Heart failure and hypertrophic cardiomyopathy

I9_HEARTFAIL_AND_HYPERTCARDIOM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

  • I9_HYPERTROCARDMYOP
1583

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

646

6. Filter based on genotype QC (FinnGen only)

622

Control definitions (FinnGen only)

Control conditions
not I9_HYPERTROCARDMYOP

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3880 1606 2239
Only index persons 3162 1299 1863
Unadjusted period prevalence (%)
Whole population 0.06 0.05 0.06
Only index persons 0.06 0.05 0.07
Median age at first event (years)
Whole population 64.57 67.92 62.15
Only index persons 64.98 68.74 62.35

-FinnGen-

Key figures

All Female Male
Number of individuals 622 235 387
Unadjusted period prevalence (%) 0.14 0.08 0.18
Median age at first event (years) 62.08 64.04 60.89

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
646
Matched controls
6460
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
201
Kela drug reimbursment
Chronic cardiac insufficiency
22.3
321.9
288
225
I42.1
ICD-10 Finland
Obstructive hypertrophic cardiomyopathy
+∞
307.7
309
*
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
69.5
307.7
181
36
I42.0
ICD-10 Finland
Dilated cardiomyopathy
50.3
307.7
270
91
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
8914.3
307.7
468
*
I50.9
ICD-10 Finland
Heart failure, unspecified
30.7
307.7
521
772
C03DA01
ATC
spironolactone; oral
14.8
276.6
379
565
I50.0
ICD-10 Finland
Congestive heart failure
14.8
254.9
301
360
I50.1
ICD-10 Finland
Left ventricular failure
16.2
235.8
241
229
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
13.7
224.9
266
314
C03CA01
ATC
furosemide; systemic
21.8
218.6
577
1792
C01BD01
ATC
amiodarone; systemic
23.8
216.6
168
94
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
14.3
210.8
231
242
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
9.3
184.0
393
923
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
33.8
167.4
110
39
I47.2
ICD-10 Finland
Ventricular tachycardia
24.3
164.4
123
62
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
96.4
160.7
84
10
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
13.4
158.7
170
168
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
8.2
157.3
428
1245
B01AA03
ATC
warfarin; systemic
8.0
157.3
400
1089
I48
ICD-10 Finland
Atrial fibrillation and flutter
7.9
151.2
430
1294
207
Kela drug reimbursment
Chronic arrhythmias
7.3
142.4
338
845
TFP20
NOMESCO Finland
Cardiodefibrillation
7.5
108.8
190
339
C07AB07
ATC
bisoprolol; oral
10.5
106.6
575
2814
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.8
105.8
294
814
XF404
NOMESCO Finland
Ambulatory ECG
7.0
102.6
194
374
GD1LA
NOMESCO Finland
GD
19.7
96.2
77
44
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
24.0
94.3
69
32
C01AA05
ATC
digoxin; systemic
6.4
92.7
192
402
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
24.4
90.8
66
30
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
7.6
90.5
148
243
C09DX04
ATC
valsartan and sacubitril; oral
23.6
89.6
66
31
AN1
HP
Coronary angiography
5.5
86.2
222
563
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
36.7
85.6
54
16
FPG30
NOMESCO Finland
Implantation of cardioverter-defibrillator with ventricular electrode
35.3
81.5
52
16
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
21.9
79.2
60
30
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.3
73.9
322
1211
FPG96
NOMESCO Finland
Other implantation of permanent cardioverter-defibrillator
35.3
72.2
46
14
C09AA05
ATC
ramipril; oral
4.2
71.5
353
1442
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
6.2
66.9
130
251
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
4.2
66.9
260
889
I44.2
ICD-10 Finland
Atrioventricular block, complete
8.7
66.2
90
118
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.4
64.6
479
2535
127
Kela drug reimbursment
Transplant complication
16.9
62.1
53
34
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
6.8
61.6
107
184
250, ,
Kela drug reimbursment
17.0
61.3
52
33
L04AD02
ATC
tacrolimus; systemic
29.1
60.6
41
15
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
4.1
60.1
232
781
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
12.6
59.3
60
52
L04AA06
ATC
mycophenolic acid; systemic
14.0
56.0
53
41
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
6.9
55.9
94
156
I50
ICD-10 Finland
Heart failure
7.5
55.3
85
128
M04AA01
ATC
allopurinol; systemic
4.0
53.9
202
660
XF400
NOMESCO Finland
ECG with 12 standard connections
3.9
53.7
220
764
B01AF02
ATC
apixaban; oral
4.0
51.8
187
593
TK800
NOMESCO Finland
Hemodialysis
10.9
51.1
57
57
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
11.3
50.6
55
53
C07AA07
ATC
sotalol; systemic
6.2
47.4
87
157
Z94.1
ICD-10 Finland
Heart transplant status
92.2
46.6
51
6
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
5.8
46.3
93
183
R06.0
ICD-10 Finland
Dyspnoea
3.2
45.9
292
1315
WX892
NOMESCO Finland
Monitored bed care
4.8
45.7
119
293
Z2221
NOMESCO Finland
Medical doctor
3.3
45.4
269
1161
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
10.8
44.8
50
50
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
7.2
43.8
69
106
I48.2
ICD-10 Finland
Chronic atrial fibrillation
5.5
43.6
92
189
ZXD05
NOMESCO Finland
Urgent procedure
3.1
42.4
285
1313
XF640, ,
NOMESCO Finland
7.5
41.8
63
92
I49.0
ICD-10 Finland
Ventricular fibrillation and flutter
13.3
41.3
40
32
G04BE03
ATC
sildenafil; oral
10.3
40.8
47
49
ZX120
NOMESCO Finland
Intravenous
4.1
40.1
126
357
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
4.0
39.6
134
400
TPH04
NOMESCO Finland
Cathetrisation of vein
3.1
39.3
233
991
I49.5
ICD-10 Finland
Sick sinus syndrome
5.5
38.6
80
161
Z3231
NOMESCO Finland
Registered nurse
3.0
38.6
271
1265
R4110
NOMESCO Finland
Physiotherapy
3.0
38.4
265
1224
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
141.9
38.2
40
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
4.2
37.1
112
307
A12BA01
ATC
potassium chloride; oral
5.0
36.6
85
189
WX872
NOMESCO Finland
Intensive care
4.9
36.0
86
196
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.2
35.7
177
674
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.6
34.9
139
461
TPH07
NOMESCO Finland
Cathetrisation of artery
3.5
34.3
143
488
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
33.9
275
1365
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
4.7
33.5
84
199
I42
ICD-10 Finland
Cardiomyopathy
+∞
32.6
31
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
32.5
214
950
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.0
32.1
73
159
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.8
31.3
109
329
81
HP
Angiography of the heart and coronary arteries
3.8
31.2
107
320
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
4.8
31.0
74
168
WX740
NOMESCO Finland
Nitrogen oxide therapy
115.7
31.0
33
*
K77
ICPC
Heart failure
6.7
30.9
51
82
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.6
30.6
263
1331
A10BK01
ATC
dapagliflozin; oral
4.1
30.2
93
257
I48.1
ICD-10 Finland
Persistent atrial fibrillation
4.8
29.5
70
158
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.6
28.6
106
333
ZXD10
NOMESCO Finland
Scheduled procedure
2.5
28.6
317
1795
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.1
28.6
85
229
C07AG02
ATC
carvedilol; oral
3.9
28.5
93
268
K78
ICPC
Atrial fibrillation/flutter
3.4
28.5
117
393
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
57.8
28.4
33
6
4251A
ICD-9 Finland
Cardiomyopathy, Hypertrophic obstructive cardiomyopathy
+∞
28.3
27
*
XFE00
NOMESCO Finland
Epicardial ultrasonography
6.7
28.2
46
73
ZXE00
NOMESCO Finland
One hour or less
2.5
27.8
311
1761
M10.9
ICD-10 Finland
Gout, unspecified
3.7
27.6
97
294
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
5.0
27.4
62
134
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
6.8
27.2
44
69
XF402
NOMESCO Finland
ECG with work load test
3.1
27.0
131
486
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.0
26.3
136
522
K84
ICPC
Heart disease other
5.7
26.3
51
96
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
5.6
26.2
52
100
I42.8
ICD-10 Finland
Other cardiomyopathies
60.6
25.2
29
5
TK810
NOMESCO Finland
Hemofiltration
27.5
25.1
34
13
FPG40
NOMESCO Finland
Replacement of pulse generator in transvenous cardioverter-defibrillator
93.8
24.8
27
*
1CX08, ,
NOMESCO Finland
44.8
24.8
30
7
N18.8
ICD-10 Finland
Other chronic renal failure
6.2
24.6
43
73
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
25.6
24.6
34
14
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
5.5
24.5
49
95
TFJ02
NOMESCO Finland
Muscle biopsy of heart
43.3
23.8
29
7
ZXE40
NOMESCO Finland
More than seven and less than nine hours
6.8
23.7
38
59
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.4
23.7
62
151
Z3226
NOMESCO Finland
Physiotherapist
2.6
23.5
168
761
C07AB02
ATC
metoprolol; systemic
2.5
23.4
208
1045
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.3
23.2
40
67
TFP35
NOMESCO Finland
Electroanatomical mapping
8.3
23.2
31
39
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
22.5
291
1714
TFP34
NOMESCO Finland
Electrophysiological investigation
5.4
22.5
46
91
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.7
22.4
76
224
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.0
21.9
65
174
AS4
HP
Physiological pacemaker insertion DDD (R)
7.4
21.8
32
45
7AX01, ,
NOMESCO Finland
227.4
21.7
22
*
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
45.0
21.6
26
6
R02
ICPC
Shortness of breath/dyspnoea
2.8
21.0
127
527
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
8.1
20.6
28
36
A46
ICD-10 Finland
Erysipelas
2.6
20.5
146
656
AP4
HP
Myocardial biopsy
33.8
20.3
26
8
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
4.3
20.3
54
133
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.2
20.1
251
1442
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.9
19.7
61
168
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
6.4
19.6
33
54
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.7
19.5
37
68
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
6.7
19.4
31
48
R55
ICD-10 Finland
Syncope and collapse
2.7
19.2
120
505
AA1AD
NOMESCO Finland
CT of head and brain
2.2
18.9
242
1397
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
8.3
18.9
25
31
I43.1*E85.9
ICD-10 Finland
Cardiac amyloidosis
+∞
18.8
18
*
AP1
HP
Catheterization of the left side of the heart
6.3
18.7
32
53
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
18.7
80
273
D64.9
ICD-10 Finland
Anaemia, unspecified
2.7
18.6
115
481
H02AB06
ATC
prednisolone; systemic
2.1
18.4
352
2356
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
7.4
18.4
27
38
3AC01, ,
NOMESCO Finland
20.1
18.3
27
14
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.2
18.3
51
130
H03BB01
ATC
carbimazole; oral
4.9
18.2
41
88
ZX108
NOMESCO Finland
Inhalation
15.9
18.1
29
19
3A064, ,
NOMESCO Finland
34.0
18.1
23
7
I47.1
ICD-10 Finland
Supraventricular tachycardia
4.2
17.6
49
125
A10BK03
ATC
empagliflozin; oral
2.7
17.3
103
421
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.6
17.3
118
517
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
17.2
234
1373
A11CC03
ATC
alfacalcidol; systemic
5.3
17.1
35
69
I45.9
ICD-10 Finland
Conduction disorder, unspecified
7.8
17.1
24
32
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
17.0
204
1140
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.4
16.8
64
203
A10BH05
ATC
linagliptin; oral
3.3
16.6
67
220
205
Kela drug reimbursment
Chronic hypertension
2.1
16.6
248
1502
FXL00
NOMESCO Finland
Insertion and use of extra-, para- or intracorporeal VAD
174.3
16.6
17
*
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
5.9
16.5
30
53
Z2446
NOMESCO Finland
Social worker
3.2
16.5
69
232
AS8
HP
Physiological arrhythmia pacemaker insertionDDD (R) S
30.9
16.2
21
7
XF600
NOMESCO Finland
Bloodpressure measurement
3.2
16.1
68
230
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
6.4
16.0
27
44
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.9
16.0
48
129
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
15.0
16.0
26
18
C01DA14
ATC
isosorbide mononitrate; oral
2.2
16.0
172
918
742, ,
NOMESCO Finland
61.6
15.8
18
*
AP3
HP
Catheterization of the right and left side of the heart
34.3
15.8
20
6
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.1
15.7
71
250
B01AB05
ATC
enoxaparin; parenteral
2.0
15.4
248
1534
FPE37
NOMESCO Finland
Implantation of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
24.1
15.2
21
9
AP2
HP
Catheterization of the right side of the heart
24.1
15.2
21
9
AS7
HP
Arrhythmia pacemaker insertion VVI (R) S
46.2
15.1
18
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.9
15.0
74
273
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
14.9
79
303
71
HP
Electrophysiological Special Examination
17.0
14.9
23
14
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
14.8
124
594
C10AA01
ATC
simvastatin; oral
1.9
14.7
357
2524
N19
ICD-10 Finland
Unspecified kidney failure
3.6
14.7
51
152
AK1
HP
HTX (heart transplant)
+∞
14.6
14
*
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
14.6
232
1423
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.7
14.4
47
134
73
HP
Initial pacemaker installation
13.8
14.3
24
18
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.5
14.3
97
422
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.6
14.3
49
145
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.1
14.2
184
1048
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
14.2
215
1295
M10
ICD-10 Finland
Gout
3.5
14.1
51
156
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
6.0
14.1
25
43
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
5.9
13.8
25
44
C08DA01
ATC
verapamil; systemic
3.3
13.7
54
175
ARB
HP
Catheter ablation of arrhythmia: Cutiing or modification of the AV node
76.8
13.6
15
*
L04AD01
ATC
ciclosporin; systemic
6.0
13.6
24
41
FPJ22
NOMESCO Finland
Revision of cardioverter-defibrillator with atrial and ventricular electrodes
34.8
13.6
17
5
FPJ24
NOMESCO Finland
Revision of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
34.8
13.6
17
5
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.6
13.4
45
131
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.6
13.4
45
131
I20.00
ICD-10 Finland
Unstable angina
3.7
13.3
43
122
PD5BD
NOMESCO Finland
Extensive CT of aorta
5.3
13.3
27
53
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
41.0
13.2
16
*
C01BA03
ATC
disopyramide; systemic
11.3
13.1
24
22
C03AA03
ATC
hydrochlorothiazide; oral
2.5
13.1
89
387
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.0
13.1
38
100
I25.2
ICD-10 Finland
Old myocardial infarction
2.6
13.0
81
337
ATX
HP
Other pacemaker replacement or related action, such as cord removal or replacement
29.0
13.0
17
6
J94.8
ICD-10 Finland
Other specified pleural conditions
5.8
13.0
24
43
E66.8
ICD-10 Finland
Other obesity
3.9
12.9
38
101
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
11.9
12.9
23
20
I42.5
ICD-10 Finland
Other restrictive cardiomyopathy
51.1
12.9
15
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.4
12.8
93
417
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.4
12.7
47
146
R04.0
ICD-10 Finland
Epistaxis
2.6
12.6
76
311
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
12.6
145
786
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.0
12.6
56
195
I44.7
ICD-10 Finland
Left bundle-branch block, unspecified
5.2
12.5
26
52
L28
ICPC
Limited function/disability (L)
2.1
12.5
153
849
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.0
12.5
58
207
A10AB05
ATC
insulin aspart; parenteral
2.6
12.4
74
302
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.3
12.3
106
512
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.3
12.2
108
527
WX002
NOMESCO Finland
Sedation and analgesia
2.0
12.1
153
857
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
8.9
12.1
25
29
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
11.9
217
1374
FM1DM
NOMESCO Finland
Heart very extensive MRI examination with 3 Tesla magnet
47.6
11.9
14
*
XF622
NOMESCO Finland
Measurement of minute volume of heart
47.6
11.9
14
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
11.9
144
794
C09AA02
ATC
enalapril; systemic
2.0
11.9
169
987
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
6.0
11.9
21
36
E05.89
ICD-10 Finland
Other thyrotoxicosis
30.7
11.7
15
5
E85.9
ICD-10 Finland
Amyloidosis, unspecified
66.2
11.6
13
*
R03BB04
ATC
tiotropium bromide; inhalant
2.3
11.6
99
475
R00.1
ICD-10 Finland
Bradycardia, unspecified
3.3
11.6
45
144
R18
ICD-10 Finland
Ascites
4.7
11.5
27
60
42500
ICD-8 Finland
Cardiomyopathy, Stenosis subaortae hypertrophicans
+∞
11.5
11
*
C09AA04
ATC
perindopril; oral
2.9
11.3
55
201
E87.5
ICD-10 Finland
Hyperkalaemia
4.6
11.3
27
61
R53
ICD-10 Finland
Malaise and fatigue
1.9
11.3
177
1066
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.3
11.2
29
70
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.0
11.2
51
180
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
11.1
244
1632
B01AE07
ATC
dabigatran etexilate; oral
3.4
11.0
41
128
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.3
11.0
95
459
ASB
HP
Insertion of a biventricular physiological pacemaker DDD (R)
44.1
11.0
13
*
A41.9
ICD-10 Finland
Sepsis, unspecified
3.3
10.9
42
134
TFP32
NOMESCO Finland
Cathetric treatmen of cardiac arrythmia
18.2
10.8
16
9
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.5
10.8
68
285
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
5.7
10.8
20
36
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
21.9
10.7
15
7
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
13.2
10.7
18
14
JN4AD
NOMESCO Finland
Body CT examination
2.3
10.6
90
431
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.0
10.5
30
78
FXM00
NOMESCO Finland
Removal of extra-, para- or intracorporeal VAD
111.8
10.4
11
*
TK830
NOMESCO Finland
Ultrafiltration
111.8
10.4
11
*
FPE40
NOMESCO Finland
Replacement of transvenous cardiac pacemaker electrode
12.3
10.4
18
15
N17.8
ICD-10 Finland
Other acute renal failure
8.4
10.4
22
27
C08CA02
ATC
felodipine; oral
2.2
10.3
89
429
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
10.3
244
1659
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
10.3
90
436
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
10.3
91
443
I21.99
ICD-10 Finland
Myocardial infarction (acute) UNS unspecified coronary artery status
3.5
10.3
36
108
I41.8*D86.8
ICD-10 Finland
Sarcoid myocarditis
23.8
10.3
14
6
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.0
10.2
46
161
WX722
NOMESCO Finland
PEEP
2.8
10.2
52
195
R4190
NOMESCO Finland
Nutritional therapy
3.6
10.1
34
99
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.2
10.1
41
135
AQ1
HP
Conventional electrophysiological examination
10.3
10.1
19
19
I20.09
ICD-10 Finland
Unstable angina
2.6
10.0
61
251
L04AX01
ATC
azathioprine; systemic
3.4
10.0
37
115
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
4.1
9.9
27
68
D86.0
ICD-10 Finland
Sarcoidosis of lung
5.4
9.7
19
36
5AB14, ,
NOMESCO Finland
55.9
9.7
11
*
J01CA04
ATC
amoxicillin; systemic
1.8
9.7
499
4182
C08DB01
ATC
diltiazem; oral
2.7
9.6
54
213
A10AE04
ATC
insulin glargine; parenteral
2.2
9.6
85
413
UJF92
NOMESCO Finland
Capsular endoscopy
4.7
9.6
22
48
B03XA02
ATC
darbepoetin alfa; parenteral
4.1
9.6
26
65
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
101.5
9.4
10
*
4254A
ICD-9 Finland
Cardiomyopathy, Other primary cardiomyopathies
30.5
9.4
12
*
ZX197, ,
NOMESCO Finland
+∞
9.4
9
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
7.1
9.4
22
32
FPE96
NOMESCO Finland
Other implantation or replacement of transvenous cardiac pacemaker
8.9
9.3
19
22
B01AB04
ATC
dalteparin; parenteral
2.9
9.3
45
164
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
9.3
206
1367
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
9.3
189
1224
J01MA12
ATC
levofloxacin; systemic
1.9
9.2
148
891
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.1
9.2
39
132
A10BB12
ATC
glimepiride; oral
2.3
9.1
71
327
2BD01, ,
NOMESCO Finland
37.2
9.0
11
*
63
HP
Cardiac muscle biopsy
37.2
9.0
11
*
XFP02, ,
NOMESCO Finland
37.2
9.0
11
*
TFP52
NOMESCO Finland
Ablation treatment of ventricular tachycardia due to structural heart defect
37.2
9.0
11
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.1
9.0
97
509
N05BA01
ATC
diazepam; systemic, rectal
2.1
9.0
97
510
N05CF01
ATC
zopiclone; oral
1.7
9.0
230
1586
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.1
8.9
38
129
I20.9
ICD-10 Finland
Angina pectoris, unspecified
4.8
8.9
20
43
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
8.8
35
114
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.7
8.8
48
187
EBA10
NOMESCO Finland
Operative extraction of tooth
2.4
8.8
65
293
WX882
NOMESCO Finland
High dependency care
3.5
8.7
30
89
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.0
8.7
38
131
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
8.6
113
636
C01BB02
ATC
mexiletine; systemic
16.6
8.6
13
8
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
9.2
8.6
17
19
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.5
8.5
19
26
WW200
NOMESCO Finland
Immunization
3.8
8.4
25
67
M01AH05
ATC
etoricoxib; oral
0.6
8.3
208
2860
FJA00
NOMESCO Finland
Biopsy of right ventricle
+∞
8.3
8
*
FN2EG
NOMESCO Finland
Catheter-based alcohol septal ablation
+∞
8.3
8
*
FQA00
NOMESCO Finland
Orthotopic transplantation of heart
+∞
8.3
8
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.0
8.3
96
518
R60.0
ICD-10 Finland
Localized oedema
2.0
8.2
91
483
M01AE01
ATC
ibuprofen; systemic, rectal
0.6
8.1
411
4797
A10BA02
ATC
metformin; oral
1.7
8.1
218
1514
ZXA05
NOMESCO Finland
Left side
1.7
8.0
183
1217
A28
ICPC
Limited function/disability NOS
1.8
8.0
144
895
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
8.0
127
760
J01FF01
ATC
clindamycin; systemic
1.7
7.9
180
1194
R50.9
ICD-10 Finland
Fever, unspecified
1.9
7.9
106
600
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.1
7.8
76
383
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
2.4
7.8
52
223
A02BC02
ATC
pantoprazole; systemic
1.6
7.8
438
3627
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.3
7.8
62
289
FPG04
NOMESCO Finland
Insertion of internal defibrillator, atrial and chamber electrode
45.5
7.7
9
*
FXD00
NOMESCO Finland
Use of ECHLA without concurrent surgical procedure
45.5
7.7
9
*
J01DB01
ATC
cefalexin; oral
1.8
7.7
510
4403
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
4.6
7.7
18
40
E66.00
ICD-10 Finland
Metabolic syndrome
2.6
7.7
45
182
C01BA01
ATC
quinidine; oral
8.2
7.6
16
20
74
HP
Initial installation of the atrial pacemaker
18.6
7.6
11
6
FPH96
NOMESCO Finland
Other removal of cardiac pacemaker or cardioverter-defibrillator
12.0
7.6
13
11
R4120
NOMESCO Finland
Occupational therapy
2.4
7.6
50
214
I44.1
ICD-10 Finland
Atrioventricular block, second degree
3.4
7.5
26
78
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.9
7.4
35
126
FPG42
NOMESCO Finland
Replacement of electrode(s) in transvenous cardioverter-defibrillator
81.0
7.4
8
*
I42.4
ICD-10 Finland
Endocardial fibroelastosis
81.0
7.4
8
*
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
81.0
7.4
8
*
FM1LE
NOMESCO Finland
Combined ultrasound and EKG examination of heart with tolerance test
11.0
7.3
13
12
N02AX02
ATC
tramadol; systemic, rectal
1.6
7.3
288
2182
T86.2
ICD-10 Finland
Heart transplant failure and rejection
+∞
7.3
7
*
3A149, ,
NOMESCO Finland
+∞
7.3
7
*
FPH20
NOMESCO Finland
Removal of epicardial pacemaker or cardioverter-defibrillator
+∞
7.3
7
*
120, ,
NOMESCO Finland
+∞
7.3
7
*
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.2
7.3
65
317
A12AA04
ATC
calcium carbonate; oral
4.4
7.3
18
42
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.3
7.2
56
258
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.9
7.2
34
123
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.4
7.2
48
207
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
30.4
7.2
9
*
FPH00
NOMESCO Finland
Transvenous extraction of transvenous cardiac pacemaker or cardioverter-defibrillator
30.4
7.2
9
*
AS6
HP
Biventricular physiological heart failure pacemaker insertion DDD (R)
30.4
7.2
9
*
42509
ICD-8 Finland
Cardiomyopathy, Unspecified
30.4
7.2
9
*
S97
ICPC
Chronic ulcer skin
2.3
7.1
56
259
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
7.1
61
293
J01MA14
ATC
moxifloxacin; systemic
2.1
7.1
69
348
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
12.2
7.1
12
10
TFN04, ,
NOMESCO Finland
12.2
7.1
12
10
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.2
7.1
27
86
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.3
7.0
18
43
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
2.9
7.0
32
113
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
7.0
46
197
GD1AD
NOMESCO Finland
Thorax CT examination
2.3
7.0
51
229
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.3
6.9
26
82
Z95.9
ICD-10 Finland
Presence of cardiac and vascular implant and graft, unspecified
14.0
6.9
11
8
R04.2
ICD-10 Finland
Haemoptysis
2.7
6.8
36
138
E66.01
ICD-10 Finland
Obesity due to excess calories
2.4
6.8
46
199
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
11.1
6.8
12
11
C10AA03
ATC
pravastatin; oral
2.1
6.8
65
326
E85.4
ICD-10 Finland
Organ-limited amyloidosis
40.5
6.8
8
*
J96.1
ICD-10 Finland
Chronic respiratory failure
3.3
6.8
25
78
61
HP
Catheterization and pressure measurement of the left side of the heart
3.4
6.8
24
73
FPE36
NOMESCO Finland
Implantation of biventricular cardioverter-defibrillator with ventricular electrodes
22.8
6.7
9
*
I24.0
ICD-10 Finland
Coronary thrombosis not resulting in myocardial infarction
22.8
6.7
9
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.7
6.7
35
134
A10AC01
ATC
insulin (human); parenteral
2.1
6.6
61
301
Z51.5
ICD-10 Finland
Palliative care
2.0
6.6
70
364
RS221, ,
NOMESCO Finland
5.6
6.6
18
33
R2110
NOMESCO Finland
Giving the first information
2.6
6.6
38
153
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.0
6.5
68
352
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.1
6.5
26
85
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.5
6.5
22
65
AT7
HP
Replacing the pacemaker VVI (R) S
70.5
6.4
7
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
6.4
240
1783
FM1CD
NOMESCO Finland
Very extensive CT of heart
14.5
6.4
10
7
AQ2
HP
Electrophysiological electroanatomical examination
14.5
6.4
10
7
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.6
6.4
169
1159
L04AA01
ATC
[U] ciclosporin
6.6
6.4
15
23
G47.3
ICD-10 Finland
Sleep apnoea
1.6
6.4
153
1024
FPJ00
NOMESCO Finland
Revision of pacemaker pulse generator or electrode
11.2
6.3
11
10
K99
ICPC
Cardiovascular disease other
3.1
6.3
26
87
AT8
HP
Physiological pacemaker replacement DDD (R) S
+∞
6.3
6
*
3A422, ,
NOMESCO Finland
+∞
6.3
6
*
I43.1
ICD-10 Finland
Cardiomyopathy in metabolic diseases
+∞
6.3
6
*
474, ,
NOMESCO Finland
+∞
6.3
6
*
FXE00
NOMESCO Finland
Use of ECLA
+∞
6.3
6
*
E66.9
ICD-10 Finland
Obesity, unspecified
3.1
6.3
25
82
4259X
ICD-9 Finland
Cardiomyopathy, Secondary cardiomyopathy, unspecified
27.0
6.2
8
*
A10AE05
ATC
insulin detemir; parenteral
2.3
6.2
45
201
C01BC04
ATC
flecainide; systemic
2.7
6.2
33
127
WX730
NOMESCO Finland
Conventional respirator
5.1
6.2
18
36
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
6.2
50
234
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.6
6.2
35
139
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.2
6.2
54
261
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.5
6.2
39
164
C08CA05
ATC
nifedipine; systemic
2.2
6.2
50
235
I95.1
ICD-10 Finland
Orthostatic hypotension
2.5
6.1
38
158
K90
ICPC
Stroke/cerebrovascular accident
2.8
6.1
29
105
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
6.8
6.1
14
21
WX402
NOMESCO Finland
General anaesthesia
1.7
6.0
118
747

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
489
1913
7.40
122.06
12.2
3.1
3898.54
1547.49
ng/l
11.93
472
1643
301
801
6.16
114.69
4.6
2.4
21.23
22.69
%
1.04
283
686
307
842
6.04
112.81
4.5
2.4
2.32
2.28
g/l
0.68
289
777
320
921
5.90
111.03
4.5
2.5
12.41
12.61
umol/l
0.18
305
857
230
517
6.36
104.07
7.8
3.2
534.52
226.87
ng/l
6.94
225
471
224
536
5.87
93.71
25.7
6.8
13.17
10.27
mmol/l
4.83
215
508
266
927
4.18
66.62
11.7
3.3
0.83
0.81
mmol/l
1.09
252
864
122
233
6.22
63.35
4.3
3.1
3.97
4.38
pmol/l
3.00
113
200
237
791
4.15
62.47
11.0
5.4
1.13
1.02
mmol/l
5.28
219
732
190
542
4.55
61.82
5.2
2.7
26.41
7.48
ug/l
4.05
177
481
180
494
4.66
61.52
17.7
8.9
—
—
—
0
0
170
508
4.18
51.12
3.0
3.0
64.15
66.14
g/l
2.45
160
458
485
2850
3.82
50.08
50.1
17.7
1.63
1.33
inr
6.46
124
799
173
540
4.01
48.77
16.3
7.3
1.57
1.40
mmol/l
0.93
164
526
312
1437
3.27
47.61
3.7
2.2
3.42
3.18
mg/l
0.71
277
1219
93
179
5.90
47.40
5.4
2.4
22.36
21.79
s
0.23
86
164
236
939
3.38
45.62
7.0
2.1
33.24
29.86
s
9.34
231
913
388
2069
3.19
45.29
5.2
2.7
175.39
162.72
ug/l
0.43
367
1870
263
1125
3.26
44.97
9.9
3.9
677.33
277.59
ng/l
0.81
258
941
87
165
5.94
44.97
2.8
3.1
0.82
0.89
nmol/l
0.40
65
129
173
580
3.71
43.50
7.2
3.6
2.05
2.00
mmol/l
0.06
154
478
173
585
3.67
42.88
7.2
3.6
5.93
5.85
kpa
0.40
168
565
98
216
5.17
42.87
4.8
2.2
2269.58
711.55
ug/l
0.47
93
204
338
1726
3.01
41.53
7.4
4.3
—
—
—
0
0
60
93
7.01
37.69
1.8
1.5
25.48
32.10
g/l
2.76
51
82
57
86
7.17
36.69
1.6
1.4
—
—
—
0
0
52
71
7.88
36.54
1.5
1.2
4.40
6.89
u/ml
0.35
25
35
322
1691
2.80
36.14
8.2
4.1
7.40
7.40
ph
0.12
56
330
37
33
11.83
35.63
1.1
1.1
—
—
—
0
0
448
2829
2.90
34.49
16.1
6.9
1.19
1.21
mmol/l
8.19
396
2403
422
2600
2.80
33.78
16.4
6.2
1.19
1.21
mmol/l
8.20
404
2355
102
279
4.15
33.77
2.0
1.9
1.52
1.56
g/l
0.13
86
252
179
714
3.08
33.06
15.4
7.6
10.98
11.78
kpa
1.68
171
687
179
714
3.08
33.06
15.4
7.6
4.95
5.11
kpa
0.91
169
685
178
712
3.07
32.67
15.2
7.7
0.29
1.24
mmol/l
2.27
141
571
383
2285
2.66
32.06
9.7
4.0
76.81
59.18
ng/l
0.40
344
1778
262
1316
2.67
31.00
12.5
6.7
—
—
—
0
0
83
208
4.43
30.74
4.4
3.9
47.83
49.84
mg/l
0.05
72
169
83
208
4.43
30.74
4.4
3.9
59.05
89.50
mg/l
0.46
73
167
38
10
40.27
30.58
4.5
6.9
—
—
—
0
0
415
2615
2.64
30.39
12.1
5.7
0.66
0.61
e9/l
3.81
368
2252
36
39
9.72
30.29
2.4
2.3
—
—
—
0
0
415
2625
2.62
29.99
12.1
5.7
0.04
0.04
e9/l
0.12
367
2270
35
37
9.94
29.97
1.2
1.2
—
—
—
0
0
48
76
6.74
29.46
1.6
1.4
113.33
102.00
u/ml
—
6
11
266
1374
2.59
29.38
8.3
4.1
65.28
86.13
%
24.42
257
1341
421
2701
2.60
29.20
12.9
5.9
0.18
0.20
e9/l
1.28
378
2371
417
2667
2.59
29.05
12.2
5.7
1.59
1.89
e9/l
4.31
373
2356
46
72
6.80
28.53
1.8
1.3
11567.12
129868.10
e6/l
0.78
33
42
135
498
3.16
28.13
6.7
2.9
4.34
4.43
kpa
0.16
130
479
79
204
4.27
28.08
4.5
3.8
1.06
2.17
ratio
—
5
18
439
2913
2.58
27.70
13.9
6.4
15.28
12.07
umol/l
7.47
428
2760
169
714
2.85
27.59
2.8
2.5
1.81
1.78
%
0.17
152
641
75
189
4.36
27.50
3.1
2.8
34.87
37.40
g/l
2.25
67
163
45
73
6.55
26.97
1.8
1.4
—
—
—
0
0
120
425
3.24
26.69
2.9
2.7
—
—
—
0
0
80
217
4.07
26.58
3.0
2.7
10.22
10.69
g/l
0.35
72
190
47
81
6.18
26.54
1.9
1.3
692.11
1937.84
e6/l
2.24
38
56
122
442
3.17
26.09
2.1
1.6
—
—
—
0
0
303
1737
2.40
25.88
4.5
2.2
351.85
256.10
u/l
0.37
287
1632
381
2417
2.40
25.77
12.9
5.8
0.59
0.65
%
1.26
365
2255
223
1123
2.51
25.27
8.8
1.7
1.63
1.31
mg/l
0.63
179
878
64
153
4.53
25.05
4.0
4.1
—
—
—
0
0
387
2492
2.38
25.01
13.2
6.1
9.22
8.92
%
1.08
370
2324
385
2479
2.37
24.80
13.0
5.8
2.53
2.89
%
2.80
369
2308
152
639
2.80
24.80
2.8
2.8
10.49
9.52
umol/l
0.31
136
561
382
2457
2.36
24.59
13.0
6.3
—
—
—
0
0
443
3041
2.45
24.52
15.1
9.0
4.93
4.22
e9/l
6.66
394
2670
388
2528
2.34
24.01
13.1
6.0
21.53
26.42
%
15.41
371
2358
117
435
3.06
23.81
6.1
3.8
125.57
88.34
ng/l
3.31
111
379
274
1547
2.34
23.72
4.5
3.3
—
—
—
0
0
46
87
5.62
23.58
1.6
1.1
362.00
253.92
u/ml
1.14
40
48
139
574
2.81
23.35
2.0
1.6
—
—
—
0
0
382
2494
2.30
23.22
12.7
5.7
63.42
58.08
%
14.65
366
2337
60
146
4.43
22.94
3.3
2.0
10.80
12.77
mg/l
0.81
54
130
181
866
2.51
22.52
3.3
2.0
—
—
—
0
0
43
80
5.69
22.42
1.7
1.6
—
—
—
0
0
459
3282
2.38
21.89
14.3
5.1
7.18
6.85
mmol/l
1.73
443
3102
86
279
3.40
21.86
1.6
1.4
—
—
—
0
0
261
1485
2.27
21.76
4.0
2.7
2227.01
6775.24
umol/l
1.34
228
1269
277
1628
2.23
21.20
4.6
3.3
0.74
0.55
e6/l
0.43
227
1260
131
552
2.72
21.00
2.5
2.3
0.19
0.21
g/l
1.78
121
515
373
2477
2.20
20.88
7.1
4.8
33.40
34.97
g/l
5.82
352
2292
116
463
2.83
20.60
2.2
1.5
—
—
—
0
0
281
1676
2.20
20.58
3.6
3.3
60.03
33.59
u/l
1.32
266
1584
37
65
5.98
20.45
1.8
1.3
—
—
—
0
0
51
121
4.49
20.10
1.5
1.2
—
—
—
0
0
290
1774
2.15
19.69
4.8
3.5
87.90
125.91
e6/l
0.36
242
1390
351
2310
2.14
19.68
21.5
10.1
0.00
0.00
e9/l
0.19
293
1905
27
11
25.53
19.68
1.1
1.2
—
—
—
0
0
27
11
25.53
19.68
1.1
1.0
—
—
—
0
0
57
154
3.96
18.93
3.2
3.2
33.33
33.73
umol/l
0.04
52
135
232
1317
2.19
18.90
4.0
2.4
—
—
—
0
0
87
310
3.09
18.87
22.6
10.6
—
—
—
0
0
310
2004
2.05
17.59
5.5
4.0
47.57
138.69
e6/l
1.57
250
1480
99
397
2.76
17.29
5.2
3.9
7.41
7.40
ph
0.29
21
47
278
1739
2.05
17.16
4.2
2.5
—
—
—
0
0
55
156
3.76
17.05
8.4
3.4
—
—
—
0
0
27
42
6.67
16.77
1.2
1.1
—
—
—
0
0
139
676
2.35
16.13
2.6
1.7
—
—
—
0
0
48
130
3.91
15.87
5.3
2.5
—
—
—
0
0
128
607
2.38
15.70
1.2
1.3
328.89
436.44
titre
0.51
18
135
31
60
5.38
15.47
2.2
2.5
—
—
—
0
0
181
999
2.13
15.33
3.8
2.9
1.00
1.03
e6/l
0.05
107
596
213
1253
2.04
15.19
3.6
2.7
4.84
4.48
e6/l
0.23
198
1127
27
47
5.95
15.04
1.5
1.5
15.00
13.60
u/l
0.40
27
42
172
937
2.14
15.04
3.9
3.2
2.77
1.69
e6/l
0.83
97
539
460
3534
2.05
14.97
6.5
4.8
27.20
3605.37
e6/l
—
10
65
110
500
2.45
14.77
2.5
2.5
33.02
33.06
u/l
0.00
94
422
47
132
3.76
14.76
6.9
3.5
—
—
—
0
0
80
319
2.72
14.03
1.8
1.6
1.50
1.53
g/l
0.02
70
290
113
533
2.36
13.93
2.7
2.6
76.23
68.37
e9/l
0.89
81
429
267
1740
1.91
13.88
3.5
2.6
56.91
107.74
u/l
0.57
253
1609
203
1213
1.98
13.60
3.7
3.1
524.88
557.06
mosm/kgh2o
1.56
182
1037
44
125
3.70
13.60
4.7
2.5
15.29
16.05
%
0.50
27
65
45
132
3.59
13.27
1.6
1.8
—
—
—
0
0
508
4128
2.08
13.05
16.8
7.8
84.81
80.22
u/l
0.88
492
3858
49
164
3.15
11.75
5.3
3.3
2.07
1.59
mg/l
2.75
44
146
87
398
2.37
11.41
2.1
2.7
10.20
10.72
g/l
0.45
80
356
26
57
4.71
11.27
11.9
3.1
—
—
—
0
0
17
10
17.42
11.24
1.1
1.6
—
—
—
0
0
23
29
8.18
10.67
1.7
1.3
47.44
59.42
%
0.47
18
19
38
116
3.42
10.56
5.2
2.5
—
—
—
0
0
218
1427
1.80
10.53
2.1
1.6
19.07
20.40
nmol/l
0.63
193
1197
50
187
2.81
9.88
1.3
1.5
—
—
—
0
0
41
137
3.13
9.87
4.0
2.2
124.88
129.97
g/l
0.54
32
102
34
102
3.46
9.71
1.2
1.2
57.79
25.75
u/l
0.39
29
86
88
436
2.18
9.51
6.3
4.6
—
—
—
0
0
21
28
7.71
9.48
1.4
1.5
—
—
—
0
0
462
3798
1.76
9.39
10.1
4.2
—
—
—
0
0
21
45
4.79
9.35
14.1
3.1
—
—
—
0
0
457
3751
1.75
9.28
5.7
3.6
15.80
15.07
pmol/l
5.93
429
3319
145
868
1.86
9.21
1.7
1.4
2.73
2.70
g/l
0.06
95
501
39
132
3.08
9.20
9.8
4.1
3.33
2.40
mmol/l
1.07
29
91
249
1746
1.69
9.15
3.4
3.3
131.75
294.80
mg/l
1.04
200
1155
254
1792
1.69
9.11
3.4
3.2
6.95
7.61
mmol/l
1.89
221
1473
16
14
11.68
9.10
1.8
1.3
—
—
—
0
0
261
1879
1.65
8.53
4.6
3.4
2.33
2.35
mmol/l
1.13
217
1631
316
2390
1.63
8.46
2.4
2.1
92.21
93.32
pmol/l
0.17
171
1232
40
145
2.87
8.38
1.6
1.4
0.25
0.23
g/l
0.37
34
139
323
2485
1.60
7.86
4.4
2.7
—
—
—
0
0
254
1849
1.62
7.75
4.1
3.8
26.47
8.07
mg/mmol
3.14
197
1193
439
3644
1.64
7.72
5.9
4.6
—
—
—
0
0
57
258
2.33
7.63
11.5
4.7
—
—
—
0
0
26
77
3.48
7.60
1.1
1.1
—
—
—
0
0
458
3855
1.65
7.48
7.0
4.2
17.15
13.40
mm/h
4.04
435
3515
29
94
3.18
7.37
2.5
2.9
—
—
—
0
0
59
276
2.25
7.32
2.3
1.9
2.31
2.43
ug/l
0.03
53
242
61
293
2.19
7.11
5.2
4.0
—
—
—
0
0
14
16
8.92
7.07
1.1
1.1
191.79
247.66
iu/ml
0.26
14
16
53
242
2.30
6.97
6.9
4.2
1.47
1.39
mmol/l
0.23
53
237
15
21
7.29
6.73
1.5
1.9
—
—
—
0
0
18
45
4.09
6.66
2.4
1.7
10.25
11.15
%
0.43
18
45
234
1736
1.55
6.28
3.6
3.4
—
—
—
0
0
10
8
12.67
6.10
1.0
1.0
—
—
—
0
0
270
2085
1.51
5.92
3.2
2.2
76.17
78.23
nmol/l
0.54
242
1812
84
485
1.84
5.87
2.6
2.0
426.28
380.57
nmol/l
0.59
79
444
14
23
6.20
5.71
4.9
2.0
923.71
909.61
u/ml
0.02
14
23
7
294
0.23
5.56
1.1
1.4
—
—
—
0
0
31
128
2.49
5.12
1.3
1.2
—
—
—
0
0
79
467
1.79
5.11
5.3
4.1
0.44
0.90
%
2.07
34
179
75
442
1.79
4.90
5.4
4.2
0.00
0.14
%
3.92
31
154
166
1201
1.51
4.80
4.6
3.9
—
—
—
0
0
79
476
1.75
4.79
1.7
1.5
—
—
—
0
0
53
283
1.95
4.71
1.5
1.3
—
—
—
0
0
12
22
5.54
4.62
2.5
2.4
—
—
—
0
0
70
412
1.78
4.60
4.9
4.1
0.18
0.53
%
2.88
28
147
79
483
1.72
4.56
3.4
1.4
—
—
—
0
0
558
5129
1.65
4.54
45.8
16.5
25.40
26.67
mg/l
0.45
519
4168
162
1190
1.48
4.30
2.1
1.8
1283.44
1185.68
nmol/l
0.59
129
898
69
413
1.75
4.29
5.2
4.2
0.24
0.11
%
0.21
25
125
12
25
4.87
4.20
1.0
1.0
—
—
—
0
0
24
97
2.53
4.17
1.9
1.6
1.52
5.62
iu/l
—
7
26
10
17
5.96
4.14
1.1
1.1
—
—
—
0
0
25
106
2.41
3.95
4.2
3.8
60.32
59.11
%
0.16
25
106
12
27
4.51
3.95
1.0
1.0
—
—
—
0
0
75
471
1.67
3.93
5.0
3.3
—
—
—
0
0
17
60
2.88
3.82
4.4
2.6
2.71
1.89
g/24h
0.29
12
27
24
102
2.41
3.78
2.8
3.3
3.90
4.51
e9/l
0.65
24
102
7
8
8.83
3.78
5.7
6.1
4.36
6.81
mmol/l
—
7
8
131
953
1.47
3.61
1.2
1.2
1.17
1.39
u/ml
0.15
35
253
23
99
2.37
3.54
4.9
2.7
—
—
—
0
0
23
99
2.37
3.54
1.1
1.6
—
—
—
0
0
16
58
2.80
3.44
1.1
1.3
—
—
nmol/l
—
0
0
14
47
3.02
3.43
1.4
1.3
5.86
7.39
g/l
—
7
34
14
47
3.02
3.43
1.4
1.3
2.16
2.54
g/l
—
8
34
14
47
3.02
3.43
1.4
1.3
0.46
0.43
g/l
—
8
33
94
647
1.53
3.38
1.8
1.4
—
—
—
0
0
7
10
7.06
3.37
1.0
1.0
16.24
17.44
g/l
—
7
10
14
49
2.90
3.21
1.4
1.2
—
—
—
0
0
101
714
1.49
3.20
1.2
1.3
—
—
—
0
0
32
167
1.96
3.10
1.4
1.2
—
—
—
0
0
504
4635
1.40
3.09
6.8
4.5
2.16
2.00
mu/l
2.01
478
4148
13
41
3.21
3.07
1.2
1.2
—
—
—
0
0
16
62
2.62
3.06
1.1
1.3
—
—
—
0
0
300
2563
1.32
3.02
6.5
5.4
0.00
0.00
estimate
-0.00
63
474
37
205
1.85
3.01
2.2
2.0
—
—
—
0
0
474
4324
1.36
3.00
53.6
19.4
15.76
15.33
%
0.93
466
4255
19
82
2.36
2.94
1.3
1.7
0.67
0.85
g/l
0.28
11
61
14
52
2.73
2.90
1.5
1.2
—
—
—
0
0
212
1738
1.33
2.81
8.3
4.3
—
—
—
0
0
14
53
2.68
2.81
1.4
1.1
—
—
—
0
0
7
14
5.04
2.73
1.6
1.7
—
—
—
0
0
16
66
2.46
2.73
1.1
1.2
—
—
—
0
0
11
35
3.18
2.65
1.2
1.2
—
—
—
0
0
363
3219
1.29
2.63
4.0
3.3
86.62
56.30
u/l
4.25
338
2958
141
1100
1.36
2.58
2.9
3.2
2.48
2.46
mmol/l
0.99
111
960
244
2061
1.30
2.56
4.5
3.7
6.36
5.78
ph
—
7
121
18
81
2.26
2.56
1.6
1.9
32.89
33.25
pg
0.12
18
81
51
326
1.61
2.55
1.1
1.2
—
—
—
0
0
6
11
5.49
2.55
1.0
1.2
—
—
—
0
0
17
75
2.30
2.53
2.9
3.8
—
—
—
0
0
21
102
2.09
2.50
1.0
1.4
—
—
—
0
0
38
226
1.72
2.49
1.8
3.0
0.64
0.23
g/l
1.01
23
91
296
2570
1.28
2.48
5.0
4.0
0.00
0.01
estimate
0.74
67
513
5
160
0.31
2.44
1.2
1.2
—
—
—
0
0
20
97
2.10
2.39
1.2
1.5
—
—
—
0
0
5
8
6.29
2.37
4.4
1.9
—
—
—
0
0
7
187
0.37
2.31
1.1
1.4
—
—
—
0
0
297
2597
1.27
2.30
5.0
4.0
0.00
0.00
estimate
-0.00
59
457
10
34
2.97
2.29
1.1
1.1
—
—
—
0
0
7
18
3.92
2.25
1.0
1.2
—
—
—
0
0
5
9
5.59
2.21
3.0
2.3
—
—
—
0
0
5
9
5.59
2.21
1.0
1.2
—
—
—
0
0
12
49
2.48
2.11
1.3
1.3
—
—
—
0
0
7
20
3.53
2.06
3.6
1.6
—
—
—
0
0
13
56
2.35
2.06
1.0
1.3
—
—
—
0
0
7
21
3.36
1.97
1.0
1.5
—
—
—
0
0
18
91
2.01
1.97
1.7
2.2
—
—
—
0
0
17
85
2.03
1.91
1.2
1.1
—
—
—
0
0
16
79
2.05
1.86
1.1
1.1
—
—
—
0
0
11
46
2.42
1.86
1.1
1.0
—
—
—
0
0
5
12
4.19
1.82
2.8
7.4
—
—
—
0
0
134
1620
0.78
1.77
3.1
3.2
—
—
—
0
0
6
18
3.35
1.75
8.3
3.7
53.42
50.78
%
—
6
18
5
13
3.87
1.72
1.8
1.4
—
—
—
0
0
12
55
2.20
1.68
1.4
1.1
1.86
1.68
nmol/l
0.20
12
48
5
131
0.38
1.64
1.2
1.6
—
—
—
0
0
20
113
1.79
1.62
2.6
2.8
—
—
—
0
0
12
56
2.16
1.62
1.0
1.2
—
—
—
0
0
5
14
3.59
1.62
1.0
1.1
—
—
—
0
0
5
14
3.59
1.62
1.0
1.3
—
—
—
0
0
42
291
1.47
1.55
2.5
2.5
—
—
—
0
0
166
1413
1.24
1.53
5.8
4.3
0.00
0.00
estimate
-0.00
60
451
19
108
1.78
1.52
1.6
1.5
—
—
—
0
0
15
268
0.55
1.51
1.4
1.3
—
—
—
0
0
5
127
0.39
1.51
1.2
1.6
—
—
—
0
0
14
72
1.97
1.49
2.3
1.4
—
—
—
0
0
9
37
2.45
1.48
2.0
1.7
38.41
35.98
%
—
9
37
16
88
1.84
1.42
1.3
1.4
—
—
—
0
0
15
81
1.87
1.41
1.2
1.1
—
—
—
0
0
560
5399
1.28
1.34
62.3
19.6
138.95
139.61
mmol/l
5.84
551
5249
25
160
1.59
1.33
1.9
1.5
—
—
—
0
0
11
54
2.06
1.33
1.4
1.3
—
—
—
0
0
0
40
0.00
1.33
0.0
1.2
—
0.14
—
0
5
6
24
2.51
1.30
1.0
1.0
—
—
—
0
0
8
34
2.37
1.29
2.8
2.5
—
—
—
0
0
560
5414
1.26
1.19
62.8
19.7
4.07
4.01
mmol/l
7.03
549
5258
8
38
2.12
1.18
1.1
1.0
—
—
—
0
0
21
133
1.60
1.18
2.2
2.4
—
—
—
0
0
6
127
0.47
1.17
1.0
1.1
—
—
—
0
0
33
233
1.44
1.15
1.2
1.2
32.12
137.10
iu/ml
—
9
81
57
443
1.31
1.13
5.5
4.1
—
—
—
0
0
509
4884
1.20
1.10
7.9
6.4
43.94
40.77
mmol/mol
8.11
482
4478
5
21
2.39
1.09
2.8
1.4
0.13
0.31
nmol/l
—
5
12
149
1309
1.18
0.99
1.5
1.3
—
—
—
0
0
7
36
1.95
0.97
1.4
1.2
—
—
—
0
0
10
54
1.87
0.97
1.0
1.2
—
—
—
0
0
22
149
1.49
0.96
2.0
1.7
7660.67
19219.20
e6/l
1.37
15
110
545
5285
1.20
0.92
38.7
15.7
—
—
—
0
0
221
2012
1.15
0.92
2.2
2.2
—
—
—
0
0
92
781
1.21
0.90
1.2
1.2
37.50
37.46
iu/ml
0.00
42
248
501
4830
1.17
0.88
5.8
4.2
1.35
1.30
mmol/l
0.84
471
4353
80
674
1.21
0.85
1.2
1.3
—
—
—
0
0
39
303
1.31
0.81
3.3
4.1
—
—
—
0
0
67
558
1.22
0.80
9.7
4.4
—
—
—
0
0
70
588
1.21
0.77
1.5
1.3
—
—
—
0
0
7
39
1.80
0.72
1.1
3.3
—
—
—
0
0
433
4158
1.13
0.72
61.0
21.6
327.59
332.49
g/l
20.45
423
4126
132
1459
0.88
0.64
2.7
3.1
0.65
0.79
ug/l
1.27
86
987
31
243
1.29
0.64
1.4
3.5
15036.04
5817.30
u/ml
0.25
24
204
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
24
183
1.32
0.60
1.7
2.4
82.78
67.92
ug/min
—
10
108
24
184
1.32
0.58
4.5
6.3
1.32
1.33
mmol/l
0.04
19
159
555
5436
1.15
0.58
22.5
11.2
31.46
26.22
u/l
1.10
540
5226
6
36
1.67
0.57
4.8
16.2
—
—
—
0
0
27
340
0.79
0.56
3.7
3.2
4.49
6.89
e9/l
0.67
20
267
242
2562
0.91
0.53
4.0
5.2
2.01
3.02
ug/l
1.57
208
2280
46
388
1.20
0.53
1.6
1.5
—
—
—
0
0
6
41
1.47
0.50
1.2
1.8
—
—
—
0
0
10
143
0.69
0.48
1.2
1.1
—
—
—
0
0
510
4987
1.11
0.47
6.1
4.7
1.23
1.42
mmol/l
21.99
479
4524
7
47
1.49
0.47
1.4
1.4
—
—
—
0
0
42
492
0.84
0.46
1.5
1.5
—
—
—
0
0
8
120
0.66
0.46
1.9
3.6
17.93
436.41
u/ml
—
8
114
513
5026
1.10
0.43
6.1
4.8
3.96
4.48
mmol/l
25.39
491
4600
5
31
1.62
0.43
1.2
1.4
—
—
—
0
0
130
1399
0.91
0.41
1.5
1.7
1.54
1.34
mmol/l
1.85
115
1143
37
317
1.18
0.38
3.7
3.1
0.29
0.28
e6/l
0.04
37
310
9
68
1.33
0.37
3.1
2.8
—
—
—
0
0
13
168
0.77
0.36
1.0
1.1
—
—
—
0
0
9
126
0.71
0.35
1.8
2.0
228.89
220.28
pmol/l
—
9
116
6
43
1.40
0.35
1.0
3.0
—
—
—
0
0
80
731
1.11
0.34
1.1
1.3
11.96
10.69
u/ml
0.07
31
269
16
127
1.27
0.33
8.2
3.8
19.29
29.00
mg/l
0.76
11
81
12
92
1.31
0.32
1.2
1.7
588.33
280.77
mu/l
0.64
12
86
7
52
1.35
0.31
1.0
1.1
—
—
—
0
0
131
1389
0.93
0.30
5.1
3.7
—
—
—
0
0
12
94
1.28
0.28
1.3
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
2.0
—
14.82
—
0
13
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
7
59
1.19
0.18
1.0
3.8
—
—
—
0
0
5
68
0.73
0.17
1.4
2.2
—
—
—
0
0
5
70
0.71
0.16
1.0
3.3
12.00
28.19
u/ml
—
5
70
8
70
1.14
0.16
1.8
2.5
—
—
—
0
0
60
637
0.94
0.16
2.1
4.2
19.58
30.33
ug/l
0.25
54
538
31
283
1.10
0.16
1.2
1.2
—
—
—
0
0
9
81
1.11
0.15
1.7
2.5
—
—
—
0
0
9
82
1.10
0.15
1.7
2.0
—
—
—
0
0
40
372
1.08
0.14
3.4
3.2
—
—
—
0
0
7
88
0.79
0.14
1.0
1.3
—
—
—
0
0
520
5157
1.04
0.14
6.4
5.3
2.28
2.62
mmol/l
15.11
491
4682
122
1260
0.96
0.13
1.9
1.8
443.67
3853997.34
pmol/l
0.50
99
1038
20
183
1.10
0.10
12.8
13.1
—
—
—
0
0
50
524
0.95
0.10
2.1
2.4
118.44
152.90
ug/g
0.74
39
416
5
47
1.06
0.09
2.0
3.3
—
—
—
0
0
17
184
0.92
0.07
4.2
4.9
—
—
—
0
0
9
84
1.07
0.07
1.7
2.5
—
—
—
0
0
9
84
1.07
0.07
1.7
2.5
—
—
—
0
0
51
492
1.04
0.07
3.1
2.3
10.44
12.99
nmol/l
1.32
46
436
560
5620
0.97
0.06
64.8
24.2
129.99
135.26
g/l
9.55
551
5511
560
5618
0.98
0.05
64.2
24.1
4.36
4.47
e12/l
3.73
545
5435
560
5617
0.98
0.05
67.5
24.2
39.49
40.03
%
1.35
536
5195
560
5617
0.98
0.05
64.1
24.0
92.43
91.54
fl
3.77
551
5515
560
5617
0.98
0.05
64.0
24.0
30.35
30.47
pg
0.72
551
5514
560
5615
0.98
0.04
64.3
24.1
223.97
239.18
e9/l
6.30
547
5456
561
5619
0.99
0.01
64.3
24.1
7.38
6.85
e9/l
5.89
546
5439
505
5041
1.01
0.01
5.8
5.0
6.41
6.09
mmol/l
4.04
471
4527
29
296
0.98
0.00
2.8
2.8
—
—
—
0
0
26
255
1.02
0.00
1.3
1.2
—
—
—
0
0
17
174
0.98
0.00
1.2
3.3
49.12
55.63
u/ml
0.10
17
167
16
163
0.98
0.00
1.3
1.4
248.55
267.60
ug/g
0.14
11
89
117
1165
1.01
0.00
5.9
4.4
1.02
1.02
kg/l
0.37
15
179
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
0.00
1.8
2.5
—
—
—
0
0
9
96
0.94
-0.00
6.7
2.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
17
170
1.00
-0.00
1.9
1.9
37.76
41.43
nmol/l
0.24
17
161
0
8
0.00
-0.00
0.0
1.4
—
37.00
—
0
8
5
53
0.94
-0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint I9_HEARTFAIL_AND_HYPERTCARDIOM and mortality.

Females

Parameter HR [95% CI] p-value
I9_HEARTFAIL_AND_HYPERTCARDIOM 2.312 [1.99, 2.68] < 0.001
Birth year 0.995 [0.99, 1.0] 0.234

During the follow-up period (1.1.1998 — 31.12.2019), 625 out of 1166 females with I9_HEARTFAIL_AND_HYPERTCARDIOM died.

Males

Parameter HR [95% CI] p-value
I9_HEARTFAIL_AND_HYPERTCARDIOM 2.417 [2.08, 2.81] < 0.001
Birth year 0.988 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 885 out of 1729 males with I9_HEARTFAIL_AND_HYPERTCARDIOM died.

Mortality risk

Mortality risk for people of age

years, who have I9_HEARTFAIL_AND_HYPERTCARDIOM.

N-year risk Females Males
1 0.211% 0.397%
5 1.164% 2.836%
10 3.2% 7.472%
15 6.537% 13.271%
20 10.87% 22.039%

Relationships between endpoints

Index endpoint: I9_HEARTFAIL_AND_HYPERTCARDIOM – Heart failure and hypertrophic cardiomyopathy

GWS hits: 9

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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