No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
734 |
4. Check minimum number of events
Min. number of events
3
|
734 |
5. Include endpointsNone |
734 |
6. Filter based on genotype QC (FinnGen only) |
706 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF5
Biological medicines for asthma
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1297 | 753 | 538 |
| Only index persons | 1280 | 749 | 531 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 50.20 | 49.28 | 51.58 |
| Only index persons | 50.32 | 49.31 | 51.75 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 706 | 457 | 249 |
| Unadjusted period prevalence (%) | 0.15 | 0.16 | 0.11 |
| Median age at first event (years) | 55.58 | 54.73 | 57.13 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 734
- Matched controls
- 7340
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J32.4
ICD-10 Finland
Chronic pansinusitis
61.3
318.0
181
39
J45.0
ICD-10 Finland
Predominantly allergic asthma
18.4
307.7
379
403
R03BB04
ATC
tiotropium bromide; inhalant
24.3
307.7
341
253
ZX112
NOMESCO Finland
Subcutaneous
52.9
307.7
201
52
D11AH05
ATC
dupilumab; topical
+∞
307.7
326
*
395
Kela drug reimbursment
Dupilumab
4667.1
307.7
302
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
19.1
307.7
521
834
R03DC03
ATC
montelukast; oral
32.0
307.7
587
814
J45.1
ICD-10 Finland
Nonallergic asthma
19.0
305.3
287
240
R03AK08
ATC
formoterol and beclometasone; inhalant
22.7
304.8
252
165
J45.9
ICD-10 Finland
Asthma, unspecified
13.7
294.6
464
819
J33.0
ICD-10 Finland
Polyp of nasal cavity
35.5
293.8
195
74
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
32.6
293.0
201
84
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
18.4
279.2
261
214
H02AB06
ATC
prednisolone; systemic
51.3
245.2
706
2419
J46
ICD-10 Finland
Status asthmaticus
30.0
241.1
168
72
J33.8
ICD-10 Finland
Other polyp of sinus
30.6
216.0
148
60
R03DX05
ATC
omalizumab; parenteral
+∞
215.5
196
*
344
Kela drug reimbursment
Omalizumab
+∞
210.9
192
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
11.6
207.6
265
340
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
28.6
202.6
142
61
J45
ICD-10 Finland
Asthma
10.5
199.5
281
408
UDH02
NOMESCO Finland
Rhinopharyngoscopy
12.0
197.9
240
286
XG474
NOMESCO Finland
Exhalation nntrogen oxide
19.4
195.9
165
108
D11AH01
ATC
tacrolimus; topical
47.3
194.7
116
29
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
48.0
180.6
107
26
DHB20
NOMESCO Finland
Polypectomy of internal nose
45.1
179.4
108
28
XQ800
NOMESCO Finland
Prick test
10.2
175.5
243
341
R03DA04
ATC
theophylline; systemic, rectal
18.2
174.9
151
103
R03BA08
ATC
ciclesonide; inhalant
9.7
173.0
252
376
R03DX09
ATC
mepolizumab; parenteral
+∞
170.7
157
*
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
13.3
168.1
178
172
TDM10
NOMESCO Finland
Puncture of maxillary antrum
14.3
164.6
165
146
3028
Kela drug reimbursment
Mepolizumab
1937.6
162.8
152
*
R06AX27
ATC
desloratadine; oral
7.7
160.0
510
1681
297, ,
Kela drug reimbursment
+∞
159.3
147
*
J45.8
ICD-10 Finland
Mixed asthma
18.5
156.0
132
86
R03AK11
ATC
formoterol and fluticasone; inhalant
22.4
155.0
119
63
R03AK06
ATC
salmeterol and fluticasone; inhalant
7.8
153.6
288
564
L50.1
ICD-10 Finland
Idiopathic urticaria
57.9
153.4
87
17
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
17.1
148.7
131
92
R01AD08
ATC
fluticasone; nasal
6.5
139.5
466
1553
C01CA24
ATC
epinephrine; parenteral
8.9
138.6
205
306
R96
ICPC
Asthma
8.5
136.6
211
331
L50.8
ICD-10 Finland
Other urticaria
22.3
136.3
104
54
R03BA02
ATC
budesonide; inhalant
6.4
134.2
331
835
R03AC13
ATC
formoterol; inhalant
12.4
132.0
143
141
R06AE09
ATC
levocetirizine; oral
6.5
131.1
304
722
L20.0
ICD-10 Finland
Besnier prurigo
7.7
126.2
217
381
D11AH02
ATC
pimecrolimus; topical
45.6
124.0
74
18
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
18.3
123.0
103
65
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
12.2
121.4
131
128
H02AB04
ATC
methylprednisolone; systemic
6.4
117.7
255
562
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
12.1
116.0
126
124
D11AX14
ATC
[U] tacrolimus
59.3
115.4
65
12
L50.9
ICD-10 Finland
Urticaria, unspecified
10.9
114.7
135
149
R03DX10
ATC
benralizumab; systemic
+∞
114.7
107
*
R03AK07
ATC
formoterol and budesonide; inhalant
5.5
114.2
352
1057
L04AD01
ATC
ciclosporin; systemic
18.9
113.4
93
56
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
28.0
113.1
78
31
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
25.2
112.7
81
36
3027
Kela drug reimbursment
Benralizumab
+∞
111.3
104
*
R03AC02
ATC
salbutamol; inhalant
8.8
108.0
644
3288
251, ,
Kela drug reimbursment
+∞
106.9
100
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
12.6
106.7
111
102
UDM02
NOMESCO Finland
Sinoscopy
15.2
105.1
97
73
R03AC12
ATC
salmeterol; inhalant
12.2
104.0
111
106
DPA30
NOMESCO Finland
Sphenotomy
33.4
103.3
67
22
H02AB07
ATC
prednisone; oral
6.0
101.6
229
517
R03BA05
ATC
fluticasone; inhalant
5.2
99.4
297
854
J33.9
ICD-10 Finland
Nasal polyp, unspecified
26.2
95.1
67
28
R06AE07
ATC
cetirizine; oral
5.2
93.2
539
2546
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
9.0
92.8
126
166
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
34.9
90.7
58
18
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
9.0
87.0
117
152
H02AB09
ATC
hydrocortisone; systemic
14.8
86.6
80
60
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.6
84.6
194
439
R01AD58
ATC
fluticasone, combinations; nasal
4.3
83.4
373
1426
XG410
NOMESCO Finland
Flow-volume spirometry
10.3
81.7
97
107
R06AX22
ATC
ebastine; oral
4.5
81.1
278
872
D07AB08
ATC
desonide; topical
5.3
77.4
188
445
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
12.7
75.2
76
66
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
6.3
74.9
144
275
WZC30
NOMESCO Finland
Teaching
4.6
73.1
220
619
D02AE01
ATC
carbamide; topical
6.9
71.5
122
206
TQW80
NOMESCO Finland
Local dermatologic skincare
12.0
71.4
75
69
R03BA01
ATC
beclometasone; inhalant
4.7
71.1
207
566
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
6.6
68.3
121
212
49300
ICD-8 Finland
Asthma, bronchiale
12.4
68.2
70
62
D02AX
ATC
Other emollients and protectives
10.1
66.3
79
87
XQ802
NOMESCO Finland
Epicutan test
7.2
66.2
106
167
R01AD12
ATC
fluticasone furoate; nasal
3.7
65.8
409
1878
R03AC03
ATC
terbutaline; inhalant
4.3
63.1
207
615
Z51.6
ICD-10 Finland
Desensitization to allergens
17.2
63.0
53
33
D07BA04
ATC
hydrocortisone and antiseptics; topical
4.9
62.5
161
396
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.5
62.2
427
2067
E0000UV, ,
ATC
3.5
61.3
446
2231
R01AD05
ATC
budesonide; nasal
5.3
61.2
140
311
D07AA02
ATC
hydrocortisone; topical
4.1
60.6
218
691
E000003, ,
ATC
7.0
60.1
98
157
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
20.8
58.5
45
23
R01AD09
ATC
mometasone; nasal
3.6
58.0
501
2753
D07AC01
ATC
betamethasone; topical
3.4
57.9
384
1798
R06AX13
ATC
loratadine; oral
3.8
57.4
232
794
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
4.1
56.0
187
559
J01MA14
ATC
moxifloxacin; systemic
5.1
55.1
132
304
Z88.6
ICD-10 Finland
Personal history of allergy to analgesic agent
201.7
54.8
56
*
L04AX03
ATC
methotrexate; systemic
4.6
54.0
151
394
R03DC01
ATC
zafirlukast; oral
13.6
53.4
51
40
R06AX26
ATC
fexofenadine; oral
4.9
53.3
135
325
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
9.8
53.2
64
71
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.6
52.4
232
837
L50.3
ICD-10 Finland
Dermatographic urticaria
10.6
51.3
58
59
J01.0
ICD-10 Finland
Acute maxillary sinusitis
3.2
51.1
317
1403
D09AB01
ATC
zinc bandage without supplements; topical
13.8
50.7
48
37
ZXA10
NOMESCO Finland
Bilateral
3.7
50.6
200
668
R02
ICPC
Shortness of breath/dyspnoea
4.1
49.6
160
463
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
20.0
48.7
38
20
D07AB02
ATC
hydrocortisone butyrate; topical
3.1
48.2
317
1441
ZXC95
NOMESCO Finland
Use of surgical navigator
13.6
48.1
46
36
J01FA06
ATC
roxithromycin; oral
3.0
46.7
395
2054
E000001, ,
ATC
3.3
46.5
239
937
L50
ICD-10 Finland
Urticaria
10.0
45.9
54
58
N05BB01
ATC
hydroxyzine; systemic
5.2
45.9
104
227
J30.3
ICD-10 Finland
Other allergic rhinitis
6.2
45.5
83
148
E000002, ,
ATC
3.9
45.3
159
487
S01GX01
ATC
cromoglicic acid; ophthalmic
3.2
45.2
260
1087
J47
ICD-10 Finland
Bronchiectasis
12.6
43.1
43
36
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.4
42.4
91
189
D07AC13
ATC
mometasone; topical
2.9
42.2
300
1403
J33
ICD-10 Finland
Nasal polyp
16.7
41.1
35
22
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
3.4
39.2
169
589
J01AA02
ATC
doxycycline; systemic
4.2
39.1
645
4663
L27.2
ICD-10 Finland
Dermatitis due to ingested food
14.0
38.5
36
27
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.1
37.9
209
842
J01FA10
ATC
azithromycin; systemic
3.1
37.8
557
3724
R01AD01
ATC
beclometasone; nasal
3.1
37.3
193
749
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.8
37.2
131
399
XQ848
NOMESCO Finland
Dermatological photography
7.2
36.5
56
83
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.8
36.1
271
1284
T78.4
ICD-10 Finland
Allergy, unspecified
5.1
35.7
80
172
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.1
35.5
108
296
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
5.1
35.4
80
173
J01FA09
ATC
clarithromycin; systemic
2.6
34.9
325
1708
J31.0
ICD-10 Finland
Chronic rhinitis
3.7
34.7
126
391
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.7
34.0
493
3186
R06.0
ICD-10 Finland
Dyspnoea
2.8
33.9
242
1111
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
9.8
33.8
40
43
DHB50
NOMESCO Finland
Turbinoplasty
6.3
33.1
58
99
H65.3
ICD-10 Finland
Chronic mucoid otitis media
7.3
33.0
50
73
R01AD11
ATC
triamcinolone; nasal
3.7
32.8
118
363
D07AD01
ATC
clobetasol; topical
3.0
32.6
178
707
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
45.6
32.1
39
9
134
Kela drug reimbursment
General erythroderma
49.9
31.8
38
8
D72.1
ICD-10 Finland
Eosinophilia
38.4
31.8
40
11
J01FA15
ATC
telithromycin; oral
3.4
30.9
129
436
L20
ICD-10 Finland
Atopic dermatitis
5.5
29.8
60
117
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
11.1
29.7
32
30
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
10.4
29.3
33
33
L50.0
ICD-10 Finland
Allergic urticaria
6.2
28.6
50
85
D11AX15
ATC
[U] pimecrolimus
57.5
28.4
33
6
3DX05, ,
NOMESCO Finland
+∞
28.3
27
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.9
28.1
65
143
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.4
28.1
332
1899
R01BA52
ATC
pseudoephedrine, combinations; oral
2.4
27.6
287
1550
L04AX01
ATC
azathioprine; systemic
4.9
26.6
61
133
TGC00
NOMESCO Finland
Bronchial lavation
7.2
26.5
40
58
E000006, ,
ATC
3.9
26.4
85
241
E000007, ,
ATC
4.0
26.1
80
219
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
10.0
26.0
30
31
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
10.7
25.5
28
27
T78.3
ICD-10 Finland
Angioneurotic oedema
9.4
24.9
30
33
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
24.9
208
1011
DJD20
NOMESCO Finland
Plastic repair of septum of nose
4.7
24.3
58
131
S87
ICPC
Dermatitis/atopic eczema
5.8
23.5
44
80
A02BC02
ATC
pantoprazole; systemic
2.3
23.1
522
3789
J01FF01
ATC
clindamycin; systemic
2.3
23.1
243
1301
J34.2
ICD-10 Finland
Deviated nasal septum
3.7
22.8
77
225
DPW99
NOMESCO Finland
Other operation on frontal or sphenoidal sinus
86.2
22.8
25
*
J01DB01
ATC
cefalexin; oral
3.3
22.7
659
5347
R03BB01
ATC
ipratropium bromide; inhalant
6.3
22.7
39
65
A02BC05
ATC
esomeprazole; systemic
2.2
22.7
339
2086
J01DC02
ATC
cefuroxime; systemic
3.8
22.6
74
212
R03BC03
ATC
nedocromil; inhalant
3.5
21.6
81
254
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.7
21.5
72
209
WQ000
NOMESCO Finland
Hyposensibilisation
17.5
20.6
32
19
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.2
20.5
249
1402
D07BC01
ATC
betamethasone and antiseptics; topical
2.8
20.4
116
463
J01MA12
ATC
levofloxacin; systemic
2.5
20.2
149
676
R06AX18
ATC
acrivastine; oral
5.2
20.2
42
84
GD1AD
NOMESCO Finland
Thorax CT examination
3.9
20.2
61
165
XG405
NOMESCO Finland
Education on PEF monitoring
8.2
20.1
27
34
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
4.4
20.1
52
125
D07AC14
ATC
methylprednisolone aceponate; topical
3.9
20.0
61
166
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.3
19.6
186
943
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
15.2
19.5
32
22
J02AC01
ATC
fluconazole; systemic
2.0
19.5
350
2270
R06.2
ICD-10 Finland
Wheezing
4.1
19.2
55
143
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
20.7
19.2
28
14
J33.1
ICD-10 Finland
Polypoid sinus degeneration
71.8
18.8
21
*
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
7.5
18.8
27
37
L26
ICD-10 Finland
Exfoliative dermatitis
102.7
18.6
20
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.3
18.6
76
251
S01GX08
ATC
ketotifen; ophthalmic
3.6
18.5
64
190
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.9
18.4
41
87
D07CC01
ATC
betamethasone and antibiotics; topical
2.5
18.2
128
567
A07AA02
ATC
nystatin; oral
3.9
17.8
55
151
S01AD03
ATC
aciclovir; ophthalmic
4.7
17.7
42
94
J01DA01
ATC
[U] cefalexin
2.0
17.7
485
3600
WW200
NOMESCO Finland
Immunization
5.0
17.5
38
79
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
24.8
17.4
24
10
H65.2
ICD-10 Finland
Chronic serous otitis media
7.7
17.0
24
32
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
17.0
352
2365
G47.3
ICD-10 Finland
Sleep apnoea
2.1
16.7
197
1082
J32.8
ICD-10 Finland
Other chronic sinusitis
23.7
16.5
23
10
R05
ICD-10 Finland
Cough
2.2
16.4
181
968
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.8
16.3
37
80
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.0
16.1
75
267
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
5.3
15.6
32
63
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.1
15.6
186
1023
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.0
15.6
220
1287
L04AA01
ATC
[U] ciclosporin
12.7
15.5
27
22
R01AD59
ATC
mometasone, combinations; nasal
3.3
15.5
61
197
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
7.2
15.3
23
33
L28.1
ICD-10 Finland
Prurigo nodularis
13.4
15.3
26
20
D07AB01
ATC
clobetasone; topical
4.2
14.9
40
99
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
14.8
445
3313
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
14.8
109
490
N02AX02
ATC
tramadol; systemic, rectal
1.9
14.7
318
2136
UDC00
NOMESCO Finland
Ear microscopy
3.0
14.7
70
253
R03BB07
ATC
umeclidinium bromide; inhalant
15.8
14.5
23
15
D07XC01
ATC
betamethasone; topical
2.5
14.5
104
463
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.9
14.1
31
65
4222
FHL
Endonasal etmoidectomy
18.0
13.9
21
12
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
54.4
13.9
16
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
13.7
206
1224
R03AK03
ATC
[U] fenoterol and ipratropium bromide
4.2
13.7
37
92
A02BC01
ATC
omeprazole; systemic
2.0
13.6
197
1155
M05BA04
ATC
alendronic acid; oral
3.3
13.6
54
175
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
5.4
13.5
27
52
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
13.1
343
2417
A02BA02
ATC
ranitidine; systemic
2.1
13.0
133
687
J01CA04
ATC
amoxicillin; systemic
2.2
12.9
635
5434
N02BE01
ATC
paracetamol; systemic, rectal
2.5
12.8
659
5733
R05
ICPC
Cough
1.9
12.7
198
1187
49302
ICD-8 Finland
Asthma, Rhinitis allergica cum asthmate bronchiali
15.8
12.7
20
13
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.0
12.7
36
93
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
12.6
260
1703
J04BA02
ATC
dapsone; oral
17.7
12.6
19
11
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
17.7
12.6
19
11
J01DA08
ATC
[U] cefaclor
2.2
12.4
113
556
J30.0
ICD-10 Finland
Vasomotor rhinitis
4.3
12.1
31
74
TQX05
NOMESCO Finland
Skin puncture, unspecified location
27.2
12.1
16
6
4711A
ICD-9 Finland
Nasal polyps, Polypoid sinus degeneration
21.7
12.0
17
8
J20
ICD-10 Finland
Acute bronchitis
2.3
12.0
94
433
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
5.1
12.0
25
50
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.8
12.0
61
228
J05AB01
ATC
aciclovir; systemic
1.9
12.0
178
1048
A92
ICPC
Allergy/allergic reaction NOS
3.6
11.8
39
112
SPAT1254
SPAT
Administration of medicine
2.2
11.6
104
508
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
11.3
11.6
21
19
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
9.5
11.6
23
25
S02
ICPC
Pruritus
3.6
11.5
39
114
ZX114
NOMESCO Finland
Intramuscular
5.1
11.5
24
48
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
13.9
11.5
19
14
4AC06, ,
NOMESCO Finland
+∞
11.5
11
*
J05AB11
ATC
valaciclovir; oral
2.1
11.5
122
637
J02AC02
ATC
itraconazole; systemic
2.0
11.4
144
800
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
4.2
11.4
30
73
J01.1
ICD-10 Finland
Acute frontal sinusitis
4.3
11.4
29
69
J01DA09
ATC
[U] cefadroxil
1.8
11.3
212
1340
DHB40
NOMESCO Finland
Conchotomy
35.6
11.3
14
*
S01
ICPC
Pain/tenderness of skin
3.3
11.3
42
131
J01MA02
ATC
ciprofloxacin; systemic
1.8
11.2
257
1725
DHA10
NOMESCO Finland
Biopsy of cavity of nose
9.4
11.1
22
24
J30.4
ICD-10 Finland
Allergic rhinitis, unspecified
3.2
10.9
44
144
L20.8
ICD-10 Finland
Other atopic dermatitis
5.2
10.8
22
43
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
28.5
10.8
14
5
R78
ICPC
Acute bronchitis/bronchiolitis
4.3
10.6
27
64
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.4
10.6
80
363
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
4.7
10.5
24
52
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
14.5
10.5
17
12
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
10.5
60
239
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
10.4
281
1965
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
5.0
10.3
22
45
Z3231
NOMESCO Finland
Registered nurse
1.8
10.3
198
1257
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
10.2
191
1202
E000004, ,
ATC
4.4
10.1
25
58
D07XB05
ATC
dexamethasone; topical
3.8
10.1
31
85
XQ820
NOMESCO Finland
Exposure to medicinal substance
14.8
10.0
16
11
DFF00
NOMESCO Finland
Pure tone audiometry
2.4
9.8
72
322
S88
ICPC
Dermatitis contact/allergic
4.2
9.8
26
64
R60.9
ICD-10 Finland
Oedema, unspecified
3.1
9.6
41
139
S98
ICPC
Urticaria
11.6
9.6
17
15
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.7
9.6
268
1881
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
3.6
9.4
31
89
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.2
9.4
81
388
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
2.8
9.4
47
174
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
3.5
9.4
32
94
S01GX02
ATC
levocabastine; ophthalmic
2.5
9.4
60
252
WXQ26
NOMESCO Finland
UVB broad spectrum light therapy
+∞
9.4
9
*
3006
Kela drug reimbursment
Baricitinib
22.0
9.4
13
6
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
9.3
150
900
A01AB09
ATC
miconazole; local oral
2.4
9.2
65
286
A02BC03
ATC
lansoprazole; oral
1.7
9.2
199
1301
X58
ICD-10 Finland
Exposure to other specified factors
1.9
9.1
124
704
DMB10
NOMESCO Finland
Radical maxillary antrotomy
15.8
9.1
14
9
XG488
NOMESCO Finland
Other provokation of respiratroy tract
37.2
9.0
11
*
GX2C5
NOMESCO Finland
Short-lasting oximetry
18.9
9.0
13
7
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
8.8
206
1375
SPAT1058
SPAT
PEF monitoring instruction
2.4
8.8
59
254
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.1
8.7
35
115
3029
Kela drug reimbursment
Upadacitinib
16.5
8.6
13
8
ZX110
NOMESCO Finland
Intracutaneous
27.9
8.5
11
*
R03AK
ATC
Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics
20.3
8.5
12
6
H66
ICD-10 Finland
Suppurative and unspecified otitis media
3.6
8.4
28
81
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
4.5
8.4
20
45
R49.08
ICD-10 Finland
Other specified dysphonia
3.8
8.4
25
67
I45.9
ICD-10 Finland
Conduction disorder, unspecified
12.9
8.4
14
11
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.7
8.2
184
1209
B07.9
ICD-10 Finland
Verruca simplex
3.0
8.2
36
124
R03BC01
ATC
cromoglicic acid; inhalant
4.1
8.1
22
55
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
8.1
91
483
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
6.9
8.1
19
28
H66.9
ICD-10 Finland
Otitis media, unspecified
2.3
8.0
64
298
S01GX04
ATC
nedocromil; ophthalmic
4.0
7.9
22
56
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
7.9
138
845
L30.3
ICD-10 Finland
Infective dermatitis
3.0
7.8
35
122
R01AD
ATC
Corticosteroids
7.1
7.8
18
26
J01.4
ICD-10 Finland
Acute pansinusitis
7.1
7.8
18
26
D07CB01
ATC
triamcinolone and antibiotics; topical
4.3
7.8
20
48
ZXE00
NOMESCO Finland
One hour or less
1.6
7.7
271
1987
M81.4
ICD-10 Finland
Drug-induced osteoporosis
15.2
7.7
12
8
S01BA01
ATC
dexamethasone; ophthalmic
3.1
7.7
31
102
R06AX12
ATC
terfenadine; oral
2.6
7.6
43
170
V01AA02
ATC
grass pollen; parenteral
18.6
7.6
11
6
L04AF03
ATC
upadacitinib; oral
25.3
7.6
10
*
R60.0
ICD-10 Finland
Localized oedema
2.1
7.6
74
373
A46
ICD-10 Finland
Erysipelas
2.0
7.6
88
473
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.7
7.5
23
63
L03.9
ICD-10 Finland
Cellulitis, unspecified
4.0
7.5
21
54
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.8
7.3
35
127
L50.5
ICD-10 Finland
Cholinergic urticaria
+∞
7.3
7
*
SPAT1260
SPAT
Consultation of another employee
1.8
7.3
118
707
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
15.9
7.2
11
7
L50.2
ICD-10 Finland
Urticaria due to cold and heat
15.9
7.2
11
7
R75
ICPC
Sinusitis acute/chronic
2.4
7.2
49
212
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
7.2
140
884
T78.0
ICD-10 Finland
Anaphylactic shock due to adverse food reaction
20.2
7.1
10
5
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.8
7.1
113
672
B00.10
ICD-10 Finland
Herpes simplex facialis
6.1
7.1
18
30
R06AE08, ,
ATC
6.1
7.1
18
30
Z71.8
ICD-10 Finland
Other specified counselling
1.6
7.1
234
1685
B37.0
ICD-10 Finland
Candidal stomatitis
7.1
7.0
16
23
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.5
7.0
42
172
R29
ICPC
Respiratory symptom/complaint other
2.2
7.0
57
268
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
6.9
534
4610
R81
ICPC
Pneumonia
3.0
6.9
30
103
R09
ICPC
Sinus symptom/complaint
2.0
6.9
75
393
L04AA44
ATC
[U] upadacitinib
13.9
6.9
11
8
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.6
6.9
40
161
WX402
NOMESCO Finland
General anaesthesia
1.7
6.9
152
992
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.9
6.9
82
445
SPAT1255
SPAT
Intravenous administration of medicine
2.4
6.9
45
192
4226
FHL
Posterior radical surgery and possible etmoidectomy
9.4
6.8
13
14
Z01.7
ICD-10 Finland
Laboratory examination
1.8
6.8
110
658
DNB10
NOMESCO Finland
Endonasal ethmoidectomy
40.4
6.8
8
*
J37.0
ICD-10 Finland
Chronic laryngitis
2.9
6.8
31
110
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.6
6.7
39
157
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.3
6.7
50
226
J01DA06
ATC
[U] cefuroxime
1.8
6.7
114
692
L95.8
ICD-10 Finland
Other vasculitis limited to skin
22.7
6.7
9
*
R01AC07
ATC
nedocromil; nasal
22.7
6.7
9
*
X57
ICD-10 Finland
Unspecified privation
3.8
6.7
20
54
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
6.7
307
2371
WX722
NOMESCO Finland
PEEP
2.7
6.7
34
128
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
5.6
6.6
18
33
H26.3
ICD-10 Finland
Drug-induced cataract
7.9
6.6
14
18
N03AX12
ATC
[U] gabapentin; oral
1.7
6.6
117
718
M03BX02
ATC
tizanidine; oral
1.5
6.6
465
3916
B00.0
ICD-10 Finland
Eczema herpeticum
10.1
6.5
12
12
R01AC01
ATC
cromoglicic acid; nasal
2.5
6.5
39
160
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
6.4
69
360
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.3
6.4
48
217
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
70.4
6.4
7
*
4732A
ICD-9 Finland
Chronic sinusitis, Ethmoidal
70.4
6.4
7
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
6.4
109
661
H25.8
ICD-10 Finland
Other senile cataract
2.5
6.4
41
173
R05CB01
ATC
acetylcysteine; inhalant, oral
8.2
6.3
13
16
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
9.4
6.3
12
13
SPAT1263
SPAT
Sampling
1.5
6.3
283
2168
R05FA02
ATC
opium derivatives and expectorants; systemic
1.5
6.3
266
2012
UJF32
NOMESCO Finland
Coloscopy
1.6
6.3
150
997
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.9
6.3
74
400
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
6.3
80
444
3DX08, ,
NOMESCO Finland
+∞
6.3
6
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
6.2
86
489
C09CA06
ATC
candesartan; oral
1.6
6.2
156
1049
R74
ICPC
Upper respiratory infection acute
1.5
6.2
272
2071
S18
ICPC
Laceration/cut
1.5
6.2
293
2266
R49.8
ICD-10 Finland
Other and unspecified voice disturbances
6.4
6.2
15
24
R51.80
ICD-10 Finland
Headache
1.7
6.1
128
822
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.6
6.1
179
1249
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.3
6.1
43
190
4931A
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA SINE EXACERBATIONE]
8.7
6.1
12
14
ZY010
NOMESCO Finland
Hospital outpatient
2.2
6.1
50
236
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.1
6.0
57
284
H10
ICD-10 Finland
Conjunctivitis
2.0
6.0
62
319
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.1
6.0
53
257
4224
FHL
Endonasal anthrostomy
5.6
6.0
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
202
46
60.21
307.65
1.6
1.2
1.60
0.60
u/ml
0.93
146
23
593
442
65.64
307.65
2.7
1.3
872.11
211.33
u/ml
6.79
586
404
180
136
17.21
198.29
1.3
1.1
3.16
2.78
u/ml
0.09
126
69
166
123
17.15
184.34
1.3
1.1
2.99
7.30
u/ml
1.41
119
61
718
3151
59.66
176.01
10.5
6.2
0.33
0.18
e9/l
28.90
690
2797
711
3139
41.37
171.08
9.9
5.8
2.10
1.97
e9/l
0.58
679
2813
156
120
16.24
169.17
1.3
1.0
3.81
1.88
u/ml
0.85
117
58
182
191
12.34
162.41
1.7
1.6
95.56
238.00
titre
—
9
10
147
117
15.46
155.92
1.3
1.1
1.24
0.77
u/ml
0.33
98
46
711
3503
33.86
141.31
10.4
9.0
4.26
3.99
e9/l
3.47
677
3078
126
108
13.88
127.10
1.3
1.0
8.88
4.09
u/ml
1.41
99
53
117
95
14.46
121.79
1.3
1.1
6.37
5.35
u/ml
0.18
86
34
100
89
12.85
97.88
1.2
1.0
0.81
0.37
u/ml
0.45
65
27
232
558
5.62
95.42
3.1
2.1
265.54
369.67
nmol/l
14.18
226
523
115
196
6.77
66.67
1.6
1.5
0.24
0.24
g/l
0.07
110
187
180
467
4.78
65.63
2.7
2.5
9.96
10.51
g/l
1.13
171
429
659
4397
5.88
56.28
5.7
3.8
9.38
10.01
mm/h
0.97
643
4110
140
367
4.48
49.52
1.6
1.6
1.06
1.40
g/l
1.95
130
342
72
145
5.40
34.55
3.2
2.9
—
—
—
0
0
63
114
5.95
33.88
3.7
4.0
56.95
55.58
%
0.30
63
114
61
110
5.96
32.91
3.6
3.5
4.81
4.32
e9/l
0.68
61
110
609
4478
3.11
30.95
7.3
7.2
72.53
76.85
u/l
1.41
593
4222
39
46
8.90
30.75
1.3
1.0
7.91
0.86
u/ml
0.70
24
12
33
33
10.42
29.35
1.1
1.0
5.45
18.07
u/ml
1.49
24
24
38
51
7.80
26.96
4.4
3.4
—
—
—
0
0
255
1329
2.41
26.33
1.7
1.4
2.24
2.33
g/l
0.48
198
852
75
197
4.13
25.90
1.7
1.6
0.06
0.01
iu/ml
—
6
28
29
34
8.84
22.90
1.4
2.4
—
—
—
0
0
170
788
2.51
22.23
2.2
1.9
—
—
—
0
0
718
6192
8.32
22.14
17.9
11.6
14.88
21.37
mg/l
7.83
649
4768
28
13
22.33
19.62
7.8
5.7
—
—
—
0
0
78
255
3.30
19.42
1.2
1.2
0.22
1.79
u/ml
—
5
17
34
59
5.99
18.99
1.1
1.1
—
—
—
0
0
71
230
3.31
17.92
1.9
1.7
—
—
—
0
0
361
2416
1.97
17.88
2.6
2.2
76.50
74.86
nmol/l
0.52
343
2197
164
851
2.19
16.05
2.4
3.5
0.82
0.82
mmol/l
0.01
155
810
234
1395
1.99
15.76
1.9
1.7
0.72
0.99
mg/l
1.24
180
1036
35
76
4.79
15.31
1.2
1.1
—
—
—
0
0
301
1971
1.89
15.22
3.5
2.9
19.93
33.03
ng/l
1.54
182
1153
27
24
11.63
14.87
1.4
1.5
8.28
8.61
ug/l
0.14
27
24
329
2237
1.85
14.61
7.5
8.7
1.11
1.13
inr
0.24
132
698
46
130
3.71
14.28
1.1
1.2
—
9.60
—
0
9
36
85
4.40
14.23
2.6
2.3
18.54
17.25
%
1.04
19
44
78
304
2.75
14.21
2.8
3.4
1.38
1.63
mmol/l
0.29
64
224
25
43
5.98
14.07
1.2
2.2
507.89
553.06
e6/l
0.16
18
35
117
558
2.30
13.91
2.0
1.9
—
—
—
0
0
110
524
2.29
13.08
1.4
1.2
101.00
155.77
iu/ml
1.20
38
224
399
2944
1.78
12.98
4.6
6.3
9.80
10.78
umol/l
1.22
384
2783
113
549
2.25
12.81
2.0
1.9
—
—
—
0
0
23
40
5.90
12.80
1.3
2.3
0.22
0.20
e9/l
0.12
18
34
109
524
2.27
12.67
3.0
2.9
—
—
—
0
0
357
2567
1.76
12.55
5.1
6.7
1.22
1.22
mmol/l
0.13
290
2198
55
190
3.05
12.45
1.2
1.3
—
—
—
0
0
53
180
3.10
12.36
1.1
1.2
—
2.83
—
0
19
186
1108
1.91
12.10
1.3
1.3
10.77
10.32
u/ml
0.03
71
467
734
7047
+∞
12.05
27.0
17.0
41.76
40.79
%
6.27
718
6694
230
1469
1.82
11.99
2.6
2.4
1567.45
5278.86
umol/l
1.54
212
1318
325
2307
1.73
11.71
5.2
6.0
1.21
1.22
mmol/l
0.88
308
2131
313
2201
1.74
11.65
3.6
4.8
36.54
36.56
g/l
0.03
296
2069
425
3256
1.73
11.54
4.6
4.6
6.48
6.51
mmol/l
0.14
405
3013
277
1886
1.75
11.53
3.2
3.0
—
—
—
0
0
194
1188
1.86
11.51
3.1
2.8
353.98
675.65
ng/l
4.03
165
969
734
7061
+∞
11.51
27.5
17.0
139.37
137.26
g/l
4.76
734
6976
665
5868
2.42
11.45
14.2
10.1
89.58
88.91
ml/min/173m2
0.40
591
4803
50
173
3.03
11.30
2.7
2.2
8.76
10.93
mg/l
2.10
50
159
187
1138
1.86
11.29
1.4
1.3
22.86
28.66
iu/ml
0.44
50
379
574
4810
1.89
11.29
4.6
3.9
14.75
14.49
pmol/l
2.03
544
4470
692
6231
2.93
11.22
15.9
12.4
3.88
3.94
mmol/l
7.41
685
6066
58
220
2.78
11.11
1.7
2.0
—
—
—
0
0
79
349
2.42
11.10
1.9
2.7
67.88
67.81
g/l
0.03
74
325
389
2943
1.68
10.77
3.5
3.1
0.00
0.00
estimate
0.50
116
598
37
111
3.46
10.53
1.1
1.1
—
—
—
0
0
33
92
3.71
10.47
1.5
1.6
—
—
—
0
0
687
6215
2.65
10.06
15.8
12.3
139.84
139.67
mmol/l
1.46
679
6061
83
393
2.25
9.94
2.9
3.4
1.23
1.23
mmol/l
0.07
76
352
50
186
2.81
9.94
1.1
1.1
—
—
—
0
0
385
2944
1.65
9.92
4.7
4.3
0.00
0.00
estimate
0.50
118
578
28
73
3.95
9.75
1.3
1.6
—
—
—
0
0
230
1544
1.71
9.75
3.6
3.3
0.00
0.01
estimate
1.08
116
568
387
2972
1.64
9.73
3.6
3.1
0.03
0.01
estimate
0.23
116
543
30
84
3.68
9.47
1.5
1.6
—
—
—
0
0
33
99
3.44
9.41
1.5
1.7
—
—
—
0
0
642
5689
2.03
9.26
5.3
4.6
1.76
2.01
mu/l
0.63
617
5335
226
1530
1.69
9.19
1.4
1.3
1.38
1.77
u/ml
0.19
68
435
232
1582
1.68
9.18
3.1
2.9
37.16
48.71
e6/l
0.19
186
1199
99
519
2.05
9.14
3.1
4.5
246.06
242.05
u/l
0.07
93
492
257
1804
1.65
9.08
2.4
2.6
52.76
59.75
u/l
1.49
238
1673
558
4749
1.73
9.03
4.2
3.4
—
—
—
0
0
20
43
4.75
8.86
1.2
1.1
—
—
—
0
0
12
6
20.30
8.49
1.1
1.0
—
—
—
0
0
192
1274
1.69
8.30
2.4
2.0
2.85
2.93
mg/l
0.20
177
1087
39
140
2.89
8.29
1.6
1.8
—
—
—
0
0
67
313
2.26
8.29
1.6
1.4
—
—
—
0
0
711
6633
3.29
8.14
12.6
9.4
27.84
27.76
u/l
0.04
703
6453
43
165
2.71
8.09
1.7
1.7
—
—
—
0
0
38
137
2.87
8.02
2.0
1.6
—
—
—
0
0
277
2032
1.58
7.93
1.8
1.8
98.97
96.64
pmol/l
0.40
171
1050
21
52
4.13
7.85
1.1
1.1
—
60.50
—
0
6
25
72
3.56
7.60
1.3
1.8
—
—
—
0
0
209
1451
1.62
7.46
2.8
2.8
0.26
0.41
e6/l
0.95
163
1080
166
1090
1.68
7.37
2.6
2.4
5.53
6.80
e6/l
0.56
150
979
30
100
3.09
7.27
1.3
1.3
—
—
—
0
0
30
100
3.09
7.27
1.3
1.4
—
—
—
0
0
221
1568
1.59
7.16
1.9
2.1
184.61
211.59
u/l
0.16
211
1489
302
2306
1.53
7.01
3.5
3.1
—
—
—
0
0
36
136
2.73
7.00
1.6
1.9
—
—
—
0
0
17
27
6.42
6.97
1.1
1.0
—
—
—
0
0
29
100
2.98
6.65
1.5
1.9
—
—
—
0
0
13
15
8.80
6.57
1.2
1.0
—
—
—
0
0
29
101
2.95
6.54
2.1
2.1
139.32
134.17
g/l
0.52
22
75
36
145
2.56
6.20
1.9
2.0
0.59
0.89
g/l
0.18
31
136
17
43
4.02
6.19
1.3
1.1
—
—
—
0
0
352
2828
1.47
6.12
3.3
2.7
93.28
104.32
ug/l
0.44
333
2651
238
1768
1.51
6.11
1.9
3.4
2.34
2.36
mmol/l
1.13
221
1587
206
1494
1.53
5.88
1.7
1.6
—
—
—
0
0
16
32
5.09
5.59
2.2
3.2
364.50
767.56
u/ml
1.73
16
32
27
101
2.74
5.39
1.1
1.1
—
—
—
0
0
128
848
1.62
5.38
2.5
2.4
107.92
122.55
ug/g
0.24
102
672
87
520
1.76
5.37
6.3
8.9
1.26
0.97
mmol/l
0.42
71
417
12
18
6.76
5.27
3.8
1.2
9.58
14.33
u/l
1.43
12
18
17
50
3.46
5.05
2.9
2.9
31.82
33.28
pg
0.83
17
50
15
41
3.71
4.94
1.5
1.8
—
—
—
0
0
13
26
5.07
4.64
1.2
1.1
1407.69
1679.62
miu/ml
0.33
13
26
125
860
1.55
4.45
1.7
2.7
2.43
2.43
mmol/l
0.08
110
755
25
101
2.53
4.34
1.6
1.8
—
—
—
0
0
25
101
2.53
4.34
1.6
1.8
—
—
—
0
0
39
192
2.09
4.32
2.6
1.9
—
—
—
0
0
50
270
1.91
4.29
1.8
1.7
—
—
—
0
0
115
785
1.55
4.24
1.7
1.6
1199.95
1156.61
nmol/l
0.17
95
597
16
51
3.18
4.23
1.1
1.9
—
—
—
0
0
13
30
4.39
4.14
1.5
1.9
—
—
—
0
0
13
30
4.39
4.14
1.5
1.9
—
—
—
0
0
16
53
3.06
3.98
1.6
1.2
—
—
—
0
0
16
53
3.06
3.98
1.4
1.7
—
—
—
0
0
16
53
3.06
3.98
1.4
1.7
—
—
—
0
0
16
53
3.06
3.98
1.4
1.7
—
—
—
0
0
18
64
2.86
3.98
1.4
1.9
—
—
—
0
0
35
171
2.10
3.97
1.8
2.0
0.94
2.67
ug/l
0.55
30
161
597
5495
1.46
3.91
5.4
4.9
38.82
38.80
mmol/mol
0.01
574
5185
16
54
3.01
3.87
1.6
1.2
—
—
—
0
0
8
12
6.73
3.68
1.1
1.0
—
—
—
0
0
11
25
4.45
3.63
1.0
1.8
—
—
—
0
0
113
795
1.50
3.62
1.8
2.3
13.69
14.18
umol/l
0.25
104
741
152
1133
1.43
3.62
1.5
1.4
20.63
21.32
nmol/l
0.26
135
978
19
74
2.61
3.57
1.3
1.2
—
—
—
0
0
10
21
4.81
3.56
1.5
2.1
—
—
—
0
0
10
21
4.81
3.56
1.5
2.1
—
—
—
0
0
10
21
4.81
3.56
1.5
2.1
—
—
—
0
0
130
944
1.46
3.55
3.1
3.4
17.39
570.76
ng/l
2.72
79
635
9
17
5.35
3.52
1.0
1.0
—
—
—
0
0
60
369
1.68
3.39
1.5
1.5
—
—
—
0
0
500
4512
1.34
3.33
3.3
3.1
39.72
45.70
u/l
1.34
477
4289
95
664
1.49
3.14
1.8
2.4
22.86
24.17
%
0.38
85
578
253
2089
1.32
3.14
3.0
3.4
34.33
32.04
u/l
0.26
245
1989
86
590
1.52
3.11
6.0
7.4
104.70
104.24
mmol/l
0.43
86
590
15
56
2.71
3.07
1.4
1.9
—
—
—
0
0
18
74
2.47
3.07
1.2
1.2
—
—
—
0
0
102
728
1.47
3.05
1.8
2.3
2.55
2.40
g/l
1.99
94
677
136
1030
1.39
2.94
1.7
1.6
58974790.98
21469357.29
pmol/l
0.27
117
885
625
5885
1.42
2.86
4.4
3.9
5.62
5.81
mmol/l
5.11
595
5476
19
83
2.32
2.86
1.5
1.8
—
—
—
0
0
17
71
2.43
2.82
1.2
1.2
0.48
0.50
nmol/l
0.16
17
64
62
405
1.58
2.80
3.3
3.5
4.57
4.72
pmol/l
0.63
54
363
33
182
1.85
2.74
2.2
1.8
—
—
—
0
0
11
36
3.09
2.57
2.4
2.8
51190.91
41766.81
ug/l
0.48
11
36
13
50
2.63
2.54
2.3
1.9
14.00
13.31
mg/l
—
5
14
10
31
3.26
2.52
1.5
1.7
—
—
—
0
0
54
354
1.57
2.43
1.5
2.3
13510.17
3245.74
u/l
0.84
12
154
9
27
3.36
2.40
1.6
1.8
—
—
—
0
0
5
8
6.28
2.37
1.0
1.0
—
—
—
0
0
7
17
4.15
2.36
1.1
2.4
—
—
—
0
0
11
39
2.85
2.35
1.1
1.0
—
—
—
0
0
9
28
3.24
2.31
1.6
1.8
—
—
—
0
0
625
5933
1.36
2.30
3.8
3.6
1.32
1.30
mmol/l
0.24
592
5574
15
66
2.30
2.25
1.5
1.7
—
—
—
0
0
13
55
2.39
2.13
1.0
1.0
—
—
—
0
0
88
664
1.37
1.97
2.0
2.7
4.56
7.43
umol/l
2.50
73
569
40
260
1.57
1.91
2.6
1.6
—
—
—
0
0
197
1668
1.25
1.88
3.2
3.2
8.43
8.19
mmol/l
0.28
175
1435
643
6172
1.34
1.84
4.3
4.0
4.89
4.80
mmol/l
1.67
611
5834
15
73
2.08
1.81
1.1
1.1
—
—
—
0
0
102
800
1.32
1.78
2.8
2.6
3.50
2.91
e6/l
0.30
51
404
88
676
1.34
1.77
4.1
3.8
32.10
31.27
%
0.33
72
477
7
24
2.93
1.72
1.7
1.1
—
—
—
0
0
178
1505
1.24
1.71
3.8
3.9
5.60
10.61
mg/mmol
1.19
110
949
15
75
2.02
1.70
1.1
1.1
—
—
—
0
0
7
25
2.82
1.65
2.1
2.1
64.00
55.22
ug/l
—
7
25
639
6151
1.30
1.61
4.1
3.9
1.52
1.47
mmol/l
1.64
610
5795
7
27
2.61
1.51
1.1
1.2
—
—
—
0
0
7
27
2.61
1.51
1.1
1.2
—
—
—
0
0
646
6237
1.30
1.51
4.5
4.3
2.94
2.89
mmol/l
0.93
616
5866
6
21
2.87
1.51
1.8
1.1
—
—
—
0
0
308
2782
1.18
1.47
2.1
2.5
—
—
—
0
0
62
468
1.35
1.43
2.8
2.2
74.56
73.64
ml/min/173m2
0.07
27
182
105
854
1.27
1.42
2.6
2.5
0.72
1.02
e6/l
0.76
54
459
13
67
1.96
1.39
1.0
1.1
—
—
—
0
0
6
23
2.62
1.37
1.2
2.3
—
—
—
0
0
29
192
1.53
1.34
1.1
1.1
—
—
—
0
0
22
137
1.62
1.30
1.1
1.3
—
—
—
0
0
29
194
1.52
1.28
1.1
1.1
—
—
—
0
0
15
84
1.80
1.28
1.1
1.3
—
—
—
0
0
20
123
1.64
1.25
1.2
1.2
—
—
—
0
0
41
297
1.40
1.23
1.3
1.3
126.14
247.53
miu/ml
1.57
13
147
49
366
1.36
1.23
1.1
1.0
—
—
—
0
0
15
86
1.76
1.19
1.1
1.1
—
—
—
0
0
6
26
2.32
1.19
1.0
1.2
—
—
—
0
0
6
26
2.32
1.19
1.0
1.2
—
—
—
0
0
6
26
2.32
1.19
1.2
1.0
—
—
—
0
0
19
118
1.63
1.16
1.6
2.2
3.21
4.66
umol/l
1.40
13
86
15
246
0.60
1.14
1.6
1.4
—
—
—
0
0
15
246
0.60
1.14
1.6
1.4
—
—
—
0
0
43
319
1.37
1.14
2.8
2.6
89.46
122.49
ng/l
0.33
37
286
5
113
0.44
1.13
1.0
1.5
3.94
2.93
ug/l
—
5
101
15
245
0.60
1.13
1.6
1.4
—
—
—
0
0
15
245
0.60
1.13
1.6
1.4
—
—
—
0
0
11
59
1.88
1.08
1.1
1.1
—
—
—
0
0
177
1564
1.17
1.06
1.8
1.7
1.39
1.45
mmol/l
0.35
144
1342
17
106
1.62
1.03
1.9
1.7
4.12
4.96
mmol/24h
0.60
17
92
7
35
2.01
1.00
1.0
1.6
—
1224630.00
iu/ml
—
0
5
18
268
0.66
0.93
1.6
1.5
—
—
—
0
0
19
126
1.52
0.92
2.9
3.4
19.56
84.74
mg/l
0.72
13
102
19
126
1.52
0.92
2.8
3.4
19.01
29.64
mg/l
1.76
13
101
36
472
0.75
0.91
2.4
4.4
2.68
16.74
ug/l
0.89
28
380
64
776
0.81
0.88
1.8
1.6
—
—
—
0
0
12
72
1.68
0.85
1.8
1.8
—
—
—
0
0
12
72
1.68
0.85
1.8
1.8
—
—
—
0
0
8
45
1.79
0.84
1.1
1.5
92.63
75.07
umol/l
—
8
45
8
45
1.79
0.84
2.9
2.2
—
—
—
0
0
22
307
0.71
0.83
1.4
1.4
—
—
—
0
0
6
32
1.88
0.82
1.0
1.1
165.98
169.84
iu/ml
—
6
32
9
53
1.71
0.75
1.3
1.3
168.68
184.43
pmol/l
—
9
53
31
236
1.33
0.75
2.2
1.8
37.71
39.25
nmol/l
0.14
31
230
40
316
1.28
0.75
1.5
1.7
4.40
3.39
mg/l
0.41
35
220
5
24
2.09
0.74
1.8
1.3
28.00
30.63
umol/l
—
5
24
5
25
2.01
0.72
1.8
1.0
52.52
25.34
u/ml
—
5
25
36
454
0.78
0.72
1.5
1.5
—
—
—
0
0
50
412
1.23
0.68
2.8
8.3
7.98
8.00
mmol/l
0.01
50
394
15
103
1.47
0.65
6.0
4.0
18.80
23.85
mg/l
—
5
68
23
172
1.35
0.64
2.0
1.9
4.29
5.13
iu/l
—
7
66
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
14
98
1.44
0.57
1.6
1.9
—
—
—
0
0
147
1344
1.12
0.56
4.0
3.8
1.41
1.92
ug/l
1.20
134
1231
50
423
1.20
0.55
2.3
4.0
2.15
1.88
mmol/l
0.19
44
351
6
38
1.58
0.54
1.2
1.4
—
—
—
0
0
9
61
1.48
0.54
1.1
1.3
—
—
—
0
0
11
74
1.49
0.53
2.4
2.3
—
—
—
0
0
91
811
1.14
0.53
2.5
2.5
0.52
0.66
ug/l
2.17
49
457
16
118
1.36
0.50
1.1
1.0
0.94
1.99
u/ml
—
5
55
31
253
1.24
0.49
3.8
2.5
0.09
0.15
e6/l
0.53
31
244
7
46
1.53
0.48
1.1
1.2
—
—
—
0
0
62
546
1.15
0.44
2.2
2.6
58.23
122.83
u/l
0.33
47
463
17
130
1.31
0.44
1.3
1.4
—
—
—
0
0
148
1375
1.10
0.43
1.8
2.1
—
—
—
0
0
5
32
1.57
0.42
1.4
2.6
50.20
46.38
umol/l
—
5
26
5
32
1.57
0.42
2.2
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
29
343
0.84
0.37
1.3
2.6
16.31
38.84
u/ml
2.21
29
333
8
116
0.69
0.37
1.4
1.2
—
—
—
0
0
123
1143
1.09
0.37
1.9
2.2
—
—
—
0
0
11
81
1.36
0.36
1.1
1.3
—
—
—
0
0
11
81
1.36
0.36
1.1
1.3
—
—
—
0
0
11
81
1.36
0.36
1.1
1.3
—
—
—
0
0
6
44
1.37
0.34
1.0
1.8
—
—
—
0
0
137
1285
1.08
0.33
3.6
3.2
1.02
1.02
kg/l
0.04
14
165
29
247
1.18
0.33
1.6
1.3
10.97
9.35
u/l
0.19
24
202
21
173
1.22
0.33
1.4
1.4
354.89
300.86
ug/g
0.48
11
98
115
1075
1.08
0.31
3.5
3.4
19.76
20.89
%
0.32
40
408
10
130
0.77
0.29
1.5
1.5
—
—
—
0
0
28
241
1.17
0.29
1.1
1.3
—
—
—
0
0
71
653
1.10
0.28
6.8
5.5
—
—
—
0
0
14
114
1.23
0.25
1.3
1.2
10.00
6.41
u/ml
—
8
44
12
97
1.24
0.23
1.2
1.1
—
—
—
0
0
10
79
1.27
0.22
1.1
1.4
—
—
—
0
0
10
79
1.27
0.22
1.1
1.4
—
—
—
0
0
21
182
1.16
0.21
1.8
3.6
1.23
1.37
mg/l
0.52
21
169
0
12
0.00
0.21
0.0
4.0
—
—
—
0
0
10
80
1.25
0.20
1.1
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
50
1.20
0.19
1.2
1.2
—
—
—
0
0
6
50
1.20
0.19
1.2
1.2
—
—
—
0
0
12
99
1.22
0.19
1.0
1.4
—
—
—
0
0
6
51
1.18
0.19
1.2
1.2
—
—
—
0
0
6
51
1.18
0.19
1.2
1.2
—
—
—
0
0
6
51
1.18
0.19
1.2
1.2
—
—
—
0
0
13
152
0.85
0.17
1.2
1.2
—
—
—
0
0
27
245
1.11
0.15
1.4
1.5
—
—
—
0
0
108
1039
1.05
0.14
1.8
2.0
—
—
—
0
0
34
367
0.92
0.14
2.3
2.1
2.15
8.21
ug/l
7.04
34
334
43
402
1.07
0.14
1.2
1.3
25.24
26.66
iu/l
0.10
36
344
10
117
0.85
0.13
1.5
4.4
39.60
36.81
umol/l
—
10
105
13
114
1.14
0.12
1.2
1.2
14.40
4.20
u/ml
—
5
35
101
979
1.04
0.10
1.5
1.8
1.43
1.43
%
0.04
92
883
62
646
0.96
0.10
2.0
1.9
—
—
—
0
0
5
47
1.06
0.09
1.2
1.4
—
—
—
0
0
20
217
0.92
0.09
1.5
1.5
—
—
—
0
0
6
57
1.05
0.08
1.3
1.2
1.43
1.47
nmol/l
—
6
52
20
215
0.93
0.07
1.5
2.2
93.65
91.73
%
0.16
20
207
9
86
1.05
0.07
1.1
1.1
110.89
96.20
%
—
9
79
12
132
0.91
0.06
2.1
1.4
0.24
0.35
nmol/l
—
7
108
27
281
0.96
0.04
1.5
1.5
—
—
—
0
0
123
1245
0.99
0.03
1.6
1.4
—
—
—
0
0
11
118
0.93
0.03
1.1
1.1
—
—
—
0
0
30
292
1.03
0.02
2.3
1.9
—
—
—
0
0
36
367
0.98
0.01
2.6
3.9
79.40
78.90
ng/l
0.01
31
336
17
164
1.04
0.00
1.1
1.2
—
—
—
0
0
12
115
1.04
0.00
2.6
1.8
—
—
—
0
0
13
125
1.04
0.00
1.7
2.3
8.70
153.92
ug/min
—
7
75
14
135
1.04
0.00
1.1
1.4
113.00
105.15
u/ml
—
5
26
11
106
1.04
0.00
1.0
3.6
—
2563.00
—
0
11
16
156
1.03
0.00
1.1
1.3
202.44
245.49
u/ml
—
9
94
16
164
0.98
0.00
1.4
1.5
—
—
—
0
0
11
112
0.98
0.00
1.5
1.9
13.36
13.08
%
0.90
11
112
52
516
1.01
0.00
1.7
1.8
—
—
—
0
0
41
408
1.01
0.00
1.2
1.3
—
—
—
0
0
11
109
1.01
0.00
1.1
1.1
119.82
116.75
%
0.16
11
99
5
54
0.93
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
19
190
1.00
-0.00
1.6
1.7
—
—
—
0
0
5
50
1.00
-0.00
1.2
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
8.50
—
0
7
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
1338.20
—
0
5
0
5
0.00
-0.00
0.0
5.6
—
27.60
—
0
5
0
5
0.00
-0.00
0.0
2.2
—
13.56
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint RX_ASTMA_BIOL and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have RX_ASTMA_BIOL.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: RX_ASTMA_BIOL – Biological medicines for asthma
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data