3.6
58.35
56.49
%
0.34
34
141
232
1731
1.46
5.46
1.8
1.5
2.15
2.17
g/l
0.07
153
1076
33
137
2.46
5.35
3.1
3.4
4.29
4.15
e9/l
0.11
33
137
261
2005
1.42
5.22
1.4
1.3
0.62
1.78
u/ml
3.01
84
536
99
616
1.68
5.21
11.1
9.1
0.93
1.22
mmol/l
0.28
79
486
28
109
2.62
5.17
3.8
2.3
17.33
16.23
%
0.56
13
57
446
3761
1.36
5.04
4.1
3.3
0.00
0.01
estimate
0.80
120
698
91
562
1.69
4.93
3.3
3.5
4.48
4.57
pmol/l
0.35
81
492
20
67
3.03
4.85
1.7
2.1
691.22
727.26
e6/l
—
9
23
74
436
1.76
4.75
1.7
1.6
—
—
—
0
0
439
3720
1.35
4.68
5.4
4.5
0.00
0.00
estimate
0.50
123
715
57
319
1.84
4.35
1.7
1.6
—
—
—
0
0
13
36
3.65
4.21
1.1
1.1
1852.08
1589.39
miu/ml
0.36
13
36
75
460
1.69
4.19
2.7
2.9
66.69
67.21
g/l
0.28
69
422
45
237
1.95
4.13
1.2
1.2
45.02
15.12
u/ml
—
5
13
42
216
1.99
4.12
1.2
1.2
4.33
2.94
u/ml
—
6
24
767
7163
1.44
3.99
6.0
4.8
1.80
1.97
mu/l
0.52
724
6729
42
220
1.95
3.93
1.2
1.3
2.99
13.94
u/ml
—
8
40
97
646
1.56
3.91
2.4
2.4
236.67
108.32
u/l
0.25
87
540
44
237
1.90
3.80
1.5
2.1
1.38
1.45
g/l
0.21
38
208
18
66
2.76
3.77
1.9
1.7
33.56
32.15
pg
0.86
18
66
652
5956
1.33
3.69
3.8
3.5
—
—
—
0
0
83
541
1.59
3.68
2.2
2.2
3064.46
4154.45
u/l
0.22
30
224
67
414
1.67
3.67
2.9
3.0
190.02
146.35
ng/l
0.37
61
379
345
2898
1.31
3.65
4.4
3.3
—
—
—
0
0
888
8612
2.14
3.60
27.9
17.3
257.81
259.98
e9/l
0.42
882
8428
247
1987
1.33
3.54
3.4
3.2
7.59
7.78
mmol/l
0.26
210
1714
37
193
1.96
3.53
1.2
1.2
50.08
27.04
u/ml
—
6
18
888
8620
2.10
3.46
27.9
17.3
4.50
4.50
e12/l
0.11
882
8423
34
175
1.98
3.37
1.8
1.5
—
—
—
0
0
53
315
1.72
3.36
5.4
4.8
24.21
23.79
mmol/l
0.32
48
294
30
149
2.05
3.28
1.2
1.2
—
—
—
0
0
577
5243
1.27
3.07
3.6
3.0
44.11
40.28
u/l
0.58
541
5004
20
88
2.30
2.95
1.5
1.5
—
—
—
0
0
14
53
2.67
2.80
1.6
2.4
8.86
11.16
%
—
7
37
19
84
2.29
2.78
1.1
1.1
—
—
—
0
0
41
240
1.74
2.78
1.9
1.9
2.58
5.12
iu/l
2.74
17
90
77
529
1.50
2.74
4.0
4.0
89.40
74.66
ng/l
0.54
69
479
31
168
1.87
2.70
1.5
1.6
—
—
—
0
0
772
7330
1.34
2.67
4.6
3.9
4.69
4.75
mmol/l
0.96
725
6921
30
162
1.88
2.65
1.5
1.6
—
—
—
0
0
235
1947
1.28
2.63
1.8
1.6
—
—
—
0
0
60
396
1.55
2.58
1.8
1.7
—
—
—
0
0
9
25
3.63
2.58
2.4
2.4
—
—
—
0
0
27
142
1.93
2.58
1.4
1.7
—
—
—
0
0
58
381
1.56
2.55
1.7
1.4
—
—
—
0
0
5
7
7.18
2.55
1.6
1.9
—
—
—
0
0
6
11
5.48
2.54
2.5
2.5
—
—
—
0
0
22
108
2.06
2.53
1.4
1.6
—
—
—
0
0
18
82
2.22
2.48
1.1
1.1
—
—
—
0
0
13
51
2.57
2.45
1.9
2.5
—
—
—
0
0
37
219
1.72
2.45
2.8
1.7
3.36
3.82
g/l
1.72
31
161
37
219
1.72
2.45
2.8
1.7
6.91
7.47
g/l
1.42
32
172
37
219
1.72
2.45
2.8
1.7
—
—
—
0
0
18
83
2.19
2.42
1.1
1.1
—
—
—
0
0
18
83
2.19
2.42
1.1
1.1
—
—
—
0
0
18
83
2.19
2.42
1.1
1.1
—
—
—
0
0
138
1076
1.33
2.41
1.8
1.7
1147.24
1185.75
nmol/l
0.18
106
826
15
65
2.33
2.32
1.7
1.6
—
—
—
0
0
15
65
2.33
2.32
17.3
9.3
7.09
6.40
mmol/l
0.37
15
51
9
28
3.24
2.31
1.0
1.4
—
—
—
0
0
30
170
1.79
2.31
1.5
1.3
239.32
238.86
u/ml
0.00
19
101
18
85
2.14
2.30
1.2
1.1
1.33
1.42
g/l
0.34
18
77
31
178
1.77
2.29
1.5
1.2
—
—
—
0
0
184
1504
1.28
2.28
1.7
1.5
21.60
21.10
nmol/l
0.16
161
1317
28
157
1.81
2.23
1.7
1.8
0.00
0.00
g/l
0.00
28
146
23
122
1.91
2.17
1.5
1.5
—
—
—
0
0
737
7013
1.26
2.08
4.1
3.5
1.35
1.24
mmol/l
1.92
696
6584
17
82
2.09
2.08
1.1
1.1
—
—
—
0
0
27
154
1.78
2.06
2.4
2.8
—
—
—
0
0
7
20
3.52
2.06
1.0
1.1
—
—
—
0
0
7
20
3.52
2.06
1.0
1.1
89.14
96.00
%
—
7
20
763
7295
1.28
2.04
4.5
3.8
1.44
1.50
mmol/l
4.13
717
6862
16
76
2.12
2.03
1.6
1.6
—
—
—
0
0
61
429
1.45
1.99
2.3
2.4
6.94
6.99
ug/l
0.01
53
386
59
413
1.46
1.98
6.3
4.2
1.63
1.63
mmol/l
0.00
42
298
33
202
1.66
1.98
1.6
1.4
341.17
309.14
ug/g
0.35
20
113
77
567
1.39
1.96
5.6
4.5
2.28
1.77
mmol/l
0.73
67
445
19
98
1.96
1.96
1.4
1.3
—
—
—
0
0
25
142
1.78
1.94
1.2
1.1
—
—
—
0
0
5
11
4.56
1.94
2.6
1.6
—
—
—
0
0
8
27
2.98
1.94
1.0
1.3
—
—
—
0
0
774
7426
1.28
1.92
4.9
4.2
2.81
2.84
mmol/l
0.44
727
6968
26
150
1.75
1.92
1.8
1.5
100.43
108.31
u/ml
—
7
28
33
204
1.64
1.91
14.3
4.3
1.13
1.31
mmol/l
0.99
33
199
210
1781
1.23
1.88
4.5
4.1
11.36
9.56
mg/mmol
0.25
142
1133
31
190
1.65
1.86
9.3
4.3
8.05
8.76
kpa
1.41
31
179
23
130
1.79
1.83
1.3
1.3
—
—
—
0
0
23
130
1.79
1.83
1.3
1.3
—
—
—
0
0
5
12
4.18
1.82
1.8
1.8
—
—
—
0
0
8
29
2.77
1.79
1.0
1.3
—
—
—
0
0
8
29
2.77
1.79
1.0
1.3
—
—
—
0
0
14
67
2.11
1.76
1.7
1.3
—
—
—
0
0
23
133
1.75
1.71
1.2
1.1
—
—
—
0
0
38
253
1.52
1.65
1.5
1.3
—
—
—
0
0
7
25
2.81
1.65
1.0
1.4
—
—
—
0
0
7
25
2.81
1.65
1.1
1.2
—
—
—
0
0
11
49
2.26
1.64
1.8
1.4
13.86
23.46
ug/l
1.25
11
49
5
14
3.58
1.61
1.0
1.0
—
—
—
0
0
16
84
1.92
1.60
1.1
1.4
—
—
—
0
0
14
70
2.02
1.59
1.3
1.2
0.31
0.08
u/ml
—
8
24
43
298
1.46
1.56
2.0
1.8
—
—
—
0
0
198
1701
1.21
1.56
3.4
3.3
427.82
325.67
mg/l
0.11
133
1087
16
85
1.90
1.55
1.1
1.4
—
—
—
0
0
25
153
1.65
1.54
1.3
1.3
—
—
—
0
0
188
1609
1.21
1.54
4.6
3.5
1.02
1.02
kg/l
0.30
26
210
10
44
2.29
1.53
1.0
1.2
—
—
—
0
0
41
283
1.47
1.52
11.6
9.6
24.02
24.34
mmol/l
0.38
41
267
5
15
3.35
1.52
1.0
1.2
—
—
—
0
0
9
37
2.45
1.48
1.7
2.9
560.78
610.59
u/ml
—
9
37
19
109
1.76
1.47
1.6
1.3
—
—
—
0
0
11
52
2.13
1.45
1.2
1.4
—
—
—
0
0
13
66
1.98
1.44
1.0
1.1
—
—
—
0
0
9
39
2.32
1.43
3.0
2.4
31.33
28.08
umol/l
—
9
39
41
288
1.44
1.41
1.6
1.4
13.47
9.66
u/l
0.53
31
232
7
29
2.42
1.39
1.0
1.2
—
—
—
0
0
16
90
1.79
1.33
1.6
1.5
—
—
—
0
0
12
61
1.98
1.33
1.2
1.2
—
—
—
0
0
122
1016
1.23
1.32
1.5
1.7
1.50
1.38
%
0.60
103
924
15
83
1.82
1.32
1.0
1.2
—
—
—
0
0
12
62
1.95
1.28
1.2
1.3
—
—
—
0
0
12
62
1.95
1.28
3.6
1.6
—
—
—
0
0
15
84
1.80
1.27
1.1
1.4
—
—
—
0
0
26
170
1.54
1.27
17.7
4.2
3.82
3.81
mmol/l
0.06
26
155
65
505
1.31
1.24
1.3
1.4
—
—
—
0
0
13
70
1.87
1.24
1.2
1.5
—
—
—
0
0
35
246
1.44
1.23
1.4
1.1
—
—
—
0
0
10
49
2.05
1.22
1.4
2.8
—
—
—
0
0
734
7088
1.18
1.22
4.4
3.9
5.81
5.75
mmol/l
0.42
672
6585
5
19
2.64
1.21
3.4
5.3
—
—
—
0
0
684
6570
1.16
1.20
5.6
4.9
38.70
38.67
mmol/mol
0.03
628
6211
171
1486
1.19
1.20
2.2
2.2
—
—
—
0
0
15
86
1.76
1.19
1.1
1.4
—
—
—
0
0
6
26
2.32
1.19
1.5
1.5
10.46
8.20
ug/l
—
6
26
6
26
2.32
1.19
1.0
1.1
90.17
101.94
nmol/l
—
6
20
15
87
1.74
1.15
1.1
1.4
—
—
—
0
0
15
87
1.74
1.15
1.1
1.4
—
—
—
0
0
34
242
1.42
1.13
1.2
1.2
—
—
—
0
0
36
260
1.40
1.11
1.2
1.3
—
—
—
0
0
87
714
1.24
1.10
1.2
1.2
177.44
150.89
iu/ml
0.22
33
294
15
90
1.68
1.04
1.2
1.1
—
—
—
0
0
5
22
2.28
1.03
1.2
1.0
—
—
—
0
0
17
107
1.60
1.00
1.5
1.5
—
—
—
0
0
71
577
1.25
0.99
2.8
4.2
3.00
39.16
ug/l
1.51
49
466
33
241
1.38
0.98
1.2
1.2
—
—
—
0
0
15
92
1.64
0.97
1.2
1.1
—
—
—
0
0
17
108
1.58
0.97
1.1
1.1
—
—
—
0
0
751
7305
1.16
0.94
19.5
12.5
40.05
39.90
%
0.23
596
5799
11
62
1.78
0.94
1.2
1.3
—
—
—
0
0
11
62
1.78
0.94
1.1
1.0
—
—
—
0
0
6
30
2.01
0.87
1.0
1.3
—
—
—
0
0
6
30
2.01
0.87
1.2
1.5
—
—
—
0
0
36
274
1.33
0.85
2.5
1.8
—
—
—
0
0
23
162
1.43
0.85
1.1
1.4
—
—
—
0
0
8
45
1.78
0.84
1.1
1.6
—
—
—
0
0
13
81
1.61
0.81
1.2
1.1
—
—
—
0
0
150
1337
1.15
0.79
2.2
2.0
—
—
—
0
0
6
33
1.82
0.79
1.5
1.8
—
—
—
0
0
6
33
1.82
0.79
1.5
1.8
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
8
48
1.67
0.79
1.1
1.1
—
—
—
0
0
9
53
1.70
0.75
1.1
1.1
—
43.20
—
0
5
9
54
1.67
0.74
1.1
1.1
—
61.88
—
0
8
22
159
1.39
0.73
1.1
1.4
—
—
—
0
0
10
60
1.67
0.72
1.3
1.4
—
—
—
0
0
5
26
1.93
0.70
1.0
1.3
—
—
—
0
0
5
26
1.93
0.70
1.6
1.3
—
—
—
0
0
5
26
1.93
0.70
1.0
1.3
—
—
—
0
0
87
752
1.17
0.70
6.5
6.0
—
—
—
0
0
72
613
1.19
0.69
1.5
1.4
19.80
25.34
iu/l
1.07
61
515
46
375
1.24
0.68
1.2
1.3
216.31
228.58
miu/ml
0.09
23
192
34
270
1.27
0.63
2.8
3.7
1.42
1.21
%
0.49
34
270
10
63
1.59
0.62
1.6
1.6
—
—
—
0
0
10
63
1.59
0.62
1.6
1.6
—
—
—
0
0
10
63
1.59
0.62
1.6
1.6
—
—
—
0
0
24
182
1.33
0.62
1.8
1.5
0.31
0.37
nmol/l
0.34
19
150
81
706
1.16
0.61
2.1
1.7
—
—
—
0
0
15
106
1.42
0.58
1.2
1.3
—
—
—
0
0
6
35
1.72
0.57
1.0
1.0
—
—
—
0
0
31
248
1.26
0.56
2.5
1.7
—
—
—
0
0
21
159
1.33
0.55
1.8
1.8
—
—
—
0
0
101
904
1.13
0.54
2.2
1.8
—
—
—
0
0
9
63
1.43
0.52
1.3
1.2
—
—
—
0
0
6
41
1.47
0.50
1.0
1.1
—
—
—
0
0
7
45
1.56
0.49
1.1
1.1
—
—
—
0
0
22
172
1.29
0.48
3.0
2.6
6.08
6.86
umol/l
0.16
17
126
7
47
1.49
0.47
1.0
1.0
—
—
—
0
0
150
1388
1.10
0.46
1.9
1.7
472.67
28109884.81
pmol/l
1.57
123
1206
7
51
1.38
0.44
1.1
2.2
—
—
—
0
0
5
31
1.62
0.43
1.0
1.0
—
—
—
0
0
15
113
1.33
0.43
1.4
1.5
—
—
—
0
0
8
56
1.43
0.42
2.0
1.7
0.87
0.99
g/l
—
8
56
10
70
1.43
0.42
1.5
1.3
—
—
—
0
0
13
96
1.36
0.41
1.3
1.3
0.65
0.52
nmol/l
1.04
13
91
0
16
0.00
0.41
0.0
1.8
—
7.58
—
0
11
10
71
1.41
0.39
1.0
1.8
43.80
58.06
%
—
5
47
0
19
0.00
0.39
0.0
3.4
—
1.23
—
0
19
76
838
0.90
0.37
1.5
1.6
—
—
—
0
0
85
777
1.10
0.35
4.2
3.9
30.08
31.98
%
0.85
63
558
43
377
1.15
0.34
1.7
1.5
—
—
—
0
0
28
237
1.19
0.34
1.2
1.4
133.50
113.35
pmol/l
0.10
28
231
19
155
1.23
0.32
1.2
1.1
0.76
2.48
u/ml
—
8
79
18
146
1.24
0.32
1.3
1.7
2432.38
16298.06
e6/l
—
8
108
32
278
1.16
0.30
5.7
3.8
25.99
25.05
mmol/l
0.87
32
271
7
56
1.25
0.29
1.3
1.4
—
—
—
0
0
7
56
1.25
0.29
1.4
1.0
—
—
—
0
0
39
345
1.14
0.29
1.7
1.6
—
—
—
0
0
69
635
1.09
0.27
2.9
2.7
0.68
0.74
ug/l
0.24
45
388
9
76
1.19
0.24
1.1
1.2
—
—
—
0
0
11
87
1.27
0.24
1.6
1.5
—
—
—
0
0
6
84
0.71
0.24
1.2
1.4
—
—
—
0
0
31
349
0.88
0.24
1.8
1.9
—
—
—
0
0
36
400
0.90
0.23
1.5
1.4
—
—
—
0
0
5
40
1.25
0.22
1.2
1.6
—
—
—
0
0
5
40
1.25
0.22
1.2
1.6
—
—
—
0
0
5
40
1.25
0.22
3.0
1.8
—
77.80
%
—
0
5
5
40
1.25
0.22
1.2
1.6
—
—
—
0
0
5
40
1.25
0.22
1.2
1.6
—
—
—
0
0
5
42
1.19
0.21
2.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
29.03
—
0
9
76
714
1.07
0.20
1.6
1.5
—
—
—
0
0
19
218
0.87
0.19
1.2
1.1
0.12
2.34
u/ml
—
8
94
55
513
1.08
0.18
1.1
1.0
—
—
—
0
0
5
70
0.71
0.16
1.2
2.6
105.20
106.01
mmol/l
—
5
70
35
381
0.92
0.16
1.5
1.7
4.88
4.75
mg/l
0.02
24
266
16
139
1.15
0.16
3.6
3.8
40.90
27.66
mg/l
—
10
90
23
209
1.10
0.13
2.9
3.1
2335.33
1682.06
u/ml
0.10
18
184
15
167
0.90
0.10
1.3
1.1
—
—
—
0
0
5
48
1.04
0.09
1.6
1.5
0.60
5.16
u/field
—
5
39
6
55
1.09
0.09
2.2
2.2
—
—
—
0
0
6
73
0.82
0.07
2.3
1.9
—
—
—
0
0
86
882
0.97
0.07
3.8
4.0
25.27
21.59
%
1.04
40
371
17
183
0.93
0.06
1.2
1.3
—
—
—
0
0
175
1776
0.98
0.06
1.6
1.5
—
—
—
0
0
113
1112
1.02
0.04
4.4
4.4
1.95
2.22
ug/l
0.25
100
1005
27
260
1.04
0.03
1.7
1.5
—
—
—
0
0
13
138
0.94
0.02
1.2
1.1
166.29
3512.74
iu/ml
—
7
36
46
467
0.98
0.01
1.6
1.4
—
—
—
0
0
39
384
1.02
0.00
1.6
1.4
—
—
—
0
0
38
384
0.99
0.00
1.6
1.4
—
—
—
0
0
30
302
0.99
0.00
1.9
1.7
—
—
—
0
0
42
421
1.00
0.00
1.5
1.5
—
—
—
0
0
11
113
0.97
0.00
3.1
1.6
133.18
207.57
pmol/l
1.25
11
107
20
201
0.99
0.00
1.8
1.7
—
—
—
0
0
38
383
0.99
0.00
1.6
1.4
—
—
—
0
0
39
385
1.01
0.00
1.6
1.4
—
—
—
0
0
16
165
0.97
0.00
2.7
1.5
39.69
40.26
nmol/l
0.04
16
160
0
5
0.00
0.00
0.0
1.2
—
8.37
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
5.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
1.91
—
0
7
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
6
60
1.00
0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
5.22
—
0
6
5
50
1.00
0.00
1.6
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_COAGDEF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_COAGDEF | 1.541 [1.28, 1.85] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.136 |
During the follow-up period (1.1.1998 — 31.12.2019), 184 out of 3408 females with D3_COAGDEF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_COAGDEF | 1.698 [1.39, 2.07] | < 0.001 |
| Birth year | 0.985 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 193 out of 1530 males with D3_COAGDEF died.
Mortality risk
Mortality risk for people of age
years, who have D3_COAGDEF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.133% | 0.349% |
| 5 | 0.891% | 1.949% |
| 10 | 2.227% | 4.778% |
| 15 | 4.197% | 8.71% |
| 20 | 7.44% | 14.826% |
Relationships between endpoints
↥Index endpoint: D3_COAGDEF – Chronic Coagulation defects
GWS hits: 10
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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