Unspecified behavioural syndromes associated with physiological disturbances and physical factors +Physiological and behavioural factors associated with disorders of diseases classified elsewhere

F5_PHYSBEHOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F54
  • Hospital discharge: ICD-9 316
  • Cause of death: ICD-10 F54
  • Cause of death: ICD-9 316

2 out of 7 registries used, show all original rules.

636

4. Check minimum number of events

None

636

5. Include endpoints

None

636

6. Filter based on genotype QC (FinnGen only)

636

Control definitions (FinnGen only)

Control exclude
F5_BEHAVE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4724 2748 1950
Only index persons 4145 2451 1694
Unadjusted period prevalence (%)
Whole population 0.07 0.08 0.05
Only index persons 0.08 0.09 0.06
Median age at first event (years)
Whole population 29.95 34.14 23.70
Only index persons 28.04 32.65 21.36

-FinnGen-

Key figures

All Female Male
Number of individuals 636 414 222
Unadjusted period prevalence (%) 0.13 0.14 0.10
Median age at first event (years) 33.44 33.57 33.20

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
576
Matched controls
5757
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F54
ICD-10 Finland
Psychological and behavioural factors associated with disorders or diseases classified elsewhere
+∞
323.0
511
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
7.7
80.7
219
426
3160A
ICD-9 Finland
Psychic factors associated with diseases classified elsewhere[PSYYK TEKIJÄT ORGAANISTEN SAIRAUKSIEN/OIREIDEN YHTE]
+∞
68.1
64
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
7.7
50.6
127
204
H04AA01
ATC
glucagon; nasal, parenteral
9.9
47.3
100
120
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
7.6
46.1
116
185
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
10.5
42.4
86
95
T89
ICPC
Diabetes insulin dependent
8.3
41.5
97
137
103
Kela drug reimbursment
Diabetes, insulin-treated
4.1
40.8
192
624
A10AE05
ATC
insulin detemir; parenteral
7.5
40.7
102
160
N03AX16
ATC
pregabalin; oral
4.1
39.6
183
583
215
Kela drug reimbursment
Diabetes, non-insulin-treated
4.0
37.7
181
593
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
6.6
36.9
101
179
A10AE04
ATC
insulin glargine; parenteral
6.1
35.0
103
200
N06AX21
ATC
duloxetine; oral
5.1
32.5
111
256
N06AX11
ATC
mirtazapine; oral
3.2
31.2
218
931
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
9.1
31.0
67
82
N03AX12
ATC
gabapentin; oral
4.3
29.9
125
352
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
11.4
29.9
57
55
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.9
28.4
134
420
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.9
26.8
93
216
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.1
26.4
175
707
R4110
NOMESCO Finland
Physiotherapy
2.9
26.0
202
905
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.6
25.8
97
244
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
12.7
25.7
46
39
N05BA04
ATC
oxazepam; oral
3.1
25.2
170
692
N02AX02
ATC
tramadol; systemic, rectal
2.7
24.9
234
1170
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
6.0
24.8
71
131
N05AH04
ATC
quetiapine; oral
3.4
24.5
139
499
C03CA01
ATC
furosemide; systemic
3.3
24.3
140
507
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.9
24.2
84
194
N02AA05
ATC
oxycodone; systemic
4.2
24.2
99
270
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
9.5
24.1
50
57
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
7.5
24.0
58
85
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
8.3
23.9
54
71
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.7
23.8
113
352
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
7.4
23.8
58
86
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
15.4
23.8
39
27
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
23.6
225
1128
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
4.1
23.6
100
282
R51.80
ICD-10 Finland
Headache
3.1
23.2
146
562
N06AB03
ATC
fluoxetine; oral
3.8
22.8
106
324
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
9.4
22.5
47
54
N03AE01
ATC
clonazepam; systemic
6.4
22.5
61
105
H3603, E103
ICD-10 Finland
NA
15.1
22.4
37
26
RD210
NOMESCO Finland
NA
5.5
22.2
68
136
TBW99
NOMESCO Finland
Other minor procedure in endocrine surgery
9.9
22.2
45
49
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
7.2
22.0
54
81
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
21.7
155
647
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
18.3
21.6
33
19
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.9
21.5
153
635
E10
ICD-10 Finland
Type 1 diabetes mellitus
8.6
21.4
47
59
Z01.8
ICD-10 Finland
Other specified special examinations
2.8
21.3
164
716
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
4.7
21.1
75
177
N06AA09
ATC
amitriptyline; systemic
4.4
21.0
81
208
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
20.8
175
803
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.4
20.8
263
1507
A10AA02
ATC
NA
8.3
20.2
45
58
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.8
20.2
150
639
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
5.5
20.1
61
121
R50.9
ICD-10 Finland
Fever, unspecified
3.0
19.9
134
536
J01FF01
ATC
clindamycin; systemic
2.6
19.6
171
800
A10AA01
ATC
NA
8.1
19.5
44
58
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
23.5
19.2
27
12
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
7.5
19.0
45
64
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
6.3
18.6
50
85
R4190
NOMESCO Finland
Nutritional therapy
4.3
18.6
73
190
XCK10
NOMESCO Finland
Photography of fundus of eye
4.0
18.4
78
218
N06AB10
ATC
escitalopram; oral
2.6
18.4
153
693
A03FA01
ATC
metoclopramide; systemic, rectal
2.8
18.3
131
542
N03AX09
ATC
lamotrigine; oral
4.8
18.2
63
145
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
9.8
17.9
36
39
N03AF01
ATC
carbamazepine; oral, rectal
6.0
17.8
50
90
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.7
17.8
63
148
N05BA01
ATC
diazepam; systemic, rectal
3.4
17.7
93
311
N06AX16
ATC
venlafaxine; oral
3.1
17.6
106
389
N06AB04
ATC
citalopram; systemic
2.8
17.5
132
560
L04AA06
ATC
mycophenolic acid; systemic
9.3
17.4
36
41
L28
ICPC
Limited function/disability (L)
3.3
17.3
96
333
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
5.3
17.3
54
111
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
5.1
16.9
54
114
XF400
NOMESCO Finland
ECG with 12 standard connections
2.7
16.8
128
544
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.7
16.8
77
230
ZXA10
NOMESCO Finland
Bilateral
2.6
16.7
138
617
M79.6
ICD-10 Finland
Pain in limb
2.2
16.6
218
1233
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
4.9
16.5
55
121
127
Kela drug reimbursment
Transplant complication
8.5
16.5
36
45
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
11.7
16.4
30
27
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.6
16.3
38
53
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.6
16.2
131
578
CKC12
NOMESCO Finland
Photocoagulation of retina
6.4
16.2
43
72
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.3
16.2
176
909
N03AG01
ATC
valproic acid; systemic, rectal
4.0
15.9
65
176
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
10.2
15.9
31
32
H43.1
ICD-10 Finland
Vitreous haemorrhage
10.2
15.9
31
32
RS221
NOMESCO Finland
NA
7.0
15.8
39
59
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
13.4
15.8
27
21
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
15.7
138
638
R5599
NOMESCO Finland
Other rehabilitation service
6.9
15.7
39
60
F43.29
ICD-10 Finland
Adaptation disorder UNS
6.9
15.7
39
60
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
14.3
15.6
26
19
A02BC02
ATC
pantoprazole; systemic
2.1
15.5
320
2181
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.9
15.4
66
186
H02AB09
ATC
hydrocortisone; systemic
5.3
15.3
47
95
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
15.2
158
795
IBA02
NOMESCO Finland
Evaluation of need for psychiatric rehabilitation
11.3
15.1
28
26
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
15.1
102
403
T90
ICPC
Diabetes non-insulin dependent
2.7
15.1
113
475
-69
ICPC
Other reason for encounter NEC
5.7
15.0
43
80
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.7
14.9
115
491
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
7.8
14.9
34
46
ZXA00
NOMESCO Finland
Right side
2.4
14.7
151
752
N05CF01
ATC
zopiclone; oral
2.3
14.7
157
798
UJF32
NOMESCO Finland
Coloscopy
2.4
14.5
137
651
F50.9
ICD-10 Finland
Eating disorder, unspecified
153.7
14.5
15
*
J01DB01
ATC
cefalexin; oral
2.3
14.5
476
3878
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.9
14.5
94
361
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
14.4
225
1354
F43.21
ICD-10 Finland
Adaptation disorder with prolonged depression
13.9
14.3
24
18
R52.2
ICD-10 Finland
Other chronic pain
6.1
14.3
39
68
A10AE06
ATC
insulin degludec; parenteral
5.3
14.3
44
89
N06AX03
ATC
mianserin; oral
5.8
14.2
40
73
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
14.2
161
839
C08CA01
ATC
amlodipine; oral
2.4
14.1
145
720
A01
ICPC
Pain general/multiple sites
3.8
14.1
62
179
R11
ICD-10 Finland
Nausea and vomiting
3.1
14.0
81
288
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.5
14.0
36
58
R06.0
ICD-10 Finland
Dyspnoea
2.4
14.0
140
686
R4120
NOMESCO Finland
Occupational therapy
3.8
13.9
61
176
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
5.2
13.9
43
88
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
13.5
278
1852
N03AF02
ATC
oxcarbazepine; oral
5.4
13.4
40
78
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.8
13.4
58
165
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.1
13.4
77
273
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.9
13.4
56
155
A04AA01
ATC
ondansetron; systemic, rectal
3.7
13.3
60
177
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
11.3
13.1
24
22
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
4.7
13.0
44
99
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
5.0
13.0
42
90
A02BC01
ATC
omeprazole; systemic
2.2
13.0
156
832
R42
ICD-10 Finland
Dizziness and giddiness
2.5
13.0
112
508
F51.0
ICD-10 Finland
Nonorganic insomnia
2.9
13.0
85
327
N03AX11
ATC
topiramate; oral
5.7
12.9
37
69
Z94.0
ICD-10 Finland
Kidney transplant status
7.8
12.8
29
39
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
4.2
12.8
49
125
UKC02
NOMESCO Finland
Cystoscopy
2.9
12.8
84
324
J01MA02
ATC
ciprofloxacin; systemic
2.1
12.7
188
1096
TK800
NOMESCO Finland
Hemodialysis
8.5
12.7
27
33
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
4.2
12.6
48
122
ZX120
NOMESCO Finland
Intravenous
2.9
12.6
79
295
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
7.1
12.5
30
44
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
4.9
12.4
40
86
F32.01
ICD-10 Finland
Mild depressive episode with somatic syndrome
14.7
12.3
20
14
SPAT1262
SPAT
Handing over of treatment supplies
2.5
12.1
104
469
SAA03
NOMESCO Finland
Extended examination of mouth
1.9
12.1
300
2108
H02AB06
ATC
prednisolone; systemic
1.9
11.9
241
1573
A12AA04
ATC
calcium carbonate; oral
8.7
11.9
25
30
L04AA01
ATC
[U] ciclosporin; systemic
10.8
11.8
22
21
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
7.6
11.8
27
37
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
11.8
114
544
N02BE01
ATC
paracetamol; systemic, rectal
2.0
11.8
441
3573
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.4
11.8
59
189
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.2
11.8
31
52
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
6.0
11.8
32
56
A06AD11
ATC
lactulose; oral
2.9
11.8
73
272
WX002
NOMESCO Finland
Sedation and analgesia
2.3
11.8
116
560
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
16.8
11.7
18
11
Z71.8
ICD-10 Finland
Other specified counselling
2.1
11.7
168
961
XA820
NOMESCO Finland
NA
30.7
11.7
15
5
XA800
NOMESCO Finland
Neuropsychological investigation
3.4
11.7
58
185
R41.0
ICD-10 Finland
Disorientation, unspecified
8.4
11.7
25
31
P01
ICPC
Feeling anxious/nervous/tense
2.4
11.7
106
490
R20.2
ICD-10 Finland
Paraesthesia of skin
3.7
11.7
51
147
RS222
NOMESCO Finland
NA
7.4
11.6
27
38
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
11.6
94
410
N06AB06
ATC
sertraline; oral
2.7
11.6
85
350
R52.1
ICD-10 Finland
Chronic intractable pain
23.5
11.6
16
7
G50.1
ICD-10 Finland
Atypical facial pain
11.4
11.6
21
19
A28
ICPC
Limited function/disability NOS
2.7
11.6
82
332
-1
NOMESCO Finland
NA
1.9
11.6
264
1795
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
11.5
70
258
SPAT1216
SPAT
Assessment of functional ability
2.7
11.4
83
338
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
9.9
11.3
22
23
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
11.3
72
272
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
13.1
11.2
19
15
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
20.5
11.2
16
8
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.4
11.2
40
96
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
7.3
11.2
26
37
C07AB02
ATC
metoprolol; systemic
2.5
11.0
92
408
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.6
11.0
49
144
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
10.9
121
614
R35
ICD-10 Finland
Polyuria
4.0
10.9
44
118
XF600
NOMESCO Finland
Bloodpressure measurement
2.9
10.9
70
265
Z49.1
ICD-10 Finland
Extracorporeal dialysis
9.1
10.9
22
25
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.9
10.8
44
119
X58
ICD-10 Finland
Exposure to other specified factors
2.4
10.8
103
487
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
10.8
126
656
F43.20
ICD-10 Finland
Adaptation disorder with short-term depression
7.8
10.8
24
32
H02AB04
ATC
methylprednisolone; systemic
2.5
10.7
86
373
G47.3
ICD-10 Finland
Sleep apnoea
2.4
10.7
101
477
ZXA05
NOMESCO Finland
Left side
2.1
10.6
131
701
K02.1
ICD-10 Finland
Caries of dentine
1.8
10.6
361
2773
EBA15
NOMESCO Finland
Extraction of large number of teeth
4.7
10.5
35
78
E0000UV
ATC
NA
1.8
10.5
241
1624
A11CC03
ATC
alfacalcidol; systemic
5.5
10.4
30
57
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
5.5
10.4
30
57
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.3
10.4
108
534
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.1
10.4
59
207
J01MA12
ATC
levofloxacin; systemic
2.4
10.4
96
448
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.3
10.4
107
526
N06AA12
ATC
doxepin; systemic
4.8
10.4
34
75
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
3.5
10.4
49
151
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.6
10.3
78
328
R53
ICD-10 Finland
Malaise and fatigue
2.1
10.3
123
647
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
10.3
226
1499
XCK00
NOMESCO Finland
Perimetry
3.5
10.3
47
141
H3600, E103
ICD-10 Finland
NA
7.7
10.3
23
31
AA1AD
NOMESCO Finland
CT of head and brain
2.2
10.2
114
580
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
10.1
184
1140
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
10.1
328
2464
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
10.1
70
280
Z50.1
ICD-10 Finland
Other physical therapy
3.9
10.0
41
112
IGY99
NOMESCO Finland
Other psychiatric treatment contact
4.0
10.0
39
102
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
10.0
76
320
A02BA02
ATC
ranitidine; systemic
2.3
10.0
96
457
C07AB07
ATC
bisoprolol; oral
1.9
10.0
189
1190
A07AA02
ATC
nystatin; oral
3.8
9.9
41
113
RS211
NOMESCO Finland
NA
8.3
9.9
21
26
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
12.5
9.9
17
14
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.6
9.9
75
315
C09AA02
ATC
enalapril; systemic
2.5
9.9
83
368
G43.9
ICD-10 Finland
Migraine, unspecified
3.0
9.8
56
197
K59.1
ICD-10 Finland
Functional diarrhoea
3.8
9.8
41
114
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
5.5
9.8
28
53
G44.2
ICD-10 Finland
Tension-type headache
2.4
9.8
83
371
P25
ICPC
Phase of life problem adult
3.7
9.8
42
120
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.2
9.8
50
164
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.7
9.7
68
273
V03AE03
ATC
lanthanum carbonate; oral
56.0
9.7
11
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
9.6
140
798
H3601, E103
ICD-10 Finland
NA
9.3
9.6
19
21
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
6.8
9.5
23
35
-44
ICPC
Preventive immunization/medic
2.9
9.5
59
220
R55
ICD-10 Finland
Syncope and collapse
2.8
9.5
62
238
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
30.6
9.4
12
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
30.6
9.4
12
*
F45.9
ICD-10 Finland
Somatoform disorder, unspecified
30.6
9.4
12
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.8
9.4
39
108
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.7
9.4
31
69
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
9.4
58
215
A04
ICPC
Weakness/tiredness general
2.3
9.4
92
440
3004A
ICD-9 Finland
Neurotic disorders, Neurotic depression
22.1
9.4
13
6
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
6.6
9.3
23
36
A03FA02
ATC
cisapride; oral, rectal
3.3
9.3
46
147
S70.0
ICD-10 Finland
Contusion of hip
5.6
9.3
26
48
N01
ICPC
Headache
2.1
9.3
114
604
SPAT1229
SPAT
Assessment of need for aid
3.3
9.2
46
148
K07.60
ICD-10 Finland
Snapping jaw
3.3
9.2
46
148
137
Kela drug reimbursment
Uraemia requiring dialysis
7.9
9.2
20
26
A27
ICPC
Fear of other disease NOS
3.9
9.1
36
96
B01AB05
ATC
enoxaparin; parenteral
2.0
9.0
137
788
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.2
9.0
33
82
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.7
9.0
307
2302
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.3
8.9
89
428
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.8
8.9
219
1488
S18
ICPC
Laceration/cut
1.8
8.9
216
1461
K08.80
ICD-10 Finland
Toothache NOS
2.9
8.9
55
204
N30.0
ICD-10 Finland
Acute cystitis
2.2
8.9
91
445
G50.0
ICD-10 Finland
Trigeminal neuralgia
10.9
8.8
16
15
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.8
8.8
36
99
SPAT1252
SPAT
Overall medication plan or its review
3.6
8.8
39
115
J01EA01
ATC
trimethoprim; systemic
1.9
8.8
142
839
H04.10
ICD-10 Finland
Dry eye syndrome
2.8
8.8
58
224
B03XA02
ATC
darbepoetin alfa; parenteral
7.8
8.7
19
25
IGY02
NOMESCO Finland
Psychiatric monitoring contact
3.3
8.6
42
133
A02BC03
ATC
lansoprazole; oral
1.9
8.6
134
776
RS140
NOMESCO Finland
NA
11.8
8.6
15
13
A02BC05
ATC
esomeprazole; systemic
1.8
8.6
191
1256
R07.3
ICD-10 Finland
Other chest pain
2.8
8.6
54
204
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
8.6
64
267
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
8.6
85
411
C02AC05
ATC
moxonidine; oral
5.8
8.5
23
41
N05BA12
ATC
alprazolam; oral
2.7
8.5
58
230
N05CD07
ATC
temazepam; oral
2.8
8.5
53
198
WX882
NOMESCO Finland
High dependency care
3.1
8.5
45
152
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.0
8.5
26
54
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.6
8.5
37
108
N06AB05
ATC
paroxetine; oral
3.4
8.4
39
119
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.8
8.4
27
59
WX110
NOMESCO Finland
Local anesthesy
1.7
8.4
414
3425
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
8.4
102
537
F34.1
ICD-10 Finland
Dysthymia
3.9
8.4
33
88
P76
ICPC
Depressive disorder
2.9
8.4
49
177
B05DA
ATC
Isotonic solutions
8.7
8.4
17
20
K06.18
ICD-10 Finland
Another gingival hyperplasia
11.0
8.3
15
14
Z49.2
ICD-10 Finland
Other dialysis
9.6
8.3
16
17
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.9
8.3
50
184
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
8.3
281
2087
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.7
8.2
58
233
81
HP
Angiography of the heart and coronary arteries
5.0
8.2
25
52
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
8.1
108
590
CL2L4
NOMESCO Finland
Wide-field fundus photography for diabetic retinopathy screening
33.9
8.1
10
*
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
33.9
8.1
10
*
W19
ICD-10 Finland
Unspecified fall
2.5
8.1
65
283
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.3
8.1
81
390
A10AA03
ATC
NA
10.2
8.1
15
15
N18.0
ICD-10 Finland
End-stage renal disease
10.2
8.1
15
15
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
6.0
8.1
21
36
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
22.4
8.0
11
5
N05AF03
ATC
chlorprothixene; systemic
4.9
8.0
25
53
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.5
8.0
64
277
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.2
8.0
29
72
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.5
8.0
63
270
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
6.7
7.9
19
29
N05BA09
ATC
clobazam; oral
7.9
7.9
17
22
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
6.2
7.9
20
33
N05CF02
ATC
zolpidem; oral
2.2
7.8
86
431
H36.00
ICD-10 Finland
Diabetic background retinopathy
11.0
7.8
14
13
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
5.2
7.8
23
46
N03AX14
ATC
levetiracetam; systemic
4.2
7.8
28
69
N06AA06
ATC
trimipramine; systemic
5.4
7.8
22
42
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.9
7.7
45
162
M54.6
ICD-10 Finland
Pain in thoracic spine
3.0
7.7
42
145
KMAK
NOMESCO Finland
NA
1.6
7.7
274
2047
L04AX01
ATC
azathioprine; systemic
3.1
7.7
41
140
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
5.1
7.7
23
47
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.1
7.7
95
504
P29
ICPC
Psychological sympt/compl other
2.6
7.6
56
232
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.4
7.6
26
61
G04BD04
ATC
oxybutynin; oral, transdermal
3.7
7.6
32
91
F41.00
ICD-10 Finland
Moderate panic disorder
5.9
7.6
20
35
F39
ICD-10 Finland
Unspecified mood [affective] disorder
5.9
7.6
20
35
QBA10
NOMESCO Finland
Incision of skin of trunk
9.0
7.6
15
17
B05DB
ATC
Hypertonic solutions
9.0
7.6
15
17
TKC20
NOMESCO Finland
Catheterisation of bladder
3.2
7.6
38
124
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.8
7.6
48
182
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
10.2
7.6
14
14
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
7.6
426
3596
L04AD01
ATC
ciclosporin; systemic
4.5
7.5
25
57
S10
ICPC
Boil/carbuncle
3.4
7.5
35
108
A41.9
ICD-10 Finland
Sepsis, unspecified
3.7
7.5
31
87
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
3.7
7.5
31
87
NG4AA
NOMESCO Finland
Lower leg X-ray examination
4.0
7.5
28
72
XKC03
NOMESCO Finland
Water cystometry
4.7
7.5
24
53
F43.8
ICD-10 Finland
Other reactions to severe stress
4.7
7.5
24
53
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
7.5
112
641
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.7
7.4
48
185
WW200
NOMESCO Finland
Immunization
4.5
7.4
25
58
205
Kela drug reimbursment
Chronic hypertension
2.0
7.4
97
525
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.7
7.4
50
195
N18.8
ICD-10 Finland
Other chronic renal failure
4.8
7.4
23
49
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.7
7.4
48
186
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.1
7.4
27
68
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
7.3
72
345
M01AH01
ATC
celecoxib; oral (coxibs)
2.2
7.3
77
382
TAB00
NOMESCO Finland
Lumbar puncture
3.2
7.3
36
116
K65.0
ICD-10 Finland
Acute peritonitis
9.5
7.3
14
15
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.6
7.3
31
89
F43.9
ICD-10 Finland
Reaction to severe stress, unspecified
4.2
7.3
26
64
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.9
7.3
43
157
E000003
ATC
NA
3.1
7.3
38
128
R33
ICD-10 Finland
Retention of urine
3.1
7.3
38
128
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
7.2
105
592
EBA00
NOMESCO Finland
Extraction of tooth
1.7
7.2
213
1505
M25.5
ICD-10 Finland
Pain in joint
1.8
7.2
154
990
N05BE01
ATC
buspirone; oral
4.9
7.2
22
46
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
3.6
7.2
31
90
WX892
NOMESCO Finland
Monitored bed care
2.8
7.2
46
176
C10AA01
ATC
simvastatin; oral
1.8
7.2
140
875
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.0
7.2
27
70
C09CA06
ATC
candesartan; oral
2.0
7.2
97
532
R52.9
ICD-10 Finland
Pain, unspecified
2.5
7.2
53
221
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.4
7.2
61
273
J01MA14
ATC
moxifloxacin; systemic
2.8
7.2
45
169
196
Kela drug reimbursment
Paricalcitol and cinacalcet
20.3
7.2
10
5
M54.2
ICD-10 Finland
Cervicalgia
2.9
7.1
41
146
C07AA05
ATC
propranolol; systemic
1.9
7.1
111
643
F41.1
ICD-10 Finland
Generalized anxiety disorder
2.7
7.1
46
178
U14
ICPC
Kidney symptom/complaint
10.2
7.1
13
13
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.5
7.0
57
247
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.1
7.0
83
433
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.4
7.0
58
257
H01AC01
ATC
somatropin; parenteral
5.3
7.0
20
39
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.2
7.0
70
340
R03AC02
ATC
salbutamol; inhalant
1.6
7.0
306
2394
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
4.7
7.0
22
48
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
7.7
6.9
15
20
WZA90
NOMESCO Finland
Other doctors statement
1.7
6.9
160
1054
J01DA01
ATC
[U] cefalexin; systemic
1.6
6.9
301
2348
SPAT1234
SPAT
Support of social functional capacity
3.6
6.9
29
83
J02AC01
ATC
fluconazole; systemic
1.6
6.9
207
1464
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
6.9
169
1132
P74
ICPC
Anxiety disorder/anxiety state
3.1
6.9
36
122
K59.0
ICD-10 Finland
Constipation
3.0
6.8
39
138
F61.0
ICD-10 Finland
Mixed personality disorders
5.4
6.8
19
36
M03BX01
ATC
baclofen; systemic
5.4
6.8
19
36
L17
ICPC
Foot/toe symptom/complaint
1.7
6.8
146
938
F32.8
ICD-10 Finland
Other depressive episodes
6.2
6.8
17
28
CKC15
NOMESCO Finland
Panretinal photocoagulation
9.5
6.8
13
14
M79.7
ICD-10 Finland
Fibromyalgia
4.4
6.8
23
54
J11.1
ICD-10 Finland
Influenza with other respiratory manifestations, virus not identified
4.8
6.8
21
45
F50.8
ICD-10 Finland
Other eating disorders
40.5
6.8
8
*
H57.1
ICD-10 Finland
Ocular pain
4.0
6.8
25
64
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.2
6.8
34
112
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
6.7
419
3566
A29
ICPC
General symptom/complaint other
2.2
6.7
68
331
M54.5
ICD-10 Finland
Low back pain
1.7
6.7
162
1080
QDA10
NOMESCO Finland
Incision of skin of lower limb
22.8
6.7
9
*
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.2
6.7
70
346
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.3
6.7
23
55
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
4.3
6.7
23
55
I20.90
ICD-10 Finland
Angina pectoris, unspecified
5.3
6.7
19
37
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.7
6.7
27
75
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
4.1
6.7
24
60
RF210
NOMESCO Finland
NA
4.0
6.7
25
65
N06AX12
ATC
bupropion; oral
2.7
6.6
44
173
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
2.3
6.6
60
275
V03AE02
ATC
sevelamer; oral
12.4
6.6
11
9
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
6.6
194
1361
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
8.8
6.6
13
15
S80.0
ICD-10 Finland
Contusion of knee
2.5
6.6
49
205
RS120
NOMESCO Finland
NA
10.2
6.6
12
12
J01AA02
ATC
doxycycline; systemic
1.6
6.5
347
2826
C10AA05
ATC
atorvastatin; oral
1.8
6.5
127
792
A46
ICD-10 Finland
Erysipelas
2.3
6.5
60
281
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.3
6.5
59
271
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.1
6.5
71
358
K59.09
ICD-10 Finland
Constipation, unspecified
2.7
6.5
42
163
IDY03
NOMESCO Finland
Systematic individual therapy, cognitive-behavioural
3.9
6.5
25
67
T78.4
ICD-10 Finland
Allergy, unspecified
2.9
6.5
38
139
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
7.5
6.4
14
19
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
70.6
6.4
7
*
RS123
NOMESCO Finland
NA
70.6
6.4
7
*
F50.0
ICD-10 Finland
Anorexia nervosa
70.6
6.4
7
*
RJ210
NOMESCO Finland
NA
70.6
6.4
7
*
E10.0
ICD-10 Finland
Type 1 diabetes mellitus, With coma
70.6
6.4
7
*
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
70.6
6.4
7
*
M03BX02
ATC
tizanidine; oral
1.6
6.4
283
2200
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
3.6
6.4
27
78
M01AH02
ATC
rofecoxib; oral
2.3
6.4
57
263
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
8.3
6.4
13
16
V03AE01
ATC
polystyrene sulfonate; oral
8.3
6.4
13
16
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.5
6.3
50
214
K10.3
ICD-10 Finland
Alveolitis of jaws
3.0
6.3
34
118
Z99.2
ICD-10 Finland
Dependence on renal dialysis
18.3
6.3
9
5
U05
ICPC
Urination problems other
3.6
6.3
26
74
N05AH03
ATC
olanzapine; systemic
2.8
6.3
37
136
C09AA05
ATC
ramipril; oral
2.0
6.3
83
452
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
7.1
6.2
14
20
RJ120
NOMESCO Finland
NA
27.0
6.2
8
*
Z70.8
ICD-10 Finland
Other sex counselling
27.0
6.2
8
*
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
27.0
6.2
8
*
S29
ICPC
Skin symptom/complaint other
1.9
6.2
97
560
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
3.5
6.2
27
80
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.0
6.2
83
455
M50.3
ICD-10 Finland
Other cervical disc degeneration
5.4
6.2
17
32
R02
ICPC
Shortness of breath/dyspnoea
2.2
6.2
62
300
A07EA06
ATC
budesonide; oral, local oral
3.6
6.2
26
75
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
6.2
177
1230
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
7.8
6.1
13
17
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.3
6.1
29
92
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
6.1
134
864
SPAT1240
SPAT
Therapeutic discussion
2.0
6.1
78
418
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.5
6.1
26
76
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.1
6.1
68
346
P06
ICPC
Sleep disturbance
2.3
6.1
54
247
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.3
6.1
52
235
N06AX22
ATC
agomelatine; oral
4.2
6.1
21
51
Z00.0
ICD-10 Finland
General medical examination
1.8
6.1
109
661
M89.0
ICD-10 Finland
Algoneurodystrophy
10.2
6.1
11
11
N03AB02
ATC
phenytoin; systemic
10.2
6.1
11
11
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
3.9
6.0
23
61
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
6.1
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
362
2011
2.86
36.81
3.7
2.6
72.4
73.4
nmol/l
0.30
338
1834
232
1021
3.00
36.53
4.4
2.6
6.3
7.4
e6/l
0.40
213
893
276
1339
2.87
36.23
5.7
3.2
—
—
—
0
0
387
2254
2.83
35.46
14.7
7.5
1.2
1.2
mmol/l
0.66
353
1933
280
1388
2.82
35.01
6.1
3.3
7.1
8.1
mmol/l
3.61
248
1198
364
2080
2.75
34.19
13.4
7.1
1.2
1.2
mmol/l
0.98
345
1915
273
1349
2.79
34.17
6.0
3.2
0.3
0.4
e6/l
0.63
232
1009
234
1069
2.88
33.99
5.0
3.3
778.4
119.9
mg/l
1.04
178
713
237
1111
2.81
32.53
5.8
4.1
23.1
10.1
mg/mmol
1.55
176
729
284
1475
2.67
31.65
6.2
3.3
23.1
47.2
e6/l
1.67
242
1130
171
697
2.99
30.15
6.2
5.7
0.8
0.8
mmol/l
0.84
160
662
269
1386
2.63
30.14
13.4
7.3
—
—
—
0
0
137
518
3.10
27.35
12.4
9.6
—
—
—
0
0
205
962
2.67
27.31
4.4
2.8
524.2
587.1
mosm/kgh2o
3.16
188
827
304
1760
2.39
25.37
7.2
3.7
157.0
73.2
e6/l
0.61
245
1205
240
1258
2.46
24.95
9.2
3.8
7.4
7.4
ph
1.86
37
240
138
566
2.84
23.53
12.5
6.3
1.1
1.6
mmol/l
0.85
118
451
235
1247
2.40
23.50
7.7
4.7
92.6
91.2
%
0.39
229
1220
205
1028
2.47
23.20
6.4
4.1
—
—
—
0
0
156
688
2.68
23.07
4.1
2.5
12.8
13.8
umol/l
1.08
143
641
146
626
2.73
22.80
4.3
2.5
2.3
2.4
g/l
1.61
133
580
301
1814
2.25
21.95
11.6
6.7
—
—
—
0
0
405
2793
2.24
20.67
8.7
4.8
7.2
6.4
mmol/l
4.28
388
2553
98
356
3.07
20.65
8.5
5.5
113.1
70.7
ng/l
1.61
90
331
27
33
8.50
20.64
43.8
37.2
7.2
6.3
ug/l
1.27
27
27
133
578
2.65
20.02
4.6
2.6
21.8
23.2
%
0.66
115
507
430
3069
2.24
19.72
15.8
9.2
4.1
3.9
e9/l
1.20
387
2656
367
2472
2.15
19.37
12.3
6.7
0.6
0.7
%
1.22
355
2326
158
761
2.43
19.06
4.9
3.0
4.1
2.5
e6/l
1.00
95
409
262
1579
2.12
18.22
2.0
1.8
95.7
97.0
pmol/l
0.14
131
812
387
2706
2.10
17.94
11.9
6.5
0.0
0.0
e9/l
0.73
346
2331
386
2699
2.09
17.86
11.9
6.5
0.6
0.5
e9/l
1.80
344
2329
344
2310
2.07
17.72
8.8
6.3
10.5
10.6
umol/l
0.09
327
2170
370
2554
2.07
17.64
12.2
6.6
2.9
2.9
%
0.09
359
2396
371
2570
2.06
17.44
12.5
6.8
8.4
8.3
%
0.29
360
2428
112
484
2.59
16.87
11.2
6.9
104.5
104.3
mmol/l
0.16
112
475
110
477
2.58
16.43
6.8
5.5
7.4
7.4
ph
—
7
37
373
2630
2.01
16.20
12.2
6.4
55.5
54.7
%
0.67
360
2488
389
2788
2.02
16.08
12.0
6.5
1.9
2.0
e9/l
0.90
353
2454
168
890
2.21
15.90
1.5
1.4
20.4
20.0
nmol/l
0.13
143
763
280
1797
2.00
15.82
9.9
5.3
34.9
36.7
g/l
5.18
260
1693
374
2658
1.99
15.67
12.4
6.6
29.3
30.7
%
1.78
362
2512
596
5113
3.63
15.66
28.2
12.5
3.9
3.9
mmol/l
0.55
589
4934
389
2803
2.00
15.65
12.9
6.9
0.2
0.2
e9/l
0.05
353
2455
595
5103
3.57
15.56
27.7
12.4
139.1
139.6
mmol/l
6.47
588
4944
204
1182
2.07
15.21
3.0
2.1
150.8
270.7
u/l
1.27
194
1124
187
1054
2.10
14.98
2.7
2.3
2.2
1.0
mg/l
0.78
134
791
196
1125
2.07
14.95
4.4
3.2
—
—
—
0
0
461
3573
2.05
14.53
11.1
6.6
89.8
86.5
u/l
0.53
443
3337
113
524
2.41
14.53
2.8
2.2
316.7
367.4
nmol/l
2.00
106
489
59
196
3.22
14.34
2.3
1.7
—
—
—
0
0
39
98
4.17
14.27
2.7
1.9
—
—
—
0
0
101
449
2.49
14.22
4.9
2.2
44.8
32.9
u/l
0.66
78
377
48
143
3.55
13.84
4.5
3.3
—
—
—
0
0
123
608
2.27
13.59
3.4
1.9
—
—
—
0
0
47
140
3.55
13.55
3.1
2.2
1.3
1.4
g/l
0.14
40
123
89
386
2.52
13.17
7.1
5.7
24.2
24.5
mmol/l
0.54
89
378
92
406
2.48
13.12
7.5
9.4
0.3
0.9
mmol/l
0.61
77
332
444
3456
1.94
13.02
7.1
3.9
—
—
—
0
0
345
2502
1.83
12.39
15.8
9.1
0.0
0.0
e9/l
0.11
287
1993
503
4119
2.06
12.32
7.2
4.9
44.5
38.7
mmol/mol
13.50
470
3868
117
591
2.20
12.19
5.4
4.4
5.3
7.5
umol/l
1.20
102
502
15
17
9.01
12.04
4.0
3.1
—
—
—
0
0
34
90
3.93
11.61
13.6
5.8
—
—
—
0
0
494
4059
1.97
11.42
5.0
3.9
14.2
14.5
pmol/l
2.17
463
3721
120
633
2.10
11.13
1.8
1.6
1131.3
1169.0
nmol/l
0.16
97
479
241
1607
1.80
11.10
9.9
7.0
1.2
1.2
inr
0.26
96
519
214
1380
1.83
10.98
5.6
2.5
75.3
56.7
u/l
0.42
204
1277
190
1187
1.86
10.76
3.3
2.2
—
—
—
0
0
114
599
2.10
10.66
1.3
1.2
—
—
—
0
0
25
56
4.61
10.57
3.6
2.8
—
—
—
0
0
194
1226
1.84
10.56
3.3
2.5
2.9
2.8
mg/l
0.10
170
1057
210
1365
1.80
10.40
4.4
2.5
—
—
—
0
0
192
1218
1.83
10.28
2.0
1.7
1.3
1.4
mmol/l
0.42
172
1051
227
1524
1.76
9.99
3.7
2.3
—
—
—
0
0
36
113
3.32
9.59
4.5
2.9
—
—
—
0
0
233
1594
1.73
9.49
2.1
1.4
2.1
2.3
u/ml
0.07
34
370
80
390
2.20
9.00
7.6
5.9
—
—
—
0
0
34
109
3.24
8.77
9.4
1.9
0.9
0.7
nmol/l
0.30
29
93
546
4778
2.01
8.70
5.8
4.4
1.8
2.1
mu/l
0.69
512
4431
14
22
6.48
8.56
6.0
7.7
3.2
1.8
mg/l
1.25
14
17
105
578
1.98
8.55
2.6
1.6
—
—
—
0
0
27
76
3.67
8.48
15.7
6.8
68.9
64.9
%
0.46
27
76
131
780
1.86
8.42
3.9
3.3
126.1
546.9
ng/l
1.92
94
516
15
26
5.88
8.36
2.6
1.7
—
—
—
0
0
108
605
1.95
8.35
1.3
1.2
—
—
—
0
0
95
517
1.98
7.97
5.9
4.0
1.6
1.6
%
0.18
86
480
537
4724
1.88
7.69
32.3
14.2
13.5
13.4
%
0.49
529
4644
39
149
2.72
7.43
2.1
1.7
—
—
—
0
0
77
399
2.06
7.39
16.5
17.4
1.3
1.3
inr
—
6
64
58
269
2.27
7.35
5.3
2.6
63.2
66.8
g/l
1.84
53
246
48
207
2.43
7.17
9.3
12.6
—
—
—
0
0
320
2503
1.56
7.01
4.7
2.9
83.4
81.9
ug/l
0.07
305
2344
14
27
5.28
7.00
2.0
2.0
557.1
713.8
u/ml
0.37
14
27
42
172
2.54
6.99
2.0
1.6
219.7
210.7
u/ml
0.07
31
88
80
430
1.98
6.94
5.4
2.8
10.0
9.8
g/l
0.15
74
402
378
3075
1.57
6.91
3.7
3.2
—
—
—
0
0
580
5280
2.12
6.88
26.1
11.2
22.1
21.0
mg/l
0.35
471
3958
204
1444
1.61
6.84
2.0
1.5
2.0
2.0
g/l
0.05
102
834
116
1768
0.58
6.55
2.9
2.5
—
—
—
0
0
42
179
2.44
6.45
1.5
1.2
—
—
—
0
0
34
131
2.69
6.40
4.7
2.6
1.3
10.1
e6/l
1.08
25
106
34
131
2.69
6.40
4.7
2.6
41.5
983.9
e6/l
0.62
27
110
10
15
6.76
6.33
1.8
3.1
—
—
—
0
0
120
754
1.73
6.33
2.1
1.5
—
—
—
0
0
12
22
5.54
6.31
1.0
1.0
—
—
—
0
0
18
47
3.91
6.30
6.9
4.2
147.3
217.5
e6/l
0.60
11
28
45
201
2.33
6.24
4.5
2.2
—
—
—
0
0
63
324
2.05
6.17
4.1
3.1
—
—
—
0
0
44
196
2.34
6.14
3.7
3.0
—
—
—
0
0
308
2435
1.51
6.13
4.9
3.3
0.0
0.0
estimate
0.00
69
487
10
16
6.33
5.97
1.0
1.3
—
—
—
0
0
41
180
2.37
5.91
3.2
2.1
—
—
—
0
0
295
2324
1.50
5.90
4.7
4.0
—
—
—
0
0
16
41
3.98
5.74
5.6
4.4
—
—
—
0
0
587
5428
2.06
5.70
16.1
9.2
26.1
26.0
u/l
0.02
571
5234
305
2440
1.48
5.54
7.0
4.5
0.0
0.0
estimate
0.50
68
503
198
1453
1.53
5.46
4.5
3.0
2.4
2.4
mmol/l
0.17
174
1285
26
95
2.81
5.43
3.6
4.1
—
—
—
0
0
122
801
1.65
5.41
1.7
1.6
429.4
9724671.0
pmol/l
0.50
105
689
91
552
1.76
5.40
1.8
1.5
—
—
—
0
0
54
276
2.05
5.39
3.3
2.5
—
—
—
0
0
25
90
2.85
5.36
2.1
1.9
0.6
0.7
g/l
0.39
20
77
54
277
2.04
5.34
2.3
1.9
6.2
8.3
u/l
0.79
39
195
592
5511
2.07
5.32
20.5
10.4
—
—
—
0
0
11
22
5.07
5.28
1.0
1.2
—
—
—
0
0
41
190
2.24
5.25
9.7
5.0
0.6
0.2
g/l
1.27
30
106
26
97
2.75
5.23
1.6
1.6
—
—
—
0
0
67
374
1.88
5.21
4.3
3.3
66.0
69.0
e9/l
0.30
52
276
110
713
1.66
5.12
1.6
1.4
316.2
541.3
titre
1.40
21
152
306
2479
1.45
5.06
5.2
3.3
0.0
0.0
estimate
0.50
65
487
425
3668
1.48
5.01
6.4
4.0
12.2
9.7
mm/h
3.14
401
3386
30
124
2.49
4.95
1.4
1.4
216.4
301.4
ug/g
1.29
17
64
63
351
1.88
4.93
2.6
1.8
1.7
1.2
g/l
0.68
57
329
17
51
3.40
4.91
5.4
4.1
—
—
—
0
0
21
73
2.94
4.80
1.1
1.3
—
—
—
0
0
24
90
2.73
4.80
3.1
2.4
107.3
76.6
ug/min
0.27
18
48
22
79
2.85
4.76
2.2
2.7
—
—
—
0
0
21
74
2.90
4.70
6.9
3.7
—
—
—
0
0
199
1503
1.47
4.66
5.1
3.1
139.8
34.3
ng/l
0.65
142
849
25
99
2.59
4.51
5.5
1.7
36.3
39.3
g/l
1.28
20
87
51
275
1.93
4.42
2.4
3.0
118.4
161.5
ng/l
0.54
45
254
58
328
1.85
4.35
1.8
1.5
—
—
—
0
0
18
61
3.01
4.31
3.2
3.1
931.8
796.6
e6/l
—
5
18
233
1839
1.42
4.24
2.2
2.0
—
—
—
0
0
14
41
3.47
4.20
3.3
1.6
—
—
—
0
0
145
1048
1.50
4.17
5.4
2.9
323.1
5394.8
umol/l
3.59
128
923
17
57
3.04
4.15
1.2
1.3
—
—
—
0
0
61
357
1.78
4.10
2.2
1.7
15.2
18.8
iu/l
0.47
46
274
20
76
2.68
3.93
5.7
3.5
1.4
1.2
e9/l
0.44
12
42
17
59
2.93
3.92
1.9
1.4
—
—
—
0
0
10
24
4.22
3.90
1.1
1.0
—
—
—
0
0
20
77
2.65
3.84
1.2
1.1
—
—
—
0
0
14
44
3.23
3.79
24.4
7.7
11.9
11.5
%
0.14
14
44
509
4656
1.47
3.64
5.2
4.2
2.6
2.8
mmol/l
4.06
475
4336
72
457
1.65
3.64
1.5
1.4
—
—
—
0
0
12
35
3.48
3.63
1.3
1.6
10.2
9.6
umol/l
0.19
12
35
59
355
1.73
3.63
1.5
1.4
—
—
—
0
0
10
26
3.89
3.53
2.2
1.7
—
—
—
0
0
6
6
10.08
3.50
1.0
1.2
—
—
—
0
0
57
344
1.72
3.47
3.0
2.1
10.2
11.6
nmol/l
0.39
38
301
35
181
1.99
3.45
13.2
3.8
0.5
0.7
%
1.55
35
175
15
54
2.82
3.27
1.5
1.3
—
—
nmol/l
—
0
0
15
54
2.82
3.27
8.9
4.7
—
—
—
0
0
26
123
2.16
3.24
1.5
1.3
—
—
—
0
0
54
328
1.71
3.23
5.2
4.8
1.2
1.2
mmol/l
0.14
49
286
23
106
2.21
3.06
2.0
2.4
131.6
132.5
g/l
0.05
17
83
55
341
1.67
3.06
3.7
3.4
4.4
4.8
pmol/l
2.63
50
309
115
842
1.45
3.06
3.3
2.8
111.9
101.2
ug/g
0.20
94
666
498
4582
1.40
3.06
4.8
3.8
1.4
1.5
mmol/l
2.35
467
4278
500
4605
1.40
3.04
4.9
3.9
4.5
4.7
mmol/l
4.64
470
4319
18
75
2.44
2.99
1.5
1.4
—
—
—
0
0
24
114
2.15
2.98
1.9
2.6
—
—
—
0
0
19
82
2.36
2.94
6.3
5.1
418.5
379.4
umol/l
0.88
19
77
13
46
2.86
2.93
1.2
1.5
—
—
—
0
0
23
110
2.13
2.82
1.2
1.1
—
—
—
0
0
73
496
1.53
2.80
1.5
1.3
—
—
—
0
0
25
124
2.06
2.80
2.6
1.7
0.6
3.7
ug/l
0.82
20
113
33
568
0.56
2.77
1.2
1.3
—
—
—
0
0
52
327
1.64
2.76
1.2
1.2
—
—
—
0
0
7
14
5.04
2.73
1.3
1.0
—
—
—
0
0
14
54
2.63
2.72
1.1
1.2
—
—
—
0
0
479
4411
1.35
2.68
4.4
3.5
1.3
1.2
mmol/l
0.93
446
4107
53
338
1.62
2.67
2.9
1.8
—
—
—
0
0
17
358
0.46
2.66
1.4
1.3
—
—
—
0
0
32
177
1.85
2.65
1.5
1.2
—
—
—
0
0
48
300
1.65
2.62
1.4
1.3
—
—
—
0
0
19
87
2.22
2.59
1.1
1.1
—
—
—
0
0
18
81
2.26
2.56
8.9
3.8
19.6
28.6
mg/l
0.97
13
66
18
81
2.26
2.56
8.9
3.8
62.1
55.0
mg/l
0.08
13
66
6
11
5.50
2.55
18.3
7.1
—
—
—
0
0
42
256
1.69
2.52
5.6
2.4
—
—
—
0
0
9
26
3.50
2.49
1.1
1.1
—
—
—
0
0
9
26
3.50
2.49
3.8
3.0
—
—
—
0
0
7
16
4.41
2.48
3.4
3.1
1.1
1.1
umol/l
—
7
16
7
16
4.41
2.48
3.0
1.6
—
—
—
0
0
46
289
1.64
2.47
3.1
1.9
—
—
—
0
0
36
212
1.74
2.45
4.9
6.6
—
—
—
0
0
49
318
1.59
2.32
1.5
1.5
—
—
—
0
0
67
467
1.49
2.31
1.1
1.3
40.1
157.6
iu/ml
—
9
190
12
47
2.58
2.28
1.1
1.1
—
—
—
0
0
8
23
3.51
2.27
1.6
1.8
2.9
9.7
nmol/l
—
8
18
17
79
2.18
2.26
3.4
3.1
—
—
—
0
0
7
18
3.92
2.25
1.1
1.4
138.7
128.6
nmol/l
—
7
18
11
42
2.65
2.19
3.6
4.1
26.8
28.6
umol/l
0.24
11
42
15
67
2.27
2.19
1.0
1.2
—
—
—
0
0
52
349
1.53
2.15
4.1
3.8
2.6
40.7
ug/l
0.97
44
279
15
68
2.24
2.12
1.1
1.4
—
—
—
0
0
5
10
5.03
2.07
3.0
3.5
—
16.4
—
0
5
7
20
3.53
2.06
1.6
3.5
29.3
39.0
umol/l
—
7
14
173
1434
1.28
2.04
2.4
2.0
—
—
—
0
0
53
364
1.50
1.98
2.9
1.8
—
—
—
0
0
53
366
1.49
1.94
2.9
1.8
—
—
—
0
0
159
1313
1.28
1.93
4.8
3.5
0.0
0.0
estimate
0.80
61
491
17
85
2.03
1.92
6.7
4.4
—
—
—
0
0
107
839
1.33
1.90
1.3
1.3
41.3
27.0
iu/ml
0.31
32
248
12
52
2.33
1.88
1.1
1.1
—
—
—
0
0
53
369
1.48
1.87
2.9
1.8
—
—
—
0
0
8
28
2.88
1.86
1.4
1.1
—
—
—
0
0
5
12
4.19
1.82
5.0
2.3
—
—
—
0
0
535
5091
1.32
1.80
31.3
12.7
39.5
39.9
%
0.73
456
4093
7
23
3.07
1.80
1.3
1.4
—
—
—
0
0
8
30
2.69
1.73
1.4
1.4
—
—
—
0
0
16
82
1.98
1.71
1.3
1.2
5.1
3.6
u/ml
—
8
34
42
286
1.50
1.67
2.6
2.1
11.0
6.7
ug/l
0.33
34
248
18
98
1.86
1.63
1.2
1.1
351.7
149.0
iu/ml
—
6
28
18
99
1.84
1.58
1.2
1.2
—
—
—
0
0
6
20
3.02
1.58
1.5
4.8
—
—
—
0
0
612
5977
1.63
1.58
36.4
16.8
6.8
6.7
e9/l
1.05
607
5794
12
58
2.09
1.50
3.4
1.8
—
—
—
0
0
33
219
1.53
1.49
1.3
1.3
—
—
—
0
0
49
355
1.41
1.45
3.5
4.6
1.1
0.4
%
0.64
14
85
72
556
1.33
1.44
1.4
1.2
—
—
—
0
0
23
141
1.65
1.43
2.3
3.7
10.4
8.6
umol/l
0.12
17
112
50
365
1.40
1.42
3.0
1.7
—
—
—
0
0
29
190
1.55
1.40
1.4
1.7
—
—
—
0
0
16
89
1.82
1.38
2.8
2.4
19.2
17.0
%
—
9
42
50
367
1.39
1.38
7.7
4.0
—
—
—
0
0
25
159
1.60
1.36
1.2
1.2
—
—
—
0
0
10
47
2.15
1.34
1.3
1.4
—
—
—
0
0
11
54
2.06
1.33
1.3
1.4
—
—
—
0
0
48
353
1.39
1.32
3.6
5.0
0.0
0.0
%
0.99
13
92
23
145
1.61
1.30
2.5
1.9
4.3
6.4
iu/l
—
9
52
31
210
1.50
1.30
2.7
2.4
—
—
—
0
0
11
55
2.02
1.28
2.4
1.8
—
—
—
0
0
8
35
2.30
1.27
1.4
1.5
7.7
7.2
ug/l
—
8
29
6
25
2.41
1.24
6.3
2.4
117.0
121.0
ug/l
—
6
25
6
25
2.41
1.24
2.0
4.0
—
—
—
0
0
12
63
1.92
1.23
1.4
1.6
—
—
—
0
0
17
101
1.70
1.21
3.2
5.3
1.7
2.7
mmol/l
0.97
11
60
8
39
2.06
1.15
2.0
3.5
—
—
—
0
0
51
390
1.33
1.13
3.6
4.8
0.6
0.8
%
0.29
16
122
14
81
1.74
1.09
2.5
1.7
—
—
—
0
0
14
81
1.74
1.09
2.5
1.7
—
—
—
0
0
14
81
1.74
1.09
2.5
1.7
—
—
—
0
0
14
81
1.74
1.09
2.5
1.7
—
—
—
0
0
5
21
2.39
1.09
1.0
1.3
—
—
—
0
0
8
41
1.96
1.09
1.4
1.1
—
—
—
0
0
7
33
2.13
1.06
1.7
2.7
—
—
—
0
0
12
67
1.81
1.05
7.6
3.8
—
—
—
0
0
5
22
2.28
1.03
1.2
1.2
—
—
—
0
0
9
47
1.93
1.02
2.7
2.8
7.7
3.4
nmol/l
—
9
47
9
47
1.93
1.02
1.1
1.8
30.0
33.5
pg
—
9
47
7
36
1.95
0.97
1.1
1.1
—
—
—
0
0
10
54
1.87
0.97
2.1
2.0
—
—
—
0
0
21
303
0.68
0.94
1.3
1.6
—
—
—
0
0
46
579
0.78
0.88
2.0
1.9
—
—
—
0
0
81
685
1.21
0.83
3.5
2.5
2.5
2.4
mmol/l
0.30
72
586
6
32
1.88
0.82
1.5
1.6
0.8
1.1
g/l
—
6
32
77
907
0.83
0.82
1.8
1.7
—
—
—
0
0
46
367
1.27
0.79
3.8
4.9
0.3
0.2
%
0.26
16
109
58
476
1.24
0.79
1.5
1.4
—
—
—
0
0
6
33
1.83
0.79
1.3
1.2
—
—
—
0
0
133
1182
1.16
0.77
2.2
1.7
—
—
—
0
0
5
25
2.01
0.73
9.2
3.2
—
—
—
0
0
5
27
1.86
0.68
2.0
2.9
—
—
—
0
0
5
30
1.67
0.61
1.0
1.4
738400.0
18893.6
e6/l
—
5
19
13
88
1.49
0.61
1.3
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
2.1
—
1.0
—
0
16
10
149
0.67
0.57
3.7
8.9
—
—
—
0
0
92
818
1.15
0.56
1.3
1.2
6.4
9.0
u/ml
0.26
29
318
120
1089
1.13
0.54
5.2
3.3
1.0
1.0
kg/l
0.09
21
142
18
134
1.35
0.53
6.3
5.3
—
—
—
0
0
6
100
0.60
0.52
10.7
3.6
—
—
—
0
0
41
345
1.20
0.49
2.6
2.1
4.6
4.0
e9/l
0.78
33
290
7
50
1.40
0.45
1.0
1.1
—
—
—
0
0
5
31
1.62
0.43
11.8
8.4
0.6
0.6
mmol/l
—
5
31
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
5
32
1.57
0.42
1.0
1.3
—
—
—
0
0
8
58
1.38
0.41
1.6
1.2
—
—
—
0
0
5
34
1.47
0.40
2.2
1.2
13.3
41.7
nmol/l
—
5
28
6
47
1.28
0.32
1.3
1.2
—
—
—
0
0
6
47
1.28
0.32
2.5
4.4
—
—
—
0
0
458
4491
1.07
0.31
4.4
3.7
6.2
5.7
mmol/l
4.00
420
4112
22
185
1.20
0.29
1.1
1.1
—
—
—
0
0
7
56
1.25
0.29
35.3
4.1
5.7
6.1
mmol/l
—
7
45
44
397
1.12
0.25
2.5
2.3
10144.9
3869.3
u/l
0.43
12
151
9
75
1.20
0.25
1.2
1.2
—
—
—
0
0
117
1109
1.07
0.24
4.8
3.2
—
—
—
0
0
5
38
1.32
0.23
11.2
19.6
1306.4
1476.7
nmol/l
—
5
38
5
41
1.22
0.22
1.4
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
23
259
0.88
0.19
1.1
1.1
—
—
—
0
0
22
194
1.14
0.18
1.1
1.2
0.5
1.7
u/ml
0.82
12
118
14
120
1.17
0.16
1.0
1.1
—
—
—
0
0
14
120
1.17
0.16
1.0
1.1
—
—
—
0
0
90
863
1.05
0.14
4.9
4.5
1.7
2.5
ug/l
1.16
79
772
22
201
1.10
0.11
1.1
1.2
5.5
9.1
u/ml
0.40
15
130
117
1203
0.97
0.10
5.3
4.8
—
—
—
0
0
5
45
1.11
0.10
1.2
1.2
—
—
—
0
0
5
47
1.06
0.09
1.4
1.3
—
—
—
0
0
20
217
0.92
0.09
1.5
1.5
—
—
—
0
0
143
1400
1.03
0.08
4.3
3.0
—
—
—
0
0
15
136
1.11
0.08
2.5
1.5
44.5
37.9
nmol/l
0.36
15
131
6
57
1.05
0.08
1.2
1.2
14.0
15.0
u/l
—
6
50
96
937
1.03
0.07
1.7
1.6
—
—
—
0
0
9
84
1.07
0.07
1.6
1.8
—
—
—
0
0
9
86
1.05
0.07
1.0
1.1
—
—
—
0
0
20
213
0.94
0.06
1.5
1.4
—
—
—
0
0
14
129
1.09
0.05
1.1
1.2
—
—
—
0
0
20
212
0.94
0.05
1.5
1.4
—
—
—
0
0
10
109
0.92
0.04
2.5
3.9
56.2
54.8
%
—
10
109
168
1665
1.01
0.03
1.6
1.6
—
—
—
0
0
11
118
0.93
0.03
1.1
1.1
0.7
1.1
u/ml
—
6
35
10
93
1.08
0.02
1.0
1.1
—
—
—
0
0
10
107
0.93
0.02
2.4
3.5
4.4
4.1
e9/l
—
10
107
49
497
0.98
0.01
3.2
2.9
0.6
0.8
ug/l
0.98
39
306
45
456
0.99
0.00
5.8
3.5
—
—
—
0
0
12
115
1.04
0.00
1.2
1.3
—
—
—
0
0
22
225
0.98
0.00
1.1
1.2
0.6
2.4
u/ml
1.26
15
121
19
194
0.98
0.00
1.2
1.1
1.4
3.7
u/ml
—
8
49
25
254
0.98
0.00
1.0
1.4
119.6
265.2
miu/ml
0.99
11
131
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
0.00
0.0
10.8
—
—
—
0
0
0
8
0.00
0.00
0.0
2.8
—
4.3
—
0
8
8
87
0.92
0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
10411.4
—
0
7
0
5
0.00
0.00
0.0
2.2
—
9.6
—
0
5
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
3.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint F5_PHYSBEHOTH and mortality.

Females

Parameter HR [95% CI] p-value
F5_PHYSBEHOTH 3.716 [3.0, 4.6] < 0.001
Birth year 0.991 [0.98, 1.0] 0.041

During the follow-up period (1.1.1998 — 31.12.2019), 316 out of 2207 females with F5_PHYSBEHOTH died.

Males

Parameter HR [95% CI] p-value
F5_PHYSBEHOTH 3.261 [2.58, 4.12] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 261 out of 1537 males with F5_PHYSBEHOTH died.

Mortality risk

Mortality risk for people of age

years, who have F5_PHYSBEHOTH.

N-year risk Females Males
1 0.399% 0.601%
5 1.878% 3.387%
10 4.839% 8.455%
15 9.05% 15.842%
20 15.128% 25.809%

Relationships between endpoints

Index endpoint: F5_PHYSBEHOTH – Unspecified behavioural syndromes associated with physiological disturbances and physical factors +Physiological and behavioural factors associated with disorders of diseases classified elsewhere

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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