Other bursitis, not elsewhere classified

M13_BURSITISOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M71.5
  • Hospital discharge: ICD-9 7273
  • Cause of death: ICD-10 M71.5
  • Cause of death: ICD-9 7273

2 out of 7 registries used, show all original rules.

368

4. Check minimum number of events

None

368

5. Include endpoints

None

368

6. Filter based on genotype QC (FinnGen only)

368

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Parent code in ICD-10
M71
Name in latin
Alia bursitis non alibi classificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2968 1448 1495
Only index persons 2403 1236 1167
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.04
Only index persons 0.05 0.05 0.04
Median age at first event (years)
Whole population 50.46 52.17 48.69
Only index persons 47.55 49.66 45.32

-FinnGen-

Key figures

All Female Male
Number of individuals 368 197 171
Unadjusted period prevalence (%) 0.07 0.07 0.08
Median age at first event (years) 50.39 50.63 50.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
341
Matched controls
3409
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M71.5
ICD-10 Finland
Other bursitis, not elsewhere classified
+∞
242.7
203
*
7273A
ICD-9 Finland
Other disorders of synovium, tendon and bursa, Other bursitis
+∞
156.7
138
*
9473
FHL
Local soft tissue removal or exploration (eg Bursa)
278.3
48.3
48
*
NHL16
NOMESCO Finland
Tenolysis or tenosynovectomy of achilles tendon
330.1
30.3
30
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
5.2
26.9
93
228
M79.6
ICD-10 Finland
Pain in limb
4.0
26.4
130
452
M76.6
ICD-10 Finland
Achilles tendinitis
15.3
25.3
42
31
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.0
21.2
184
947
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
38.4
20.1
25
7
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
46.8
18.5
22
5
M79.0
ICD-10 Finland
Rheumatism, unspecified
70.5
17.9
20
*
NBG10
NOMESCO Finland
Acromioplastia
42.4
16.5
20
5
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
11.6
16.3
30
28
N02AX02
ATC
tramadol; systemic, rectal
2.7
16.2
158
829
M25.5
ICD-10 Finland
Pain in joint
3.0
15.3
106
445
N02AJ06
ATC
codeine and paracetamol; systemic
2.7
15.2
139
696
N03AX16
ATC
pregabalin; oral
3.1
14.7
91
354
M67.4
ICD-10 Finland
Ganglion
11.2
14.0
26
25
M01AH05
ATC
etoricoxib; oral
2.4
13.9
202
1276
M19.0
ICD-10 Finland
Primary arthrosis of other joints
5.1
13.5
43
93
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
29.7
13.1
17
6
M77.4
ICD-10 Finland
Metatarsalgia
6.9
11.0
27
42
M48.0
ICD-10 Finland
Spinal stenosis
3.7
11.0
49
147
S18
ICPC
Laceration/cut
2.2
11.0
147
860
H02AB06
ATC
prednisolone; systemic
2.2
10.7
170
1072
M02AA07
ATC
piroxicam; topical
2.3
10.7
131
733
R06.0
ICD-10 Finland
Dyspnoea
2.5
10.6
92
432
R52.9
ICD-10 Finland
Pain, unspecified
4.8
10.6
35
79
M70.6
ICD-10 Finland
Trochanteric bursitis
3.7
10.6
48
146
M54.4
ICD-10 Finland
Lumbago with sciatica
3.2
10.6
58
203
M01AB05
ATC
diclofenac; systemic, rectal
2.2
10.5
222
1574
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
113.4
10.5
11
*
J01DA09
ATC
[U] cefadroxil; inhalant, oral
2.4
10.2
109
566
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.9
9.9
66
264
NBG00
NOMESCO Finland
Plastic operation on acromioclavicular joint
56.6
9.7
11
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.4
9.3
46
150
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
19.2
9.0
13
7
M01AX17
ATC
nimesulide; oral
2.3
9.0
94
480
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
3.0
8.9
51
186
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.9
8.8
35
96
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.7
8.7
63
264
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.1
8.6
132
798
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
6.7
8.6
21
33
M03BX02
ATC
tizanidine; oral
2.0
8.5
203
1454
M79.1
ICD-10 Finland
Myalgia
3.5
8.5
40
126
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
92.2
8.5
9
*
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
92.2
8.5
9
*
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
8.4
93
486
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.4
8.3
74
349
ZXA00
NOMESCO Finland
Right side
2.2
8.3
94
498
N03AX12
ATC
gabapentin; oral
2.8
8.1
53
208
M01AC06
ATC
meloxicam; systemic, rectal
2.0
7.7
123
749
M01AH01
ATC
celecoxib; oral (coxibs)
2.4
7.6
67
312
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.5
7.4
33
100
Z50.1
ICD-10 Finland
Other physical therapy
4.5
7.4
25
59
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.1
7.4
41
145
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.8
7.3
46
177
L08
ICPC
Shoulder symptom/complaint
2.5
7.3
58
255
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
7.3
96
539
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
6.1
7.0
18
31
M79.7
ICD-10 Finland
Fibromyalgia
17.1
6.8
10
6
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
17.1
6.8
10
6
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
6.8
40
149
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
6.7
71
362
R03AC02
ATC
salbutamol; inhalant
1.8
6.5
165
1165
A02BC02
ATC
pantoprazole; systemic
1.8
6.4
208
1586
X59
ICD-10 Finland
Exposure to unspecified factor
2.3
6.4
62
302
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.8
6.4
20
44
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
3.4
6.4
29
90
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
11.3
6.3
11
10
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
6.3
105
641
M01AE03
ATC
ketoprofen; systemic, rectal
1.9
6.3
121
778
9476
FHL
Splitting of fascia or aponeurosis
+∞
6.3
6
*
NBL22
NOMESCO Finland
Myotomy, tenotomy or excision of tendon of upper arm
27.2
6.3
8
*
H02.3
ICD-10 Finland
Blepharochalasis
3.8
6.2
25
70
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
6.2
59
287
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.7
6.2
40
158
M54.5
ICD-10 Finland
Low back pain
1.9
6.2
95
564
M77.0
ICD-10 Finland
Medial epicondylitis
12.8
6.1
10
8
SPAT1153
SPAT
Removal of sutures
1.9
6.1
102
624
M01AH02
ATC
rofecoxib; oral
2.5
6.0
46
200
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.9
6.0
23
62
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.2
6.0
21
52

Mortality – FinRegistry

Association

Association between endpoint M13_BURSITISOTH and mortality.

Females

Parameter HR [95% CI] p-value
M13_BURSITISOTH 1.001 [0.75, 1.33] 0.996
Birth year 0.994 [0.99, 1.0] 0.137

During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 679 females with M13_BURSITISOTH died.

Males

Parameter HR [95% CI] p-value
M13_BURSITISOTH 0.81 [0.61, 1.07] 0.136
Birth year 0.99 [0.98, 1.0] 0.037

During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 570 males with M13_BURSITISOTH died.

Mortality risk

Mortality risk for people of age

years, who have M13_BURSITISOTH.

N-year risk Females Males
1 0.111% 0.188%
5 0.535% 1.046%
10 1.395% 2.788%
15 2.757% 5.075%
20 4.987% 8.741%

Relationships between endpoints

Index endpoint: M13_BURSITISOTH – Other bursitis, not elsewhere classified

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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