Supernumerary teeth EXCLUDE clefts and syndromes

K11_SUPNUM_ONLY

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions not K11_SUPNUM_EXCLUDE	519486
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — K00.1 Cause of death: ICD-10 — K00.1 2 out of 7 registries used, show all original rules.	163
4. Check minimum number of events None	163
5. Include endpoints None	163
6. Filter based on genotype QC (FinnGen only)	157

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze: DF5

NAME	K11_SUPNUM_ONLY
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS	!K11_SUPNUM_EXCLUDE
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	K001
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	K001
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Supernumerary teeth EXCLUDE clefts and syndromes based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	3723	1455	2264
Only index persons	3237	1262	1975
Unadjusted period prevalence (%)
Whole population	0.05	0.04	0.06
Only index persons	0.06	0.05	0.08
Median age at first event (years)
Whole population	10.23	10.55	9.98
Only index persons	10.76	11.25	10.45

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	157	84	73
Unadjusted period prevalence (%)	0.03	0.03	0.03
Median age at first event (years)	14.44	14.61	14.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
163: Matched controls
1630

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

K00.10

ICD-10 Finland

The incisor and canine region, including the mesiodens

1183.4

110.8

K00.11

ICD-10 Finland

Excess teeth in the premolar region

+∞

25.7

K00.19

ICD-10 Finland

Indefinite redundant teeth

139.7

23.3

EBA10

NOMESCO Finland

Operative extraction of tooth

4.9

23.0

295

K00.12

ICD-10 Finland

Excess teeth in the molar region

+∞

22.4

WZC10

NOMESCO Finland

Written specialist consultation based on a referral from a dentist or a physician

9.6

21.2

EBA12

NOMESCO Finland

Demanding operative extraction of tooth

5.0

11.8

EB1AI

NOMESCO Finland

Cone beam imaging of teeth and jaws (one quarter)

18.2

10.1

K00.1

ICD-10 Finland

Supernumerary teeth

+∞

9.5

SAA04

NOMESCO Finland

Special examination of mouth

3.9

8.8

SXB00

NOMESCO Finland

Removal of sutures from oral mucosa

4.6

8.6

K01.0

ICD-10 Finland

Embedded teeth

6.4

7.2

ECA00

NOMESCO Finland

Surgical exposure of tooth

18.9

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3022217) INR in Platelet poor plasma by Coagulation assay

340

2.04

4.27

7.9

6.0

1.07

inr

0.01

119

(3021788) Differential panel - Synovial fluid

7.25

3.40

1.1

1.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

577

1.80

3.37

7.6

7.7

—

(3007853) Bacteria identified in Skin by Aerobe culture

130

2.19

3.01

1.6

—

(3016616) Dehydroepiandrosterone sulfate (DHEA-S) [Moles/volume] in Serum or Plasma

5.57

2.90

2.1

1.3

4.39

5.17

umol/l

—

(3044640) Blood type and Crossmatch panel - Blood

349

1.77

2.78

2.7

2.4

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

100

2.26

2.73

14.7

6.6

1.13

1.39

mmol/l

0.16

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

2.80

2.69

1.2

1.70

4.00

u/ml

—

(3042936) Bacteria identified in Isolate by Culture

129

2.11

2.68

2.0

2.1

—

(40761511) CBC panel - Blood by Automated count

150

1341

2.49

2.66

12.9

8.5

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

2.74

2.60

1.1

1.5

5.60

4.08

mg/l

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

5.61

2.56

1.5

7.6

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

444

1.68

2.56

3.1

2.7

71.94

70.33

nmol/l

0.15

405

(3013650) Neutrophils [#/volume] in Blood by Automated count

716

1.65

2.54

8.7

8.8

3.82

4.06

e9/l

0.57

615

(3013115) Eosinophils [#/volume] in Blood

639

1.65

2.53

7.7

7.6

0.19

e9/l

0.00

570

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

281

1.78

2.53

2.9

2.5

19.63

37.29

ng/l

0.45

118

(3001604) Monocytes [#/volume] in Blood

622

1.64

2.49

7.6

7.0

0.54

0.55

e9/l

0.12

539

(3006315) Basophils [#/volume] in Blood

622

1.64

2.49

7.8

7.0

0.04

e9/l

0.22

540

(3005719) IgG [Mass/volume] in Serum or Plasma

2.23

2.44

2.2

3.2

10.92

9.87

g/l

0.31

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

6.40

2.39

4.8

3.0

69.00

45.25

umol/l

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

3.34

2.34

2.6

1.8

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

114

2.07

2.34

1.1

1.3

—

(3019198) Lymphocytes [#/volume] in Blood

662

1.59

2.24

7.7

6.8

2.09

2.03

e9/l

0.28

596

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

142

1265

1.95

2.18

15.7

10.2

18.58

20.66

mg/l

0.35

114

918

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.38

2.14

1.8

1.9

—

(3021440) Promyelocytes/100 leukocytes in Blood

2.26

2.05

2.3

5.4

0.20

0.25

—

(3028026) IgM [Mass/volume] in Serum or Plasma

2.20

2.04

1.5

2.1

1.16

0.97

g/l

0.48

(3022313) Gas panel - Capillary blood

2.20

2.04

17.9

7.3

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

4.65

1.95

1.2

1.3

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

3.85

1.95

1.3

1.5

—

(1761868) Lipid panel - Serum or Plasma

411

1.55

1.84

2.3

2.0

—

(4034850) Laboratory test

3.13

1.82

2.0

8.7

—

(3044290) Cell count panel - Cerebral spinal fluid

2.85

1.81

1.5

4.0

—

(3024731) MCV [Entitic volume]

157

1485

2.55

1.75

20.6

14.2

88.89

88.79

0.11

157

1469

(3035941) MCH [Entitic mass]

157

1485

2.55

1.75

20.6

14.2

29.77

29.82

0.14

157

1468

(3013707) Erythrocyte sedimentation rate by Westergren method

806

1.50

1.75

6.0

3.7

7.40

8.05

mm/h

0.30

747

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

266

1.61

1.73

2.9

2.4

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

3.93

1.73

3.2

6.3

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

151

1.77

1.72

1.3

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

546

1.49

1.71

3.3

2.7

—

(3017181) Myelocytes/100 leukocytes in Blood

2.07

1.70

2.3

5.2

1.20

0.93

—

(3002256) Pathology report gross observation

113

1.88

1.69

1.3

1.2

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

445

1.51

1.69

12.8

8.6

1.22

mmol/l

0.09

389

(3002179) Metamyelocytes/100 leukocytes in Blood

2.09

1.65

2.5

4.8

0.60

0.54

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

1.95

1.63

3.8

2.7

30.92

30.63

0.04

(3023368) Bacteria identified in Blood by Culture

203

1.65

1.61

4.4

4.6

—

(3000963) Hemoglobin [Mass/volume] in Blood

157

1486

2.53

1.61

20.8

14.5

137.04

138.09

g/l

0.41

157

1470

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

3.07

1.59

3.0

1.7

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

111

960

1.49

1.56

4.7

3.6

14.27

14.59

pmol/l

0.82

104

870

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

127

1133

1.55

1.50

4.9

4.1

1.91

1.80

mu/l

0.55

118

1067

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.30

1.49

1.7

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

2.48

1.41

4.1

4.6

46.71

53.62

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

2.48

1.41

4.1

4.5

3.04

3.71

e9/l

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.86

1.39

22.4

12.7

24.63

24.83

mmol/l

0.09

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

2.11

1.36

4.4

3.5

1.22

1.23

mmol/l

0.21

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

119

0.40

1.30

1.2

2.5

2.41

mmol/l

—

106

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

116

1029

1.44

1.29

3.1

2.8

5.41

5.57

mmol/l

0.81

109

944

(3000991) Gas panel - Venous blood

100

1.78

1.29

11.0

13.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

294

1.48

1.27

1.7

1.5

100.43

95.75

pmol/l

0.24

157

(3013512) EKG study

193

1.54

1.19

3.9

2.4

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

121

1089

1.43

1.18

3.5

3.1

2.64

2.82

mmol/l

1.68

116

1024

(3017143) Hepatitis C virus Ab [Presence] in Serum

272

1.47

1.17

1.9

1.6

—

(3027315) Oxygen [Partial pressure] in Blood

2.55

1.16

5.0

4.3

9.42

9.48

kpa

—

(3013290) Carbon dioxide [Partial pressure] in Blood

2.55

1.16

5.0

4.3

5.22

4.97

kpa

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

1.78

1.16

1.3

1.5

321.00

279.64

miu/ml

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.31

1.12

1.4

1.5

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

1.93

1.10

4.6

5.6

89.00

94.95

0.33

(4035726) Immunohistochemistry procedure

1.85

1.08

1.3

1.6

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

780

1.34

1.06

10.1

6.1

93.09

81.73

u/l

1.11

731

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.11

1.04

9.0

18.2

0.60

0.66

—

(3002032) Base excess in Venous blood by calculation

108

1.64

1.01

10.0

8.2

0.87

1.77

mmol/l

0.44

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.04

1.01

9.0

17.7

0.97

1.77

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

2.21

0.98

2.0

1.6

—

(1616796) Gas panel - Central venous blood

2.21

0.98

4.2

4.4

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.75

0.98

11.4

10.5

24.16

23.72

mmol/l

0.19

(3012544) pH of Venous blood

109

1.62

0.98

10.0

8.4

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

140

1310

1.49

0.96

11.5

7.8

27.81

26.74

u/l

0.24

135

1268

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

1.81

0.96

2.6

1.5

3.42

3.64

ug/l

—

(3047181) Lactate [Moles/volume] in Blood

0.00

0.96

0.0

19.3

—

1.24

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

114

1032

1.35

0.95

11.0

8.0

103.91

101.59

ml/min/173m2

0.49

790

(3014148) Varicella zoster virus Ab [Titer] in Serum

1.93

0.95

1.1

1.2

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

103

0.47

0.93

2.4

1.6

—

(3052851) Hemolysis interference index of Serum or Plasma

2.19

0.92

3.3

2.7

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.19

0.92

1.7

1.4

—

(3002385) Erythrocyte distribution width [Ratio]

128

1183

1.38

0.91

15.5

12.9

14.05

13.73

0.36

128

1166

(3003327) Ova and parasites identified in Stool by Light microscopy

1.77

0.88

2.1

1.4

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

2.04

0.88

2.5

2.8

64.25

49.94

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

497

0.74

0.87

2.1

1.7

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

352

1.34

0.86

5.2

3.7

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.82

0.85

2.0

1.2

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

147

1.49

0.85

2.3

2.0

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

115

1.53

0.80

1.4

1.3

168.88

112.77

iu/ml

—

(3018418) pH of Serum or Plasma

256

1.36

0.78

4.9

3.6

7.41

7.40

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

275

1.35

0.77

2.4

3.1

—

(3029937) Albumin [Presence] in Urine by Test strip

303

1.33

0.76

3.9

3.3

0.18

0.01

estimate

0.44

115

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

2.03

0.73

2.2

1.4

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

2.03

0.73

2.4

2.3

92.00

267.22

ug/l

—

(3022145) Colonoscopy Study observation

101

1.53

0.73

1.9

1.5

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

1.78

0.72

1.1

1.6

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

1.95

0.71

1.2

1.0

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.70

0.69

1.6

2.0

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

1.88

0.69

1.4

1.1

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

1.88

0.69

1.0

1.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.56

0.68

2.2

2.3

—

(40768804) Tissue Pathology biopsy report

383

1.28

0.68

2.4

1.8

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

1.81

0.66

1.0

1.2

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

1.62

0.66

1.3

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

1.75

0.64

2.2

2.6

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

175

1.37

0.62

2.2

3.4

0.78

0.84

e6/l

0.04

108

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

1.60

0.61

1.8

1.9

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.60

0.0

1.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

437

1.24

0.59

2.0

1.8

—

(3019225) pH of Specimen

1.41

0.51

8.4

3.5

—

(3002582) Erythrocytes [#/volume] in Urine

311

1.25

0.51

4.4

3.7

7.73

57.94

e6/l

1.64

241

(3030467) Casts [#/volume] in Urine by Automated count

283

1.25

0.50

2.8

3.8

0.21

0.26

e6/l

0.20

214

(3000494) Fungus identified in Specimen by Culture

102

1.41

0.49

2.0

—

(3003338) MCHC [Mass/volume]

128

1218

1.24

0.48

16.0

12.4

334.26

335.12

g/l

0.57

128

1205

(4200892) Spirometry reversibility

1.50

0.48

1.1

1.4

—

(3044889) 12 lead EKG panel

642

1.19

0.47

2.0

2.6

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

1.42

0.45

3.0

1.5

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.48

0.45

1.0

1.3

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

440

0.82

0.45

3.1

2.5

—

(3045414) Leukocytes [Presence] in Urine

1.39

0.44

1.0

1.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

597

1.18

0.43

5.1

4.4

0.00

estimate

-0.00

117

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

1.42

0.43

3.9

2.0

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

105

1.36

0.42

1.3

1.8

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.58

0.42

1.0

1.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

150

1.30

0.42

1.7

1.9

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

132

1.32

0.42

3.0

2.6

2480.17

3324.99

u/l

0.16

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

1.53

0.41

3.2

1.3

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.3

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.3

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.6

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.2

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.39

0.41

7.3

8.1

104.83

104.00

mmol/l

0.20

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

289

0.80

0.41

3.4

2.1

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

1.40

0.38

1.0

1.1

—

(3009508) Creatinine [Moles/volume] in Urine

302

1.20

0.38

4.1

3.7

7.54

8.68

mmol/l

0.76

277

(3021589) Normoblasts [#/volume] in Blood

597

0.86

0.37

12.3

8.9

0.00

e9/l

0.62

477

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

181

1.25

0.37

1.4

1.3

10.27

23.61

iu/ml

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.44

0.36

1.7

1.9

—

(3007164) IgA [Mass/volume] in Serum or Plasma

400

1.17

0.35

1.6

1.5

2.14

2.00

g/l

0.40

232

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

482

0.85

0.35

3.1

2.7

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

305

1.19

0.35

1.7

1.6

—

(3035350) Ketones [Presence] in Urine by Test strip

596

1.15

0.34

3.9

3.1

0.00

0.01

estimate

0.50

121

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.35

0.34

1.2

2.0

37.33

36.74

u/l

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.35

0.34

1.0

1.1

—

(3026493) Urate [Moles/volume] in Serum or Plasma

208

0.80

0.33

3.6

3.4

302.29

7142.32

umol/l

1.05

191

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.32

0.33

1.2

2.5

36.00

91.88

ng/l

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

1.29

0.32

1.5

1.2

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

1.28

0.30

1.1

1.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

167

1.23

0.30

1.4

1.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.34

0.29

4.3

5.2

—

(3009261) Glucose [Presence] in Urine by Test strip

603

1.13

0.28

3.6

3.2

0.00

estimate

-0.00

112

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

235

1.18

0.27

2.9

2.6

0.86

1.34

mg/l

0.49

160

(3018095) Leukocytes [#/volume] in Urine

399

1.14

0.27

5.0

4.2

12.97

40.55

e6/l

1.39

255

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

1.26

0.26

7.6

16.9

4.68

5.10

kpa

—

(3027801) Oxygen [Partial pressure] in Arterial blood

1.26

0.26

7.6

16.9

16.62

15.94

kpa

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

137

0.79

0.25

1.0

1.1

—

(3022621) pH of Urine by Test strip

1.18

0.25

1.7

1.9

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

1.26

0.23

3.9

3.3

20.64

21.22

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

172

1.19

0.23

2.4

3.6

8.10

3.29

e6/l

0.46

105

(3005033) Fetal Nuchal fold Thickness US

0.76

0.23

2.0

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.76

0.23

2.0

1.4

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.73

0.23

2.1

1.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

444

1.11

0.21

4.3

2.9

—

(40758558) Short blood count panel - Blood

298

1.13

0.21

9.0

8.3

—

(21494755) Public health laboratory ask at order entry panel

183

1.17

0.21

1.3

—

(3048689) Calprotectin [Mass/mass] in Stool

250

1.14

0.21

2.5

2.4

144.08

83.53

ug/g

0.34

190

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.2

—

(40768795) Lymph node Pathology biopsy report

0.00

0.21

0.0

1.5

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.21

0.0

1.3

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.3

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.3

—

(40761995) Spermatozoa Progressive [#/volume] in Semen

0.00

0.21

0.0

2.7

—

(3014043) Spermatozoa Nonprogressive/100 spermatozoa in Semen

0.00

0.21

0.0

5.4

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

1.8

—

(36304419) Bacteria [Presence] in Urine

290

1.13

0.20

3.0

3.7

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

574

1.10

0.20

2.4

2.2

—

(3000492) Spirometry study

122

0.81

0.20

1.2

1.3

—

(3019832) Treponema pallidum Ab [Presence] in Serum

392

0.90

0.19

2.3

1.8

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.25

0.19

1.1

1.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

816

0.92

0.19

6.5

4.0

—

(3000764) Benzodiazepines [Presence] in Urine

176

1.16

0.18

1.5

1.7

—

(36660697) Celiac disease serology panel - Serum

183

0.86

0.17

1.2

—

(3003694) ABO and Rh group [Type] in Blood

471

1.09

0.16

1.9

1.7

—

(40761536) Microorganisms panel - Urine sediment

121

1.17

0.15

2.7

3.6

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

122

1.16

0.14

1.4

1.3

—

(3027008) Opiates [Presence] in Urine

180

1.13

0.14

1.5

1.6

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

159

0.87

0.14

1.4

3.0

140.57

320.58

ng/l

—

(3028300) Cannabinoids [Presence] in Urine

181

1.12

0.13

1.5

1.6

—

(3020682) Albumin/Creatinine [Ratio] in Urine

181

1.12

0.13

5.2

4.0

5.03

18.17

mg/mmol

1.68

123

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.17

0.12

3.5

2.1

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

116

1.13

0.09

1.7

1.6

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

237

0.92

0.09

3.0

1.9

—

(40768797) Stomach Pathology biopsy report

113

0.88

0.08

2.0

1.2

—

(3016879) Cocaine [Presence] in Urine

164

0.91

0.08

1.5

1.7

—

(3026008) Bacteria identified in Urine by Culture

294

1.07

0.08

1.6

2.1

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

0.84

0.08

1.0

1.2

—

29.36

—

(3025941) Bacteria identified in Stool by Culture

1.10

0.07

2.0

1.2

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

1.03

0.07

1.8

2.3

—

16.90

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.83

0.07

1.3

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.83

0.07

1.4

1.5

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.88

0.07

1.6

1.7

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

110

1.10

0.05

1.7

1.4

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

110

1.10

0.05

1.7

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

110

1.10

0.05

1.7

1.4

—

(3027944) Amphetamines [Presence] in Urine

179

1.07

0.05

1.5

1.7

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

468

1.04

0.04

1.5

1.4

0.51

1.50

u/ml

1.93

(1001926) Buprenorphine [Presence] in Urine by Screen method

139

0.93

0.03

1.4

1.8

—

(3041096) Erythrocytes [Presence] in Urine by Automated

348

0.97

0.02

4.2

2.7

—

(3050129) First trimester maternal screen panel - Serum or Plasma

134

0.97

0.00

1.7

1.4

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.01

0.00

2.0

1.8

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

111

0.99

0.00

2.8

2.6

30.36

27.00

u/l

0.20

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

214

0.98

0.00

1.7

1.5

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

251

1.00

0.00

1.3

1.4

—

(3011288) Drugs identified in Urine by Screen method

123

0.97

0.00

1.6

2.1

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

127

1.03

0.00

1.8

1.5

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

183

0.98

0.00

1.3

0.99

8.66

u/ml

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

127

1267

1.01

0.00

3.6

3.8

—

(3012516) Albumin [Mass/volume] in Urine

178

1.01

0.00

4.3

3.5

32.61

105.92

mg/l

1.60

121

(3036603) Volume of Urine

0.00

0.0

2.4

—

1620.62

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.4

—

(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.1

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

1.94

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.0

1.6

—

774.88

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.89

0.00

1.2

1.6

—

(3025378) Microscopic observation [Identifier] in Cervix by Cyto stain

0.00

-0.00

0.0

1.1

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

110

1.00

-0.00

1.7

1.4

—

(3041365) Herpes simplex virus IgG Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

-0.00

0.0

2.4

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.6

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

87.67

—

(3023419) Bacteria identified in Sputum by Culture

0.00

-0.00

0.0

12.0

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

1556.86

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

6.19

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.5

—

(40758990) Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum

0.00

-0.00

0.0

1.3

—

8.37

—

(40761535) Cells panel - Urine sediment

0.89

-0.00

7.0

2.4

—

(3028707) Methadone [Presence] in Urine by Screen method

0.97

-0.00

1.4

2.1

—

(3040370) OLANZapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

181.86

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

15.9

—

14.56

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3020911) Cortisol [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.5

—

51.83

—

(3006462) Nitrate [Presence] in Urine

0.00

-0.00

0.0

1.5

—

(3001964) Herpes simplex virus Ag [Presence] in Specimen

0.00

-0.00

0.0

2.5

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(42868417) European tick borne encephalitis virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

0.94

-0.00

1.0

1.3

—

(42868647) JC virus Ab [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.2

—

(40759040) C peptide [Moles/volume] in Serum or Plasma --post meal

0.00

-0.00

0.0

1.0

—

1.11

—

(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative

0.00

-0.00

0.0

1.2

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

-0.00

0.0

1.7

—

(3008898) HLA-B27 [Presence]

0.97

-0.00

1.0

1.1

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3044927) Protein electrophoresis panel - Urine

0.00

-0.00

0.0

1.1

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.1

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

0.91

-0.00

2.1

1.7

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

0.84

—

(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum

0.00

-0.00

0.0

3.7

—

102.41

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.5

—

(3027300) Silver Birch IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

17.62

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint K11_SUPNUM_ONLY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_SUPNUM_ONLY.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: K11_SUPNUM_ONLY – Supernumerary teeth EXCLUDE clefts and syndromes

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Supernumerary teeth EXCLUDE clefts and syndromes

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints