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Premenstrual syndrome

Endpoint Browser PheWeb

N14_PREMENSTSYNDROM

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N94.3
  • Hospital discharge: ICD-9 — 6254A
  • Cause of death: ICD-10 — N94.3
  • Cause of death: ICD-9 — 6254A

2 out of 7 registries used, show all original rules.

476

4. Check minimum number of events

None

476

5. Include endpoints

None

476

6. Filter based on genotype QC (FinnGen only)

454

Control definitions (FinnGen only)

Control exclude
N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2345 2345 -
Only index persons 2313 2313 -
Unadjusted period prevalence (%)
Whole population 0.07 0.07 -
Only index persons 0.09 0.09 -
Median age at first event (years)
Whole population - 39.17 -
Only index persons - 39.11 -

-FinnGen-

Key figures

All Female Male
Number of individuals 454 454 -
Unadjusted period prevalence (%) 0.16 0.16 -
Median age at first event (years) 39.92 39.92 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
476
Matched controls
4760
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N94.3
ICD-10 Finland
Premenstrual tension syndrome
3305.2
307.7
455
31
N95.1
ICD-10 Finland
Menopausal and female climacteric states
+∞
120.0
110
*
LCA06
NOMESCO Finland
Biopsy of endometrium
17.7
118.0
104
74
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
16.2
86.4
78
57
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
8.6
81.4
122
184
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
9.6
71.1
93
118
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
5.1
69.0
270
975
N06AB04
ATC
citalopram; systemic
4.9
61.0
199
612
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
10.8
55.1
63
66
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
5.6
51.1
117
264
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
16.4
48.2
42
28
TLC00
NOMESCO Finland
Insertion of intrauterine device
6.9
44.2
75
126
G03DB01
ATC
dydrogesterone; oral
4.3
43.8
147
448
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
5.2
42.7
103
241
N06AB03
ATC
fluoxetine; oral
4.5
40.7
119
325
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
3.5
40.0
230
999
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
3.6
39.4
196
775
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.3
35.9
252
1216
J02AC01
ATC
fluconazole; systemic
3.3
34.0
314
1759
ULC02
NOMESCO Finland
Hysteroscopy
11.7
33.2
35
32
G03DA02
ATC
medroxyprogesterone; systemic
6.5
33.1
58
100
N06AB10
ATC
escitalopram; oral
3.2
32.3
186
788
N84.0
ICD-10 Finland
Polyp of corpus uteri
121.8
32.1
34
*
N97.9
ICD-10 Finland
Female infertility, unspecified
36.2
31.5
40
12
N06AX16
ATC
venlafaxine; oral
3.5
29.4
126
443
N05BA04
ATC
oxazepam; oral
3.1
28.4
172
742
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
11.0
27.4
30
29
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
286.4
27.0
27
*
N94.5
ICD-10 Finland
Secondary dysmenorrhoea
31.3
26.7
35
12
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
39.3
26.5
33
9
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.4
26.2
72
184
A06AC01
ATC
ispaghula (psylla seeds); oral
3.2
26.0
132
511
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.3
25.3
118
433
B02AA02
ATC
tranexamic acid; systemic
3.5
25.2
100
332
N80.0
ICD-10 Finland
Endometriosis of uterus
263.2
24.9
25
*
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
5.2
24.5
53
111
LCA16
NOMESCO Finland
Destruction of endometrium
+∞
23.1
22
*
N06AX21
ATC
duloxetine; oral
3.5
22.4
90
300
N94.6
ICD-10 Finland
Dysmenorrhoea, unspecified
9.5
22.3
27
30
6254A
ICD-9 Finland
Pain and other symptoms associated with female genital organs, Premenstrual tension syndromes
+∞
22.0
21
*
R53
ICD-10 Finland
Malaise and fatigue
2.7
21.4
150
684
N95.2
ICD-10 Finland
Postmenopausal atrophic vaginitis
+∞
21.0
20
*
C07AA05
ATC
propranolol; systemic
2.7
20.9
150
692
N80.9
ICD-10 Finland
Endometriosis, unspecified
80.5
20.9
23
*
P03
ICPC
Feeling depressed
3.1
20.6
100
373
N94.4
ICD-10 Finland
Primary dysmenorrhoea
7.7
20.1
29
40
M79.7
ICD-10 Finland
Fibromyalgia
5.5
19.9
40
78
N92.4
ICD-10 Finland
Excessive bleeding in the premenopausal period
18.7
19.8
30
17
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
4.3
19.8
55
141
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.0
19.8
108
430
N05AH04
ATC
quetiapine; oral
2.8
19.3
122
524
A02BC05
ATC
esomeprazole; systemic
2.4
19.1
203
1118
N06AB05
ATC
paroxetine; oral
4.2
18.7
53
138
F41.1
ICD-10 Finland
Generalized anxiety disorder
3.7
18.7
64
191
N06AB06
ATC
sertraline; oral
3.0
18.5
97
376
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
4.3
18.5
51
130
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.9
18.2
103
417
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
186.7
17.6
18
*
A02BA02
ATC
ranitidine; systemic
3.1
17.4
82
299
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
3.2
17.2
75
261
A02BC02
ATC
pantoprazole; systemic
2.4
17.1
316
2173
Z30.2
ICD-10 Finland
Sterilization
2.9
16.9
92
363
N06AX26
ATC
vortioxetine; oral
3.4
16.9
65
209
P01
ICPC
Feeling anxious/nervous/tense
2.6
16.8
124
572
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
5.4
16.7
34
67
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.0
16.5
84
319
N81.6
ICD-10 Finland
Rectocele
15.0
16.5
27
19
N83.1
ICD-10 Finland
Corpus luteum cyst
41.7
16.5
20
5
N03AX12
ATC
[U] gabapentin; oral
2.9
16.4
88
344
TLC02
NOMESCO Finland
Simple extraction of IUD
4.4
16.2
42
102
N95.0
ICD-10 Finland
Postmenopausal bleeding
12.9
16.1
28
23
JAH01
NOMESCO Finland
Laparoscopy
5.8
15.9
30
55
A02BC03
ATC
lansoprazole; oral
2.5
15.9
127
607
M03BX02
ATC
tizanidine; oral
2.4
15.9
341
2460
G03DC02
ATC
norethisterone; oral
3.3
15.8
64
212
N06AX12
ATC
bupropion; oral
3.2
15.8
69
240
N80.1
ICD-10 Finland
Endometriosis of ovary
165.2
15.6
16
*
M03AX01
ATC
botulinum toxin; parenteral
7.3
15.4
23
33
A04
ICPC
Weakness/tiredness general
2.8
15.1
89
365
P76
ICPC
Depressive disorder
3.2
15.1
65
224
N02AX02
ATC
tramadol; systemic, rectal
2.2
14.9
175
985
N06AX11
ATC
mirtazapine; oral
2.2
14.7
175
988
ULA02
NOMESCO Finland
Kolposcopy
3.1
14.7
66
233
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
154.6
14.5
15
*
N03AX09
ATC
lamotrigine; oral
3.6
14.4
51
155
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
2.3
14.3
149
795
N81.1
ICD-10 Finland
Cystocele
23.1
14.3
20
9
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
14.2
81
326
R42
ICD-10 Finland
Dizziness and giddiness
2.6
14.2
100
448
N87.0
ICD-10 Finland
Mild cervical dysplasia
43.9
14.2
17
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.5
14.1
112
531
IGY99
NOMESCO Finland
Other psychiatric treatment contact
5.8
14.0
26
47
K30
ICD-10 Finland
Functional dyspepsia
2.9
13.9
70
264
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.5
13.8
102
467
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
6.7
13.8
22
34
R51.80
ICD-10 Finland
Headache
2.4
13.7
111
530
N05BA12
ATC
alprazolam; oral
3.1
13.7
61
214
JAL21
NOMESCO Finland
Laparoscopic excision or destruction of lesion of peritoneum
77.4
13.7
15
*
R52.2
ICD-10 Finland
Other chronic pain
5.3
13.5
28
56
XLA10, ,
NOMESCO Finland
4.2
13.3
36
90
K07.60
ICD-10 Finland
Snapping jaw
3.2
13.1
57
197
J01DA01
ATC
[U] cefalexin
2.1
13.1
319
2331
M79.0
ICD-10 Finland
Rheumatism, unspecified
5.2
13.0
27
54
C07AB07
ATC
bisoprolol; oral
2.2
13.0
149
822
N06AX03
ATC
mianserin; oral
4.9
13.0
29
62
C03DA01
ATC
spironolactone; oral
3.7
13.0
43
125
M01AH02
ATC
rofecoxib; oral
3.4
12.9
49
156
ZY010
NOMESCO Finland
Hospital outpatient
3.4
12.8
48
151
R02
ICPC
Shortness of breath/dyspnoea
3.1
12.8
59
211
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
12.7
113
561
X09
ICPC
Premenstrual symptom/complaint
33.0
12.6
16
5
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.4
12.6
99
465
M79.6
ICD-10 Finland
Pain in limb
2.0
12.6
212
1349
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
+∞
12.6
12
*
N87.1
ICD-10 Finland
Moderate cervical dysplasia
+∞
12.6
12
*
TLW00
NOMESCO Finland
Insemination
+∞
12.6
12
*
N97.0
ICD-10 Finland
Female infertility associated with anovulation
+∞
12.6
12
*
N97.4
ICD-10 Finland
Female infertility associated with male factors
+∞
12.6
12
*
L18
ICPC
Muscle pain
4.8
12.5
29
64
F34.1
ICD-10 Finland
Dysthymia
4.8
12.5
29
64
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
9.4
12.4
25
28
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
4.6
12.3
30
69
G01AA10
ATC
clindamycin; vaginal
2.3
12.3
113
568
N05BA01
ATC
diazepam; systemic, rectal
2.8
12.3
66
257
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
3.8
12.3
39
110
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
4.1
12.2
34
87
P01AB01
ATC
metronidazole; oral, rectal
2.0
12.2
219
1421
G43.9
ICD-10 Finland
Migraine, unspecified
2.8
12.1
67
265
M01AE02
ATC
naproxen; oral, rectal
2.0
12.1
299
2167
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
4.1
12.0
34
88
N92.5
ICD-10 Finland
Other specified irregular menstruation
3.7
12.0
39
112
R51.81
ICD-10 Finland
Facial pain NOS
5.6
11.9
23
43
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
11.7
112
572
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.7
11.7
69
282
R06.0
ICD-10 Finland
Dyspnoea
2.3
11.7
108
544
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
66.6
11.7
13
*
8113
FHL
Fractional scraping
23.6
11.6
16
7
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
10.4
11.6
22
22
N05CF01
ATC
zopiclone; oral
2.1
11.6
135
746
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
4.7
11.6
27
60
D01
ICPC
Abdominal pain/cramps general
2.6
11.5
73
309
UJF32
NOMESCO Finland
Coloscopy
2.4
11.5
86
394
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
4.4
11.4
29
69
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.0
11.4
327
2472
H02AB06
ATC
prednisolone; systemic
1.9
11.3
217
1432
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.7
11.2
63
251
Z2221
NOMESCO Finland
Medical doctor
2.0
11.1
152
889
N89
ICPC
Migraine
3.4
11.1
42
133
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
10.4
11.1
21
21
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
5.0
11.1
24
50
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.5
11.1
39
118
R06AX27
ATC
desloratadine; oral
2.0
11.0
196
1257
M25.5
ICD-10 Finland
Pain in joint
2.0
10.8
177
1102
N03AX11
ATC
topiramate; oral
4.3
10.8
28
68
N03AX16
ATC
[U] pregabalin
2.2
10.7
103
525
LGA21
NOMESCO Finland
Laparoscopic sterilisation by constriction of Fallopian tubes
3.1
10.7
47
163
N06BA04
ATC
methylphenidate; oral
3.4
10.7
40
126
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
61.4
10.7
12
*
J01CA08
ATC
pivmecillinam; oral
1.9
10.5
265
1897
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
+∞
10.5
10
*
A06AC51
ATC
ispaghula, combinations; oral
4.5
10.4
26
61
D19
ICPC
Teeth/gum symptom/complaint
2.0
10.4
166
1021
LCD10
NOMESCO Finland
Vaginal hysterectomy
10.9
10.4
19
18
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.3
10.3
41
134
P06
ICPC
Sleep disturbance
2.5
10.3
71
313
F31.8
ICD-10 Finland
Other bipolar affective disorders
4.8
10.1
23
50
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
10.1
173
1089
N01
ICPC
Headache
2.3
10.0
83
397
G44.2
ICD-10 Finland
Tension-type headache
2.2
10.0
92
460
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
10.0
39
126
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.5
10.0
69
304
N94.1
ICD-10 Finland
Dyspareunia
12.5
9.9
17
14
G03DC03
ATC
lynestrenol; oral
5.3
9.9
20
39
P29
ICPC
Psychological sympt/compl other
2.5
9.9
65
280
1410
FHL
Laparoscopy
11.0
9.9
18
17
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
9.7
174
1108
G03FB08
ATC
dydrogesterone and estrogen; systemic
3.3
9.7
37
118
L03
ICPC
Low back symptom/complaint
2.0
9.7
144
862
J01AA02
ATC
doxycycline; systemic
2.0
9.6
360
2894
LDA10
NOMESCO Finland
Curettage of cervix uteri
3.7
9.5
31
89
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
3.5
9.5
33
99
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
18.0
9.5
14
8
N97.8
ICD-10 Finland
Female infertility of other origin
102.0
9.4
10
*
N80.4
ICD-10 Finland
Endometriosis of rectovaginal septum and vagina
102.0
9.4
10
*
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
4.5
9.4
23
53
N97.1
ICD-10 Finland
Female infertility of tubal origin
+∞
9.4
9
*
M79.1
ICD-10 Finland
Myalgia
2.2
9.4
94
486
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
4.2
9.4
25
62
R00.2
ICD-10 Finland
Palpitations
2.7
9.3
51
200
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
9.2
92
474
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
3.7
9.2
30
86
A01
ICPC
Pain general/multiple sites
2.9
9.2
46
172
M01AE03
ATC
ketoprofen; systemic, rectal
1.9
9.2
152
940
F51.0
ICD-10 Finland
Nonorganic insomnia
2.1
9.2
109
601
K80
ICPC
Cardiac arrhythmia NOS
3.1
9.2
39
133
D11
ICPC
Diarrhoea
2.2
9.1
82
405
M54.5
ICD-10 Finland
Low back pain
1.8
9.1
188
1246
N02BE01
ATC
paracetamol; systemic, rectal
2.4
9.1
416
3551
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.0
9.0
41
145
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
4.3
9.0
23
55
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.4
9.0
64
286
J01EA01
ATC
trimethoprim; systemic
1.9
9.0
141
857
ZYC01
NOMESCO Finland
Remote contact by phone
3.2
8.9
37
124
J31.0
ICD-10 Finland
Chronic rhinitis
2.6
8.9
53
217
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
5.0
8.9
19
39
R03AC02
ATC
salbutamol; inhalant
1.8
8.9
287
2171
F32
ICD-10 Finland
Depressive episode
2.8
8.9
47
181
X02
ICPC
Menstrual pain
4.2
8.9
24
60
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
2.8
8.8
45
170
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.8
8.8
46
176
SAA01
NOMESCO Finland
Simple examination of mouth
2.0
8.8
382
3169
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.6
8.8
29
84
N03AG01
ATC
valproic acid; systemic, rectal
3.0
8.8
40
142
WYA10
NOMESCO Finland
Emergency care or similar visit
2.6
8.7
52
214
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.0
8.6
115
660
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
8.5
97
525
S01
ICPC
Pain/tenderness of skin
4.0
8.5
24
62
K04
ICPC
Palpitations/awareness of heart
3.4
8.5
31
96
M54.4
ICD-10 Finland
Lumbago with sciatica
2.1
8.5
90
475
R03BA05
ATC
fluticasone; inhalant
2.0
8.4
101
558
N95.8
ICD-10 Finland
Other specified menopausal and perimenopausal disorders
+∞
8.4
8
*
TLW12
NOMESCO Finland
Insertion of frozen embryo
+∞
8.4
8
*
F90.0
ICD-10 Finland
Disturbance of activity and attention
3.0
8.3
38
135
Z30.0
ICD-10 Finland
General counselling and advice on contraception
2.2
8.3
72
350
J01DB01
ATC
cefalexin; oral
2.1
8.3
402
3420
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
8.3
92
493
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
8.3
262
1954
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.8
8.2
286
2189
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.7
8.2
45
177
Z71.8
ICD-10 Finland
Other specified counselling
1.8
8.2
165
1080
A06AD11
ATC
lactulose; oral
2.9
8.2
40
148
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
8.1
112
648
M01AH05
ATC
etoricoxib; oral
1.8
8.1
290
2234
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
8.1
70
340
L17
ICPC
Foot/toe symptom/complaint
1.9
8.1
121
720
G04BD12
ATC
mirabegron; oral
3.3
8.1
30
94
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.6
8.0
48
197
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.7
8.0
45
179
X15
ICPC
Vaginal symptom/complaint other
3.0
8.0
36
127
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.3
8.0
30
95
N06AX05
ATC
trazodone; oral
4.2
7.9
21
52
F39
ICD-10 Finland
Unspecified mood [affective] disorder
4.2
7.9
21
52
F45.8
ICD-10 Finland
Other somatoform disorders
2.3
7.9
64
303
N02CC06
ATC
eletriptan; oral
2.9
7.8
37
134
G02CB01
ATC
bromocriptine; systemic
4.3
7.8
20
48
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
3.3
7.8
29
91
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
7.8
169
1127
A01AB09
ATC
miconazole; local oral
2.8
7.7
39
147
N05CF02
ATC
zolpidem; oral
2.0
7.7
90
492
D06
ICPC
Abdominal pain localized other
2.5
7.7
49
208
R01AD09
ATC
mometasone; nasal
1.7
7.6
253
1896
R03BA08
ATC
ciclesonide; inhalant
2.5
7.6
51
222
C09CA06
ATC
candesartan; oral
2.0
7.6
95
532
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.3
7.5
61
288
N06AX22
ATC
agomelatine; oral
4.0
7.5
21
54
UKC02
NOMESCO Finland
Cystoscopy
3.1
7.5
31
104
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.0
7.5
94
526
N76.0
ICD-10 Finland
Acute vaginitis
2.3
7.5
61
289
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.1
7.5
81
430
N64.4
ICD-10 Finland
Mastodynia
3.2
7.4
30
99
1412
FHL
Laparoscopy and sterilization
3.9
7.4
22
59
N64.5
ICD-10 Finland
Other signs and symptoms in breast
3.9
7.4
22
59
R05
ICPC
Cough
1.9
7.4
120
730
M01AB05
ATC
diclofenac; systemic, rectal
1.7
7.4
300
2367
H01CA02
ATC
nafarelin; nasal
7.0
7.4
17
25
A27
ICPC
Fear of other disease NOS
3.4
7.3
26
79
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.5
7.3
48
206
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.0
7.3
32
111
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
+∞
7.3
7
*
N02CC03
ATC
zolmitriptan; nasal, oral
2.5
7.3
46
194
M01AX17
ATC
nimesulide; oral
2.1
7.3
74
383
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
7.3
84
456
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.2
7.3
28
90
K58
ICD-10 Finland
Irritable bowel syndrome
3.7
7.2
23
65
G43.3
ICD-10 Finland
Complicated migraine
4.0
7.2
20
51
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.5
7.2
45
189
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.2
7.2
29
96
R07.0
ICD-10 Finland
Pain in throat
2.5
7.2
47
202
L14
ICPC
Leg/thigh symptom/complaint
2.8
7.2
37
141
J02AC02
ATC
itraconazole; systemic
2.0
7.2
89
496
F43.1
ICD-10 Finland
Post-traumatic stress disorder
3.0
7.1
31
107
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.1
7.1
68
343
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
4.2
7.1
19
47
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
6.2
7.1
18
30
C03CA01
ATC
furosemide; systemic
2.3
7.1
56
261
Z2445
NOMESCO Finland
Psychologist
3.1
7.1
30
102
UJF30
NOMESCO Finland
Ileoscopy through colon
2.5
7.1
44
184
R60.9
ICD-10 Finland
Oedema, unspecified
3.5
7.1
24
71
H53.1
ICD-10 Finland
Subjective visual disturbances
2.7
7.1
38
148
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.6
7.0
40
160
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
7.0
190
1339
G01AF05
ATC
econazole; vaginal
2.3
7.0
58
276
SPAT1263
SPAT
Sampling
1.7
7.0
193
1366
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
7.0
143
933
G43
ICD-10 Finland
Migraine
2.3
7.0
55
257
G03GA01
ATC
chorionic gonadotrophin; parenteral
3.7
6.9
22
62
SPAT1104
SPAT
Monitoring of emergency patient
3.3
6.9
26
82
SPAT1240
SPAT
Therapeutic discussion
2.0
6.9
78
419
J05AB01
ATC
aciclovir; systemic
1.8
6.9
111
673
N04BC05
ATC
pramipexole; oral
3.1
6.9
28
93
LCA10
NOMESCO Finland
Curettage of body of uterus
8.4
6.9
14
17
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
8.4
6.9
14
17
R01AD58
ATC
fluticasone, combinations; nasal
1.7
6.9
159
1073
J45
ICD-10 Finland
Asthma
2.2
6.8
59
286
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
6.8
250
1903
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.8
6.8
34
127
L01
ICPC
Neck symptom/complaint
2.0
6.8
84
466
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
5.8
6.8
18
32
H13
ICPC
Plugged feeling ear
2.2
6.8
62
307
SPAT1260
SPAT
Consultation of another employee
2.1
6.8
72
378
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.4
6.8
17
40
KMAK, ,
NOMESCO Finland
1.7
6.8
291
2305
A02BC04
ATC
rabeprazole; oral
2.4
6.8
47
207
LAC01
NOMESCO Finland
Laparoscopic excision of ovarian cyst
17.0
6.8
10
6
D25.1
ICD-10 Finland
Intramural leiomyoma of uterus
2.9
6.7
31
111
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.7
6.7
35
134
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
4.1
6.7
18
45
C07AB02
ATC
metoprolol; systemic
2.3
6.7
54
255
L20
ICPC
Joint symptom/complaint NOS
3.4
6.6
24
74
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.1
6.5
64
326
E0000UV, ,
ATC
1.7
6.5
200
1450
G54.0
ICD-10 Finland
Brachial plexus disorders
3.6
6.5
21
60
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.9
6.5
85
481
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
4.0
6.5
18
46
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
6.5
192
1379
U02
ICPC
Urinary frequency/urgency
2.1
6.5
66
342
LBE20
NOMESCO Finland
Laparoscopic bilateral salpingectomy
7.6
6.5
14
19
N02CC04
ATC
rizatriptan; oral
2.3
6.4
52
245
N85.0
ICD-10 Finland
Endometrial glandular hyperplasia
70.8
6.4
7
*
TLW10
NOMESCO Finland
Transfer of fresh embryo
70.8
6.4
7
*
Z00.8
ICD-10 Finland
Other general examinations
2.4
6.4
44
193
N39.3
ICD-10 Finland
Stress incontinence
2.8
6.4
31
114
3007
Kela drug reimbursment
Erenumab and fremanezumab
4.2
6.4
17
42
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.1
6.4
27
92
A05
ICPC
Feeling ill
2.6
6.4
38
156
R03AC13
ATC
formoterol; inhalant
3.4
6.4
23
71
IGY02
NOMESCO Finland
Psychiatric monitoring contact
3.4
6.4
22
66
R06AX22
ATC
ebastine; oral
1.8
6.3
105
642
R30.0
ICD-10 Finland
Dysuria
3.2
6.3
25
82
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
18.3
6.3
9
5
L86
ICPC
Back syndrome with radiating pain
2.9
6.3
29
104
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
6.3
134
881
6262A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Excessive or frequent menstruation[HYPERMENORRHOEA]
+∞
6.3
6
*
N80.8
ICD-10 Finland
Other endometriosis
+∞
6.3
6
*
S29
ICPC
Skin symptom/complaint other
2.0
6.2
77
427
K59.09
ICD-10 Finland
Constipation, unspecified
3.6
6.2
20
57
J01CA04
ATC
amoxicillin; systemic
1.9
6.2
404
3543
H03AA01
ATC
levothyroxine sodium; systemic
1.8
6.2
117
742
N02CC05
ATC
almotriptan; oral
2.5
6.2
38
158
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
7.8
6.2
13
17
Z01.2
ICD-10 Finland
Dental examination
1.6
6.1
237
1811
J01MA02
ATC
ciprofloxacin; systemic
1.7
6.1
134
887
D06BB10
ATC
imiquimod; topical
3.0
6.1
26
89
R21
ICPC
Throat symptom/complaint
1.7
6.1
142
955
M54.2
ICD-10 Finland
Cervicalgia
2.3
6.1
46
211
X11
ICPC
Menopausal symptom/complaint
6.8
6.1
14
21
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
6.1
104
641
M54.1
ICD-10 Finland
Radiculopathy
3.4
6.1
21
63
SPAT1307
SPAT
Psychosocial counselling and guidance
2.2
6.1
50
238
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
6.1
185
1334
M01AG02
ATC
tolfenamic acid; oral, rectal
1.8
6.0
96
578
E61.1
ICD-10 Finland
Iron deficiency
3.1
6.0
25
84
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.3
6.0
45
205
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
3.1
6.0
24
79

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
115
301
4.72
41.58
1.5
1.3
13.18
24.84
iu/l
4.85
101
263
44
76
6.28
24.92
1.3
1.3
8.88
12.83
u/l
0.79
35
60
201
1049
2.59
21.93
1.9
1.7
102.16
97.77
pmol/l
0.55
110
565
419
3198
3.59
19.97
6.0
4.0
14.23
14.28
pmol/l
0.19
407
2990
306
2026
2.43
18.82
3.7
2.7
57.91
65.37
ug/l
1.19
300
1930
450
3690
5.02
17.26
7.0
4.5
1.60
1.79
mu/l
4.08
441
3497
280
1844
2.26
16.57
5.1
5.7
1.98
2.01
e9/l
0.25
251
1687
180
991
2.31
16.45
2.7
3.3
2.35
2.34
mmol/l
0.40
165
909
179
984
2.31
16.41
1.4
1.3
1.56
1.83
u/ml
0.12
41
287
270
1760
2.23
16.28
5.2
5.8
0.04
0.04
e9/l
0.23
234
1574
114
514
2.60
16.15
2.3
2.5
116.61
87.16
ug/g
0.29
86
408
147
747
2.40
16.10
2.0
2.0
298.77
143.59
u/l
0.34
141
707
347
2516
2.40
16.08
6.4
6.4
70.43
73.14
u/l
0.76
332
2386
300
2051
2.25
15.95
7.2
9.1
3.84
4.00
e9/l
0.74
269
1832
268
1756
2.20
15.77
5.2
5.8
0.49
0.52
e9/l
2.03
234
1576
235
1473
2.18
15.35
2.7
2.1
77.58
72.41
nmol/l
2.14
223
1381
275
1849
2.15
14.80
5.4
6.1
0.18
0.17
e9/l
0.43
246
1676
326
2344
2.24
14.76
4.7
3.3
1649.40
921.26
e6/l
—
5
19
354
2637
2.34
14.64
4.8
3.5
7.85
9.80
mm/h
5.17
339
2474
35
80
4.64
14.51
1.4
1.3
7.02
28.42
u/l
6.53
24
71
443
3696
3.86
14.29
11.1
8.7
139.41
139.57
mmol/l
0.80
437
3582
89
376
2.68
14.25
1.8
1.6
1121.77
1183.20
nmol/l
0.28
81
289
162
898
2.22
14.18
2.1
2.1
55.06
57.69
u/l
0.49
152
838
253
1670
2.10
14.03
5.5
6.2
—
—
—
0
0
194
1166
2.12
13.73
3.9
4.3
37.04
36.72
g/l
0.40
185
1095
442
3704
3.71
13.69
11.1
8.7
3.90
3.90
mmol/l
0.00
434
3579
86
368
2.63
13.38
1.2
1.2
—
—
—
0
0
259
1751
2.05
13.16
5.0
5.5
57.43
56.68
%
0.59
254
1659
152
845
2.17
13.04
1.4
1.3
1.97
2.09
g/l
0.64
88
555
333
2478
2.14
12.93
4.6
3.5
—
—
—
0
0
80
339
2.63
12.66
1.8
2.2
338.85
381.96
nmol/l
1.53
73
315
240
1601
2.01
12.42
5.0
5.8
0.69
0.65
%
0.71
231
1507
131
698
2.21
12.41
3.7
3.0
1.01
1.01
kg/l
0.22
18
106
258
1767
2.00
12.37
5.1
5.6
29.40
29.79
%
0.29
251
1680
247
1669
2.00
12.28
5.0
5.7
2.70
2.67
%
0.07
239
1580
111
558
2.29
12.07
1.5
1.3
380.95
638.61
titre
0.94
21
115
107
533
2.30
11.88
1.6
1.5
—
—
—
0
0
247
1682
1.97
11.87
5.3
5.9
7.27
7.77
%
2.28
241
1596
212
1382
1.96
11.46
2.0
1.7
—
—
—
0
0
22
42
5.44
11.16
1.4
1.4
—
—
—
0
0
450
3917
3.72
10.93
11.4
9.0
15.57
19.08
mg/l
2.01
357
2916
350
2737
2.05
10.77
3.3
2.5
31.61
34.04
u/l
0.30
343
2613
59
236
2.71
10.40
1.2
1.2
—
—
—
0
0
384
3124
2.19
10.40
4.7
3.7
36.81
37.54
mmol/mol
1.01
362
2956
70
307
2.50
10.24
1.3
1.3
—
—
—
0
0
35
104
3.55
10.21
1.6
2.9
—
—
—
0
0
207
1383
1.88
10.03
3.2
2.6
6.18
5.88
ph
0.52
19
130
223
1546
1.83
9.44
4.1
5.4
8.91
10.01
umol/l
1.37
211
1458
414
3517
2.36
9.35
4.3
3.1
5.50
5.59
mmol/l
1.10
398
3293
247
1770
1.82
9.35
3.4
4.0
6.23
6.30
mmol/l
0.20
223
1580
203
1373
1.83
9.27
5.9
5.7
1.23
1.22
mmol/l
1.94
185
1169
458
4108
4.04
8.98
10.1
7.8
24.25
23.68
u/l
0.27
449
3989
242
1743
1.79
8.84
3.3
2.8
0.00
0.01
estimate
0.50
43
368
183
1213
1.83
8.82
4.9
4.9
1.23
1.22
mmol/l
1.92
174
1131
46
176
2.79
8.81
1.9
3.1
—
—
—
0
0
88
458
2.13
8.59
2.7
2.3
2.42
2.41
mmol/l
0.12
76
397
129
776
1.91
8.38
2.4
1.9
2.67
2.61
mg/l
0.07
112
679
284
2169
1.77
8.25
2.9
2.5
—
—
—
0
0
66
311
2.30
8.20
1.4
1.4
—
—
—
0
0
116
687
1.91
7.85
1.5
1.3
13.44
11.04
u/ml
0.10
33
285
236
1731
1.72
7.74
4.6
3.9
0.00
0.00
estimate
-0.00
39
352
142
901
1.82
7.72
2.5
2.3
10.10
20.84
ng/l
2.16
52
380
97
545
1.98
7.64
1.3
1.4
21.73
20.24
nmol/l
0.56
86
491
122
743
1.86
7.54
1.5
1.3
23.17
20.81
iu/ml
0.10
39
233
164
1095
1.76
7.46
2.9
2.9
94.29
71.13
e6/l
0.19
109
687
41
162
2.68
7.40
1.6
1.3
—
—
—
0
0
68
344
2.14
7.09
1.3
1.1
—
—
—
0
0
49
216
2.41
7.06
1.0
1.1
—
157.78
—
0
9
51
229
2.37
7.06
1.8
2.1
—
—
—
0
0
235
1752
1.67
7.02
3.5
2.8
0.00
0.00
estimate
-0.00
39
354
98
572
1.90
6.86
1.8
1.6
434.36
56589581.57
pmol/l
1.34
92
516
71
370
2.08
6.85
2.3
2.2
2.42
2.49
g/l
0.44
66
346
66
338
2.11
6.66
2.3
2.3
24.61
23.83
%
0.20
58
289
45
198
2.41
6.52
1.6
2.1
—
—
—
0
0
63
320
2.12
6.49
1.2
1.2
84.04
247.79
u/ml
1.42
56
297
126
808
1.76
6.46
1.6
1.5
0.51
0.76
mg/l
2.44
83
584
128
825
1.75
6.45
3.1
3.3
7.40
7.40
ph
0.40
17
163
461
4259
3.62
6.39
11.6
8.4
—
—
—
0
0
23
72
3.31
6.23
1.2
1.3
337.75
356.41
ug/g
0.13
12
35
71
384
2.00
6.18
1.3
1.2
90.99
156.11
iu/ml
0.71
27
163
109
679
1.79
6.14
3.3
2.5
—
—
—
0
0
156
1079
1.66
6.01
6.7
6.3
1.08
1.07
inr
0.07
45
370
52
254
2.18
5.92
1.8
2.0
—
—
—
0
0
52
256
2.16
5.80
1.8
2.0
—
—
—
0
0
51
250
2.16
5.75
1.8
2.0
—
—
—
0
0
52
257
2.15
5.75
1.8
2.0
—
—
—
0
0
156
1092
1.64
5.68
1.6
1.6
—
—
—
0
0
399
3514
1.84
5.65
14.1
11.6
14.42
14.14
%
0.46
399
3450
423
3797
2.02
5.64
4.2
3.3
2.94
2.95
mmol/l
0.02
410
3617
39
172
2.38
5.63
1.5
1.7
—
—
—
0
0
219
1666
1.58
5.63
2.3
2.3
—
—
—
0
0
137
931
1.66
5.59
2.2
2.2
—
—
—
0
0
172
1238
1.61
5.57
3.2
2.9
25.93
27.02
u/l
0.38
161
1189
28
106
2.74
5.51
1.2
1.1
—
—
—
0
0
55
283
2.07
5.48
2.0
2.1
39.83
41.23
u/l
0.04
47
243
418
3757
1.92
5.25
4.0
3.1
4.85
4.88
mmol/l
0.33
405
3587
24
86
2.89
5.22
1.0
1.1
—
—
—
0
0
24
86
2.89
5.22
1.0
1.1
—
—
—
0
0
176
1291
1.58
5.19
2.2
1.9
—
—
—
0
0
33
141
2.44
5.11
1.1
1.1
3.38
5.62
u/ml
—
5
32
107
698
1.69
5.05
2.0
2.1
282.29
2422.73
umol/l
1.34
93
639
42
201
2.19
5.04
1.2
1.2
—
—
—
0
0
15
41
3.75
4.96
1.3
1.2
—
—
—
0
0
144
1021
1.59
4.86
1.8
1.8
—
—
—
0
0
400
3569
1.76
4.85
3.6
2.8
1.18
1.17
mmol/l
0.09
387
3392
86
537
1.73
4.74
2.4
2.5
489.75
521.72
mosm/kgh2o
0.58
71
463
71
419
1.82
4.74
3.2
3.4
0.82
0.83
mmol/l
0.43
66
400
16
50
3.28
4.37
1.6
1.4
—
—
—
0
0
413
3748
1.77
4.33
3.9
3.1
1.54
1.56
mmol/l
0.41
401
3581
73
446
1.75
4.33
3.2
2.6
1521.36
431.51
ng/l
0.32
39
215
45
235
2.01
4.33
4.4
3.3
—
—
—
0
0
115
795
1.59
4.25
2.7
2.5
—
—
—
0
0
44
231
2.00
4.17
3.6
4.4
0.00
1.57
%
—
8
51
48
260
1.94
4.17
1.4
1.3
—
27.95
—
0
19
49
268
1.92
4.14
1.7
2.0
4.22
5.63
e9/l
0.61
44
244
109
751
1.59
4.08
3.6
2.9
—
—
—
0
0
121
855
1.56
4.06
2.7
2.6
51.65
150.06
e6/l
0.64
93
630
205
1621
1.46
3.99
7.7
7.6
0.00
0.00
e9/l
0.17
171
1340
44
236
1.95
3.94
3.9
4.3
0.11
0.05
%
—
9
55
49
274
1.88
3.88
5.3
6.0
1.05
1.04
mmol/l
0.15
42
259
12
28
4.37
3.84
1.2
1.5
6.18
5.47
ug/l
0.20
12
21
87
577
1.62
3.80
2.2
2.3
5.93
9.16
e6/l
2.06
76
508
7
8
8.86
3.78
2.7
5.3
10.39
20.44
umol/l
—
7
8
19
72
2.71
3.77
1.2
1.2
—
—
—
0
0
32
155
2.14
3.76
1.1
1.1
—
—
—
0
0
42
227
1.93
3.69
1.7
1.2
—
—
—
0
0
111
785
1.54
3.68
2.9
3.3
7.06
7.70
mmol/l
0.65
90
696
24
104
2.38
3.65
1.1
1.2
—
—
—
0
0
37
192
2.01
3.64
4.6
3.3
—
—
—
0
0
9
17
5.37
3.52
4.4
3.2
37600.00
41735.29
ug/l
—
9
17
45
254
1.85
3.48
3.8
4.1
0.70
0.78
%
—
10
73
58
355
1.72
3.43
1.9
1.9
1121.56
5285.23
u/l
2.18
18
138
42
233
1.88
3.42
3.2
3.9
0.18
0.70
%
1.76
11
61
59
365
1.70
3.36
1.4
1.3
—
—
—
0
0
20
83
2.47
3.35
1.1
1.2
—
—
—
0
0
121
889
1.48
3.32
6.0
6.8
—
—
—
0
0
37
201
1.91
3.22
1.2
1.1
—
—
—
0
0
60
381
1.66
3.11
1.2
1.2
—
—
—
0
0
23
106
2.23
3.08
1.6
1.2
46.40
3.16
u/ml
—
5
19
62
399
1.64
3.05
1.7
1.7
—
—
—
0
0
23
107
2.21
3.01
2.4
2.0
—
—
—
0
0
26
129
2.07
2.92
2.4
2.8
104.29
92.84
ng/l
0.16
21
108
56
358
1.64
2.84
1.3
1.4
—
—
—
0
0
17
71
2.45
2.83
1.2
1.5
85.20
119.50
u/ml
—
5
18
11
33
3.39
2.83
1.0
1.2
—
—
—
0
0
22
104
2.17
2.79
1.0
1.1
1.83
4.60
u/ml
—
9
54
59
386
1.60
2.73
1.6
1.3
—
—
—
0
0
28
147
1.96
2.71
1.5
1.7
—
—
—
0
0
133
1030
1.40
2.71
2.7
2.5
—
—
—
0
0
23
114
2.07
2.60
6.6
6.5
—
—
—
0
0
118
901
1.41
2.60
3.9
3.2
0.00
0.00
estimate
-0.00
36
350
8
20
4.05
2.57
1.0
1.1
—
—
—
0
0
23
115
2.05
2.55
2.3
2.4
6.85
5.02
umol/l
0.61
13
87
17
75
2.31
2.54
1.4
1.5
—
—
—
0
0
104
782
1.42
2.49
2.8
2.6
0.17
0.42
e6/l
1.82
77
570
7
16
4.42
2.48
1.0
1.1
—
12.24
—
0
5
18
83
2.21
2.44
1.1
1.2
—
—
—
0
0
61
417
1.53
2.35
2.1
2.3
2.99
4.07
e6/l
0.52
34
208
9
28
3.26
2.32
2.0
1.3
1.39
1.29
e9/l
—
9
28
37
225
1.70
2.29
3.0
1.9
—
—
—
0
0
20
100
2.04
2.24
1.0
1.1
0.38
0.44
u/ml
—
10
42
7
19
3.72
2.16
1.9
1.3
0.07
0.24
e9/l
—
7
19
7
19
3.72
2.16
1.9
1.2
0.17
0.22
e9/l
—
7
19
78
572
1.43
2.14
2.2
2.1
—
—
—
0
0
25
138
1.86
2.13
3.4
2.7
5.27
4.87
kpa
0.26
25
130
23
124
1.90
2.11
1.0
1.1
6.14
3.14
u/ml
—
10
64
8
25
3.24
2.10
1.6
1.2
—
—
—
0
0
9
31
2.94
2.08
11.4
10.8
0.82
0.65
mmol/l
—
9
26
7
20
3.54
2.06
1.9
1.3
515.43
441.45
e6/l
—
7
20
24
133
1.85
2.03
2.3
1.9
3.00
4.28
iu/l
—
8
60
7
21
3.37
1.97
1.0
1.1
—
—
—
0
0
9
33
2.76
1.94
2.3
1.7
—
—
—
0
0
7
22
3.21
1.88
1.9
1.5
907.00
704.73
e6/l
—
7
22
8
28
2.89
1.87
1.5
1.0
—
—
—
0
0
7
23
3.07
1.80
1.0
1.1
—
—
—
0
0
8
29
2.79
1.80
1.3
1.3
—
—
nmol/l
—
0
0
29
178
1.67
1.77
3.7
3.7
6.02
5.80
kpa
0.56
29
170
8
30
2.69
1.73
1.4
1.2
—
—
—
0
0
26
156
1.71
1.73
7.7
7.5
—
—
—
0
0
17
89
1.94
1.72
5.6
3.3
0.38
0.34
g/l
—
7
35
5
13
3.87
1.72
1.6
2.7
—
—
—
0
0
56
403
1.44
1.72
1.8
1.7
—
—
—
0
0
10
40
2.53
1.67
1.5
1.9
—
—
—
0
0
6
19
3.18
1.66
2.3
1.3
79.67
73.74
%
—
6
19
6
19
3.18
1.66
2.3
1.3
11.00
13.74
%
—
6
19
8
31
2.61
1.66
1.5
1.5
—
—
—
0
0
5
14
3.60
1.62
3.4
2.6
—
—
—
0
0
5
14
3.60
1.62
1.4
1.3
14.80
13.08
pmol/l
—
5
14
8
33
2.45
1.54
1.3
1.2
0.46
0.50
nmol/l
—
8
33
7
28
2.52
1.45
1.1
1.1
—
—
—
0
0
6
22
2.75
1.44
2.0
1.9
48.60
46.00
%
—
6
22
9
39
2.33
1.43
1.0
1.4
—
—
—
0
0
39
275
1.46
1.36
1.4
1.3
316.28
237.24
miu/ml
0.52
21
147
16
90
1.80
1.34
2.0
2.2
—
—
—
0
0
5
19
2.65
1.22
2.2
2.0
—
—
—
0
0
14
79
1.80
1.18
3.0
2.6
0.69
0.66
%
0.12
14
79
20
126
1.61
1.16
1.0
1.2
—
—
—
0
0
0
34
0.00
1.16
0.0
2.1
—
—
—
0
0
17
105
1.64
1.07
1.1
1.1
1.80
1.59
u/ml
—
9
41
7
33
2.14
1.06
1.1
1.2
—
—
—
0
0
9
51
1.78
0.95
1.1
1.7
—
—
—
0
0
7
37
1.90
0.94
1.0
1.1
—
—
—
0
0
10
55
1.84
0.92
2.5
2.2
—
—
—
0
0
47
369
1.30
0.91
1.7
2.1
3.80
5.35
umol/l
1.20
41
307
6
31
1.95
0.84
1.2
1.2
—
—
—
0
0
82
697
1.21
0.83
1.6
1.5
—
—
—
0
0
8
46
1.75
0.83
2.5
2.6
—
—
—
0
0
47
375
1.28
0.82
1.4
1.3
—
—
—
0
0
8
47
1.71
0.81
1.0
1.4
—
—
—
0
0
19
131
1.47
0.79
2.2
2.1
—
—
—
0
0
0
27
0.00
0.77
0.0
1.3
—
—
—
0
0
5
24
2.09
0.74
1.0
1.0
1551.60
1781.87
miu/ml
—
5
24
7
40
1.76
0.71
1.0
2.0
8.63
8.21
kpa
—
7
40
9
57
1.59
0.71
1.0
1.0
—
—
—
0
0
23
169
1.38
0.71
1.3
1.2
—
—
—
0
0
5
26
1.93
0.71
2.8
1.6
—
—
—
0
0
13
85
1.54
0.69
3.8
2.6
—
—
—
0
0
175
1612
1.14
0.65
2.2
2.1
—
—
—
0
0
5
29
1.73
0.64
2.2
1.8
65.60
72.61
mmol/l
—
5
23
8
49
1.64
0.62
1.3
1.8
—
—
—
0
0
30
236
1.29
0.61
6.6
6.3
103.67
104.86
mmol/l
0.75
30
236
0
20
0.00
0.60
0.0
2.6
—
663.93
—
0
14
0
20
0.00
0.60
0.0
2.1
—
11.33
—
0
20
33
264
1.27
0.60
1.4
1.4
—
—
—
0
0
33
264
1.27
0.60
1.4
1.4
—
—
—
0
0
10
64
1.57
0.59
1.0
1.0
—
—
—
0
0
34
274
1.26
0.58
1.5
1.5
—
—
—
0
0
97
869
1.15
0.55
1.7
1.6
1.34
1.32
mmol/l
0.09
85
779
55
637
0.85
0.53
1.3
1.2
—
—
—
0
0
13
91
1.44
0.53
3.8
1.9
—
—
—
0
0
6
39
1.55
0.53
1.8
1.4
—
—
—
0
0
103
930
1.14
0.52
1.6
1.7
—
—
—
0
0
9
64
1.41
0.51
4.4
5.6
—
—
—
0
0
20
155
1.30
0.47
1.2
2.7
69.17
67.95
g/l
0.40
20
146
12
85
1.42
0.47
4.9
11.5
1.63
1.61
%
0.02
12
78
7
49
1.43
0.46
1.0
2.1
—
—
—
0
0
13
95
1.38
0.44
1.0
1.1
2.24
4.03
u/ml
—
7
38
73
655
1.14
0.42
3.8
4.0
6.91
13.05
mg/mmol
0.70
38
412
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
5
34
1.48
0.40
1.2
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
2.4
—
500.23
—
0
13
8
61
1.32
0.39
1.3
1.3
—
—
—
0
0
139
1306
1.09
0.35
1.6
1.7
—
—
—
0
0
10
73
1.38
0.34
1.0
1.0
—
—
—
0
0
6
45
1.34
0.34
1.0
1.4
—
—
—
0
0
6
46
1.31
0.33
1.3
2.1
27.50
31.07
umol/l
—
6
40
70
638
1.11
0.33
3.6
3.4
30.48
357.01
mg/l
1.27
38
407
14
112
1.26
0.28
2.0
1.9
2.56
6.33
ug/l
—
9
96
8
67
1.20
0.26
2.5
2.5
—
—
—
0
0
11
87
1.27
0.24
5.3
11.5
0.88
0.93
%
0.20
11
79
10
126
0.79
0.24
1.2
1.2
—
—
—
0
0
10
79
1.27
0.22
1.3
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.01
—
0
12
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
11
89
1.24
0.21
1.0
1.0
—
11.74
—
0
8
6
52
1.16
0.19
2.3
5.3
3.65
3.79
mmol/l
—
6
52
9
80
1.13
0.15
1.2
1.8
—
—
—
0
0
10
84
1.19
0.14
1.4
1.2
17.60
6.21
u/ml
—
5
28
13
113
1.15
0.13
12.6
12.9
—
—
—
0
0
64
611
1.05
0.12
3.8
3.6
—
—
—
0
0
13
115
1.13
0.10
10.7
8.5
0.86
0.69
%
0.45
13
115
11
96
1.15
0.10
1.2
1.1
—
—
—
0
0
5
45
1.11
0.10
2.2
4.5
—
—
—
0
0
5
45
1.11
0.10
1.4
1.8
—
—
—
0
0
6
54
1.11
0.09
1.2
2.5
7.41
7.42
ph
—
6
49
11
122
0.90
0.07
6.3
12.3
25.15
24.78
mmol/l
0.14
11
116
20
188
1.07
0.05
9.4
10.4
119.15
120.48
g/l
0.11
20
183
10
90
1.11
0.05
2.1
1.7
10.35
11.05
mg/l
—
10
85
11
120
0.91
0.05
5.3
10.1
—
—
—
0
0
24
231
1.04
0.03
8.0
9.1
1.29
1.09
mmol/l
0.09
18
180
25
257
0.97
0.01
1.2
1.3
—
—
—
0
0
34
333
1.02
0.01
2.7
3.0
—
—
—
0
0
12
114
1.05
0.00
11.5
8.5
1.16
1.26
%
0.18
12
114
12
125
0.96
0.00
1.3
2.5
—
—
—
0
0
5
54
0.93
0.00
8.2
16.8
103.80
105.22
mmol/l
—
5
49
5
53
0.94
0.00
8.2
17.1
10.60
10.98
mmol/l
—
5
48
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
62.75
—
0
8
7
78
0.90
-0.00
3.1
4.1
54.86
56.26
%
—
7
78
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
61.17
—
0
6
0
8
0.00
-0.00
0.0
4.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.9
—
1.22
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
70.80
—
0
5
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
—
—
0
0
7
76
0.92
-0.00
3.1
4.1
3.39
4.02
e9/l
—
7
76

Mortality – FinRegistry

↥

Association

Association between endpoint N14_PREMENSTSYNDROM and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_PREMENSTSYNDROM.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: N14_PREMENSTSYNDROM – Premenstrual syndrome

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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