Sleepwalking [somnambulism]

F5_SLEEPWALKING

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F51.3
  • Cause of death: ICD-10 F51.3

2 out of 7 registries used, show all original rules.

98

4. Check minimum number of events

None

98

5. Include endpoints

None

98

6. Filter based on genotype QC (FinnGen only)

98

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 741 345 395
Only index persons 706 334 372
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 24.02 29.30 19.39
Only index persons 24.31 29.66 19.51

-FinnGen-

Key figures

All Female Male
Number of individuals 98 69 29
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 34.44 37.36 27.49

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
84
Matched controls
838
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F51.3
ICD-10 Finland
Sleepwalking [somnambulism]
+∞
120.9
84
*
G47.9
ICD-10 Finland
Sleep disorder, unspecified
40.2
15.6
19
6
F51.9
ICD-10 Finland
Nonorganic sleep disorder, unspecified
34.5
9.7
12
*
IAB13
NOMESCO Finland
Psychiatric sleep disorder consultation
+∞
9.5
9
*
N03AE01
ATC
clonazepam; systemic
11.7
7.9
14
14
N06AX11
ATC
mirtazapine; oral
3.6
6.5
36
143
F51.4
ICD-10 Finland
Sleep terrors [night terrors]
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
42
239
2.33
3.93
4.4
5.9
—
—
—
0
0
42
245
2.25
3.66
1.7
1.8
103.0
97.3
pmol/l
0.31
22
130
19
81
2.67
3.23
1.4
1.2
—
—
—
0
0
10
29
3.73
3.14
1.0
1.2
—
—
—
0
0
42
259
2.09
3.07
3.7
3.1
23.0
47.0
e6/l
0.49
30
175
13
46
3.11
3.05
1.3
1.2
—
—
—
0
0
36
214
2.08
2.87
3.3
2.5
11.2
75.7
e6/l
1.42
28
163
47
311
1.98
2.77
1.7
1.9
—
—
—
0
0
6
10
6.31
2.74
1.2
1.4
—
—
—
0
0
32
187
2.06
2.64
7.1
6.4
—
—
—
0
0
65
491
1.96
2.51
4.7
4.1
—
39.5
—
0
6
50
349
1.88
2.43
6.7
7.9
0.0
0.0
e9/l
0.00
42
289
37
234
1.93
2.42
1.5
1.3
1.3
1.2
u/ml
0.07
12
57
15
66
2.50
2.38
2.8
1.8
319.4
4893.0
u/l
—
7
19
10
35
3.07
2.38
21.9
10.0
—
—
—
0
0
32
197
1.93
2.25
3.4
2.5
0.3
0.1
e6/l
0.51
24
143
55
404
1.82
2.21
6.3
6.1
0.2
0.2
e9/l
0.06
50
367
53
389
1.79
2.10
6.3
5.7
0.0
0.0
e9/l
0.04
48
351
53
389
1.79
2.10
6.3
5.7
0.5
0.5
e9/l
1.27
48
351
81
683
2.07
2.00
4.0
3.4
5.8
5.6
mmol/l
0.74
74
639
32
204
1.84
2.00
3.5
2.4
—
—
—
0
0
44
310
1.76
1.97
3.6
2.7
—
—
—
0
0
67
535
1.80
1.92
3.8
4.1
—
—
—
0
0
10
40
2.67
1.90
5.0
2.7
—
—
—
0
0
31
199
1.82
1.88
2.1
2.8
11.8
67.7
ng/l
0.97
16
99
17
89
2.10
1.84
1.3
1.2
—
—
—
0
0
32
209
1.79
1.83
1.4
1.3
2.2
2.1
g/l
0.01
18
118
51
381
1.71
1.82
5.2
4.5
0.0
0.0
estimate
0.00
12
80
26
160
1.85
1.80
1.5
2.0
0.6
0.7
mg/l
0.26
18
114
93
850
2.84
1.79
10.4
9.5
—
—
—
0
0
13
62
2.26
1.75
2.0
1.8
—
—
—
0
0
8
31
2.72
1.70
1.4
7.5
4.9
7.1
mmol/l
—
8
31
6
19
3.29
1.69
1.3
1.2
0.3
2.2
e6/l
—
6
14
6
19
3.29
1.69
1.3
1.7
0.6
0.6
%
—
6
19
51
388
1.66
1.65
4.2
3.1
0.0
0.0
estimate
0.00
12
75
15
79
2.06
1.60
1.7
2.8
3.3
4.8
umol/l
1.04
15
66
15
80
2.03
1.55
1.1
1.5
—
—
—
0
0
5
15
3.45
1.54
1.2
1.7
—
—
—
0
0
5
15
3.45
1.54
1.4
1.3
—
—
—
0
0
6
21
2.97
1.53
1.3
1.9
0.9
1.4
%
—
6
21
7
28
2.61
1.48
1.3
1.2
—
—
—
0
0
89
808
2.10
1.48
13.7
10.5
19.2
21.9
mg/l
0.31
71
611
55
437
1.59
1.42
3.0
3.0
—
—
—
0
0
29
198
1.66
1.39
1.9
6.1
1.0
1.1
inr
2.55
13
72
56
454
1.54
1.28
9.6
8.0
3.6
4.1
e9/l
1.92
51
402
49
386
1.54
1.27
4.2
3.0
0.0
0.0
estimate
0.00
12
77
24
160
1.66
1.25
4.5
3.0
—
—
—
0
0
21
135
1.71
1.24
3.6
3.4
9.4
124.0
mg/l
1.26
15
87
23
152
1.67
1.23
4.2
4.3
—
—
—
0
0
22
144
1.68
1.22
1.8
2.7
288.1
3057.4
umol/l
0.50
17
130
81
721
1.71
1.18
14.4
12.5
13.3
13.3
%
0.18
81
713
14
82
1.83
1.12
1.3
1.6
—
—
—
0
0
7
33
2.21
1.08
1.3
2.1
40.1
126.8
ng/l
—
7
28
15
92
1.74
1.04
1.3
1.2
—
—
—
0
0
40
315
1.46
0.99
2.2
2.2
—
—
—
0
0
27
197
1.51
0.96
5.3
2.9
0.0
0.0
estimate
0.00
12
78
12
72
1.76
0.90
2.4
1.4
—
—
—
0
0
8
46
1.80
0.85
1.5
1.7
0.0
2.6
mmol/l
—
8
31
7
121
0.55
0.85
1.0
1.3
—
—
—
0
0
6
32
1.93
0.83
1.3
1.6
—
—
—
0
0
8
48
1.72
0.81
1.1
1.1
—
—
—
0
0
8
48
1.72
0.81
1.5
2.3
—
—
—
0
0
20
142
1.51
0.80
3.9
4.0
1.0
15.3
mg/mmol
1.35
14
94
12
75
1.68
0.79
1.3
2.1
373.7
399.1
nmol/l
0.25
12
70
5
24
2.14
0.75
41.6
14.3
0.7
0.7
%
—
5
24
5
24
2.14
0.75
41.6
14.3
1.5
1.5
%
—
5
24
5
25
2.05
0.74
1.4
1.4
23.8
24.6
mmol/l
—
5
25
7
41
1.76
0.71
1.0
1.1
—
—
—
0
0
20
146
1.46
0.71
2.4
3.3
—
—
—
0
0
18
129
1.48
0.70
1.3
1.3
52.6
7.1
u/ml
—
6
63
81
749
1.47
0.69
4.0
3.5
2.7
2.8
mmol/l
0.65
75
708
84
785
1.49
0.64
16.3
11.4
40.5
40.6
%
0.09
70
656
8
50
1.65
0.63
1.3
1.2
—
—
—
0
0
8
51
1.62
0.62
1.6
2.2
—
—
—
0
0
11
72
1.59
0.62
2.5
5.5
1.0
1.0
mmol/l
0.07
11
65
0
22
0.00
0.60
0.0
1.1
—
—
—
0
0
77
714
1.37
0.57
3.2
3.1
1.1
1.2
mmol/l
1.43
72
674
23
287
0.74
0.56
1.8
1.7
—
—
—
0
0
12
83
1.51
0.55
1.1
1.4
—
—
—
0
0
6
39
1.57
0.54
1.5
1.6
—
—
—
0
0
26
211
1.32
0.51
2.4
2.4
—
—
—
0
0
12
85
1.47
0.49
1.5
1.7
1151.7
1067.5
nmol/l
0.14
12
63
79
741
1.34
0.49
3.6
3.3
1.5
1.5
mmol/l
0.10
74
700
15
112
1.40
0.48
2.0
3.5
8.5
32.0
ng/l
—
10
60
12
86
1.45
0.47
1.1
1.2
—
—
—
0
0
13
95
1.42
0.46
2.1
3.7
0.8
0.8
mmol/l
0.05
13
90
24
196
1.30
0.45
5.5
4.5
—
—
—
0
0
8
55
1.49
0.44
1.9
1.8
—
—
—
0
0
8
59
1.39
0.42
4.8
3.5
—
0.1
—
0
11
79
746
1.30
0.42
3.7
3.3
4.5
4.7
mmol/l
0.83
74
708
0
17
0.00
0.41
0.0
4.1
—
3.9
—
0
17
0
17
0.00
0.41
0.0
4.1
—
52.1
—
0
17
0
18
0.00
0.40
0.0
4.3
—
22.3
—
0
10
12
89
1.40
0.40
3.3
2.6
—
—
—
0
0
9
68
1.36
0.39
4.4
2.7
—
—
—
0
0
9
68
1.36
0.39
1.3
1.4
—
—
—
0
0
6
41
1.49
0.37
2.2
1.3
—
—
—
0
0
11
83
1.37
0.33
1.3
1.4
—
—
—
0
0
11
83
1.37
0.33
1.3
1.4
—
—
—
0
0
11
84
1.35
0.31
1.3
1.4
—
—
—
0
0
26
224
1.22
0.31
2.3
2.2
—
—
—
0
0
10
79
1.30
0.23
1.3
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
5.0
—
0
11
0
11
0.00
0.21
0.0
3.5
—
9.5
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.8
—
17.6
—
0
10
0
12
0.00
0.21
0.0
2.5
—
16.6
—
0
5
0
12
0.00
0.21
0.0
2.3
—
6.5
—
0
12
0
12
0.00
0.21
0.0
2.3
—
1.3
—
0
12
7
60
1.18
0.18
1.3
1.2
—
—
—
0
0
10
84
1.21
0.14
1.3
1.4
—
—
—
0
0
19
172
1.13
0.12
1.4
1.5
—
—
—
0
0
76
741
1.11
0.12
18.4
12.7
332.0
333.7
g/l
0.93
76
736
26
241
1.11
0.12
3.5
2.6
—
—
—
0
0
5
47
1.07
0.09
1.2
5.2
—
—
—
0
0
12
107
1.14
0.09
2.3
2.0
—
—
—
0
0
17
156
1.11
0.08
1.4
1.6
—
—
—
0
0
6
58
1.04
0.08
4.3
1.4
271.8
252.2
mu/l
—
6
52
23
220
1.06
0.04
1.7
1.8
—
—
—
0
0
11
104
1.06
0.01
1.4
1.4
—
—
—
0
0
26
254
1.03
0.00
1.5
1.7
—
—
—
0
0
31
313
0.99
0.00
1.9
2.3
—
—
—
0
0
0
8
0.00
0.00
0.0
2.3
—
57.9
—
0
8
0
8
0.00
0.00
0.0
7.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
3.9
—
0
8
0
8
0.00
0.00
0.0
2.4
—
106.4
—
0
8
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
2.9
—
89.1
—
0
8
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
0.00
0.0
2.8
—
1.8
—
0
9
0
5
0.00
0.00
0.0
1.4
—
0.1
—
0
5
0
7
0.00
0.00
0.0
1.3
—
10.9
—
0
7
0
5
0.00
0.00
0.0
1.0
—
7.8
—
0
5
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
83.0
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
6
60
1.00
0.00
6.3
3.6
—
0.0
—
0
13
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
32.3
—
0
7
5
57
0.87
0.00
1.6
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint F5_SLEEPWALKING and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have F5_SLEEPWALKING.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: F5_SLEEPWALKING – Sleepwalking [somnambulism]

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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