alcohol withdrawal delirium: An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include confusion; delusions; vivid hallucinations; tremor; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)
Mental and behavioural disorders due to use of volatile solvents
DOID EFO Endpoint Browser PheWeb
F5_SOLVENT
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
107 |
4. Check minimum number of eventsNone |
107 |
5. Include endpointsNone |
107 |
6. Filter based on genotype QC (FinnGen only) |
107 |
Control definitions (FinnGen only)
- Control exclude
- F5_SUBSNOALCO
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F10-F19
- Name in latin
- Perturbationes mentis et modi se gerendi ex usu solventium volatilium
Similar endpoints
↥List of similar endpoints to
Mental and behavioural disorders due to use of volatile solvents
based on the number of shared cases.
Similar with more cases:
- Substance use, excluding alcohol
- Substance abuse, excluding more controls
- Substance abuse
- Mental and behavioural disorders due to psychoactive substance use
- Any mental disorder
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1225 | 317 | 902 |
| Only index persons | 1060 | 291 | 769 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.01 | 0.03 |
| Only index persons | 0.02 | 0.01 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 28.99 | 26.78 | 29.71 |
| Only index persons | 28.18 | 26.16 | 28.94 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 107 | 39 | 68 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.03 |
| Median age at first event (years) | 28.22 | 25.49 | 29.79 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 97
- Matched controls
- 967
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B18.2
ICD-10 Finland
Chronic viral hepatitis C
213.5
40.2
39
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
31.3
34.5
47
28
T36
ICD-10 Finland
Poisoning by systemic antibiotics
37.5
33.6
43
20
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
+∞
29.7
27
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
39.9
28.9
36
14
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
+∞
28.5
26
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
20.0
28.2
45
40
P19
ICPC
Drug abuse
+∞
27.4
25
*
F18.1
ICD-10 Finland
Mental and behavioural disorders due to use of volatile solvents, harmful use
+∞
26.2
24
*
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
+∞
26.2
24
*
N05AH03
ATC
olanzapine; systemic
19.4
25.8
41
35
N05AH04
ATC
quetiapine; oral
11.8
25.5
57
104
N07BB01
ATC
disulfiram; oral
30.3
22.6
30
14
F19.21
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances currently independent but staying in a controlling environment
+∞
21.7
20
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
21.1
21.3
32
22
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
12.1
20.2
40
53
P15
ICPC
Chronic alcohol abuse
44.8
20.0
24
7
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
+∞
19.4
18
*
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
+∞
18.3
17
*
F18.20
ICD-10 Finland
Dependence relationship caused by volatile solvents currently independent
+∞
18.3
17
*
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
32.9
17.9
23
9
N05BA01
ATC
diazepam; systemic, rectal
11.5
17.7
35
45
N05AX08
ATC
risperidone; systemic
12.6
16.2
30
33
3046A
ICD-9 Finland
Drug dependence, Other specified drug dependence
+∞
16.1
15
*
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
+∞
16.1
15
*
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
+∞
16.1
15
*
Z72.2
ICD-10 Finland
Drug use
+∞
16.1
15
*
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
35.4
15.9
20
7
N05AH02
ATC
clozapine; systemic
29.3
15.9
21
9
N03AE01
ATC
clonazepam; systemic
23.2
15.6
22
12
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
+∞
15.0
14
*
F15.5
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, psychotic disorder
+∞
15.0
14
*
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
+∞
15.0
14
*
F10.20
ICD-10 Finland
Alcohol dependence currently independent
25.8
14.0
19
9
F10.25
ICD-10 Finland
Alcohol dependence continuous use
31.1
14.0
18
7
F11.21
ICD-10 Finland
Addiction-indiced dependence caused by opiates currently independent but staying in controlling environment
+∞
13.9
13
*
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
+∞
13.9
13
*
P18
ICPC
Medication abuse
161.7
13.8
14
*
N06AX11
ATC
mirtazapine; oral
5.5
13.6
52
167
F10.09
ICD-10 Finland
Alcohol intoxication UNS
27.2
13.5
18
8
P16
ICPC
Acute alcohol abuse
29.0
13.0
17
7
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
80.8
13.0
14
*
F18.29
ICD-10 Finland
Dependence caused by volatile solvents UNS
+∞
12.8
12
*
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
19.3
12.8
19
12
N05AA02
ATC
levomepromazine; systemic
15.4
12.3
20
16
N05BA04
ATC
oxazepam; oral
5.4
11.9
43
125
N05BA12
ATC
alprazolam; oral
9.9
11.8
24
31
T40.6
ICD-10 Finland
Poisoning: Other and unspecified narcotics
+∞
11.7
11
*
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
7.1
11.6
30
57
N06AB04
ATC
citalopram; systemic
5.9
11.5
36
88
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
32.3
11.1
14
5
N05CD07
ATC
temazepam; oral
12.8
10.9
19
18
F32.9
ICD-10 Finland
Depressive episode, unspecified
6.1
10.9
32
72
AA1AD
NOMESCO Finland
CT of head and brain
6.3
10.8
31
67
F20.9
ICD-10 Finland
Schizophrenia, unspecified
15.5
10.6
17
13
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
37.1
10.6
13
*
F18.9
ICD-10 Finland
Mental and behavioural disorders due to use of volatile solvents, unspecified mental and behavioural disorder
+∞
10.6
10
*
F19.26
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances periodic addiction
+∞
10.6
10
*
F13.1
ICD-10 Finland
Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
+∞
10.6
10
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
10.6
10.4
20
23
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
19.4
10.3
15
9
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
19.4
10.3
15
9
F20.39
ICD-10 Finland
Undifferentiated schizophrenia UNS
45.0
10.2
12
*
X57
ICD-10 Finland
Unspecified privation
45.0
10.2
12
*
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
20.1
9.7
14
8
A46
ICD-10 Finland
Erysipelas
7.2
9.7
24
42
N05BA02
ATC
chlordiazepoxide; systemic
110.3
9.6
10
*
SPAT1275
SPAT
Drug rehabilitation and replacement therapy of opioid-dependent person
110.3
9.6
10
*
T40.9
ICD-10 Finland
Poisoning: Other and unspecified psychodysleptics [hallucinogens]
+∞
9.5
9
*
F19.9
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, unspecified mental and behavioural disorder
+∞
9.5
9
*
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
+∞
9.5
9
*
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
+∞
9.5
9
*
F19.00
ICD-10 Finland
Intoxication caused by several drugs in combination or by other psychoactive substances uncomplicated
+∞
9.5
9
*
K04.5
ICD-10 Finland
Chronic apical periodontitis
4.4
9.4
41
139
EBA30
NOMESCO Finland
Excision of root of tooth
17.9
9.4
14
9
F10.24
ICD-10 Finland
Alcohol depence active use
18.5
8.8
13
8
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
30.6
8.7
11
*
Y04.9
ICD-10 Finland
Assault by bodily force by unknown person
98.2
8.6
9
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.2
8.5
28
70
P72
ICPC
Schizophrenia
16.4
8.5
13
9
F11.20
ICD-10 Finland
Addiction-induced dependence caused by opiates currently independent
+∞
8.4
8
*
T65.9
ICD-10 Finland
Toxic effect: Toxic effect of unspecified substance
+∞
8.4
8
*
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
+∞
8.4
8
*
F18.00
ICD-10 Finland
Intoxication caused by volatile solvents uncomplicated
+∞
8.4
8
*
N05CF01
ATC
zopiclone; oral
4.1
8.4
38
131
N06AX16
ATC
venlafaxine; oral
4.9
8.4
29
77
F61.0
ICD-10 Finland
Mixed personality disorders
19.3
8.3
12
7
SPAT1265
SPAT
Breathalyser
36.7
8.2
10
*
F60.2
ICD-10 Finland
Dissocial personality disorder
36.7
8.2
10
*
L17
ICPC
Foot/toe symptom/complaint
4.5
8.2
32
96
N03AG01
ATC
valproic acid; systemic, rectal
8.3
7.9
17
24
N05AD01
ATC
haloperidol; systemic
11.5
7.8
14
14
C07AA05
ATC
propranolol; systemic
4.4
7.8
31
94
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
27.5
7.7
10
*
F99
ICD-10 Finland
Mental disorder, not otherwise specified
15.0
7.6
12
9
F12.1
ICD-10 Finland
Mental and behavioural disorders due to use of cannabinoids, harmful use
86.4
7.5
8
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.7
7.5
27
74
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
+∞
7.4
7
*
F19.59
ICD-10 Finland
Psychotic disorder caused by several drugs in combination and by other psychoactive substances UNS
+∞
7.4
7
*
F19.30
ICD-10 Finland
Withdrawal symptoms caused by several drugs in combination and by other psychoactive substances uncomplicated
+∞
7.4
7
*
F13.20
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent
+∞
7.4
7
*
F19.09
ICD-10 Finland
Intoxication caused by several drugs in combination and by other psychoactive substances UNS
+∞
7.4
7
*
F20
ICD-10 Finland
Schizophrenia
32.7
7.3
9
*
N05AF03
ATC
chlorprothixene; systemic
12.2
7.0
12
11
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
12.2
7.0
12
11
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
12.2
7.0
12
11
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
43.2
6.9
8
*
Y07
ICD-10 Finland
Other maltreatment
43.2
6.9
8
*
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
24.5
6.8
9
*
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
13.6
6.8
11
9
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
3.1
6.7
64
370
SPAT1247
SPAT
Outpatient detoxication and monitoring
74.5
6.5
7
*
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
74.5
6.5
7
*
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
74.5
6.5
7
*
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
12.2
6.5
11
10
N06AX12
ATC
bupropion; oral
5.4
6.4
19
42
KMAK
NOMESCO Finland
NA
3.2
6.4
71
450
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
28.7
6.3
8
*
SPAT1272
SPAT
Drug screening
+∞
6.3
6
*
F15.0
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, acute intoxication
+∞
6.3
6
*
Z03
ICPC
Housing/neighbourhood problem
+∞
6.3
6
*
F19.2
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, dependence syndrome
+∞
6.3
6
*
F11.30
ICD-10 Finland
Withdrawal symptoms caused by opiates uncomplicated
+∞
6.3
6
*
F05.9
ICD-10 Finland
Delirium, unspecified
+∞
6.3
6
*
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
+∞
6.3
6
*
F15.3
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, withdrawal state
+∞
6.3
6
*
F23.99
ICD-10 Finland
Acute and transient psychosis, unspecified UNS
+∞
6.3
6
*
WX730
NOMESCO Finland
Conventional respirator
+∞
6.3
6
*
N03AX16
ATC
pregabalin; oral
4.4
6.3
23
64
T74.1
ICD-10 Finland
Physical abuse
13.7
6.2
10
8
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
11.1
6.2
11
11
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
11.1
6.2
11
11
WX290
NOMESCO Finland
Other blockade of nerve
3.0
6.0
66
403
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
34
6
81.80
31.34
2.0
1.2
—
—
—
0
0
20
14
17.34
22.53
30.8
16.0
1344.5
1133.6
nmol/l
0.40
20
14
17
10
20.02
20.73
2.7
1.0
—
—
—
0
0
25
47
6.64
13.52
1.6
1.4
—
—
—
0
0
19
29
7.75
12.37
11.3
3.5
26.1
24.0
mmol/l
1.42
19
29
26
59
5.50
11.47
6.1
2.5
—
—
—
0
0
80
453
4.04
9.59
24.2
9.2
4.5
4.1
e9/l
0.78
71
405
59
276
3.54
9.53
4.7
4.6
35.6
38.0
g/l
1.99
54
264
59
286
3.37
8.82
7.6
5.4
1.2
1.2
mmol/l
0.81
52
244
76
430
3.65
8.82
9.2
3.6
6.9
6.6
mmol/l
0.46
71
394
16
32
5.70
7.94
13.2
6.3
0.7
0.7
%
0.26
16
32
16
33
5.53
7.69
13.2
6.2
1.7
2.0
%
0.19
16
33
46
229
2.77
6.05
3.3
2.7
—
—
—
0
0
21
79
3.06
4.48
5.7
5.6
1.0
1.0
mmol/l
0.33
21
74
12
31
4.23
4.39
1.7
1.1
—
—
—
0
0
36
186
2.41
4.14
3.1
2.4
0.5
0.2
e6/l
0.47
25
139
40
220
2.31
3.98
1.6
1.7
107.8
98.8
pmol/l
0.43
26
121
29
145
2.37
3.54
1.6
1.8
3.9
2.8
mg/l
0.55
24
124
77
569
2.26
3.53
3.6
3.7
14.6
14.7
pmol/l
0.08
71
530
22
98
2.57
3.41
2.6
2.3
7.3
1.0
e6/l
—
8
49
24
116
2.38
3.13
2.3
2.4
—
—
—
0
0
13
46
3.08
3.04
1.9
1.7
—
—
—
0
0
10
31
3.46
2.85
5.2
2.4
1.5
2.0
%
—
10
31
56
389
1.92
2.78
3.3
2.8
0.0
0.0
estimate
0.00
11
71
25
131
2.19
2.69
1.4
1.5
20.5
20.0
nmol/l
0.06
25
115
35
209
2.00
2.69
2.9
2.2
—
—
—
0
0
55
383
1.90
2.68
4.5
3.9
0.0
0.0
estimate
0.00
11
75
20
97
2.31
2.57
1.8
2.3
—
—
—
0
0
55
387
1.87
2.57
3.4
2.7
0.0
0.0
estimate
0.00
11
74
13
53
2.65
2.38
2.7
2.6
3835.1
97.3
u/l
—
5
20
6
13
4.82
2.30
1.3
1.0
—
—
—
0
0
6
13
4.82
2.30
1.3
1.0
—
—
—
0
0
17
81
2.31
2.27
1.6
1.5
—
—
—
0
0
36
229
1.86
2.25
3.3
2.3
—
—
—
0
0
17
82
2.28
2.21
1.7
1.6
—
—
—
0
0
21
113
2.07
2.10
1.8
1.8
—
—
—
0
0
5
11
4.71
1.96
1.2
1.0
—
—
—
0
0
20
110
2.01
1.89
2.7
2.2
3.0
0.7
e6/l
—
6
61
90
776
2.01
1.88
17.8
8.2
104.0
96.2
ml/min/173m2
2.68
75
633
8
31
2.71
1.69
1.9
1.7
—
—
—
0
0
6
19
3.28
1.68
2.2
2.7
—
—
—
0
0
6
19
3.28
1.68
1.2
1.1
—
—
—
0
0
25
156
1.79
1.62
2.6
1.8
—
—
—
0
0
6
22
2.83
1.45
1.5
1.3
—
—
—
0
0
35
247
1.62
1.45
3.2
2.5
54.8
26.8
ng/l
0.27
20
128
19
126
1.62
1.00
2.3
3.0
18.0
104.1
ng/l
—
10
79
28
207
1.48
0.92
3.7
2.7
0.0
0.0
estimate
0.49
11
74
8
131
0.58
0.80
2.8
2.1
0.4
0.6
ug/l
—
8
59
42
345
1.36
0.76
3.8
3.3
—
—
—
0
0
5
26
1.97
0.71
1.2
2.6
172.2
161.7
%
—
5
26
5
27
1.89
0.69
1.2
2.2
3.9
3.4
g/l
—
5
27
11
71
1.61
0.65
7.5
7.5
—
—
—
0
0
31
249
1.34
0.64
1.6
1.6
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
9.6
—
0
9
0
22
0.00
0.60
0.0
1.2
—
4.8
—
0
13
24
188
1.36
0.58
1.3
1.7
0.7
1.0
mg/l
0.62
14
138
7
47
1.52
0.48
1.0
1.4
—
—
—
0
0
13
171
0.73
0.43
3.8
2.6
7.9
20.3
%
—
6
52
5
32
1.59
0.43
6.6
2.8
51.3
57.1
%
—
5
32
0
15
0.00
0.41
0.0
3.0
—
1.0
—
0
15
0
15
0.00
0.41
0.0
3.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
7.4
—
0
11
0
18
0.00
0.40
0.0
1.2
—
94.1
—
0
18
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
35
309
1.20
0.33
3.4
2.6
—
—
—
0
0
11
136
0.79
0.25
1.5
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
0.0
—
0
11
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
0.0
—
0
11
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
3.6
—
15.2
—
0
12
0
13
0.00
0.21
0.0
1.8
—
7.2
—
0
6
0
13
0.00
0.21
0.0
3.2
—
10.4
—
0
13
0
14
0.00
0.20
0.0
3.1
—
0.0
—
0
14
85
833
1.10
0.10
4.3
3.6
2.6
2.9
mmol/l
2.55
80
791
8
74
1.09
0.07
1.4
1.9
274.5
362.7
nmol/l
—
8
69
23
217
1.08
0.06
2.4
2.8
1.3
1.5
ug/l
0.29
17
201
76
766
0.97
0.00
3.8
3.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
50.0
—
0
7
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.3
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
1190.2
—
0
6
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
178.2
—
0
6
0
6
0.00
0.00
0.0
1.7
—
898.3
—
0
6
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint F5_SOLVENT and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_SOLVENT | 5.861 [3.8, 9.04] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 151 out of 599 males with F5_SOLVENT died.
Mortality risk
Mortality risk for people of age
years, who have F5_SOLVENT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 1.15% |
| 5 | No data | 6.035% |
| 10 | No data | 15.889% |
| 15 | No data | 27.945% |
| 20 | No data | 43.88% |
Relationships between endpoints
↥Index endpoint: F5_SOLVENT – Mental and behavioural disorders due to use of volatile solvents
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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