Sleep terrors [night terrors]

F5_SLEEPTERRORS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F51.4
  • Cause of death: ICD-10 F51.4

2 out of 7 registries used, show all original rules.

85

4. Check minimum number of events

None

85

5. Include endpoints

None

85

6. Filter based on genotype QC (FinnGen only)

78

Control definitions (FinnGen only)

Control exclude
F5_SLEEP

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1681 662 1017
Only index persons 1307 520 787
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.03
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population 6.64 6.09 6.94
Only index persons 7.71 7.32 7.97

-FinnGen-

Key figures

All Female Male
Number of individuals 78 60 18
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 15.41 17.22 9.36

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
85
Matched controls
850
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F51.4
ICD-10 Finland
Sleep terrors [night terrors]
+∞
122.4
85
*
F51.0
ICD-10 Finland
Nonorganic insomnia
+∞
27.6
25
*
IAB13
NOMESCO Finland
Psychiatric sleep disorder consultation
+∞
11.7
11
*
G47.9
ICD-10 Finland
Sleep disorder, unspecified
22.4
10.7
15
8
F51.9
ICD-10 Finland
Nonorganic sleep disorder, unspecified
37.8
10.7
13
*
IEY18
NOMESCO Finland
Psychiatric sleep coaching, individual
+∞
8.5
8
*
F51.3
ICD-10 Finland
Sleepwalking [somnambulism]
+∞
7.4
7
*
Z01.8
ICD-10 Finland
Other specified special examinations
4.0
7.0
25
81
IBB02
NOMESCO Finland
Psychiatric evaluation of working capacity and rehabilitation
+∞
6.3
6
*
R51.80
ICD-10 Finland
Headache
3.4
6.2
29
112

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
30
151
2.52
3.76
4.2
3.0
—
—
—
0
0
16
60
3.05
3.46
2.8
2.9
—
—
—
0
0
21
93
2.67
3.37
1.2
1.3
53.10
13.07
iu/ml
—
5
32
46
293
2.24
3.29
3.2
2.5
—
—
—
0
0
30
161
2.33
3.21
6.2
2.8
—
—
—
0
0
13
45
3.23
3.18
1.4
1.1
—
—
—
0
0
48
321
2.14
2.93
6.0
4.4
0.00
0.00
estimate
—
8
81
48
322
2.13
2.90
4.8
3.1
0.00
0.00
estimate
—
8
85
48
325
2.10
2.80
5.0
3.2
0.00
0.00
estimate
—
6
75
20
96
2.42
2.70
1.4
1.3
16.45
8.35
u/ml
—
6
39
30
172
2.15
2.68
2.6
1.7
94.91
88.62
pmol/l
0.35
17
101
16
69
2.62
2.68
1.9
1.7
—
—
—
0
0
28
157
2.17
2.64
6.5
2.9
0.10
0.23
e6/l
0.59
20
116
30
173
2.13
2.64
6.1
2.9
20.27
70.16
e6/l
0.78
23
129
33
199
2.08
2.58
1.6
1.6
—
—
—
0
0
45
309
1.97
2.41
4.0
7.3
—
—
—
0
0
47
328
1.97
2.40
4.2
6.6
0.55
0.54
e9/l
0.05
39
288
47
328
1.97
2.40
4.2
6.6
0.04
0.04
e9/l
0.29
39
288
49
351
1.94
2.28
4.1
6.5
1.95
2.10
e9/l
0.73
43
318
22
119
2.15
2.24
6.1
2.2
10.45
9.11
e6/l
0.17
17
104
34
218
1.93
2.18
6.8
3.4
19.43
71.63
e6/l
1.14
23
138
10
37
2.92
2.15
4.0
3.5
—
—
—
0
0
9
31
3.12
2.14
1.6
2.0
—
—
—
0
0
15
70
2.39
2.13
1.6
2.1
338.33
378.38
nmol/l
0.35
15
63
9
32
3.02
2.07
1.4
1.2
—
—
—
0
0
47
341
1.85
2.02
5.0
7.6
0.14
0.17
e9/l
1.49
40
306
17
87
2.19
1.97
2.3
2.1
—
—
—
0
0
25
149
1.96
1.95
2.0
1.9
2.93
2.64
mg/l
0.19
18
126
18
97
2.09
1.83
2.2
2.1
—
—
—
0
0
18
98
2.06
1.79
2.2
2.1
—
—
—
0
0
18
98
2.06
1.79
2.2
2.1
—
—
—
0
0
18
98
2.06
1.79
2.2
2.1
—
—
—
0
0
6
18
3.50
1.78
1.0
1.1
—
—
—
0
0
13
62
2.29
1.76
1.7
2.8
—
—
—
0
0
5
13
4.01
1.74
13.8
21.5
1.35
1.12
mg/l
—
5
13
24
148
1.87
1.68
4.4
2.9
50.25
55.37
u/l
0.48
24
139
32
217
1.76
1.65
7.2
9.6
1.21
1.22
mmol/l
0.21
27
183
58
465
1.78
1.65
6.3
3.6
—
—
—
0
0
21
128
1.85
1.51
4.0
2.2
9.91
12.18
ng/l
—
8
51
19
113
1.88
1.47
6.7
2.4
539.50
585.73
mosm/kgh2o
0.38
14
94
6
22
2.85
1.46
1.3
1.2
—
—
—
0
0
21
130
1.82
1.44
3.2
2.4
21.77
63.75
ug/g
2.12
16
87
48
375
1.64
1.41
7.9
9.2
4.18
3.89
e9/l
0.35
41
327
26
174
1.71
1.37
7.7
6.0
—
—
—
0
0
14
77
1.98
1.35
2.5
2.3
—
—
—
0
0
8
34
2.49
1.33
1.1
1.3
—
—
—
0
0
78
713
2.14
1.23
12.1
7.9
—
—
—
0
0
42
327
1.56
1.19
3.6
6.4
6.04
6.33
mmol/l
0.40
36
285
24
163
1.66
1.19
2.3
2.2
—
—
—
0
0
5
20
2.59
1.17
1.6
29.7
—
—
—
0
0
7
32
2.29
1.11
1.9
1.5
—
—
—
0
0
13
75
1.87
1.10
1.5
1.7
—
—
—
0
0
9
45
2.12
1.09
1.6
1.4
—
—
—
0
0
9
47
2.02
1.06
2.7
2.3
—
—
—
0
0
17
109
1.70
1.03
4.5
3.6
—
—
—
0
0
40
317
1.49
1.00
6.4
8.3
0.00
0.00
e9/l
-0.00
29
254
28
207
1.53
0.97
3.0
2.0
—
—
—
0
0
6
27
2.31
0.95
1.5
1.1
—
—
—
0
0
9
54
1.74
0.77
1.2
1.3
—
—
—
0
0
5
23
2.24
0.77
1.0
1.3
—
—
—
0
0
5
24
2.15
0.76
1.0
1.1
—
—
—
0
0
23
172
1.46
0.74
5.3
6.6
1.01
1.04
inr
—
9
58
5
26
1.98
0.72
1.4
1.0
0.49
6.11
u/ml
—
5
16
10
62
1.69
0.68
1.3
1.4
—
—
—
0
0
28
224
1.37
0.62
1.3
1.4
1.78
1.95
g/l
0.47
16
119
0
22
0.00
0.60
0.0
1.1
—
—
—
0
0
6
35
1.77
0.59
6.0
12.8
5.88
6.54
mmol/l
—
6
35
6
37
1.67
0.57
8.7
2.1
—
—
—
0
0
16
211
0.70
0.56
2.3
1.8
—
—
—
0
0
40
343
1.31
0.55
2.7
2.1
—
—
—
0
0
9
63
1.48
0.54
1.2
1.6
—
—
—
0
0
13
93
1.47
0.52
3.8
3.0
—
—
—
0
0
18
138
1.39
0.51
1.8
2.5
0.47
1.04
mg/l
1.59
12
98
7
47
1.53
0.49
1.6
3.1
4.30
4.95
pmol/l
—
7
41
22
267
0.76
0.45
2.0
1.8
—
—
—
0
0
13
98
1.39
0.40
2.2
2.3
—
—
—
0
0
22
181
1.29
0.40
7.1
3.0
0.00
0.01
estimate
—
8
79
5
80
0.60
0.37
1.4
1.4
—
—
—
0
0
6
41
1.50
0.37
1.0
1.1
—
—
—
0
0
6
46
1.33
0.34
4.7
11.8
21.42
25.21
mmol/l
—
6
46
13
102
1.32
0.32
5.0
3.6
187.88
77.15
mg/l
—
8
70
7
56
1.27
0.30
1.1
1.3
—
—
—
0
0
29
255
1.21
0.29
1.4
1.4
1.00
1.14
u/ml
—
8
49
13
104
1.30
0.28
5.4
4.3
27.69
16.88
mg/mmol
—
7
76
0
11
0.00
0.21
0.0
2.8
—
3.46
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.9
—
54.27
—
0
11
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.26
—
0
6
6
48
1.27
0.21
12.3
11.0
—
—
—
0
0
7
58
1.23
0.19
8.3
9.3
—
—
—
0
0
69
667
1.18
0.18
15.2
9.2
18.91
20.53
mg/l
0.19
55
473
16
139
1.19
0.18
1.4
1.4
—
—
—
0
0
5
67
0.73
0.17
5.0
2.8
—
—
—
0
0
21
192
1.12
0.12
4.6
2.7
—
—
—
0
0
5
45
1.12
0.10
1.6
12.4
105.80
104.38
mmol/l
—
5
45
7
65
1.08
0.08
1.9
1.5
—
—
—
0
0
7
65
1.08
0.08
1.0
1.1
—
—
—
0
0
7
65
1.08
0.08
1.9
1.5
—
—
—
0
0
25
265
0.92
0.08
2.3
1.9
—
—
—
0
0
7
68
1.03
0.08
1.9
1.6
—
—
—
0
0
16
170
0.93
0.04
1.7
1.6
—
—
—
0
0
26
265
0.97
0.00
2.1
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7.40
—
0
5
0
6
0.00
-0.00
0.0
2.2
—
11.33
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
0.67
—
0
6
0
8
0.00
-0.00
0.0
4.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
126.90
—
0
5
0
5
0.00
-0.00
0.0
2.6
—
15.60
—
0
5
0
7
0.00
-0.00
0.0
1.6
—
1.19
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1633.50
—
0
6
8
86
0.92
-0.00
1.3
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
10.7
—
59.00
—
0
6
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
9.56
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
-0.00
1.4
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
35800.00
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint F5_SLEEPTERRORS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have F5_SLEEPTERRORS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: F5_SLEEPTERRORS – Sleep terrors [night terrors]

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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