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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Erysipeloid

AB1_ERYSIPLEOID

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A26
  • Hospital discharge: ICD-9 027[1]
  • Hospital discharge: ICD-8 027[1]
  • Cause of death: ICD-10 A26
  • Cause of death: ICD-9 027[1]
  • Cause of death: ICD-8 027[1]

2 out of 7 registries used, show all original rules.

45

4. Check minimum number of events

None

45

5. Include endpoints

None

45

6. Filter based on genotype QC (FinnGen only)

45

Control definitions (FinnGen only)

Control exclude
AB1_ZOONOTIC_BACTERIAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 563 251 308
Only index persons 422 186 236
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 57.27 60.29 54.59
Only index persons 52.29 54.42 50.61

-FinnGen-

Key figures

All Female Male
Number of individuals 45 19 26
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 63.75 65.36 62.57

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6
12
5.58
2.49
2.3
1.1
—
—
—
0
0
6
13
5.14
2.35
4.8
2.6
25.6
25.4
mmol/l
—
6
13
6
15
4.44
2.11
4.8
2.1
—
—
—
0
0
5
12
4.54
1.87
1.4
1.1
—
—
—
0
0
11
54
2.37
1.47
1.4
1.3
3.8
2.7
g/l
—
6
29
17
248
0.49
1.41
4.8
4.0
—
—
—
0
0
18
115
1.94
1.25
4.3
4.8
—
—
—
0
0
6
26
2.50
1.23
1.5
1.4
—
—
—
0
0
8
39
2.27
1.23
2.0
1.4
—
—
—
0
0
6
32
2.01
0.85
3.5
3.3
—
—
—
0
0
16
110
1.71
0.83
7.1
4.2
—
—
—
0
0
17
119
1.69
0.83
6.0
4.2
—
—
—
0
0
9
58
1.69
0.75
2.9
1.9
—
—
—
0
0
7
44
1.70
0.69
1.0
1.3
—
—
—
0
0
5
28
1.88
0.68
4.2
8.7
—
—
—
0
0
0
19
0.00
0.62
0.0
3.2
—
—
—
0
0
0
21
0.00
0.62
0.0
2.6
—
0.1
—
0
7
21
165
1.51
0.61
14.0
7.1
1.5
1.3
inr
—
6
48
0
23
0.00
0.60
0.0
1.7
—
—
—
0
0
20
156
1.51
0.60
6.4
6.3
1.2
1.2
mmol/l
1.40
20
141
32
357
0.64
0.56
28.7
18.0
96.2
84.7
umol/l
0.36
32
357
5
83
0.55
0.51
10.6
2.8
3.0
3.8
e6/l
—
5
76
5
32
1.63
0.44
4.0
4.1
6.2
5.6
kpa
—
5
32
5
32
1.63
0.44
4.0
4.2
4.2
2.0
mmol/l
—
5
24
0
15
0.00
0.42
0.0
5.3
—
—
—
0
0
0
16
0.00
0.42
0.0
1.1
—
—
—
0
0
32
351
0.69
0.41
27.3
14.9
—
—
—
0
0
8
105
0.71
0.34
7.1
3.1
—
—
—
0
0
21
241
0.76
0.33
9.2
4.9
—
1322.7
—
0
6
15
122
1.34
0.32
7.7
3.1
—
—
—
0
0
7
55
1.32
0.32
2.3
1.7
—
—
—
0
0
14
113
1.35
0.32
2.7
2.4
—
—
—
0
0
5
73
0.65
0.28
19.4
5.1
—
—
—
0
0
19
163
1.29
0.28
7.5
4.6
0.7
0.6
%
0.53
19
152
24
216
1.24
0.22
5.0
4.5
6.9
6.8
mmol/l
0.04
24
198
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
4.6
—
1.5
—
0
10
0
10
0.00
0.21
0.0
4.6
—
7.8
—
0
10
0
12
0.00
0.21
0.0
13.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
4.2
—
0.9
—
0
13
0
13
0.00
0.21
0.0
3.9
—
1.8
—
0
13
6
50
1.23
0.21
2.3
1.5
—
—
—
0
0
19
169
1.22
0.19
7.5
4.9
3.5
2.7
%
0.80
19
157
19
169
1.22
0.19
7.6
5.4
9.5
8.6
%
0.57
19
158
13
150
0.81
0.18
4.2
3.9
—
—
—
0
0
19
170
1.20
0.17
6.5
4.8
59.3
59.1
%
0.03
19
158
7
86
0.78
0.16
1.3
1.4
—
—
—
0
0
7
88
0.76
0.16
8.1
3.4
679.6
563.4
mosm/kgh2o
—
7
77
24
257
0.86
0.13
8.2
4.6
—
—
—
0
0
19
174
1.16
0.12
7.6
5.0
24.1
25.9
%
0.37
19
160
28
295
0.87
0.11
22.2
17.1
40.8
38.4
%
1.34
15
201
5
43
1.18
0.10
1.6
1.3
—
—
—
0
0
5
46
1.10
0.10
1.4
1.2
—
—
—
0
0
20
186
1.14
0.09
11.2
5.7
10.9
10.5
umol/l
0.07
20
176
9
101
0.86
0.07
3.0
3.2
—
—
—
0
0
10
108
0.90
0.03
8.5
4.0
—
—
—
0
0
17
163
1.07
0.02
2.3
2.0
103.1
93.3
pmol/l
0.55
11
86
14
138
1.02
0.00
2.6
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
5.0
—
10.2
—
0
6
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
0.00
0.0
3.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
7
70
1.00
0.00
3.3
1.9
2.3
2.4
g/l
—
7
62
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
3.7
—
106.3
—
0
8
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
3.7
—
4.0
—
0
8
9
97
0.91
0.00
6.3
6.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
5.0
—
104.0
—
0
6
34
340
1.00
0.00
3.9
5.1
2.6
2.5
mmol/l
0.16
29
303
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_ERYSIPLEOID and mortality.

Females

Parameter HR [95% CI] p-value
AB1_ERYSIPLEOID 1.806 [1.27, 2.56] < 0.001
Birth year 0.997 [0.99, 1.01] 0.492

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 178 females with AB1_ERYSIPLEOID died.

Males

Parameter HR [95% CI] p-value
AB1_ERYSIPLEOID 1.795 [1.22, 2.63] 0.003
Birth year 0.988 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 221 males with AB1_ERYSIPLEOID died.

Mortality risk

Mortality risk for people of age

years, who have AB1_ERYSIPLEOID.

N-year risk Females Males
1 0.138% 0.419%
5 1.163% 2.418%
10 2.884% 5.615%
15 5.718% 10.692%
20 10.07% 17.666%

Relationships between endpoints

Index endpoint: AB1_ERYSIPLEOID – Erysipeloid

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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