No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
252 |
4. Check minimum number of eventsNone |
252 |
5. Include endpointsNone |
252 |
6. Filter based on genotype QC (FinnGen only) |
247 |
Control definitions (FinnGen only)
- Control exclude
- H7_LIDLACRIMALORBIT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H05
- Name in latin
- Inflammatio orbitae acuta
Similar endpoints
↥List of similar endpoints to
Acute inflammation of orbit
based on the number of shared cases.
Similar with more cases:
- Disorders of orbit
- Disorders of eyelid, lacrimal system and orbit
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2945 | 1284 | 1650 |
| Only index persons | 2527 | 1123 | 1404 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.05 |
| Only index persons | 0.05 | 0.04 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 24.56 | 30.24 | 19.99 |
| Only index persons | 23.68 | 29.27 | 19.21 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 247 | 135 | 112 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | 46.01 | 45.33 | 46.84 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 252
- Matched controls
- 2520
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H05.0
ICD-10 Finland
Acute inflammation of orbit
+∞
256.0
200
*
H00.03
ICD-10 Finland
Preseptal cellulite in the eyelid
132.6
42.3
44
*
3760A
ICD-9 Finland
Disorders of the orbit, Acute inflammation of orbit
+∞
33.0
31
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
8.4
25.7
36
49
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
10.8
25.5
29
30
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
9.5
21.0
26
30
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
79.8
20.0
22
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.9
19.6
74
244
H01.0
ICD-10 Finland
Blepharitis
7.3
19.2
30
46
UDH02
NOMESCO Finland
Rhinopharyngoscopy
6.1
18.2
34
63
CAA00
NOMESCO Finland
Puncture of orbital abscess
+∞
15.8
15
*
H57.1
ICD-10 Finland
Ocular pain
7.3
15.6
24
36
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
+∞
13.7
13
*
H05.2
ICD-10 Finland
Exophthalmic conditions
+∞
13.7
13
*
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
5.1
13.0
29
63
Z3229
NOMESCO Finland
Other healthcare associate professional
4.6
12.7
32
77
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
+∞
12.6
12
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.6
12.5
110
572
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
10.4
12.0
23
24
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.7
11.7
90
436
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
+∞
11.5
11
*
36900
ICD-8 Finland
Other inflammatory diseases of eye, Abscessus orbitae
+∞
11.5
11
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
4.3
11.4
31
79
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
11.2
80
372
H02AB06
ATC
prednisolone; systemic
2.5
11.1
130
762
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
29.5
10.8
14
5
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
4.4
10.5
28
70
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
+∞
10.5
10
*
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
+∞
10.5
10
*
H05.9
ICD-10 Finland
Disorder of orbit, unspecified
+∞
10.5
10
*
H04.10
ICD-10 Finland
Dry eye syndrome
4.3
10.2
28
72
XCK10
NOMESCO Finland
Photography of fundus of eye
3.7
10.1
34
101
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
41.9
10.1
12
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.5
9.9
81
399
CA1AD
NOMESCO Finland
Orbita CT
+∞
9.4
9
*
CA1BD
NOMESCO Finland
Extensive orbita CT
+∞
9.4
9
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.1
8.7
19
40
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
8.7
111
658
WX002
NOMESCO Finland
Sedation and analgesia
2.7
8.6
53
226
UDM02
NOMESCO Finland
Sinoscopy
9.0
8.5
17
20
J31.0
ICD-10 Finland
Chronic rhinitis
3.4
8.4
32
103
36902
ICD-8 Finland
Other inflammatory diseases of eye, Tenonitis
+∞
8.4
8
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.3
8.2
32
105
XCK00
NOMESCO Finland
Perimetry
4.5
8.1
20
47
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
46.4
7.8
9
*
H02AB07
ATC
prednisone; oral
2.9
7.7
40
155
J01.4
ICD-10 Finland
Acute pansinusitis
25.9
7.6
10
*
F29
ICPC
Eye symptom/complaint other
3.1
7.6
34
121
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
7.5
40
158
ZXE00
NOMESCO Finland
One hour or less
2.1
7.4
102
615
H05.8
ICD-10 Finland
Other disorders of orbit
+∞
7.3
7
*
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
+∞
7.3
7
*
H05.1
ICD-10 Finland
Chronic inflammatory disorders of orbit
+∞
7.3
7
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
7.3
7
*
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
31.0
7.2
9
*
Z3231
NOMESCO Finland
Registered nurse
2.2
7.0
76
415
ZXA05
NOMESCO Finland
Left side
2.3
6.9
63
320
ZXA00
NOMESCO Finland
Right side
2.3
6.9
66
342
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.3
6.9
27
89
H02.4
ICD-10 Finland
Ptosis of eyelid
41.2
6.8
8
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
6.8
96
580
J01DB01
ATC
cefalexin; oral
2.6
6.8
215
1749
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.0
6.7
30
107
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
6.6
32
119
J01FF01
ATC
clindamycin; systemic
2.1
6.6
76
425
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
6.5
54
263
WX720
NOMESCO Finland
Own respiration
4.3
6.5
17
42
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.8
6.4
33
127
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
6.4
116
762
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
6.3
43
191
N02AX02
ATC
tramadol; systemic, rectal
2.0
6.3
106
678
CAE10
NOMESCO Finland
Revision and secondary implant in orbit
+∞
6.3
6
*
Z97.0
ICD-10 Finland
Presence of artificial eye
+∞
6.3
6
*
AA1AD
NOMESCO Finland
CT of head and brain
2.2
6.3
64
340
ZXD05
NOMESCO Finland
Urgent procedure
2.0
6.2
83
488
R01AD09
ATC
mometasone; nasal
1.9
6.1
119
798
R03BA02
ATC
budesonide; inhalant
2.3
6.0
50
243
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
156
1115
2.05
6.93
13.3
9.5
4.26
3.96
e9/l
0.77
143
983
52
252
2.34
6.34
2.1
1.8
—
—
—
0
0
111
736
1.91
5.81
6.0
4.7
35.80
36.35
g/l
0.47
105
701
110
744
1.85
5.29
10.6
5.5
1.21
1.22
mmol/l
0.46
104
688
29
116
2.70
5.26
1.8
1.2
293.97
253.83
u/ml
0.14
29
106
79
484
1.92
5.14
3.3
2.1
121.32
200.89
u/l
2.17
72
457
72
429
1.95
5.08
2.8
2.1
2.99
3.09
mg/l
0.14
67
374
33
146
2.45
4.89
5.2
5.2
1.08
1.95
mmol/l
0.90
26
114
116
812
1.79
4.88
12.9
6.4
1.20
1.22
mmol/l
1.37
105
703
144
1088
1.75
4.55
6.8
3.9
6.67
6.53
mmol/l
0.33
130
989
17
56
3.18
4.33
1.5
1.7
—
—
—
0
0
45
242
2.05
4.18
3.7
2.3
2.44
2.47
g/l
0.12
40
223
93
643
1.71
3.89
4.4
2.9
—
—
—
0
0
47
264
1.96
3.87
3.7
2.3
14.06
13.39
umol/l
0.22
41
245
118
874
1.66
3.78
3.5
2.6
165.22
115.09
ug/l
0.70
111
810
18
67
2.82
3.74
2.4
1.9
1.39
1.35
g/l
0.05
18
62
15
51
3.06
3.64
1.9
1.6
1.31
5.84
iu/l
—
7
17
9
17
5.45
3.54
1.1
1.1
—
—
—
0
0
75
500
1.71
3.53
3.5
2.8
0.32
0.23
e6/l
0.29
57
375
13
37
3.65
3.46
1.3
1.2
62.87
63.63
pmol/l
0.02
13
37
40
222
1.95
3.40
4.2
2.4
20.81
22.53
%
0.34
33
197
33
172
2.06
3.33
1.7
1.6
—
—
—
0
0
15
54
2.89
3.31
1.3
1.8
204.11
150.76
u/ml
—
9
33
93
666
1.63
3.30
3.8
3.2
32.16
30.91
u/l
0.19
85
632
10
24
4.29
3.23
1.5
1.7
—
—
—
0
0
13
44
3.06
3.18
1.7
1.8
—
—
—
0
0
8
16
5.13
3.07
2.3
3.2
3606.38
852.63
u/ml
—
8
16
48
293
1.79
3.04
4.6
3.3
212.65
183.91
ng/l
0.08
31
205
15
57
2.73
3.02
1.7
1.5
—
—
—
0
0
172
1444
1.60
3.01
10.7
7.1
81.36
78.20
u/l
0.38
164
1351
80
564
1.61
2.98
2.5
2.3
72.88
54.68
u/l
0.43
74
524
223
2009
1.96
2.97
21.3
11.5
20.88
22.43
mg/l
0.32
192
1522
13
46
2.93
2.96
1.6
1.8
—
—
—
0
0
103
774
1.56
2.92
15.5
10.8
1.18
1.19
inr
0.04
29
231
10
28
3.67
2.81
1.5
1.6
—
—
—
0
0
9
23
4.02
2.80
1.6
1.6
—
—
—
0
0
80
573
1.58
2.76
3.3
3.2
2.35
2.35
mmol/l
0.10
71
521
7
14
5.11
2.74
1.1
1.1
—
—
—
0
0
31
171
1.93
2.69
1.8
1.5
—
—
—
0
0
12
43
2.88
2.68
1.1
2.2
—
—
—
0
0
98
740
1.53
2.66
2.4
2.3
74.47
74.64
nmol/l
0.02
93
666
122
966
1.51
2.65
7.8
6.2
10.20
11.46
umol/l
1.07
117
917
167
1414
1.54
2.63
6.2
3.7
14.26
10.34
mm/h
2.33
152
1318
31
173
1.90
2.60
1.8
1.8
347.62
371.44
nmol/l
0.29
26
158
90
670
1.53
2.60
2.1
1.7
89.34
97.88
pmol/l
1.13
50
351
13
50
2.69
2.57
1.2
1.2
—
—
—
0
0
16
69
2.41
2.54
2.7
2.2
—
—
—
0
0
29
160
1.92
2.52
2.6
2.4
0.21
0.22
g/l
0.36
29
151
29
160
1.92
2.52
3.2
3.0
—
—
—
0
0
6
12
5.09
2.41
2.3
2.7
—
—
—
0
0
13
52
2.58
2.40
3.8
2.7
—
—
—
0
0
8
22
3.72
2.38
1.4
1.7
—
—
—
0
0
10
34
3.02
2.31
1.6
1.9
—
—
—
0
0
10
34
3.02
2.31
1.6
1.9
—
—
—
0
0
11
40
2.83
2.30
1.3
1.1
—
—
—
0
0
11
40
2.83
2.30
1.3
1.1
—
—
—
0
0
15
66
2.35
2.29
1.3
2.5
—
—
—
0
0
6
13
4.70
2.28
1.0
1.8
—
—
—
0
0
17
80
2.21
2.24
1.9
1.6
—
—
—
0
0
22
115
2.00
2.23
1.7
1.6
—
—
—
0
0
10
35
2.93
2.23
9.4
2.1
—
1.46
—
0
6
5
9
5.64
2.22
1.8
1.4
—
—
—
0
0
56
387
1.57
2.22
1.6
1.4
18.02
20.57
nmol/l
0.87
46
333
18
88
2.13
2.17
3.9
2.4
2015.16
4959.16
u/l
—
9
34
11
42
2.69
2.17
1.4
1.1
—
—
—
0
0
171
1486
1.47
2.13
4.8
3.5
14.70
14.70
pmol/l
0.01
162
1353
25
140
1.87
2.10
1.1
1.2
28.24
142.21
iu/ml
—
7
55
9
32
2.88
2.02
1.2
1.2
—
—
—
0
0
21
113
1.94
1.98
1.6
3.8
4.57
4.78
pmol/l
0.48
21
101
67
494
1.49
1.97
6.3
3.7
17.02
10.93
mg/mmol
0.25
46
316
14
65
2.22
1.92
2.4
1.9
—
—
—
0
0
218
2010
1.63
1.89
22.5
12.6
3.96
3.96
mmol/l
0.02
213
1951
5
12
4.23
1.83
1.2
1.4
—
—
—
0
0
5
12
4.23
1.83
1.6
1.8
—
—
—
0
0
158
1377
1.40
1.77
3.7
3.1
62.43
44.64
u/l
0.64
148
1309
23
133
1.80
1.77
1.9
2.2
—
16.75
—
0
8
6
18
3.39
1.75
2.0
1.9
—
—
—
0
0
6
18
3.39
1.75
2.0
1.9
—
—
—
0
0
6
18
3.39
1.75
2.0
1.9
—
—
—
0
0
11
48
2.35
1.73
1.4
1.2
—
—
—
0
0
45
314
1.53
1.71
1.4
1.3
45.43
31.22
iu/ml
0.38
13
102
21
120
1.82
1.68
1.1
1.2
—
31.96
—
0
5
6
19
3.21
1.67
1.2
1.3
—
—
—
0
0
11
49
2.30
1.66
1.4
1.1
—
1.12
—
0
5
59
440
1.45
1.62
3.3
2.2
—
—
—
0
0
6
20
3.05
1.59
1.2
1.8
—
—
—
0
0
6
20
3.05
1.59
1.2
1.8
—
—
—
0
0
23
138
1.73
1.58
13.3
7.6
9.44
7.98
mmol/l
0.49
23
130
8
33
2.47
1.55
1.6
1.4
—
—
—
0
0
26
163
1.66
1.53
8.8
6.2
0.03
1.06
mmol/l
0.38
19
129
5
15
3.38
1.53
1.2
1.1
—
—
—
0
0
58
436
1.43
1.53
2.8
3.2
1203.89
1127.95
ng/l
0.04
53
367
46
332
1.47
1.49
1.5
1.7
408.00
442.87
pmol/l
0.48
41
287
5
16
3.17
1.44
2.0
1.7
3.20
3.70
mg/l
—
5
16
58
443
1.40
1.40
3.8
2.6
323.53
7844.42
umol/l
2.02
49
393
39
277
1.48
1.37
2.9
2.8
5.23
2.79
e6/l
0.25
20
154
29
193
1.57
1.37
6.3
6.1
104.48
104.21
mmol/l
0.12
29
193
5
17
2.98
1.36
1.2
1.0
—
—
—
0
0
13
68
1.96
1.36
1.4
1.3
—
—
—
0
0
79
640
1.34
1.32
3.8
3.3
28.53
37.33
ng/l
0.43
54
403
6
24
2.54
1.31
1.2
1.1
—
—
—
0
0
106
898
1.31
1.30
3.0
2.5
—
—
—
0
0
14
77
1.87
1.28
1.5
1.4
14.87
24.47
iu/l
—
9
68
40
291
1.45
1.26
2.8
2.6
0.81
1.03
e6/l
0.27
20
167
8
36
2.26
1.25
1.9
1.8
—
—
—
0
0
6
25
2.43
1.25
3.7
3.0
4.73
6.16
u/ml
—
6
25
39
283
1.45
1.24
2.0
1.6
1146.89
1146.91
nmol/l
0.00
34
223
107
914
1.30
1.22
5.4
4.3
0.00
0.00
estimate
-0.00
23
188
8
38
2.14
1.19
1.3
1.4
—
—
—
0
0
195
1808
1.35
1.17
5.7
4.2
1.75
1.83
mu/l
0.54
188
1668
223
2115
1.47
1.15
22.0
13.2
77.38
75.22
umol/l
0.27
223
2115
108
929
1.28
1.15
4.0
3.1
0.00
0.00
estimate
-0.00
23
183
14
81
1.77
1.11
1.3
1.7
—
—
—
0
0
16
97
1.69
1.09
18.4
7.9
25.91
24.81
mmol/l
0.64
16
97
17
105
1.66
1.09
1.5
1.4
—
—
—
0
0
21
139
1.56
1.04
1.7
2.5
72.68
70.62
ml/min/173m2
—
10
58
5
22
2.30
1.04
1.6
1.1
—
—
—
0
0
14
83
1.73
1.03
1.4
1.7
—
—
—
0
0
7
34
2.09
1.03
4.4
3.1
56.43
55.85
%
—
7
34
39
294
1.39
1.02
1.5
1.5
—
—
—
0
0
42
322
1.37
1.00
2.0
2.1
—
—
—
0
0
5
23
2.20
0.98
1.2
1.1
—
—
—
0
0
5
23
2.20
0.98
1.6
1.1
—
—
—
0
0
45
350
1.35
0.98
2.2
2.2
—
—
—
0
0
58
470
1.30
0.96
1.6
1.7
1.28
1.39
mmol/l
0.41
51
405
6
27
2.25
0.94
2.3
1.8
—
—
—
0
0
55
444
1.31
0.93
1.7
1.6
—
—
—
0
0
104
920
1.22
0.81
4.1
3.1
0.00
0.00
estimate
0.50
23
201
39
308
1.31
0.78
1.3
1.3
7.22
12.24
u/ml
0.42
13
128
6
34
1.78
0.77
1.2
1.3
—
—
—
0
0
5
24
2.10
0.75
2.4
1.9
—
—
—
0
0
9
56
1.63
0.73
1.2
1.3
—
—
—
0
0
10
60
1.69
0.73
1.1
1.1
—
—
—
0
0
5
25
2.02
0.73
1.4
1.6
—
—
—
0
0
5
25
2.02
0.73
1.8
1.6
—
—
—
0
0
12
76
1.61
0.73
2.8
4.1
57.74
52.77
%
0.21
12
76
59
497
1.24
0.72
4.6
3.2
0.00
0.00
estimate
-0.00
23
184
17
118
1.47
0.71
5.8
2.2
67.71
67.08
g/l
0.09
17
113
10
61
1.67
0.69
1.1
1.1
—
—
—
0
0
26
197
1.36
0.69
2.3
1.9
—
—
—
0
0
5
29
1.74
0.64
1.4
1.7
—
—
—
0
0
157
1468
1.18
0.62
3.8
3.3
—
—
—
0
0
5
30
1.68
0.61
1.4
1.7
—
—
—
0
0
5
30
1.68
0.61
1.4
1.7
—
—
—
0
0
5
30
1.68
0.61
1.4
1.6
—
—
—
0
0
5
30
1.68
0.61
1.4
1.7
—
—
—
0
0
5
30
1.68
0.61
1.4
1.7
—
—
—
0
0
8
52
1.56
0.60
10.6
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
2.0
—
—
—
0
0
8
55
1.47
0.56
1.1
1.5
—
—
—
0
0
6
37
1.64
0.56
11.0
1.1
0.00
0.00
g/l
—
6
37
6
37
1.64
0.56
11.0
1.1
0.00
0.00
g/l
—
6
37
9
61
1.49
0.54
1.1
1.1
—
—
—
0
0
6
40
1.51
0.52
11.0
1.3
0.00
0.00
g/l
—
6
40
17
223
0.75
0.51
1.8
1.6
—
—
—
0
0
7
46
1.54
0.48
1.6
1.5
—
—
—
0
0
233
2278
1.30
0.47
30.6
17.1
249.88
252.43
e9/l
0.24
228
2228
56
493
1.17
0.45
1.5
1.3
0.85
1.13
u/ml
0.43
15
130
233
2281
1.28
0.43
30.5
17.1
4.44
4.56
e12/l
2.80
227
2224
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
16
123
1.32
0.41
1.1
1.3
—
—
—
0
0
5
34
1.48
0.40
1.2
1.4
—
—
—
0
0
62
557
1.15
0.39
3.6
4.4
6.60
2.58
ug/l
0.36
47
508
0
19
0.00
0.39
0.0
1.6
—
19.03
—
0
19
11
80
1.39
0.39
1.4
2.2
—
—
—
0
0
19
152
1.27
0.38
1.5
1.6
—
—
—
0
0
232
2278
1.23
0.34
30.9
17.0
39.82
40.70
%
1.48
219
2161
6
45
1.34
0.34
3.7
2.6
22.10
24.13
mmol/l
—
6
45
193
1872
1.13
0.33
18.3
10.4
88.07
87.19
ml/min/173m2
0.19
167
1505
19
157
1.23
0.30
2.2
1.8
—
—
—
0
0
77
720
1.10
0.26
4.4
3.1
—
—
—
0
0
183
1783
1.10
0.23
24.6
13.8
14.44
14.52
%
0.07
177
1756
19
162
1.19
0.23
2.0
4.9
2.63
35.48
ug/l
0.69
13
135
190
1855
1.10
0.23
4.9
4.0
5.98
5.84
mmol/l
0.48
175
1717
5
39
1.29
0.23
1.4
1.3
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
4.6
—
119.58
—
0
12
0
13
0.00
0.21
0.0
1.0
—
38.17
—
0
6
0
13
0.00
0.21
0.0
1.0
—
454.29
—
0
7
10
81
1.24
0.19
3.8
2.6
0.61
0.68
%
—
10
81
180
1760
1.08
0.19
6.1
4.9
39.82
39.06
mmol/mol
0.42
172
1651
7
58
1.21
0.18
1.6
1.6
—
—
—
0
0
47
438
1.09
0.17
3.5
4.1
26.27
22.04
%
0.40
14
218
5
68
0.73
0.17
2.0
1.6
—
—
—
0
0
9
78
1.16
0.15
1.3
1.5
—
—
—
0
0
9
78
1.16
0.15
1.3
1.5
—
—
—
0
0
9
78
1.16
0.15
1.3
1.5
—
—
—
0
0
44
411
1.09
0.15
2.0
1.8
2.27
1.15
mg/l
0.45
33
315
24
217
1.12
0.15
4.7
4.4
30.95
30.95
%
0.00
19
151
35
324
1.09
0.15
2.9
2.6
0.48
0.74
ug/l
2.87
23
208
189
1861
1.06
0.13
4.1
3.6
1.34
1.29
mmol/l
0.32
176
1734
10
89
1.13
0.07
1.4
1.6
—
—
—
0
0
191
1920
0.98
0.02
4.5
4.0
1.41
1.46
mmol/l
0.93
178
1794
196
1954
1.01
0.00
5.2
4.4
2.74
2.81
mmol/l
0.47
183
1825
12
121
0.99
0.00
1.0
1.0
—
—
—
0
0
193
1928
1.00
0.00
4.5
4.0
4.61
4.69
mmol/l
0.60
181
1810
21
213
0.98
0.00
10.6
6.3
—
—
—
0
0
7
70
1.00
0.00
1.0
1.1
—
9.68
—
0
11
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
210.29
—
0
7
0
9
0.00
-0.00
0.0
1.2
—
7.77
—
0
9
0
9
0.00
-0.00
0.0
1.3
—
17.00
—
0
9
0
7
0.00
-0.00
0.0
1.3
—
9.43
—
0
7
7
74
0.94
-0.00
2.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
28.32
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_ORBITINFLAMACU and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_ORBITINFLAMACU | 1.673 [1.29, 2.17] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.21 |
During the follow-up period (1.1.1998 — 31.12.2019), 110 out of 905 females with H7_ORBITINFLAMACU died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_ORBITINFLAMACU | 1.943 [1.47, 2.57] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 135 out of 1125 males with H7_ORBITINFLAMACU died.
Mortality risk
Mortality risk for people of age
years, who have H7_ORBITINFLAMACU.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.162% | 0.408% |
| 5 | 0.981% | 2.215% |
| 10 | 2.452% | 5.405% |
| 15 | 4.582% | 9.94% |
| 20 | 7.866% | 16.688% |
Relationships between endpoints
↥Index endpoint: H7_ORBITINFLAMACU – Acute inflammation of orbit
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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