Food allergy

FOOD_ALLERGY

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L23.6 Cause of death: ICD-10 — L23.6 2 out of 7 registries used, show all original rules.	108
4. Check minimum number of events None	108
5. Include endpoints None	108
6. Filter based on genotype QC (FinnGen only)	105

Control definitions (FinnGen only)

Control exclude: ASTHMA_ALLERG

Extra metadata

First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L23
Name in latin: Eczema allergicum ex contactu nutrimentorum

NAME	FOOD_ALLERGY
CONTROL_EXCLUDE	ASTHMA_ALLERG
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L236
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L236
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Food allergy based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1444	806	635
Only index persons	1161	681	480
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.02
Only index persons	0.02	0.03	0.02
Median age at first event (years)
Whole population	15.11	23.09	4.90
Only index persons	19.59	26.47	9.83

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	105	80	25
Unadjusted period prevalence (%)	0.02	0.03	0.01
Median age at first event (years)	34.54	36.08	29.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
108: Matched controls
1080

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L23.6

ICD-10 Finland

Allergic contact dermatitis due to food in contact with skin

+∞

155.8

108

Z01.5

ICD-10 Finland

Diagnostic skin and sensitization tests

13.2

39.3

XQ800

NOMESCO Finland

Prick test

11.5

29.2

C01CA24

ATC

epinephrine; parenteral

8.9

21.9

L20.0

ICD-10 Finland

Besnier prurigo

7.5

20.4

J30.10

ICD-10 Finland

Allergic rhinitis due to pollen

6.7

12.2

E0000UV, ,

ATC

4.0

10.9

343

E000002, ,

ATC

4.6

10.6

L23.9

ICD-10 Finland

Allergic contact dermatitis, unspecified cause

44.5

10.2

L20.9

ICD-10 Finland

Atopic dermatitis, unspecified

9.6

9.9

D07AC13

ATC

mometasone; topical

3.6

9.2

180

XQ802

NOMESCO Finland

Epicutan test

8.8

8.6

R06AE09

ATC

levocetirizine; oral

4.0

8.6

E000001, ,

ATC

3.4

8.1

159

T78.4

ICD-10 Finland

Allergy, unspecified

6.5

7.5

H02AB06

ATC

prednisolone; systemic

3.0

7.1

313

J30.3

ICD-10 Finland

Other allergic rhinitis

7.7

6.8

R06AX27

ATC

desloratadine; oral

2.9

6.5

236

L23.2

ICD-10 Finland

Allergic contact dermatitis due to cosmetics

15.6

6.5

J45.9

ICD-10 Finland

Asthma, unspecified

3.3

6.3

103

J45.0

ICD-10 Finland

Predominantly allergic asthma

4.4

6.3

D07AC01

ATC

betamethasone; topical

2.8

6.0

214

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3018001) Oat IgE Ab [Units/volume] in Serum

+∞

5.24

1.2

0.0

0.55

—

u/ml

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

5.13

4.54

3.5

136.23

132.32

g/l

0.30

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

5.44

4.13

3.2

2.9

0.72

0.61

0.66

(3027273) Bicarbonate [Moles/volume] in Venous blood

4.30

3.17

4.3

2.4

24.57

23.82

mmol/l

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

4.13

3.07

5.4

3.0

48.89

52.37

—

(1761482) Bacteria [#/volume] in Urine by Culture

5.67

2.92

6.6

2.8

—

(3008037) Lactate [Moles/volume] in Venous blood

5.67

2.92

4.0

2.5

1.34

1.19

mmol/l

—

(3038515) Glucose [Moles/volume] in Venous blood

5.67

2.92

4.0

2.5

6.20

6.78

mmol/l

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

771

2.48

2.81

2.9

3.3

1.19

1.25

mmol/l

0.42

723

(44813793) Dust mix specific IgE antibody measurement

8.66

2.77

1.2

—

(3005322) IgE [Units/volume] in Serum or Plasma

2.60

2.3

1.3

470.61

481.42

u/ml

0.01

(3012544) pH of Venous blood

2.56

2.52

4.6

4.8

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

808

2.46

2.47

3.1

3.5

1.51

1.49

mmol/l

0.13

763

(3000492) Spirometry study

2.40

2.46

1.0

1.4

—

(3035285) Chloride [Moles/volume] in Venous blood

5.76

2.24

3.4

2.4

107.80

105.78

mmol/l

—

(3041354) Potassium [Moles/volume] in Venous blood

5.76

2.24

3.4

2.4

3.76

3.88

mmol/l

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

5.76

2.24

3.4

2.4

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

818

2.34

2.23

3.5

3.8

2.85

2.83

mmol/l

0.07

773

(3000494) Fungus identified in Specimen by Culture

2.13

1.93

1.8

1.7

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

700

1.80

4.1

3.9

14.34

14.51

pmol/l

0.30

646

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

324

1.67

1.77

3.6

3.4

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

2.81

1.61

1.1

1.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

259

1.65

1.60

3.2

3.0

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.24

1.50

1.6

1.2

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.16

1.50

3.6

7.6

103.58

104.64

mmol/l

0.30

(3035350) Ketones [Presence] in Urine by Test strip

423

1.55

1.43

3.6

3.3

0.00

estimate

-0.00

104

(3021601) Nitrite [Presence] in Urine by Test strip

423

1.55

1.43

6.0

4.5

0.00

estimate

-0.00

101

(3030905) Polymorphonuclear cells [#/volume] in Blood

3.03

1.37

2.4

5.0

3.93

4.27

e9/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

3.03

1.37

2.4

5.9

57.60

60.06

—

(3041096) Erythrocytes [Presence] in Urine by Automated

251

1.58

1.35

4.1

3.2

—

(3009261) Glucose [Presence] in Urine by Test strip

429

1.52

1.31

3.6

3.3

0.00

estimate

-0.00

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

900

1.96

1.21

12.5

11.6

15.19

20.06

mg/l

0.97

671

(40768443) Skin Pathology biopsy report

2.38

1.20

1.2

—

(4034850) Laboratory test

2.57

1.16

3.8

5.8

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

789

1.62

1.13

9.3

9.7

90.73

93.51

ml/min/173m2

0.54

623

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.34

1.12

2.9

2.0

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

114

1.69

1.11

3.3

2.4

2.85

0.83

e6/l

0.75

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

2.45

1.10

1.0

1.2

—

(3019198) Lymphocytes [#/volume] in Blood

471

1.45

1.07

6.1

5.7

1.94

2.15

e9/l

0.68

433

(3007853) Bacteria identified in Skin by Aerobe culture

1.75

1.07

2.0

1.7

—

(3022621) pH of Urine by Test strip

1.98

1.05

4.4

2.0

—

(3002582) Erythrocytes [#/volume] in Urine

237

1.50

1.05

3.5

3.0

17.38

313.38

e6/l

0.56

183

(42529406) Shigella sp [Presence] in Stool by Culture

2.33

1.04

1.0

1.2

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

2.33

1.04

1.2

1.1

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

2.33

1.04

1.2

1.4

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.33

1.04

1.0

1.2

—

(3030467) Casts [#/volume] in Urine by Automated count

213

1.49

0.99

3.7

2.7

0.30

0.26

e6/l

0.10

162

(3007164) IgA [Mass/volume] in Serum or Plasma

233

1.46

0.94

2.0

1.3

2.55

2.13

g/l

0.76

143

(3006315) Basophils [#/volume] in Blood

450

1.40

0.93

6.1

5.6

0.04

e9/l

0.26

408

(3001604) Monocytes [#/volume] in Blood

450

1.40

0.93

6.1

5.6

0.55

0.54

e9/l

0.10

409

(1761868) Lipid panel - Serum or Plasma

335

1.42

0.93

2.0

2.4

—

(40768797) Stomach Pathology biopsy report

1.67

0.93

1.0

1.2

—

(3013115) Eosinophils [#/volume] in Blood

471

1.39

0.91

6.0

6.4

0.20

0.19

e9/l

0.34

430

(3022217) INR in Platelet poor plasma by Coagulation assay

273

1.42

0.87

5.7

6.8

1.10

1.04

inr

0.20

(3023368) Bacteria identified in Blood by Culture

174

1.49

0.87

2.5

4.1

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.99

0.86

2.0

1.5

—

(3002385) Erythrocyte distribution width [Ratio]

805

1.50

0.85

12.7

13.7

13.92

14.28

0.38

793

(3003338) MCHC [Mass/volume]

816

1.52

0.85

12.6

14.2

333.29

333.44

g/l

0.05

811

(3021440) Promyelocytes/100 leukocytes in Blood

1.80

0.83

3.7

4.7

—

0.07

—

(3000991) Gas panel - Venous blood

1.72

0.80

5.0

10.4

—

(3019060) Gas panel - Arterial blood

1.86

0.80

3.7

18.7

—

(3021589) Normoblasts [#/volume] in Blood

410

1.36

0.79

8.7

7.3

0.00

e9/l

0.50

335

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

109

1.55

0.76

3.6

2.6

3.60

4.45

e6/l

0.16

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.13

0.75

1.0

1.1

—

(3000330) Specific gravity of Urine by Test strip

1.90

0.75

6.6

1.9

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.85

0.74

1.6

1.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

772

1.40

0.70

3.7

3.9

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

1.89

0.69

1.2

1.3

—

12.96

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

526

1.32

0.68

8.3

9.8

3.63

3.96

e9/l

0.96

476

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

618

1.32

0.66

7.4

7.0

80.14

74.80

u/l

0.53

575

(3018095) Leukocytes [#/volume] in Urine

286

1.33

0.64

4.2

3.4

11.13

39.41

e6/l

1.17

194

(40760892) CBC W Ordered Manual Differential panel - Blood

422

1.29

0.62

6.1

6.3

—

(3003694) ABO and Rh group [Type] in Blood

298

1.31

0.60

1.7

1.6

—

(3020682) Albumin/Creatinine [Ratio] in Urine

169

1.38

0.59

4.9

3.4

4.32

10.10

mg/mmol

0.82

104

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

1.76

0.59

1.2

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

234

1.33

0.58

2.0

2.3

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.66

0.56

4.3

6.0

22.82

23.59

mmol/l

—

(21494755) Public health laboratory ask at order entry panel

117

1.43

0.56

1.2

1.4

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

1.54

0.56

1.1

1.7

—

(3025159) Blasts/100 leukocytes in Blood

1.54

0.56

4.0

4.5

—

0.06

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.57

0.54

1.4

—

(36660697) Celiac disease serology panel - Serum

101

1.44

0.52

1.2

1.1

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

117

0.66

0.49

1.5

1.8

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

175

1.32

0.48

1.1

1.3

34.97

24.66

iu/ml

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.49

0.48

1.0

1.1

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

940

1.46

0.47

8.8

26.46

25.58

u/l

0.22

908

(40761535) Cells panel - Urine sediment

1.46

0.47

1.1

3.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

289

1.26

0.46

1.9

1.7

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

215

1.28

0.43

1.8

2.1

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.64

0.43

2.8

2.1

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

114

1.37

0.43

1.4

1.7

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.4

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.4

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.41

0.0

1.0

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.41

0.0

2.8

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.40

0.0

1.0

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

162

1.29

0.39

1.4

1.6

—

(3037467) Urinalysis macro (dipstick) panel - Urine

590

1.21

0.39

4.3

4.2

—

(3022145) Colonoscopy Study observation

1.40

0.38

1.1

1.4

—

(40761511) CBC panel - Blood by Automated count

946

1.39

0.37

10.9

10.3

—

(4200892) Spirometry reversibility

1.45

0.36

1.0

1.3

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.38

0.35

2.5

1.2

—

(3013512) EKG study

184

1.25

0.34

4.8

3.1

—

(3044889) 12 lead EKG panel

516

1.18

0.32

2.9

—

(40768804) Tissue Pathology biopsy report

320

1.19

0.31

1.9

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

140

0.76

0.30

1.7

2.0

—

(3012516) Albumin [Mass/volume] in Urine

159

1.24

0.29

4.7

2.9

28.11

66.09

mg/l

0.68

101

(40758558) Short blood count panel - Blood

236

1.19

0.28

4.9

7.4

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.25

0.28

1.1

1.0

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

246

1.19

0.27

4.3

2.6

9.86

20.99

ng/l

1.90

124

(36304419) Bacteria [Presence] in Urine

218

1.19

0.26

4.2

2.7

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.37

0.24

1.0

1.1

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

182

1.19

0.23

2.2

3.1

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

1.26

0.23

1.6

9.1

24.06

24.51

mmol/l

—

(3011288) Drugs identified in Urine by Screen method

1.20

0.22

2.0

1.9

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.6

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.21

0.0

1.5

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.0

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.2

—

(40763324) Parainfluenza virus 1 RNA [Presence] in Isolate by NAA with probe detection

0.00

0.21

0.0

1.3

—

(40763470) Parainfluenza virus 4 RNA [Presence] in Isolate by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.21

0.0

1.5

—

13.44

—

(3044941) Cell count panel - Synovial fluid

0.00

0.21

0.0

1.7

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

153.38

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.21

0.0

1.1

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.8

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

401

0.88

0.20

2.4

2.8

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.20

0.0

2.1

—

8.17

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.20

0.0

1.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

262

1.15

0.20

2.1

1.8

103.94

93.91

pmol/l

0.57

130

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.21

0.20

1.0

1.5

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

1.19

0.20

1.7

1.4

—

(3005033) Fetal Nuchal fold Thickness US

1.19

0.20

1.7

1.4

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

303

1.13

0.18

5.5

8.2

1.22

mmol/l

0.03

279

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

1.14

0.17

3.4

4.4

—

21.61

—

(3016879) Cocaine [Presence] in Urine

0.72

0.17

2.0

1.6

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

1.21

0.17

2.1

1.9

—

(3044640) Blood type and Crossmatch panel - Blood

254

0.88

0.16

1.7

2.4

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

305

0.89

0.16

1.9

2.1

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

256

1.13

0.16

1.2

1.3

6.69

1.18

u/ml

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.77

0.16

1.3

1.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

237

1.13

0.16

1.6

1.8

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.21

0.14

1.3

1.5

—

(3042936) Bacteria identified in Isolate by Culture

113

1.17

0.14

1.8

2.5

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

109

0.81

0.13

2.1

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

114

1.16

0.12

1.7

4.6

0.84

0.82

mmol/l

0.47

105

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

176

0.89

0.10

1.3

1.22

7.34

u/ml

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.14

0.10

2.0

8.5

23.30

24.68

mmol/l

—

(3022313) Gas panel - Capillary blood

1.14

0.10

1.6

11.7

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.16

0.10

1.6

1.5

—

(40761536) Microorganisms panel - Urine sediment

1.16

0.10

2.3

3.2

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

1.04

0.09

1.2

1.6

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

1.14

0.09

1.7

1.5

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

1.04

0.08

1.7

1.4

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

1.04

0.08

1.7

1.4

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

1.04

0.08

1.7

1.4

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

1.04

0.08

1.7

1.4

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

1.10

0.08

1.6

—

(3027944) Amphetamines [Presence] in Urine

0.81

0.08

1.8

1.6

—

(3000764) Benzodiazepines [Presence] in Urine

0.81

0.08

1.8

1.6

—

(3028300) Cannabinoids [Presence] in Urine

0.81

0.08

1.8

1.6

—

(3027008) Opiates [Presence] in Urine

0.81

0.08

1.8

1.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.07

0.07

2.9

2.8

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.87

0.07

3.4

4.9

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

0.83

0.07

1.9

1.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

0.82

0.07

2.0

1.8

—

(3026008) Bacteria identified in Urine by Culture

233

0.93

0.06

2.4

2.5

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

737

1.06

0.05

4.1

4.2

38.64

37.95

mmol/mol

0.27

695

(3017143) Hepatitis C virus Ab [Presence] in Serum

161

0.92

0.05

1.5

—

(3029937) Albumin [Presence] in Urine by Test strip

229

1.06

0.04

2.4

3.7

0.00

estimate

-0.00

(3019832) Treponema pallidum Ab [Presence] in Serum

196

0.96

0.00

1.5

1.8

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

226

0.97

0.00

1.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

185

0.97

0.00

1.7

2.4

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

114

0.96

0.00

1.7

1.6

—

(3002256) Pathology report gross observation

101

0.99

0.00

1.2

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.0

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.1

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3008898) HLA-B27 [Presence]

1.02

-0.00

1.0

1.1

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.96

-0.00

1.0

1.7

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

22.18

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

120

1.00

-0.00

2.3

1.9

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.98

-0.00

1.5

1.9

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

-0.00

0.0

1.0

—

104.00

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.4

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

1.50

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

11.26

—

(3012565) Volume of 24 hour Urine

0.00

-0.00

0.0

1.0

—

2259.00

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.3

—

92.38

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

4.0

—

2.94

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.0

—

7.03

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3004959) Base excess in Arterial cord blood by calculation

0.00

-0.00

0.0

1.0

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

-0.00

0.0

1.5

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

0.29

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.2

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

-0.00

0.0

1.2

—

154.83

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

1.2

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

6.8

—

128.00

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

1.5

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.0

—

5.82

—

(3021788) Differential panel - Synovial fluid

0.00

-0.00

0.0

1.6

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.0

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3025941) Bacteria identified in Stool by Culture

1.00

-0.00

1.0

1.3

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

0.87

—

(3006598) pH of Arterial cord blood

0.00

-0.00

0.0

1.0

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3045716) Anion gap in Serum or Plasma

0.00

-0.00

0.0

2.0

—

8.00

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.1

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

3.0

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

3.0

—

(4035726) Immunohistochemistry procedure

0.84

-0.00

1.0

1.4

—

(3019225) pH of Specimen

1.00

-0.00

3.8

5.1

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

2.43

—

Mortality – FinRegistry

↥

Association

Association between endpoint FOOD_ALLERGY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have FOOD_ALLERGY.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: FOOD_ALLERGY – Food allergy

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Food allergy

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints