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Congenital malformations of breast

Q17_CONGEN_MALFO_BREAST_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 Q83
  • Hospital discharge: ICD-10 Q83
  • Cause of death: ICD-10 Q83

3 out of 7 registries used, show all original rules.

732

4. Check minimum number of events

None

732

5. Include endpoints

None

732

6. Filter based on genotype QC (FinnGen only)

701

Control definitions (FinnGen only)

Control exclude
Q17_OTHER_CONGEN_MALFO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13
Parent code in ICD-10
Q8
Name in latin
Malformationes congenitae mammae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 701 690 11
Unadjusted period prevalence (%) 0.24 0.24 0.01
Median age at first event (years) 33.40 33.23 44.00

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
732
Matched controls
7320
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q83.8
ICD-10 Finland
Other congenital malformations of breast
+∞
307.7
362
*
Q83.1
ICD-10 Finland
Accessory breast
+∞
291.8
260
*
HAD40
NOMESCO Finland
Mastopexy
76.8
152.0
82
12
HAD99
NOMESCO Finland
Other plastic operation on breast
45.2
128.7
77
19
HAD10
NOMESCO Finland
Augmentation of breast using prosthesis
175.2
126.9
130
9
ZZF00
NOMESCO Finland
Graft of adipose tissue
31.1
117.1
78
28
HAC30
NOMESCO Finland
Excision of supernumerary mammary gland or mamilla
1088.1
99.5
95
*
Q83.9
ICD-10 Finland
Congenital malformation of breast, unspecified
+∞
85.1
80
*
HAE99
NOMESCO Finland
Other reconstruction of breast
24.8
71.2
51
22
Q83.3
ICD-10 Finland
Accessory nipple
+∞
56.0
53
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
5.2
54.6
128
289
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
5.9
45.8
89
169
N64.8
ICD-10 Finland
Other specified disorders of breast
17.4
45.6
38
23
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
40.4
33.8
42
11
ZXA10
NOMESCO Finland
Bilateral
3.2
33.5
164
613
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.7
32.8
82
193
N62
ICD-10 Finland
Hypertrophy of breast
4.6
32.1
81
192
N64.9
ICD-10 Finland
Disorder of breast, unspecified
8.9
29.9
38
45
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
29.0
282
1484
HAD00
NOMESCO Finland
Augmentation mammoplasty
107.8
28.9
31
*
T85.4
ICD-10 Finland
Mechanical complication of breast prosthesis and implant
100.6
26.8
29
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
26.1
202
949
HA1AA
NOMESCO Finland
X-ray mammography
3.7
24.7
86
257
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
4.9
21.1
48
104
QBJ00
NOMESCO Finland
Liposuction in trunk
21.5
20.1
29
14
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
19.5
280
1673
N64.2
ICD-10 Finland
Atrophy of breast
56.6
19.0
22
*
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
53.9
18.0
21
*
WX402
NOMESCO Finland
General anaesthesia
2.2
16.6
184
987
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
18.4
16.6
25
14
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
16.3
193
1061
N64.5
ICD-10 Finland
Other signs and symptoms in breast
4.0
15.6
46
122
Q83
ICD-10 Finland
Congenital malformations of breast
+∞
14.6
14
*
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
5.5
14.3
28
53
ZXA05
NOMESCO Finland
Left side
2.2
14.1
134
672
Q83.0
ICD-10 Finland
Congenital absence of breast with absent nipple
+∞
13.6
13
*
6114A
ICD-9 Finland
Other disorders of breast, Atrophy of breast
50.9
12.9
15
*
9729
FHL
Other measure in this category
28.5
10.8
14
5
QB2S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in chest
9.8
10.3
20
21
M03AX01
ATC
botulinum toxin; parenteral
4.1
10.1
28
71
HAB99
NOMESCO Finland
Other partial excision of mammary gland
4.4
10.1
25
58
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
20.4
9.8
14
7
N63
ICD-10 Finland
Unspecified lump in breast
2.3
9.5
79
373
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.1
9.4
39
130
ZXE00
NOMESCO Finland
One hour or less
1.6
9.4
294
2123
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
9.3
318
2343
N02BE01
ATC
paracetamol; systemic, rectal
2.0
9.3
638
5644
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
9.2
333
2488
ZXA00
NOMESCO Finland
Right side
1.9
9.0
128
738
R4110
NOMESCO Finland
Physiotherapy
1.8
9.0
169
1062
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.8
8.9
46
174
N64.4
ICD-10 Finland
Mastodynia
2.6
8.7
49
194
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
4.6
8.6
20
44
P01AB01
ATC
metronidazole; oral, rectal
1.6
8.4
319
2395
WX702
NOMESCO Finland
Supraglottic ventilation device
2.7
8.3
46
180
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
11.9
8.1
14
12
J01DB01
ATC
cefalexin; oral
1.8
8.0
615
5440
J02AC01
ATC
fluconazole; systemic
1.6
8.0
366
2858
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
6.0
7.7
20
34
S59
ICPC
Skin, Other therap proced/minor surg NEC
4.5
7.5
18
41
C05AA08
ATC
fluocortolone; rectal, topical
2.0
7.3
77
399
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
6.3
7.3
18
29
Z2221
NOMESCO Finland
Medical doctor
1.6
7.2
212
1488
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
7.1
288
2175
J01AA02
ATC
doxycycline; systemic
1.6
7.1
498
4227
X21
ICPC
Breast sympt/compl female other
2.9
7.0
32
113
C07AA05
ATC
propranolol; systemic
1.6
6.9
181
1233
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.0
6.9
77
408
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
3.6
6.8
22
63
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.7
294
2251
R00.2
ICD-10 Finland
Palpitations
2.0
6.5
69
358
ZXD20
NOMESCO Finland
Day surgery
1.9
6.5
89
506
F41.1
ICD-10 Finland
Generalized anxiety disorder
1.9
6.4
78
425
N05BA04
ATC
oxazepam; oral
1.6
6.3
187
1310
Q79.8
ICD-10 Finland
Other congenital malformations of musculoskeletal system
+∞
6.3
6
*
R51
ICD-10 Finland
Headache
2.0
6.2
67
350
QBJ99
NOMESCO Finland
Other aesthetic correction of skin of trunk
26.9
6.2
8
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
6.1
60
303
M01AE01
ATC
ibuprofen; systemic, rectal
2.2
6.1
687
6411
X22
ICPC
Concern breast appearance fema
12.7
6.1
10
8
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
6.1
194
1380
Z41.1
ICD-10 Finland
Other plastic surgery for unacceptable cosmetic appearance
8.7
6.1
12
14
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
6.0
250
1881

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
133
720
2.04
11.35
1.3
1.2
—
—
—
0
0
196
1244
1.79
10.19
2.7
3.1
100.88
98.12
%
1.02
191
1197
258
1855
1.60
8.08
3.5
4.1
37.29
37.16
g/l
0.14
238
1734
488
4077
1.59
7.85
6.1
5.8
70.02
71.48
u/l
0.45
459
3831
326
2506
1.54
7.48
2.1
1.9
—
—
—
0
0
252
1857
1.54
6.86
1.8
1.8
—
—
—
0
0
506
4327
1.55
6.78
3.8
3.5
8.64
9.00
mm/h
0.34
472
4045
631
5697
1.78
6.75
13.5
11.3
14.01
14.01
%
0.01
623
5597
374
3046
1.47
6.04
2.5
2.4
—
—
—
0
0
212
1550
1.52
5.82
2.5
2.3
56.56
55.68
u/l
0.11
194
1428
637
5836
1.71
5.57
9.4
8.7
3.87
3.88
mmol/l
0.67
621
5634
16
34
4.79
5.32
1.1
1.0
—
—
—
0
0
634
5821
1.67
5.25
9.4
8.7
139.42
139.49
mmol/l
0.39
620
5636
309
2475
1.43
5.20
2.4
2.2
73.50
73.55
nmol/l
0.01
282
2298
318
2566
1.42
5.11
4.6
4.6
9.38
9.38
umol/l
0.00
295
2389
666
6207
1.81
5.09
10.8
9.4
18.35
17.89
mg/l
0.14
519
4741
41
197
2.15
4.80
1.3
1.2
—
—
—
0
0
405
3436
1.40
4.75
2.7
2.6
—
—
—
0
0
724
7038
3.63
4.61
16.8
14.2
267.18
267.44
e9/l
0.04
712
6901
326
2682
1.39
4.52
5.9
5.2
0.68
0.66
%
0.26
301
2501
724
7045
3.53
4.48
16.8
14.2
6.70
6.76
e9/l
0.33
711
6893
580
5277
1.48
4.38
4.4
4.3
14.26
14.25
pmol/l
0.04
545
4931
337
2799
1.38
4.36
5.9
5.1
2.77
2.63
%
0.49
314
2628
339
2819
1.38
4.35
6.2
5.3
7.72
7.73
%
0.02
317
2655
724
7046
3.52
4.32
16.7
14.2
4.44
4.46
e12/l
0.72
711
6901
352
2951
1.37
4.27
5.9
5.1
30.98
29.96
%
1.29
330
2789
348
2915
1.37
4.23
5.7
4.9
55.16
56.32
%
1.31
325
2746
57
325
1.82
4.14
1.3
1.3
10.31
10.42
u/l
0.02
41
271
269
2185
1.37
3.88
4.9
5.0
1.22
1.22
mmol/l
0.15
230
1837
100
676
1.56
3.85
1.4
1.4
20.11
23.78
iu/l
0.63
81
578
487
4343
1.36
3.75
2.9
2.6
32.45
31.00
u/l
0.27
466
4159
20
79
2.57
3.66
2.4
2.0
—
—
—
0
0
137
1005
1.45
3.55
2.3
2.3
115.11
78.00
ug/g
0.94
106
770
237
1919
1.35
3.41
4.1
4.4
1.22
1.22
mmol/l
0.22
215
1753
347
2974
1.32
3.35
5.7
5.2
0.04
0.04
e9/l
0.01
302
2634
346
2967
1.32
3.32
5.7
5.1
0.52
0.52
e9/l
0.03
302
2633
228
1851
1.34
3.19
1.7
1.7
98.90
97.75
pmol/l
0.16
118
1006
358
3104
1.30
3.09
6.1
5.5
0.18
0.17
e9/l
0.45
317
2783
167
1304
1.36
3.00
3.4
3.3
7.40
7.40
ph
0.01
31
248
86
595
1.50
2.99
1.7
1.9
388.53
384.50
nmol/l
0.06
76
549
42
243
1.77
2.97
1.7
1.5
0.86
0.39
nmol/l
0.42
33
206
223
1822
1.32
2.95
2.0
2.2
—
—
—
0
0
672
6415
1.58
2.94
8.6
7.7
23.98
23.11
u/l
0.69
650
6218
39
223
1.79
2.87
2.0
2.0
20.97
20.64
s
0.27
33
183
356
3104
1.29
2.87
5.7
5.1
2.03
2.02
e9/l
0.03
319
2820
5
173
0.28
2.86
3.6
6.6
—
—
—
0
0
689
6625
1.68
2.82
10.4
8.9
—
—
—
0
0
416
3706
1.28
2.80
3.0
2.9
62.19
55.59
ug/l
0.87
393
3489
483
4388
1.30
2.78
4.4
3.8
—
—
—
0
0
95
682
1.45
2.76
1.2
1.1
—
—
—
0
0
19
86
2.24
2.65
3.4
2.2
—
—
—
0
0
384
3404
1.27
2.63
7.8
7.6
3.77
3.93
e9/l
0.98
338
2997
137
1058
1.36
2.62
2.3
2.3
9.20
10.68
e6/l
0.30
124
938
129
988
1.37
2.60
2.5
2.3
545.53
528.74
mosm/kgh2o
0.20
111
853
44
269
1.68
2.59
1.7
1.6
—
—
—
0
0
325
2827
1.27
2.59
6.2
5.4
—
—
—
0
0
184
1491
1.31
2.54
2.9
2.6
468.90
72.96
e6/l
0.44
144
1117
720
7035
2.43
2.54
16.6
14.1
39.54
39.66
%
0.27
701
6721
64
432
1.53
2.52
2.0
2.0
3.73
5.40
e9/l
1.28
54
388
170
1373
1.31
2.40
2.7
2.5
—
—
—
0
0
91
667
1.42
2.38
1.9
1.7
—
—
—
0
0
628
5966
1.37
2.32
5.1
4.9
1.63
1.91
mu/l
0.75
598
5673
205
1704
1.28
2.32
5.6
6.2
1.05
1.06
inr
0.17
74
614
309
2699
1.25
2.30
7.6
7.2
0.00
0.00
e9/l
1.53
247
2229
98
733
1.39
2.29
3.1
2.7
65.07
339.96
ng/l
1.20
44
351
167
1354
1.30
2.29
2.9
2.5
0.21
0.32
e6/l
0.40
129
999
465
4256
1.25
2.26
4.4
3.8
45.00
917.33
e6/l
—
6
45
336
2970
1.24
2.23
3.4
3.7
5.88
6.16
mmol/l
2.53
308
2621
14
61
2.32
2.15
1.2
1.3
—
—
—
0
0
166
1359
1.29
2.10
1.8
1.7
0.86
0.78
mg/l
0.25
127
991
23
124
1.88
2.09
1.0
1.1
—
—
—
0
0
193
1613
1.27
2.07
2.6
2.8
2.36
2.35
mmol/l
0.75
178
1466
294
2580
1.23
2.04
2.6
2.8
6.00
5.89
ph
0.32
35
261
43
280
1.57
2.02
1.1
1.1
—
—
—
0
0
96
731
1.36
2.02
1.9
2.3
2.42
2.41
mmol/l
0.50
83
631
93
706
1.36
2.00
2.6
2.2
2.02
5.02
e6/l
5.13
44
348
231
1979
1.24
1.99
3.4
2.9
78.27
52.93
e6/l
0.36
155
1232
69
501
1.42
1.93
1.3
1.3
—
—
—
0
0
170
1412
1.27
1.91
6.3
5.9
—
—
—
0
0
122
973
1.30
1.88
3.9
3.2
—
—
—
0
0
58
410
1.45
1.88
2.7
2.2
—
—
—
0
0
578
5475
1.26
1.84
3.4
3.2
5.53
5.53
mmol/l
0.04
532
5125
78
585
1.37
1.82
2.1
2.3
23.96
24.05
%
0.02
69
487
23
131
1.78
1.79
1.9
2.7
—
—
—
0
0
144
1182
1.27
1.78
1.3
1.3
2.25
10.29
u/ml
3.37
53
495
353
3190
1.21
1.76
4.3
4.2
0.01
0.00
estimate
0.42
78
681
514
4824
1.22
1.69
4.0
3.9
36.17
37.06
mmol/mol
2.05
487
4571
81
620
1.34
1.68
3.5
3.1
—
—
—
0
0
43
294
1.49
1.66
3.2
3.7
11.53
6.49
ug/l
0.36
29
216
225
1955
1.22
1.66
2.8
2.8
33.71
26.26
u/l
0.68
214
1863
36
237
1.55
1.65
1.0
1.1
0.66
4.21
u/ml
—
9
42
296
2643
1.20
1.65
2.2
2.1
—
—
—
0
0
8
32
2.52
1.60
1.8
2.1
43.11
45.62
%
—
8
32
14
70
2.02
1.60
1.1
1.3
—
—
—
0
0
354
3221
1.19
1.58
3.2
3.1
0.00
0.01
estimate
0.80
79
668
11
50
2.22
1.57
1.1
1.0
—
—
—
0
0
59
437
1.38
1.51
1.3
1.2
—
—
—
0
0
6
21
2.87
1.51
1.0
1.0
—
—
—
0
0
65
491
1.36
1.48
2.0
2.1
29.34
34.20
u/l
0.66
56
404
29
187
1.57
1.48
1.3
1.2
—
—
—
0
0
12
59
2.05
1.44
1.4
1.4
—
—
—
0
0
170
1457
1.22
1.43
2.1
2.0
2.41
2.63
mg/l
0.80
138
1241
131
1094
1.24
1.41
2.4
2.6
—
—
—
0
0
10
46
2.19
1.40
1.1
1.1
—
—
—
0
0
31
207
1.52
1.37
1.1
1.1
1.18
0.79
u/ml
0.32
14
89
6
23
2.62
1.37
2.0
2.9
0.26
0.16
e9/l
—
6
23
5
17
2.95
1.36
1.8
1.6
—
—
—
0
0
84
669
1.29
1.35
2.1
2.1
2.45
2.50
g/l
0.43
76
603
149
1270
1.22
1.33
1.4
1.5
—
—
—
0
0
17
98
1.75
1.32
1.4
1.6
—
—
—
0
0
67
519
1.32
1.32
2.8
3.6
4.49
4.62
pmol/l
0.60
60
463
19
114
1.68
1.29
3.1
3.1
22.73
25.97
mg/l
—
10
75
44
320
1.40
1.28
1.2
1.2
—
—
—
0
0
35
244
1.46
1.28
1.2
1.1
1.86
3.51
u/ml
0.69
20
128
143
1220
1.21
1.26
1.3
1.3
14.34
23.56
iu/ml
1.55
53
395
347
3195
1.16
1.25
3.1
3.1
0.00
0.00
estimate
0.50
81
699
15
85
1.78
1.23
3.5
2.3
3.29
2.42
mmol/l
—
10
55
50
375
1.36
1.22
1.3
1.3
—
—
—
0
0
123
1038
1.22
1.21
1.3
1.4
20.31
21.06
nmol/l
0.27
106
913
210
1863
1.18
1.21
1.4
1.3
1.01
1.98
u/ml
0.94
60
493
8
38
2.12
1.18
1.1
1.1
—
—
—
0
0
55
422
1.33
1.17
1.2
1.2
—
—
—
0
0
79
638
1.27
1.16
1.7
1.5
—
—
—
0
0
31
216
1.45
1.15
1.1
1.1
2.25
5.85
u/ml
1.52
17
114
91
749
1.25
1.14
2.1
2.1
15.13
14.75
umol/l
0.17
85
682
14
80
1.76
1.13
1.0
1.1
—
—
—
0
0
272
2477
1.16
1.11
1.9
1.9
—
—
—
0
0
158
1380
1.18
1.09
1.8
1.8
—
—
—
0
0
171
1504
1.18
1.09
2.2
2.6
14.18
19.61
ng/l
1.09
61
593
37
271
1.38
1.07
2.4
2.1
7.44
4.42
umol/l
0.53
30
204
85
700
1.24
1.07
1.5
1.4
—
—
—
0
0
13
75
1.75
1.03
1.2
1.1
0.20
2.89
u/ml
—
5
28
176
1563
1.17
1.00
1.5
1.4
2.08
2.03
g/l
0.20
108
972
9
50
1.81
0.97
1.4
1.5
275.57
462.44
pmol/l
—
9
43
0
32
0.00
0.95
0.0
1.7
—
—
—
0
0
35
260
1.36
0.95
5.3
6.6
—
—
—
0
0
156
1378
1.17
0.95
2.6
3.0
—
—
—
0
0
19
125
1.53
0.94
2.5
2.6
—
—
—
0
0
7
37
1.90
0.94
2.1
2.9
—
—
—
0
0
22
150
1.48
0.94
1.0
1.0
0.04
0.27
u/ml
—
8
44
6
27
2.23
0.93
1.2
1.5
176.50
168.51
mmol/24h
—
6
27
6
28
2.15
0.91
3.3
2.9
—
—
—
0
0
14
86
1.64
0.91
2.0
1.7
5021.89
12985.89
e6/l
—
9
66
50
395
1.29
0.90
2.7
3.1
—
—
—
0
0
20
135
1.50
0.90
1.3
1.3
2.22
5.95
u/ml
—
9
58
6
29
2.08
0.89
1.2
1.1
—
—
—
0
0
6
29
2.08
0.89
3.5
2.0
—
—
—
0
0
75
624
1.22
0.88
1.9
1.7
—
—
—
0
0
17
111
1.54
0.88
1.2
1.3
—
—
—
0
0
20
137
1.47
0.85
1.2
1.4
—
—
—
0
0
6
31
1.94
0.84
1.8
3.6
—
—
—
0
0
6
114
0.52
0.83
4.7
4.3
—
—
—
0
0
37
285
1.31
0.82
2.2
1.6
—
—
—
0
0
8
47
1.71
0.81
1.4
1.1
—
—
—
0
0
23
164
1.42
0.80
1.1
1.1
0.76
6.09
u/ml
3.16
11
69
28
207
1.37
0.80
2.0
2.1
—
—
—
0
0
60
496
1.23
0.77
1.3
1.7
—
—
—
0
0
6
34
1.77
0.76
2.7
1.3
15799.67
13361.46
e6/l
—
6
24
127
1125
1.16
0.76
1.9
2.2
5354.17
4169.53
umol/l
0.12
113
1019
11
67
1.65
0.75
1.5
1.3
—
—
—
0
0
13
83
1.58
0.75
1.2
1.0
0.53
1.49
u/ml
—
5
25
12
75
1.61
0.75
1.6
2.1
—
—
—
0
0
28
210
1.35
0.75
1.9
3.0
7.38
7.41
ph
—
5
26
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
7
39
1.80
0.72
1.0
1.1
1195.71
1621.28
miu/ml
—
7
39
64
537
1.21
0.72
1.3
1.7
—
—
—
0
0
11
68
1.63
0.72
2.2
2.0
—
—
—
0
0
5
26
1.93
0.70
1.0
1.2
6.36
6.24
nmol/l
—
5
26
7
41
1.71
0.70
1.0
1.0
—
—
—
0
0
64
539
1.21
0.70
1.3
1.7
—
—
—
0
0
9
58
1.56
0.70
1.0
1.1
—
—
—
0
0
28
213
1.33
0.69
1.2
1.1
0.51
2.28
u/ml
2.47
16
109
63
531
1.20
0.68
1.3
1.7
—
—
—
0
0
64
541
1.20
0.68
1.3
1.7
—
—
—
0
0
19
136
1.41
0.67
1.1
1.6
—
—
—
0
0
211
1949
1.12
0.67
3.0
2.7
—
—
—
0
0
27
349
0.76
0.66
2.0
3.1
—
—
—
0
0
24
180
1.34
0.65
1.1
1.1
0.58
5.58
u/ml
2.94
12
85
186
1708
1.12
0.65
3.3
3.3
0.00
0.00
estimate
1.08
78
675
69
591
1.18
0.64
2.2
2.1
6.42
4.97
umol/l
0.34
51
475
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
35
280
1.26
0.62
3.8
7.1
96.82
96.36
%
0.25
35
274
18
130
1.39
0.61
4.1
3.4
3.89
4.29
e9/l
0.43
18
130
146
1327
1.13
0.61
1.5
1.6
1.29
1.31
mmol/l
0.13
129
1171
51
427
1.21
0.61
1.3
1.7
—
—
—
0
0
14
197
0.71
0.59
1.6
2.2
13.46
5.10
ug/l
0.35
14
170
11
72
1.54
0.59
1.6
1.8
—
—
—
0
0
19
140
1.37
0.59
1.0
1.0
1.41
2.48
u/ml
—
10
76
149
1360
1.12
0.58
2.7
3.2
1.02
1.02
kg/l
0.14
22
200
86
758
1.15
0.57
1.2
1.2
96.27
156.27
iu/ml
1.31
30
317
18
132
1.37
0.57
4.6
3.8
56.61
56.89
%
0.04
18
132
125
1132
1.13
0.56
1.6
1.5
—
—
—
0
0
8
55
1.46
0.56
1.5
1.4
—
—
—
0
0
19
142
1.35
0.55
1.1
1.2
289.73
228.41
u/ml
0.48
11
89
66
573
1.17
0.54
1.4
1.3
—
—
—
0
0
9
61
1.48
0.54
1.2
1.7
—
—
—
0
0
77
678
1.15
0.53
1.7
1.6
1377.97
1148.18
nmol/l
0.51
68
518
29
232
1.26
0.53
3.0
2.1
62.90
71.98
e9/l
1.14
21
162
29
232
1.26
0.53
2.0
2.1
3.15
4.56
iu/l
0.70
15
97
6
40
1.50
0.51
1.2
1.3
5.08
5.76
ug/l
—
6
34
73
645
1.15
0.49
1.2
1.2
—
—
—
0
0
7
47
1.49
0.47
2.7
2.8
36514.29
40227.91
ug/l
—
7
47
26
209
1.25
0.47
1.2
1.1
—
—
—
0
0
7
48
1.46
0.47
1.3
1.4
94.81
92.31
%
—
7
48
7
49
1.43
0.46
2.4
1.8
61.71
60.51
%
—
7
49
15
112
1.35
0.45
5.1
3.1
1.42
1.27
mg/l
0.21
15
100
7
51
1.38
0.44
1.1
1.7
—
—
—
0
0
40
340
1.19
0.44
3.1
2.8
1.23
1.23
mmol/l
0.52
35
284
14
104
1.35
0.43
1.4
2.1
10.16
10.04
g/l
0.04
14
98
106
969
1.11
0.43
1.3
1.3
—
—
—
0
0
36
304
1.19
0.42
1.3
1.3
—
—
—
0
0
5
32
1.57
0.42
1.2
1.2
33.60
31.94
pg
—
5
32
51
582
0.87
0.42
1.4
1.4
—
—
—
0
0
8
60
1.34
0.40
2.3
3.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
8
61
1.31
0.39
1.1
1.2
—
—
—
0
0
5
36
1.39
0.38
1.8
2.7
—
—
—
0
0
63
564
1.13
0.37
1.5
1.3
—
—
—
0
0
549
5386
1.08
0.37
3.0
3.0
1.13
1.16
mmol/l
0.54
522
5123
22
180
1.23
0.36
1.4
2.1
—
—
—
0
0
12
90
1.34
0.36
1.0
2.0
42.61
39.15
g/l
2.15
12
85
61
548
1.12
0.35
1.5
1.4
—
—
—
0
0
139
1303
1.08
0.34
2.2
3.0
7.83
7.87
mmol/l
0.04
126
1141
42
368
1.15
0.34
1.1
1.1
—
—
—
0
0
229
2188
1.07
0.34
1.8
1.8
—
—
—
0
0
6
45
1.34
0.34
1.2
1.3
62.50
67.91
umol/l
—
6
45
14
109
1.29
0.33
1.1
1.1
—
—
—
0
0
103
955
1.09
0.33
1.4
1.4
728.42
563.69
titre
0.25
19
195
6
89
0.67
0.33
2.3
5.9
294.00
380.45
umol/l
—
6
76
35
304
1.16
0.32
2.5
2.9
1.90
1.83
mmol/l
0.03
30
242
62
561
1.11
0.32
1.6
1.5
—
—
—
0
0
21
174
1.21
0.31
3.1
4.9
—
—
—
0
0
7
52
1.35
0.31
1.0
1.2
—
—
—
0
0
35
306
1.15
0.30
2.5
2.9
5.98
5.79
kpa
0.36
35
299
7
55
1.28
0.30
1.7
1.6
5.11
5.17
mmol/l
—
7
55
206
1971
1.06
0.29
1.9
1.7
—
—
—
0
0
60
545
1.11
0.29
1.5
1.4
—
—
—
0
0
7
56
1.25
0.29
1.0
1.7
—
—
—
0
0
18
148
1.22
0.29
1.3
1.4
324.13
320.93
ug/g
—
8
81
15
121
1.24
0.28
1.1
1.2
—
—
—
0
0
43
388
1.12
0.25
1.5
2.2
—
—
—
0
0
105
989
1.07
0.25
1.5
1.5
437.01
47446512.64
pmol/l
1.82
93
881
579
5719
1.06
0.24
3.6
3.5
2.88
2.85
mmol/l
0.32
552
5430
23
200
1.15
0.22
1.1
1.3
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
19
163
1.17
0.21
4.1
7.9
—
—
—
0
0
5
42
1.19
0.21
1.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
29
258
1.13
0.21
2.0
2.4
4.77
4.66
kpa
0.12
29
253
11
89
1.24
0.21
1.2
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
32
289
1.11
0.19
2.3
3.7
67.33
70.94
ng/l
0.17
27
263
13
154
0.84
0.19
2.5
2.7
25.26
24.84
mmol/l
0.18
13
149
7
58
1.21
0.18
1.0
1.3
—
—
—
0
0
13
153
0.85
0.18
1.5
3.0
0.21
0.31
g/l
—
5
57
7
60
1.17
0.18
1.6
1.6
—
—
—
0
0
36
392
0.91
0.17
3.4
5.4
105.94
104.83
mmol/l
1.21
36
392
21
187
1.13
0.16
1.7
1.5
—
—
—
0
0
6
76
0.79
0.15
1.2
1.3
—
—
—
0
0
105
1007
1.05
0.15
3.1
3.9
8.46
9.94
mg/mmol
0.13
64
641
8
98
0.81
0.13
1.6
2.0
432.88
148.14
ug/l
—
8
84
569
5644
1.04
0.13
3.3
3.2
1.58
1.54
mmol/l
1.22
542
5379
65
618
1.06
0.13
1.4
1.3
—
—
—
0
0
11
94
1.17
0.13
2.9
1.8
6.42
5.16
mmol/24h
0.51
11
82
36
386
0.93
0.13
4.7
4.2
0.00
0.12
%
—
6
81
19
171
1.11
0.12
4.2
1.9
—
—
—
0
0
16
143
1.12
0.11
1.4
1.1
—
—
—
0
0
35
328
1.07
0.11
5.5
6.7
5.16
5.07
kpa
0.13
35
313
35
328
1.07
0.11
5.5
6.6
13.33
13.37
kpa
0.01
35
314
14
125
1.12
0.10
2.7
4.8
1.52
1.64
%
0.26
14
119
37
391
0.94
0.09
4.3
3.9
0.38
0.76
%
—
8
98
6
57
1.05
0.08
3.3
2.1
—
—
—
0
0
13
144
0.90
0.08
1.1
1.3
3.56
3.64
mmol/l
0.17
13
132
5
61
0.82
0.08
3.0
2.0
10.46
10.87
u/ml
—
5
61
28
297
0.94
0.08
6.1
5.2
1.27
1.20
mmol/l
0.20
28
287
103
1056
0.97
0.08
2.3
2.1
—
—
—
0
0
40
419
0.95
0.08
4.5
4.1
0.80
0.96
%
—
10
114
92
896
1.03
0.07
2.1
2.2
5893.88
6156.89
u/l
0.03
40
379
11
98
1.12
0.07
1.3
2.6
1.02
0.88
nmol/l
0.35
11
83
23
215
1.07
0.07
1.7
1.8
—
—
—
0
0
9
87
1.03
0.07
2.7
1.6
—
—
—
0
0
569
5664
1.02
0.06
3.4
3.3
4.81
4.77
mmol/l
0.43
546
5418
20
188
1.07
0.05
3.9
6.4
24.29
24.58
mmol/l
0.16
20
180
15
139
1.08
0.05
1.7
3.4
—
—
—
0
0
15
140
1.07
0.04
4.7
8.1
24.27
24.24
mmol/l
0.01
15
134
15
140
1.07
0.04
1.1
1.2
—
—
—
0
0
240
2420
0.99
0.04
2.2
2.2
—
—
—
0
0
34
329
1.04
0.03
5.6
6.6
1.19
1.25
mmol/l
0.02
26
254
39
401
0.97
0.03
4.4
4.2
0.38
0.08
%
—
8
95
18
171
1.05
0.03
1.4
1.1
—
—
—
0
0
18
171
1.05
0.03
1.4
1.1
—
—
—
0
0
48
470
1.02
0.02
2.2
2.3
10.09
21.18
au/ml
—
8
45
25
242
1.03
0.02
1.4
2.0
—
—
—
0
0
10
93
1.08
0.02
1.4
1.4
—
67.02
—
0
6
12
127
0.94
0.01
1.1
1.4
29.34
31.94
nmol/l
0.13
12
113
48
473
1.02
0.01
1.3
1.3
235.63
249.99
miu/ml
0.12
25
249
25
244
1.03
0.00
3.2
2.2
—
—
—
0
0
97
964
1.01
0.00
2.6
3.3
635.58
401.10
mg/l
0.16
63
633
10
104
0.96
0.00
1.0
1.1
—
—
—
0
0
18
184
0.98
0.00
1.4
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
2.50
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
1.44
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
1.34
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
71.13
—
0
6
0
8
0.00
-0.00
0.0
1.1
—
18.01
—
0
8
0
9
0.00
-0.00
0.0
3.6
—
24.99
—
0
9
0
8
0.00
-0.00
0.0
1.9
—
49.63
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
225.00
—
0
5
0
6
0.00
-0.00
0.0
8.0
—
—
—
0
0
8
88
0.91
-0.00
3.1
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
104.40
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
14.24
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
34.48
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
35.06
—
0
5
6
64
0.94
-0.00
1.2
1.7
—
—
—
0
0
5
52
0.96
-0.00
1.6
1.8
0.92
0.97
g/l
—
5
52
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_CONGEN_MALFO_BREAST_WIDE – Congenital malformations of breast

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).