Disorders of orbit

H7_ORBIT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H05, H06*
  • Cause of death: ICD-10 H05, H06*

2 out of 7 registries used, show all original rules.

1671

4. Check minimum number of events

None

1671

5. Include endpoints

1769

6. Filter based on genotype QC (FinnGen only)

1712

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11521 7147 4305
Only index persons 10492 6687 3805
Unadjusted period prevalence (%)
Whole population 0.17 0.20 0.12
Only index persons 0.21 0.25 0.15
Median age at first event (years)
Whole population 48.52 51.10 44.14
Only index persons 48.17 50.74 43.66

-FinnGen-

Key figures

All Female Male
Number of individuals 1712 1205 507
Unadjusted period prevalence (%) 0.37 0.43 0.23
Median age at first event (years) 52.69 52.16 53.97

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1769
Matched controls
17690
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H03AA01
ATC
levothyroxine sodium; systemic
6.1
320.1
969
2926
H03BB01
ATC
carbimazole; oral
42.2
307.7
795
336
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
80.9
307.7
859
204
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
22.0
307.7
267
142
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
38.0
307.7
526
195
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
89.8
307.7
178
22
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
133.4
307.7
169
14
BAA60
NOMESCO Finland
Total thyroidectomy
21.9
307.7
347
195
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
307.7
834
*
H05.2
ICD-10 Finland
Exophthalmic conditions
+∞
307.7
381
*
104
Kela drug reimbursment
Thyroid insufficiency
7.8
263.6
429
701
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
243.5
228
*
H062, E050,
ICD-10 Finland
+∞
230.4
216
*
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
27.9
230.0
158
62
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.8
219.0
1172
5172
H05.0
ICD-10 Finland
Acute inflammation of orbit
2130.9
211.7
201
*
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
23.8
204.6
149
68
H53.2
ICD-10 Finland
Diplopia
11.0
192.5
217
222
H04.10
ICD-10 Finland
Dry eye syndrome
6.8
181.9
322
564
H02.3
ICD-10 Finland
Blepharochalasis
35.8
180.6
114
34
H50.2
ICD-10 Finland
Vertical strabismus
34.4
167.8
107
33
H02.4
ICD-10 Finland
Ptosis of eyelid
32.0
144.2
94
31
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.9
134.2
523
1733
XCK00
NOMESCO Finland
Perimetry
6.3
132.9
245
442
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.6
124.0
342
876
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.1
119.2
857
4092
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
56.4
106.0
60
11
H05.1
ICD-10 Finland
Chronic inflammatory disorders of orbit
+∞
101.0
96
*
H05.9
ICD-10 Finland
Disorder of orbit, unspecified
+∞
97.8
93
*
C07AA05
ATC
propranolol; systemic
3.1
97.8
573
2387
H02AB06
ATC
prednisolone; systemic
2.8
95.1
1043
6019
H05.8
ICD-10 Finland
Other disorders of orbit
+∞
93.6
89
*
H00.03
ICD-10 Finland
Preseptal cellulite in the eyelid
48.7
89.1
52
11
CEC00
NOMESCO Finland
Recession of extraocular muscle
38.2
84.1
52
14
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
32.1
81.6
53
17
CA1AD
NOMESCO Finland
Orbita CT
108.7
67.4
73
7
T85
ICPC
Hyperthyroidism/thyrotoxicosis
13.8
58.9
55
41
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
+∞
58.7
56
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.9
56.1
177
490
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.7
54.9
339
1405
H57.1
ICD-10 Finland
Ocular pain
5.0
54.6
121
254
XCK10
NOMESCO Finland
Photography of fundus of eye
3.3
53.4
227
763
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.6
51.8
128
294
H01.0
ICD-10 Finland
Blepharitis
4.1
51.4
152
401
WF099
NOMESCO Finland
Other radiotherapy
18.2
50.8
41
23
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
8.6
50.4
65
78
ZX120
NOMESCO Finland
Intravenous
3.0
49.2
241
878
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.2
48.9
642
3696
ZXA10
NOMESCO Finland
Bilateral
2.5
48.6
376
1731
XCD10
NOMESCO Finland
Electrophysiological examination of eye
6.1
47.7
85
146
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.3
46.8
96
188
H02AB07
ATC
prednisone; oral
2.6
46.3
315
1362
E03.89
ICD-10 Finland
Other specified hypothyroidism
4.1
46.0
134
349
CAA30
NOMESCO Finland
Biopsy of orbit
125.9
46.0
49
*
H50.6
ICD-10 Finland
Mechanical strabismus
459.2
45.5
45
*
A02BC02
ATC
pantoprazole; systemic
2.2
44.6
1276
9662
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
41.9
516
2866
T86
ICPC
Hypothyroidism/myxoedema
3.7
39.9
131
371
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
39.8
826
5499
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
39.6
726
4634
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.4
39.0
152
482
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
38.8
687
4328
H50.0
ICD-10 Finland
Convergent concomitant strabismus
9.8
38.7
45
47
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
6.0
38.5
69
119
E06.2
ICD-10 Finland
Chronic thyroiditis with transient thyrotoxicosis
385.5
38.2
38
*
CAC44
NOMESCO Finland
Combined decompression of orbit
385.5
38.2
38
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
9.6
38.1
45
48
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
37.4
431
2321
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
84.0
36.9
41
5
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
12.2
36.8
37
31
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.8
36.6
204
793
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
364.5
36.1
36
*
L04AX03
ATC
methotrexate; systemic
2.6
35.2
229
961
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
12.3
35.1
35
29
Z3231
NOMESCO Finland
Registered nurse
2.0
35.1
518
3044
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
14.2
34.8
32
23
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
6.7
34.6
55
84
CAC20
NOMESCO Finland
Lateral decompression of orbit
+∞
34.5
33
*
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
9.7
34.2
40
42
3760A
ICD-9 Finland
Disorders of the orbit, Acute inflammation of orbit
+∞
32.4
31
*
H50.8
ICD-10 Finland
Other specified strabismus
55.4
32.4
38
7
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
115.5
31.8
34
*
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
7.5
31.5
45
61
E03
ICD-10 Finland
Other hypothyroidism
2.9
31.3
157
576
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.7
31.2
186
747
CS494
NOMESCO Finland
Other visual field testing
4.5
30.9
77
178
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
112.1
30.7
33
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.9
29.9
89
235
CAB00
NOMESCO Finland
Anterior orbitotomy with excision of lesion
+∞
29.2
28
*
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
81.5
28.8
32
*
WX002
NOMESCO Finland
Sedation and analgesia
2.0
28.6
359
1974
F29
ICPC
Eye symptom/complaint other
2.5
28.5
195
836
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
+∞
27.1
26
*
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
38.5
27.1
34
9
C07AB07
ATC
bisoprolol; oral
1.7
27.1
812
5829
CA1BD
NOMESCO Finland
Extensive orbita CT
76.4
26.8
30
*
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
264.3
25.8
26
*
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
264.3
25.8
26
*
1XC02, ,
NOMESCO Finland
9.3
25.7
31
34
Z3229
NOMESCO Finland
Other healthcare associate professional
2.6
25.6
163
674
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
+∞
25.1
24
*
S01GX01
ATC
cromoglicic acid; ophthalmic
1.9
24.9
381
2230
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
4.1
24.9
69
173
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
91.4
24.7
27
*
ZXE00
NOMESCO Finland
One hour or less
1.7
24.3
684
4784
H05.5
ICD-10 Finland
Retained (old) foreign body following penetrating wound of orbit
+∞
24.0
23
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.5
23.8
85
254
N05CF01
ATC
zopiclone; oral
1.7
22.8
566
3812
H02AB09
ATC
hydrocortisone; systemic
4.0
22.8
66
171
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.8
22.8
120
451
UDM02
NOMESCO Finland
Sinoscopy
4.2
22.6
61
150
WX402
NOMESCO Finland
General anaesthesia
1.8
22.4
394
2403
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.6
22.3
137
556
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
24.2
22.2
31
13
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
2.6
21.9
130
519
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
7.2
21.7
32
45
WF002
NOMESCO Finland
Radical radiotherapy
3.0
21.5
97
335
L04AA06
ATC
mycophenolic acid; systemic
4.8
20.9
47
100
2AB04, ,
NOMESCO Finland
21.8
20.8
30
14
H50.1
ICD-10 Finland
Divergent concomitant strabismus
8.8
20.7
26
30
A11CC03
ATC
alfacalcidol; systemic
4.1
20.5
56
139
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
48.6
20.2
24
5
H02.8
ICD-10 Finland
Other specified disorders of eyelid
48.6
20.2
24
5
CEW99
NOMESCO Finland
Other operation on extraocular muscle
58.2
19.9
23
*
E05.5
ICD-10 Finland
Thyroid crisis or storm
74.4
19.7
22
*
H10.4
ICD-10 Finland
Chronic conjunctivitis
7.8
19.6
27
35
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.1
19.4
196
986
AA1AD
NOMESCO Finland
CT of head and brain
1.7
19.2
433
2820
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.5
19.2
123
510
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.4
19.1
137
598
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
7.3
19.1
28
39
H02.1
ICD-10 Finland
Ectropion of eyelid
55.6
18.9
22
*
H05.4
ICD-10 Finland
Enophthalmos
+∞
18.8
18
*
ZXA00
NOMESCO Finland
Right side
1.7
18.8
436
2860
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
192.0
18.6
19
*
S01ED01
ATC
timolol; ophthalmic
3.5
18.4
65
193
CBA10
NOMESCO Finland
Biopsy of eyelid
7.2
18.2
27
38
J01DB01
ATC
cefalexin; oral
1.7
18.1
1432
12559
Z2221
NOMESCO Finland
Medical doctor
1.6
17.9
477
3238
XCH00
NOMESCO Finland
Eye pressure measurement
2.8
17.8
89
325
CE2W4
NOMESCO Finland
Eye movement mapping
27.0
17.8
24
9
R51.80
ICD-10 Finland
Headache
1.8
17.8
284
1671
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
17.3
72
237
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
42.4
17.3
21
5
E05.89
ICD-10 Finland
Other thyrotoxicosis
22.1
16.9
24
11
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
64.0
16.8
19
*
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
3.6
16.7
56
161
3763A
ICD-9 Finland
Disorders of the orbit, Other exophthalmic conditions
+∞
16.7
16
*
F01
ICPC
Eye pain
3.3
16.6
63
196
N02AX02
ATC
tramadol; systemic, rectal
1.5
16.6
702
5289
Z3226
NOMESCO Finland
Physiotherapist
1.8
16.6
314
1939
WX140
NOMESCO Finland
Parabulbar anesthesy
2.8
16.6
87
326
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
171.6
16.5
17
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
16.4
1218
10354
ZXA05
NOMESCO Finland
Left side
1.7
16.3
394
2598
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
6.6
16.2
26
40
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
16.0
366
2381
R4110
NOMESCO Finland
Physiotherapy
1.6
15.9
463
3197
CAA00
NOMESCO Finland
Puncture of orbital abscess
+∞
15.6
15
*
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
161.4
15.5
16
*
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.8
15.1
260
1559
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.3
15.1
57
177
S01KA02
ATC
hypromellose; ophthalmic
4.0
15.1
42
106
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
6.3
15.0
25
40
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.4
14.7
53
160
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.1
14.7
146
729
S01ED51
ATC
timolol, combinations; ophthalmic
2.2
14.7
123
574
3762A
ICD-9 Finland
Disorders of the orbit, Endocrine exophthalmos
+∞
14.6
14
*
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
+∞
14.6
14
*
CCA10
NOMESCO Finland
Biopsy of lacrimal gland
+∞
14.6
14
*
H02.2
ICD-10 Finland
Lagophthalmos
80.8
14.6
16
*
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
151.2
14.5
15
*
H02.9
ICD-10 Finland
Disorder of eyelid, unspecified
36.3
14.4
18
5
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.3
14.4
117
539
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.6
14.3
27
49
ZXD20
NOMESCO Finland
Day surgery
1.8
14.2
222
1292
H40.0
ICD-10 Finland
Glaucoma suspect
2.1
14.2
135
663
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
14.2
425
2945
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
14.5
14.1
23
16
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
4.7
14.0
32
69
DPA30
NOMESCO Finland
Sphenotomy
6.3
13.8
23
37
N02BE01
ATC
paracetamol; systemic, rectal
1.7
13.7
1532
13952
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
5.7
13.7
25
44
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
5.2
13.6
28
55
CAE10
NOMESCO Finland
Revision and secondary implant in orbit
+∞
13.6
13
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
11.0
13.5
25
23
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
13.4
217
1277
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
3.8
13.3
40
107
CD2S4
NOMESCO Finland
Photography of eye
10.5
13.2
25
24
A02BC01
ATC
omeprazole; systemic
1.6
13.2
437
3090
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.8
13.2
199
1146
S01EA05
ATC
brimonidine; ophthalmic
3.5
13.1
45
132
2420A
ICD-9 Finland
Thyrotoxicosis with or without goitre, Toxic diffuse goitre
28.6
13.0
17
6
H02AB04
ATC
methylprednisolone; systemic
1.7
12.7
238
1459
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
12.6
458
3298
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
12.6
253
1582
H00.1
ICD-10 Finland
Chalazion
3.2
12.5
49
156
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
12.5
12
*
CBD99
NOMESCO Finland
Other plastic reconstruction of eyelid
+∞
12.5
12
*
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
12.5
12
*
CBB00
NOMESCO Finland
Excision of chalazion
24.5
12.5
17
7
S01XA18
ATC
ciclosporin; ophthalmic
20.2
12.5
18
9
CAW99
NOMESCO Finland
Other operation on orbit
130.9
12.4
13
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
12.4
423
3007
106
Kela drug reimbursment
Hypoparathyroidism
11.7
12.3
22
19
N07BA03
ATC
varenicline; oral
2.4
12.3
88
384
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
12.3
589
4486
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
37.8
12.2
15
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.9
12.2
152
823
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
12.1
210
1260
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
12.0
235
1458
114
Kela drug reimbursment
Glaucoma
2.0
12.0
130
670
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.0
11.9
122
617
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
11.7
81
349
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
5.6
11.7
22
40
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
11.6
196
1167
A02BC05
ATC
esomeprazole; systemic
1.4
11.5
660
5186
36907
ICD-8 Finland
Other inflammatory diseases of eye, Morbi inflammatori orbitae alii
+∞
11.5
11
*
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
+∞
11.5
11
*
CBH30
NOMESCO Finland
Tarsorraphy
+∞
11.5
11
*
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
+∞
11.5
11
*
36900
ICD-8 Finland
Other inflammatory diseases of eye, Abscessus orbitae
+∞
11.5
11
*
N03AX16
ATC
[U] pregabalin
1.5
11.3
371
2606
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
11.3
673
5316
H44.5
ICD-10 Finland
Degenerated conditions of globe
35.3
11.3
14
*
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
5.6
11.2
21
38
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
11.2
584
4505
H03BA02
ATC
propylthiouracil; oral
20.2
11.1
16
8
S01EE01
ATC
latanoprost; ophthalmic
2.2
11.1
94
441
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.8
11.1
164
938
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
11.0
482
3591
J01FF01
ATC
clindamycin; systemic
1.5
11.0
429
3126
S18
ICPC
Laceration/cut
1.4
11.0
696
5555
ZX090
NOMESCO Finland
Other technic of radiotherapy
2.7
10.9
56
209
A97
ICPC
No disease
1.6
10.8
279
1857
XX1XW
NOMESCO Finland
Extensive written report from radiologist
3.2
10.7
42
134
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
10.7
234
1494
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
10.6
128
685
R03BB04
ATC
tiotropium bromide; inhalant
1.8
10.5
151
855
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
10.1
10.5
20
20
H20.1
ICD-10 Finland
Chronic iridocyclitis
4.8
10.5
23
48
CAE00
NOMESCO Finland
Removal of implant from orbit
+∞
10.4
10
*
CS2P4
NOMESCO Finland
Optic nerve head imaging
5.5
10.4
20
37
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
10.4
671
5360
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
10.3
910
7657
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
10.7
10.3
19
18
A04
ICPC
Weakness/tiredness general
1.6
10.1
229
1473
N06AX11
ATC
mirtazapine; oral
1.4
10.1
542
4186
H16.9
ICD-10 Finland
Keratitis, unspecified
3.6
10.1
33
94
R06.0
ICD-10 Finland
Dyspnoea
1.5
10.1
405
2962
S01EC04
ATC
brinzolamide; ophthalmic
2.5
9.9
61
249
H10.5
ICD-10 Finland
Blepharoconjunctivitis
3.4
9.9
35
105
E83.51
ICD-10 Finland
Hypocalcemia
5.2
9.8
20
39
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
5.2
9.8
20
39
H04.0
ICD-10 Finland
Dacryoadenitis
20.1
9.8
14
7
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
9.8
223
1437
R01AD09
ATC
mometasone; nasal
1.4
9.7
749
6140
R03BA02
ATC
budesonide; inhalant
1.5
9.7
291
1999
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
9.7
716
5827
H16.0
ICD-10 Finland
Corneal ulcer
2.2
9.5
79
368
R60.0
ICD-10 Finland
Localized oedema
1.7
9.5
176
1074
CA1CD
NOMESCO Finland
Very extensive orbita CT
+∞
9.4
9
*
CBH25
NOMESCO Finland
Tarsorrhaphy
+∞
9.4
9
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
9.4
76
351
E06.3
ICD-10 Finland
Autoimmune thyroiditis
5.2
9.4
19
37
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.3
9.3
71
319
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
9.2
172
1052
R51.81
ICD-10 Finland
Facial pain NOS
2.8
9.1
44
159
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
5.0
9.1
19
38
ZX050
NOMESCO Finland
Stereotactic radiotherapy
5.0
9.1
19
38
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
9.1
432
3254
H04.2
ICD-10 Finland
Epiphora
11.5
9.1
16
14
A11CC02
ATC
dihydrotachysterol; oral
11.5
9.1
16
14
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
36.9
9.0
11
*
H50.52
ICD-10 Finland
Exophoria
3.7
9.0
28
77
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
9.0
1193
10610
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
8.9
108
579
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
8.9
273
1882
R03AC02
ATC
salbutamol; inhalant
1.4
8.9
904
7704
J01.4
ICD-10 Finland
Acute pansinusitis
4.5
8.8
21
47
R42
ICD-10 Finland
Dizziness and giddiness
1.5
8.8
333
2400
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
8.8
146
865
Z71.8
ICD-10 Finland
Other specified counselling
1.4
8.7
481
3715
J01FA10
ATC
azithromycin; systemic
1.3
8.7
950
8176
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
8.7
564
4477
M25.5
ICD-10 Finland
Pain in joint
1.4
8.6
523
4103
C03CA01
ATC
furosemide; systemic
1.4
8.6
394
2946
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
8.5
334
2423
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.7
8.4
149
898
H04.19
ICD-10 Finland
Other disorders of lacrimal gland
90.5
8.4
9
*
J32.4
ICD-10 Finland
Chronic pansinusitis
3.2
8.4
32
101
S01AD03
ATC
aciclovir; ophthalmic
2.5
8.4
52
214
CEA00
NOMESCO Finland
Biopsy of extraocular muscle
+∞
8.3
8
*
CCD50
NOMESCO Finland
Dacryocystorhinostomy with insertion of tube
+∞
8.3
8
*
36902
ICD-8 Finland
Other inflammatory diseases of eye, Tenonitis
+∞
8.3
8
*
CBF99
NOMESCO Finland
Other operation for ectropion
+∞
8.3
8
*
H05.3
ICD-10 Finland
Deformity of orbit
+∞
8.3
8
*
3761A
ICD-9 Finland
Disorders of the orbit, Chronic inflammatory disorders of orbit
+∞
8.3
8
*
CAE20
NOMESCO Finland
Revision of conjunctival sac with graft
+∞
8.3
8
*
ZXC95
NOMESCO Finland
Use of surgical navigator
3.7
8.3
26
72
J20
ICD-10 Finland
Acute bronchitis
1.7
8.3
159
980
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
9.5
8.3
16
17
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
8.3
112
624
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
8.2
132
774
D06
ICPC
Abdominal pain localized other
1.7
8.1
135
799
H26.4
ICD-10 Finland
After-cataract
1.8
8.1
129
755
J02AC01
ATC
fluconazole; systemic
1.3
8.1
663
5445
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
33.5
8.1
10
*
Z97.0
ICD-10 Finland
Presence of artificial eye
33.5
8.1
10
*
A02BC03
ATC
lansoprazole; oral
1.4
8.1
445
3430
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.2
8.0
64
295
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
3.2
8.0
30
94
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
7.9
300
2160
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
4.5
7.9
19
43
M79.6
ICD-10 Finland
Pain in limb
1.3
7.9
657
5403
S01GX09
ATC
olopatadine; ophthalmic
2.4
7.9
50
208
K02.1
ICD-10 Finland
Caries of dentine
1.3
7.8
950
8246
R53
ICD-10 Finland
Malaise and fatigue
1.4
7.8
361
2695
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
7.8
345
2555
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
8.5
7.8
16
19
WX892
NOMESCO Finland
Monitored bed care
1.8
7.8
111
628
R06AE07
ATC
cetirizine; oral
1.3
7.8
712
5933
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
7.8
831
7083
D07AC01
ATC
betamethasone; topical
1.4
7.7
545
4366
EBA00
NOMESCO Finland
Extraction of tooth
1.4
7.7
552
4431
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
45.2
7.7
9
*
CDC40
NOMESCO Finland
Evisceration of eye with insertion of prosthesis
45.2
7.7
9
*
A01AB09
ATC
miconazole; local oral
1.7
7.7
133
797
A12AA04
ATC
calcium carbonate; oral
3.5
7.7
26
76
J01AA02
ATC
doxycycline; systemic
1.4
7.7
1281
11638
G44.2
ICD-10 Finland
Tension-type headache
1.5
7.7
218
1478
N03AX12
ATC
[U] gabapentin; oral
1.5
7.7
244
1695
S01EE05
ATC
tafluprost; ophthalmic
2.3
7.6
54
236
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
18.4
7.6
11
6
H47.2
ICD-10 Finland
Optic atrophy
8.9
7.5
15
17
R74
ICPC
Upper respiratory infection acute
1.4
7.5
500
3967
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
7.5
288
2078
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
2.6
7.5
42
165
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.4
7.4
300
2184
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
2.8
7.4
36
131
F13
ICPC
Eye sensation abnormal
2.5
7.4
46
190
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
7.3
257
1820
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
7.3
356
2682
CDC10
NOMESCO Finland
Enucleation of eye with insertion of prosthesis
+∞
7.3
7
*
CBN20
NOMESCO Finland
Shortening of eyelid retractors
+∞
7.3
7
*
CA1DM
NOMESCO Finland
Eye and orbita very extensive MRI examination with 3 Tesla magnet
+∞
7.3
7
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.9
7.3
95
524
P01AB01
ATC
metronidazole; oral, rectal
1.3
7.3
641
5301
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
15.8
7.2
11
7
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.0
7.2
30
100
E0000UV, ,
ATC
1.3
7.2
635
5248
S01AA01
ATC
chloramphenicol; ophthalmic
2.0
7.2
75
383
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
7.2
156
993
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.7
7.2
38
145
R5599
NOMESCO Finland
Other rehabilitation service
2.4
7.1
47
199
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
7.1
273
1967
SPAT1009
SPAT
Measurement of intraocular pressure
3.4
7.1
25
75
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.4
7.1
352
2659
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
12.1
7.1
12
10
WW200
NOMESCO Finland
Immunization
2.5
7.0
42
170
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
3.9
7.0
20
52
N05BA04
ATC
oxazepam; oral
1.4
7.0
395
3050
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
7.0
409
3177
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.9
751
6377
J01MA14
ATC
moxifloxacin; systemic
1.7
6.9
129
789
F03
ICPC
Eye discharge
1.8
6.9
98
554
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.9
6.9
86
467
JN4BD
NOMESCO Finland
Extensive body CT
1.6
6.9
144
908
R01AD08
ATC
fluticasone; nasal
1.4
6.9
446
3518
L15
ICPC
Knee symptom/complaint
1.4
6.8
365
2789
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
6.8
266
1923
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.4
6.8
43
179
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
6.8
168
1104
CAB10
NOMESCO Finland
Lateral orbitotomy with excision of lesion
40.2
6.8
8
*
XCW10
NOMESCO Finland
Assessment of vision
3.7
6.8
21
58
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
6.7
103
597
H15.1
ICD-10 Finland
Episcleritis
3.3
6.7
24
73
H10
ICD-10 Finland
Conjunctivitis
1.7
6.7
107
628
M03BX02
ATC
tizanidine; oral
1.3
6.7
1012
8972
J01DA01
ATC
[U] cefalexin
1.3
6.7
991
8762
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.6
405
3161
ZXD05
NOMESCO Finland
Urgent procedure
1.4
6.6
443
3508
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.3
6.6
49
219
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
7.8
6.6
14
18
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
7.8
6.6
14
18
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
5.5
6.6
18
33
H25.1
ICD-10 Finland
Senile nuclear cataract
1.4
6.6
333
2520
H52.2
ICD-10 Finland
Astigmatism
2.7
6.6
34
128
R4120
NOMESCO Finland
Occupational therapy
1.8
6.6
98
563
XCH05
NOMESCO Finland
Eye pressure longterm registration
4.2
6.6
17
41
M54.5
ICD-10 Finland
Low back pain
1.3
6.5
555
4549
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
6.5
326
2462
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.5
609
5061
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
6.5
446
3547
H26.3
ICD-10 Finland
Drug-induced cataract
5.7
6.5
17
30
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
3.9
6.4
18
46
H53.8
ICD-10 Finland
Other visual disturbances
3.2
6.4
24
75
E50.0
ICD-10 Finland
Vitamin A deficiency with conjunctival xerosis
70.1
6.4
7
*
3112
FHL
Orbitotomy (includes biopsy and removal of local tumor or foreign object)
70.1
6.4
7
*
R03BA01
ATC
beclometasone; inhalant
1.5
6.4
211
1477
L28
ICPC
Limited function/disability (L)
1.5
6.4
236
1689
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
3.1
6.4
26
86
A07AA02
ATC
nystatin; oral
1.8
6.3
85
473
R50.9
ICD-10 Finland
Fever, unspecified
1.5
6.3
211
1478
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.3
377
2929
N05BA01
ATC
diazepam; systemic, rectal
1.5
6.3
191
1311
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.2
6.3
48
217
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
6.3
240
1726
M05BA04
ATC
alendronic acid; oral
1.7
6.3
125
778
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
11.1
6.3
11
10
H54.4
ICD-10 Finland
Blindness, monocular
11.1
6.3
11
10
H060, E050,
ICD-10 Finland
+∞
6.3
6
*
CBG10
NOMESCO Finland
Cryotherapy for trichiasis
+∞
6.3
6
*
CAB50
NOMESCO Finland
Orbitotomy with removal of foreign body
+∞
6.3
6
*
C69.60
ICD-10 Finland
Malignant tumor in orbit without histology
+∞
6.3
6
*
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
+∞
6.3
6
*
CBN30
NOMESCO Finland
Shortening of canthal ligament
+∞
6.3
6
*
G73.0*E05.9
ICD-10 Finland
Myasthenic syndromes in thyrotoxicosis [hyperthyroidism]
+∞
6.3
6
*
CDC00
NOMESCO Finland
Enucleation of eye
26.8
6.2
8
*
CFD10
NOMESCO Finland
Repair of conjunctiva
26.8
6.2
8
*
SPF40
NOMESCO Finland
Removal and reattachment of crown or small bridge
2.8
6.2
30
109
S06.0
ICD-10 Finland
Concussion
1.6
6.2
154
1013
K90.0
ICD-10 Finland
Coeliac disease
2.2
6.2
48
219
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.2
280
2080
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
3.4
6.1
21
62
H25.8
ICD-10 Finland
Other senile cataract
1.6
6.1
130
823
R05
ICPC
Cough
1.4
6.1
359
2784
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
12.6
6.1
10
8
H57.8
ICD-10 Finland
Other specified disorders of eye and adnexa
12.6
6.1
10
8
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
8.6
6.1
12
14
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
6.1
128
810
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.8
6.0
81
451
R07.0
ICD-10 Finland
Pain in throat
1.7
6.0
98
578
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
6.0
261
1923
SXC03
NOMESCO Finland
Other oral or dental procedure
3.4
6.0
21
63

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
569
944
8.41
307.65
7.1
3.3
4.58
4.51
pmol/l
0.44
540
840
590
364
23.82
307.65
4.5
1.8
5.90
4.67
iu/l
1.11
378
133
1521
11593
3.23
67.58
11.0
4.1
15.40
14.72
pmol/l
20.73
1439
10621
1188
8345
2.29
56.93
10.8
8.8
4.09
4.02
e9/l
0.47
1045
7315
286
1064
3.01
56.71
1.4
1.2
203.12
150.82
iu/ml
1.26
124
407
1026
6897
2.16
53.40
7.9
6.5
1.21
1.22
mmol/l
1.38
888
5873
942
6242
2.09
49.50
6.7
5.8
1.21
1.22
mmol/l
0.93
892
5694
982
6710
2.04
46.25
7.4
6.1
—
—
—
0
0
1022
7139
2.02
44.60
7.0
5.6
0.59
0.56
e9/l
2.29
887
6195
1022
7152
2.02
44.21
7.0
5.6
0.04
0.04
e9/l
0.73
886
6203
674
4078
2.05
43.91
4.9
3.9
7.39
7.40
ph
1.47
126
774
1047
7403
2.02
43.82
7.2
5.8
0.20
0.19
e9/l
1.54
919
6519
1042
7360
2.01
43.68
7.0
5.6
1.91
1.94
e9/l
0.28
929
6537
992
6949
1.97
41.86
7.1
5.7
27.98
28.50
%
0.82
937
6536
967
6745
1.96
40.99
7.4
5.9
8.68
8.43
%
1.57
915
6327
98
219
4.68
40.98
2.1
1.7
0.77
0.81
g/l
0.12
73
170
940
6495
1.95
40.97
7.1
5.7
0.69
0.68
%
0.33
886
6062
962
6702
1.95
40.88
7.1
5.7
3.01
2.82
%
1.43
906
6270
976
6850
1.95
40.38
6.9
5.5
56.88
56.79
%
0.09
922
6434
1599
13678
2.76
36.39
11.9
4.8
1.74
2.11
mu/l
1.64
1517
12607
1371
11032
2.08
35.69
9.3
7.3
77.88
78.00
u/l
0.03
1318
10370
719
4796
1.84
32.53
3.6
3.4
2.34
2.36
mmol/l
1.99
644
4241
580
3657
1.87
31.10
8.1
6.4
—
—
—
0
0
364
1967
2.07
30.59
1.4
1.3
372.20
501.64
titre
1.51
82
403
230
1044
2.38
29.68
3.5
3.8
64.23
82.95
ng/l
3.63
203
917
272
1327
2.24
29.64
2.5
2.0
354.69
372.05
nmol/l
0.81
250
1225
1313
10777
1.85
27.28
5.1
3.9
12.93
11.83
mm/h
1.88
1235
9980
834
6025
1.73
27.22
2.6
2.2
76.22
77.27
nmol/l
0.50
761
5422
60
126
4.89
27.01
1.6
1.4
0.33
0.37
g/l
0.38
44
89
60
126
4.89
27.01
1.6
1.4
6.30
6.80
g/l
0.44
43
89
60
126
4.89
27.01
1.6
1.4
3.02
2.92
g/l
0.14
43
87
61
130
4.82
26.99
1.6
1.4
—
—
—
0
0
1056
8167
1.73
26.65
5.0
4.6
6.51
6.64
mmol/l
1.18
992
7599
143
577
2.61
23.60
1.9
1.4
14.55
8.77
u/ml
—
6
11
807
5944
1.66
23.25
4.9
4.7
35.57
35.84
g/l
0.72
759
5550
105
369
2.96
22.53
1.8
2.2
11.22
12.15
mg/l
0.50
100
341
851
6430
1.62
21.60
10.9
8.8
0.00
0.00
e9/l
0.09
691
5250
108
397
2.83
21.35
1.3
1.2
94.14
33.65
u/ml
—
7
21
1623
14681
2.28
20.65
17.3
12.8
21.85
22.51
mg/l
0.34
1339
11468
278
1558
1.93
20.40
2.0
1.6
—
—
—
0
0
208
1078
2.05
19.02
3.4
2.6
10.07
10.48
g/l
0.60
192
985
87
303
2.97
18.97
1.2
1.2
61.01
45.76
u/ml
—
8
30
431
2832
1.69
18.39
1.6
1.4
2.34
2.35
g/l
0.02
256
1771
735
5531
1.56
17.86
2.1
1.9
96.66
96.03
pmol/l
0.12
365
2831
535
3743
1.62
17.73
3.2
2.9
0.38
0.44
e6/l
0.18
387
2792
922
7348
1.53
16.94
6.5
6.1
10.73
11.12
umol/l
0.55
882
6987
37
77
4.89
16.87
1.1
1.1
1.33
1.70
nmol/l
—
9
14
519
3674
1.58
16.09
3.2
2.9
—
—
—
0
0
272
1625
1.80
16.08
1.5
1.6
—
—
—
0
0
1634
15066
2.11
15.78
19.4
14.6
3.93
3.96
mmol/l
3.79
1606
14637
1125
9436
1.53
15.73
4.8
4.2
32.71
2149.70
e6/l
—
7
131
1629
15018
2.07
15.50
19.1
14.5
139.69
139.69
mmol/l
0.03
1605
14618
304
1898
1.73
15.38
2.2
2.0
—
—
—
0
0
645
4842
1.52
15.17
4.1
3.5
82.29
107.31
e6/l
0.52
431
3331
90
362
2.57
14.95
1.3
1.2
12.88
2.35
u/ml
—
5
33
91
369
2.55
14.87
1.3
1.2
16.90
11.36
u/ml
—
8
58
52
155
3.43
14.71
3.2
4.5
39.49
78.72
u/ml
0.74
13
44
374
2505
1.63
14.38
3.1
2.9
2.44
2.45
mmol/l
0.29
324
2201
490
3512
1.55
14.05
4.6
3.8
92.20
93.14
%
0.33
481
3412
750
5903
1.47
13.55
2.2
2.0
—
—
—
0
0
330
2172
1.64
13.54
3.7
3.5
0.81
0.82
mmol/l
0.32
309
2046
1476
13330
1.65
13.43
6.1
5.3
39.44
39.46
mmol/mol
0.03
1388
12368
333
2214
1.62
13.08
1.5
1.6
—
—
—
0
0
551
4103
1.50
13.02
3.4
3.0
44.22
53.73
e6/l
0.28
400
3096
158
851
1.94
12.86
1.9
1.7
1.31
1.40
g/l
0.17
145
783
1151
9889
1.47
12.84
5.0
4.1
—
—
—
0
0
382
2653
1.56
12.40
1.8
1.9
—
—
—
0
0
551
4155
1.47
12.04
2.4
2.0
159.83
220.20
u/l
1.24
502
3916
470
3437
1.50
11.96
2.5
2.1
2.77
2.96
mg/l
1.28
424
2914
762
6118
1.43
11.89
14.3
13.0
1.23
1.21
inr
0.12
221
1774
184
1070
1.80
11.77
1.3
1.4
—
—
—
0
0
381
2678
1.54
11.64
3.1
2.7
537.10
536.50
mosm/kgh2o
0.02
318
2300
366
2552
1.55
11.59
4.1
3.5
329.54
455.45
ng/l
0.39
282
1865
1135
9823
1.43
11.45
3.5
3.0
44.60
46.15
u/l
0.24
1076
9185
159
896
1.85
11.26
2.9
2.4
—
—
—
0
0
46
151
3.10
11.20
1.9
1.5
—
—
—
0
0
393
2806
1.51
11.10
2.7
2.4
7.04
6.80
e6/l
0.10
342
2507
1162
10136
1.43
10.96
3.9
3.5
—
—
—
0
0
50
175
2.91
10.90
1.1
1.2
—
53.53
—
0
10
182
1079
1.77
10.90
2.9
2.7
66.65
66.79
g/l
0.09
169
985
1415
12827
1.52
10.81
22.3
15.4
14.56
14.82
%
1.17
1397
12587
617
4834
1.42
10.73
3.4
3.2
29.53
33.02
u/l
1.57
579
4597
472
3520
1.46
10.70
4.7
4.1
—
—
—
0
0
784
6408
1.40
10.68
3.3
2.7
131.06
114.68
ug/l
0.62
735
5946
192
1169
1.72
10.46
1.2
1.2
—
—
—
0
0
62
251
2.52
10.24
2.1
3.0
—
—
—
0
0
1534
14198
1.61
10.23
5.0
4.3
5.89
5.88
mmol/l
0.15
1432
12973
264
1756
1.59
10.18
5.6
5.6
1.04
1.04
mmol/l
0.01
242
1616
563
4379
1.42
10.06
2.7
2.5
57.48
76.75
u/l
0.53
528
4057
88
419
2.16
10.04
1.7
1.5
0.24
0.23
g/l
0.18
80
397
106
544
2.01
9.92
1.3
1.2
0.24
1.43
u/ml
—
10
44
581
4554
1.41
9.90
2.6
2.3
—
—
—
0
0
441
3306
1.44
9.57
1.4
1.2
1.30
1.66
u/ml
0.45
116
884
65
278
2.39
9.56
1.9
1.9
5.00
5.24
mmol/24h
0.26
55
246
842
7050
1.37
9.53
5.2
4.7
0.00
0.00
estimate
0.50
177
1312
89
436
2.10
9.46
1.6
1.5
1.19
1.19
g/l
0.03
81
413
360
2605
1.48
9.36
1.3
1.3
23.86
34.13
iu/ml
1.36
100
864
303
2120
1.52
9.28
3.0
2.7
3.57
3.20
e6/l
0.16
150
1120
320
2267
1.50
9.23
2.8
2.6
1.40
1.14
e6/l
0.33
166
1256
847
7127
1.36
9.15
3.8
3.5
0.02
0.01
estimate
0.25
170
1274
1654
15698
1.83
8.98
14.0
9.8
25.41
25.90
u/l
0.61
1619
15166
81
400
2.07
8.45
3.7
2.4
38.16
37.91
g/l
0.17
75
358
157
960
1.70
8.42
1.6
1.3
311.26
202.87
u/ml
0.73
152
877
81
401
2.07
8.40
2.5
3.2
—
—
—
0
0
411
3106
1.42
8.39
1.5
1.5
20.00
21.02
nmol/l
0.81
351
2639
449
3458
1.40
8.20
2.6
2.2
—
—
—
0
0
91
475
1.97
8.16
3.5
2.5
10.22
9.99
g/l
0.16
85
432
831
7058
1.33
8.06
3.8
3.5
0.00
0.00
estimate
0.75
183
1391
339
2491
1.45
8.04
1.3
1.3
9.88
11.76
u/ml
0.20
108
996
143
873
1.69
7.72
2.0
1.7
—
—
—
0
0
271
1930
1.48
7.53
2.5
2.4
2.39
2.37
g/l
0.31
249
1792
211
1430
1.54
7.43
2.7
2.6
1.64
1.79
%
2.03
198
1275
237
1655
1.50
7.25
1.8
1.4
—
—
—
0
0
418
3244
1.38
7.17
3.6
3.5
—
—
—
0
0
155
991
1.62
7.01
3.0
2.8
6.21
5.47
e9/l
0.14
132
829
277
2008
1.45
7.00
2.6
2.2
29.96
29.52
s
0.44
261
1944
210
1442
1.52
6.95
1.5
1.4
—
—
—
0
0
96
546
1.80
6.66
1.8
1.9
1.53
1.53
g/l
0.01
81
476
228
1610
1.48
6.59
2.4
2.7
5.74
8.06
umol/l
2.97
195
1391
50
226
2.25
6.58
1.4
1.3
—
—
—
0
0
162
1064
1.58
6.55
2.8
2.6
70.28
70.13
e9/l
0.02
114
806
142
905
1.62
6.51
1.3
1.3
37.54
52.67
au/ml
—
5
60
186
1265
1.53
6.44
1.5
1.4
—
—
—
0
0
672
5664
1.30
6.43
3.6
3.2
5.86
5.86
ph
0.00
47
452
210
1468
1.49
6.38
6.9
7.9
5.18
5.09
kpa
0.71
197
1405
210
1468
1.49
6.38
6.9
7.9
12.42
12.64
kpa
0.24
196
1405
209
1461
1.49
6.35
6.9
8.0
1.38
1.13
mmol/l
0.41
163
1167
111
669
1.70
6.32
7.6
9.8
24.96
24.42
mmol/l
1.07
105
653
531
4348
1.32
6.25
3.4
3.0
—
—
—
0
0
26
87
3.02
6.24
1.8
1.4
5.28
6.89
u/l
0.96
20
76
246
1782
1.44
6.22
2.7
2.5
21.76
23.30
%
0.96
208
1528
316
2401
1.38
6.08
1.8
1.7
1094.63
1212.00
nmol/l
1.68
238
1805
525
4308
1.31
6.05
3.2
3.2
7.39
7.34
mmol/l
0.08
442
3660
36
146
2.50
6.04
1.2
1.2
—
—
—
0
0
38
160
2.41
5.90
2.4
2.8
—
—
—
0
0
607
5092
1.29
5.90
3.3
3.4
31.75
41.43
ng/l
0.54
366
3301
282
2116
1.40
5.84
2.6
2.4
13.17
13.57
umol/l
0.39
262
1976
787
6831
1.27
5.80
2.7
2.5
—
—
—
0
0
186
1294
1.49
5.78
2.4
2.3
30.50
39.99
u/l
1.58
155
1103
57
289
2.00
5.64
1.3
1.7
—
—
—
0
0
149
999
1.54
5.52
2.4
2.4
14.22
23.25
au/ml
—
5
90
71
391
1.85
5.52
4.3
3.5
37.87
73.10
mg/l
1.13
52
322
41
185
2.25
5.47
2.0
2.9
—
—
—
0
0
241
1790
1.40
5.28
2.1
2.2
174.00
116.79
ug/g
0.71
195
1435
1605
15376
1.47
5.26
16.9
12.1
—
—
—
0
0
70
392
1.82
5.18
4.3
3.5
54.32
43.38
mg/l
0.19
52
324
149
1015
1.51
5.14
2.4
3.0
181.11
165.90
ng/l
0.19
129
928
244
1826
1.39
5.11
1.2
1.3
—
—
—
0
0
169
1185
1.47
5.07
3.4
3.6
2.55
1.92
mmol/l
1.65
127
990
258
1955
1.37
5.01
1.2
1.2
—
—
—
0
0
26
99
2.65
4.99
5.3
6.3
—
—
—
0
0
29
117
2.50
4.97
1.6
1.3
2.11
1.09
u/ml
0.31
20
64
52
268
1.97
4.95
1.3
1.2
—
—
—
0
0
1695
16465
1.70
4.88
28.0
18.9
259.08
256.32
e9/l
0.97
1657
16040
54
285
1.92
4.81
1.5
1.5
—
—
—
0
0
1695
16472
1.69
4.77
27.8
18.9
90.97
90.83
fl
0.63
1681
16240
1695
16474
1.69
4.74
27.8
18.8
30.23
30.22
pg
0.03
1681
16239
466
3868
1.28
4.74
1.6
1.6
1.36
1.38
mmol/l
0.30
393
3257
1695
16475
1.69
4.73
27.9
18.9
4.48
4.48
e12/l
0.03
1653
16003
1695
16477
1.69
4.70
27.9
18.9
6.80
6.67
e9/l
1.16
1654
16001
32
139
2.33
4.69
1.5
1.7
—
—
—
0
0
154
1078
1.47
4.67
7.5
8.3
—
—
—
0
0
27
109
2.50
4.63
1.1
1.1
—
—
—
0
0
1695
16482
1.68
4.62
28.1
19.0
134.51
134.83
g/l
0.43
1682
16246
1692
16447
1.66
4.60
28.0
19.0
40.18
40.31
%
0.16
1611
15442
152
1069
1.46
4.51
3.9
4.1
0.96
0.69
%
0.10
45
273
166
1189
1.44
4.47
3.4
3.6
5.74
5.84
kpa
0.67
152
1149
439
3649
1.27
4.37
2.7
2.9
1089.29
1135.49
ng/l
0.10
368
3048
63
361
1.77
4.37
1.3
1.4
13.59
10.84
u/l
0.60
46
290
110
730
1.54
4.32
1.4
1.4
27.39
30.90
iu/l
0.56
87
625
211
1591
1.37
4.23
1.3
1.3
—
—
—
0
0
84
526
1.63
4.22
1.1
1.1
—
—
—
0
0
14
41
3.43
4.18
2.6
2.4
0.96
1.13
ug/l
0.17
14
36
26
109
2.41
4.15
1.3
1.1
62.86
147.14
titre
—
7
21
472
3979
1.25
4.14
3.3
3.2
447.66
374.26
mg/l
0.12
298
2474
158
1139
1.43
4.12
4.1
4.0
0.06
0.12
%
1.04
52
335
157
1136
1.42
4.02
3.6
3.6
1.23
1.23
mmol/l
0.24
143
983
164
1196
1.41
4.01
4.0
4.0
1.00
1.08
%
0.17
58
392
156
1133
1.41
3.91
6.3
7.0
1.23
1.37
mmol/l
1.43
147
1104
138
982
1.44
3.88
1.6
1.4
—
—
—
0
0
32
153
2.11
3.79
1.4
1.2
—
—
—
0
0
26
114
2.30
3.78
1.2
1.1
—
—
—
0
0
14
44
3.20
3.78
1.0
1.4
—
—
—
0
0
149
1091
1.40
3.58
7.4
7.9
8.85
9.19
mmol/l
0.27
139
1038
172
1291
1.37
3.57
7.6
8.5
95.95
95.84
%
0.09
163
1245
50
286
1.77
3.54
3.4
3.5
56.96
57.87
%
0.18
50
286
148
1085
1.40
3.54
4.2
3.8
0.80
0.68
%
0.16
49
340
63
389
1.64
3.40
1.2
1.1
—
—
—
0
0
425
3611
1.23
3.40
2.7
2.5
3296.38
5573.86
umol/l
0.64
380
3188
103
713
1.47
3.37
2.5
2.3
—
—
—
0
0
13
42
3.11
3.37
1.0
1.0
—
—
—
0
0
163
1225
1.36
3.36
5.0
3.7
—
—
—
0
0
43
239
1.82
3.36
1.0
1.1
0.96
2.20
u/ml
0.95
26
126
113
797
1.45
3.36
1.3
1.2
—
—
—
0
0
50
291
1.74
3.36
4.0
3.7
—
—
—
0
0
385
3242
1.24
3.34
1.9
1.8
1.15
1.14
mg/l
0.02
287
2438
486
4201
1.22
3.27
3.9
3.8
9.83
7.96
mg/mmol
0.30
295
2590
51
309
1.67
3.00
1.5
1.6
1257.30
1698.33
e6/l
0.13
40
250
51
309
1.67
3.00
1.5
1.5
49.21
14.50
e6/l
0.90
39
236
64
412
1.57
2.96
5.8
8.3
1.37
1.27
mmol/l
0.37
57
355
29
148
1.98
2.95
1.4
1.9
—
—
—
0
0
97
684
1.44
2.92
9.6
11.8
—
—
—
0
0
8
17
4.72
2.92
1.5
3.8
—
—
—
0
0
49
298
1.66
2.85
1.3
1.4
—
—
—
0
0
62
401
1.57
2.83
1.4
1.4
255.97
300.62
ug/g
0.91
36
223
158
1216
1.33
2.82
8.1
8.9
122.06
121.07
g/l
0.25
152
1182
22
104
2.13
2.75
1.2
1.1
320.75
251.52
mg/l
0.52
16
86
1330
12676
1.20
2.75
24.3
16.5
331.70
332.11
g/l
0.95
1318
12579
78
535
1.48
2.73
1.7
1.6
—
—
—
0
0
13
48
2.72
2.72
1.0
1.1
—
—
—
0
0
39
226
1.74
2.71
1.5
2.3
—
—
—
0
0
205
1646
1.28
2.68
1.7
1.7
—
—
—
0
0
68
455
1.51
2.68
1.3
1.3
—
—
—
0
0
44
265
1.68
2.67
1.8
3.2
31.74
34.46
umol/l
0.45
39
239
12
43
2.80
2.64
1.2
1.1
—
—
—
0
0
1529
14790
1.25
2.64
5.1
4.7
2.83
2.83
mmol/l
0.03
1421
13675
45
274
1.66
2.63
1.4
1.4
223.55
110.78
u/ml
0.48
11
47
37
214
1.74
2.60
1.7
1.8
—
—
—
0
0
10
30
3.35
2.60
1.0
1.1
—
—
—
0
0
10
30
3.35
2.60
1.0
1.1
—
—
—
0
0
10
30
3.35
2.60
1.0
1.1
—
—
—
0
0
24
121
2.00
2.56
2.1
1.9
38.71
40.52
%
0.24
24
121
30
167
1.81
2.41
1.2
1.3
—
—
—
0
0
32
183
1.76
2.36
1.0
1.1
1.91
4.28
u/ml
0.83
16
74
61
411
1.50
2.36
1.1
1.1
2.28
6.33
u/ml
—
6
51
22
111
1.99
2.36
1.3
1.2
39.88
39.47
mg/l
0.02
14
90
42
260
1.63
2.34
2.2
3.1
—
—
—
0
0
19
91
2.10
2.33
3.2
2.8
68.26
96.30
nmol/l
1.22
19
91
73
512
1.44
2.32
1.7
1.6
296.94
292.15
mu/l
0.08
68
458
17
78
2.19
2.31
1.6
1.5
1.25
1.33
nmol/l
0.10
12
62
100
743
1.37
2.29
2.6
2.2
10.83
12.35
nmol/l
0.95
90
665
164
1308
1.28
2.29
2.5
2.2
0.21
0.21
g/l
0.12
150
1227
11
40
2.76
2.27
1.1
1.6
127.82
82.55
nmol/24h
0.26
11
40
42
263
1.61
2.24
1.0
1.1
1.61
5.39
u/ml
3.51
27
138
111
842
1.34
2.23
5.2
5.7
—
—
—
0
0
29
164
1.78
2.23
2.0
2.2
4.27
4.99
umol/l
0.32
19
117
62
425
1.48
2.22
1.1
1.2
—
—
—
0
0
10
35
2.87
2.21
1.0
1.2
—
—
—
0
0
174
1410
1.26
2.15
1.6
1.7
—
—
—
0
0
451
4007
1.17
2.14
3.7
3.6
—
—
—
0
0
76
547
1.41
2.12
2.6
2.1
21.22
21.11
s
0.08
69
482
14
62
2.27
2.08
1.3
1.8
—
—
—
0
0
5
10
5.01
2.07
2.0
1.4
—
—
—
0
0
18
89
2.03
2.06
2.1
1.5
—
—
—
0
0
6
15
4.01
2.04
1.2
1.2
—
—
—
0
0
69
493
1.42
2.02
1.2
1.3
181.37
221.93
miu/ml
0.40
30
237
170
1388
1.25
1.98
6.3
4.0
—
—
—
0
0
436
3894
1.16
1.92
3.6
3.1
—
—
—
0
0
123
970
1.29
1.91
3.0
3.0
4.80
4.55
kpa
0.94
115
936
33
205
1.62
1.86
1.1
1.0
2.58
2.41
u/ml
0.04
17
95
34
213
1.61
1.86
1.1
1.0
1.88
2.68
u/ml
0.42
12
90
13
59
2.21
1.84
1.6
3.2
—
—
—
0
0
39
254
1.55
1.82
1.0
1.1
0.68
1.97
u/ml
1.05
24
112
135
1086
1.26
1.80
2.2
2.3
5.98
7.37
ug/l
0.71
111
971
43
287
1.51
1.80
7.1
10.3
11.16
11.39
mmol/l
0.18
37
253
17
87
1.96
1.80
3.4
2.3
48.89
41.70
%
—
9
49
194
1626
1.22
1.79
6.7
6.7
104.08
104.28
mmol/l
0.24
194
1626
1497
14563
1.18
1.78
4.5
4.3
4.75
4.76
mmol/l
0.24
1398
13558
421
3770
1.15
1.78
4.3
3.8
0.00
0.00
estimate
1.08
177
1287
43
288
1.51
1.78
7.1
10.3
105.70
105.17
mmol/l
0.36
37
254
14
67
2.10
1.76
1.4
1.5
—
—
—
0
0
455
4103
1.15
1.74
1.5
1.5
—
—
—
0
0
12
54
2.23
1.74
45.3
30.5
5.89
7.20
ug/l
1.59
12
49
71
526
1.36
1.72
1.6
1.9
—
—
—
0
0
62
449
1.39
1.72
2.6
2.2
144.70
378.06
ug/l
1.49
56
419
19
103
1.85
1.72
2.7
2.1
—
—
—
0
0
67
494
1.37
1.68
1.6
2.0
—
—
—
0
0
53
376
1.42
1.66
1.1
1.1
—
—
—
0
0
8
31
2.59
1.66
1.3
1.1
—
—
—
0
0
71
530
1.35
1.65
1.6
2.0
—
—
—
0
0
7
25
2.81
1.65
1.3
1.0
10.13
6.05
mg/g
—
7
25
11
49
2.25
1.63
2.4
2.7
—
—
—
0
0
43
295
1.47
1.61
1.0
1.1
0.89
2.15
u/ml
1.05
25
159
13
63
2.07
1.60
1.2
1.1
1695.23
1721.24
miu/ml
0.02
13
63
53
380
1.41
1.58
1.2
1.2
—
81.25
—
0
32
7
26
2.70
1.58
3.6
1.3
—
—
—
0
0
57
415
1.39
1.56
1.7
1.8
—
—
—
0
0
71
536
1.34
1.55
1.6
2.0
—
—
—
0
0
27
168
1.62
1.55
1.1
1.0
0.07
0.46
u/ml
1.45
11
60
179
1512
1.20
1.55
1.3
1.4
—
—
—
0
0
14
71
1.98
1.54
1.4
1.2
—
—
—
0
0
71
537
1.34
1.54
1.6
2.0
—
—
—
0
0
5
15
3.34
1.52
1.2
1.3
32.44
89.95
ng/l
—
5
15
7
27
2.60
1.51
2.1
2.0
—
—
—
0
0
27
170
1.60
1.49
1.1
1.2
—
—
—
0
0
103
824
1.27
1.48
5.5
3.6
7.42
7.41
ph
0.18
19
105
34
227
1.51
1.47
2.1
1.4
—
—
—
0
0
1484
14478
1.16
1.45
4.4
4.2
1.47
1.50
mmol/l
2.43
1370
13398
41
286
1.44
1.44
1.3
1.3
241.75
249.30
u/ml
0.05
20
171
41
286
1.44
1.44
1.3
1.2
—
—
—
0
0
117
956
1.24
1.42
1.2
1.2
—
—
—
0
0
21
126
1.67
1.40
1.1
1.1
—
—
—
0
0
74
573
1.30
1.39
1.2
1.2
—
—
—
0
0
49
356
1.39
1.38
1.9
2.7
—
—
—
0
0
101
815
1.25
1.37
9.3
8.9
1.54
1.33
%
0.91
101
810
6
23
2.61
1.37
1.5
1.4
—
—
—
0
0
15
82
1.84
1.35
3.6
3.6
—
—
—
0
0
40
282
1.43
1.34
2.4
2.1
134.00
128.99
g/l
0.58
27
217
20
121
1.66
1.31
5.8
3.0
59.60
54.68
%
0.54
20
111
6
24
2.50
1.30
1.2
1.3
—
—
—
0
0
6
24
2.50
1.30
1.3
1.3
—
—
—
0
0
33
472
0.69
1.29
9.9
8.8
—
—
—
0
0
98
795
1.25
1.29
7.4
7.8
24.16
24.52
mmol/l
0.43
92
755
14
77
1.82
1.25
1.1
1.2
—
13.50
—
0
10
39
278
1.41
1.25
1.5
1.3
—
—
—
0
0
6
25
2.40
1.24
13.2
3.7
46.67
41.04
umol/l
—
6
17
100
817
1.24
1.24
9.7
9.1
94.43
94.08
%
0.44
100
812
8
36
2.23
1.24
2.0
1.3
—
—
—
0
0
9
45
2.01
1.23
1.1
1.3
—
—
—
0
0
34
239
1.43
1.18
1.2
1.2
2.72
5.66
u/ml
1.16
25
94
8
38
2.11
1.18
2.9
1.9
—
—
—
0
0
21
133
1.59
1.17
3.4
3.2
—
—
—
0
0
39
282
1.39
1.17
3.9
3.4
—
—
—
0
0
18
110
1.64
1.15
1.0
1.4
—
—
—
0
0
42
310
1.36
1.12
2.0
1.7
41.14
40.13
nmol/l
0.07
42
299
96
791
1.23
1.12
3.0
3.1
130.33
128.28
g/l
0.44
90
766
34
242
1.41
1.12
1.5
1.5
—
—
—
0
0
19
119
1.60
1.11
1.5
1.7
3.78
3.77
mg/l
0.00
19
114
10
51
1.97
1.11
1.0
1.1
—
—
—
0
0
44
329
1.35
1.09
2.1
1.7
7865.49
13319.34
e6/l
0.92
37
241
8
41
1.96
1.09
1.6
1.8
—
—
—
0
0
15
89
1.69
1.07
1.3
1.4
39.23
27.35
umol/l
0.51
15
83
15
90
1.67
1.04
1.5
1.2
—
—
—
0
0
35
255
1.38
1.03
1.0
1.1
—
—
—
0
0
1427
13965
1.11
1.02
4.0
3.8
1.33
1.29
mmol/l
1.12
1304
12835
9
47
1.92
1.02
2.4
1.6
—
—
—
0
0
73
592
1.24
1.01
6.3
3.8
—
—
—
0
0
21
139
1.52
1.00
1.7
1.2
—
—
—
0
0
63
504
1.26
0.98
2.1
2.0
0.67
1.23
ug/l
1.15
52
442
60
480
1.26
0.94
2.5
3.6
0.72
0.27
g/l
0.78
35
194
326
2993
1.11
0.94
1.7
1.6
43416791.66
45400430.56
pmol/l
0.02
281
2500
7
37
1.90
0.94
2.6
1.3
56.00
25.61
%
—
7
23
33
243
1.36
0.93
1.4
1.2
—
—
—
0
0
23
159
1.45
0.91
1.3
1.5
—
—
—
0
0
19
126
1.51
0.91
1.0
1.3
—
—
—
0
0
31
227
1.37
0.90
1.5
1.5
0.39
0.33
nmol/l
0.33
26
180
64
521
1.24
0.88
6.5
4.0
24.69
24.97
mmol/l
0.29
59
493
336
3102
1.10
0.87
4.0
3.9
1.02
1.02
kg/l
0.16
45
456
33
246
1.35
0.87
1.3
1.1
—
—
—
0
0
21
144
1.46
0.87
4.5
3.7
—
—
—
0
0
75
622
1.21
0.87
2.9
3.1
25.58
25.37
mmol/l
0.20
68
597
25
178
1.41
0.86
1.4
1.8
—
1453.33
—
0
6
25
178
1.41
0.86
1.0
1.3
—
—
nmol/l
—
0
0
11
64
1.72
0.86
1.1
1.3
121.36
172.04
mmol/24h
1.65
11
64
30
221
1.36
0.85
1.4
1.4
30.40
28.55
u/l
0.09
25
182
33
247
1.34
0.85
1.5
1.6
—
—
—
0
0
34
256
1.33
0.85
1.0
1.1
—
—
—
0
0
8
46
1.74
0.82
1.1
1.2
—
—
—
0
0
23
163
1.42
0.82
2.6
1.8
32.43
32.21
pg
0.09
23
163
6
32
1.88
0.82
2.2
2.5
14.72
17.55
umol/l
—
6
32
14
89
1.58
0.81
1.1
1.2
—
—
—
0
0
29
215
1.35
0.80
1.2
1.2
—
—
—
0
0
6
33
1.82
0.79
1.0
1.1
—
—
—
0
0
318
2945
1.10
0.79
4.4
4.6
3.26
2.42
ug/l
0.43
279
2620
8
48
1.67
0.78
2.1
2.2
—
—
—
0
0
13
82
1.59
0.78
1.0
1.0
—
—
—
0
0
10
162
0.62
0.77
1.0
1.0
—
—
—
0
0
30
226
1.33
0.76
2.8
2.5
—
—
—
0
0
5
24
2.09
0.74
1.4
1.5
—
—
—
0
0
13
196
0.66
0.74
1.4
1.7
—
—
—
0
0
15
100
1.50
0.73
1.0
1.0
0.53
1.10
u/ml
—
5
37
9
56
1.61
0.72
1.2
1.6
—
—
—
0
0
9
57
1.58
0.71
1.1
1.2
—
—
—
0
0
16
109
1.47
0.71
1.1
1.5
10.52
11.91
umol/l
0.41
16
103
18
126
1.43
0.70
1.3
1.3
1638.60
1742.66
e6/l
—
10
83
7
41
1.71
0.70
1.3
1.3
—
—
—
0
0
9
58
1.55
0.69
2.6
3.2
—
—
—
0
0
37
293
1.27
0.68
4.9
3.8
2.89
2.66
mmol/l
0.27
31
201
63
530
1.20
0.67
2.3
2.1
935.80
4264.16
u/l
2.21
22
232
37
294
1.26
0.66
4.9
3.9
8.49
8.58
kpa
0.14
37
289
37
294
1.26
0.66
4.9
3.9
5.33
5.04
kpa
1.75
37
289
7
44
1.59
0.65
6.7
4.7
—
—
—
0
0
19
137
1.39
0.64
2.5
2.0
—
—
—
0
0
30
233
1.29
0.64
1.2
1.3
64.36
60.20
mmol/l
0.24
25
186
52
432
1.21
0.64
2.8
2.6
—
—
—
0
0
25
190
1.32
0.62
1.0
1.3
—
—
—
0
0
61
517
1.19
0.62
5.9
7.0
0.90
0.89
%
0.04
55
479
8
50
1.60
0.61
1.0
1.0
—
—
—
0
0
8
50
1.60
0.61
1.1
1.1
—
—
—
0
0
26
201
1.30
0.59
1.5
2.0
—
3.40
—
0
5
19
140
1.36
0.58
1.1
1.1
—
—
—
0
0
185
1700
1.10
0.57
2.8
2.8
0.61
0.74
ug/l
2.06
119
1050
20
263
0.76
0.56
4.0
2.9
8.94
7.53
mmol/l
0.57
20
254
123
1112
1.11
0.53
4.6
3.2
—
—
—
0
0
13
91
1.43
0.53
1.1
1.1
—
—
—
0
0
22
281
0.78
0.51
3.7
2.9
1.93
1.54
mmol/l
0.89
22
271
15
109
1.38
0.51
1.3
1.3
33449.29
39170.15
e6/l
—
7
59
11
75
1.47
0.50
1.2
1.3
111.18
132.59
nmol/l
0.84
11
75
6
41
1.46
0.50
1.5
1.6
—
—
—
0
0
60
522
1.15
0.48
5.9
6.9
1.74
1.56
%
0.54
53
485
32
263
1.22
0.47
2.6
2.4
16.83
16.28
%
0.35
20
137
29
236
1.23
0.46
1.1
1.0
—
—
—
0
0
7
48
1.46
0.46
3.3
10.9
—
—
—
0
0
21
164
1.28
0.46
1.8
1.6
39.31
60.88
%
1.58
16
103
11
77
1.43
0.45
1.0
1.0
—
—
—
0
0
70
619
1.14
0.45
1.1
1.1
—
—
—
0
0
7
51
1.37
0.44
3.0
2.7
—
—
—
0
0
35
413
0.84
0.41
1.3
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
260.38
—
0
8
0
16
0.00
0.41
0.0
1.5
—
9.00
—
0
7
14
105
1.34
0.41
1.6
2.3
12.41
10.52
%
0.86
14
105
0
18
0.00
0.40
0.0
1.2
—
1.87
—
0
18
0
18
0.00
0.40
0.0
3.3
—
1.08
—
0
13
14
106
1.32
0.39
1.1
1.0
—
—
—
0
0
9
69
1.31
0.37
2.7
2.6
57688.89
38063.84
ug/l
—
9
69
525
5414
0.96
0.36
2.6
2.7
—
—
—
0
0
11
146
0.75
0.36
1.5
2.1
—
—
—
0
0
36
311
1.16
0.34
1.4
1.5
—
—
—
0
0
11
82
1.34
0.34
1.4
1.9
—
—
—
0
0
87
948
0.91
0.33
1.5
1.4
—
—
—
0
0
15
118
1.27
0.33
1.7
1.6
40.57
34.08
%
—
10
72
63
697
0.90
0.33
3.6
3.2
—
—
—
0
0
52
465
1.12
0.31
4.7
3.6
1.43
1.36
mmol/l
0.18
52
460
21
175
1.20
0.30
2.3
2.5
—
—
—
0
0
7
55
1.27
0.30
3.7
2.3
101.14
143.31
nmol/l
—
7
49
7
57
1.23
0.29
3.4
1.6
—
—
—
0
0
46
414
1.11
0.26
1.5
1.5
94.68
213.96
pmol/l
1.66
46
405
5
72
0.69
0.26
2.0
1.4
146.60
425.81
u/l
—
5
67
142
1490
0.95
0.22
1.3
1.3
—
—
—
0
0
30
337
0.89
0.22
6.3
4.1
—
—
—
0
0
5
41
1.22
0.22
1.4
1.7
—
—
—
0
0
5
42
1.19
0.21
1.6
1.5
—
—
—
0
0
102
964
1.06
0.21
2.9
2.9
—
—
—
0
0
30
335
0.89
0.21
1.8
2.3
254.72
132.74
ug/min
0.21
17
208
0
13
0.00
0.21
0.0
1.1
—
0.23
—
0
5
6
51
1.18
0.19
1.0
1.0
123.88
174.47
iu/ml
—
6
51
17
146
1.17
0.19
2.1
2.5
0.74
1.30
g/24h
—
10
67
19
165
1.15
0.19
1.2
1.2
—
—
—
0
0
13
109
1.19
0.18
1.5
1.4
—
—
—
0
0
27
242
1.12
0.18
1.2
1.1
41.34
139.38
iu/ml
—
7
53
33
300
1.10
0.17
1.3
1.4
—
—
—
0
0
27
243
1.11
0.17
1.3
1.5
—
—
—
0
0
13
110
1.18
0.17
2.0
1.5
0.97
0.97
g/l
0.02
13
110
16
139
1.15
0.16
1.9
1.4
14290.09
77400.54
e6/l
0.72
11
100
8
72
1.11
0.16
1.9
1.3
140.35
160.57
pmol/l
—
8
72
40
370
1.08
0.16
1.9
2.4
—
—
—
0
0
33
303
1.09
0.15
1.4
1.4
—
—
—
0
0
20
178
1.13
0.15
2.4
1.8
—
—
—
0
0
67
637
1.05
0.13
1.5
1.8
—
—
—
0
0
27
294
0.92
0.13
1.3
1.9
0.79
0.81
nmol/l
0.07
20
244
145
1406
1.03
0.13
3.3
4.3
101.16
24.75
ug/l
0.47
115
1144
11
95
1.16
0.11
1.8
1.4
1.60
1.58
g/l
0.06
11
95
170
1741
0.97
0.10
4.7
4.4
32.49
32.41
%
0.03
128
1181
16
144
1.11
0.10
1.6
1.3
283.00
278.94
mosm/kgh2o
0.33
11
109
14
155
0.90
0.09
3.3
2.3
—
—
—
0
0
17
185
0.92
0.08
1.1
1.1
—
—
—
0
0
5
64
0.78
0.08
1.6
1.3
—
—
—
0
0
7
68
1.03
0.07
1.9
2.9
—
—
—
0
0
7
68
1.03
0.07
1.6
1.4
—
—
—
0
0
54
520
1.04
0.07
5.5
4.3
—
—
—
0
0
16
148
1.08
0.06
2.7
2.7
—
—
—
0
0
13
121
1.07
0.03
1.2
1.1
—
—
—
0
0
31
300
1.03
0.03
3.3
3.5
27.78
24.36
mg/l
0.24
18
186
21
203
1.03
0.01
1.9
1.8
1.50
1.64
mmol/l
0.41
21
198
16
166
0.96
0.00
1.3
1.1
—
—
—
0
0
48
486
0.99
0.00
2.2
3.5
246.28
2863.54
u/ml
0.69
39
420
11
105
1.05
0.00
1.5
1.3
—
—
—
0
0
11
105
1.05
0.00
1.6
1.5
70.64
78.80
umol/l
0.63
11
105
10
98
1.02
0.00
1.0
1.1
—
—
—
0
0
12
118
1.02
0.00
1.2
1.5
—
—
—
0
0
6
68
0.88
-0.00
1.2
1.4
31.25
31.99
nmol/l
—
6
55
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
51
0.98
-0.00
2.2
3.4
6.95
7.21
mg/l
—
5
40
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
282.20
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
335.00
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
13.77
—
0
9
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_ORBIT and mortality.

Females

Parameter HR [95% CI] p-value
H7_ORBIT 1.329 [1.18, 1.49] < 0.001
Birth year 0.993 [0.98, 1.0] 0.125

During the follow-up period (1.1.1998 — 31.12.2019), 737 out of 5877 females with H7_ORBIT died.

Males

Parameter HR [95% CI] p-value
H7_ORBIT 1.431 [1.24, 1.65] < 0.001
Birth year 0.989 [0.98, 1.0] 0.018

During the follow-up period (1.1.1998 — 31.12.2019), 575 out of 3310 males with H7_ORBIT died.

Mortality risk

Mortality risk for people of age

years, who have H7_ORBIT.

N-year risk Females Males
1 0.149% 0.331%
5 0.859% 1.848%
10 1.888% 4.304%
15 3.475% 8.147%
20 6.072% 13.883%

Relationships between endpoints

Index endpoint: H7_ORBIT – Disorders of orbit

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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