auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1068 |
4. Check minimum number of eventsNone |
1068 |
5. Include endpointsNone |
1068 |
6. Filter based on genotype QC (FinnGen only) |
1068 |
Control definitions (FinnGen only)
- Control exclude
- H8_MIDDLEMASTOID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H65-H75
- Name in latin
- Aliae morbositates tubae auditivae
Similar endpoints
↥List of similar endpoints to
Other disorders of Eustachian tube
based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6062 | 3566 | 2467 |
| Only index persons | 5812 | 3458 | 2354 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.07 |
| Only index persons | 0.11 | 0.13 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 48.24 | 47.07 | 49.93 |
| Only index persons | 48.07 | 46.99 | 49.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1068 | 692 | 376 |
| Unadjusted period prevalence (%) | 0.21 | 0.24 | 0.17 |
| Median age at first event (years) | 55.08 | 51.57 | 61.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 938
- Matched controls
- 9379
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H69.0
ICD-10 Finland
Patulous Eustachian tube
2020.4
323.0
489
5
H69.8
ICD-10 Finland
Other specified disorders of Eustachian tube
1948.9
300.9
276
*
H69.9
ICD-10 Finland
Eustachian tube disorder, unspecified
335.2
191.7
188
7
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
255.5
131.6
132
6
UDC00
NOMESCO Finland
Ear microscopy
11.8
118.0
233
255
Z01.1
ICD-10 Finland
Examination of ears and hearing
7.3
111.0
307
588
DFF00
NOMESCO Finland
Pure tone audiometry
7.7
85.7
219
359
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
67.4
75.0
86
14
H65.3
ICD-10 Finland
Chronic mucoid otitis media
76.0
56.9
64
9
H66.0
ICD-10 Finland
Acute suppurative otitis media
8.4
54.8
127
172
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
151.5
54.5
57
*
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
45.0
51.4
63
15
H66.9
ICD-10 Finland
Otitis media, unspecified
8.5
49.6
113
148
UDH02
NOMESCO Finland
Rhinopharyngoscopy
6.2
49.3
143
266
H65.2
ICD-10 Finland
Chronic serous otitis media
126.3
45.2
48
*
H92.0
ICD-10 Finland
Otalgia
6.6
41.3
112
189
R01AD09
ATC
mometasone; nasal
2.6
41.2
525
3112
DGW00
NOMESCO Finland
Dilatation of eustachian tube
+∞
33.5
32
*
R01AD08
ATC
fluticasone; nasal
2.5
33.0
341
1742
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
31.4
30
*
R01AD12
ATC
fluticasone furoate; nasal
2.4
31.2
355
1892
H29
ICPC
Ear symptom/complaint other
3.7
30.7
146
444
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
29.3
28
*
DC1AD
NOMESCO Finland
Temporalbone CT
26.3
27.7
38
15
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.9
25.6
175
687
H01
ICPC
Ear pain/earache
3.3
25.4
142
487
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
2.4
24.7
249
1220
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
23.0
22
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
4.3
21.6
84
212
H93.1
ICD-10 Finland
Tinnitus
3.7
21.4
97
281
4122
FHL
Tympanostomy (tympanic tube)
51.3
21.2
25
5
H02
ICPC
Hearing complaint
2.9
19.9
129
484
DCD00
NOMESCO Finland
Myringoplasty
+∞
19.9
19
*
SPAT1043
SPAT
Audiometry
3.0
19.5
120
436
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
32.0
19.3
25
8
H13
ICPC
Plugged feeling ear
2.4
18.5
183
873
TDA90
NOMESCO Finland
Removal wax from ear
14.0
17.8
30
22
J31.0
ICD-10 Finland
Chronic rhinitis
3.2
17.8
99
334
H02AB06
ATC
prednisolone; systemic
1.8
17.6
440
3042
DFF15
NOMESCO Finland
Speech audiometry
4.6
17.2
60
136
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
51.0
17.0
20
*
N07CA01
ATC
betahistine; oral
3.2
16.9
94
317
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
23.5
16.5
23
10
J01FA10
ATC
azithromycin; systemic
1.8
16.0
560
4262
H60.9
ICD-10 Finland
Otitis externa, unspecified
3.3
15.7
80
255
H65.0
ICD-10 Finland
Acute serous otitis media
11.0
15.6
29
27
UDM02
NOMESCO Finland
Sinoscopy
6.3
15.4
41
68
R01BA52
ATC
pseudoephedrine, combinations; oral
1.9
15.0
302
1910
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
14.9
476
3494
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
14.6
215
1214
A02BC05
ATC
esomeprazole; systemic
1.8
14.5
380
2614
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.9
14.5
266
1628
ZZG00
NOMESCO Finland
Graft of cartilage
152.3
14.5
15
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.8
14.1
93
352
H91.9
ICD-10 Finland
Hearing loss, unspecified
4.1
14.0
55
141
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.6
14.0
48
108
J01CA04
ATC
amoxicillin; systemic
1.9
13.7
755
6457
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
76.3
13.6
15
*
R03AC02
ATC
salbutamol; inhalant
1.7
13.6
484
3628
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
13.6
13
*
J01DB01
ATC
cefalexin; oral
1.9
13.4
757
6492
H60.3
ICD-10 Finland
Other infective otitis externa
5.9
13.4
37
65
N03AX16
ATC
pregabalin; oral
1.9
13.4
226
1336
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
4.1
13.2
51
129
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
40.7
13.2
16
*
R51.80
ICD-10 Finland
Headache
2.1
13.1
156
802
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
8.5
13.1
28
34
M03BX02
ATC
tizanidine; oral
1.7
13.1
566
4462
R42
ICD-10 Finland
Dizziness and giddiness
1.9
12.9
201
1152
A02BC02
ATC
pantoprazole; systemic
1.7
12.6
581
4635
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.1
12.6
49
125
J01AA02
ATC
doxycycline; systemic
1.8
12.6
710
6003
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
12.5
12
*
DGB00
NOMESCO Finland
Obliteration of eustachian tube
+∞
12.5
12
*
H60.8
ICD-10 Finland
Other otitis externa
4.9
12.5
40
84
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
12.3
260
1656
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
+∞
11.5
11
*
DGW99
NOMESCO Finland
Other operation on eustachian tube
+∞
11.5
11
*
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
11.5
11
*
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
121.4
11.4
12
*
H69
ICD-10 Finland
Other disorders of Eustachian tube
121.4
11.4
12
*
A02BC03
ATC
lansoprazole; oral
1.7
11.1
267
1758
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
11.1
329
2304
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
10.9
212
1304
R13
ICD-10 Finland
Dysphagia
2.7
10.8
72
276
J01DA01
ATC
[U] cefalexin; systemic
1.6
10.6
564
4570
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.6
10.3
45
128
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
9.8
366
2700
EMB10
NOMESCO Finland
Tonsillectomy
2.7
9.8
66
256
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
9.7
404
3056
N06AX11
ATC
mirtazapine; oral
1.6
9.7
274
1880
UKC02
NOMESCO Finland
Cystoscopy
2.0
9.6
133
724
M25.5
ICD-10 Finland
Pain in joint
1.7
9.5
252
1699
J02AC01
ATC
fluconazole; systemic
1.6
9.4
374
2790
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
9.4
9
*
R06AX27
ATC
desloratadine; oral
1.7
9.4
251
1693
J35.0
ICD-10 Finland
Chronic tonsillitis
2.7
9.3
62
237
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
9.3
152
879
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
4.4
9.3
32
74
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
9.2
353
2607
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
9.1
355
2635
N02BE01
ATC
paracetamol; systemic, rectal
1.7
9.1
768
6838
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
37.1
9.0
11
*
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
8.9
149
870
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
8.8
206
1336
N03AX12
ATC
gabapentin; oral
1.9
8.7
144
835
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
8.6
233
1571
DAX08
NOMESCO Finland
Fitting of hearing aid
3.5
8.6
39
116
H04
ICPC
Ear discharge
3.6
8.4
36
102
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
8.4
177
1109
H60
ICD-10 Finland
Otitis externa
2.9
8.4
49
174
R06AE07
ATC
cetirizine; oral
1.5
8.4
391
3005
G44.2
ICD-10 Finland
Tension-type headache
1.9
8.4
133
762
R06.0
ICD-10 Finland
Dyspnoea
1.7
8.3
209
1378
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
8.3
73
327
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
8.3
8
*
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
8.3
8
*
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
+∞
8.3
8
*
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
8.3
8
*
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
8.3
8
*
WX110
NOMESCO Finland
Local anesthesy
1.5
8.3
617
5241
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
8.6
8.3
17
20
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.1
8.3
96
487
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
8.2
90
445
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
5.7
8.2
22
39
H66
ICD-10 Finland
Suppurative and unspecified otitis media
4.2
8.1
29
70
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.7
8.1
53
203
R01AD11
ATC
triamcinolone; nasal
2.1
8.1
87
426
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
6.4
8.0
20
32
M31.3
ICD-10 Finland
Wegener granulomatosis
22.2
8.0
11
5
ZXA05
NOMESCO Finland
Left side
1.6
8.0
208
1386
J30.0
ICD-10 Finland
Vasomotor rhinitis
3.7
7.9
33
92
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.0
7.9
105
565
H27
ICPC
Fear of ear disease
5.8
7.9
21
37
K07.60
ICD-10 Finland
Snapping jaw
2.8
7.8
50
188
N02AX02
ATC
tramadol; systemic, rectal
1.5
7.8
348
2638
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
7.8
149
906
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
7.7
206
1377
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
7.7
312
2312
M79.1
ICD-10 Finland
Myalgia
1.9
7.6
116
656
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
7.6
207
1394
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
7.5
383
2979
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
7.5
92
479
M79.6
ICD-10 Finland
Pain in limb
1.5
7.5
311
2317
H91.8
ICD-10 Finland
Other specified hearing loss
6.5
7.4
18
28
DCD10
NOMESCO Finland
Tympanoplasty
80.7
7.4
8
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
7.4
152
944
L08
ICPC
Shoulder symptom/complaint
1.7
7.3
161
1020
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
7.3
7
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.0
7.3
40
138
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.1
7.3
86
440
SPAT1044
SPAT
Tympanometry
3.9
7.2
28
74
R06AX13
ATC
loratadine; oral
1.7
7.2
141
862
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.1
7.2
81
405
N17
ICPC
Vertigo/dizziness
1.9
7.2
98
532
ZXA00
NOMESCO Finland
Right side
1.6
7.2
213
1462
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
7.2
128
762
R09
ICPC
Sinus symptom/complaint
2.1
7.1
77
381
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.0
7.1
87
452
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.1
7.1
74
361
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
7.0
84
431
DHB50
NOMESCO Finland
Turbinoplasty
3.4
7.0
31
92
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.7
7.0
150
944
A02BC01
ATC
omeprazole; systemic
1.6
6.9
222
1553
J01DA06
ATC
[U] cefuroxime; systemic
1.8
6.9
125
746
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.1
6.9
36
121
H61.2
ICD-10 Finland
Impacted cerumen
2.4
6.8
54
230
J34.2
ICD-10 Finland
Deviated nasal septum
2.5
6.8
52
219
SPAT1041
SPAT
Comprehensive hearing test
5.7
6.8
18
32
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.0
6.8
37
128
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
4.0
6.7
25
64
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
2.0
6.7
88
472
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.6
322
2466
WX725
NOMESCO Finland
Noninvasive ventilation
2.6
6.6
46
181
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
3.4
6.6
29
86
A02BA02
ATC
ranitidine; systemic
1.6
6.5
161
1051
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
6.5
192
1314
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.5
314
2398
G04CA02
ATC
tamsulosin; oral
1.7
6.5
144
916
J01FA06
ATC
roxithromycin; oral
1.4
6.4
338
2626
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
6.4
97
545
H02AB04
ATC
methylprednisolone; systemic
1.7
6.4
126
772
R05
ICD-10 Finland
Cough
1.6
6.4
170
1133
Z71.8
ICD-10 Finland
Other specified counselling
1.6
6.4
207
1448
R03DC03
ATC
montelukast; oral
1.7
6.3
138
871
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.2
6.3
59
273
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
6.3
341
2662
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.8
6.3
100
574
3818X
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Other disorders of Eustachian tube
+∞
6.3
6
*
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
6.3
6
*
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
6.3
6
*
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
6.3
6
*
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
+∞
6.3
6
*
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
26.9
6.2
8
*
4451
FHL
Guitar cutting
3.7
6.2
25
69
R01AD01
ATC
beclometasone; nasal
1.7
6.1
133
839
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.8
6.1
37
137
D07AC01
ATC
betamethasone; topical
1.5
6.1
277
2081
R06.5
ICD-10 Finland
Mouth breathing
2.0
6.1
74
385
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
2.4
6.1
49
211
R51
ICD-10 Finland
Headache
2.5
6.1
46
192
N05CF01
ATC
zopiclone; oral
1.5
6.0
254
1883
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
10.1
6.0
11
11
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
6.0
118
723
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
788
6499
1.81
15.87
5.3
4.0
10.7
11.6
mm/h
0.98
749
6011
548
4138
1.67
14.78
7.5
6.3
1.2
1.2
mmol/l
0.41
473
3503
480
3633
1.58
11.92
2.5
2.2
78.1
76.5
nmol/l
0.67
442
3271
376
2695
1.61
11.70
2.7
2.4
58.1
56.1
u/l
0.41
353
2487
236
1503
1.73
11.58
1.3
1.3
14.1
9.7
u/ml
0.39
83
594
972
8844
2.10
11.14
17.7
12.8
19.1
22.6
mg/l
3.35
782
6939
241
1575
1.68
10.66
1.4
1.3
18.0
32.3
iu/ml
3.32
78
499
804
6963
1.63
10.40
4.7
4.1
14.7
14.7
pmol/l
0.00
748
6371
484
3760
1.53
10.17
6.7
5.6
1.2
1.2
mmol/l
0.45
445
3420
462
3556
1.53
10.12
5.4
4.6
35.9
35.8
g/l
0.12
427
3317
236
1555
1.66
10.06
4.1
3.7
121.9
366.3
ng/l
2.35
172
1161
774
6663
1.59
10.06
9.3
7.2
76.3
77.3
u/l
0.28
745
6256
346
2517
1.55
9.73
2.2
2.1
116.6
244.4
u/l
2.75
318
2377
114
610
1.97
9.70
2.3
2.4
20.4
18.7
au/ml
—
8
42
615
5057
1.51
9.67
10.3
8.8
3.9
4.1
e9/l
0.52
567
4451
605
4999
1.48
8.99
5.5
4.4
6.6
6.6
mmol/l
0.43
562
4646
412
3156
1.50
8.92
3.5
3.4
37.5
51.1
ng/l
0.33
257
2085
912
8253
1.72
8.89
5.7
4.8
2.9
1.9
mu/l
0.52
857
7603
549
4458
1.48
8.86
7.0
6.0
10.9
11.2
umol/l
0.42
532
4237
58
249
2.41
8.58
1.5
1.4
292.4
293.5
ug/g
0.01
38
144
978
9073
1.92
8.24
19.5
14.5
4.0
4.0
mmol/l
0.08
961
8817
976
9050
1.91
8.21
19.2
14.4
139.7
139.7
mmol/l
0.14
961
8815
102
559
1.91
8.09
1.7
1.6
—
—
—
0
0
134
801
1.77
8.05
2.9
2.1
350.9
373.2
nmol/l
0.79
119
738
1006
9450
2.11
7.76
12.8
9.9
26.0
26.0
u/l
0.03
988
9135
427
3396
1.43
7.20
2.1
1.9
96.8
95.3
pmol/l
0.29
230
1727
209
1453
1.55
6.90
1.8
1.7
1166.4
1212.0
nmol/l
0.33
160
1090
282
2106
1.46
6.55
1.3
1.3
0.9
1.8
u/ml
1.84
73
566
519
4349
1.38
6.13
4.4
3.5
0.0
0.0
estimate
0.00
91
833
526
4429
1.37
5.97
4.4
3.5
0.0
0.0
estimate
0.80
87
814
683
5998
1.38
5.95
3.6
3.0
43.5
45.2
u/l
0.25
646
5631
520
4383
1.36
5.80
5.9
4.8
0.0
0.0
estimate
0.50
90
841
185
1299
1.51
5.78
2.0
1.8
—
—
—
0
0
18
50
3.64
5.77
1.3
1.2
—
—
—
0
0
99
600
1.72
5.67
3.0
2.9
148.0
169.6
ng/l
0.21
94
547
254
1910
1.43
5.59
4.2
3.9
1.0
1.0
kg/l
0.03
44
257
283
2170
1.41
5.58
2.9
2.5
3516.7
6052.7
umol/l
0.60
250
1892
69
380
1.87
5.44
2.0
2.0
38.3
39.3
u/l
0.21
63
345
1034
9943
2.25
5.40
25.4
19.0
251.8
253.9
e9/l
0.54
1020
9708
477
4002
1.35
5.33
3.4
2.7
101.1
111.3
ug/l
0.76
449
3707
49
241
2.08
5.33
2.0
2.1
10.5
11.8
mg/l
0.65
43
223
1034
9950
2.23
5.27
25.4
19.0
4.5
4.5
e12/l
1.37
1016
9692
1034
9955
2.21
5.18
25.4
19.1
135.0
135.3
g/l
0.31
1026
9811
49
245
2.05
5.11
2.9
2.8
—
—
—
0
0
360
2911
1.36
5.06
4.2
3.1
32.2
31.5
u/l
0.08
344
2768
138
954
1.51
4.62
3.4
2.5
6.5
8.8
umol/l
1.42
118
825
103
670
1.59
4.52
7.9
7.3
8.8
9.3
mmol/l
0.31
98
637
271
2134
1.36
4.43
2.8
2.1
2.6
3.0
mg/l
2.51
240
1811
17
55
3.12
4.37
1.4
1.7
—
—
—
0
0
136
950
1.49
4.34
20.5
22.3
1.5
1.2
inr
0.88
16
134
45
235
1.96
4.21
1.1
1.1
—
—
—
0
0
67
397
1.73
4.21
10.5
10.0
24.2
24.4
mmol/l
0.16
67
372
91
590
1.59
4.06
1.3
1.2
367.2
191.0
u/ml
0.39
84
545
35
169
2.11
4.05
2.1
2.1
135.3
128.8
g/l
0.95
23
128
126
879
1.49
4.05
7.6
7.5
0.9
1.2
mmol/l
0.43
100
695
861
8034
1.37
3.98
5.8
5.4
39.5
39.4
mmol/mol
0.05
808
7481
27
118
2.32
3.97
1.2
1.3
—
—
—
0
0
161
1183
1.43
3.95
2.9
2.3
2.4
2.4
g/l
0.71
143
1094
47
255
1.88
3.95
1.1
1.1
4.4
4.2
u/ml
—
8
34
15
48
3.16
3.94
1.1
1.0
—
—
—
0
0
151
1098
1.44
3.92
3.0
2.4
21.9
23.2
%
0.54
115
934
126
885
1.48
3.92
8.1
7.5
5.1
5.1
kpa
0.07
118
849
126
885
1.48
3.92
8.1
7.5
13.4
12.3
kpa
1.50
119
851
11
29
3.82
3.81
1.1
1.1
—
—
—
0
0
908
8568
1.40
3.74
4.7
4.4
5.8
5.9
mmol/l
1.96
855
7852
55
320
1.76
3.71
4.3
4.8
1.7
1.6
%
0.25
49
303
925
8761
1.42
3.68
4.8
4.3
4.7
4.7
mmol/l
0.24
871
8181
938
8907
1.44
3.67
5.2
4.7
2.8
2.8
mmol/l
0.01
876
8273
76
486
1.61
3.62
1.1
1.0
—
—
—
0
0
659
5971
1.27
3.51
3.5
3.1
—
—
—
0
0
18
69
2.64
3.48
1.2
1.1
18.0
81.8
u/ml
—
5
6
245
1968
1.32
3.42
1.9
1.7
0.8
1.1
mg/l
1.53
184
1489
919
8718
1.39
3.41
4.7
4.2
1.5
1.5
mmol/l
0.30
860
8097
142
1050
1.41
3.37
4.4
4.2
33.7
32.1
%
1.14
112
712
44
247
1.81
3.36
1.3
1.3
—
—
—
0
0
142
1051
1.40
3.35
7.7
5.2
1.0
1.0
mmol/l
0.21
135
972
166
1262
1.37
3.34
2.6
2.0
30.7
29.6
s
0.66
159
1227
30
148
2.06
3.33
1.4
1.5
—
—
—
0
0
95
652
1.50
3.33
3.9
3.5
73.1
80.8
ng/l
0.71
82
584
173
1328
1.36
3.28
4.4
3.0
0.8
0.8
mmol/l
0.04
163
1242
35
184
1.93
3.27
1.1
1.2
2.4
6.2
u/ml
—
5
15
51
302
1.72
3.27
2.0
1.7
—
—
—
0
0
343
2897
1.27
3.24
3.0
3.4
2.3
2.4
mmol/l
0.65
308
2558
72
468
1.58
3.23
3.2
3.3
1.1
1.7
mmol/l
0.99
60
362
221
1768
1.32
3.16
1.7
1.5
—
—
—
0
0
52
316
1.68
3.05
1.9
1.8
—
—
—
0
0
393
3404
1.24
2.93
4.7
3.7
—
—
—
0
0
123
911
1.40
2.90
1.9
1.7
—
—
—
0
0
886
8409
1.31
2.86
4.2
3.8
1.3
1.3
mmol/l
0.55
827
7772
122
906
1.39
2.84
2.0
1.7
—
—
—
0
0
30
159
1.91
2.78
4.2
5.8
234.0
336.0
iu/ml
—
7
24
207
1670
1.30
2.77
1.6
1.4
—
—
—
0
0
353
3038
1.24
2.76
4.0
3.0
—
—
—
0
0
271
2266
1.26
2.73
2.8
2.9
961.1
1103.4
ng/l
0.40
241
1914
91
649
1.44
2.67
2.0
2.7
66.1
66.8
g/l
0.29
83
599
47
290
1.65
2.64
1.9
1.7
—
—
—
0
0
33
184
1.82
2.63
1.3
1.7
—
—
—
0
0
29
155
1.90
2.63
1.4
1.4
19.0
25.6
u/l
0.66
21
130
215
1757
1.28
2.60
3.1
2.4
6.7
6.5
e6/l
0.02
200
1562
165
1302
1.32
2.60
2.9
2.3
13.5
13.4
umol/l
0.09
148
1194
236
1952
1.27
2.59
1.6
1.5
21.7
20.8
nmol/l
0.46
212
1656
878
8356
1.29
2.54
15.7
11.8
83.2
83.5
ml/min/173m2
0.13
751
6842
466
4171
1.21
2.41
4.1
3.8
—
—
—
0
0
260
2193
1.25
2.40
5.3
4.7
2.3
2.8
ug/l
0.52
239
1972
47
300
1.59
2.34
3.5
3.8
24.6
24.9
mmol/l
0.41
47
287
23
119
1.95
2.31
1.2
1.1
—
—
—
0
0
272
2315
1.23
2.31
3.8
2.9
0.3
0.4
e6/l
0.98
212
1741
246
2071
1.24
2.31
2.7
2.1
—
—
—
0
0
50
326
1.56
2.28
1.7
2.1
1.4
1.5
g/l
0.30
40
287
78
558
1.43
2.28
2.8
2.1
13.2
12.9
nmol/l
0.10
68
496
83
604
1.41
2.21
2.6
3.4
4.4
4.6
pmol/l
0.69
73
532
65
452
1.47
2.21
1.9
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
38
235
1.64
2.16
3.8
2.8
0.3
0.4
u/ml
1.16
22
130
9
30
3.02
2.15
6.2
4.7
—
—
—
0
0
10
37
2.72
2.10
1.1
1.5
—
—
—
0
0
10
37
2.72
2.10
1.1
1.5
—
—
—
0
0
862
8238
1.24
2.07
19.4
13.7
39.6
39.9
%
0.43
614
6072
21
110
1.93
2.06
1.3
1.4
—
—
—
0
0
26
147
1.79
2.04
1.2
1.4
—
—
—
0
0
160
1301
1.27
2.02
3.5
2.7
2.7
2.6
e6/l
0.06
96
681
21
111
1.91
2.02
1.1
1.4
—
—
—
0
0
42
274
1.55
1.95
1.7
1.6
0.0
0.1
iu/ml
—
8
50
22
121
1.84
1.89
1.4
1.3
8.3
7.1
mmol/l
0.65
12
81
28
166
1.71
1.89
1.3
1.4
—
—
—
0
0
95
728
1.33
1.88
9.6
8.2
122.5
121.0
g/l
0.31
88
705
16
79
2.04
1.86
2.7
3.0
65.3
55.5
%
0.81
11
55
169
1398
1.25
1.86
3.1
2.5
0.9
1.1
e6/l
0.54
105
776
106
831
1.31
1.79
4.2
4.4
6.3
26.1
ug/l
1.23
84
685
271
2362
1.20
1.78
1.7
1.6
1.3
1.4
mmol/l
0.15
228
1990
37
240
1.56
1.78
1.2
1.2
4.9
2.5
u/ml
—
8
25
26
154
1.71
1.77
1.1
1.1
—
10.6
—
0
12
15
284
0.52
1.76
3.2
3.8
1.2
1.3
mmol/l
0.22
15
276
6
18
3.35
1.75
1.0
1.2
—
—
—
0
0
22
125
1.78
1.73
2.3
3.2
0.7
1.6
%
0.94
15
102
8
30
2.68
1.72
1.6
1.4
—
—
—
0
0
0
48
0.00
1.70
0.0
2.9
—
—
—
0
0
37
243
1.54
1.70
1.2
1.2
10.3
10.1
u/ml
—
10
39
101
795
1.30
1.67
3.0
2.3
32.8
35.1
u/l
0.29
85
663
34
220
1.56
1.67
2.3
1.6
36.0
41.8
nmol/l
0.36
34
210
7
25
2.81
1.65
1.1
1.0
—
—
—
0
0
41
280
1.48
1.59
1.5
2.2
10.1
10.6
g/l
0.22
32
242
30
191
1.59
1.58
2.5
2.5
8.6
8.0
kpa
1.40
30
179
7
26
2.70
1.58
1.4
1.8
46.0
54.2
ug/l
—
7
26
51
364
1.42
1.58
2.1
1.5
363.2
288.8
mu/l
0.76
46
327
22
129
1.72
1.57
1.1
1.4
—
—
—
0
0
31
200
1.57
1.55
1.5
1.6
2523.5
14787.5
e6/l
3.15
19
150
57
417
1.39
1.54
2.2
2.2
6228.0
3429.5
u/l
0.31
13
176
25
153
1.65
1.54
1.6
1.5
—
—
—
0
0
10
44
2.28
1.53
1.4
1.2
10.0
11.3
u/l
—
10
39
30
193
1.57
1.52
1.3
1.5
—
—
—
0
0
17
93
1.84
1.52
1.5
1.4
8.1
12.6
mmol/l
—
6
21
204
1759
1.20
1.51
4.8
4.2
21.3
21.0
%
0.10
103
795
9
37
2.44
1.48
1.4
2.2
—
—
—
0
0
17
94
1.82
1.48
1.1
1.1
60.3
52.0
u/l
—
10
69
15
80
1.89
1.45
4.1
3.5
—
—
—
0
0
29
188
1.56
1.44
1.3
1.6
—
—
—
0
0
6
22
2.74
1.43
1.0
1.2
—
—
—
0
0
22
133
1.67
1.43
1.1
1.0
5.7
1.5
u/ml
0.44
11
62
23
141
1.65
1.42
1.3
1.6
—
—
—
0
0
20
118
1.71
1.42
1.4
1.1
—
—
—
0
0
9
40
2.26
1.40
1.0
1.3
—
—
—
0
0
9
40
2.26
1.40
1.0
1.3
—
—
—
0
0
10
46
2.19
1.40
1.0
1.3
—
—
—
0
0
10
46
2.19
1.40
1.0
1.3
—
—
—
0
0
25
158
1.60
1.38
2.5
1.7
166.6
207.6
pmol/l
1.51
25
149
9
41
2.21
1.37
1.0
1.2
—
83.0
%
—
0
7
5
17
2.95
1.36
1.0
1.1
101.4
99.2
%
—
5
17
5
17
2.95
1.36
1.0
1.1
—
—
—
0
0
179
1542
1.19
1.34
3.0
2.9
2.4
2.4
mmol/l
1.04
156
1361
9
42
2.15
1.34
1.2
1.6
—
—
—
0
0
9
42
2.15
1.34
1.2
1.6
—
—
—
0
0
9
42
2.15
1.34
1.2
1.6
—
—
—
0
0
9
42
2.15
1.34
1.2
1.6
—
—
—
0
0
11
54
2.05
1.33
1.3
1.4
—
—
—
0
0
95
767
1.26
1.33
3.4
2.2
0.2
0.2
g/l
0.96
89
725
82
1024
0.78
1.32
5.2
6.8
—
—
—
0
0
785
7537
1.16
1.32
21.3
15.7
13.6
13.6
%
0.12
774
7386
22
137
1.62
1.30
1.2
1.1
—
—
—
0
0
14
242
0.57
1.27
3.3
3.9
3.9
3.9
mmol/l
0.09
14
221
32
219
1.48
1.27
1.2
1.2
—
—
—
0
0
37
262
1.43
1.24
1.5
1.3
—
—
—
0
0
203
1782
1.17
1.23
1.7
1.7
60947195.4
33756258.1
pmol/l
0.18
169
1499
64
498
1.30
1.21
1.4
1.4
—
—
—
0
0
43
315
1.38
1.20
1.5
1.3
229.5
246.6
miu/ml
0.12
24
157
40
290
1.39
1.19
1.8
1.7
—
—
—
0
0
263
2366
1.15
1.15
5.4
3.9
0.0
0.0
estimate
0.88
86
823
20
126
1.60
1.15
3.8
2.5
7.3
36.2
u/ml
0.44
20
119
15
88
1.71
1.11
1.5
1.6
—
—
—
0
0
15
88
1.71
1.11
1.1
1.1
—
—
—
0
0
41
303
1.37
1.10
1.5
2.2
—
—
—
0
0
41
303
1.37
1.10
1.5
2.2
3.5
3.8
g/l
0.74
28
224
41
303
1.37
1.10
1.5
2.2
7.3
7.4
g/l
0.17
29
235
7
31
2.27
1.10
1.3
1.8
—
—
—
0
0
7
31
2.27
1.10
1.3
1.8
—
—
—
0
0
85
695
1.24
1.10
1.2
1.2
115.8
145.3
iu/ml
0.37
44
274
37
269
1.39
1.10
1.1
1.1
—
—
—
0
0
7
32
2.20
1.08
1.3
1.8
—
—
—
0
0
80
653
1.24
1.06
1.8
2.4
6.1
6.8
ug/l
0.16
70
586
67
828
0.80
1.03
1.6
1.7
—
—
—
0
0
14
83
1.70
1.01
1.0
1.1
—
—
—
0
0
21
139
1.52
1.00
1.1
1.2
—
—
—
0
0
13
76
1.72
0.99
1.1
1.0
—
—
—
0
0
16
100
1.61
0.97
1.3
1.1
—
—
—
0
0
25
174
1.45
0.95
1.3
1.1
8.9
2.0
u/ml
0.45
12
70
38
286
1.34
0.94
1.5
2.2
3.2
3.2
g/l
0.01
29
226
15
93
1.62
0.94
1.1
1.1
—
—
—
0
0
36
270
1.34
0.91
1.1
1.1
—
—
—
0
0
23
159
1.46
0.91
1.7
1.3
—
—
—
0
0
23
159
1.46
0.91
1.7
1.3
—
—
—
0
0
6
28
2.15
0.91
3.0
1.8
—
—
—
0
0
25
176
1.43
0.91
3.2
3.6
59.0
57.9
%
0.16
25
176
138
1211
1.16
0.87
2.4
2.1
—
—
—
0
0
8
43
1.87
0.87
1.4
1.4
—
—
—
0
0
8
43
1.87
0.87
1.4
1.4
—
—
—
0
0
11
64
1.73
0.86
2.5
2.0
738.3
762.3
e6/l
—
6
27
24
170
1.42
0.85
3.2
3.3
4.3
4.3
e9/l
0.05
24
170
21
145
1.46
0.85
3.0
3.1
0.8
0.8
nmol/l
0.03
12
117
79
663
1.21
0.84
1.8
2.5
75.5
69.1
ml/min/173m2
0.85
37
279
0
26
0.00
0.78
0.0
3.4
—
—
—
0
0
0
26
0.00
0.78
0.0
3.4
—
—
—
0
0
32
244
1.32
0.76
1.6
2.1
36.8
37.8
g/l
0.36
26
216
10
59
1.70
0.76
1.0
1.1
—
—
—
0
0
44
351
1.26
0.75
1.6
1.4
—
—
—
0
0
59
487
1.22
0.75
5.2
7.0
25.1
24.5
mmol/l
0.85
52
455
26
192
1.36
0.75
1.5
1.4
—
—
—
0
0
125
1103
1.15
0.75
2.2
2.0
—
—
—
0
0
9
55
1.64
0.73
1.2
1.2
—
—
—
0
0
126
1115
1.15
0.73
1.7
1.8
1.4
1.4
%
0.10
107
994
62
517
1.21
0.72
1.4
1.3
—
—
—
0
0
17
117
1.46
0.72
1.4
1.4
—
—
—
0
0
34
265
1.29
0.70
1.8
2.4
0.9
0.9
g/l
0.02
27
237
27
353
0.76
0.70
1.4
1.7
2.4
4.5
mg/l
0.69
22
250
19
136
1.40
0.67
1.1
1.1
—
—
—
0
0
283
2642
1.10
0.66
3.5
3.1
7.0
7.6
mmol/l
1.53
238
2231
7
44
1.59
0.65
1.1
1.2
—
—
—
0
0
21
155
1.36
0.63
1.2
1.2
4.5
6.6
u/ml
—
6
62
8
50
1.60
0.61
2.5
2.0
0.4
0.2
e9/l
—
8
45
31
245
1.27
0.60
1.6
1.5
—
—
—
0
0
96
849
1.14
0.59
3.0
3.1
—
—
—
0
0
8
54
1.49
0.57
2.5
2.0
472.9
413.7
e6/l
—
8
46
12
81
1.49
0.57
1.8
1.7
—
—
—
0
0
14
98
1.43
0.56
1.2
1.6
50.2
59.3
%
—
9
68
8
55
1.46
0.56
1.3
1.2
—
—
—
0
0
6
37
1.63
0.55
1.0
1.1
—
—
—
0
0
13
90
1.45
0.55
1.8
1.6
—
—
—
0
0
22
168
1.32
0.55
1.5
1.2
331.3
245.8
u/ml
0.49
12
101
26
204
1.28
0.54
1.3
1.4
4.2
15.4
e6/l
1.10
21
155
11
74
1.49
0.53
1.2
1.5
—
—
—
0
0
11
74
1.49
0.53
1.2
1.5
—
—
—
0
0
11
74
1.49
0.53
1.2
1.5
—
—
—
0
0
9
65
1.39
0.50
1.7
1.5
—
—
—
0
0
63
549
1.16
0.49
2.2
1.8
—
—
—
0
0
78
694
1.13
0.46
2.2
1.9
—
—
—
0
0
7
49
1.43
0.46
1.3
1.4
—
290.0
—
0
5
28
228
1.23
0.45
1.4
1.3
—
—
—
0
0
21
165
1.28
0.45
1.9
2.2
17.1
16.0
%
0.73
14
86
5
31
1.62
0.43
2.0
2.3
—
—
—
0
0
5
32
1.57
0.42
1.0
1.2
—
—
—
0
0
22
176
1.26
0.42
1.5
1.2
—
—
—
0
0
10
70
1.43
0.41
5.3
2.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
1.2
—
0
15
29
347
0.83
0.41
1.6
1.5
—
—
—
0
0
34
288
1.19
0.39
1.8
1.5
1.1
1.2
g/l
1.29
34
271
14
107
1.31
0.37
1.6
1.8
33.2
32.4
pg
0.20
14
107
9
69
1.31
0.37
1.3
1.0
286.2
288.9
mg/l
—
9
61
19
152
1.25
0.37
1.8
1.4
—
—
—
0
0
138
1286
1.08
0.37
3.1
2.9
0.6
0.7
ug/l
1.03
101
813
33
281
1.18
0.37
1.4
1.4
—
—
—
0
0
33
281
1.18
0.37
1.4
1.4
—
—
—
0
0
267
2550
1.06
0.36
4.6
4.0
10.6
8.6
mg/mmol
0.23
160
1598
11
81
1.36
0.36
2.3
1.7
7.7
7.4
mmol/l
—
5
52
33
282
1.18
0.35
1.4
1.4
—
—
—
0
0
33
282
1.18
0.35
1.4
1.4
—
—
—
0
0
6
44
1.37
0.34
1.0
1.1
—
—
—
0
0
35
302
1.16
0.34
1.4
1.5
—
—
—
0
0
80
730
1.10
0.34
6.6
3.2
2.0
2.1
mmol/l
0.06
68
578
75
682
1.11
0.34
3.9
3.4
1.2
1.2
mmol/l
0.07
65
590
15
188
0.79
0.33
1.6
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
54
1.30
0.30
1.1
1.1
—
—
—
0
0
19
226
0.84
0.27
2.6
1.7
—
—
—
0
0
8
65
1.23
0.27
2.0
1.2
—
—
—
0
0
8
65
1.23
0.27
1.6
1.1
—
—
—
0
0
8
66
1.21
0.26
2.0
1.2
—
—
—
0
0
9
72
1.25
0.25
1.0
1.5
—
—
—
0
0
39
350
1.12
0.24
1.3
1.4
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
1584.0
1731.3
miu/ml
—
5
38
22
253
0.87
0.23
1.6
1.5
—
—
—
0
0
17
144
1.18
0.22
1.1
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.4
—
0.9
—
0
14
6
48
1.25
0.20
3.5
1.9
—
—
—
0
0
32
353
0.90
0.19
3.4
3.4
44.2
48.8
%
0.46
32
346
8
69
1.16
0.16
1.3
1.1
—
—
—
0
0
8
69
1.16
0.16
1.3
1.1
—
—
—
0
0
8
70
1.14
0.16
1.3
1.1
—
—
—
0
0
8
70
1.14
0.16
1.3
1.1
—
—
—
0
0
8
70
1.14
0.16
1.3
1.1
—
—
—
0
0
8
70
1.14
0.16
1.4
1.5
—
—
—
0
0
13
111
1.17
0.15
1.8
1.4
—
—
—
0
0
13
111
1.17
0.15
1.8
1.4
—
—
—
0
0
6
77
0.78
0.15
2.0
2.5
—
—
—
0
0
10
119
0.84
0.15
1.2
1.0
—
—
—
0
0
16
140
1.15
0.15
1.1
1.1
113.9
116.3
%
0.11
16
130
17
150
1.14
0.14
1.1
1.2
3.8
2.3
u/ml
—
5
46
13
112
1.16
0.14
1.2
1.1
—
—
—
0
0
13
112
1.16
0.14
1.8
1.4
—
—
—
0
0
13
113
1.15
0.13
1.8
1.4
—
—
—
0
0
13
114
1.14
0.12
1.8
1.4
—
—
—
0
0
13
114
1.14
0.12
1.8
1.4
—
—
—
0
0
10
87
1.15
0.09
1.1
1.2
—
—
—
0
0
6
56
1.07
0.08
1.0
1.1
—
—
—
0
0
7
68
1.03
0.08
1.0
1.1
—
1.7
nmol/l
—
0
12
8
74
1.08
0.07
1.4
1.2
—
—
—
0
0
18
194
0.93
0.07
1.6
2.4
7.2
67.4
ug/min
2.93
11
118
28
265
1.06
0.07
1.6
1.7
—
—
—
0
0
11
99
1.11
0.06
1.2
1.8
91.9
90.3
%
0.65
11
99
51
526
0.97
0.05
1.5
1.5
—
—
—
0
0
36
346
1.04
0.05
2.5
1.8
—
—
—
0
0
12
110
1.09
0.05
1.1
1.1
94.1
95.8
%
0.08
12
102
47
483
0.97
0.04
13.6
9.2
1.1
1.3
%
2.00
47
478
22
230
0.96
0.03
1.4
1.2
—
—
—
0
0
49
480
1.02
0.02
14.1
9.3
0.6
0.7
%
1.00
49
475
25
256
0.98
0.00
2.2
1.9
2.6
4.9
iu/l
2.13
13
96
16
164
0.98
0.00
2.4
3.0
6.7
7.6
mmol/l
1.32
16
159
18
175
1.03
0.00
2.3
2.9
1.3
1.5
mmol/l
0.94
18
169
5
49
1.02
0.00
1.6
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
58
0.86
0.00
1.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.0
1.3
—
—
—
0
0
5
52
0.96
0.00
2.0
1.5
1.8
5.5
u/field
—
5
40
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_EUSTNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EUSTNAS | 1.042 [0.88, 1.23] | 0.633 |
| Birth year | 0.993 [0.98, 1.0] | 0.101 |
During the follow-up period (1.1.1998 — 31.12.2019), 209 out of 2905 females with H8_EUSTNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EUSTNAS | 1.333 [1.11, 1.6] | 0.002 |
| Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 270 out of 1926 males with H8_EUSTNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_EUSTNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.114% | 0.267% |
| 5 | 0.58% | 1.539% |
| 10 | 1.468% | 3.684% |
| 15 | 2.676% | 6.729% |
| 20 | 4.803% | 11.652% |
Relationships between endpoints
↥Index endpoint: H8_EUSTNAS – Other disorders of Eustachian tube
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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