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This is a non-core endpoint: only basic statistics are computed.

Exposure to other and unspecified forces of nature

VWXY20_EXPOS_OTHER_UNSPE_FORCES_NATURE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 X39
  • Cause of death: ICD-10 X39

2 out of 7 registries used, show all original rules.

193

4. Check minimum number of events

None

193

5. Include endpoints

None

193

6. Filter based on genotype QC (FinnGen only)

193

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
X30-X39

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 193 114 79
Unadjusted period prevalence (%) 0.04 0.04 0.03
Median age at first event (years) 51.02 43.57 61.77

-FinnGen-

Age distribution of first events

02030405060708090051015202530AgeIndividuals

-FinnGen-

Year distribution of first events

19701975198019851990199520052010201520202023010203040506070YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
166
Matched controls
1662
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
X39
ICD-10 Finland
Exposure to other and unspecified forces of nature
+∞
236.9
165
*
T78.4
ICD-10 Finland
Allergy, unspecified
14.9
25.1
43
38
C01CA24
ATC
epinephrine; parenteral
8.9
18.0
40
57
X59
ICD-10 Finland
Exposure to unspecified factor
4.2
12.9
56
178
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
18.8
11.5
17
10
T78.3
ICD-10 Finland
Angioneurotic oedema
19.5
11.0
16
9
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.1
10.3
44
135
XQ800
NOMESCO Finland
Prick test
5.3
9.2
28
61
X58
ICD-10 Finland
Exposure to other specified factors
3.7
8.8
41
135
T34.8
ICD-10 Finland
Frostbite with tissue necrosis of ankle and foot
+∞
6.3
6
*
ZXA00
NOMESCO Finland
Right side
2.6
6.2
51
242
A92
ICPC
Allergy/allergic reaction NOS
6.8
6.0
14
22

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
104
513
3.23
14.49
6.5
6.0
—
—
—
0
0
81
379
2.96
11.87
5.0
3.9
—
—
—
0
0
123
725
2.92
11.59
7.5
5.8
0.57
0.65
%
0.93
116
684
123
749
2.77
10.48
7.5
5.8
2.80
2.69
%
0.22
117
710
62
267
2.95
10.36
3.6
3.3
245.13
219.81
ng/l
0.08
36
186
123
754
2.74
10.26
7.7
6.0
8.36
8.41
%
0.07
117
721
28
73
4.32
10.09
15.9
9.0
—
—
—
0
0
125
780
2.71
9.94
7.5
5.8
27.90
28.93
%
0.51
119
741
126
790
2.71
9.91
7.1
5.7
0.58
0.57
e9/l
0.20
106
690
129
819
2.73
9.88
7.0
5.7
1.98
1.94
e9/l
0.15
116
731
126
791
2.71
9.87
7.1
5.7
0.04
0.04
e9/l
0.02
106
691
129
822
2.72
9.76
7.4
5.9
0.23
0.18
e9/l
0.68
117
729
122
765
2.62
9.40
7.8
5.6
56.58
56.48
%
0.03
116
729
40
142
3.29
9.22
16.0
8.2
-0.17
0.95
mmol/l
0.90
31
110
104
624
2.45
8.53
10.3
6.2
1.21
1.21
mmol/l
0.25
98
579
74
403
2.36
7.30
7.9
6.7
—
—
—
0
0
31
111
3.14
6.97
19.2
9.0
—
—
—
0
0
29
100
3.24
6.94
2.0
1.3
172.68
156.71
u/ml
0.10
29
90
51
243
2.49
6.69
4.3
2.8
5.33
2.04
e6/l
0.87
24
131
156
1197
2.58
6.48
7.8
7.2
76.38
78.95
u/l
0.46
147
1128
23
72
3.49
6.38
23.2
10.1
0.70
0.67
%
0.15
23
72
45
208
2.52
6.26
1.6
1.4
266.67
400.00
titre
0.58
12
46
23
73
3.44
6.25
23.3
9.5
1.55
1.33
%
0.35
23
73
15
36
4.43
5.94
1.2
1.3
—
—
—
0
0
33
135
2.74
5.84
4.4
5.4
—
—
—
0
0
128
925
2.14
5.79
10.7
9.1
4.35
4.07
e9/l
0.71
109
812
102
684
2.04
5.58
11.3
7.4
1.21
1.21
mmol/l
0.04
95
591
70
412
2.10
5.43
3.0
2.2
726.30
377.63
u/l
0.30
64
390
21
69
3.29
5.41
25.2
10.6
94.61
94.31
%
0.09
21
69
31
128
2.69
5.38
4.4
5.5
0.93
1.52
mmol/l
0.60
24
93
79
488
2.05
5.37
3.3
2.2
—
—
—
0
0
35
154
2.55
5.36
3.8
2.4
47.79
33.55
u/l
0.43
29
130
103
706
1.98
5.17
9.8
8.9
0.00
0.00
e9/l
0.07
81
570
71
430
2.03
5.04
4.8
2.7
—
—
—
0
0
90
596
1.96
4.93
4.3
4.9
34.43
36.08
g/l
1.72
85
569
24
91
2.87
4.87
1.2
1.2
—
—
—
0
0
70
430
1.99
4.72
4.8
2.8
0.33
0.43
e6/l
0.19
47
312
39
195
2.25
4.48
1.3
1.2
—
—
—
0
0
36
175
2.30
4.42
1.6
1.5
—
—
—
0
0
22
84
2.83
4.41
2.8
2.0
—
—
—
0
0
66
407
1.94
4.35
4.4
3.6
7.42
7.40
ph
—
6
77
56
327
2.00
4.31
1.8
1.4
16.88
21.51
nmol/l
1.86
50
286
83
556
1.86
4.23
7.2
7.8
1.43
1.18
inr
0.76
16
169
66
413
1.91
4.13
1.3
1.3
8.69
0.94
u/ml
0.51
13
110
21
81
2.79
4.13
6.0
4.5
—
—
—
0
0
74
481
1.87
4.12
4.9
2.8
70.96
194.80
e6/l
0.41
50
363
145
1165
1.98
4.10
4.9
3.9
14.45
10.33
mm/h
1.72
134
1082
83
565
1.82
3.96
2.5
1.8
95.14
93.00
pmol/l
0.16
50
303
25
108
2.51
3.96
7.2
8.1
23.50
24.69
mmol/l
1.11
25
108
61
377
1.90
3.94
2.4
1.3
3.32
2.29
g/l
0.46
32
233
175
1521
2.61
3.89
28.4
13.5
38.87
40.13
%
1.38
146
1201
13
39
3.50
3.83
1.1
1.1
0.38
1.68
u/ml
—
5
11
137
1092
1.88
3.82
5.1
4.2
—
—
—
0
0
57
350
1.89
3.73
2.0
1.9
2.00
1.17
mg/l
0.63
40
270
7
9
8.02
3.59
1.1
1.3
—
—
—
0
0
67
438
1.81
3.58
3.0
2.7
—
—
—
0
0
35
597
0.49
3.54
2.6
2.6
—
—
—
0
0
34
178
2.10
3.47
2.4
3.9
12.14
7.19
umol/l
0.47
29
153
70
469
1.77
3.42
3.5
2.4
59.35
54.24
u/l
0.33
65
438
56
351
1.84
3.41
2.4
2.0
3.28
2.95
mg/l
0.16
45
312
46
271
1.92
3.39
1.7
1.2
21.23
25.72
iu/ml
0.19
12
86
29
145
2.18
3.32
1.2
1.2
—
—
—
0
0
6
7
8.80
3.28
10.5
8.1
—
—
—
0
0
117
912
1.72
3.28
9.8
4.5
6.57
6.55
mmol/l
0.04
111
834
11
33
3.47
3.24
3.5
2.6
36.20
27.89
mg/l
0.38
11
27
11
33
3.47
3.24
3.4
2.5
48.55
260.69
mg/l
0.57
11
27
16
61
2.77
3.22
1.3
1.4
—
1.96
—
0
5
49
300
1.85
3.20
3.1
2.5
477.41
569.91
mosm/kgh2o
1.90
37
258
36
199
1.99
3.17
2.4
2.2
23.30
23.07
%
0.03
30
175
24
113
2.28
3.16
1.9
1.4
—
—
—
0
0
16
62
2.72
3.13
1.1
1.3
—
—
—
0
0
15
58
2.72
2.95
1.4
1.1
—
—
—
0
0
179
1613
2.51
2.93
23.7
12.6
28.94
22.16
mg/l
1.49
151
1269
13
48
2.83
2.78
2.0
1.5
—
—
—
0
0
15
60
2.63
2.77
1.9
1.5
—
—
—
0
0
63
432
1.68
2.75
1.9
2.0
—
—
—
0
0
43
265
1.80
2.73
1.5
1.3
1.92
10.58
u/ml
—
5
115
56
373
1.71
2.72
2.4
2.8
336.78
7118.46
umol/l
1.71
51
329
6
10
6.15
2.72
1.5
1.0
—
—
—
0
0
9
24
3.88
2.71
4.0
8.7
—
—
—
0
0
53
348
1.72
2.71
3.3
3.3
—
—
—
0
0
12
43
2.91
2.70
4.1
3.4
—
—
—
0
0
23
115
2.14
2.64
1.4
1.3
—
38.76
—
0
9
8
20
4.13
2.59
1.0
1.3
—
—
—
0
0
133
1108
1.64
2.59
4.1
3.3
46.51
44.11
u/l
0.19
125
1065
7
16
4.50
2.50
2.9
10.6
42.57
70.46
%
—
7
16
9
27
3.44
2.42
1.4
1.7
—
—
—
0
0
48
316
1.69
2.41
3.0
2.2
6.28
4.71
e6/l
0.66
40
279
76
562
1.58
2.40
6.3
3.3
164.85
80.30
e6/l
0.26
50
383
5
8
6.38
2.38
1.4
1.0
—
—
—
0
0
67
484
1.59
2.33
1.5
1.6
—
—
—
0
0
11
41
2.78
2.32
1.5
1.3
234.83
335.15
ug/g
—
6
22
162
1438
1.79
2.31
28.6
15.6
332.52
333.12
g/l
0.34
162
1430
6
13
4.73
2.29
1.2
1.2
—
—
—
0
0
59
416
1.60
2.26
1.8
1.6
1.33
1.37
mmol/l
0.16
50
362
31
183
1.83
2.25
1.4
1.3
—
—
—
0
0
5
9
5.67
2.22
1.2
1.0
—
—
—
0
0
183
1697
2.51
2.22
24.8
13.9
73.38
74.28
umol/l
0.20
183
1697
94
745
1.51
2.11
3.1
2.7
99.06
95.11
ug/l
0.11
86
703
9
31
2.99
2.10
2.1
1.8
—
—
—
0
0
14
63
2.32
2.06
2.4
2.4
—
—
—
0
0
20
106
1.99
1.99
1.6
2.0
3.29
5.59
ug/l
1.58
14
94
122
1030
1.50
1.96
3.6
3.5
—
—
—
0
0
5
11
4.63
1.95
2.6
14.1
7.74
12.24
%
—
5
11
11
46
2.48
1.89
1.7
1.2
—
—
—
0
0
162
1462
1.67
1.87
5.6
4.3
1.92
1.83
mu/l
0.15
153
1346
182
1702
2.22
1.84
18.0
11.8
—
—
—
0
0
5
12
4.25
1.83
1.0
1.0
—
—
—
0
0
35
228
1.65
1.82
2.0
2.2
49.03
108.20
ug/g
1.57
27
179
6
19
3.22
1.67
1.2
1.0
—
—
—
0
0
36
242
1.60
1.66
1.9
1.6
957.75
1160.92
nmol/l
0.69
28
195
20
114
1.84
1.64
2.1
4.0
75.04
73.52
e9/l
0.08
14
91
34
226
1.61
1.64
2.2
1.8
—
—
—
0
0
24
145
1.75
1.63
2.0
1.4
—
—
—
0
0
5
14
3.64
1.62
1.2
1.3
—
—
—
0
0
8
32
2.56
1.61
1.3
1.2
—
—
—
0
0
6
20
3.06
1.59
1.8
1.5
—
—
—
0
0
21
123
1.79
1.58
1.2
1.5
—
—
—
0
0
136
1198
1.46
1.58
4.4
3.8
14.46
14.59
pmol/l
0.23
128
1086
5
15
3.39
1.53
1.4
1.5
4.58
8.05
u/l
—
5
15
6
21
2.91
1.51
1.2
1.4
—
—
—
0
0
31
445
0.64
1.48
3.1
3.1
—
—
—
0
0
9
38
2.43
1.48
1.1
1.2
—
—
—
0
0
17
97
1.83
1.40
3.9
2.2
—
—
—
0
0
6
23
2.66
1.38
1.2
1.1
—
—
—
0
0
21
129
1.70
1.36
2.7
5.3
—
—
—
0
0
5
17
2.99
1.36
4.8
3.4
—
—
—
0
0
5
17
2.99
1.36
1.6
1.4
—
—
—
0
0
10
47
2.19
1.36
1.1
1.2
—
—
—
0
0
0
37
0.00
1.36
0.0
4.8
—
—
—
0
0
0
37
0.00
1.36
0.0
4.7
—
22.45
—
0
22
9
43
2.15
1.32
1.4
1.2
—
55.00
—
0
6
6
24
2.55
1.31
1.0
1.0
—
—
—
0
0
11
55
2.06
1.30
1.5
1.3
—
—
—
0
0
16
96
1.73
1.14
1.4
2.4
1110.33
3480.47
u/l
—
7
34
7
30
2.38
1.13
1.6
2.2
0.82
1.05
g/l
—
7
25
8
40
2.04
1.13
1.1
1.4
—
—
—
0
0
8
40
2.04
1.13
6.6
5.2
1.14
1.48
mmol/l
—
8
40
5
21
2.42
1.09
1.0
1.5
—
—
—
0
0
16
98
1.69
1.07
2.8
3.6
4.33
4.78
pmol/l
1.15
16
85
71
591
1.32
1.03
2.9
3.2
—
—
—
0
0
10
53
1.94
1.03
1.7
1.3
—
—
—
0
0
159
1485
1.40
0.99
4.6
4.1
5.95
5.83
mmol/l
0.34
146
1377
27
368
0.69
0.99
3.3
4.4
—
—
—
0
0
64
528
1.32
0.99
5.8
3.3
37.77
26.35
ng/l
0.27
42
311
0
32
0.00
0.96
0.0
1.4
—
—
—
0
0
23
160
1.50
0.94
1.5
1.3
—
—
—
0
0
5
102
0.48
0.92
1.4
4.5
1.19
1.22
mmol/l
—
5
92
48
384
1.33
0.91
4.0
3.8
—
—
—
0
0
13
203
0.61
0.90
1.1
1.4
—
—
—
0
0
6
29
2.10
0.90
1.2
2.0
—
—
—
0
0
42
330
1.35
0.90
3.3
3.5
1.01
1.02
kg/l
—
6
46
8
46
1.77
0.83
1.6
1.2
—
—
—
0
0
54
450
1.28
0.76
4.6
2.9
6.33
7.98
mmol/l
2.68
46
383
34
266
1.34
0.75
1.8
1.8
—
—
—
0
0
7
39
1.82
0.73
1.7
1.1
—
—
—
0
0
5
25
2.03
0.73
2.0
2.8
—
—
—
0
0
57
482
1.26
0.71
3.2
3.2
2.34
2.35
mmol/l
0.08
46
422
5
26
1.95
0.71
1.0
1.0
—
—
—
0
0
7
43
1.65
0.67
1.1
2.7
2.86
5.39
umol/l
—
7
31
5
28
1.81
0.66
1.2
1.2
—
—
—
0
0
47
392
1.26
0.66
5.7
3.1
688.23
56.92
mg/l
0.50
41
258
12
79
1.55
0.64
1.3
1.5
—
—
—
0
0
25
192
1.35
0.63
1.4
1.2
—
—
—
0
0
162
1547
1.29
0.62
5.2
4.4
2.73
2.78
mmol/l
0.25
151
1451
8
53
1.53
0.59
4.3
2.3
—
—
—
0
0
85
767
1.19
0.56
3.4
3.4
0.00
0.00
estimate
—
8
160
9
132
0.67
0.54
2.9
3.3
—
—
—
0
0
147
1397
1.22
0.53
6.0
5.2
38.78
39.19
mmol/mol
0.24
141
1319
71
634
1.19
0.52
2.4
2.1
—
—
—
0
0
35
416
0.81
0.51
3.3
3.4
0.00
0.00
estimate
—
9
151
159
1525
1.24
0.50
4.7
4.1
4.58
4.64
mmol/l
0.34
152
1438
158
1518
1.23
0.47
4.6
4.1
1.39
1.45
mmol/l
1.15
148
1427
11
77
1.45
0.46
1.4
1.4
—
—
—
0
0
11
77
1.45
0.46
1.4
1.4
—
—
—
0
0
84
771
1.16
0.43
5.2
4.8
0.00
0.00
estimate
—
9
156
85
783
1.15
0.41
3.7
3.4
0.00
0.00
estimate
—
9
152
29
244
1.22
0.39
2.2
2.7
2.45
2.44
mmol/l
0.30
20
211
47
415
1.18
0.39
5.6
3.9
17.23
8.66
mg/mmol
0.43
35
271
9
67
1.36
0.38
2.1
3.6
—
—
—
0
0
14
108
1.32
0.36
1.7
4.6
—
7.40
—
0
6
12
92
1.32
0.32
1.5
1.2
—
—
—
0
0
12
92
1.32
0.32
1.5
1.2
—
—
—
0
0
23
194
1.21
0.31
2.1
2.0
—
—
—
0
0
151
1462
1.15
0.31
4.3
3.7
1.33
1.26
mmol/l
0.52
140
1367
12
93
1.31
0.30
1.5
1.2
—
—
—
0
0
12
93
1.31
0.30
1.5
1.2
—
—
—
0
0
8
108
0.73
0.30
2.5
3.1
—
—
—
0
0
11
85
1.31
0.28
1.6
5.1
—
—
—
0
0
38
340
1.15
0.27
1.6
1.7
—
—
—
0
0
25
287
0.85
0.27
2.6
2.9
0.53
0.73
ug/l
1.20
19
192
10
125
0.79
0.23
1.7
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
0.81
—
0
11
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
5
43
1.17
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
6
48
1.26
0.20
9.0
11.8
—
—
—
0
0
26
232
1.14
0.20
1.6
1.5
—
—
—
0
0
11
90
1.24
0.19
1.0
1.1
—
—
—
0
0
23
208
1.12
0.15
1.4
1.5
—
—
—
0
0
18
161
1.13
0.13
22.9
20.4
—
1.39
—
0
25
10
86
1.17
0.11
1.5
1.2
—
—
—
0
0
8
94
0.84
0.07
1.6
1.2
—
—
—
0
0
12
130
0.92
0.04
1.1
1.3
—
—
—
0
0
13
138
0.94
0.02
3.2
4.3
3.14
93.96
ug/l
0.88
13
110
0
7
0.00
0.00
0.0
7.7
—
—
—
0
0
0
6
0.00
0.00
0.0
3.8
—
57.50
—
0
6
0
5
0.00
0.00
0.0
2.2
—
1830.00
—
0
5
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
52
0.96
0.00
2.2
4.3
8.26
8.91
kpa
—
5
47
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
8
84
0.95
0.00
1.1
1.1
—
—
—
0
0
5
55
0.91
0.00
5.0
5.3
2.04
1.49
mg/l
—
5
50
0
5
0.00
0.00
0.0
4.0
—
9.84
—
0
5
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
7
72
0.97
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
3.90
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
198.32
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
4.9
—
0.94
—
0
7
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
2.44
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
571.40
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: VWXY20_EXPOS_OTHER_UNSPE_FORCES_NATURE – Exposure to other and unspecified forces of nature

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).