Other bacterial agents as the cause of diseases classified to other chapters

AB1_OTHER_BACT_INOTHER

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B96
  • Cause of death: ICD-10 B96

2 out of 7 registries used, show all original rules.

375

4. Check minimum number of events

None

375

5. Include endpoints

None

375

6. Filter based on genotype QC (FinnGen only)

365

Control definitions (FinnGen only)

Control exclude
AB1_BACT_BIR_OTHER_INF_AGENTS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3169 1962 1175
Only index persons 2334 1415 919
Unadjusted period prevalence (%)
Whole population 0.05 0.06 0.03
Only index persons 0.05 0.05 0.04
Median age at first event (years)
Whole population 62.07 63.04 60.18
Only index persons 53.67 53.02 54.69

-FinnGen-

Key figures

All Female Male
Number of individuals 365 221 144
Unadjusted period prevalence (%) 0.07 0.08 0.07
Median age at first event (years) 57.90 54.10 63.75

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
375
Matched controls
3750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B96.2
ICD-10 Finland
Escherichia coli [E. coli] as the cause of diseases classified to other chapters
+∞
152.9
136
*
B96.5
ICD-10 Finland
Pseudomonas (aeruginosa) as the cause of diseases classified to other chapters
+∞
100.7
92
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
9.2
99.8
172
317
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
15.9
84.6
79
62
B96.1
ICD-10 Finland
Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
+∞
51.2
48
*
A41.9
ICD-10 Finland
Sepsis, unspecified
11.2
50.5
57
59
A41.8
ICD-10 Finland
Other specified sepsis
15.9
44.9
40
28
J01MA02
ATC
ciprofloxacin; systemic
4.3
42.3
231
1020
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.1
38.3
99
248
J01MA12
ATC
levofloxacin; systemic
4.2
36.1
131
425
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
4.1
32.8
119
383
R50.9
ICD-10 Finland
Fever, unspecified
4.1
32.2
113
355
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.5
26.0
55
114
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.8
23.9
88
281
B96.80
ICD-10 Finland
Campylo bacterial infection causing disease classified in other paragraph
+∞
23.2
22
*
J47
ICD-10 Finland
Bronchiectasis
10.0
22.9
27
29
A11CC03
ATC
alfacalcidol; systemic
8.9
22.6
29
35
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.1
22.2
50
109
B96.88
ICD-10 Finland
Other specified bacterial agents as the cause of diseases classified to other chapters
233.0
21.8
22
*
J01GB01
ATC
tobramycin; inhalant, parenteral
199.6
18.7
19
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.3
18.5
28
41
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.1
18.4
92
352
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
18.2
116
508
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.7
18.2
45
106
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
17.9
137
659
B96.0
ICD-10 Finland
Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
+∞
17.8
17
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
17.7
103
428
C03CA01
ATC
furosemide; systemic
2.6
17.7
161
842
127
Kela drug reimbursment
Transplant complication
18.1
17.7
27
16
J01EA01
ATC
trimethoprim; systemic
2.6
17.5
144
716
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
13.0
16.6
29
24
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.9
16.5
53
152
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
12.5
16.3
29
25
B99
ICD-10 Finland
Other and unspecified infectious diseases
7.2
16.3
25
37
TK800
NOMESCO Finland
Hemodialysis
13.1
16.1
28
23
J01FF01
ATC
clindamycin; systemic
2.6
15.9
128
625
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.8
15.3
36
81
J01MA14
ATC
moxifloxacin; systemic
3.6
15.2
56
176
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.3
15.1
42
108
UKC02
NOMESCO Finland
Cystoscopy
2.9
14.7
84
343
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.1
14.7
26
45
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.6
14.4
36
85
TQW11
NOMESCO Finland
Vacuum treatment of wound
6.8
13.8
22
34
ZX120
NOMESCO Finland
Intravenous
3.2
13.4
60
213
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
13.1
198
1249
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.1
13.1
38
101
L04AA01
ATC
[U] ciclosporin
23.5
13.0
18
8
N30.9
ICD-10 Finland
Cystitis, unspecified
3.7
12.9
44
131
J01MA06
ATC
norfloxacin; oral
2.8
12.8
76
315
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
12.7
155
894
L04AA06
ATC
mycophenolic acid; systemic
11.6
12.7
23
21
J01XB01
ATC
colistin; inhalant, parenteral
134.3
12.5
13
*
GD1AD
NOMESCO Finland
Thorax CT examination
4.0
12.1
36
97
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
11.8
90
421
B96.7
ICD-10 Finland
Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
123.7
11.5
12
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
11.4
57
215
Z94.0
ICD-10 Finland
Kidney transplant status
25.9
11.2
15
6
L04AX01
ATC
azathioprine; systemic
4.7
11.1
26
58
Z49.1
ICD-10 Finland
Extracorporeal dialysis
16.1
10.9
17
11
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
10.9
57
220
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.5
10.9
39
120
H02AB07
ATC
prednisone; oral
2.6
10.9
69
295
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
10.7
114
614
L04AD01
ATC
ciclosporin; systemic
10.5
10.6
20
20
J01XE01
ATC
nitrofurantoin; oral
5.7
10.5
20
37
H02AB06
ATC
prednisolone; systemic
2.0
10.3
192
1276
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.4
10.3
26
62
Z3231
NOMESCO Finland
Registered nurse
2.1
10.1
127
730
J01MA01
ATC
ofloxacin; systemic
2.9
9.9
49
183
J01DC02
ATC
cefuroxime; systemic
3.8
9.9
31
87
A07AA09
ATC
vancomycin; oral
13.9
9.8
16
12
JN3AD
NOMESCO Finland
Abdominal CT examination
2.7
9.7
55
221
WX882
NOMESCO Finland
High dependency care
5.0
9.7
21
44
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.9
9.7
48
180
N03AX16
ATC
[U] pregabalin
2.2
9.6
102
546
Z49.0
ICD-10 Finland
Preparatory care for dialysis
18.1
9.5
14
8
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.2
9.4
25
62
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
9.4
81
398
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
9.3
206
1435
H02AB04
ATC
methylprednisolone; systemic
2.5
9.3
67
304
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
10.4
9.1
17
17
B03XA02
ATC
darbepoetin alfa; parenteral
7.8
9.1
20
27
L89
ICD-10 Finland
Decubitus ulcer and pressure area
8.3
9.0
19
24
A12AA04
ATC
calcium carbonate; oral
9.8
8.9
17
18
N18.8
ICD-10 Finland
Other chronic renal failure
6.9
8.8
21
32
M04AA01
ATC
allopurinol; systemic
2.5
8.7
62
279
N18.0
ICD-10 Finland
End-stage renal disease
16.8
8.6
13
8
Z49.2
ICD-10 Finland
Other dialysis
28.2
8.5
11
*
137
Kela drug reimbursment
Uraemia requiring dialysis
20.6
8.5
12
6
N30.0
ICD-10 Finland
Acute cystitis
2.3
8.5
75
371
J01DA01
ATC
[U] cefalexin
1.9
8.5
237
1764
A07AA02
ATC
nystatin; oral
3.3
8.5
33
107
ZXD05
NOMESCO Finland
Urgent procedure
2.0
8.4
126
763
JN4BD
NOMESCO Finland
Extensive body CT
2.6
8.4
53
225
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
8.3
124
750
L28
ICPC
Limited function/disability (L)
2.2
8.3
80
411
Z2446
NOMESCO Finland
Social worker
2.9
8.2
41
154
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.9
8.2
18
38
A10AB05
ATC
insulin aspart; parenteral
2.8
8.2
42
160
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
4.2
8.2
22
55
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
8.2
87
464
J45.1
ICD-10 Finland
Nonallergic asthma
2.9
8.1
40
149
WW500
NOMESCO Finland
Blood transfusion
3.6
8.1
27
79
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
8.1
38
138
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
6.8
8.0
19
29
WX892
NOMESCO Finland
Monitored bed care
2.9
8.0
38
139
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
4.8
8.0
18
39
A10AC01
ATC
insulin (human); parenteral
2.7
7.8
44
176
WX872
NOMESCO Finland
Intensive care
3.6
7.8
26
76
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.7
7.7
43
171
A46
ICD-10 Finland
Erysipelas
2.3
7.7
61
287
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
25.6
7.6
10
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.1
7.6
81
432
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
7.5
146
957
TKC20
NOMESCO Finland
Catheterisation of bladder
2.9
7.5
37
138
B03XA01
ATC
erythropoietin; parenteral
13.7
7.4
12
9
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
13.7
7.4
12
9
UDC00
NOMESCO Finland
Ear microscopy
2.7
7.4
40
157
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
7.4
62
300
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
11.2
7.3
13
12
C03DA01
ATC
spironolactone; oral
2.3
7.3
59
280
QBG00
NOMESCO Finland
Debridement of bedsore of trunk
+∞
7.3
7
*
U88
ICD-10 Finland
Agent resistant to multiple antibiotics
+∞
7.3
7
*
H02AB09
ATC
hydrocortisone; systemic
4.6
7.2
17
38
R03AK08
ATC
formoterol and beclometasone; inhalant
3.6
7.2
24
70
UJF32
NOMESCO Finland
Coloscopy
2.0
7.2
102
601
K57.0
ICD-10 Finland
Diverticular disease of small intestine with perforation and abscess
30.6
7.2
9
*
QBB99
NOMESCO Finland
Other procedure for wound of skin of trunk
30.6
7.2
9
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
30.6
7.2
9
*
N06AB04
ATC
citalopram; systemic
2.0
7.1
86
479
XW000
NOMESCO Finland
Bone marrow biopsy
3.5
7.1
25
76
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
7.0
140
921
N05CF01
ATC
zopiclone; oral
1.8
7.0
132
853
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.1
7.0
19
48
3AC01, ,
NOMESCO Finland
14.1
6.9
11
8
WW200
NOMESCO Finland
Immunization
5.9
6.8
18
32
ZXE00
NOMESCO Finland
One hour or less
1.8
6.8
153
1040
G04AC01, ,
ATC
3.6
6.8
22
63
B05DA
ATC
Isotonic solutions
23.0
6.7
9
*
N02AX02
ATC
tramadol; systemic, rectal
1.8
6.7
161
1117
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
6.6
66
341
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
6.6
51
238
A02BC01
ATC
omeprazole; systemic
1.9
6.5
112
700
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
71.0
6.4
7
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.9
6.4
19
51
JN4AD
NOMESCO Finland
Body CT examination
2.5
6.4
42
181
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.4
6.4
44
194
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
18.4
6.3
9
5
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
18.4
6.3
9
5
N05CD07
ATC
temazepam; oral
2.2
6.3
56
277
J02AC01
ATC
fluconazole; systemic
1.8
6.3
144
981
J20.8
ICD-10 Finland
Acute bronchitis due to other specified organisms
+∞
6.3
6
*
J41.1
ICD-10 Finland
Mucopurulent chronic bronchitis
27.2
6.3
8
*
KH1AD
NOMESCO Finland
CT of urinary organs
4.1
6.2
17
43
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.9
6.2
29
105
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
6.1
78
441
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
6.1
137
925
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
6.1
43
192
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.3
6.1
17
33
L04AD02
ATC
tacrolimus; systemic
10.3
6.1
11
11
J01DB01
ATC
cefalexin; oral
1.9
6.1
302
2553
J01CA08
ATC
pivmecillinam; oral
1.7
6.1
161
1140
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
6.1
47
219

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
187
814
3.59
32.79
10.6
4.1
—
—
—
0
0
37
41
9.90
30.87
11.2
3.1
—
—
—
0
0
110
460
2.97
18.86
7.3
4.1
0.80
0.81
mmol/l
0.32
101
432
70
226
3.58
18.40
3.4
2.8
9.76
10.13
g/l
0.33
64
208
100
420
2.88
16.81
4.4
2.3
2.10
2.35
g/l
3.58
93
383
59
190
3.50
15.46
2.7
1.7
1.49
1.75
g/l
0.21
52
172
212
1324
2.38
15.09
13.3
6.2
0.62
0.65
%
0.40
201
1240
86
352
2.87
15.01
3.3
1.7
—
—
—
0
0
93
398
2.78
14.92
4.8
2.3
16.51
22.62
%
6.23
85
350
217
1378
2.36
14.74
14.0
6.7
—
—
—
0
0
216
1374
2.35
14.54
13.6
6.5
8.41
8.51
%
0.21
205
1300
214
1367
2.32
14.11
13.2
6.2
2.54
2.86
%
1.51
203
1286
73
284
2.95
13.91
8.3
4.2
1.56
1.78
mmol/l
0.22
66
221
200
1248
2.29
13.87
9.0
4.8
32.71
35.43
g/l
7.01
181
1173
218
1411
2.30
13.83
13.6
6.3
25.28
27.82
%
2.46
207
1338
98
449
2.60
13.63
3.7
1.9
—
—
—
0
0
215
1398
2.26
13.30
12.7
6.1
60.74
57.18
%
3.95
203
1325
22
36
6.43
13.08
6.1
3.9
—
—
—
0
0
235
1597
2.26
12.89
11.2
6.4
10.11
11.40
umol/l
1.55
220
1502
64
247
2.92
12.30
16.2
9.7
—
—
—
0
0
79
345
2.63
11.98
4.2
3.1
1.93
1.80
%
0.27
68
316
222
1512
2.15
11.61
13.3
6.2
0.19
0.19
e9/l
0.22
201
1330
244
1732
2.17
11.36
16.4
9.3
4.53
4.15
e9/l
1.58
218
1522
217
1474
2.12
11.32
12.7
6.0
0.04
0.04
e9/l
0.12
198
1280
121
656
2.25
11.31
5.9
2.9
503.26
549.33
mosm/kgh2o
1.83
104
562
216
1469
2.11
11.18
12.7
6.0
0.61
0.58
e9/l
1.77
197
1273
144
845
2.14
10.98
6.3
2.9
—
—
—
0
0
219
1514
2.07
10.65
13.1
6.0
1.71
1.84
e9/l
1.61
203
1342
61
248
2.74
10.59
4.8
2.9
74.94
72.40
e9/l
0.10
44
190
66
282
2.63
10.38
3.5
2.2
0.20
0.21
g/l
0.60
61
265
58
232
2.77
10.37
8.9
3.7
131.01
76.86
ng/l
3.04
49
209
146
877
2.09
10.34
6.4
3.0
0.56
0.53
e6/l
0.04
123
670
57
227
2.78
10.28
5.5
4.9
0.23
0.11
%
0.35
30
79
55
217
2.80
10.09
5.5
4.6
0.71
0.53
%
0.38
28
78
120
677
2.14
9.96
5.1
2.5
5.33
6.31
e6/l
0.29
106
611
213
1485
2.01
9.80
16.9
6.8
1.21
1.22
mmol/l
0.74
178
1256
153
961
2.00
9.38
6.6
3.2
26.65
126.06
e6/l
0.85
128
749
58
245
2.62
9.30
5.5
4.7
0.85
0.85
%
0.00
31
98
23
54
4.47
9.26
6.7
3.1
51.83
59.69
%
2.15
23
54
54
223
2.66
9.05
9.4
5.2
7.42
7.41
ph
0.28
12
26
37
124
3.20
9.01
2.1
2.2
1.71
1.56
g/l
0.43
31
106
116
669
2.06
8.95
1.7
1.4
2.39
2.38
g/l
0.01
79
399
184
1246
1.94
8.94
3.6
2.3
79.92
77.38
nmol/l
0.53
165
1109
155
1010
1.91
8.30
4.9
3.1
—
—
—
0
0
71
348
2.28
8.21
2.5
1.4
—
—
—
0
0
189
1318
1.87
8.16
4.8
2.7
207.25
110.71
ug/l
2.04
167
1210
166
1115
1.88
8.03
7.5
3.8
50.11
89.08
e6/l
1.27
135
801
54
237
2.49
7.97
3.5
3.1
64.52
66.24
g/l
0.91
48
216
50
214
2.54
7.78
6.0
5.1
0.04
0.15
%
0.38
23
67
24
67
3.76
7.71
2.2
1.7
—
—
—
0
0
236
1789
1.86
7.59
9.1
4.9
6.90
6.67
mmol/l
0.79
225
1649
197
1414
1.83
7.56
22.8
13.8
1.33
1.26
inr
0.51
66
433
28
89
3.32
7.42
2.6
4.3
251.41
29.63
mg/l
0.48
20
68
171
1188
1.81
7.20
2.2
2.0
89.07
95.61
pmol/l
1.12
91
594
143
941
1.84
7.20
4.4
2.5
51.00
55.30
u/l
0.69
134
871
69
352
2.18
7.20
5.2
3.1
8.33
8.93
umol/l
0.10
55
307
45
192
2.53
7.04
3.6
2.6
—
—
—
0
0
27
89
3.19
6.76
2.6
4.3
51.65
59.69
mg/l
0.16
20
68
22
65
3.53
6.52
8.2
2.4
—
—
—
0
0
87
501
1.96
6.51
5.0
2.9
1.94
2.55
e6/l
0.50
61
281
141
951
1.77
6.38
4.5
2.4
—
—
—
0
0
279
2288
1.86
6.34
16.5
7.5
90.44
79.06
u/l
2.06
263
2136
20
59
3.52
5.95
2.1
1.6
—
—
—
0
0
23
75
3.20
5.87
1.3
1.2
—
—
—
0
0
184
1360
1.69
5.86
15.9
6.2
1.20
1.22
mmol/l
1.55
169
1237
22
70
3.28
5.84
6.7
2.2
15.37
16.14
%
0.36
16
33
119
781
1.77
5.82
3.4
2.0
3.47
3.06
mg/l
0.79
104
668
92
560
1.85
5.77
2.0
1.7
960.16
1230.54
nmol/l
2.44
60
416
42
191
2.35
5.73
4.3
2.0
3.83
6.30
e9/l
1.00
27
156
20
61
3.41
5.66
5.9
3.0
—
—
—
0
0
251
2028
1.72
5.62
8.3
4.7
7005.17
1849.81
e6/l
—
6
36
10
10
10.23
5.56
2.2
2.5
—
—
—
0
0
21
67
3.26
5.55
2.5
4.9
—
—
—
0
0
38
170
2.37
5.38
1.3
1.3
—
—
—
0
0
9
8
11.49
5.31
1.9
1.5
—
—
—
0
0
132
912
1.69
5.29
11.0
3.8
7.40
7.40
ph
0.05
38
182
14
27
5.34
5.13
1.2
1.2
—
—
—
0
0
126
878
1.66
4.81
4.9
4.0
—
—
—
0
0
106
706
1.70
4.80
4.3
2.7
367.76
5459.95
umol/l
2.63
91
615
57
314
1.96
4.79
12.4
8.1
0.93
1.21
mmol/l
0.18
46
255
263
2195
1.66
4.79
7.0
4.1
20.39
11.74
mm/h
6.65
240
2014
36
166
2.29
4.77
9.9
5.8
—
—
—
0
0
57
315
1.95
4.75
12.4
8.0
11.59
11.81
kpa
0.15
52
304
71
422
1.84
4.74
1.2
1.3
—
—
—
0
0
251
2078
1.63
4.64
8.4
4.4
—
—
—
0
0
102
679
1.69
4.61
4.5
2.0
1.29
1.28
mg/l
0.01
82
530
7
5
14.23
4.59
8.4
2.0
—
—
—
0
0
159
1185
1.59
4.57
4.9
3.6
5.92
5.81
ph
—
6
78
17
55
3.19
4.42
9.3
2.6
—
—
—
0
0
49
264
1.98
4.38
1.9
1.4
—
—
—
0
0
104
706
1.65
4.33
1.7
1.5
20.23
20.91
nmol/l
0.14
86
596
86
555
1.71
4.33
2.3
1.9
—
—
—
0
0
10
16
6.39
4.32
3.5
2.4
—
—
—
0
0
137
1004
1.57
4.14
4.0
3.3
2.33
2.36
mmol/l
1.16
116
882
128
926
1.58
4.08
4.7
3.3
2359.59
1283.72
ng/l
1.32
112
781
108
752
1.61
4.03
12.0
7.3
—
—
—
0
0
179
1401
1.53
3.99
4.1
2.6
—
—
—
0
0
47
259
1.93
3.95
2.3
2.3
18.30
7.35
ug/l
0.61
36
226
14
43
3.34
3.94
2.7
1.7
88.49
90.49
%
0.36
14
43
188
1492
1.52
3.90
6.2
3.8
0.00
0.00
estimate
-0.00
47
338
59
352
1.80
3.88
2.3
1.6
—
—
—
0
0
188
1496
1.51
3.82
8.3
5.1
0.00
0.00
estimate
-0.00
44
314
22
90
2.53
3.79
7.8
3.3
—
—
—
0
0
52
301
1.84
3.77
4.7
2.2
50.93
31.94
u/l
0.36
44
254
12
30
4.10
3.62
1.1
1.2
—
—
—
0
0
189
1518
1.49
3.60
6.2
3.9
0.00
0.01
estimate
0.50
44
303
7
9
7.90
3.57
1.6
2.4
—
—
—
0
0
7
9
7.90
3.57
1.6
1.4
—
—
—
0
0
11
26
4.33
3.53
3.3
2.7
—
—
—
0
0
13
36
3.70
3.53
4.0
2.4
—
—
—
0
0
12
31
3.96
3.52
1.2
1.4
—
—
—
0
0
73
477
1.66
3.47
5.5
2.9
30.62
29.97
s
0.35
68
464
16
58
2.84
3.46
2.4
1.7
—
—
—
0
0
16
58
2.84
3.46
6.8
3.1
—
—
—
0
0
13
38
3.51
3.34
2.1
1.2
—
—
—
0
0
170
1353
1.47
3.31
22.4
10.2
0.00
0.00
e9/l
0.61
146
1110
12
34
3.61
3.22
2.3
2.7
—
—
—
0
0
39
217
1.89
3.20
2.0
1.5
—
—
—
0
0
30
152
2.06
3.20
5.8
3.7
—
—
—
0
0
59
374
1.69
3.14
3.3
2.2
165.89
136.77
ug/g
0.24
45
286
70
469
1.61
3.01
2.4
1.6
—
—
—
0
0
12
37
3.32
2.96
6.5
2.6
—
—
—
0
0
24
116
2.14
2.90
2.5
1.9
—
—
—
0
0
7
13
5.46
2.88
2.3
1.8
38.79
59.56
ug/l
—
7
13
20
90
2.29
2.85
1.4
1.4
212.27
268.70
ug/g
0.54
11
52
95
693
1.50
2.79
5.1
3.7
—
—
—
0
0
33
183
1.88
2.75
4.2
4.2
—
—
—
0
0
10
29
3.51
2.71
1.9
1.8
—
—
—
0
0
6
10
6.08
2.71
1.2
1.0
—
—
—
0
0
11
35
3.21
2.66
2.2
2.0
32.18
33.00
pg
0.30
11
35
146
1167
1.41
2.62
5.3
3.8
30.62
41.92
ng/l
1.12
118
834
12
42
2.92
2.57
3.7
3.1
—
—
—
0
0
119
925
1.42
2.48
3.7
2.1
120.35
306.23
u/l
1.77
112
868
43
271
1.66
2.36
10.0
4.3
—
—
—
0
0
11
41
2.73
2.22
1.2
1.2
—
—
—
0
0
6
14
4.34
2.16
1.3
1.4
—
—
—
0
0
217
1893
1.35
2.13
4.8
3.1
71.79
46.88
u/l
1.33
200
1776
6
15
4.05
2.04
2.0
1.9
—
—
—
0
0
6
15
4.05
2.04
4.5
1.3
0.50
1.40
u/field
—
6
10
8
26
3.12
2.02
1.0
1.1
—
—
—
0
0
140
1155
1.34
1.96
2.5
2.1
—
—
—
0
0
42
277
1.58
1.95
9.3
3.6
—
—
—
0
0
11
45
2.49
1.94
2.4
2.6
—
—
—
0
0
5
11
4.59
1.94
1.0
1.3
—
—
—
0
0
76
569
1.42
1.92
4.4
3.8
133.03
272.00
ng/l
0.70
68
449
9
34
2.69
1.87
1.0
1.0
—
—
—
0
0
9
34
2.69
1.87
1.0
1.1
—
—
—
0
0
8
28
2.90
1.87
2.5
1.4
—
—
—
0
0
11
46
2.43
1.87
2.4
2.6
105.00
105.78
mmol/l
0.29
11
46
11
46
2.43
1.87
2.4
2.6
4.03
4.04
mmol/l
0.04
11
46
6
17
3.57
1.84
1.3
1.4
—
—
—
0
0
8
29
2.80
1.80
1.9
1.0
—
—
—
0
0
29
179
1.67
1.75
3.1
3.5
4.43
4.63
pmol/l
0.54
24
157
8
30
2.70
1.73
1.1
1.2
—
—
—
0
0
8
30
2.70
1.73
8.9
2.5
—
—
—
0
0
46
319
1.50
1.73
3.6
3.9
60.66
40.11
ug/l
0.14
39
270
52
373
1.46
1.66
1.5
1.3
336.00
555.06
titre
—
10
89
7
25
2.83
1.65
1.1
1.1
—
—
—
0
0
17
91
1.91
1.63
8.7
4.2
—
—
—
0
0
10
42
2.42
1.63
3.1
1.4
—
—
—
0
0
24
144
1.71
1.62
22.8
10.6
—
—
—
0
0
11
50
2.24
1.58
2.8
1.5
—
—
—
0
0
11
50
2.24
1.58
1.5
1.5
—
—
—
0
0
37
250
1.53
1.57
1.9
1.5
—
—
—
0
0
18
100
1.84
1.56
1.4
1.6
—
—
—
0
0
5
15
3.36
1.53
4.2
1.6
1321.80
888.20
u/ml
—
5
15
5
15
3.36
1.53
1.0
2.3
—
—
—
0
0
73
565
1.36
1.52
3.6
2.8
2.44
2.45
mmol/l
0.09
59
494
313
2945
1.38
1.52
43.9
14.7
31.30
23.09
mg/l
3.65
288
2340
14
72
1.98
1.51
3.1
2.8
—
—
—
0
0
5
17
2.97
1.36
2.6
1.1
—
—
—
0
0
80
642
1.31
1.32
1.7
1.7
510.13
12547273.79
pmol/l
0.50
63
534
18
106
1.73
1.32
1.3
1.2
—
—
—
0
0
8
35
2.31
1.27
1.3
1.1
—
—
—
0
0
105
879
1.27
1.25
4.7
3.2
6.43
7.55
mmol/l
1.37
76
747
18
108
1.70
1.24
1.4
1.4
—
—
—
0
0
30
207
1.49
1.19
2.8
2.8
—
—
—
0
0
49
371
1.37
1.19
1.2
1.3
—
—
—
0
0
100
840
1.26
1.16
5.7
3.9
31.27
9.04
mg/mmol
1.46
58
541
0
36
0.00
1.14
0.0
1.4
—
275.08
—
0
26
89
744
1.26
1.07
1.2
1.3
0.59
1.50
u/ml
2.00
17
207
100
849
1.24
1.05
6.5
3.5
—
—
—
0
0
9
46
1.98
1.04
2.0
1.7
—
—
—
0
0
5
22
2.29
1.03
2.4
1.5
—
—
—
0
0
25
173
1.48
1.00
4.5
3.2
0.08
0.16
e6/l
0.60
25
168
0
29
0.00
0.98
0.0
1.7
—
—
—
0
0
44
340
1.33
0.96
1.3
1.3
—
—
—
0
0
0
32
0.00
0.95
0.0
3.0
—
—
—
0
0
33
244
1.39
0.95
3.5
3.6
—
—
—
0
0
6
27
2.24
0.94
1.8
3.0
—
—
—
0
0
94
804
1.23
0.92
4.6
3.3
134.66
284.07
mg/l
0.54
58
528
27
194
1.42
0.91
1.3
1.2
—
—
—
0
0
8
43
1.88
0.88
1.4
1.3
—
—
—
0
0
12
73
1.67
0.82
1.3
2.2
9.57
11.49
mg/l
0.51
12
67
6
32
1.89
0.82
2.5
1.3
—
—
—
0
0
8
47
1.72
0.81
1.3
1.2
—
—
—
0
0
17
114
1.51
0.81
3.6
2.6
—
—
—
0
0
17
115
1.50
0.78
5.6
3.9
0.71
0.20
g/l
0.94
11
52
0
27
0.00
0.77
0.0
4.0
—
17.80
—
0
21
6
34
1.78
0.76
2.5
1.4
—
—
—
0
0
267
2795
0.84
0.75
5.3
4.5
6.05
5.92
mmol/l
0.67
231
2534
7
38
1.86
0.74
1.1
1.3
—
—
—
0
0
58
484
1.23
0.73
1.3
1.3
27.10
35.91
iu/ml
0.43
24
162
5
25
2.01
0.73
1.8
1.2
—
—
—
0
0
11
68
1.64
0.72
1.4
1.3
—
—
—
0
0
9
59
1.54
0.69
1.3
1.9
—
—
—
0
0
86
977
0.84
0.68
3.4
2.9
—
—
—
0
0
189
2018
0.87
0.64
5.1
3.9
—
—
—
0
0
16
222
0.71
0.63
1.3
1.3
—
—
—
0
0
5
30
1.68
0.61
1.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.6
—
1.63
—
0
16
0
23
0.00
0.58
0.0
1.5
—
69.87
—
0
23
6
35
1.73
0.58
1.8
1.4
—
—
—
0
0
18
133
1.37
0.56
1.1
1.0
—
—
—
0
0
12
82
1.48
0.55
4.5
2.1
112.43
62.13
ug/min
—
7
43
6
39
1.55
0.53
1.2
1.0
—
—
—
0
0
42
496
0.83
0.52
3.0
3.1
1.38
0.76
ug/l
0.31
27
338
94
848
1.14
0.51
7.3
4.2
0.00
0.00
estimate
-0.00
42
304
320
3274
0.85
0.50
52.4
21.3
4.25
4.46
e12/l
10.52
313
3166
320
3274
0.85
0.50
52.2
21.2
30.02
30.23
pg
1.17
314
3216
320
3274
0.85
0.50
52.5
21.3
7.38
6.70
e9/l
2.87
313
3164
320
3273
0.85
0.49
52.3
21.2
91.22
90.92
fl
0.50
314
3216
320
3273
0.85
0.49
53.8
21.4
38.20
39.81
%
5.19
307
3081
15
110
1.38
0.49
6.1
4.8
—
—
—
0
0
320
3272
0.85
0.48
52.4
21.3
260.73
250.09
e9/l
1.61
313
3175
68
763
0.87
0.47
1.8
1.6
1.33
1.32
mmol/l
0.05
54
639
9
131
0.68
0.43
2.1
1.7
—
—
—
0
0
309
3012
1.15
0.43
43.2
16.7
139.08
139.61
mmol/l
3.03
303
2918
235
2439
0.90
0.41
42.8
18.9
329.10
332.03
g/l
4.36
229
2421
0
16
0.00
0.41
0.0
1.5
—
1.58
—
0
16
0
16
0.00
0.41
0.0
1.3
—
203.54
—
0
16
27
223
1.23
0.41
1.4
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
8.6
—
0.62
—
0
17
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.48
0.40
15.4
4.6
413.20
352.72
umol/l
—
5
29
6
41
1.47
0.36
1.2
1.3
—
75.14
—
0
5
17
135
1.27
0.36
1.1
1.2
—
—
—
0
0
12
156
0.76
0.35
1.3
1.4
—
—
—
0
0
308
3015
1.12
0.34
44.1
16.8
4.03
3.97
mmol/l
2.73
302
2919
277
2839
0.91
0.33
5.0
4.9
2.64
2.70
mmol/l
0.53
242
2600
88
814
1.11
0.33
1.7
1.5
—
—
—
0
0
11
84
1.32
0.30
1.3
1.6
—
—
—
0
0
250
2569
0.92
0.30
43.5
17.7
15.47
14.88
%
0.92
244
2528
5
72
0.69
0.26
2.2
1.4
—
—
—
0
0
232
2258
1.07
0.24
4.1
4.0
14.50
14.85
pmol/l
1.29
202
2023
52
476
1.11
0.24
1.4
1.3
4.08
11.06
u/ml
1.01
18
194
6
81
0.74
0.24
1.2
1.3
—
—
—
0
0
5
38
1.32
0.23
1.8
1.4
—
—
—
0
0
5
40
1.25
0.22
1.6
1.2
—
—
—
0
0
5
42
1.19
0.21
1.0
1.0
—
—
—
0
0
18
154
1.18
0.21
2.4
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
271
2760
0.93
0.21
4.8
4.4
1.42
1.49
mmol/l
1.47
237
2532
13
108
1.21
0.20
1.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
3.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
6
51
1.18
0.19
1.5
1.7
4.56
5.30
mmol/24h
—
6
43
7
59
1.19
0.18
2.1
3.5
35.29
28.84
u/ml
—
7
59
80
842
0.94
0.18
4.3
5.2
4.54
2.67
ug/l
0.25
68
745
5
69
0.72
0.17
1.8
1.4
—
—
—
0
0
64
676
0.94
0.16
5.9
4.2
1.02
1.02
kg/l
—
8
87
274
2779
0.95
0.15
4.7
4.4
4.54
4.60
mmol/l
0.39
238
2562
13
112
1.17
0.14
1.3
1.6
—
—
—
0
0
13
112
1.17
0.14
2.2
1.6
13.81
23.32
iu/l
—
8
95
13
112
1.17
0.14
1.3
1.6
—
—
—
0
0
29
267
1.09
0.13
1.9
1.6
—
—
—
0
0
13
113
1.16
0.13
1.3
1.6
—
—
—
0
0
9
108
0.83
0.13
1.0
1.0
—
—
—
0
0
19
209
0.90
0.11
1.4
1.2
20.91
134.78
iu/ml
—
7
82
29
311
0.93
0.11
1.8
1.7
—
—
—
0
0
275
2725
1.03
0.08
5.2
4.8
1.81
1.90
mu/l
0.60
241
2463
8
74
1.08
0.07
1.5
2.1
—
—
—
0
0
264
2659
0.98
0.05
4.5
4.0
1.38
1.25
mmol/l
1.76
229
2428
28
293
0.95
0.05
1.9
1.8
—
—
—
0
0
17
159
1.07
0.05
1.9
3.0
97.29
38.07
u/ml
0.74
17
153
264
2624
1.02
0.04
7.7
5.8
42.02
39.86
mmol/mol
1.92
239
2429
12
111
1.08
0.04
1.1
1.6
—
—
—
0
0
311
3100
1.02
0.02
20.6
10.4
25.01
24.91
u/l
0.04
300
2979
306
3069
0.98
0.02
34.2
13.5
—
—
—
0
0
16
162
0.99
0.00
1.1
1.1
—
6.20
—
0
5
11
105
1.05
0.00
1.3
1.7
—
—
—
0
0
26
264
0.98
0.00
1.1
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
3.43
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
18.25
—
0
6
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
8
84
0.95
-0.00
1.4
1.3
—
—
—
0
0
9
93
0.97
-0.00
18.3
10.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
18.60
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
48.80
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
77
0.91
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_OTHER_BACT_INOTHER and mortality.

Females

Parameter HR [95% CI] p-value
AB1_OTHER_BACT_INOTHER 2.026 [1.66, 2.48] < 0.001
Birth year 0.995 [0.99, 1.0] 0.22

During the follow-up period (1.1.1998 — 31.12.2019), 562 out of 1325 females with AB1_OTHER_BACT_INOTHER died.

Males

Parameter HR [95% CI] p-value
AB1_OTHER_BACT_INOTHER 2.755 [2.11, 3.59] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 352 out of 852 males with AB1_OTHER_BACT_INOTHER died.

Mortality risk

Mortality risk for people of age

years, who have AB1_OTHER_BACT_INOTHER.

N-year risk Females Males
1 0.208% 0.509%
5 1.246% 2.961%
10 3.141% 7.155%
15 5.804% 13.554%
20 10.293% 21.955%

Relationships between endpoints

Index endpoint: AB1_OTHER_BACT_INOTHER – Other bacterial agents as the cause of diseases classified to other chapters

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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