Congenital heart conduction disorder

Q17_CONGENITAL_HEART_CONDUCTION_DISORDER

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Q24.6 Cause of death: ICD-10 — Q24.6 2 out of 7 registries used, show all original rules.	54
4. Check minimum number of events None	54
5. Include endpoints None	54
6. Filter based on genotype QC (FinnGen only)	49

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

NAME	Q17_CONGENITAL_HEART_CONDUCTION_DISORDER
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q246
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q246
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Congenital heart conduction disorder based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	49	38	11
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	24.00	26.77	14.43

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
54: Matched controls
540

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

Q24.6

ICD-10 Finland

Congenital heart block

+∞

77.3

I44.2

ICD-10 Finland

Atrioventricular block, complete

+∞

27.4

Z45.0

ICD-10 Finland

Adjustment and management of cardiac devices

225.2

26.2

Z95.0

ICD-10 Finland

Presence of electronic cardiac devices

150.2

25.3

XFP20

NOMESCO Finland

Check up of cardiac pacemaker

96.7

24.9

FPE30

NOMESCO Finland

Replacement of transvenous cardiac pacemaker pulse generator

+∞

20.0

FM1EE

NOMESCO Finland

Extensive structural and functional ultrasound examination of heart

9.1

15.1

FPE20

NOMESCO Finland

Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes

184.5

14.2

XF400

NOMESCO Finland

ECG with 12 standard connections

9.2

13.3

FM1AE

NOMESCO Finland

Standard cardiac ultrasound examination

8.9

12.9

FPF20

NOMESCO Finland

Implantation of epicardial pacemaker with atrial and ventricular electrodes

+∞

10.8

XF404

NOMESCO Finland

Ambulatory ECG

14.4

10.5

Z2221

NOMESCO Finland

Medical doctor

6.0

9.9

Initial pacemaker installation

+∞

9.7

FN1AC

NOMESCO Finland

Angiography of heart and/or coronary arteries

10.7

9.1

FM2CE, ,

NOMESCO Finland

20.8

9.1

GD1AA

NOMESCO Finland

Thorax X-ray examination

5.6

9.1

112

I47.2

ICD-10 Finland

Ventricular tachycardia

27.0

8.4

ZXD10

NOMESCO Finland

Scheduled procedure

4.9

7.7

124

O99.4

ICD-10 Finland

Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium

92.2

7.6

4260A

ICD-9 Finland

Conduction disorders, Atrioventricular block, complete

+∞

7.5

FM1BE

NOMESCO Finland

Cardiac ultrasound examination through oesophagus

10.7

7.4

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

7.6

6.8

I44.1

ICD-10 Finland

Atrioventricular block, second degree

78.8

6.6

FPH00

NOMESCO Finland

Transvenous extraction of transvenous cardiac pacemaker or cardioverter-defibrillator

78.8

6.6

PH1AC

NOMESCO Finland

Flebography of over extremity with X-ray

+∞

6.4

ZXE30

NOMESCO Finland

More than five and less than seven hours

13.3

6.1

TPH07

NOMESCO Finland

Cathetrisation of artery

7.5

6.0

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3018677) aPTT in Platelet poor plasma by Coagulation assay

7.00

10.34

3.7

4.3

30.01

30.82

0.23

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

5.24

8.43

2.3

—

(3044640) Blood type and Crossmatch panel - Blood

124

4.19

6.35

2.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

196

3.23

4.11

3.0

2.5

—

(3020779) Urea [Moles/volume] in Serum or Plasma

4.56

3.93

8.1

10.6

5.10

6.20

mmol/l

0.74

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.57

3.41

4.8

9.0

24.00

24.43

mmol/l

0.31

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

5.67

3.19

7.0

19.7

—

(3000991) Gas panel - Venous blood

3.11

2.77

6.4

11.0

—

(3023368) Bacteria identified in Blood by Culture

2.91

2.76

2.6

3.4

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

4.86

2.57

1.4

2.1

11.57

3.53

ug/l

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

3.28

2.53

8.5

7.3

107.36

103.77

mmol/l

2.07

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

4.56

2.45

7.4

22.1

23.71

24.17

mmol/l

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

4.30

2.34

7.4

21.0

0.54

0.75

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

4.07

2.23

7.3

20.0

1.96

1.73

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

4.08

1.99

5.2

6.0

167.00

176.75

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

2.88

1.90

1.1

2.3

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.95

1.81

6.9

16.6

0.98

1.07

mmol/l

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

3.82

1.65

6.4

8.3

2.56

3.16

g/l

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

3.08

1.55

5.0

6.9

86.00

93.00

—

(3044889) 12 lead EKG panel

231

1.95

1.54

4.5

2.8

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

3.33

1.47

9.4

21.9

1.05

1.14

mg/l

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.24

1.46

1.9

2.6

0.77

0.62

e6/l

—

(3000494) Fungus identified in Specimen by Culture

2.25

1.34

1.1

1.4

—

(3045414) Leukocytes [Presence] in Urine

2.65

1.18

1.6

1.5

—

(3002256) Pathology report gross observation

2.05

0.87

1.0

1.1

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

1.82

0.85

1.5

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.82

0.85

2.5

1.6

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.84

0.81

2.0

2.5

—

(36304419) Bacteria [Presence] in Urine

110

1.65

0.80

2.5

3.4

—

(3002582) Erythrocytes [#/volume] in Urine

119

1.63

0.80

2.4

3.5

31.68

47.48

e6/l

0.22

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

455

0.59

0.78

12.4

7.9

25.27

23.71

u/l

0.30

438

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.10

0.75

1.2

1.0

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

1.86

0.75

1.6

1.5

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

1.86

0.75

1.6

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

1.86

0.75

1.6

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

1.86

0.75

1.6

1.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

130

1.58

0.74

3.0

3.5

—

(3003694) ABO and Rh group [Type] in Blood

149

1.54

0.72

1.4

1.7

—

(40758558) Short blood count panel - Blood

113

1.59

0.72

5.6

5.4

—

(3022621) pH of Urine by Test strip

1.94

0.70

1.4

2.0

—

(3018095) Leukocytes [#/volume] in Urine

150

1.53

0.70

2.8

4.0

8.08

57.44

e6/l

1.14

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

141

1.54

0.69

2.2

2.3

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.67

0.64

2.1

2.8

2.52

2.59

g/l

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.62

0.0

1.1

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.61

0.0

1.3

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.61

0.0

1.1

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.61

0.0

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

1.70

0.58

1.3

1.4

—

(3005033) Fetal Nuchal fold Thickness US

1.70

0.58

1.3

1.4

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

282

1.44

0.57

6.1

6.0

70.45

84.85

u/l

2.01

264

(3043238) Trisomy 21 risk [Likelihood] in Fetus

1.65

0.56

1.3

1.4

—

(3042936) Bacteria identified in Isolate by Culture

1.60

0.55

3.2

1.7

—

(3019832) Treponema pallidum Ab [Presence] in Serum

122

1.44

0.50

1.4

1.6

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.60

0.47

2.0

1.9

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

446

1.68

0.47

13.4

9.2

19.74

20.04

mg/l

0.03

325

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

1.53

0.46

1.6

572.75

495.80

pmol/l

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.53

0.45

1.6

1.5

—

(3012544) pH of Venous blood

1.42

0.43

6.4

5.1

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.42

0.0

1.1

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.42

0.0

1.1

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.42

0.0

2.8

—

43.00

—

(1761868) Lipid panel - Serum or Plasma

145

0.70

0.42

1.8

2.3

—

(3037467) Urinalysis macro (dipstick) panel - Urine

302

1.34

0.40

6.1

4.2

—

(3013512) EKG study

1.45

0.40

6.0

2.9

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

100

1.40

0.38

3.3

3.1

—

(3050129) First trimester maternal screen panel - Serum or Plasma

1.41

0.36

1.5

1.4

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

357

1.33

0.35

4.8

3.7

2.64

2.75

mmol/l

0.31

338

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

337

1.31

0.34

3.2

1.22

1.13

mmol/l

0.38

319

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

140

1.31

0.33

1.6

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.40

0.33

1.3

1.4

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

103

1.35

0.32

3.2

2.6

188.74

12.31

ng/l

—

(3022096) Basophils/100 leukocytes in Blood

219

1.26

0.30

7.1

6.7

0.66

0.60

0.20

206

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.65

0.28

1.8

1.7

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

167

0.78

0.26

1.9

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.35

0.24

1.2

1.1

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

355

1.24

0.23

3.7

3.5

1.41

1.52

mmol/l

1.15

335

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.24

0.22

1.6

1.4

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.24

0.22

5.4

3.9

5.10

5.15

kpa

—

(3041096) Erythrocytes [Presence] in Urine by Automated

122

0.78

0.22

1.4

3.1

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.21

0.0

1.5

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.0

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.21

0.0

3.5

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.0

—

(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

1.1

—

1.80

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

28.10

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.21

0.0

2.3

—

82.92

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.21

0.0

1.2

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.00

0.21

0.0

1.4

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3020891) Body temperature

0.00

0.21

0.0

3.2

—

(3006504) Eosinophils/100 leukocytes in Blood

226

1.20

0.20

7.4

6.5

2.45

2.84

0.59

216

(3021589) Normoblasts [#/volume] in Blood

217

1.19

0.19

6.6

7.7

0.00

e9/l

-0.00

179

(40760892) CBC W Ordered Manual Differential panel - Blood

223

0.84

0.19

8.7

7.6

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

130

1.21

0.18

1.9

2.2

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

369

1.20

0.18

11.7

7.8

96.50

96.66

ml/min/173m2

0.01

277

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

359

1.20

0.17

3.8

3.4

4.38

4.64

mmol/l

0.90

340

(3019069) Monocytes/100 leukocytes in Blood

229

1.17

0.16

7.8

6.8

8.53

7.97

0.60

219

(3018010) Neutrophils/100 leukocytes in Blood

230

1.16

0.15

7.4

6.2

55.33

54.71

0.10

219

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

115

0.84

0.12

1.3

1.4

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.18

0.10

1.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

406

1.16

0.10

4.5

4.0

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.06

0.08

1.4

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.84

0.07

1.6

1.5

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

179

1.09

0.06

2.2

2.0

—

(3026008) Bacteria identified in Urine by Culture

130

1.10

0.05

4.1

2.6

—

(40768804) Tissue Pathology biopsy report

150

1.09

0.05

1.9

1.7

—

(3002030) Lymphocytes/100 leukocytes in Blood

240

1.08

0.04

7.4

6.3

30.54

31.83

0.31

230

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

117

0.92

0.02

1.8

1.7

97.88

98.58

pmol/l

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

156

0.95

0.00

3.0

3.3

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.1

—

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.0

1.4

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

7.34

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

0.00

—

(3005082) Progesterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

25.10

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

3.91

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.0

1.3

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.5

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

0.0

7.4

—

0.59

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.0

—

3.15

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

-0.00

0.0

1.4

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3018133) Calcium [Moles/volume] in Urine

0.00

-0.00

0.0

3.3

—

1.65

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

1.0

—

0.00

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

8.1

—

1701.43

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

57.00

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.3

—

1.30

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3004809) Band form neutrophils/100 leukocytes in Blood

0.00

-0.00

0.0

2.9

—

4.14

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

1.0

—

11.74

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.8

—

72.67

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

0.30

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

1.0

—

30.00

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3013005) Retinol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

1.62

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

1.0

—

0.00

—

(44813793) Dust mix specific IgE antibody measurement

0.00

-0.00

0.0

1.0

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

7.7

—

905.00

—

(3016616) Dehydroepiandrosterone sulfate (DHEA-S) [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

4.22

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

2.7

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

7.74

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.2

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

-0.00

0.0

1.0

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

1.0

—

40.13

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

10.9

—

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

-0.00

0.0

1.8

—

4.02

—

(3022229) Phosphate [Moles/volume] in Urine

0.00

-0.00

0.0

3.0

—

12.14

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.5

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

1.0

—

0.00

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

23.80

—

(21494755) Public health laboratory ask at order entry panel

0.90

-0.00

1.0

1.2

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

-0.00

0.0

2.8

—

40.43

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.8

—

8.64

—

(3036180) Methadone [Presence] in Urine

0.00

-0.00

0.0

1.8

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.2

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

-0.00

0.0

3.4

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

-0.00

0.0

3.5

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

-0.00

0.0

1.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

2.4

—

19.14

—

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: Q17_CONGENITAL_HEART_CONDUCTION_DISORDER – Congenital heart conduction disorder

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Congenital heart conduction disorder

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Congenital heart conduction disorder (Q17_CONGENITAL_HEART_CONDUCTION_DISORDER)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints