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COPD related to chronic (opportunist) infections

EFO MESH Endpoint Browser PheWeb

COPD_OPPORTUNIST_INFECTIONS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

  • J10_COPDNAS
24941

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

895

6. Filter based on genotype QC (FinnGen only)

872

Control definitions (FinnGen only)

Control conditions
not J10_COPDNAS

Extra metadata

First used in FinnGen datafreeze
DF3

Case counts by codes

↥

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5779 2148 3513
Only index persons 4088 1704 2384
Unadjusted period prevalence (%)
Whole population 0.09 0.06 0.10
Only index persons 0.08 0.06 0.09
Median age at first event (years)
Whole population 66.31 65.05 67.09
Only index persons 66.29 65.07 67.17

-FinnGen-

Key figures

All Female Male
Number of individuals 872 310 562
Unadjusted period prevalence (%) 0.21 0.11 0.26
Median age at first event (years) 67.26 62.82 69.71

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
895
Matched controls
8950
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J45.9
ICD-10 Finland
Asthma, unspecified
11.9
318.1
494
838
J01MA14
ATC
moxifloxacin; systemic
13.9
307.9
356
406
UGC12
NOMESCO Finland
Flexible bronchoscopy
14.4
307.7
372
421
R03AK06
ATC
salmeterol and fluticasone; inhalant
22.5
307.7
537
559
R03AK03
ATC
[U] fenoterol and ipratropium bromide
21.6
307.7
283
188
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
53.5
307.7
197
47
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
706.5
307.7
762
72
J47
ICD-10 Finland
Bronchiectasis
591.0
307.7
731
67
R03BB04
ATC
tiotropium bromide; inhalant
72.0
307.7
639
300
R03DA04
ATC
theophylline; systemic, rectal
27.1
307.7
335
193
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
25.2
307.7
638
804
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
176.6
307.7
304
26
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
497.1
307.7
460
19
R03AC12
ATC
salmeterol; inhalant
22.8
306.3
244
145
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
645.0
291.2
273
6
J45.1
ICD-10 Finland
Nonallergic asthma
15.8
285.2
284
255
R95
ICPC
Chron obstructive pulmonary disease
54.7
280.5
162
36
J18.9
ICD-10 Finland
Pneumonia, unspecified
11.8
274.7
681
1907
J96.1
ICD-10 Finland
Chronic respiratory failure
45.1
264.6
160
43
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
17.1
262.7
243
191
R03BB01
ATC
ipratropium bromide; inhalant
17.7
249.7
224
166
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
10.0
235.4
350
541
H02AB06
ATC
prednisolone; systemic
14.6
230.3
783
2898
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
9.7
228.2
347
549
R03AC02
ATC
salbutamol; inhalant
14.3
224.7
784
2954
J46
ICD-10 Finland
Status asthmaticus
34.4
215.1
140
48
R03BA05
ATC
fluticasone; inhalant
8.1
205.2
385
762
R03DC03
ATC
montelukast; oral
8.2
192.4
333
600
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
44.0
185.7
112
29
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
100.0
173.2
90
10
J45.8
ICD-10 Finland
Mixed asthma
22.2
169.9
130
68
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
58.2
166.3
94
18
J45.0
ICD-10 Finland
Predominantly allergic asthma
9.9
159.8
210
270
R03BA01
ATC
beclometasone; inhalant
7.3
159.2
300
581
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
6.3
158.7
387
962
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
15.4
148.3
137
104
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
250.8
146.8
147
7
J01MA12
ATC
levofloxacin; systemic
5.6
142.6
412
1174
R03AC13
ATC
formoterol; inhalant
11.5
142.4
161
168
R03BA02
ATC
budesonide; inhalant
6.2
142.0
330
775
R03AK07
ATC
formoterol and budesonide; inhalant
6.2
139.6
320
741
H02AB07
ATC
prednisone; oral
6.3
139.3
310
698
J43.9
ICD-10 Finland
Emphysema, unspecified
26.1
135.6
96
41
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
34.7
132.6
85
27
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
10.1
130.6
163
194
R03AK08
ATC
formoterol and beclometasone; inhalant
12.7
124.0
128
116
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
5.4
122.1
641
2863
R04.2
ICD-10 Finland
Haemoptysis
11.0
121.6
140
149
XG410
NOMESCO Finland
Flow-volume spirometry
10.7
116.6
136
147
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
25.3
116.3
83
36
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
12.6
114.0
118
107
R03AC03
ATC
terbutaline; inhalant
5.9
111.0
246
542
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
7.7
110.9
174
271
H02AB04
ATC
methylprednisolone; systemic
5.3
106.7
275
690
GD1AD
NOMESCO Finland
Thorax CT examination
7.5
105.2
170
273
J01FA06
ATC
roxithromycin; oral
4.3
99.2
542
2374
J42
ICD-10 Finland
Unspecified chronic bronchitis
25.5
87.6
62
26
R02
ICPC
Shortness of breath/dyspnoea
4.8
87.2
248
665
TGC00
NOMESCO Finland
Bronchial lavation
10.0
83.5
100
111
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
8.3
83.2
117
159
J45
ICD-10 Finland
Asthma
5.8
83.1
174
358
R06.0
ICD-10 Finland
Dyspnoea
3.7
81.7
419
1703
J01FA09
ATC
clarithromycin; systemic
3.8
79.3
376
1446
J01AA02
ATC
doxycycline; systemic
7.9
77.4
828
5452
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.7
73.1
625
3436
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
36.4
71.5
45
13
R03AK11
ATC
formoterol and fluticasone; inhalant
11.6
71.4
76
71
51899
ICD-8 Finland
Bronchiectasis
198.4
71.2
73
*
XG466
NOMESCO Finland
Sleep oxymetry
9.6
71.1
87
99
R05CB01
ATC
acetylcysteine; inhalant, oral
14.3
68.8
64
48
R96
ICPC
Asthma
5.0
68.0
169
401
C03CA01
ATC
furosemide; systemic
3.3
66.3
526
2706
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.1
64.9
155
355
R81
ICPC
Pneumonia
7.4
64.8
99
147
J01FA15
ATC
telithromycin; oral
5.0
64.5
157
365
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.6
64.3
295
1088
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
23.1
60.0
44
20
R03DC01
ATC
zafirlukast; oral
13.8
59.3
56
43
R03BA08
ATC
ciclesonide; inhalant
5.0
59.2
140
317
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
+∞
59.0
56
*
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
5.6
58.1
120
241
4940A
ICD-9 Finland
Bronchiectasis[BRONCHIECTASIAE]
130.7
57.6
61
5
J20
ICD-10 Finland
Acute bronchitis
4.4
57.1
163
429
J01FA10
ATC
azithromycin; systemic
3.0
55.9
527
2895
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
14.0
52.3
49
37
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
6.9
52.0
84
132
R28
ICPC
Limited function/disability (R)
13.2
51.6
50
40
XG474
NOMESCO Finland
Exhalation nntrogen oxide
9.2
48.4
60
69
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
8.3
47.8
65
84
A07AA02
ATC
nystatin; oral
4.7
47.0
119
283
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.5
47.0
191
639
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
7.0
46.6
74
114
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
4.8
45.9
111
254
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
14.9
44.4
40
28
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
7.7
42.8
62
86
A01AB09
ATC
miconazole; local oral
3.8
42.1
144
428
49300
ICD-8 Finland
Asthma, bronchiale
7.2
41.2
63
93
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.7
40.4
314
1501
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
13.1
40.3
39
31
XG405
NOMESCO Finland
Education on PEF monitoring
12.7
39.5
39
32
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
38.8
412
2276
I50.9
ICD-10 Finland
Heart failure, unspecified
2.8
38.6
260
1152
J15.8
ICD-10 Finland
Other bacterial pneumonia
15.3
38.4
34
23
J01CA04
ATC
amoxicillin; systemic
3.1
37.4
741
5448
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.6
36.2
290
1394
M05BA04
ATC
alendronic acid; oral
3.4
35.7
142
464
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
6.4
34.8
59
97
R05
ICPC
Cough
2.6
34.7
261
1213
348
Kela drug reimbursment
Roflumilast
+∞
34.6
33
*
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
+∞
34.6
33
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.7
33.8
65
121
J96.0
ICD-10 Finland
Acute respiratory failure
9.7
33.8
40
43
WW200
NOMESCO Finland
Immunization
7.4
33.8
50
71
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
33.2
241
1099
A02BC02
ATC
pantoprazole; systemic
2.5
32.0
665
4787
R03AL11
ATC
formoterol, glycopyrronium bromide and budesonide; inhalant
171.1
31.9
33
*
R01AD08
ATC
fluticasone; nasal
2.5
31.4
266
1300
WX725
NOMESCO Finland
Noninvasive ventilation
4.3
31.3
85
212
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
30.8
273
1361
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
9.8
30.8
36
38
A03
ICPC
Fever
3.0
30.6
156
589
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.3
30.6
351
1958
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
12.4
30.0
30
25
J01DA08
ATC
[U] cefaclor
3.8
29.4
98
284
R03DX07
ATC
roflumilast; oral
+∞
29.3
28
*
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
6.6
29.3
48
76
J01GB01
ATC
tobramycin; inhalant, parenteral
301.3
28.9
29
*
R03AC18
ATC
indacaterol; inhalant
45.4
28.9
35
8
R5140
NOMESCO Finland
Monitoring the use of the aid
2.9
28.0
149
574
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
27.2
337
1919
A02BC05
ATC
esomeprazole; systemic
2.2
27.2
406
2489
A02BC03
ATC
lansoprazole; oral
2.2
26.8
329
1864
R01AD09
ATC
mometasone; nasal
2.2
26.7
384
2316
J41.1
ICD-10 Finland
Mucopurulent chronic bronchitis
47.3
26.6
32
7
J01DA06
ATC
[U] cefuroxime
2.7
26.3
166
699
N07BA03
ATC
varenicline; oral
5.9
26.2
48
85
R03AL04
ATC
indacaterol and glycopyrronium bromide; inhalant
62.0
26.1
30
5
Z3226
NOMESCO Finland
Physiotherapist
2.4
25.1
217
1057
49104
ICD-8 Finland
Chronic bronchitis, Cum emphysemate
+∞
25.1
24
*
J01MA02
ATC
ciprofloxacin; systemic
2.1
25.1
436
2805
R06.2
ICD-10 Finland
Wheezing
4.7
24.6
58
129
J15.1
ICD-10 Finland
Pneumonia due to Pseudomonas
49.8
24.4
29
6
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.8
23.9
56
124
R06AE07
ATC
cetirizine; oral
2.1
23.8
362
2205
R05
ICD-10 Finland
Cough
2.3
23.7
216
1074
J01DB01
ATC
cefalexin; oral
2.4
23.7
728
5757
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.0
23.4
52
110
N02AX02
ATC
tramadol; systemic, rectal
2.0
23.2
439
2887
J01DA01
ATC
[U] cefalexin
2.1
23.1
580
4215
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
4.2
22.9
64
163
SPAT1254
SPAT
Administration of medicine
2.4
22.6
192
925
R01AD01
ATC
beclometasone; nasal
2.6
22.5
155
678
R05DA20
ATC
opium alkaloids and derivatives - combinations
2.2
22.4
258
1409
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
4.3
22.4
60
148
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.4
22.3
85
268
R29
ICPC
Respiratory symptom/complaint other
3.5
22.3
82
253
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
7.5
22.2
32
44
R03BB02
ATC
oxitropium bromide; inhalant
17.6
21.9
34
20
J01DC02
ATC
cefuroxime; systemic
3.9
21.6
66
179
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
21.5
167
771
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.3
21.5
88
290
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
7.7
21.3
30
40
C07AB07
ATC
bisoprolol; oral
2.0
21.3
552
4005
I50.0
ICD-10 Finland
Congestive heart failure
2.7
21.0
130
538
A02BA02
ATC
ranitidine; systemic
2.2
21.0
238
1288
Z72.0
ICD-10 Finland
Tobacco use
7.0
20.9
32
47
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.4
20.9
80
253
Z2446
NOMESCO Finland
Social worker
3.3
20.5
81
261
A02BC01
ATC
omeprazole; systemic
2.0
20.2
297
1765
R50.9
ICD-10 Finland
Fever, unspecified
2.3
20.1
175
849
N02AA05
ATC
oxycodone; systemic
2.1
19.8
236
1298
R03BB07
ATC
umeclidinium bromide; inhalant
25.2
19.6
27
11
J31.0
ICD-10 Finland
Chronic rhinitis
3.1
19.6
87
301
Z3231
NOMESCO Finland
Registered nurse
2.0
19.4
289
1721
XG460
NOMESCO Finland
Short time oxymetry
5.9
19.4
35
61
H02AB09
ATC
hydrocortisone; systemic
5.0
19.4
42
87
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
19.1
187
951
R78
ICPC
Acute bronchitis/bronchiolitis
5.1
18.9
40
81
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
28.5
18.8
25
9
N05CF01
ATC
zopiclone; oral
1.9
18.7
341
2171
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
18.7
229
1269
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
102.2
18.6
20
*
F17.20
ICD-10 Finland
Addiction relationship caused by tobacco addiction relationship currently independent
39.3
18.6
23
6
J02AC01
ATC
fluconazole; systemic
2.0
18.6
287
1728
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.1
18.4
82
284
WX892
NOMESCO Finland
Monitored bed care
2.8
18.4
101
393
A01AB10
ATC
natamycin; local oral
4.5
18.2
45
104
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
4.8
17.9
41
89
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
17.8
175
888
E88.0
ICD-10 Finland
Disorders of plasma-protein metabolism, not elsewhere classified
97.0
17.6
19
*
J43.8
ICD-10 Finland
Other emphysema
24.6
17.4
24
10
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
17.4
160
791
R05FB02
ATC
cough suppressants and expectorants; systemic
1.8
17.2
374
2503
M05BB03
ATC
alendronic acid and colecalciferol; oral
4.6
17.2
41
92
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.2
17.0
46
114
N03AX16
ATC
[U] pregabalin
2.0
16.9
230
1319
A01AB04
ATC
amphotericin B; local oral
3.2
16.8
68
222
R03BB06
ATC
glycopyrronium bromide; inhalant
35.8
16.7
21
6
R01AD58
ATC
fluticasone, combinations; nasal
2.2
16.7
159
796
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
16.6
141
673
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
6.3
16.5
28
46
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
30.7
16.2
21
7
49109
ICD-8 Finland
Chronic bronchitis, Unspecified
30.7
16.2
21
7
R74
ICPC
Upper respiratory infection acute
2.0
16.2
198
1091
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
4.5
16.0
39
89
J37.0
ICD-10 Finland
Chronic laryngitis
4.0
15.8
45
116
J01FF01
ATC
clindamycin; systemic
1.9
15.7
256
1554
1240
FHL
Bronchoscopy
5.4
15.7
31
59
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
5.7
15.6
29
52
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.4
15.6
56
170
R01BA52
ATC
pseudoephedrine, combinations; oral
1.9
15.5
246
1479
R4110
NOMESCO Finland
Physiotherapy
1.9
15.5
270
1675
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
12.6
15.4
27
22
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
11.5
15.3
28
25
XQ800
NOMESCO Finland
Prick test
3.2
15.2
61
198
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
15.2
145
724
R03DA54
ATC
theophylline, combinations excl. psycholeptics; systemic
6.4
15.1
25
40
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
14.9
222
1305
A28
ICPC
Limited function/disability NOS
1.9
14.9
230
1369
J01DA09
ATC
[U] cefadroxil
1.9
14.7
234
1406
G47.3
ICD-10 Finland
Sleep apnoea
2.0
14.6
203
1166
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.9
14.6
43
114
R60.0
ICD-10 Finland
Localized oedema
2.2
14.5
141
709
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.9
14.3
69
250
WZC30
NOMESCO Finland
Teaching
2.1
14.2
160
852
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.5
14.1
97
420
N06AB04
ATC
citalopram; systemic
2.0
14.1
188
1062
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
13.9
284
1839
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.1
13.9
58
193
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
11.7
13.8
25
22
A31.9
ICD-10 Finland
Mycobacterial infection, unspecified
54.2
13.8
16
*
R01AD05
ATC
budesonide; nasal
2.7
13.8
77
301
J43.2
ICD-10 Finland
Centrilobular emphysema
24.2
13.8
19
8
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
76.3
13.6
15
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
13.6
120
580
A02BA03
ATC
famotidine; systemic
3.1
13.6
58
196
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
4.0
13.5
39
102
SPAT1263
SPAT
Sampling
1.7
13.4
373
2632
R99
ICPC
Respiratory disease other
5.0
13.4
29
60
L04AX01
ATC
azathioprine; systemic
3.7
13.4
43
121
A46
ICD-10 Finland
Erysipelas
2.0
13.4
163
892
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.1
13.2
55
183
L28
ICPC
Limited function/disability (L)
1.9
13.1
212
1274
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
13.1
161
882
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
13.1
316
2141
R03CC02
ATC
salbutamol; systemic
4.3
13.1
34
82
J02AC03
ATC
voriconazole; systemic
22.9
12.9
18
8
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
22.9
12.9
18
8
XF600
NOMESCO Finland
Bloodpressure measurement
2.6
12.9
78
318
R05CB03
ATC
carbocisteine; oral
4.0
12.8
36
92
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.9
12.8
62
225
SPAT1325
SPAT
Vaccination
1.7
12.7
354
2489
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
3.7
12.7
40
111
R03BB05
ATC
aclidinium bromide; inhalant
32.5
12.6
16
5
S81.0
ICD-10 Finland
Open wound of knee
5.3
12.5
25
48
SPAT1059
SPAT
Spirometry at the office
2.9
12.4
60
218
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
4.3
12.3
32
77
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.9
12.3
57
202
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.1
12.2
33
82
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.6
12.2
71
284
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
5.6
12.2
23
42
R05FA02
ATC
opium derivatives and expectorants; systemic
1.7
12.1
353
2504
WX722
NOMESCO Finland
PEEP
2.8
12.0
62
233
C03DA01
ATC
spironolactone; oral
2.0
11.9
144
784
P01AB01
ATC
metronidazole; oral, rectal
1.7
11.8
315
2179
48509
ICD-8 Finland
Bronchopneumonia, unspecified
10.7
11.8
22
21
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.4
11.7
83
364
T08
ICPC
Weight loss
4.7
11.7
27
59
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
30.5
11.7
15
5
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
65.8
11.6
13
*
C08DA01
ATC
verapamil; systemic
2.8
11.6
59
220
J43.1
ICD-10 Finland
Panlobular emphysema
+∞
11.5
11
*
49102
ICD-8 Finland
Chronic bronchitis, Purulenta
+∞
11.5
11
*
B44.8
ICD-10 Finland
Other forms of aspergillosis
121.5
11.4
12
*
J01XB01
ATC
colistin; inhalant, parenteral
121.5
11.4
12
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
11.4
100
482
A06AD11
ATC
lactulose; oral
1.8
11.4
186
1118
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.0
11.4
50
172
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
10.7
11.3
21
20
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
11.3
283
1923
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
5.3
11.1
22
42
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.0
11.1
132
714
J86.9
ICD-10 Finland
Pyothorax without fistula
5.8
11.0
20
35
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
14.1
11.0
18
13
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.7
10.9
58
221
F2680, ,
NOMESCO Finland
43.9
10.9
13
*
N06AA09
ATC
amitriptyline; systemic
2.2
10.9
94
449
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
12.1
10.9
19
16
RK320, ,
NOMESCO Finland
8.4
10.9
23
28
B02AA02
ATC
tranexamic acid; systemic
2.1
10.8
104
519
R03BC03
ATC
nedocromil; inhalant
2.5
10.8
70
295
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
10.8
404
3028
R04
ICPC
Breathing problem other
3.2
10.6
42
136
ZXD05
NOMESCO Finland
Urgent procedure
1.7
10.6
271
1846
R63.4
ICD-10 Finland
Abnormal weight loss
2.9
10.5
48
169
R03AL05
ATC
formoterol and aclidinium bromide; inhalant
111.3
10.4
11
*
49099
ICD-8 Finland
Bronchitis, unspecified
7.8
10.4
23
30
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.9
10.4
50
181
SPAT1255
SPAT
Intravenous administration of medicine
2.3
10.4
79
358
A08
ICPC
Swelling
2.5
10.3
65
270
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
4.5
10.3
25
57
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
10.3
246
1643
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
9.7
10.3
20
21
N05BA01
ATC
diazepam; systemic, rectal
2.0
10.2
125
681
J01DC04
ATC
cefaclor; oral
8.0
10.1
22
28
J33.0
ICD-10 Finland
Polyp of nasal cavity
3.3
10.1
37
114
Z2221
NOMESCO Finland
Medical doctor
1.7
10.1
240
1601
4931A
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA SINE EXACERBATIONE]
9.3
10.0
20
22
J98.1
ICD-10 Finland
Pulmonary collapse
10.2
10.0
19
19
N03AX12
ATC
[U] gabapentin; oral
1.8
10.0
154
905
49101
ICD-8 Finland
Chronic bronchitis, Nonpurulenta (simplex)
14.8
10.0
16
11
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
3.9
10.0
29
76
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.4
9.9
35
105
ZX120
NOMESCO Finland
Intravenous
2.1
9.9
101
515
J98.0
ICD-10 Finland
Diseases of bronchus, not elsewhere classified
12.4
9.9
17
14
A02BA04
ATC
nizatidine; systemic
2.2
9.8
87
420
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
26.3
9.8
13
5
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
20.3
9.8
14
7
120
Kela drug reimbursment
Hypogammaglobulinaemia
20.3
9.8
14
7
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
9.8
171
1044
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.9
9.8
141
811
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
9.7
174
1070
4900A
ICD-9 Finland
Bronchitis, not specified as acute or chronic[BRONCHITIS NUD]
13.5
9.7
16
12
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.5
9.6
59
242
R01AD11
ATC
triamcinolone; nasal
2.3
9.6
71
318
SPAT1257
SPAT
Teaching of medicine inhalation technique
3.0
9.6
43
150
B37.0
ICD-10 Finland
Candidal stomatitis
9.2
9.6
19
21
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
9.5
96
488
TPH07
NOMESCO Finland
Cathetrisation of artery
1.9
9.4
119
655
R03AC19
ATC
olodaterol
30.4
9.4
12
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
9.4
159
962
RK110, ,
NOMESCO Finland
8.2
9.4
20
25
6BA02, ,
NOMESCO Finland
22.0
9.4
13
6
J61
ICD-10 Finland
Pneumoconiosis due to asbestos and other mineral fibres
7.0
9.4
22
32
N02BE01
ATC
paracetamol; systemic, rectal
1.8
9.3
758
6742
R24
ICPC
Haemoptysis
8.8
9.3
19
22
RK250, ,
NOMESCO Finland
9.6
9.3
18
19
WX882
NOMESCO Finland
High dependency care
3.2
9.3
36
115
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
9.3
87
430
N06AX11
ATC
mirtazapine; oral
1.6
9.2
272
1908
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
13.8
9.2
15
11
J20.0
ICD-10 Finland
Acute bronchitis due to Mycoplasma pneumoniae
7.8
9.2
20
26
R03DA05
ATC
aminophylline; systemic, rectal
7.8
9.2
20
26
J01MA01
ATC
ofloxacin; systemic
2.0
9.1
98
510
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.0
8.9
39
134
R03AC04
ATC
fenoterol; inhalant
12.7
8.9
15
12
78310
ICD-8 Finland
Symptoms referable to respiratory system, Haemoptysis
12.7
8.9
15
12
R05CA10
ATC
expectorants - combinations
3.6
8.7
28
79
N02AA01
ATC
morphine; systemic, rectal
3.3
8.7
32
99
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
8.7
95
498
M05BX04
ATC
denosumab; parenteral
2.2
8.6
70
326
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
4.8
8.6
19
40
R06AE09
ATC
levocetirizine; oral
2.0
8.6
99
528
R79
ICPC
Chronic bronchitis
16.5
8.6
13
8
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
9.1
8.6
17
19
M05BA07
ATC
risedronic acid; oral
3.0
8.5
38
132
N05CD07
ATC
temazepam; oral
1.8
8.5
134
792
ZXA10
NOMESCO Finland
Bilateral
1.7
8.5
191
1249
P03
ICPC
Feeling depressed
2.5
8.5
52
214
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
8.4
81
404
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.8
8.4
43
161
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
90.9
8.4
9
*
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
90.9
8.4
9
*
B44.0
ICD-10 Finland
Invasive pulmonary aspergillosis
90.9
8.4
9
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
8.4
97
518
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.9
8.4
115
651
R06AX13
ATC
loratadine; oral
1.9
8.4
102
555
R11
ICD-10 Finland
Nausea and vomiting
2.1
8.3
79
392
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.5
8.3
51
210
UJF32
NOMESCO Finland
Coloscopy
1.6
8.3
252
1775
N05BA04
ATC
oxazepam; oral
1.6
8.2
217
1476
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.2
8.2
68
320
ZXE00
NOMESCO Finland
One hour or less
1.5
8.2
324
2420
J32.4
ICD-10 Finland
Chronic pansinusitis
4.6
8.1
19
42
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
3.4
8.1
29
88
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.6
8.1
48
194
R01AD12
ATC
fluticasone furoate; nasal
1.7
8.0
187
1231
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
8.0
300
2209
Q32.21
ICD-10 Finland
Secondary congenital bronchomalacia
22.2
8.0
11
5
A01
ICPC
Pain general/multiple sites
2.0
8.0
89
469
R05CB02
ATC
bromhexine; systemic
3.8
7.9
24
65
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
7.9
281
2044
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
7.9
110
625
R03AK
ATC
Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics
13.2
7.9
13
10
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.0
7.9
83
429
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
7.8
132
795
SPAT1060
SPAT
Administration of oxygen
10.9
7.8
14
13
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
7.8
140
859
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.0
7.8
80
410
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.4
7.7
54
237
JN4BD
NOMESCO Finland
Extensive body CT
1.8
7.6
115
671
WX721
NOMESCO Finland
Oxygen concentrator therapy
25.2
7.6
10
*
J01MA11
ATC
grepafloxacin; oral
25.2
7.6
10
*
C01DA14
ATC
isosorbide mononitrate; oral
1.6
7.6
217
1502
P17
ICPC
Tobacco abuse
9.0
7.6
15
17
I20.90
ICD-10 Finland
Angina pectoris, unspecified
2.3
7.6
55
245
4931B
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA CUM EXACERBATIONE]
10.1
7.5
14
14
AA1AD
NOMESCO Finland
CT of head and brain
1.5
7.5
279
2045
JN4AD
NOMESCO Finland
Body CT examination
1.8
7.5
107
612
J18
ICD-10 Finland
Pneumonia, organism unspecified
6.5
7.4
18
28
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
6.5
7.4
18
28
B05XA03
ATC
sodium chloride; parenteral
80.7
7.4
8
*
C08DB01
ATC
diltiazem; oral
2.1
7.4
71
354
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
13.5
7.4
12
9
UDM02
NOMESCO Finland
Sinoscopy
3.8
7.4
22
59
R83
ICPC
Respiratory infection other
1.8
7.4
124
746
C01AA05
ATC
digoxin; systemic
1.8
7.4
114
669
J92.9
ICD-10 Finland
Pleural plaque without asbestos
4.1
7.4
20
50
N05BA02
ATC
chlordiazepoxide; systemic
3.2
7.3
28
89
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
9.5
7.3
14
15
A41.9
ICD-10 Finland
Sepsis, unspecified
2.5
7.3
44
180
R13
ICD-10 Finland
Dysphagia
2.0
7.2
73
372
C02DE01, ,
ATC
4.0
7.2
20
51
F1246, ,
NOMESCO Finland
30.3
7.2
9
*
J98.9
ICD-10 Finland
Respiratory disorder, unspecified
30.3
7.2
9
*
4919X
ICD-9 Finland
Chronic bronchitis, Unspecified chronic bronchitis
20.2
7.1
10
5
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.6
7.1
17
26
RF220, ,
NOMESCO Finland
3.8
7.1
21
56
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
3.1
7.1
29
96
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
10.1
7.0
13
13
M54.5
ICD-10 Finland
Low back pain
1.5
7.0
265
1945
R4190
NOMESCO Finland
Nutritional therapy
2.9
7.0
32
113
R06AX22
ATC
ebastine; oral
1.8
7.0
112
664
S97
ICPC
Chronic ulcer skin
2.0
7.0
71
362
B01AA03
ATC
warfarin; systemic
1.5
7.0
242
1745
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
5.5
6.9
19
35
J41.0
ICD-10 Finland
Simple chronic bronchitis
7.6
6.9
15
20
GX2D5
NOMESCO Finland
Sleep oximetry
13.9
6.9
11
8
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.2
6.9
26
82
L95
ICPC
Osteoporosis
2.6
6.8
40
161
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
3.1
6.8
28
93
M81.4
ICD-10 Finland
Drug-induced osteoporosis
11.0
6.8
12
11
UJD02
NOMESCO Finland
Gastroscopy
2.2
6.8
54
250
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.2
6.8
54
250
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.8
6.8
33
121
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
6.8
346
2697
R23.3
ICD-10 Finland
Spontaneous ecchymoses
3.2
6.8
26
83
RS230, ,
NOMESCO Finland
16.8
6.8
10
6
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
3.3
6.7
25
78
ZY010
NOMESCO Finland
Hospital outpatient
2.7
6.7
34
127
N06AB10
ATC
escitalopram; oral
1.7
6.7
122
751
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
6.7
90
506
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.5
6.7
40
163
B96.5
ICD-10 Finland
Pseudomonas (aeruginosa) as the cause of diseases classified to other chapters
22.7
6.7
9
*
A16.0
ICD-10 Finland
Tuberculosis of lung, bacteriologically and histologically negative
22.7
6.7
9
*
R06AX27
ATC
desloratadine; oral
1.6
6.7
159
1050
48609
ICD-8 Finland
Pneumonia, unspecified
5.5
6.6
18
33
A04
ICPC
Weakness/tiredness general
1.7
6.6
134
849
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
6.6
256
1887
P01BA02
ATC
hydroxychloroquine; oral
2.0
6.6
66
335
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.2
6.6
57
274
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.5
6.5
41
171
SPAT1172
SPAT
Guidance concerning hydration
2.9
6.5
29
101
D07AA02
ATC
hydrocortisone; topical
1.8
6.5
102
601
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.0
6.5
72
379
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
6.5
68
351
B01AC04
ATC
clopidogrel; oral
1.6
6.4
191
1330
R03BC01
ATC
cromoglicic acid; inhalant
5.2
6.3
18
35
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
3.6
6.3
20
56
H25.1
ICD-10 Finland
Senile nuclear cataract
1.4
6.3
329
2564
L14
ICPC
Leg/thigh symptom/complaint
1.9
6.3
74
398
J20.8
ICD-10 Finland
Acute bronchitis due to other specified organisms
18.2
6.3
9
5
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.2
6.2
49
226
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
26.9
6.2
8
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.2
6.2
52
246
UKC02
NOMESCO Finland
Cystoscopy
1.5
6.2
187
1304
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.2
6.1
48
221
R53
ICD-10 Finland
Malaise and fatigue
1.5
6.1
202
1437
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
2.8
6.1
29
105
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.6
6.1
34
134
A02BX02
ATC
sucralfate; oral
2.3
6.1
44
196
4939A
ICD-9 Finland
Asthma, unspecified[ASTHMA ALIA DEFINITA SINE EXACERBATIONE]
8.7
6.1
12
14
4221
FHL
Polyp removal from the nasal cavity, sinus puncture or irrigation, or biopsy under general anesthesia or operating room
10.1
6.0
11
11
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
6.1
6.0
15
25
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.8
6.0
29
106

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
275
115
34.08
307.65
5.6
2.4
—
—
—
0
0
106
35
34.22
163.93
1.9
1.2
1.98
1.02
u/ml
0.41
86
22
187
286
8.00
121.63
2.0
1.2
336.72
160.32
u/ml
2.51
174
258
117
126
10.53
100.24
6.9
2.3
—
—
—
0
0
265
819
4.18
76.38
2.8
1.4
—
—
—
0
0
63
43
15.68
71.38
1.5
1.3
2.70
2.55
g/l
0.18
41
31
63
43
15.68
71.38
1.5
1.3
7.09
7.05
g/l
0.02
44
31
63
43
15.68
71.38
1.5
1.3
0.45
0.41
g/l
0.19
44
30
62
44
15.07
68.75
1.6
1.3
—
—
—
0
0
165
395
4.90
65.53
7.0
10.5
25.32
24.33
mmol/l
3.23
154
382
263
910
3.68
63.10
7.2
7.7
5.37
4.98
kpa
4.94
250
874
75
82
9.89
63.02
1.6
1.3
0.83
0.86
g/l
0.06
52
64
261
911
3.63
61.64
7.3
7.6
9.51
12.15
kpa
22.06
248
876
180
487
4.37
61.02
3.6
2.9
10.49
10.90
g/l
0.49
171
438
189
532
4.24
60.76
4.5
5.0
—
—
—
0
0
465
2314
3.10
60.45
7.6
4.2
—
—
—
0
0
170
447
4.46
59.75
1.8
1.4
—
—
—
0
0
258
917
3.55
58.96
7.3
7.6
2.17
1.00
mmol/l
4.18
215
722
178
502
4.18
56.85
7.7
3.5
5.49
5.05
kpa
5.82
169
475
176
495
4.18
56.39
7.5
3.5
7.41
7.40
ph
0.42
13
58
151
382
4.55
55.57
2.1
2.0
1.04
1.56
g/l
2.24
141
342
576
3349
3.02
54.53
10.8
5.2
0.04
0.04
e9/l
4.80
529
2846
575
3342
3.02
54.44
10.8
5.2
0.72
0.61
e9/l
18.90
527
2835
587
3453
3.03
54.30
11.1
5.4
0.20
0.20
e9/l
0.37
537
2984
550
3134
2.96
53.77
11.2
5.8
—
—
—
0
0
553
3166
2.95
53.49
12.0
5.8
8.57
8.98
%
2.35
538
2925
551
3162
2.93
52.81
11.5
5.4
2.55
2.87
%
2.38
535
2914
39
18
22.61
52.76
1.6
1.3
—
—
—
0
0
579
3413
2.97
52.74
10.8
5.3
1.79
1.91
e9/l
1.11
536
2967
551
3169
2.92
52.46
11.3
5.4
63.08
58.12
%
16.93
533
2936
539
3074
2.89
51.97
11.3
5.4
0.57
0.64
%
2.04
522
2835
554
3222
2.89
51.17
11.7
5.7
22.08
26.39
%
17.04
538
2978
162
484
3.87
47.24
2.2
1.5
—
—
—
0
0
138
368
4.25
47.09
7.9
3.6
—
—
—
0
0
265
1086
3.05
46.51
2.5
2.1
—
—
—
0
0
223
835
3.23
45.65
7.2
8.0
92.87
95.79
%
7.39
216
809
609
3933
2.72
42.32
13.1
8.7
5.62
4.16
e9/l
23.80
561
3407
41
36
11.89
39.82
1.5
2.5
686.54
535.94
e6/l
0.78
35
31
78
152
5.53
38.68
1.6
1.1
—
—
—
0
0
45
49
9.62
37.70
1.4
2.3
1.64
1.13
e9/l
2.19
39
44
195
832
2.72
30.38
2.3
1.7
—
—
—
0
0
432
2648
2.22
29.65
4.3
3.1
1825.16
1808.21
ng/l
0.03
394
2297
105
326
3.52
28.35
9.0
3.9
25.92
24.83
mmol/l
2.62
99
299
155
637
2.73
25.68
1.6
1.5
—
—
—
0
0
60
133
4.76
25.57
4.1
2.4
—
—
—
0
0
235
1191
2.32
24.81
4.1
3.2
0.81
0.82
mmol/l
0.16
219
1108
169
749
2.55
23.94
4.2
3.6
6.36
5.72
kpa
7.90
164
726
162
705
2.58
23.83
7.3
7.1
1.54
1.45
mmol/l
0.37
153
687
220
1109
2.30
23.36
2.0
1.5
2.87
2.64
g/l
1.00
166
622
165
738
2.52
22.86
4.3
3.6
3.59
1.83
mmol/l
5.62
153
599
257
1393
2.19
22.80
2.1
1.6
1.56
1.49
mg/l
0.07
212
1075
536
3834
1.99
21.75
8.5
6.4
9.93
12.40
umol/l
7.75
517
3634
151
668
2.52
21.32
8.2
8.4
—
—
—
0
0
128
533
2.64
20.44
4.8
3.7
1.92
0.62
%
0.86
48
196
57
152
3.94
19.13
7.9
4.1
—
—
—
0
0
472
3345
1.87
18.48
5.2
4.9
32.20
34.72
g/l
15.24
442
3101
126
555
2.48
17.81
5.0
4.1
0.07
0.10
%
0.28
45
194
132
595
2.43
17.74
5.0
4.0
1.29
0.88
%
0.49
52
233
106
432
2.65
17.59
10.5
11.2
—
—
—
0
0
520
3851
1.84
17.17
9.7
7.1
1.21
1.21
mmol/l
1.36
442
3238
487
3541
1.82
17.02
8.9
6.2
1.20
1.21
mmol/l
1.59
446
3184
92
366
2.69
15.98
2.5
1.8
1.10
2.62
ug/l
0.85
82
318
147
731
2.21
15.63
2.5
2.1
0.20
0.20
g/l
0.41
137
675
151
762
2.18
15.47
1.3
1.3
455.29
491.46
titre
0.13
34
171
116
527
2.38
15.24
5.2
4.0
0.11
0.64
%
0.49
35
166
111
496
2.41
15.13
9.2
9.5
91.36
94.39
%
3.75
111
496
516
3904
1.76
14.95
21.0
19.6
1.38
1.38
inr
0.01
148
1092
141
711
2.17
14.42
7.1
7.2
10.97
11.53
mmol/l
0.41
133
679
314
2079
1.79
14.36
2.7
2.2
3.44
3.05
mg/l
1.73
265
1747
149
769
2.12
14.35
3.7
3.0
284.81
240.38
ng/l
0.32
138
706
271
1725
1.82
14.09
9.5
6.5
—
—
—
0
0
628
5109
1.77
13.30
8.4
4.1
20.81
14.37
mm/h
12.65
590
4621
66
244
2.84
13.17
6.9
7.4
1.28
1.40
mmol/l
0.51
57
216
242
1516
1.82
13.12
7.1
4.1
150.94
299.20
ng/l
1.31
206
1305
51
169
3.14
12.33
10.4
4.4
3.06
2.78
mmol/l
0.30
44
110
25
49
5.22
12.26
1.4
1.1
—
—
—
0
0
208
1267
1.84
12.26
2.5
2.5
9.83
12.48
umol/l
6.10
187
1172
47
150
3.25
12.09
3.9
2.4
15.87
16.00
%
0.07
23
71
187
1106
1.87
12.08
2.7
2.6
18.15
22.70
%
4.31
165
930
417
3093
1.65
12.00
6.8
4.1
46.21
57.10
ng/l
0.43
335
2430
251
1650
1.72
11.28
3.5
3.1
510.30
555.48
mosm/kgh2o
3.36
223
1413
47
159
3.06
10.99
2.9
2.1
132.08
126.95
g/l
0.61
25
117
323
2284
1.65
10.96
3.2
2.5
52.24
96.64
u/l
0.68
298
2098
303
2110
1.66
10.91
4.1
3.1
32.37
34.90
u/l
0.37
288
2003
59
229
2.69
10.75
4.9
3.4
—
—
—
0
0
189
1160
1.80
10.73
2.6
2.5
2.14
2.24
g/l
1.59
174
1066
120
638
2.02
10.54
3.8
2.9
4.76
4.42
kpa
0.81
114
618
310
2191
1.63
10.43
4.4
3.4
0.66
0.52
e6/l
0.36
252
1711
585
4814
1.62
10.38
6.5
4.9
323.14
2579.90
e6/l
—
7
87
398
2992
1.59
10.36
17.1
9.9
0.00
0.00
e9/l
1.17
336
2435
268
1830
1.66
10.31
6.2
4.0
85.20
83.96
%
0.30
258
1789
20
38
5.36
10.15
1.6
3.3
—
—
—
0
0
649
5494
1.66
10.14
12.7
7.6
84.97
81.56
u/l
0.79
626
5101
376
2800
1.59
10.12
3.3
2.8
133.37
160.85
ug/l
1.73
339
2504
37
115
3.31
9.95
1.1
1.4
—
—
—
0
0
542
4403
1.59
9.94
8.5
4.9
6.75
6.87
mmol/l
0.76
521
4159
39
126
3.19
9.86
3.6
3.1
62.33
59.79
%
0.51
39
126
49
181
2.81
9.82
2.3
1.9
12.07
13.07
mg/l
0.31
44
163
294
2078
1.62
9.76
4.4
3.3
—
—
—
0
0
38
122
3.21
9.71
3.5
2.7
6.03
4.58
e9/l
1.78
38
122
368
2746
1.58
9.70
2.7
2.2
78.54
79.43
nmol/l
0.23
321
2358
326
2381
1.58
9.35
4.6
3.5
111.01
79.78
e6/l
0.31
267
1881
315
2295
1.57
9.07
5.2
4.1
7.40
7.40
ph
0.03
72
428
111
609
1.94
8.88
2.7
2.1
302.55
378.51
nmol/l
3.14
104
556
17
18
9.60
8.80
1.8
1.4
—
—
—
0
0
127
732
1.86
8.74
2.2
2.9
64.91
66.01
g/l
0.80
109
651
51
207
2.55
8.53
1.4
1.5
280.30
263.21
ug/g
0.24
30
119
167
1052
1.72
8.51
6.9
5.7
1.11
1.04
mmol/l
2.33
152
959
329
2462
1.53
8.22
3.8
3.4
—
—
—
0
0
110
619
1.89
8.15
2.0
2.7
—
—
—
0
0
65
305
2.22
7.89
1.9
3.7
134.37
75.97
mg/l
0.32
44
251
49
204
2.48
7.79
1.5
1.7
—
—
—
0
0
242
1715
1.56
7.63
3.4
2.7
4.79
4.52
e6/l
0.18
227
1548
350
2691
1.49
7.53
5.4
3.9
86.94
115.21
e6/l
0.34
280
2007
64
306
2.18
7.43
2.0
3.7
33.22
85.55
mg/l
0.71
44
254
160
1032
1.67
7.41
2.1
2.6
1.82
1.77
%
0.29
128
924
267
1946
1.53
7.39
3.6
3.0
4427.08
7321.22
umol/l
0.53
225
1646
187
1263
1.61
7.20
4.0
3.2
2.10
1.83
e6/l
0.28
96
731
29
97
3.06
6.98
4.5
4.9
—
—
—
0
0
18
44
4.15
6.84
1.1
1.1
0.30
0.82
u/ml
—
8
21
17
40
4.31
6.77
1.8
3.8
7.44
7.39
ph
—
7
11
22
63
3.55
6.74
1.3
1.7
—
—
—
0
0
570
4884
1.46
6.69
6.1
4.6
—
—
—
0
0
28
96
2.98
6.47
3.1
1.8
88.69
89.80
%
0.54
28
96
21
60
3.56
6.46
3.4
2.8
—
—
—
0
0
37
148
2.56
6.43
1.4
1.3
62.17
61.62
mmol/l
0.02
30
125
17
42
4.11
6.37
3.2
3.1
—
—
—
0
0
125
786
1.69
6.34
2.0
2.6
72.97
66.57
e9/l
1.23
89
626
16
27
6.01
6.32
3.4
1.6
55.11
53.13
ug/l
0.05
16
27
127
807
1.67
6.19
5.6
4.5
—
—
—
0
0
16
39
4.16
6.10
1.0
1.1
0.49
8.36
u/ml
—
5
16
179
1246
1.55
5.97
2.7
2.0
30.44
30.08
s
0.21
171
1206
145
963
1.60
5.92
1.4
1.2
—
—
—
0
0
145
964
1.60
5.89
1.3
1.2
57.02
38.71
iu/ml
0.34
51
293
47
220
2.20
5.79
1.8
4.1
—
—
—
0
0
17
35
4.93
5.76
2.9
1.9
700.00
1898.51
u/ml
0.94
17
35
122
783
1.65
5.71
3.4
2.6
5.81
6.58
ug/l
0.28
97
678
74
413
1.86
5.64
4.9
3.3
27.25
24.88
mmol/l
3.43
74
398
20
61
3.33
5.61
1.3
1.2
—
—
—
0
0
39
171
2.34
5.60
2.5
2.7
—
—
—
0
0
29
111
2.67
5.52
1.2
1.3
49398.23
151102.54
e6/l
0.76
13
59
138
929
1.57
5.31
1.3
1.2
35.80
15.19
u/ml
0.75
39
317
31
126
2.51
5.25
1.3
1.3
1608.68
1450.98
e6/l
0.09
22
84
239
1809
1.44
5.21
2.8
2.5
—
—
—
0
0
122
804
1.60
5.13
2.4
2.9
9.55
9.52
umol/l
0.00
101
719
60
323
1.92
5.12
1.2
1.3
—
—
—
0
0
13
23
5.72
5.07
2.2
1.2
—
—
—
0
0
131
1875
0.65
5.02
3.2
3.3
—
—
—
0
0
185
1342
1.48
5.01
4.0
2.9
0.89
1.09
e6/l
0.65
95
802
12
21
5.78
4.76
1.1
1.1
1.64
2.27
u/ml
—
5
5
59
324
1.88
4.76
5.7
4.1
—
—
—
0
0
137
1919
0.66
4.69
2.9
3.3
0.62
0.81
ug/l
2.42
96
1359
27
109
2.52
4.66
1.3
1.4
—
—
—
0
0
98
628
1.63
4.62
1.8
2.0
495.77
152.65
ug/g
0.77
75
496
12
22
5.51
4.61
1.1
1.0
0.89
3.47
u/ml
—
5
6
73
433
1.75
4.59
5.0
2.8
8.44
5.35
e9/l
0.50
55
321
460
3945
1.34
4.50
4.9
3.1
66.79
55.59
u/l
0.99
418
3581
24
94
2.60
4.41
1.3
1.3
—
—
—
0
0
607
6643
0.73
4.39
5.1
5.4
2.35
2.56
mmol/l
7.10
533
5944
21
77
2.77
4.37
3.0
3.3
—
—
—
0
0
99
646
1.60
4.34
2.3
2.4
26.87
33.45
u/l
2.21
87
537
94
609
1.61
4.25
3.4
4.1
94.04
94.78
ng/l
0.03
77
527
318
2602
1.34
4.19
3.2
3.6
2.34
2.35
mmol/l
0.85
271
2242
18
62
2.94
4.19
1.7
1.8
12.91
10.83
%
0.71
18
62
592
6464
0.75
3.86
4.6
4.8
4.27
4.42
mmol/l
2.82
520
5829
126
894
1.48
3.79
3.1
4.3
4.35
28.07
ug/l
1.81
114
758
290
2374
1.33
3.72
3.0
2.5
—
—
—
0
0
586
6396
0.76
3.71
4.6
4.8
1.46
1.43
mmol/l
0.59
511
5704
35
176
2.03
3.68
2.2
3.4
538.40
2100.59
u/ml
0.54
30
166
13
35
3.75
3.60
1.6
1.7
9.48
10.40
mmol/l
0.35
13
35
25
111
2.29
3.57
1.4
1.6
—
—
—
0
0
282
2325
1.31
3.39
2.8
2.2
223.82
234.76
u/l
0.04
257
2178
387
3329
1.29
3.37
2.3
2.1
91.38
94.07
pmol/l
0.55
237
1688
7
225
0.31
3.35
1.0
1.4
—
—
—
0
0
13
43
3.05
3.26
1.1
1.0
—
—
—
0
0
9
19
4.77
3.24
2.2
2.0
—
—
—
0
0
8
15
5.37
3.19
13.4
19.7
1679.75
1690.13
nmol/l
—
8
15
8
15
5.37
3.19
9.4
14.9
1171.00
937.07
nmol/l
—
8
15
11
29
3.83
3.19
2.0
1.1
—
—
—
0
0
13
44
2.98
3.14
1.1
1.0
—
—
—
0
0
66
424
1.60
3.14
1.4
1.9
1.86
1.52
g/l
2.24
57
368
54
330
1.68
3.12
1.9
2.7
10.29
10.60
g/l
0.20
47
287
16
62
2.61
3.05
1.3
1.2
—
—
—
0
0
612
6585
0.78
3.02
5.2
5.1
6.04
6.11
mmol/l
0.67
545
5818
7
13
5.42
2.87
1.0
1.2
—
—
—
0
0
247
2040
1.29
2.87
1.6
1.6
19.09
20.54
nmol/l
0.82
212
1703
193
1546
1.32
2.81
3.4
3.2
2.49
2.46
mmol/l
5.51
171
1355
5
6
8.37
2.75
1.0
1.0
—
—
—
0
0
5
6
8.37
2.75
1.0
1.0
—
—
—
0
0
5
6
8.37
2.75
1.0
1.0
—
—
—
0
0
312
2669
1.26
2.70
4.3
3.7
7.00
5.86
ph
—
6
118
282
2388
1.26
2.65
6.4
4.2
—
—
—
0
0
6
11
5.48
2.54
1.5
1.2
—
—
—
0
0
17
76
2.26
2.45
1.2
1.3
265.40
275.17
mosm/kgh2o
—
10
54
27
145
1.89
2.44
2.7
1.9
67.41
59.82
%
0.75
27
145
577
6197
0.81
2.43
4.1
4.3
1.25
1.26
mmol/l
0.18
499
5478
154
1229
1.31
2.29
1.3
1.2
0.93
1.39
u/ml
1.13
35
308
594
6346
0.81
2.29
6.6
6.6
42.13
40.96
mmol/mol
2.13
533
5758
292
3347
0.81
2.27
4.9
5.6
2.52
4.86
ug/l
1.01
245
2926
314
2733
1.23
2.25
2.4
2.4
—
—
—
0
0
89
656
1.40
2.23
5.1
3.8
1.21
1.22
mmol/l
1.33
83
563
74
529
1.43
2.20
1.7
1.5
—
—
—
0
0
16
74
2.18
2.15
1.2
1.1
2.90
7.88
u/ml
—
10
32
37
228
1.65
2.14
3.9
3.3
0.84
0.82
nmol/l
0.11
29
177
29
169
1.74
2.06
3.1
2.8
35.71
32.44
umol/l
0.26
24
149
75
545
1.41
2.05
1.8
1.5
—
—
—
0
0
12
50
2.42
2.03
1.4
2.8
—
—
—
0
0
21
112
1.90
1.97
1.1
1.1
—
—
—
0
0
5
11
4.56
1.94
2.0
5.5
15.12
14.82
ml/dl
—
5
11
6
16
3.77
1.93
1.0
1.6
—
—
—
0
0
42
276
1.55
1.90
1.9
2.6
34.17
37.40
g/l
2.89
36
234
146
1771
0.79
1.86
1.6
1.6
1.41
1.29
mmol/l
0.68
121
1441
8
181
0.44
1.83
1.6
1.4
—
—
—
0
0
485
5232
0.84
1.82
51.0
22.8
326.47
331.71
g/l
25.70
478
5190
7
23
3.06
1.80
1.0
1.0
—
—
—
0
0
376
3387
1.19
1.80
4.7
4.1
0.00
0.00
estimate
0.50
87
617
23
132
1.76
1.75
1.5
2.1
—
—
—
0
0
370
3335
1.19
1.74
6.5
5.4
0.00
0.00
estimate
-0.00
92
637
372
3355
1.19
1.74
4.7
4.1
0.00
0.00
estimate
0.74
94
690
206
1767
1.22
1.66
2.0
1.8
1165.01
1179.99
nmol/l
0.06
154
1321
7
25
2.81
1.65
1.0
1.0
—
—
—
0
0
79
603
1.34
1.64
4.7
4.2
—
—
—
0
0
11
49
2.26
1.64
2.1
3.3
33.60
34.68
%
—
5
32
5
14
3.59
1.61
6.2
5.5
—
—
—
0
0
6
20
3.01
1.58
1.2
1.3
—
—
—
0
0
18
99
1.83
1.58
1.3
1.3
—
—
—
0
0
59
434
1.38
1.55
1.2
1.2
—
—
—
0
0
49
349
1.43
1.55
1.7
1.3
—
—
—
0
0
43
299
1.46
1.54
1.8
3.0
0.43
0.26
g/l
0.63
19
112
21
123
1.72
1.52
1.5
1.4
—
—
—
0
0
698
7247
0.83
1.46
55.6
25.1
130.21
132.79
g/l
4.17
688
7090
698
7246
0.83
1.45
55.2
24.9
4.38
4.39
e12/l
0.05
683
6983
698
7245
0.83
1.44
55.0
24.8
91.83
91.80
fl
0.06
688
7092
698
7245
0.83
1.44
55.0
24.8
30.03
30.49
pg
7.64
688
7091
698
7245
0.83
1.44
55.7
25.1
39.41
39.27
%
0.21
645
6663
698
7244
0.83
1.43
55.1
24.9
268.96
235.51
e9/l
22.40
683
7013
11
213
0.51
1.43
1.3
1.2
—
—
—
0
0
696
6676
1.19
1.39
46.5
16.7
29.38
27.79
mg/l
0.77
662
5404
6
23
2.62
1.37
4.2
3.0
—
—
—
0
0
15
82
1.84
1.36
1.7
2.7
0.41
1.53
g/24h
—
7
40
699
7245
0.84
1.36
55.2
24.9
8.50
6.86
e9/l
44.66
683
6981
16
90
1.79
1.33
1.6
1.1
—
—
—
0
0
18
106
1.71
1.30
1.6
1.4
120.71
112.06
u/ml
—
7
17
5
18
2.79
1.28
3.4
2.6
41521.00
41611.11
ug/l
—
5
18
365
3352
1.15
1.26
3.0
2.7
—
—
—
0
0
5
19
2.64
1.21
1.0
1.1
—
—
—
0
0
5
19
2.64
1.21
1.8
1.2
—
—
—
0
0
16
93
1.73
1.21
1.2
1.3
—
—
—
0
0
12
64
1.89
1.18
1.3
1.3
—
—
—
0
0
7
30
2.34
1.12
1.0
1.0
—
—
—
0
0
55
425
1.31
1.11
2.7
2.5
—
—
—
0
0
10
51
1.97
1.11
1.0
1.2
—
—
—
0
0
13
73
1.79
1.11
1.2
1.3
—
—
—
0
0
14
229
0.61
1.06
10.8
12.1
—
—
—
0
0
14
82
1.72
1.05
1.0
1.2
—
—
—
0
0
14
84
1.68
0.98
1.0
1.0
—
—
—
0
0
15
92
1.64
0.97
1.1
2.2
—
—
—
0
0
40
302
1.34
0.97
3.3
2.9
4.14
4.30
pmol/l
0.49
31
256
31
421
0.73
0.97
6.7
4.0
—
—
—
0
0
196
1755
1.15
0.96
4.4
3.8
—
—
—
0
0
181
1614
1.15
0.94
4.6
3.9
—
—
—
0
0
6
27
2.23
0.93
1.2
2.3
—
—
—
0
0
12
70
1.72
0.93
1.4
1.1
—
—
—
0
0
15
94
1.61
0.91
1.3
1.5
—
—
—
0
0
6
30
2.01
0.87
1.3
1.6
—
—
—
0
0
6
114
0.52
0.83
1.2
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.5
—
1.55
—
0
26
0
27
0.00
0.77
0.0
1.3
—
119.73
—
0
20
134
1506
0.87
0.77
5.4
4.5
1.02
1.02
kg/l
0.52
27
226
13
196
0.66
0.74
1.3
1.2
—
—
—
0
0
8
132
0.60
0.74
1.0
1.3
—
—
—
0
0
686
7035
0.89
0.72
18.0
11.2
24.33
24.96
u/l
0.26
669
6701
76
648
1.19
0.71
1.3
1.4
—
—
—
0
0
5
26
1.93
0.70
1.0
1.3
98.00
151.10
mmol/24h
—
5
26
7
41
1.71
0.70
1.1
1.6
—
—
—
0
0
12
77
1.57
0.68
1.3
1.2
—
—
—
0
0
5
27
1.86
0.68
1.8
1.4
—
—
—
0
0
7
42
1.67
0.68
1.4
1.6
71.43
86.62
umol/l
—
7
42
7
43
1.63
0.67
1.7
1.3
—
—
—
0
0
7
43
1.63
0.67
7.0
2.0
—
—
—
0
0
5
28
1.79
0.66
1.6
1.0
—
—
—
0
0
11
70
1.58
0.65
1.2
1.1
—
—
—
0
0
18
247
0.72
0.65
8.5
4.9
—
—
—
0
0
20
146
1.38
0.64
1.3
1.2
2.06
2.90
u/ml
—
5
15
5
29
1.73
0.64
4.2
5.5
—
—
—
0
0
90
788
1.16
0.63
1.3
1.3
—
—
—
0
0
8
50
1.61
0.61
1.3
1.2
—
—
—
0
0
8
51
1.57
0.60
2.5
2.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
15
105
1.44
0.60
1.1
1.2
373.57
329.72
u/ml
—
7
57
12
80
1.51
0.60
1.2
1.3
—
0.68
—
0
6
13
89
1.47
0.58
1.2
1.2
—
—
—
0
0
20
149
1.35
0.58
1.3
1.2
14.52
2.69
u/ml
—
5
23
6
37
1.63
0.55
1.3
1.2
—
—
—
0
0
483
5002
0.93
0.54
5.8
4.4
—
—
—
0
0
202
1880
1.10
0.53
5.1
4.3
0.00
0.00
estimate
-0.00
83
602
509
4922
1.08
0.53
4.1
3.8
15.14
15.06
pmol/l
0.28
455
4321
697
7105
0.91
0.51
44.8
20.5
4.02
4.01
mmol/l
0.38
685
6890
13
93
1.40
0.48
2.9
2.6
—
—
—
0
0
12
166
0.72
0.48
7.7
3.7
36.17
32.09
mg/l
—
6
111
44
514
0.85
0.46
2.6
2.2
13.77
11.80
nmol/l
0.83
34
442
18
138
1.31
0.45
1.2
1.2
—
—
—
0
0
25
201
1.25
0.45
1.6
1.6
—
—
—
0
0
697
7093
0.92
0.45
44.5
20.3
138.88
139.61
mmol/l
9.55
685
6884
670
6826
0.93
0.43
34.4
16.3
—
—
—
0
0
9
128
0.70
0.43
1.1
1.8
—
—
—
0
0
5
32
1.57
0.42
1.6
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
3.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
1690.29
—
0
17
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
43
495
0.86
0.39
3.6
3.4
—
—
—
0
0
10
71
1.41
0.39
1.3
1.3
—
—
—
0
0
596
6082
0.94
0.37
5.3
4.7
1.87
2.24
mu/l
1.04
544
5378
16
202
0.79
0.37
4.0
2.7
—
—
—
0
0
9
70
1.29
0.36
1.6
1.7
—
—
—
0
0
5
76
0.66
0.36
1.2
1.2
345.40
349.47
nmol/l
—
5
63
6
44
1.37
0.34
1.3
1.3
—
—
—
0
0
6
46
1.31
0.33
1.3
1.3
—
—
—
0
0
6
47
1.28
0.32
1.3
1.3
—
—
—
0
0
6
47
1.28
0.32
1.3
1.3
—
—
—
0
0
54
600
0.89
0.31
1.5
1.5
—
—
—
0
0
10
126
0.79
0.24
1.4
1.7
—
—
—
0
0
550
5587
0.96
0.23
43.3
19.9
15.71
15.45
%
0.51
543
5476
156
1629
0.95
0.22
1.3
1.3
—
—
—
0
0
245
2373
1.04
0.22
3.2
3.3
934.89
355.03
mg/l
0.72
161
1536
28
248
1.13
0.22
1.1
1.1
—
30.17
—
0
6
0
11
0.00
0.21
0.0
1.0
—
18.23
—
0
11
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
18
154
1.17
0.21
1.2
1.6
—
—
—
0
0
15
126
1.19
0.21
4.7
3.2
—
—
—
0
0
5
43
1.16
0.21
1.0
1.0
338.00
280.16
mg/l
—
5
37
44
403
1.10
0.20
3.2
2.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
2.2
1.1
—
—
—
0
0
20
174
1.15
0.19
1.4
1.7
17697.13
16247.55
e6/l
0.07
15
121
15
127
1.18
0.19
1.0
1.1
—
—
—
0
0
7
61
1.15
0.17
2.1
2.1
1.36
2.07
ug/l
—
7
49
7
62
1.13
0.17
1.9
2.0
1.53
3.09
ug/l
—
7
55
26
234
1.11
0.17
1.3
1.2
—
—
—
0
0
11
92
1.20
0.16
1.6
2.2
—
—
—
0
0
41
383
1.07
0.13
1.2
1.3
—
—
—
0
0
37
347
1.07
0.11
1.2
1.4
—
58.64
—
0
26
247
2513
0.98
0.10
3.8
3.8
12.68
7.68
mg/mmol
0.67
154
1613
70
674
1.04
0.09
4.0
3.4
—
—
—
0
0
5
46
1.09
0.09
1.4
1.3
—
—
—
0
0
16
176
0.91
0.09
1.3
1.1
—
—
—
0
0
5
47
1.06
0.09
1.6
1.1
—
—
—
0
0
94
969
0.97
0.09
1.4
1.4
—
—
—
0
0
5
62
0.81
0.08
1.2
1.1
1.29
1.45
nmol/l
—
5
55
6
73
0.82
0.07
1.0
1.1
—
—
—
0
0
19
178
1.07
0.05
1.6
1.3
—
—
—
0
0
35
339
1.03
0.03
1.3
1.3
—
—
—
0
0
242
2402
1.01
0.03
3.2
3.1
6.70
7.20
mmol/l
0.88
199
1951
176
1776
0.99
0.03
1.7
1.8
45000488.26
11002535.83
pmol/l
0.34
140
1427
28
287
0.97
0.01
1.6
2.0
—
—
—
0
0
30
294
1.02
0.00
1.4
1.2
99.32
143.63
iu/ml
—
10
102
12
116
1.03
0.00
3.7
2.6
—
—
—
0
0
15
149
1.01
0.00
1.0
1.1
—
—
—
0
0
21
209
1.00
0.00
2.0
2.3
232.85
79.41
ug/min
0.55
11
121
14
139
1.01
0.00
1.3
1.5
—
—
—
0
0
11
115
0.96
0.00
1.1
1.4
—
—
—
0
0
8
84
0.95
0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.6
—
0.43
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
9
90
1.00
-0.00
1.3
1.8
276.44
296.91
mu/l
—
9
82
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
2.00
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
1.89
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
45
450
1.00
-0.00
4.6
2.8
0.47
0.34
e6/l
0.21
45
439

Mortality – FinRegistry

↥

Association

Association between endpoint COPD_OPPORTUNIST_INFECTIONS and mortality.

Females

Parameter HR [95% CI] p-value
COPD_OPPORTUNIST_INFECTIONS 2.652 [2.3, 3.05] < 0.001
Birth year 1.0 [0.99, 1.01] 0.953

During the follow-up period (1.1.1998 — 31.12.2019), 633 out of 1389 females with COPD_OPPORTUNIST_INFECTIONS died.

Males

Parameter HR [95% CI] p-value
COPD_OPPORTUNIST_INFECTIONS 2.541 [2.21, 2.92] < 0.001
Birth year 0.982 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1245 out of 2143 males with COPD_OPPORTUNIST_INFECTIONS died.

Mortality risk

Mortality risk for people of age

years, who have COPD_OPPORTUNIST_INFECTIONS.

N-year risk Females Males
1 0.272% 0.412%
5 1.622% 2.284%
10 4.163% 5.977%
15 8.101% 11.142%
20 14.53% 18.826%

Relationships between endpoints

↥

Index endpoint: COPD_OPPORTUNIST_INFECTIONS – COPD related to chronic (opportunist) infections

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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