Sleep terrors [night terrors]

F5_SLEEPTERRORS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F51.4
  • Cause of death: ICD-10 F51.4

2 out of 7 registries used, show all original rules.

83

4. Check minimum number of events

None

83

5. Include endpoints

None

83

6. Filter based on genotype QC (FinnGen only)

83

Control definitions (FinnGen only)

Control exclude
F5_SLEEP

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1681 662 1017
Only index persons 1307 520 787
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.03
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population 6.64 6.09 6.94
Only index persons 7.71 7.32 7.97

-FinnGen-

Key figures

All Female Male
Number of individuals 83 63 20
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 14.48 16.02 9.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
73
Matched controls
730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F51.4
ICD-10 Finland
Sleep terrors [night terrors]
+∞
104.9
73
*
F51.9
ICD-10 Finland
Nonorganic sleep disorder, unspecified
+∞
12.9
12
*
G47.9
ICD-10 Finland
Sleep disorder, unspecified
42.5
9.3
11
*
IAB13
NOMESCO Finland
Psychiatric sleep disorder consultation
+∞
7.4
7
*
Z01.8
ICD-10 Finland
Other specified special examinations
4.7
6.6
24
69
IEY18
NOMESCO Finland
Psychiatric sleep coaching, individual
+∞
6.3
6
*
F51.3
ICD-10 Finland
Sleepwalking [somnambulism]
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
30
157
2.43
3.44
4.2
3.2
—
—
—
0
0
16
62
2.96
3.27
2.8
2.8
—
—
—
0
0
30
161
2.35
3.23
6.2
2.9
—
—
—
0
0
35
206
2.21
3.00
4.1
7.1
—
—
—
0
0
20
94
2.49
2.83
1.3
1.3
53.1
25.2
iu/ml
—
5
29
41
262
2.12
2.81
3.7
3.0
—
—
—
0
0
28
159
2.15
2.56
6.5
3.1
0.1
0.2
e6/l
0.56
20
119
47
326
2.02
2.50
6.1
4.9
0.0
0.0
estimate
—
8
79
47
326
2.02
2.50
4.9
3.3
0.0
0.0
estimate
—
6
78
19
94
2.32
2.40
1.4
1.3
16.5
9.6
u/ml
—
6
38
30
180
2.04
2.36
6.1
3.0
20.3
93.9
e6/l
1.23
23
137
29
172
2.05
2.35
2.6
1.6
94.3
87.7
pmol/l
0.35
16
102
47
331
1.97
2.34
5.1
3.5
0.0
0.0
estimate
—
6
75
32
199
1.99
2.27
1.6
1.7
—
—
—
0
0
22
121
2.11
2.15
6.1
2.2
10.5
9.2
e6/l
0.16
17
106
44
311
1.88
2.10
3.2
2.4
—
—
—
0
0
34
221
1.91
2.09
6.8
3.6
19.4
53.7
e6/l
0.96
23
143
46
331
1.87
2.06
4.2
6.2
0.0
0.0
e9/l
0.43
38
295
46
331
1.87
2.06
4.2
6.2
0.5
0.5
e9/l
0.06
38
295
10
40
2.71
1.91
4.0
3.2
—
—
—
0
0
15
74
2.25
1.89
1.9
1.6
—
—
—
0
0
14
67
2.31
1.89
1.6
1.8
328.6
376.4
nmol/l
0.41
14
61
48
357
1.82
1.88
4.1
6.1
1.9
2.1
e9/l
0.74
42
322
16
83
2.15
1.79
2.4
2.2
—
—
—
0
0
17
91
2.09
1.76
2.3
2.1
—
—
—
0
0
46
343
1.77
1.74
5.1
6.7
0.1
0.2
e9/l
1.68
39
308
25
155
1.88
1.73
2.0
1.8
2.9
2.7
mg/l
0.17
18
130
17
92
2.07
1.71
2.3
2.2
—
—
—
0
0
17
92
2.07
1.71
2.3
2.2
—
—
—
0
0
17
92
2.07
1.71
2.3
2.1
—
—
—
0
0
5
14
3.73
1.64
13.8
19.4
1.3
1.1
mg/l
—
5
14
19
110
1.94
1.60
6.7
2.4
539.5
569.9
mosm/kgh2o
0.23
14
92
13
65
2.19
1.59
1.5
1.8
—
—
—
0
0
11
51
2.33
1.58
1.5
1.1
—
—
—
0
0
24
155
1.77
1.44
4.4
2.9
50.3
52.1
u/l
0.15
24
145
7
29
2.54
1.42
1.1
1.3
—
—
—
0
0
14
76
2.01
1.40
2.5
2.3
—
—
—
0
0
8
34
2.49
1.33
1.5
1.3
—
—
—
0
0
9
44
2.17
1.31
2.7
2.3
—
—
—
0
0
56
463
1.64
1.27
6.4
3.9
—
—
—
0
0
21
135
1.74
1.27
4.0
2.2
9.9
12.3
ng/l
—
8
55
12
64
2.02
1.25
1.8
2.6
—
—
—
0
0
5
20
2.59
1.17
1.6
29.7
—
—
—
0
0
7
30
2.45
1.15
1.9
1.6
—
—
—
0
0
74
672
1.93
1.13
17.6
11.1
39.6
39.8
%
0.07
60
576
28
201
1.59
1.12
3.1
2.2
—
—
—
0
0
25
175
1.61
1.10
7.9
5.0
—
—
—
0
0
5
21
2.47
1.10
1.0
1.3
—
—
—
0
0
47
384
1.52
1.04
8.0
8.4
4.2
3.9
e9/l
0.38
40
338
7
36
2.03
0.99
1.6
1.5
—
—
—
0
0
76
704
1.94
0.98
12.3
8.3
—
—
—
0
0
42
338
1.49
0.98
3.6
6.1
6.0
6.2
mmol/l
0.17
36
291
23
164
1.56
0.93
2.3
2.3
—
—
—
0
0
6
29
2.15
0.91
1.5
1.1
—
—
—
0
0
19
131
1.58
0.88
3.5
2.5
22.9
75.4
ug/g
2.68
14
93
17
116
1.59
0.82
4.5
3.7
—
—
—
0
0
8
48
1.74
0.81
1.6
1.3
—
—
—
0
0
21
152
1.51
0.79
3.4
4.2
1.0
1.0
inr
—
9
56
6
34
1.82
0.78
6.0
12.9
5.9
5.8
mmol/l
—
6
34
5
23
2.25
0.77
1.0
1.1
—
—
—
0
0
39
321
1.41
0.76
6.5
8.1
0.0
0.0
e9/l
0.00
29
260
7
38
1.92
0.76
7.6
2.2
—
—
—
0
0
5
25
2.06
0.74
1.4
1.2
—
—
—
0
0
5
25
2.06
0.74
1.0
1.1
—
—
—
0
0
15
209
0.66
0.71
2.3
1.7
—
—
—
0
0
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
10
65
1.61
0.58
1.3
1.3
—
—
—
0
0
21
263
0.73
0.55
2.0
1.8
—
—
—
0
0
6
39
1.58
0.54
1.0
1.1
—
—
—
0
0
5
81
0.59
0.48
1.4
1.4
—
—
—
0
0
27
223
1.31
0.48
1.3
1.4
1.8
1.9
g/l
0.37
15
119
18
141
1.35
0.45
1.8
2.4
0.5
0.9
mg/l
1.26
12
100
10
70
1.49
0.44
8.3
8.9
1.1
1.2
mmol/l
—
10
65
8
60
1.37
0.42
1.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
13
98
1.39
0.40
5.0
3.6
187.9
112.7
mg/l
—
8
68
13
100
1.36
0.36
5.5
4.3
27.7
21.1
mg/mmol
—
7
73
6
45
1.36
0.34
12.3
10.7
—
—
—
0
0
12
92
1.36
0.34
4.0
2.9
—
—
—
0
0
6
46
1.33
0.34
4.7
11.7
21.4
25.3
mmol/l
—
6
46
39
351
1.21
0.32
2.7
2.2
—
—
—
0
0
23
267
0.81
0.32
2.4
1.8
—
—
—
0
0
5
70
0.70
0.27
5.0
3.1
—
—
—
0
0
22
190
1.21
0.26
7.1
3.3
0.0
0.0
estimate
—
8
78
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.2
—
0
5
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
3.2
—
3.1
—
0
12
0
12
0.00
0.21
0.0
3.3
—
54.0
—
0
12
0
13
0.00
0.21
0.0
1.0
—
0.3
—
0
6
15
174
0.83
0.20
1.6
1.6
—
—
—
0
0
7
59
1.20
0.18
8.3
9.2
—
—
—
0
0
7
61
1.16
0.18
1.0
1.1
—
—
—
0
0
8
67
1.21
0.17
1.3
1.6
—
—
—
0
0
11
95
1.18
0.12
1.8
2.1
—
—
—
0
0
27
252
1.11
0.11
1.3
1.5
1.1
1.6
u/ml
—
7
48
25
267
0.91
0.10
2.1
1.8
—
—
—
0
0
5
46
1.09
0.10
1.6
11.5
105.8
104.4
mmol/l
—
5
46
15
143
1.06
0.01
1.5
1.5
—
—
—
0
0
18
173
1.05
0.01
2.1
4.0
—
—
—
0
0
67
664
1.05
0.00
15.4
9.9
18.9
21.1
mg/l
0.26
54
474
20
197
1.02
0.00
4.8
2.9
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
14.0
—
0
6
6
63
0.95
0.00
1.8
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
9
93
0.96
0.00
1.4
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.3
—
2.0
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
10.7
—
59.0
—
0
6
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
6
62
0.97
0.00
1.8
1.5
—
—
—
0
0
8
87
0.91
0.00
1.3
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
39.0
—
12.3
—
0
5
6
62
0.97
0.00
1.8
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
112.8
—
0
6
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
4.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
1.2
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
11.3
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint F5_SLEEPTERRORS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have F5_SLEEPTERRORS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: F5_SLEEPTERRORS – Sleep terrors [night terrors]

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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