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Acrodermatitis continua

DOID EFO Endpoint Browser PheWeb

L12_PSORI_ACRODERM

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L40.2
  • Hospital discharge: ICD-9 — 6961C
  • Hospital discharge: ICD-8 — 68696
  • Cause of death: ICD-10 — L40.2
  • Cause of death: ICD-9 — 6961C
  • Cause of death: ICD-8 — 68696

2 out of 7 registries used, show all original rules.

70

4. Check minimum number of events

None

70

5. Include endpoints

None

70

6. Filter based on genotype QC (FinnGen only)

70

Control definitions (FinnGen only)

Control exclude
L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L40
Name in latin
Acrodermatitis continua (Hallopeau)

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 449 266 181
Only index persons 419 250 169
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 55.60 54.91 56.85
Only index persons 55.27 54.78 55.99

-FinnGen-

Key figures

All Female Male
Number of individuals 70 45 25
Unadjusted period prevalence (%) 0.01 0.02 0.01
Median age at first event (years) 55.42 52.55 60.59

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
65
Matched controls
648
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L40.2
ICD-10 Finland
Acrodermatitis continua
+∞
88.0
63
*
D05BB02
ATC
acitretin; oral
396.4
26.8
25
*
D07AD01
ATC
clobetasol; topical
23.4
26.6
44
53
D05AX52
ATC
calcipotriol, combinations; topical
40.5
25.5
32
15
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
27.7
24.5
35
26
L40.0
ICD-10 Finland
Psoriasis vulgaris
173.8
23.3
23
*
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
+∞
16.3
15
*
D07XC01
ATC
betamethasone, combinations; topical
14.0
15.8
29
35
E0000UV
ATC
NA
9.3
15.2
49
160
D05AX02
ATC
calcipotriol; topical
40.5
14.8
18
6
L40.5
ICD-10 Finland
Arthropathic psoriasis
95.6
14.2
15
*
319
Kela drug reimbursment
Adalimumab, brodalumab, certolizumab pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, sekukinumab and ustekinumab (skin psoriasis)
+∞
11.8
11
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
7.5
10.8
29
63
E000001
ATC
NA
6.7
10.6
32
82
D07AC01
ATC
betamethasone; topical
5.8
10.2
40
140
L04AB04
ATC
adalimumab; parenteral
116.2
9.7
10
*
L40.8
ICD-10 Finland
Other psoriasis
+∞
9.6
9
*
S91
ICPC
Psoriasis
+∞
9.6
9
*
M07.3
ICD-10 Finland
Other psoriatic arthropathies
+∞
9.6
9
*
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
43.3
9.3
11
*
D05AX03
ATC
calcitriol; topical
102.8
8.6
9
*
L40.9
ICD-10 Finland
Psoriasis, unspecified
38.7
8.3
10
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
11.8
8.3
15
16
E000003
ATC
NA
15.9
8.3
13
10
L30.3
ICD-10 Finland
Infective dermatitis
18.5
7.5
11
7
D07AC13
ATC
mometasone; topical
4.4
7.3
33
123
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
10.5
6.9
13
15
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
6.4
6.5
17
34

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(42870588) Differential panel, method unspecified - Blood
42
189
4.06
7.69
16.1
4.8
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
19
50
4.84
7.10
5.1
4.6
%
0.3
0.5
—
9
15
(3002179) Metamyelocytes/100 leukocytes in Blood
17
42
5.03
6.81
4.8
4.4
%
0.0
0.5
—
7
8
(3000494) Fungus identified in Specimen by Culture
22
71
4.06
6.28
2.2
1.3
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
17
45
4.67
6.25
5.3
4.8
%
0.0
0.1
—
8
13
(3021879) Hepatitis B virus core Ab [Presence] in Serum
16
42
4.64
5.93
1.5
1.4
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
30
129
3.32
5.50
10.8
5.4
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
16
45
4.31
5.42
5.2
4.8
%
0.0
0.0
—
7
12
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
8
6
14.80
5.21
1.3
1.0
—
—
—
0
0
(40768443) Skin Pathology biopsy report
10
19
5.97
5.21
1.4
1.1
—
—
—
0
0
(3023420) DNA double strand Ab [Units/volume] in Serum
7
6
12.76
4.37
1.1
1.2
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
7
8
9.55
3.86
1.3
1.4
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
9
17
5.90
3.64
1.8
2.1
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
19
79
2.93
3.51
2.2
1.8
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
9
18
5.57
3.50
1.8
2.3
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
15
61
2.86
2.85
2.1
1.5
—
—
—
0
0
(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method
5
6
8.84
2.79
1.4
1.2
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
17
75
2.67
2.78
1.5
1.5
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
53
389
2.49
2.75
6.8
4.1
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
58
456
2.59
2.38
14.0
7.4
u/l
78.0
75.5
0.31
58
429
(3030905) Polymorphonuclear cells [#/volume] in Blood
6
14
4.58
2.20
2.0
2.6
e9/l
3.7
5.6
—
6
14
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
6
14
4.58
2.20
2.0
2.6
%
52.7
63.9
—
6
14
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
31
197
2.03
2.14
4.5
3.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
8
26
3.34
2.08
1.8
1.7
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
5
11
4.80
1.97
1.2
1.5
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
24
143
2.03
1.94
2.2
2.9
mmol/l
7.3
7.9
0.28
16
116
(3031040) Bacteria [#/volume] in Urine by Automated count
49
377
2.00
1.86
7.6
4.1
—
73.8
—
0
12
(46235355) HIV 1 and 2 tests - Meaningful Use set
21
121
2.05
1.85
1.8
1.8
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
18
100
2.08
1.73
1.6
1.7
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
42
313
1.85
1.69
7.3
6.2
umol/l
12.1
10.8
0.26
42
301
(3013707) Erythrocyte sedimentation rate by Westergren method
54
437
2.03
1.68
10.0
4.0
mm/h
14.5
10.9
1.32
54
402
(3002582) Erythrocytes [#/volume] in Urine
27
178
1.84
1.59
4.0
3.3
e6/l
14.5
384.8
0.54
21
142
(3023368) Bacteria identified in Blood by Culture
23
144
1.89
1.58
5.5
4.2
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
30
205
1.81
1.57
6.3
3.9
e6/l
19.5
88.8
1.57
21
149
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
39
0.00
1.39
0.0
1.5
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
26
177
1.75
1.35
3.2
2.2
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
21
134
1.81
1.35
2.4
3.1
mg/l
33.8
559.6
—
10
82
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
14
78
1.99
1.33
3.3
3.2
e6/l
1.1
0.9
—
7
45
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
15
86
1.95
1.32
4.7
2.7
ng/l
22.0
49.6
—
10
61
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
5
19
2.75
1.23
2.0
2.5
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
5
19
2.75
1.23
1.0
1.3
—
—
—
0
0
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
5
19
2.75
1.23
1.8
1.6
—
340.7
—
0
10
(3004588) Protein electrophoresis panel - Serum or Plasma
8
38
2.24
1.23
1.5
1.5
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
37
284
1.64
1.20
5.1
3.7
estimate
0.0
0.0
—
8
53
(3020682) Albumin/Creatinine [Ratio] in Urine
21
139
1.73
1.18
3.5
4.0
mg/mmol
5.6
8.5
0.34
11
80
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
8
41
2.07
1.13
2.1
1.4
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
9
45
2.14
1.10
1.4
1.7
g/l
67.4
66.0
—
9
40
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
19
125
1.71
1.09
3.9
2.2
—
—
—
0
0
(3019225) pH of Specimen
9
46
2.10
1.09
5.1
4.1
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
18
117
1.72
1.07
1.4
1.7
mg/l
0.8
1.0
0.28
12
89
(3018418) pH of Serum or Plasma
25
178
1.63
1.07
2.3
3.9
ph
7.4
7.4
—
6
36
(3030467) Casts [#/volume] in Urine by Automated count
22
152
1.65
1.05
4.5
3.2
e6/l
0.4
0.4
0.02
17
116
(40761536) Microorganisms panel - Urine sediment
9
48
2.00
1.05
2.9
3.4
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
29
215
1.60
1.05
13.6
7.6
inr
1.7
1.1
—
9
66
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
36
282
1.57
1.03
6.1
5.6
mmol/l
1.2
1.2
0.02
27
242
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
31
235
1.57
1.02
2.7
2.3
nmol/l
82.0
77.8
0.33
26
212
(36304419) Bacteria [Presence] in Urine
22
156
1.60
0.94
4.3
2.9
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
10
56
1.92
0.93
2.4
1.4
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
10
57
1.88
0.89
2.5
1.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
12
74
1.75
0.85
2.1
1.7
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
32
1.95
0.84
6.5
5.6
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
0
25
0.00
0.81
0.0
1.1
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
25
0.00
0.81
0.0
1.3
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
64
592
1.94
0.80
25.4
12.7
mg/l
18.5
22.2
0.54
58
458
(3009261) Glucose [Presence] in Urine by Test strip
35
287
1.44
0.74
4.3
3.8
estimate
0.0
0.0
—
7
52
(40761535) Cells panel - Urine sediment
7
41
1.78
0.72
4.3
2.9
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
12
78
1.65
0.71
3.4
3.5
e6/l
3.5
4.7
—
5
45
(40768804) Tissue Pathology biopsy report
29
232
1.43
0.69
1.8
2.1
—
—
—
0
0
(4010399)
7
44
1.66
0.67
1.1
1.3
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
19
142
1.46
0.63
2.0
3.0
ng/l
2954.9
1079.1
0.37
14
122
(3021601) Nitrite [Presence] in Urine by Test strip
34
284
1.38
0.62
6.3
5.2
estimate
0.0
0.0
—
8
54
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
20
0.00
0.61
0.0
1.3
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
22
0.00
0.60
0.0
1.5
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
15
108
1.49
0.59
1.3
1.3
u/ml
47.0
16.5
—
6
44
(3050129) First trimester maternal screen panel - Serum or Plasma
0
23
0.00
0.59
0.0
1.4
—
—
—
0
0
(40758558) Short blood count panel - Blood
20
153
1.43
0.59
14.4
7.1
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
25
204
1.35
0.50
3.4
3.4
ng/l
16.7
33.3
0.83
16
137
(1761868) Lipid panel - Serum or Plasma
18
225
0.73
0.48
3.2
2.6
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
21
171
1.33
0.42
3.9
2.8
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
5
33
1.55
0.42
1.8
2.7
ug/l
2.2
6.4
—
5
28
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
5
34
1.51
0.41
2.2
4.0
e6/l
0.2
0.1
—
5
34
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
8
113
0.67
0.41
1.5
1.4
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
(3019060) Gas panel - Arterial blood
5
36
1.42
0.39
7.4
3.8
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
5
36
1.42
0.39
1.8
1.8
g/l
0.8
1.3
—
5
31
(3000991) Gas panel - Venous blood
6
41
1.51
0.37
3.0
6.1
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
15
120
1.32
0.33
1.5
1.3
g/l
3.7
2.3
—
8
71
(40768797) Stomach Pathology biopsy report
11
85
1.35
0.30
1.2
1.4
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
59
615
0.74
0.30
22.6
12.1
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
16
133
1.26
0.27
5.1
3.1
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
57
542
1.28
0.27
20.3
12.5
ml/min/173m2
89.3
83.9
1.36
51
438
(3002385) Erythrocyte distribution width [Ratio]
47
500
0.82
0.27
31.1
16.2
%
14.2
13.7
1.01
47
492
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
30
270
1.19
0.25
5.0
3.8
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
13
156
0.80
0.24
1.4
1.6
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
5
40
1.27
0.23
3.2
2.5
—
—
—
0
0
(3038515) Glucose [Moles/volume] in Venous blood
0
11
0.00
0.21
0.0
1.5
—
7.0
—
0
11
(3008037) Lactate [Moles/volume] in Venous blood
0
11
0.00
0.21
0.0
1.9
—
1.6
—
0
11
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(1616796) Gas panel - Central venous blood
0
10
0.00
0.21
0.0
4.4
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
12
0.00
0.21
0.0
2.8
—
—
—
0
0
(3012544) pH of Venous blood
6
47
1.30
0.21
1.2
2.7
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
14
0.00
0.20
0.0
3.7
—
18.6
—
0
14
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
0
14
0.00
0.20
0.0
2.1
—
0.2
—
0
7
(3014051) Protein [Presence] in Urine by Test strip
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
40
374
1.16
0.19
3.3
3.0
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
7
61
1.16
0.18
1.1
3.5
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
5
65
0.75
0.18
1.2
1.8
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
8
67
1.22
0.17
16.5
7.8
—
—
—
0
0
(3002256) Pathology report gross observation
6
76
0.77
0.16
1.2
1.3
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
52
539
0.86
0.15
5.1
4.8
mmol/mol
38.6
39.1
0.17
47
509
(3041096) Erythrocytes [Presence] in Urine by Automated
19
171
1.15
0.14
3.3
3.5
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
13
113
1.18
0.14
3.8
5.3
%
17.5
21.1
—
6
55
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
12
105
1.17
0.12
1.8
1.4
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
10
86
1.19
0.11
2.9
2.9
mmol/l
2.5
2.5
—
10
75
(3013512) EKG study
17
154
1.14
0.11
2.5
3.4
—
—
—
0
0
(3044889) 12 lead EKG panel
40
384
1.10
0.09
3.4
3.7
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
6
55
1.10
0.09
1.2
1.1
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
17
157
1.11
0.08
2.5
1.6
mmol/l
1.3
1.2
0.20
12
138
(3019550) Sodium [Moles/volume] in Serum or Plasma
58
592
0.88
0.08
20.3
13.8
mmol/l
139.3
139.8
0.80
58
578
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
8
76
1.06
0.08
2.1
2.0
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
13
141
0.90
0.06
1.3
1.4
nmol/l
19.9
22.8
0.35
13
122
(3009542) Hematocrit [Volume Fraction] of Blood
52
531
0.92
0.05
26.1
13.2
%
41.4
40.0
1.18
29
406
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
55
560
0.92
0.05
4.4
4.1
mmol/l
6.0
5.8
0.98
50
523
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
56
569
0.92
0.04
5.7
4.2
mmol/l
4.5
4.7
1.13
50
532
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
24
231
1.06
0.03
4.3
3.6
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
57
578
0.93
0.03
4.6
4.6
mmol/l
2.7
2.8
0.42
52
535
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
21
213
0.98
0.00
2.1
1.8
pmol/l
88.3
99.6
0.43
13
104
(3023103) Potassium [Moles/volume] in Serum or Plasma
59
591
0.99
0.00
20.2
13.9
mmol/l
3.9
4.0
1.41
59
577
(3029937) Albumin [Presence] in Urine by Test strip
16
156
1.03
0.00
4.8
3.8
estimate
0.0
0.0
—
7
51
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
15
146
1.03
0.00
4.9
5.4
ug/l
2.2
1.8
0.19
15
126
(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum
0
6
0.00
0.00
0.0
1.5
—
16.8
—
0
6
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
6
62
0.96
0.00
3.7
2.7
u/l
25.5
32.8
—
6
53
(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3001788) Aldosterone [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
190.7
—
0
6
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
6
0.00
0.00
0.0
2.2
—
14.2
—
0
6
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
0
7
0.00
0.00
0.0
3.3
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
1.0
—
106.0
—
0
5
(3000034) Microalbumin [Mass/volume] in Urine
0
5
0.00
0.00
0.0
5.0
—
41.9
—
0
5
(3022145) Colonoscopy Study observation
7
70
1.00
0.00
1.6
1.4
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
(3000492) Spirometry study
5
50
1.00
0.00
1.4
1.3
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
0.3
—
0
5
(3036669) Protein S actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.2
—
89.0
—
0
5
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
2.5
—
4.0
—
0
8
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
7
70
1.00
0.00
2.0
1.8
—
—
—
0
0
(4146454)
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
3.2
—
0
5
(3041354) Potassium [Moles/volume] in Venous blood
0
5
0.00
0.00
0.0
1.0
—
4.2
—
0
5
(3017569) Oxygen content in Arterial blood
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint L12_PSORI_ACRODERM and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_PSORI_ACRODERM.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: L12_PSORI_ACRODERM – Acrodermatitis continua

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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