No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
443 |
4. Check minimum number of eventsNone |
443 |
5. Include endpointsNone |
443 |
6. Filter based on genotype QC (FinnGen only) |
443 |
Control definitions (FinnGen only)
- Control exclude
- N14_FEMALEGENNONINF
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF6
Similar endpoints
↥List of similar endpoints to
Premenstrual syndrome
based on the number of shared cases.
Similar with more cases:
- Pain and other conditions associated with female genital organs and menstrual cycle
- Noninflammatory disorders of female genital tract
- Genitourinary diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2345 | 2345 | - |
| Only index persons | 2313 | 2313 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.07 | - |
| Only index persons | 0.09 | 0.09 | - |
| Median age at first event (years) | |||
| Whole population | - | 39.17 | - |
| Only index persons | - | 39.11 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 443 | 443 | - |
| Unadjusted period prevalence (%) | 0.15 | 0.15 | - |
| Median age at first event (years) | 39.93 | 39.93 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 392
- Matched controls
- 3920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N94.3
ICD-10 Finland
Premenstrual tension syndrome
3807.5
323.0
372
18
N95.1
ICD-10 Finland
Menopausal and female climacteric states
+∞
67.7
63
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
6.1
57.7
216
660
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
13.9
52.3
94
87
LCA06
NOMESCO Finland
Biopsy of endometrium
16.7
50.9
84
63
N06AB04
ATC
citalopram; systemic
5.0
40.7
164
494
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
12.7
39.1
72
68
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
16.7
33.4
54
37
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
3.8
28.7
151
549
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
15.5
28.4
47
34
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
5.6
28.3
90
197
G03DB01
ATC
dydrogesterone; oral
4.2
27.9
124
386
N94.5
ICD-10 Finland
Secondary dysmenorrhoea
67.1
27.4
31
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.4
27.3
192
869
N84.0
ICD-10 Finland
Polyp of corpus uteri
289.8
27.1
27
*
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
77.9
26.2
29
*
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
+∞
25.3
24
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
5.0
24.3
86
210
TLC00
NOMESCO Finland
Insertion of intrauterine device
7.2
24.1
61
98
N06AB03
ATC
fluoxetine; oral
4.4
23.8
96
268
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
3.1
21.7
164
747
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
20.4
21.7
32
17
N97.9
ICD-10 Finland
Female infertility, unspecified
26.0
21.2
29
12
N92.4
ICD-10 Finland
Excessive bleeding in the premenopausal period
39.6
21.0
26
7
J02AC01
ATC
fluconazole; systemic
2.8
21.0
250
1511
6254A
ICD-9 Finland
Pain and other symptoms associated with female genital organs, Premenstrual tension syndromes
+∞
21.0
20
*
LCA16
NOMESCO Finland
Destruction of endometrium
+∞
18.9
18
*
N06AB10
ATC
escitalopram; oral
2.9
17.9
139
628
Z30.2
ICD-10 Finland
Sterilization
3.8
17.9
84
264
N80.0
ICD-10 Finland
Endometriosis of uterus
188.1
17.7
18
*
N06AX16
ATC
venlafaxine; oral
3.4
17.6
97
346
N05BA04
ATC
oxazepam; oral
2.9
17.6
131
577
ULC02
NOMESCO Finland
Hysteroscopy
13.5
16.9
29
23
A02BC05
ATC
esomeprazole; systemic
2.5
15.8
162
850
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
166.3
15.6
16
*
N80.9
ICD-10 Finland
Endometriosis, unspecified
39.8
15.5
19
5
M03BX02
ATC
tizanidine; oral
2.5
15.0
280
1979
N81.6
ICD-10 Finland
Rectocele
19.3
14.9
22
12
N95.0
ICD-10 Finland
Postmenopausal bleeding
19.3
14.9
22
12
N87.0
ICD-10 Finland
Mild cervical dysplasia
155.5
14.6
15
*
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
5.4
14.5
44
89
B02AA02
ATC
tranexamic acid; systemic
3.3
14.3
80
286
N83.1
ICD-10 Finland
Corpus luteum cyst
44.2
14.2
17
*
A02BC02
ATC
pantoprazole; systemic
2.3
14.1
245
1645
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
31.3
14.0
18
6
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.3
13.9
242
1620
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.1
13.9
88
339
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
10.6
13.7
26
26
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
+∞
13.6
13
*
N94.4
ICD-10 Finland
Primary dysmenorrhoea
19.1
13.5
20
11
A06AC01
ATC
ispaghula (psylla seeds); oral
2.9
13.5
95
393
M79.7
ICD-10 Finland
Fibromyalgia
6.6
12.9
33
54
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
3.3
12.8
70
243
C07AA05
ATC
propranolol; systemic
2.6
12.6
111
525
XLA10
NOMESCO Finland
NA
6.1
12.6
34
60
R51.80
ICD-10 Finland
Headache
2.9
12.5
85
344
N80.1
ICD-10 Finland
Endometriosis of ovary
134.1
12.5
13
*
G03DA02
ATC
medroxyprogesterone; systemic (pregnen (4) derivatives)
4.5
12.2
44
108
JAL21
NOMESCO Finland
Laparoscopic excision or destruction of lesion of peritoneum
48.2
11.9
14
*
P01AB01
ATC
metronidazole; oral, rectal
2.2
11.9
183
1127
N06AB06
ATC
sertraline; oral
3.0
11.8
72
271
G03DC02
ATC
norethisterone; oral
3.5
11.8
58
187
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
17.1
11.8
18
11
N81.1
ICD-10 Finland
Cystocele
23.7
11.7
16
7
N06AB05
ATC
paroxetine; oral
3.9
11.6
48
134
N87.1
ICD-10 Finland
Moderate cervical dysplasia
+∞
11.5
11
*
N06AX21
ATC
duloxetine; oral
3.2
11.5
64
226
A02BC03
ATC
lansoprazole; oral
2.5
11.4
102
484
P03
ICPC
Feeling depressed
3.1
11.3
67
245
J01DA01
ATC
[U] cefalexin; systemic
2.1
11.3
265
1936
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
4.2
11.2
43
112
N05BA12
ATC
alprazolam; oral
3.5
11.1
53
167
X09
ICPC
Premenstrual symptom/complaint
44.6
11.0
13
*
N02BE01
ATC
paracetamol; systemic, rectal
2.5
11.0
332
2706
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.5
10.9
52
164
R03AC02
ATC
salbutamol; inhalant
2.1
10.8
229
1590
A02BA02
ATC
ranitidine; systemic
2.9
10.8
69
268
R06AX27
ATC
desloratadine; oral
2.1
10.7
154
907
N05AH04
ATC
quetiapine; oral
2.5
10.6
93
433
C03DA01
ATC
spironolactone; oral
4.7
10.6
36
83
J01DB01
ATC
cefalexin; oral
2.4
10.6
330
2694
M01AE02
ATC
naproxen; oral, rectal
2.0
10.5
239
1699
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
+∞
10.5
10
*
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
+∞
10.5
10
*
N95.2
ICD-10 Finland
Postmenopausal atrophic vaginitis
+∞
10.5
10
*
LGA21
NOMESCO Finland
Laparoscopic sterilisation by constriction of Fallopian tubes
3.9
10.4
43
120
EB1AA
NOMESCO Finland
Tooth X-ray examination
2.0
10.4
238
1692
N94.6
ICD-10 Finland
Dysmenorrhoea, unspecified
10.0
10.4
20
21
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
3.0
10.4
62
229
LCD10
NOMESCO Finland
Vaginal hysterectomy
19.4
10.3
15
8
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
10.2
125
686
N03AX16
ATC
pregabalin; oral
2.5
10.1
89
414
J31.0
ICD-10 Finland
Chronic rhinitis
3.6
10.0
45
135
ULA02
NOMESCO Finland
Kolposcopy
3.2
10.0
55
190
N02AX02
ATC
tramadol; systemic, rectal
2.2
10.0
134
762
J45.9
ICD-10 Finland
Asthma, unspecified
2.7
10.0
74
313
SAA01
NOMESCO Finland
Simple examination of mouth
2.2
10.0
309
2467
TLC02
NOMESCO Finland
Simple extraction of IUD
4.5
10.0
35
84
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
10.0
93
445
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
2.2
9.8
118
640
N03AX12
ATC
gabapentin; oral
2.8
9.8
66
261
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
5.5
9.7
28
54
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.7
9.6
68
279
R06.0
ICD-10 Finland
Dyspnoea
2.5
9.5
81
368
N97.0
ICD-10 Finland
Female infertility associated with anovulation
102.4
9.5
10
*
8113
FHL
Fractional scraping
12.8
9.4
16
13
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
+∞
9.4
9
*
M79.6
ICD-10 Finland
Pain in limb
2.1
9.3
139
822
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.1
9.3
134
784
JAH01
NOMESCO Finland
Laparoscopy
5.6
9.2
26
49
G43.9
ICD-10 Finland
Migraine, unspecified
3.3
9.2
47
156
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.5
9.2
77
346
R53
ICD-10 Finland
Malaise and fatigue
2.4
9.2
89
434
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
7.3
9.1
21
30
1410
FHL
Laparoscopy
10.4
9.1
17
17
M79.1
ICD-10 Finland
Myalgia
2.7
9.1
68
287
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.5
9.0
76
344
P29
ICPC
Psychological sympt/compl other
3.4
9.0
43
136
M25.5
ICD-10 Finland
Pain in joint
2.1
9.0
124
708
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
24.7
9.0
12
5
P01
ICPC
Feeling anxious/nervous/tense
2.4
8.9
78
361
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.9
8.8
36
100
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
8.8
86
418
D01
ICPC
Abdominal pain/cramps general
2.9
8.7
55
211
N92.5
ICD-10 Finland
Other specified irregular menstruation
5.7
8.7
24
44
H02AB06
ATC
prednisolone; systemic
1.9
8.7
172
1130
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.5
8.6
71
319
D19
ICPC
Teeth/gum symptom/complaint
2.0
8.5
127
748
N80.4
ICD-10 Finland
Endometriosis of rectovaginal septum and vagina
91.9
8.4
9
*
N06AX26
ATC
vortioxetine; oral
3.2
8.4
43
144
N97.1
ICD-10 Finland
Female infertility of tubal origin
+∞
8.4
8
*
N03AX09
ATC
lamotrigine; oral
3.5
8.2
38
118
N06AX12
ATC
bupropion; oral
3.0
8.2
47
170
LCA10
NOMESCO Finland
Curettage of body of uterus
17.6
8.1
12
7
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
6.1
8.1
21
36
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
2.1
8.0
111
630
G44.2
ICD-10 Finland
Tension-type headache
2.4
8.0
73
344
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
8.0
79
385
G01AA10
ATC
clindamycin; vaginal
2.1
8.0
99
538
M54.5
ICD-10 Finland
Low back pain
1.9
7.9
135
833
R02
ICPC
Shortness of breath/dyspnoea
3.1
7.9
44
154
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.5
7.9
27
64
R03BA05
ATC
fluticasone; inhalant
2.2
7.8
84
428
D11
ICPC
Diarrhoea
2.5
7.8
64
286
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.7
7.7
55
226
P76
ICPC
Depressive disorder
2.9
7.7
46
171
N01
ICPC
Headache
2.6
7.7
58
248
N06BA04
ATC
methylphenidate; oral
5.6
7.6
21
39
LDA10
NOMESCO Finland
Curettage of cervix uteri
4.0
7.6
29
76
J45
ICD-10 Finland
Asthma
2.8
7.6
48
185
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
7.5
208
1505
M01AE03
ATC
ketoprofen; systemic, rectal
1.9
7.4
130
804
R42
ICD-10 Finland
Dizziness and giddiness
2.4
7.4
67
314
LBE20
NOMESCO Finland
Laparoscopic bilateral salpingectomy
13.7
7.4
12
9
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.3
7.4
69
328
UJF32
NOMESCO Finland
Coloscopy
2.3
7.4
69
328
M01AH02
ATC
rofecoxib; oral
3.0
7.4
42
150
F32
ICD-10 Finland
Depressive episode
3.2
7.4
37
122
K07.60
ICD-10 Finland
Snapping jaw
3.2
7.4
38
128
X07
ICPC
Menstruation irregular/frequent
9.6
7.3
14
15
F41.1
ICD-10 Finland
Generalized anxiety disorder
3.1
7.3
41
144
N97.4
ICD-10 Finland
Female infertility associated with male factors
+∞
7.3
7
*
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
7.3
68
323
KMAK
NOMESCO Finland
NA
1.8
7.2
240
1836
N05BA01
ATC
diazepam; systemic, rectal
2.6
7.2
53
223
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
5.2
7.2
21
42
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.8
7.1
29
81
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
3.8
7.1
29
81
A04
ICPC
Weakness/tiredness general
2.6
7.1
54
230
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.8
7.0
28
77
C07AB07
ATC
bisoprolol; oral
1.9
7.0
112
670
K58
ICD-10 Finland
Irritable bowel syndrome
6.0
7.0
18
31
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.3
7.0
64
302
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
7.7
7.0
15
20
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.9
6.9
41
152
N94.1
ICD-10 Finland
Dyspareunia
14.1
6.9
11
8
J01AA02
ATC
doxycycline; systemic
1.9
6.9
294
2417
K80
ICPC
Cardiac arrhythmia NOS
3.6
6.8
29
85
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.6
6.8
29
85
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
40.8
6.8
8
*
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.6
6.8
22
50
N06AX03
ATC
mianserin; oral
4.2
6.7
24
60
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.7
6.7
46
186
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
6.6
31
98
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.1
6.6
35
121
C07AB02
ATC
metoprolol; systemic
2.6
6.6
48
199
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.0
6.5
92
522
F45.8
ICD-10 Finland
Other somatoform disorders
2.6
6.5
46
190
L14
ICPC
Leg/thigh symptom/complaint
3.5
6.5
29
88
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.1
6.5
24
62
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.0
6.5
37
133
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
6.5
114
702
N05CF01
ATC
zopiclone; oral
1.9
6.5
103
611
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
70.9
6.4
7
*
X02
ICPC
Menstrual pain
5.3
6.4
18
35
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
5.7
6.4
17
31
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.2
6.3
67
339
K04
ICPC
Palpitations/awareness of heart
3.7
6.3
26
74
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.7
6.3
26
74
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
11.3
6.3
11
10
N83.0
ICD-10 Finland
Follicular cyst of ovary
18.4
6.3
9
5
N06AX11
ATC
mirtazapine; oral
1.8
6.3
121
766
6262A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Excessive or frequent menstruation[HYPERMENORRHOEA]
+∞
6.3
6
*
TLW00
NOMESCO Finland
Insemination
+∞
6.3
6
*
J05AB01
ATC
aciclovir; systemic
2.0
6.3
87
493
N64.3
ICD-10 Finland
Galactorrhoea not associated with childbirth
27.1
6.2
8
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
2.9
6.2
36
131
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
4.4
6.2
21
50
F90.0
ICD-10 Finland
Disturbance of activity and attention
4.4
6.2
21
50
WX290
NOMESCO Finland
Other blockade of nerve
1.7
6.2
206
1543
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
4.0
6.2
23
60
R01AD09
ATC
mometasone; nasal
1.7
6.2
199
1480
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
6.1
52
237
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
6.1
56
263
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.7
6.1
168
1190
R00.2
ICD-10 Finland
Palpitations
2.9
6.0
35
128
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
6.0
136
908
SPAT1104
SPAT
Monitoring of emergency patient
3.7
6.0
24
67
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
107
317
4.13
32.52
1.5
1.3
13.7
25.5
iu/l
4.76
94
279
193
999
2.65
21.75
1.9
1.7
103.4
97.5
pmol/l
0.78
104
550
40
72
6.01
21.73
1.3
1.2
9.1
15.2
u/l
1.22
32
58
389
2999
3.44
17.54
6.1
4.1
14.2
14.3
pmol/l
0.07
381
2821
169
921
2.35
15.98
1.4
1.2
1.6
1.9
u/ml
0.16
41
267
34
71
5.10
15.69
1.4
1.3
7.0
28.5
u/l
5.72
24
61
141
722
2.40
15.26
2.0
1.9
308.3
142.5
u/l
0.35
135
684
282
1925
2.28
15.24
7.2
9.1
3.8
4.0
e9/l
1.10
253
1708
417
3448
4.57
14.95
7.2
4.5
1.6
1.8
mu/l
3.64
409
3279
277
1892
2.24
14.74
3.7
2.7
58.8
66.5
ug/l
1.13
272
1806
169
956
2.24
14.32
2.6
3.3
2.4
2.3
mmol/l
0.33
155
874
85
353
2.74
14.16
1.7
1.6
1089.1
1218.4
nmol/l
0.74
77
269
154
843
2.27
14.09
2.1
2.1
54.7
57.6
u/l
0.52
144
790
324
2386
2.33
13.99
6.3
6.4
70.7
73.6
u/l
0.79
312
2257
301
2154
2.24
13.89
4.8
3.3
1649.4
973.6
e6/l
—
5
18
332
2495
2.32
13.27
4.7
3.6
7.9
9.8
mm/h
4.63
319
2342
218
1398
2.10
13.10
2.8
2.1
77.6
73.0
nmol/l
1.71
207
1315
98
454
2.49
13.00
1.7
1.7
1.4
1.3
%
1.05
87
401
183
1102
2.13
12.96
3.8
4.3
37.0
36.8
g/l
0.24
175
1033
413
3467
3.82
12.85
11.2
8.9
139.4
139.6
mmol/l
0.86
408
3362
76
316
2.70
12.55
1.8
2.1
336.4
385.7
nmol/l
1.87
69
293
412
3477
3.64
12.20
11.2
9.0
3.9
3.9
mmol/l
0.05
405
3359
123
651
2.23
11.93
3.7
2.9
1.0
1.0
kg/l
0.02
16
95
132
734
2.14
11.22
2.4
1.9
—
—
—
0
0
163
993
2.01
10.76
1.6
1.3
—
—
—
0
0
141
818
2.06
10.63
2.5
2.0
—
—
—
0
0
17
28
6.27
9.99
2.1
1.9
—
—
—
0
0
327
2569
2.04
9.86
3.4
2.5
32.5
34.1
u/l
0.18
321
2455
418
3661
3.51
9.52
11.5
9.1
15.8
19.6
mg/l
2.11
329
2715
361
2971
2.16
9.17
4.8
3.8
37.0
37.5
mmol/mol
0.70
345
2819
229
1658
1.79
8.25
3.3
4.0
6.3
6.3
mmol/l
0.00
206
1487
221
1584
1.79
8.23
3.4
2.8
0.0
0.0
estimate
0.00
31
327
191
1316
1.79
8.10
5.9
5.7
1.2
1.2
mmol/l
2.05
176
1121
94
514
2.05
8.09
2.0
1.8
—
—
—
0
0
164
1080
1.82
8.08
1.8
1.6
—
—
—
0
0
83
438
2.10
7.84
2.4
2.3
2.4
2.4
mmol/l
0.22
71
381
387
3334
2.27
7.81
4.4
3.2
5.5
5.6
mmol/l
0.79
375
3132
207
1479
1.75
7.61
3.9
5.4
8.9
10.0
umol/l
1.26
195
1396
172
1172
1.76
7.42
4.8
5.0
1.2
1.2
mmol/l
2.32
164
1086
425
3845
3.59
7.41
10.1
7.9
24.2
23.7
u/l
0.19
418
3744
216
1577
1.72
7.24
4.7
3.9
0.0
0.0
estimate
0.50
31
328
110
661
1.88
7.13
1.5
1.3
13.8
10.7
u/ml
0.13
32
279
93
529
1.96
7.10
1.3
1.4
21.9
20.2
nmol/l
0.64
83
478
23
66
3.62
7.08
1.2
1.3
337.7
365.0
ug/g
0.20
12
32
117
724
1.84
6.89
2.4
2.0
2.7
2.6
mg/l
0.07
101
631
94
546
1.92
6.72
1.7
1.6
437.1
45732140.2
pmol/l
1.07
88
492
114
709
1.82
6.57
1.5
1.3
22.0
23.7
iu/ml
0.07
37
215
215
1597
1.67
6.54
3.6
2.8
0.0
0.0
estimate
0.00
31
330
133
869
1.76
6.48
2.5
2.4
10.2
20.3
ng/l
1.95
51
380
377
3278
2.01
6.45
8.5
7.7
92.3
92.6
ml/min/173m2
0.13
322
2642
120
764
1.78
6.38
1.6
1.5
0.5
0.8
mg/l
2.59
79
566
60
302
2.14
6.36
1.2
1.2
83.7
262.8
u/ml
1.45
54
279
35
140
2.63
6.19
1.8
1.8
—
—
—
0
0
73
408
1.94
5.81
1.7
1.7
—
—
—
0
0
65
349
2.01
5.80
1.3
1.2
101.2
152.1
iu/ml
0.43
23
156
29
111
2.73
5.60
1.8
1.5
—
—
—
0
0
27
100
2.81
5.54
1.2
1.2
—
—
—
0
0
38
168
2.38
5.48
1.4
1.7
—
—
—
0
0
162
1163
1.62
5.37
3.3
3.0
26.0
26.9
u/l
0.27
153
1120
31
128
2.53
5.17
1.1
1.1
3.4
4.3
u/ml
—
5
29
59
319
1.98
5.16
2.4
2.3
23.8
23.6
%
0.03
52
275
200
1523
1.57
5.10
3.6
3.7
—
—
—
0
0
372
3289
1.82
5.08
4.4
3.7
—
—
—
0
0
11
24
4.67
4.80
1.1
1.0
—
—
—
0
0
395
3596
1.91
4.38
4.4
3.4
2.9
2.9
mmol/l
0.05
383
3415
45
235
2.02
4.34
2.0
1.7
—
—
—
0
0
69
419
1.77
4.21
2.3
2.8
373.3
664.8
ng/l
0.58
60
342
44
232
2.00
4.14
1.1
1.0
—
—
—
0
0
50
277
1.91
4.09
2.1
2.3
30.1
41.1
u/l
1.00
43
241
99
669
1.62
4.06
2.0
2.0
283.0
3564.4
umol/l
1.83
84
603
163
1240
1.50
3.92
3.5
2.8
—
—
—
0
0
102
701
1.59
3.89
1.8
1.8
—
—
—
0
0
8
11
7.38
3.87
2.0
1.8
—
—
—
0
0
71
447
1.70
3.81
3.3
2.8
1521.4
421.1
ng/l
0.32
39
220
56
330
1.80
3.78
4.1
2.7
33.9
33.0
%
0.25
48
241
64
397
1.72
3.63
3.2
3.6
0.8
0.8
mmol/l
0.05
59
374
388
3558
1.73
3.59
4.1
3.2
4.9
4.9
mmol/l
0.19
376
3392
7
9
7.88
3.57
2.7
4.8
10.4
19.3
umol/l
—
7
9
23
99
2.40
3.56
1.1
1.2
—
—
—
0
0
44
245
1.88
3.56
1.4
1.3
—
23.4
—
0
14
25
112
2.31
3.55
1.5
1.2
—
1.2
—
0
6
23
100
2.37
3.49
1.1
1.2
—
—
—
0
0
393
3626
1.74
3.43
13.2
10.3
39.3
39.5
%
0.22
321
3029
372
3388
1.61
3.37
3.8
2.9
1.2
1.2
mmol/l
0.30
360
3218
23
104
2.28
3.21
1.6
1.2
46.4
3.1
u/ml
—
5
20
10
28
3.63
3.21
1.5
1.4
—
—
—
0
0
10
28
3.63
3.21
1.5
1.4
—
—
—
0
0
10
28
3.63
3.21
1.5
1.4
—
—
—
0
0
16
61
2.68
3.17
1.3
1.6
85.2
113.5
u/ml
—
5
15
45
264
1.78
3.10
5.3
5.7
1.1
1.0
mmol/l
0.24
38
250
46
272
1.77
3.09
4.9
4.4
—
—
—
0
0
16
62
2.64
3.08
1.0
1.1
—
—
—
0
0
10
29
3.50
3.06
1.5
1.4
—
—
—
0
0
10
29
3.50
3.06
1.5
1.4
—
—
—
0
0
10
29
3.50
3.06
1.4
1.4
—
—
—
0
0
384
3545
1.62
3.04
4.1
3.2
1.5
1.6
mmol/l
0.35
373
3380
44
259
1.78
3.00
1.5
1.4
—
—
—
0
0
26
129
2.08
2.92
1.5
2.2
—
—
—
0
0
16
64
2.56
2.90
1.4
1.4
—
—
—
0
0
52
325
1.68
2.88
1.8
1.7
1352.4
5773.5
u/l
1.84
14
125
8
18
4.51
2.80
1.0
1.1
—
—
—
0
0
17
72
2.42
2.76
1.0
1.1
1.7
3.4
u/ml
—
7
40
36
205
1.82
2.75
1.6
1.9
3.8
3.8
mg/l
0.01
27
131
58
379
1.61
2.71
1.6
1.7
—
—
—
0
0
41
245
1.74
2.68
1.4
1.6
—
—
—
0
0
10
34
2.99
2.42
1.1
1.4
—
—
—
0
0
6
13
4.66
2.28
1.2
1.3
—
—
—
0
0
7
19
3.73
2.16
1.0
1.1
0.3
0.3
g/l
—
7
13
40
253
1.64
2.15
1.5
1.6
—
—
—
0
0
106
823
1.38
2.12
3.9
3.1
0.0
0.0
estimate
0.50
28
325
19
96
2.02
2.08
2.5
2.4
7.3
4.9
umol/l
0.70
11
70
96
737
1.39
2.05
2.9
2.5
0.2
0.5
e6/l
1.93
72
529
57
397
1.50
2.04
2.2
2.4
3.0
4.7
e6/l
0.93
34
194
31
186
1.72
2.03
1.4
1.1
—
—
—
0
0
8
26
3.11
2.02
1.4
1.2
—
—
—
0
0
22
120
1.88
1.96
1.0
1.1
0.6
0.8
u/ml
—
8
45
11
46
2.43
1.86
1.5
1.2
—
—
—
0
0
11
46
2.43
1.86
1.5
1.2
—
—
—
0
0
33
207
1.64
1.86
10.8
11.8
1.0
1.2
inr
—
5
33
9
35
2.60
1.81
1.2
1.2
—
—
—
0
0
23
132
1.78
1.77
3.5
2.6
5.3
4.8
kpa
0.33
23
124
7
24
2.95
1.73
1.1
1.5
—
—
—
0
0
5
13
3.88
1.72
1.4
1.3
14.8
13.4
pmol/l
—
5
13
7
25
2.83
1.65
1.1
1.5
—
—
—
0
0
5
14
3.60
1.62
2.8
3.1
—
—
—
0
0
8
32
2.53
1.60
1.3
1.2
0.5
0.5
nmol/l
—
8
32
57
420
1.41
1.56
2.4
2.2
0.5
1.0
e6/l
1.88
35
220
5
15
3.36
1.52
1.4
1.1
—
—
—
0
0
21
124
1.73
1.50
2.4
2.1
3.1
4.8
iu/l
—
7
55
27
171
1.62
1.50
3.8
3.7
6.1
5.8
kpa
0.77
27
163
9
39
2.33
1.43
1.4
1.2
—
—
—
0
0
9
40
2.28
1.41
1.1
1.2
—
—
—
0
0
35
247
1.45
1.23
1.4
1.3
346.0
236.2
miu/ml
0.73
19
133
20
124
1.64
1.23
1.4
1.3
—
—
—
0
0
8
41
1.97
1.09
1.4
1.4
—
—
—
0
0
14
228
0.60
1.07
1.6
1.7
—
—
—
0
0
19
122
1.58
1.04
1.4
1.1
—
—
—
0
0
18
115
1.59
1.01
3.4
3.6
129.3
129.1
g/l
0.02
18
110
9
48
1.89
1.01
1.2
1.2
—
—
—
0
0
7
35
2.02
1.00
1.7
1.7
—
—
—
0
0
5
23
2.19
0.98
1.4
1.3
—
—
—
0
0
6
119
0.50
0.95
1.7
1.5
98.7
97.5
%
—
6
111
12
70
1.73
0.93
1.1
1.2
—
—
—
0
0
6
28
2.16
0.92
1.3
1.3
—
—
—
0
0
17
112
1.54
0.86
1.4
1.5
—
—
—
0
0
95
817
1.21
0.86
1.7
1.6
1.3
1.3
mmol/l
0.35
83
738
14
89
1.59
0.82
1.5
1.9
—
—
—
0
0
45
359
1.28
0.80
1.7
2.1
3.8
5.5
umol/l
1.32
39
301
6
34
1.77
0.76
1.3
1.2
—
—
—
0
0
11
70
1.59
0.65
1.1
1.1
—
—
—
0
0
59
500
1.21
0.64
1.5
1.5
—
—
—
0
0
16
113
1.43
0.62
3.3
2.4
1.0
1.6
mmol/l
—
9
85
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
18
132
1.38
0.58
1.8
2.1
42.8
39.8
u/l
0.35
18
125
30
240
1.27
0.55
2.7
2.5
82.3
79.0
ml/min/173m2
—
10
83
6
38
1.59
0.54
1.0
2.7
—
—
—
0
0
15
108
1.40
0.53
2.1
1.8
—
—
—
0
0
14
100
1.41
0.52
1.6
1.8
—
—
—
0
0
13
93
1.41
0.48
3.8
4.2
25.0
24.4
mmol/l
0.34
13
84
7
46
1.53
0.48
1.1
1.3
—
—
—
0
0
28
228
1.24
0.46
5.4
6.8
103.5
104.8
mmol/l
0.83
28
223
21
262
0.79
0.43
1.4
1.5
—
—
—
0
0
5
33
1.52
0.41
1.2
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
15
193
0.77
0.40
1.3
1.5
—
—
—
0
0
8
61
1.32
0.39
1.0
1.4
—
—
—
0
0
45
512
0.87
0.38
1.4
1.5
—
—
—
0
0
19
152
1.26
0.37
1.2
2.5
69.1
67.9
g/l
0.37
19
143
31
263
1.19
0.37
1.6
1.4
—
—
—
0
0
14
108
1.31
0.35
2.0
2.2
2.6
6.7
ug/l
—
9
93
6
46
1.31
0.33
1.0
1.2
—
—
—
0
0
16
193
0.82
0.27
1.7
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
2.1
—
23.0
—
0
12
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
6
49
1.23
0.20
1.3
6.5
—
96.7
—
0
6
6
51
1.18
0.19
1.3
1.4
—
—
—
0
0
10
81
1.24
0.19
1.1
1.3
—
—
—
0
0
7
58
1.21
0.18
1.1
1.5
—
—
—
0
0
7
61
1.15
0.17
3.7
2.7
—
—
—
0
0
9
82
1.10
0.15
1.1
1.5
—
—
—
0
0
5
48
1.04
0.09
1.2
1.1
—
—
—
0
0
27
253
1.07
0.08
2.0
2.5
—
—
—
0
0
12
107
1.12
0.08
1.1
1.1
—
—
—
0
0
11
123
0.89
0.08
6.3
12.2
25.2
24.7
mmol/l
0.18
11
116
7
66
1.06
0.08
1.3
2.1
11.5
10.6
g/l
—
7
60
8
76
1.05
0.07
1.3
1.4
—
—
—
0
0
8
78
1.03
0.07
1.3
1.4
—
—
—
0
0
34
325
1.05
0.06
1.2
1.4
—
—
—
0
0
27
258
1.05
0.05
1.4
1.4
—
—
—
0
0
27
258
1.05
0.05
1.4
1.4
—
—
—
0
0
27
258
1.05
0.05
1.4
1.4
—
—
—
0
0
27
258
1.05
0.05
1.4
1.4
—
—
—
0
0
27
282
0.95
0.04
1.5
1.5
—
—
—
0
0
23
220
1.05
0.03
6.4
10.0
1.5
1.1
mmol/l
0.21
17
171
19
181
1.05
0.03
7.5
11.4
120.4
120.0
g/l
0.03
19
175
12
112
1.07
0.03
7.9
9.6
0.8
0.7
%
0.36
12
112
14
142
0.99
0.00
1.3
1.5
—
—
—
0
0
11
111
0.99
0.00
8.5
9.7
1.2
1.3
%
0.27
11
111
8
81
0.99
0.00
1.1
1.2
—
—
—
0
0
7
76
0.92
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
1.7
—
0
6
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
0.00
1.3
2.0
6.4
7.3
g/l
—
7
63
0
6
0.00
0.00
0.0
1.8
—
1.2
—
0
6
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
7
71
0.99
0.00
1.3
2.0
2.6
3.1
g/l
—
7
59
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
2.7
—
48.2
—
0
6
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
0.00
1.3
2.0
3.2
3.9
g/l
—
7
58
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
0.00
1.3
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_PREMENSTSYNDROM and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have N14_PREMENSTSYNDROM.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: N14_PREMENSTSYNDROM – Premenstrual syndrome
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data