auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1140 |
4. Check minimum number of eventsNone |
1140 |
5. Include endpointsNone |
1140 |
6. Filter based on genotype QC (FinnGen only) |
1095 |
Control definitions (FinnGen only)
- Control exclude
- H8_MIDDLEMASTOID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H65-H75
- Name in latin
- Aliae morbositates tubae auditivae
Similar endpoints
↥List of similar endpoints to
Other disorders of Eustachian tube
based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6062 | 3566 | 2467 |
| Only index persons | 5812 | 3458 | 2354 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.07 |
| Only index persons | 0.11 | 0.13 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 48.24 | 47.07 | 49.93 |
| Only index persons | 48.07 | 46.99 | 49.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1095 | 714 | 381 |
| Unadjusted period prevalence (%) | 0.23 | 0.25 | 0.17 |
| Median age at first event (years) | 55.40 | 51.81 | 62.13 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1140
- Matched controls
- 11400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
175.2
307.7
165
11
H69.9
ICD-10 Finland
Eustachian tube disorder, unspecified
254.6
307.7
225
11
H69.8
ICD-10 Finland
Other specified disorders of Eustachian tube
438.0
307.7
360
12
H69.0
ICD-10 Finland
Patulous Eustachian tube
1083.7
307.7
583
11
UDC00
NOMESCO Finland
Ear microscopy
9.9
212.5
281
365
Z01.1
ICD-10 Finland
Examination of ears and hearing
6.8
193.5
397
833
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
51.9
180.0
104
22
DFF00
NOMESCO Finland
Pure tone audiometry
7.3
175.0
311
560
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
22.9
115.0
85
40
H66.0
ICD-10 Finland
Acute suppurative otitis media
7.0
104.6
174
285
H66.9
ICD-10 Finland
Otitis media, unspecified
7.0
91.8
150
240
UDH02
NOMESCO Finland
Rhinopharyngoscopy
5.5
85.9
185
387
DC1AD
NOMESCO Finland
Temporalbone CT
45.5
80.8
48
11
H92.0
ICD-10 Finland
Otalgia
5.7
80.4
163
322
H65.3
ICD-10 Finland
Chronic mucoid otitis media
147.1
78.1
82
6
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
139.4
73.9
78
6
H65.2
ICD-10 Finland
Chronic serous otitis media
93.2
63.7
70
8
H65.0
ICD-10 Finland
Acute serous otitis media
18.1
57.8
47
27
R01AD09
ATC
mometasone; nasal
2.7
56.8
671
3971
H29
ICPC
Ear symptom/complaint other
3.5
52.7
208
678
R01AD12
ATC
fluticasone furoate; nasal
2.6
50.2
483
2549
R01AD08
ATC
fluticasone; nasal
2.5
45.3
429
2224
R01AD58
ATC
fluticasone, combinations; nasal
2.5
43.1
378
1884
DGW00
NOMESCO Finland
Dilatation of eustachian tube
+∞
38.8
37
*
H01
ICPC
Ear pain/earache
3.0
38.6
194
724
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
37.7
36
*
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
11.5
37.3
39
35
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.7
35.5
235
1013
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.9
34.6
110
307
H93.1
ICD-10 Finland
Tinnitus
3.5
33.3
124
385
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
31.4
30
*
TDA90
NOMESCO Finland
Removal wax from ear
9.1
30.8
38
43
H13
ICPC
Plugged feeling ear
2.4
29.6
257
1247
4122
FHL
Tympanostomy (tympanic tube)
102.7
27.8
30
*
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
27.2
26
*
DFF15
NOMESCO Finland
Speech audiometry
3.8
26.9
84
231
UDM02
NOMESCO Finland
Sinoscopy
5.5
25.1
49
92
DCD00
NOMESCO Finland
Myringoplasty
255.5
24.8
25
*
H02
ICPC
Hearing complaint
2.4
24.3
182
821
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
23.9
453
2917
SPAT1043
SPAT
Audiometry
2.7
23.9
145
592
H02AB06
ATC
prednisolone; systemic
1.9
23.8
564
3902
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
7.3
23.0
34
48
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.5
22.9
56
128
N07CA01
ATC
betahistine; oral
3.0
22.7
107
381
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.9
22.1
108
393
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.8
22.0
119
457
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
25.6
21.8
30
12
H91.9
ICD-10 Finland
Hearing loss, unspecified
3.4
21.5
81
252
J31.0
ICD-10 Finland
Chronic rhinitis
2.6
20.9
128
524
A02BC05
ATC
esomeprazole; systemic
1.8
20.7
476
3221
N03AX16
ATC
[U] pregabalin
2.0
19.9
287
1668
J01FA10
ATC
azithromycin; systemic
1.8
19.2
690
5278
A02BC02
ATC
pantoprazole; systemic
1.8
19.0
774
6132
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.6
18.9
64
186
R01BA52
ATC
pseudoephedrine, combinations; oral
1.8
18.7
362
2308
R42
ICD-10 Finland
Dizziness and giddiness
2.0
18.6
266
1537
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
18.3
300
1813
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
17.8
17
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
17.7
614
4607
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.8
17.5
324
2031
R13
ICD-10 Finland
Dysphagia
2.7
17.5
99
389
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
7.5
17.4
25
34
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.7
17.1
56
159
J02AC01
ATC
fluconazole; systemic
1.7
16.8
476
3362
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
16.5
270
1623
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.5
16.5
57
168
H60.3
ICD-10 Finland
Other infective otitis externa
4.5
16.5
40
91
J01AA02
ATC
doxycycline; systemic
1.8
16.0
872
7312
M03BX02
ATC
tizanidine; oral
1.7
15.7
718
5719
G44.2
ICD-10 Finland
Tension-type headache
2.0
15.7
186
1002
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
4.3
15.6
40
95
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
15.5
303
1921
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
15.0
15.4
25
17
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
15.3
323
2091
J01CA04
ATC
amoxicillin; systemic
1.9
15.3
944
8152
J01DB01
ATC
cefalexin; oral
1.9
15.3
946
8176
R51.80
ICD-10 Finland
Headache
1.9
15.2
203
1140
H60.8
ICD-10 Finland
Other otitis externa
3.6
15.0
49
139
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
14.9
103
445
H66
ICD-10 Finland
Suppurative and unspecified otitis media
4.1
14.9
41
103
EMB30
NOMESCO Finland
Adenotomy
5.6
14.8
28
51
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
14.6
14
*
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
6.4
14.6
24
38
M79.6
ICD-10 Finland
Pain in limb
1.6
14.4
480
3501
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
13.6
14.2
24
18
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.2
14.2
126
607
H69
ICD-10 Finland
Other disorders of Eustachian tube
43.1
14.1
17
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
13.9
496
3669
L01
ICPC
Neck symptom/complaint
1.9
13.9
193
1096
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
17.8
13.9
21
12
SPAT1044
SPAT
Tympanometry
4.2
13.7
36
87
J01MA02
ATC
ciprofloxacin; systemic
1.6
13.6
409
2894
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
13.6
13
*
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
34.5
13.5
17
5
UKC02
NOMESCO Finland
Cystoscopy
2.0
13.5
172
949
N06AX11
ATC
mirtazapine; oral
1.7
13.4
383
2675
A02BC03
ATC
lansoprazole; oral
1.7
13.2
324
2174
R06AX27
ATC
desloratadine; oral
1.7
13.0
340
2316
R03AC02
ATC
salbutamol; inhalant
1.6
13.0
628
4964
N03AX12
ATC
[U] gabapentin; oral
1.9
13.0
193
1118
R20.2
ICD-10 Finland
Paraesthesia of skin
2.4
13.0
95
421
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
13.0
287
1870
N17
ICPC
Vertigo/dizziness
2.0
13.0
145
762
H71
ICPC
Acute otitis media/myringitis
5.7
12.9
24
43
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
50.6
12.9
15
*
EMB10
NOMESCO Finland
Tonsillectomy
2.6
12.8
78
318
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
12.8
459
3382
ZZG00
NOMESCO Finland
Graft of cartilage
32.4
12.6
16
5
DGW99
NOMESCO Finland
Other operation on eustachian tube
+∞
12.5
12
*
DGB00
NOMESCO Finland
Obliteration of eustachian tube
+∞
12.5
12
*
J30.0
ICD-10 Finland
Vasomotor rhinitis
3.6
12.3
41
118
H91.8
ICD-10 Finland
Other specified hearing loss
5.9
12.3
22
38
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
12.1
563
4385
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
11.5
142
773
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
121.2
11.4
12
*
Z71.8
ICD-10 Finland
Other specified counselling
1.6
11.3
353
2498
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.5
11.2
68
277
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
11.2
193
1169
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
11.1
471
3572
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.2
11.1
98
471
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
11.0
467
3538
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
2.0
11.0
122
638
Z01.2
ICD-10 Finland
Dental examination
1.5
10.9
508
3926
4451
FHL
Guitar cutting
4.2
10.9
29
71
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
10.8
464
3521
R01AD11
ATC
triamcinolone; nasal
2.1
10.8
107
537
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.4
10.8
77
338
DHB50
NOMESCO Finland
Turbinoplasty
3.3
10.8
40
124
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
10.7
233
1504
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
60.6
10.6
12
*
Z97.4
ICD-10 Finland
Presence of external hearing-aid
2.8
10.6
54
201
H04
ICPC
Ear discharge
3.0
10.6
46
157
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
10.5
170
1008
H27
ICPC
Fear of ear disease
4.9
10.5
23
48
A04
ICPC
Weakness/tiredness general
1.8
10.5
163
955
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
10.4
10
*
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
10.4
10
*
R09
ICPC
Sinus symptom/complaint
2.0
10.4
110
567
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
10.2
280
1914
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
2.6
10.2
58
229
J35.0
ICD-10 Finland
Chronic tonsillitis
2.4
10.1
69
297
R06.0
ICD-10 Finland
Dyspnoea
1.6
9.9
284
1960
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
2.4
9.8
67
288
R02
ICPC
Shortness of breath/dyspnoea
1.9
9.7
140
800
J01DA01
ATC
[U] cefalexin
1.5
9.6
671
5583
R06AE07
ATC
cetirizine; oral
1.5
9.6
483
3765
UJF30
NOMESCO Finland
Ileoscopy through colon
2.0
9.5
114
613
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
9.5
204
1309
F51.0
ICD-10 Finland
Nonorganic insomnia
1.7
9.4
188
1182
M25.5
ICD-10 Finland
Pain in joint
1.5
9.4
358
2630
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
9.4
9
*
H73.1
ICD-10 Finland
Chronic myringitis
+∞
9.4
9
*
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
9.4
9
*
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.5
9.4
601
4907
ZXA10
NOMESCO Finland
Bilateral
1.7
9.3
185
1161
DAX08
NOMESCO Finland
Fitting of hearing aid
2.5
9.3
59
245
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.7
9.2
48
181
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.0
9.2
41
142
H93.9
ICD-10 Finland
Disorder of ear, unspecified
13.8
9.2
15
11
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
3.1
9.2
37
121
L08
ICPC
Shoulder symptom/complaint
1.6
9.1
234
1569
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
9.1
306
2186
N02BE01
ATC
paracetamol; systemic, rectal
1.7
9.1
988
8998
R03DC03
ATC
montelukast; oral
1.7
9.0
188
1195
S18
ICPC
Laceration/cut
1.5
8.9
480
3774
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
8.9
782
6765
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.1
8.8
89
450
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
8.8
130
748
H61.2
ICD-10 Finland
Impacted cerumen
2.2
8.8
72
335
A02BA02
ATC
ranitidine; systemic
1.7
8.8
201
1308
J34.2
ICD-10 Finland
Deviated nasal septum
2.3
8.8
63
277
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
8.8
111
608
N02AX02
ATC
tramadol; systemic, rectal
1.5
8.8
441
3419
L03
ICPC
Low back symptom/complaint
1.5
8.7
302
2169
H02AB04
ATC
methylprednisolone; systemic
1.7
8.7
153
928
DCD10
NOMESCO Finland
Tympanoplasty
50.4
8.7
10
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
8.7
290
2066
SPAT1263
SPAT
Sampling
1.5
8.6
443
3448
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.6
8.6
48
188
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
8.5
113
630
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.8
8.4
124
713
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.0
8.4
90
465
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
8.3
8
*
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
8.3
8
*
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.7
8.3
179
1147
G50.1
ICD-10 Finland
Atypical facial pain
3.7
8.3
26
72
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
8.3
295
2127
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
8.3
114
642
R00.2
ICD-10 Finland
Palpitations
2.0
8.3
95
504
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
8.3
197
1296
XKD00
NOMESCO Finland
Uroflowmetry
1.8
8.2
132
779
SFA10
NOMESCO Finland
One-surface restoration
1.4
8.2
600
4973
R05
ICD-10 Finland
Cough
1.6
8.1
226
1542
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.8
8.1
39
141
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
8.1
102
558
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
8.1
200
1327
G04CA02
ATC
tamsulosin; oral
1.6
8.1
190
1245
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
8.1
374
2844
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
6.3
8.0
20
32
DFF10
NOMESCO Finland
Measurement of acoustic impedance (tympanometry and reflex testing)
22.2
8.0
11
5
L17
ICPC
Foot/toe symptom/complaint
1.5
8.0
310
2273
D06
ICPC
Abdominal pain localized other
1.9
7.9
95
511
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.5
7.9
254
1790
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.4
7.9
52
221
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
7.8
430
3375
M01AH03
ATC
valdecoxib; oral
2.2
7.7
67
320
J01CA08
ATC
pivmecillinam; oral
1.4
7.7
444
3512
A01
ICPC
Pain general/multiple sites
1.9
7.7
101
561
XF402
NOMESCO Finland
ECG with work load test
1.8
7.6
111
636
K30
ICD-10 Finland
Functional dyspepsia
1.8
7.6
126
750
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
4.0
7.6
21
53
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.8
7.6
106
599
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
7.6
54
237
R53
ICD-10 Finland
Malaise and fatigue
1.5
7.6
248
1752
M54.6
ICD-10 Finland
Pain in thoracic spine
1.9
7.6
91
490
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
7.5
788
6918
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
7.5
259
1852
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
7.5
137
840
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.7
7.4
128
772
U01
ICPC
Dysuria/painful urination
1.9
7.4
91
494
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
7.4
157
1003
R06.5
ICD-10 Finland
Mouth breathing
1.9
7.3
96
533
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
7.3
7
*
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
7.3
7
*
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
7.3
7
*
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
7.3
7
*
3818X
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Other disorders of Eustachian tube
+∞
7.3
7
*
N05CF01
ATC
zopiclone; oral
1.5
7.3
323
2427
M54.8
ICD-10 Finland
Other dorsalgia
2.3
7.2
53
236
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
7.2
116
685
R52.9
ICD-10 Finland
Pain, unspecified
1.8
7.2
105
602
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
2.8
7.1
34
123
SPAT1041
SPAT
Comprehensive hearing test
4.1
7.1
19
47
M31.3
ICD-10 Finland
Wegener granulomatosis
12.1
7.1
12
10
H60
ICD-10 Finland
Otitis externa
2.1
7.0
63
305
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
3.1
7.0
28
91
J01FA06
ATC
roxithromycin; oral
1.4
7.0
412
3256
K08.80
ICD-10 Finland
Toothache NOS
1.8
7.0
101
578
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.0
7.0
77
403
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
3.0
7.0
29
97
M03BC51
ATC
orphenadrine, combinations; systemic
1.5
6.9
287
2126
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.5
6.9
41
166
M24.2
ICD-10 Finland
Disorder of ligament
3.6
6.9
22
62
M01AB05
ATC
diclofenac; systemic, rectal
1.4
6.9
699
6053
L04AX03
ATC
methotrexate; systemic
1.8
6.9
105
611
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.3
6.9
51
229
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
6.8
91
509
H61.8
ICD-10 Finland
Other specified disorders of external ear
5.7
6.8
18
32
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
40.3
6.8
8
*
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
40.3
6.8
8
*
N06AX21
ATC
duloxetine; oral
1.7
6.7
131
816
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.0
6.7
75
394
R01AD01
ATC
beclometasone; nasal
1.6
6.7
163
1074
H53.1
ICD-10 Finland
Subjective visual disturbances
2.0
6.7
72
373
J01EA01
ATC
trimethoprim; systemic
1.5
6.7
271
1995
SPAT1153
SPAT
Removal of sutures
1.4
6.7
317
2405
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
6.6
103
604
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.5
6.6
40
164
A03
ICPC
Fever
1.6
6.6
180
1221
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
6.6
100
582
SPAT1260
SPAT
Consultation of another employee
1.6
6.5
175
1181
M01AH05
ATC
etoricoxib; oral
1.4
6.5
657
5659
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
6.5
124
769
4141
FHL
Myringoplasty (also for reasons other than inflammation)
70.2
6.4
7
*
ZXA05
NOMESCO Finland
Left side
1.5
6.4
237
1713
F45.8
ICD-10 Finland
Other somatoform disorders
1.9
6.4
83
459
R01AD05
ATC
budesonide; nasal
1.9
6.4
85
474
J01FA09
ATC
clarithromycin; systemic
1.4
6.4
324
2488
H81.0
ICD-10 Finland
Ménière disease
2.9
6.3
28
97
M02AA10
ATC
ketoprofen; topical
1.6
6.3
155
1024
H60.4
ICD-10 Finland
Cholesteatoma of external ear
18.1
6.3
9
5
XQ800
NOMESCO Finland
Prick test
1.8
6.3
84
470
R05
ICPC
Cough
1.5
6.1
251
1850
S21
ICPC
Skin texture symptom/complaint
1.6
6.1
142
926
Z01.9
ICD-10 Finland
Special examination, unspecified
2.0
6.1
66
344
R07.3
ICD-10 Finland
Other chest pain
1.7
6.1
107
649
S02CA02
ATC
flumetasone and antiinfectives; otic
2.1
6.1
56
275
M01AC06
ATC
meloxicam; systemic, rectal
1.4
6.1
367
2900
M01AH02
ATC
rofecoxib; oral
1.7
6.0
121
760
ULC02
NOMESCO Finland
Hysteroscopy
2.1
6.0
54
262
R06AX13
ATC
loratadine; oral
1.6
6.0
161
1086
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
837
6938
1.78
15.98
5.3
4.0
10.61
11.52
mm/h
1.11
792
6425
579
4385
1.65
15.19
7.5
6.3
1.22
1.21
mmol/l
0.53
500
3736
406
2867
1.65
13.65
2.7
2.4
58.55
88.20
u/l
0.54
380
2657
513
3872
1.59
12.92
2.5
2.2
78.22
76.51
nmol/l
0.72
471
3485
833
7087
1.65
12.36
9.1
7.2
75.47
77.03
u/l
0.60
802
6668
1039
9433
2.15
12.35
17.4
12.8
19.12
22.49
mg/l
3.44
834
7394
576
4528
1.55
11.75
7.3
5.6
29.09
28.38
%
0.84
546
4257
518
4002
1.54
11.27
15.4
13.1
1.31
1.21
inr
1.59
157
1187
567
4468
1.54
11.26
7.2
5.4
55.98
56.80
%
1.00
535
4198
248
1613
1.69
11.11
1.3
1.3
15.51
9.89
u/ml
0.54
88
634
492
3775
1.53
10.95
5.3
4.6
36.06
35.87
g/l
0.32
456
3528
858
7440
1.62
10.89
4.7
4.1
14.66
14.68
pmol/l
0.06
796
6819
511
3975
1.52
10.55
6.6
5.6
1.22
1.21
mmol/l
0.69
473
3638
247
1633
1.65
10.32
4.0
3.7
126.61
371.16
ng/l
2.48
179
1214
589
4734
1.51
10.31
6.9
6.0
10.91
11.21
umol/l
0.32
568
4505
657
5402
1.51
10.30
10.1
8.7
3.97
4.04
e9/l
0.24
604
4754
252
1693
1.63
9.83
1.3
1.3
18.40
31.61
iu/ml
3.18
81
547
1044
9639
1.99
9.60
18.9
14.3
139.69
139.67
mmol/l
0.14
1028
9390
1046
9664
2.00
9.59
19.2
14.4
3.95
3.95
mmol/l
0.04
1028
9394
977
8842
1.73
9.58
5.7
4.8
2.83
1.87
mu/l
0.51
917
8164
644
5336
1.48
9.28
5.4
4.4
6.53
6.63
mmol/l
0.55
602
4968
359
2649
1.52
9.21
2.2
2.0
117.57
239.26
u/l
2.75
328
2499
144
856
1.78
8.79
2.9
2.1
349.55
372.98
nmol/l
0.87
128
790
116
654
1.86
8.41
2.3
2.4
18.15
24.58
au/ml
—
10
59
429
3335
1.46
8.31
3.4
3.4
37.11
49.77
ng/l
0.32
263
2193
1074
10089
2.11
8.26
12.6
9.8
25.90
25.96
u/l
0.03
1054
9752
107
596
1.88
8.05
1.7
1.7
—
—
—
0
0
456
3604
1.44
8.01
2.1
1.9
96.34
95.29
pmol/l
0.19
246
1845
59
268
2.27
7.69
1.5
1.4
295.20
290.46
ug/g
0.06
39
150
177
1184
1.59
6.87
1.8
2.3
73.27
123.02
ug/g
3.77
138
936
521
4303
1.39
6.78
3.3
2.7
99.36
110.48
ug/l
0.93
489
3989
300
2253
1.45
6.70
1.3
1.3
0.86
1.75
u/ml
1.95
77
601
76
405
1.94
6.56
2.0
2.1
38.41
39.69
u/l
0.30
70
367
219
1553
1.51
6.51
1.8
1.7
1145.62
1209.55
nmol/l
0.53
168
1172
107
641
1.74
6.35
2.9
2.9
150.89
168.12
ng/l
0.18
102
585
388
3081
1.39
6.26
4.0
3.1
31.88
31.48
u/l
0.04
370
2933
53
255
2.13
6.06
2.0
2.1
10.14
11.83
mg/l
1.07
47
239
1106
10632
2.35
5.97
25.0
18.9
251.65
254.01
e9/l
0.67
1092
10381
1106
10639
2.33
5.83
25.0
18.9
4.47
4.50
e12/l
1.47
1087
10364
559
4743
1.35
5.82
4.3
3.5
0.00
0.01
estimate
0.80
92
870
1106
10641
2.32
5.79
25.1
18.9
6.61
6.67
e9/l
0.41
1088
10359
1105
10628
2.29
5.78
25.2
18.9
40.10
40.15
%
0.09
1026
9977
194
1375
1.50
5.75
2.0
1.8
—
—
—
0
0
725
6407
1.36
5.75
3.6
3.0
43.38
45.05
u/l
0.25
684
6018
1106
10644
2.31
5.74
25.1
19.0
135.02
135.28
g/l
0.26
1098
10493
553
4694
1.35
5.70
5.7
4.7
0.00
0.00
estimate
0.50
95
900
550
4672
1.34
5.61
4.3
3.5
0.00
0.00
estimate
0.75
97
947
268
2035
1.41
5.51
4.1
3.8
1.02
1.02
kg/l
0.11
47
275
111
700
1.65
5.47
3.3
2.5
10.29
10.72
g/l
0.40
103
642
297
2321
1.38
5.11
2.8
2.5
3359.28
5811.30
umol/l
0.61
263
2044
147
1007
1.53
5.11
3.3
2.5
6.47
8.70
umol/l
1.49
124
871
40
187
2.18
4.96
4.8
6.9
105.23
105.40
mmol/l
0.10
35
172
18
56
3.25
4.90
1.3
1.3
—
—
—
0
0
52
270
1.97
4.90
1.1
1.1
4.38
4.02
u/ml
—
8
36
30
125
2.44
4.83
1.2
1.3
—
—
—
0
0
290
2278
1.37
4.80
2.7
2.1
2.59
2.96
mg/l
2.89
253
1938
972
9117
1.45
4.68
4.7
4.3
5.76
5.88
mmol/l
2.68
913
8364
18
58
3.14
4.65
1.4
1.7
—
—
—
0
0
373
3068
1.32
4.49
2.9
3.4
2.34
2.35
mmol/l
0.73
335
2738
50
265
1.93
4.46
2.9
2.7
—
—
—
0
0
714
6410
1.30
4.44
3.5
3.1
—
—
—
0
0
108
714
1.57
4.41
7.8
7.3
8.79
9.13
mmol/l
0.23
103
678
266
2086
1.36
4.41
1.9
1.7
0.86
1.09
mg/l
1.48
197
1581
1003
9486
1.48
4.41
5.2
4.7
2.79
2.80
mmol/l
0.10
938
8830
161
1159
1.45
4.38
3.0
2.4
22.50
23.18
%
0.26
123
988
918
8552
1.38
4.36
5.7
5.4
39.37
39.39
mmol/mol
0.01
861
7964
246
1910
1.37
4.34
1.7
1.5
—
—
—
0
0
989
9336
1.45
4.31
4.7
4.2
4.68
4.71
mmol/l
0.51
932
8728
19
67
2.87
4.24
1.2
1.1
—
2.20
—
0
5
330
2688
1.32
4.21
3.9
3.0
33.75
84.96
e6/l
1.20
264
2064
20
73
2.77
4.20
1.2
1.1
18.00
81.83
u/ml
—
5
6
70
421
1.71
4.17
10.3
10.0
24.09
24.38
mmol/l
0.26
70
412
170
1249
1.42
4.15
2.9
2.3
2.42
2.36
g/l
0.90
152
1156
97
636
1.57
4.11
1.3
1.2
347.75
190.24
u/ml
0.37
90
588
56
319
1.79
4.02
1.9
1.7
—
—
—
0
0
982
9285
1.42
3.98
4.6
4.2
1.49
1.49
mmol/l
0.26
919
8633
36
177
2.07
3.98
2.2
2.1
134.21
128.45
g/l
0.80
24
133
153
1113
1.43
3.94
7.4
5.2
1.02
1.04
mmol/l
0.28
145
1026
131
931
1.46
3.82
7.6
7.6
0.85
1.15
mmol/l
0.37
105
747
33
161
2.08
3.74
1.4
1.5
—
—
—
0
0
15
50
3.03
3.69
1.1
1.0
—
—
—
0
0
131
938
1.45
3.68
8.0
7.5
5.14
5.11
kpa
0.10
123
902
131
938
1.45
3.68
8.0
7.5
13.57
12.30
kpa
1.82
124
904
892
8337
1.32
3.67
20.0
15.2
15.29
14.73
%
1.70
880
8190
382
3224
1.28
3.64
3.9
3.0
—
—
—
0
0
57
337
1.73
3.64
4.3
4.9
1.68
1.60
%
0.24
51
319
510
4464
1.26
3.56
2.7
2.4
—
—
—
0
0
77
497
1.59
3.52
3.2
3.4
1.15
1.76
mmol/l
0.90
64
381
12
31
3.90
3.49
1.1
1.1
—
—
—
0
0
56
334
1.71
3.48
2.0
1.8
—
—
—
0
0
88
590
1.53
3.42
2.9
2.1
13.04
12.65
nmol/l
0.15
76
532
79
518
1.56
3.39
1.1
1.0
—
—
—
0
0
99
683
1.49
3.37
3.8
3.5
73.26
80.51
ng/l
0.68
86
609
226
1798
1.32
3.34
1.6
1.4
—
—
—
0
0
45
255
1.80
3.34
1.1
1.1
—
—
—
0
0
946
8951
1.33
3.31
4.2
3.8
1.25
1.28
mmol/l
0.68
884
8276
37
198
1.90
3.28
1.1
1.2
2.40
6.04
u/ml
—
5
16
287
2367
1.28
3.23
2.7
2.9
958.90
1095.16
ng/l
0.40
254
2000
231
1852
1.31
3.22
3.1
2.4
6.57
6.71
e6/l
0.03
215
1674
254
2066
1.30
3.18
1.6
1.5
21.40
21.02
nmol/l
0.15
229
1759
148
1113
1.38
3.16
4.3
4.2
33.67
32.14
%
1.08
115
767
181
1405
1.34
3.16
4.3
3.1
0.82
0.82
mmol/l
0.01
172
1322
943
8936
1.32
3.13
15.7
11.7
83.38
83.73
ml/min/173m2
0.19
808
7309
51
306
1.70
3.12
1.9
1.7
—
—
—
0
0
239
1938
1.30
3.06
1.5
1.4
2.37
2.38
g/l
0.03
146
1192
269
2227
1.27
2.92
2.6
2.1
—
—
—
0
0
292
2448
1.26
2.84
3.7
2.9
0.29
0.45
e6/l
1.32
226
1847
175
1375
1.32
2.82
2.9
2.3
13.93
13.46
umol/l
0.38
158
1275
31
166
1.89
2.78
1.4
1.4
18.13
24.31
u/l
0.66
23
139
170
1334
1.32
2.76
2.6
2.0
30.67
29.65
s
0.62
163
1295
128
963
1.37
2.74
1.9
1.7
—
—
—
0
0
416
3646
1.22
2.67
4.6
3.6
—
—
—
0
0
127
959
1.36
2.67
1.9
1.7
—
—
—
0
0
70
474
1.51
2.65
1.9
1.6
—
—
—
0
0
95
686
1.42
2.60
2.0
2.7
66.24
66.74
g/l
0.22
87
633
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
41
246
1.69
2.56
3.7
3.0
0.31
0.39
u/ml
1.29
24
137
174
1385
1.30
2.56
3.5
2.7
2.69
2.77
e6/l
0.05
103
727
10
31
3.25
2.52
5.7
4.6
—
—
—
0
0
31
173
1.81
2.48
4.1
5.5
234.00
336.04
iu/ml
—
7
24
44
272
1.64
2.47
1.3
1.3
—
—
—
0
0
278
2362
1.23
2.37
5.3
4.7
2.24
2.74
ug/l
0.52
257
2126
66
454
1.48
2.35
2.1
2.2
5398.36
3596.33
u/l
0.21
15
195
29
162
1.81
2.32
1.5
1.5
—
—
—
0
0
46
293
1.59
2.31
1.4
2.1
10.22
10.51
g/l
0.15
39
268
53
350
1.54
2.28
1.7
2.1
1.42
1.52
g/l
0.38
43
307
50
326
1.56
2.28
3.5
3.8
24.68
24.98
mmol/l
0.42
50
309
34
201
1.71
2.26
1.3
1.6
—
—
—
0
0
26
142
1.85
2.24
1.1
1.0
5.29
1.50
u/ml
0.44
12
67
41
257
1.62
2.20
1.2
1.2
4.89
2.77
u/ml
—
8
27
266
2270
1.22
2.16
5.3
3.6
93.53
92.03
%
0.42
255
2206
22
115
1.93
2.16
1.3
1.5
—
—
—
0
0
181
1482
1.26
2.14
3.1
2.5
0.87
1.06
e6/l
0.63
110
822
87
643
1.38
2.12
2.5
3.4
4.42
4.56
pmol/l
0.79
76
568
41
261
1.59
2.09
1.2
1.2
10.34
9.40
u/ml
—
10
43
22
117
1.90
2.07
1.1
1.5
—
—
—
0
0
27
154
1.77
2.05
1.2
1.4
—
—
—
0
0
15
300
0.49
2.04
3.2
3.9
1.20
1.28
mmol/l
0.22
15
292
8
26
3.09
2.01
1.1
1.0
—
—
—
0
0
45
296
1.54
2.00
1.7
1.6
0.01
0.08
iu/ml
—
9
51
10
39
2.58
1.94
1.1
1.5
—
—
—
0
0
10
39
2.58
1.94
1.1
1.5
—
—
—
0
0
288
2503
1.20
1.93
1.7
1.6
1.33
1.37
mmol/l
0.30
242
2110
34
211
1.63
1.93
1.4
1.6
5414.82
15020.95
e6/l
1.66
22
158
23
129
1.80
1.86
1.3
1.2
—
—
—
0
0
23
130
1.79
1.82
1.2
1.1
—
—
—
0
0
37
239
1.57
1.80
2.4
1.6
37.22
42.12
nmol/l
0.32
37
229
99
771
1.31
1.75
9.4
8.3
122.32
121.12
g/l
0.24
94
754
29
179
1.64
1.71
1.3
1.4
—
—
—
0
0
45
308
1.48
1.70
1.7
1.6
—
—
—
0
0
0
48
0.00
1.70
0.0
2.9
—
—
—
0
0
106
838
1.29
1.69
3.0
2.3
32.53
36.52
u/l
0.58
89
701
46
317
1.47
1.69
1.4
2.1
7.35
7.36
g/l
0.01
39
293
46
317
1.47
1.69
1.4
2.1
—
—
—
0
0
46
317
1.47
1.69
1.4
2.1
3.54
3.62
g/l
0.16
39
293
110
876
1.28
1.66
4.3
4.3
6.20
24.94
ug/l
1.23
88
722
8
31
2.59
1.66
1.6
1.4
—
—
—
0
0
103
814
1.29
1.65
3.3
2.2
0.21
0.22
g/l
0.50
97
769
16
83
1.94
1.65
4.1
3.5
—
—
—
0
0
23
136
1.71
1.59
1.1
1.4
—
—
—
0
0
35
231
1.53
1.58
1.1
1.2
—
—
—
0
0
220
1906
1.19
1.52
1.7
1.7
121311918.05
31704683.27
pmol/l
0.52
183
1596
219
1897
1.19
1.52
4.6
4.2
21.70
21.29
%
0.15
111
862
55
401
1.39
1.52
2.1
1.5
357.78
284.86
mu/l
0.81
49
357
7
27
2.60
1.51
1.4
1.8
45.96
53.13
ug/l
—
7
27
43
300
1.45
1.51
1.4
2.2
3.02
2.96
g/l
0.13
36
276
6
21
2.87
1.50
1.0
1.2
—
—
—
0
0
94
745
1.29
1.49
1.2
1.2
108.41
138.98
iu/ml
0.43
48
301
14
255
0.54
1.48
3.3
4.1
3.89
3.87
mmol/l
0.06
14
250
27
171
1.59
1.47
2.6
1.7
163.00
207.95
pmol/l
1.85
27
162
10
45
2.23
1.46
1.0
1.2
—
83.00
%
—
0
7
9
38
2.38
1.45
1.4
2.3
—
—
—
0
0
190
1633
1.20
1.44
2.9
2.9
2.43
2.45
mmol/l
1.24
165
1445
41
288
1.44
1.40
1.5
1.3
—
—
—
0
0
6
23
2.62
1.37
1.0
1.2
—
—
—
0
0
87
1083
0.79
1.36
5.0
6.8
—
—
—
0
0
10
47
2.14
1.34
1.4
1.2
10.00
10.90
u/l
—
10
42
9
42
2.15
1.34
1.0
1.4
—
—
—
0
0
9
42
2.15
1.34
1.0
1.4
—
—
—
0
0
157
1337
1.20
1.32
2.4
2.2
—
—
—
0
0
23
144
1.61
1.32
1.1
1.2
—
—
—
0
0
9
43
2.10
1.30
1.2
1.6
—
—
—
0
0
9
43
2.10
1.30
1.2
1.6
—
—
—
0
0
5
18
2.79
1.28
1.0
1.1
101.40
99.72
%
—
5
18
10
48
2.09
1.28
1.0
1.4
—
—
—
0
0
10
48
2.09
1.28
1.0
1.4
—
—
—
0
0
84
674
1.27
1.24
1.8
2.4
5.95
6.94
ug/l
0.28
74
604
26
171
1.53
1.24
1.1
1.1
10.29
6.76
u/ml
0.27
15
87
37
263
1.42
1.22
3.9
3.7
43.01
74.08
mg/l
0.62
32
211
37
263
1.42
1.22
3.9
3.7
114.53
42.88
mg/l
0.38
32
212
26
172
1.52
1.21
1.1
1.1
—
10.04
—
0
13
143
1219
1.20
1.21
2.3
2.0
—
—
—
0
0
22
140
1.58
1.20
1.1
1.0
5.14
4.95
u/ml
0.02
11
65
66
516
1.30
1.20
1.3
1.3
23.13
28.33
iu/l
0.72
61
439
36
256
1.42
1.19
1.5
2.1
37.41
38.07
g/l
0.21
29
232
30
206
1.47
1.18
1.3
1.6
—
—
—
0
0
23
149
1.55
1.18
1.3
1.6
—
—
—
0
0
11
57
1.94
1.17
1.3
1.5
—
—
—
0
0
49
369
1.34
1.16
1.5
1.4
—
—
—
0
0
29
200
1.46
1.13
1.3
1.6
—
—
—
0
0
22
143
1.55
1.12
1.2
1.1
—
—
—
0
0
16
96
1.68
1.10
1.1
1.1
—
—
—
0
0
7
31
2.27
1.10
1.3
1.8
—
—
—
0
0
7
31
2.27
1.10
1.3
1.8
—
—
—
0
0
38
278
1.38
1.09
1.7
2.4
0.77
0.92
g/l
0.07
31
250
7
32
2.19
1.08
1.3
1.7
—
—
—
0
0
66
526
1.27
1.06
1.4
1.5
—
—
—
0
0
17
106
1.61
1.03
1.2
1.1
—
—
—
0
0
27
188
1.45
1.02
1.3
1.1
6.68
3.02
u/ml
0.34
18
99
38
283
1.35
0.99
1.2
1.2
—
—
—
0
0
9
49
1.84
0.98
1.3
1.3
160.07
175.54
pmol/l
—
9
49
21
140
1.51
0.98
1.2
1.5
—
—
—
0
0
21
140
1.51
0.98
1.2
1.5
—
—
—
0
0
15
92
1.64
0.97
1.0
1.1
—
—
—
0
0
277
2528
1.13
0.96
5.3
3.8
0.00
0.01
estimate
1.08
91
878
136
1181
1.17
0.96
1.6
1.8
1.41
1.43
%
0.11
117
1055
29
209
1.40
0.93
1.5
1.4
—
—
—
0
0
16
102
1.58
0.90
1.1
1.1
—
—
—
0
0
6
29
2.07
0.89
3.0
1.8
—
—
—
0
0
84
704
1.21
0.89
1.8
2.4
73.93
68.85
ml/min/173m2
0.58
38
289
74
888
0.82
0.88
1.5
1.7
—
—
—
0
0
15
95
1.59
0.87
1.5
1.6
—
—
—
0
0
44
344
1.29
0.85
1.5
1.3
220.87
254.82
miu/ml
0.28
25
172
104
894
1.18
0.85
2.9
3.0
—
—
—
0
0
67
553
1.22
0.83
1.4
1.3
—
—
—
0
0
37
284
1.31
0.82
1.2
1.2
—
—
—
0
0
8
46
1.74
0.82
1.4
1.6
—
—
—
0
0
8
46
1.74
0.82
1.4
1.6
—
—
—
0
0
302
2796
1.11
0.82
3.5
3.1
7.09
7.62
mmol/l
1.36
255
2375
13
81
1.61
0.81
1.1
1.0
—
—
—
0
0
11
66
1.67
0.79
1.0
1.1
—
—
—
0
0
47
376
1.26
0.78
1.1
1.2
0.18
1.23
u/ml
—
5
26
0
27
0.00
0.77
0.0
3.3
—
—
—
0
0
0
27
0.00
0.77
0.0
3.3
—
—
—
0
0
22
158
1.40
0.75
1.2
1.2
4.43
6.54
u/ml
—
7
63
21
150
1.41
0.73
3.0
3.1
0.82
0.84
nmol/l
0.04
12
120
7
41
1.71
0.70
2.6
2.6
42414.29
37751.34
ug/l
—
7
41
25
187
1.34
0.68
3.2
3.8
58.96
58.08
%
0.13
25
187
61
512
1.20
0.68
5.1
7.0
25.05
24.57
mmol/l
0.76
55
488
23
170
1.36
0.68
1.7
1.3
—
—
—
0
0
23
170
1.36
0.68
1.7
1.3
—
—
—
0
0
15
102
1.48
0.67
1.2
1.6
53.00
59.76
%
—
10
71
12
78
1.54
0.65
1.2
1.2
—
—
—
0
0
10
62
1.62
0.65
1.2
1.2
—
—
—
0
0
24
181
1.33
0.63
3.3
3.4
4.25
4.36
e9/l
0.11
24
181
37
298
1.25
0.61
3.1
2.1
95.46
92.32
%
0.38
37
289
8
51
1.57
0.60
1.3
1.5
—
290.00
—
0
5
33
264
1.26
0.58
1.6
1.5
—
—
—
0
0
19
140
1.36
0.58
1.7
2.1
2.71
4.85
umol/l
3.09
14
100
8
53
1.51
0.58
2.5
2.0
0.36
0.20
e9/l
—
8
48
39
320
1.23
0.56
1.4
1.4
—
—
—
0
0
17
124
1.38
0.56
1.4
1.5
—
—
—
0
0
30
239
1.26
0.55
1.3
1.3
—
—
—
0
0
31
384
0.80
0.55
1.4
1.7
2.25
4.57
mg/l
0.89
24
278
39
321
1.22
0.55
1.4
1.4
—
—
—
0
0
39
321
1.22
0.55
1.4
1.4
—
—
—
0
0
39
321
1.22
0.55
1.4
1.4
—
—
—
0
0
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
9
61
1.48
0.53
1.3
1.2
—
—
—
0
0
21
161
1.31
0.52
1.2
1.0
1.75
2.32
u/ml
0.14
11
82
12
83
1.45
0.52
1.8
1.7
—
—
—
0
0
27
216
1.26
0.49
1.3
1.4
4.09
14.59
e6/l
1.10
22
165
22
172
1.28
0.48
2.0
2.2
16.93
15.98
%
0.64
15
88
13
93
1.40
0.48
1.8
1.6
—
—
—
0
0
11
76
1.45
0.48
1.2
1.5
—
—
—
0
0
11
76
1.45
0.48
1.2
1.5
—
—
—
0
0
11
76
1.45
0.48
1.2
1.5
—
—
—
0
0
19
146
1.31
0.47
1.1
1.1
—
—
—
0
0
41
347
1.19
0.46
1.4
1.5
—
—
—
0
0
7
49
1.43
0.46
1.1
1.2
—
—
—
0
0
11
77
1.43
0.45
5.0
2.6
—
—
—
0
0
69
610
1.14
0.45
2.1
1.8
—
—
—
0
0
85
762
1.12
0.45
6.5
3.2
2.03
2.01
mmol/l
0.01
74
628
15
112
1.34
0.44
1.7
1.9
33.00
32.39
pg
0.15
15
112
284
2697
1.07
0.44
4.3
3.8
10.10
8.31
mg/mmol
0.22
169
1690
16
121
1.33
0.44
1.8
1.5
—
—
—
0
0
16
121
1.33
0.44
1.8
1.5
—
—
—
0
0
86
774
1.12
0.43
2.1
1.9
—
—
—
0
0
23
184
1.26
0.43
1.6
1.2
331.33
249.18
u/ml
0.47
12
112
149
1381
1.09
0.43
3.1
2.9
0.65
0.72
ug/l
0.94
111
877
37
313
1.19
0.42
1.8
1.5
1.09
1.18
g/l
1.47
37
295
16
122
1.32
0.42
1.8
1.5
—
—
—
0
0
8
57
1.41
0.42
2.5
2.0
472.88
413.57
e6/l
—
8
49
269
2556
1.07
0.41
3.7
3.2
547.68
354.78
mg/l
0.22
161
1630
0
16
0.00
0.41
0.0
1.8
—
1.24
—
0
16
16
123
1.31
0.40
1.8
1.5
—
—
—
0
0
5
34
1.47
0.40
1.0
1.2
—
—
—
0
0
5
34
1.47
0.40
1.8
1.7
—
—
—
0
0
16
124
1.29
0.38
1.8
1.5
—
—
—
0
0
16
124
1.29
0.38
1.8
1.5
—
—
—
0
0
19
151
1.26
0.38
1.1
1.1
—
—
—
0
0
5
36
1.39
0.38
2.0
2.3
—
—
—
0
0
9
69
1.31
0.37
1.7
1.6
—
—
—
0
0
18
222
0.81
0.34
1.6
1.5
—
—
—
0
0
10
73
1.37
0.34
1.3
1.0
279.60
291.53
mg/l
—
10
64
6
45
1.34
0.33
1.0
1.1
—
—
—
0
0
33
381
0.86
0.33
1.5
1.4
—
—
—
0
0
35
305
1.15
0.31
1.6
1.6
—
—
—
0
0
23
193
1.20
0.31
1.5
1.2
—
—
—
0
0
44
391
1.13
0.30
1.2
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
55
1.27
0.30
1.1
1.1
—
—
—
0
0
20
166
1.21
0.30
1.8
1.5
—
—
—
0
0
19
157
1.21
0.29
1.1
1.2
3.14
2.26
u/ml
—
7
47
5
72
0.69
0.26
1.6
1.5
—
—
—
0
0
78
723
1.08
0.26
3.9
3.5
1.23
1.23
mmol/l
0.07
68
624
9
74
1.22
0.25
1.9
1.2
—
—
—
0
0
9
75
1.20
0.25
1.9
1.2
—
—
—
0
0
9
77
1.17
0.24
1.0
1.5
—
—
—
0
0
33
368
0.89
0.22
3.4
3.5
45.22
48.98
%
0.35
33
360
5
41
1.22
0.22
1.0
1.1
1584.00
1667.51
miu/ml
—
5
41
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
12
98
1.23
0.21
1.2
1.5
—
—
—
0
0
12
98
1.23
0.21
1.2
1.5
—
—
—
0
0
17
145
1.18
0.20
1.1
1.1
114.65
116.80
%
0.11
17
135
0
14
0.00
0.20
0.0
2.4
—
0.93
—
0
14
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
24
268
0.89
0.17
2.1
1.6
—
—
—
0
0
8
69
1.16
0.16
1.6
1.1
—
—
—
0
0
6
79
0.76
0.15
1.8
2.4
—
—
—
0
0
13
114
1.14
0.12
1.1
1.1
94.62
96.02
%
0.07
13
106
14
157
0.89
0.11
1.0
1.1
8.20
100.74
iu/ml
—
5
38
23
248
0.93
0.09
1.4
1.3
—
—
—
0
0
28
299
0.93
0.09
1.6
1.5
—
—
—
0
0
11
124
0.89
0.09
1.2
1.1
—
—
—
0
0
6
54
1.11
0.09
3.5
1.8
—
—
—
0
0
49
512
0.96
0.09
13.4
9.3
1.12
1.33
%
1.77
49
507
5
60
0.83
0.08
1.0
1.4
—
—
—
0
0
5
65
0.77
0.08
1.0
1.1
—
—
—
0
0
8
75
1.07
0.07
1.3
1.5
—
—
—
0
0
8
75
1.07
0.07
1.3
1.2
—
—
—
0
0
8
75
1.07
0.07
1.3
1.2
—
—
—
0
0
8
76
1.05
0.07
1.3
1.2
—
—
—
0
0
8
76
1.05
0.07
1.3
1.2
—
—
—
0
0
8
76
1.05
0.07
1.3
1.2
—
—
—
0
0
12
109
1.10
0.06
2.3
2.3
—
—
—
0
0
16
171
0.93
0.05
2.4
3.0
6.67
7.49
mmol/l
1.19
16
166
22
210
1.05
0.03
1.7
2.3
6.78
71.62
ug/min
3.38
12
130
11
106
1.04
0.00
1.2
1.8
91.93
90.34
%
0.62
11
106
27
274
0.99
0.00
2.1
1.9
2.56
4.78
iu/l
2.08
13
102
14
138
1.01
0.00
1.2
1.1
—
—
—
0
0
18
182
0.99
0.00
2.3
2.9
1.28
1.49
mmol/l
0.83
18
176
60
601
1.00
0.00
1.5
1.5
—
—
—
0
0
37
373
0.99
0.00
2.5
1.8
—
—
—
0
0
10
95
1.05
0.00
1.1
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
-0.00
1.0
1.1
—
1.58
nmol/l
—
0
13
6
66
0.91
-0.00
1.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
51
510
1.00
-0.00
13.9
9.4
0.60
0.68
%
0.94
51
505
5
54
0.93
-0.00
1.6
2.1
—
—
—
0
0
5
54
0.93
-0.00
2.0
1.5
1.80
5.51
u/field
—
5
40
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_EUSTNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EUSTNAS | 1.042 [0.88, 1.23] | 0.633 |
| Birth year | 0.993 [0.98, 1.0] | 0.101 |
During the follow-up period (1.1.1998 — 31.12.2019), 209 out of 2905 females with H8_EUSTNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EUSTNAS | 1.333 [1.11, 1.6] | 0.002 |
| Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 270 out of 1926 males with H8_EUSTNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_EUSTNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.114% | 0.267% |
| 5 | 0.58% | 1.539% |
| 10 | 1.468% | 3.684% |
| 15 | 2.676% | 6.729% |
| 20 | 4.803% | 11.652% |
Relationships between endpoints
↥Index endpoint: H8_EUSTNAS – Other disorders of Eustachian tube
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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