No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
459 |
4. Check minimum number of eventsNone |
459 |
5. Include endpointsNone |
459 |
6. Filter based on genotype QC (FinnGen only) |
459 |
Control definitions (FinnGen only)
- Control exclude
- AB1_ZOONOTIC_BACTERIAL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to Tularaemia based on the number of shared cases.
Similar with more cases:
- Certain zoonotic bacterial diseases
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 4460 | 1976 | 2467 |
Only index persons | 4103 | 1830 | 2273 |
Unadjusted period prevalence (%) | |||
Whole population | 0.06 | 0.06 | 0.07 |
Only index persons | 0.08 | 0.07 | 0.09 |
Median age at first event (years) | |||
Whole population | 46.83 | 48.39 | 45.50 |
Only index persons | 46.01 | 47.63 | 44.71 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 459 | 219 | 240 |
Unadjusted period prevalence (%) | 0.09 | 0.07 | 0.11 |
Median age at first event (years) | 50.58 | 47.45 | 53.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 404
- Matched controls
- 4040
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint AB1_TULARAEMIA and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
AB1_TULARAEMIA | 0.971 [0.78, 1.21] | 0.798 |
Birth year | 0.996 [0.99, 1.0] | 0.411 |
During the follow-up period (1.1.1998 — 31.12.2019), 131 out of 1400 females with AB1_TULARAEMIA died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
AB1_TULARAEMIA | 0.804 [0.68, 0.95] | 0.011 |
Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 193 out of 1871 males with AB1_TULARAEMIA died.
Mortality risk
Mortality risk for people of age
years, who have AB1_TULARAEMIA.N-year risk | Females | Males |
---|---|---|
1 | 0.079% | 0.134% |
5 | 0.564% | 0.855% |
10 | 1.485% | 2.14% |
15 | 2.888% | 4.126% |
20 | 4.936% | 7.341% |
Relationships between endpoints
↥Index endpoint: AB1_TULARAEMIA – Tularaemia
GWS hits: 2