≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback

Certain zoonotic bacterial diseases

DOID EFO Endpoint Browser PheWeb

AB1_ZOONOTIC_BACTERIAL

Yersinia pestis infectious disease: Plague is a severe bacterial infection caused by the gram-negative bacterium Yersinia pestis.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — A20-A28
  • Hospital discharge: ICD-9 — 02[0-7]|B783A
  • Hospital discharge: ICD-8 — 02[0-7]
  • Cause of death: ICD-10 — A20-A28
  • Cause of death: ICD-9 — 02[0-7]|B783A
  • Cause of death: ICD-8 — 02[0-7]

2 out of 7 registries used, show all original rules.

666

4. Check minimum number of events

None

666

5. Include endpoints

666

6. Filter based on genotype QC (FinnGen only)

666

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6494 3019 3435
Only index persons 5630 2662 2968
Unadjusted period prevalence (%)
Whole population 0.09 0.09 0.10
Only index persons 0.11 0.10 0.11
Median age at first event (years)
Whole population 47.98 48.65 47.21
Only index persons 45.99 46.97 45.11

-FinnGen-

Key figures

All Female Male
Number of individuals 666 333 333
Unadjusted period prevalence (%) 0.13 0.11 0.15
Median age at first event (years) 50.04 46.60 53.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
594
Matched controls
5941
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A21.9
ICD-10 Finland
Tularaemia, unspecified
3088.9
215.2
195
*
A21.0
ICD-10 Finland
Ulceroglandular tularaemia
+∞
115.5
107
*
J01MA02
ATC
ciprofloxacin; systemic
3.9
52.8
342
1536
A21.2
ICD-10 Finland
Pulmonary tularaemia
+∞
25.2
24
*
A26.0
ICD-10 Finland
Cutaneous erysipeloid
260.4
24.9
25
*
R50.9
ICD-10 Finland
Fever, unspecified
3.4
24.7
134
464
A21.8
ICD-10 Finland
Other forms of tularaemia
+∞
17.8
17
*
0210A
ICD-9 Finland
Tularaemia, Ulceroglandular tularaemia
+∞
15.7
15
*
02100
ICD-8 Finland
Tularaemia, Glanduraris sive ulceroglandularis
+∞
12.5
12
*
A21
ICD-10 Finland
Tularaemia
+∞
11.5
11
*
B99
ICD-10 Finland
Other and unspecified infectious diseases
7.8
10.8
24
32
A28.9
ICD-10 Finland
Zoonotic bacterial disease, unspecified
+∞
10.4
10
*
0219X
ICD-9 Finland
Tularaemia, Unspecified tularaemia
+∞
10.4
10
*
0218X
ICD-9 Finland
Tularaemia, Other specified tularaemia
+∞
10.4
10
*
A25.1
ICD-10 Finland
Streptobacillosis
+∞
10.4
10
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.6
10.0
73
301
J17.0*A21.2
ICD-10 Finland
Pneumonia (due to)(in) tularaemia
+∞
9.4
9
*
A27.9
ICD-10 Finland
Leptospirosis, unspecified
+∞
9.4
9
*
A98.5
ICD-10 Finland
Haemorrhagic fever with renal syndrome
6.1
8.8
23
39
A26.9
ICD-10 Finland
Erysipeloid, unspecified
+∞
8.3
8
*
J01MA12
ATC
levofloxacin; systemic
2.0
8.0
114
638
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.6
7.8
59
246
0270X
ICD-9 Finland
Other zoonotic bacterial diseases, Listeriosis[LISTERIOSIS ALIA (EI SYNNYNNÄINEN)]
+∞
7.3
7
*
A21.7
ICD-10 Finland
Generalized tularaemia
+∞
7.3
7
*
A28.19
ICD-10 Finland
Other or indefinite cat-scratch fever
+∞
7.3
7
*
A46
ICD-10 Finland
Erysipelas
2.0
6.7
81
425
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
6.3
118
725
02107
ICD-8 Finland
Tularaemia, Suspecta
+∞
6.3
6
*
02109
ICD-8 Finland
Tularaemia, Unspecified
+∞
6.3
6
*
A24.1
ICD-10 Finland
Acute and fulminating melioidosis
+∞
6.3
6
*
M49.1*A23.9
ICD-10 Finland
Brucella spondylitis
+∞
6.3
6
*
SPAT1263
SPAT
Sampling
1.6
6.1
235
1757
J01AA02
ATC
doxycycline; systemic
1.6
6.0
425
3650

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
33
6
57.73
28.40
1.8
1.2
1184.6
—
titre
—
13
0
228
1472
1.83
11.66
4.5
4.3
—
—
—
0
0
81
411
2.11
8.20
3.8
3.0
247.4
196.7
ng/l
0.53
76
375
327
2507
1.60
8.04
7.4
5.9
8.7
8.7
%
0.19
317
2361
326
2500
1.60
7.99
7.0
5.6
2.7
2.9
%
0.60
314
2335
318
2426
1.59
7.96
6.8
5.6
0.7
0.7
%
0.29
308
2273
332
2569
1.58
7.75
6.9
5.7
27.1
27.7
%
0.51
320
2407
20
49
4.18
7.58
1.3
1.1
—
—
—
0
0
327
2537
1.57
7.44
6.8
5.5
58.0
57.2
%
0.67
315
2389
75
385
2.07
7.36
4.7
4.5
0.0
0.1
%
0.94
21
110
75
396
2.01
6.82
4.2
4.3
1.0
0.5
%
0.76
19
104
152
1001
1.67
6.72
4.9
3.7
135.3
340.4
ng/l
1.05
117
783
292
2249
1.53
6.62
5.9
4.7
35.5
35.6
g/l
0.13
270
2102
343
2739
1.52
6.54
6.8
5.7
0.2
0.2
e9/l
0.25
316
2430
341
2722
1.52
6.50
6.6
5.5
1.8
1.9
e9/l
1.71
310
2417
332
2642
1.51
6.38
6.6
5.5
0.6
0.6
e9/l
0.68
304
2297
75
410
1.93
6.18
4.3
4.4
0.0
0.2
%
1.15
23
130
332
2658
1.50
6.10
6.7
5.5
0.0
0.0
e9/l
0.54
304
2320
78
439
1.88
5.89
4.7
4.3
2.0
0.9
%
0.80
23
144
28
108
2.66
5.29
1.1
1.4
—
—
—
0
0
69
400
1.81
4.76
3.3
2.7
10.0
10.7
g/l
0.68
64
364
164
1185
1.51
4.74
5.6
4.4
—
—
—
0
0
192
1443
1.46
4.54
4.2
3.3
—
—
—
0
0
25
99
2.58
4.51
1.1
1.3
107.3
101.9
u/ml
—
7
17
24
95
2.58
4.34
2.5
1.2
—
—
—
0
0
366
3108
1.39
4.28
5.3
4.8
6.8
6.7
mmol/l
0.49
343
2890
114
777
1.56
4.27
2.1
2.1
—
—
—
0
0
19
67
2.89
4.25
2.3
2.0
30.3
32.4
pg
1.01
19
67
51
282
1.88
4.10
7.3
11.3
—
—
—
0
0
57
327
1.81
4.08
1.7
1.6
1.4
1.6
g/l
0.18
52
301
212
1652
1.42
4.06
2.8
2.5
55.2
56.5
u/l
0.26
201
1528
498
4479
1.44
4.06
21.8
17.0
13.7
13.7
%
0.36
489
4396
60
353
1.77
3.96
2.0
2.5
—
—
—
0
0
51
289
1.83
3.81
3.8
2.6
0.4
0.2
e6/l
0.25
51
280
36
181
2.05
3.81
1.1
1.3
—
—
—
0
0
149
1106
1.45
3.69
1.8
1.7
432.4
18907539.3
pmol/l
1.04
131
915
203
1597
1.39
3.61
3.3
3.1
—
—
—
0
0
219
1775
1.35
3.17
6.8
5.4
—
—
—
0
0
354
3079
1.32
3.13
9.7
8.7
4.2
4.1
e9/l
0.59
324
2709
260
2167
1.33
3.10
11.0
8.5
1.3
1.2
inr
0.69
72
618
435
3905
1.33
3.02
5.4
4.0
13.3
11.9
mm/h
1.09
417
3586
304
2603
1.31
2.95
7.4
6.6
1.2
1.2
mmol/l
0.01
259
2205
23
108
2.17
2.93
1.0
1.3
307.1
263.1
u/ml
0.32
11
60
88
617
1.49
2.90
5.7
8.1
5.1
5.1
kpa
0.12
82
591
64
420
1.58
2.85
2.6
2.8
66.1
67.0
g/l
0.41
58
380
409
3659
1.31
2.81
5.6
4.2
—
—
—
0
0
67
446
1.56
2.81
7.9
6.4
11.2
9.7
mmol/l
0.71
62
423
24
118
2.07
2.75
3.3
4.0
21.1
26.0
mg/l
0.22
17
76
28
146
1.96
2.74
3.0
2.6
25.7
24.9
mmol/l
0.26
21
129
16
66
2.46
2.73
1.4
1.4
—
—
—
0
0
16
66
2.46
2.73
1.4
1.4
—
—
—
0
0
16
66
2.46
2.73
1.4
1.4
—
—
—
0
0
16
66
2.46
2.73
1.4
1.4
—
—
—
0
0
87
618
1.47
2.70
5.7
8.1
11.3
12.3
kpa
1.30
81
596
9
24
3.79
2.68
4.4
5.8
—
—
—
0
0
449
4082
1.31
2.66
9.1
7.4
77.1
78.0
u/l
0.13
430
3825
86
614
1.46
2.60
5.8
8.2
1.8
1.1
mmol/l
0.97
64
488
168
1345
1.33
2.58
2.4
2.1
2.8
3.1
mg/l
0.68
146
1140
393
3522
1.28
2.54
5.3
4.3
861.5
2284.7
e6/l
0.51
17
63
21
102
2.09
2.49
3.9
1.3
—
—
—
0
0
55
363
1.56
2.42
5.1
5.9
—
—
—
0
0
316
2774
1.26
2.35
7.3
6.2
11.4
11.3
umol/l
0.05
302
2619
574
5441
1.40
2.33
19.9
16.2
139.4
139.6
mmol/l
1.30
560
5292
23
119
1.97
2.33
4.4
3.9
—
—
—
0
0
64
441
1.50
2.32
3.0
2.8
74.2
71.7
e9/l
0.19
54
342
129
1009
1.35
2.31
1.9
1.9
—
—
—
0
0
408
3700
1.27
2.28
4.1
3.8
—
—
—
0
0
575
5459
1.39
2.25
20.4
16.3
4.0
4.0
mmol/l
0.79
560
5302
14
60
2.36
2.23
2.9
2.0
13.1
13.1
%
0.12
14
60
5
9
5.59
2.21
1.2
1.3
—
—
—
0
0
28
158
1.81
2.21
4.3
3.8
23.3
48.8
mg/l
0.68
23
121
28
158
1.81
2.21
4.3
3.8
27.5
98.8
mg/l
0.99
23
119
68
483
1.45
2.14
3.9
3.3
1.9
1.9
mmol/l
0.03
53
382
486
4517
1.28
2.13
22.4
17.9
333.8
332.9
g/l
1.42
477
4487
92
691
1.38
2.12
1.3
1.3
292.0
533.0
titre
1.89
20
148
11
44
2.53
2.02
6.2
1.2
—
—
—
0
0
287
2524
1.24
2.01
4.8
4.2
—
—
—
0
0
147
1199
1.29
1.95
1.7
1.7
1.1
1.2
mg/l
0.23
122
906
236
2038
1.24
1.94
4.1
3.7
60.1
51.7
ng/l
0.13
154
1435
11
45
2.47
1.94
1.2
1.1
—
—
—
0
0
95
1214
0.75
1.90
3.7
3.5
—
—
—
0
0
262
2296
1.23
1.87
3.3
2.7
133.8
127.7
ug/l
0.16
239
2117
96
742
1.34
1.87
2.9
2.2
2.3
2.3
g/l
0.07
89
689
8
28
2.88
1.86
1.5
1.1
—
—
—
0
0
110
882
1.30
1.66
1.2
1.3
23.7
33.6
iu/ml
0.52
37
278
20
112
1.81
1.66
4.0
3.7
2.3
2.8
mmol/l
0.36
15
76
20
112
1.81
1.66
1.8
1.7
—
—
—
0
0
19
105
1.83
1.64
3.2
2.6
14.6
16.0
%
0.87
11
55
23
136
1.72
1.60
3.2
2.6
7.7
8.1
kpa
0.51
18
123
8
32
2.52
1.60
1.3
3.6
—
—
—
0
0
132
1090
1.26
1.58
4.0
2.5
3.8
5.8
e6/l
1.20
123
958
24
146
1.67
1.52
1.2
1.2
104.3
69.1
titre
—
7
11
289
2599
1.20
1.51
4.2
3.6
0.0
0.0
estimate
0.00
67
483
15
79
1.92
1.50
1.1
1.2
—
—
—
0
0
185
1597
1.22
1.48
2.8
2.1
217.9
285.8
u/l
0.33
174
1500
106
1291
0.79
1.47
3.4
2.4
—
—
—
0
0
18
102
1.79
1.46
3.4
2.4
—
—
—
0
0
10
46
2.19
1.40
1.1
1.1
—
—
—
0
0
212
1865
1.20
1.39
3.1
2.8
—
—
—
0
0
5
121
0.41
1.38
1.0
1.3
—
—
—
0
0
14
75
1.89
1.35
2.1
2.6
—
—
—
0
0
10
47
2.14
1.34
1.6
1.2
—
—
—
0
0
80
636
1.29
1.31
1.8
1.6
—
—
—
0
0
555
5334
1.24
1.30
18.8
14.2
27.1
24.2
mg/l
1.01
473
4222
287
2606
1.18
1.29
5.7
4.9
0.0
0.0
estimate
0.00
66
487
78
620
1.29
1.29
1.8
1.6
—
—
—
0
0
6
25
2.41
1.24
1.0
1.0
—
0.3
—
0
7
101
833
1.25
1.24
1.1
1.3
8.2
10.6
u/ml
0.14
34
315
289
2637
1.17
1.21
4.2
3.6
0.0
0.0
estimate
0.00
64
463
115
967
1.23
1.19
1.7
1.7
1347.0
1178.9
nmol/l
0.62
95
732
259
2349
1.17
1.16
13.6
9.3
0.0
0.0
e9/l
0.30
219
1941
8
39
2.06
1.15
1.0
1.2
—
—
—
0
0
5
20
2.51
1.15
1.6
1.8
—
—
—
0
0
51
389
1.34
1.14
3.7
3.7
83.6
79.9
ng/l
0.12
45
344
10
51
1.98
1.11
1.1
1.3
—
—
—
0
0
27
185
1.48
1.10
3.8
2.2
4124.0
4840.1
u/l
0.06
13
80
51
392
1.33
1.09
1.6
1.5
—
—
—
0
0
8
41
1.96
1.09
3.0
3.1
—
—
—
0
0
8
41
1.96
1.09
1.1
1.9
—
31.2
—
0
6
185
2069
0.85
1.06
1.8
2.1
—
—
—
0
0
7
33
2.13
1.06
1.3
3.5
—
—
—
0
0
83
684
1.24
1.05
7.5
5.2
1.1
1.0
mmol/l
0.89
78
630
85
703
1.24
1.04
3.1
2.2
18.5
23.4
%
3.20
68
609
184
1639
1.17
1.02
3.4
3.1
7.7
7.8
mmol/l
0.08
164
1361
170
1505
1.17
1.02
3.7
3.2
1218.5
188.5
mg/l
1.08
122
981
5
107
0.46
1.01
1.8
1.4
—
—
—
0
0
5
107
0.46
1.01
1.8
1.4
—
—
—
0
0
10
53
1.90
1.01
3.4
3.2
—
—
—
0
0
5
108
0.46
1.01
1.8
1.5
—
—
—
0
0
15
91
1.66
1.01
1.0
1.0
—
—
—
0
0
92
1090
0.82
1.01
2.4
3.0
0.6
0.8
ug/l
1.89
59
692
16
99
1.63
1.00
4.2
2.5
—
—
—
0
0
122
1051
1.20
1.00
1.5
1.4
2.7
2.5
g/l
0.55
84
646
143
1251
1.18
0.99
1.7
1.5
19.6
20.8
nmol/l
0.53
132
1062
11
61
1.82
0.99
1.3
1.9
—
—
—
0
0
38
498
0.75
0.96
4.3
4.2
—
—
—
0
0
14
85
1.66
0.95
1.1
1.2
2.4
7.3
u/ml
—
5
37
15
93
1.63
0.94
2.8
1.6
—
—
—
0
0
12
70
1.73
0.93
2.7
2.8
—
—
—
0
0
20
134
1.51
0.92
1.3
1.2
—
2.7
—
0
18
95
806
1.21
0.92
3.1
2.2
11.4
13.4
umol/l
2.20
88
747
52
412
1.28
0.92
3.5
2.7
4.6
4.5
kpa
0.05
46
395
6
28
2.15
0.91
1.8
3.6
87.3
94.3
nmol/l
—
6
28
6
28
2.15
0.91
1.0
1.4
123.3
146.0
nmol/l
—
6
28
42
324
1.32
0.90
1.5
1.3
—
35.7
—
0
21
581
5657
1.21
0.90
12.4
10.1
27.9
26.7
u/l
0.52
569
5452
175
1570
1.16
0.89
4.9
3.7
7.4
7.4
ph
0.23
43
287
6
30
2.01
0.87
1.0
1.3
—
—
—
0
0
419
3987
1.14
0.87
4.4
3.8
14.6
14.8
pmol/l
0.67
395
3589
15
227
0.65
0.86
1.0
1.1
—
—
—
0
0
17
112
1.53
0.85
4.5
3.0
—
—
—
0
0
232
2129
1.14
0.85
2.1
2.0
100.1
95.7
pmol/l
0.60
131
1101
10
57
1.77
0.84
2.2
2.6
—
—
—
0
0
6
114
0.52
0.83
1.3
1.5
—
—
—
0
0
8
46
1.75
0.82
1.3
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
—
—
0
0
15
98
1.54
0.79
4.1
3.6
57.1
57.9
%
0.07
15
98
73
617
1.21
0.76
2.8
2.8
6.6
8.7
umol/l
0.95
62
536
9
53
1.71
0.75
1.0
1.2
—
—
—
0
0
65
544
1.22
0.75
3.3
4.4
10.6
33.9
ug/l
0.79
48
463
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
5
24
2.09
0.74
1.0
1.5
—
—
—
0
0
116
1309
0.86
0.74
8.8
6.7
—
—
—
0
0
34
434
0.77
0.74
3.9
3.2
—
—
—
0
0
50
407
1.25
0.74
1.2
1.2
—
—
—
0
0
5
25
2.01
0.73
1.0
1.0
—
0.4
—
0
5
9
58
1.56
0.70
1.9
2.3
—
—
—
0
0
190
1744
1.13
0.68
3.6
3.3
2.4
2.4
mmol/l
0.05
171
1527
7
117
0.59
0.68
1.9
2.0
—
—
—
0
0
149
1348
1.14
0.68
3.4
2.6
2682.0
6576.8
umol/l
0.83
137
1159
167
1522
1.13
0.68
3.2
3.0
1560.7
1280.2
ng/l
0.32
146
1297
54
449
1.22
0.67
6.2
3.7
—
—
—
0
0
29
223
1.31
0.67
1.9
2.1
1.3
1.5
g/l
0.46
19
199
14
94
1.50
0.67
4.0
3.1
3.2
4.4
e9/l
2.43
14
94
16
225
0.70
0.66
4.2
3.9
25.9
24.9
mmol/l
0.64
16
211
5
28
1.79
0.66
1.6
2.3
—
—
—
0
0
15
103
1.47
0.65
1.0
1.0
—
—
—
0
0
10
62
1.62
0.65
1.3
1.3
—
—
—
0
0
11
166
0.66
0.65
24.8
10.5
—
—
—
0
0
174
1597
1.12
0.63
4.2
4.0
8.7
10.0
mg/mmol
0.16
121
1017
11
71
1.56
0.62
1.3
1.5
—
—
—
0
0
132
1192
1.13
0.62
1.2
1.2
1.0
1.5
u/ml
0.60
33
329
8
49
1.64
0.62
2.1
2.5
—
—
—
0
0
132
1193
1.13
0.61
3.9
3.8
1.0
1.0
kg/l
0.02
26
173
604
5937
1.19
0.61
26.1
20.5
247.9
247.4
e9/l
0.06
590
5790
129
1424
0.88
0.61
3.9
2.9
—
—
—
0
0
14
198
0.70
0.61
2.6
4.1
1.5
1.3
mmol/l
0.34
14
191
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
527
5135
1.13
0.60
4.4
4.4
5.9
6.0
mmol/l
0.08
496
4667
604
5940
1.18
0.59
25.9
20.5
90.9
90.9
fl
0.01
595
5854
63
729
0.85
0.58
1.4
1.2
—
—
—
0
0
51
430
1.20
0.57
6.0
7.8
—
—
—
0
0
18
132
1.37
0.57
2.0
1.8
5.1
5.2
iu/l
—
8
41
604
5942
1.18
0.57
26.0
20.5
4.5
4.5
e12/l
1.08
591
5776
604
5942
1.18
0.57
25.9
20.4
30.3
30.3
pg
0.06
595
5855
604
5942
1.18
0.57
26.1
20.6
6.7
6.7
e9/l
0.08
591
5773
95
846
1.14
0.56
4.8
3.1
0.8
0.8
mmol/l
0.34
88
795
604
5945
1.17
0.55
26.1
20.6
135.0
135.9
g/l
0.73
595
5854
15
203
0.73
0.52
2.9
3.0
0.6
0.2
g/l
—
6
79
9
132
0.68
0.52
1.2
1.1
—
—
—
0
0
58
501
1.17
0.51
1.4
1.5
—
—
—
0
0
56
645
0.86
0.50
1.2
1.3
—
—
—
0
0
20
154
1.31
0.49
3.6
3.1
—
—
—
0
0
93
838
1.13
0.47
1.7
1.6
—
—
—
0
0
5
84
0.59
0.45
1.0
1.1
—
—
—
0
0
5
85
0.59
0.45
1.0
1.1
—
—
—
0
0
75
669
1.14
0.45
15.3
22.2
1.2
1.3
inr
0.21
23
90
17
219
0.77
0.44
2.2
1.8
—
—
—
0
0
6
95
0.63
0.42
2.5
1.6
64.8
62.1
%
—
6
95
566
5567
1.11
0.42
18.3
13.2
—
—
—
0
0
13
96
1.36
0.42
3.8
1.9
—
—
—
0
0
32
268
1.20
0.41
2.6
2.4
—
—
—
0
0
8
58
1.38
0.41
1.4
1.3
—
—
—
0
0
35
296
1.19
0.41
1.2
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
2.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
148
1381
1.09
0.40
1.8
1.6
1.5
1.4
mmol/l
0.39
128
1160
249
2375
1.08
0.40
6.4
5.8
1.2
1.2
mmol/l
0.16
230
2142
527
5170
1.09
0.40
4.3
4.3
1.4
1.4
mmol/l
0.38
501
4757
8
61
1.32
0.39
1.4
1.2
—
—
—
0
0
8
61
1.32
0.39
1.0
1.1
—
—
—
0
0
9
66
1.37
0.38
5.7
4.4
—
—
—
0
0
493
4829
1.08
0.37
5.2
4.5
1.9
2.1
mu/l
0.47
468
4389
29
342
0.84
0.36
2.3
2.7
—
—
—
0
0
507
4973
1.08
0.36
3.9
3.9
1.3
1.3
mmol/l
0.24
478
4560
529
5198
1.09
0.36
4.5
4.3
4.6
4.6
mmol/l
0.02
503
4814
159
1685
0.93
0.35
3.0
2.5
—
—
—
0
0
39
339
1.16
0.35
1.2
1.2
—
—
—
0
0
6
43
1.40
0.35
2.8
1.6
1.1
1.2
promille
—
6
31
111
1031
1.09
0.34
3.2
2.8
543.4
563.7
mosm/kgh2o
0.36
101
875
42
368
1.15
0.34
3.4
3.4
5.4
5.2
kpa
0.56
36
342
6
44
1.37
0.34
1.0
1.3
—
—
—
0
0
60
665
0.89
0.34
2.3
2.3
174.8
124.4
ug/g
0.31
53
532
172
1629
1.08
0.33
4.1
3.1
31.4
105.5
e6/l
1.10
150
1238
41
360
1.15
0.33
2.5
2.6
5.0
4.1
e9/l
1.22
32
284
498
4892
1.07
0.31
19.1
14.8
39.3
40.1
%
0.92
316
3534
13
163
0.79
0.29
1.2
1.2
—
—
—
0
0
10
76
1.32
0.28
1.3
1.2
—
—
—
0
0
18
149
1.21
0.28
3.7
4.6
—
—
—
0
0
196
1880
1.06
0.27
4.3
3.6
51.2
111.9
e6/l
1.22
160
1315
92
982
0.93
0.26
2.5
3.0
2.5
2.4
mmol/l
0.85
82
864
14
114
1.23
0.25
2.9
2.6
—
—
—
0
0
140
1470
0.94
0.25
3.8
3.0
0.1
0.5
e6/l
5.47
115
1084
6
84
0.71
0.24
2.2
1.4
—
—
—
0
0
23
264
0.87
0.23
3.7
3.6
—
—
—
0
0
22
253
0.87
0.23
1.1
1.1
—
110.2
—
0
6
195
1881
1.05
0.22
4.9
4.8
2.0
2.6
ug/l
1.29
180
1684
5
41
1.22
0.22
1.4
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
17.0
—
0
10
40
364
1.11
0.21
3.5
3.4
7.4
7.4
ph
—
8
47
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
3.4
—
—
—
0
0
6
50
1.20
0.19
4.0
1.4
—
—
—
0
0
6
50
1.20
0.19
10.3
1.4
—
—
—
0
0
54
501
1.08
0.19
2.8
2.4
0.2
0.2
g/l
0.23
49
469
40
436
0.91
0.19
1.4
1.4
—
—
—
0
0
7
58
1.21
0.18
2.0
1.8
—
—
—
0
0
536
5307
1.05
0.18
4.9
4.8
2.8
2.7
mmol/l
0.26
505
4876
10
120
0.83
0.16
1.0
1.3
—
—
—
0
0
8
72
1.11
0.16
1.3
1.4
32.3
32.8
g/l
—
8
62
17
193
0.88
0.16
1.5
1.6
—
—
—
0
0
6
79
0.76
0.15
1.0
1.0
—
7.0
—
0
44
29
266
1.09
0.14
3.4
3.8
—
—
—
0
0
27
247
1.10
0.13
3.3
2.2
0.7
0.7
%
0.28
27
239
22
199
1.11
0.13
1.1
1.1
—
—
—
0
0
13
113
1.15
0.13
1.2
1.2
—
—
—
0
0
37
345
1.08
0.13
1.4
1.2
273.6
163.1
iu/ml
0.51
12
136
153
1492
1.03
0.11
1.4
1.5
—
—
—
0
0
490
4860
1.03
0.11
5.9
5.7
40.6
39.9
mmol/mol
0.81
467
4517
29
311
0.93
0.10
1.7
1.4
—
—
—
0
0
49
515
0.95
0.10
1.5
1.4
—
—
—
0
0
148
1516
0.97
0.10
4.5
4.0
—
—
—
0
0
19
174
1.09
0.09
3.9
1.6
—
—
—
0
0
57
593
0.96
0.09
1.2
1.3
—
—
—
0
0
49
511
0.96
0.08
1.4
1.3
—
—
—
0
0
16
146
1.10
0.08
4.8
2.1
—
—
—
0
0
5
65
0.77
0.08
1.2
1.3
0.5
0.5
nmol/l
—
5
59
6
74
0.81
0.07
1.0
1.0
—
1.0
—
0
32
9
84
1.07
0.07
1.6
1.6
—
—
—
0
0
9
84
1.07
0.07
1.6
2.2
5.7
52.2
u/ml
—
9
79
66
643
1.03
0.05
1.6
1.4
—
—
—
0
0
14
150
0.93
0.04
1.3
1.2
—
—
—
0
0
37
382
0.97
0.04
1.5
1.4
—
—
—
0
0
60
587
1.02
0.04
1.4
1.7
—
—
—
0
0
21
220
0.95
0.03
5.0
1.5
—
—
—
0
0
141
1425
0.99
0.03
5.0
3.8
0.0
0.0
estimate
0.69
65
471
21
219
0.96
0.03
3.6
1.5
—
—
—
0
0
20
208
0.96
0.02
3.1
2.7
—
—
—
0
0
21
218
0.96
0.02
3.7
1.5
—
—
—
0
0
21
217
0.97
0.01
3.7
1.6
—
—
—
0
0
14
146
0.96
0.00
3.4
2.4
60.0
63.6
ug/min
—
9
86
11
115
0.96
0.00
1.1
1.3
—
—
—
0
0
20
204
0.98
0.00
4.9
4.4
—
—
—
0
0
22
216
1.02
0.00
1.4
3.3
19.6
6505.2
u/ml
0.79
17
185
23
234
0.98
0.00
1.7
1.7
—
—
—
0
0
20
203
0.98
0.00
3.7
1.6
—
—
—
0
0
21
212
0.99
0.00
1.3
1.2
—
—
—
0
0
7
78
0.90
0.00
1.1
1.2
—
—
—
0
0
5
57
0.88
0.00
1.6
1.6
—
—
—
0
0
5
55
0.91
0.00
1.0
1.4
266.2
279.7
mosm/kgh2o
—
5
43
7
77
0.91
0.00
3.0
2.7
107.6
105.4
mmol/l
—
7
77
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
55
550
1.00
0.00
1.7
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
9
95
0.95
0.00
1.1
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
7
77
0.91
0.00
3.0
2.7
4.1
4.0
mmol/l
—
7
77
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
0.00
3.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_ZOONOTIC_BACTERIAL and mortality.

Females

Parameter HR [95% CI] p-value
AB1_ZOONOTIC_BACTERIAL 1.32 [1.11, 1.57] 0.002
Birth year 0.998 [0.99, 1.01] 0.644

During the follow-up period (1.1.1998 — 31.12.2019), 303 out of 1976 females with AB1_ZOONOTIC_BACTERIAL died.

Males

Parameter HR [95% CI] p-value
AB1_ZOONOTIC_BACTERIAL 1.111 [0.96, 1.29] 0.16
Birth year 0.988 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 369 out of 2439 males with AB1_ZOONOTIC_BACTERIAL died.

Mortality risk

Mortality risk for people of age

years, who have AB1_ZOONOTIC_BACTERIAL.

N-year risk Females Males
1 0.128% 0.284%
5 0.806% 1.415%
10 2.18% 3.598%
15 4.413% 6.727%
20 7.549% 11.22%

Relationships between endpoints

↥

Index endpoint: AB1_ZOONOTIC_BACTERIAL – Certain zoonotic bacterial diseases

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data