No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
312 |
4. Check minimum number of eventsNone |
312 |
5. Include endpointsNone |
312 |
6. Filter based on genotype QC (FinnGen only) |
312 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10
- Name in latin
- Neoplasma benignum nasopharyngis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Nasopharynx
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Nasopharynx
- Benign neoplasm of mouth and pharynx
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1716 | 784 | 921 |
| Only index persons | 1545 | 733 | 812 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.03 |
| Only index persons | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 52.07 | 54.78 | 49.75 |
| Only index persons | 51.34 | 54.20 | 48.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 312 | 155 | 157 |
| Unadjusted period prevalence (%) | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | 56.74 | 54.98 | 58.49 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 270
- Matched controls
- 2698
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D10.6
ICD-10 Finland
Benign neoplasm: Nasopharynx
+∞
320.7
240
*
EMA30
NOMESCO Finland
Biopsy of rhinopharynx
376.3
61.0
59
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
15.5
51.1
89
83
EMB30
NOMESCO Finland
Adenotomy
31.1
25.1
33
12
UDQ12
NOMESCO Finland
Flexible laryngoscopy
8.5
18.0
40
54
21070
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Nasopharynx
+∞
16.8
16
*
J35.2
ICD-10 Finland
Hypertrophy of adenoids
25.0
16.7
23
10
DHA10
NOMESCO Finland
Biopsy of cavity of nose
35.8
16.0
20
6
2107A
ICD-9 Finland
Benign neoplasm of lip, oral cavity and pharynx, Nasopharynx
+∞
15.8
15
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
12.4
13.6
24
21
ENA10
NOMESCO Finland
Biopsy of pharynx
147.0
13.6
14
*
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
27.4
13.5
18
7
H65.2
ICD-10 Finland
Chronic serous otitis media
21.3
12.6
18
9
R01AD09
ATC
mometasone; nasal
2.5
11.3
133
760
H65.3
ICD-10 Finland
Chronic mucoid otitis media
11.3
11.0
20
19
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
13.9
10.3
17
13
UDC00
NOMESCO Finland
Ear microscopy
4.4
10.2
37
93
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.2
9.2
145
928
1290
FHL
Epipharyngoscopy
92.8
8.5
9
*
ENB00
NOMESCO Finland
Excision or exploration of lesion of pharynx
+∞
8.4
8
*
J34.2
ICD-10 Finland
Deviated nasal septum
5.2
7.8
23
47
H65.0
ICD-10 Finland
Acute serous otitis media
15.6
7.8
12
8
TDA90
NOMESCO Finland
Removal wax from ear
15.6
7.8
12
8
R01AD08
ATC
fluticasone; nasal
2.3
7.7
84
443
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
7.3
91
509
DHB10
NOMESCO Finland
Excision of lesion of internal nose
30.9
7.2
9
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.0
7.1
40
146
H66.0
ICD-10 Finland
Acute suppurative otitis media
4.0
7.0
27
73
H66.9
ICD-10 Finland
Otitis media, unspecified
4.6
6.9
23
54
R01BA52
ATC
pseudoephedrine, combinations; oral
2.1
6.8
88
499
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
41.1
6.8
8
*
J39.2
ICD-10 Finland
Other diseases of pharynx
12.7
6.6
11
9
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
6.3
67
347
C11.9
ICD-10 Finland
Malignant neoplasm: Nasopharynx, unspecified
+∞
6.3
6
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
5.1
6.2
18
37
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.5
6.1
50
225
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
12
21
5.90
6.64
1.4
1.1
—
—
—
0
0
195
1468
1.88
6.58
11.0
9.8
4.1
4.1
e9/l
0.09
165
1291
21
70
3.14
5.21
1.1
1.2
—
—
—
0
0
71
417
1.91
5.05
2.1
1.9
—
—
—
0
0
23
83
2.91
5.00
4.6
3.1
—
—
—
0
0
146
1065
1.70
4.97
4.7
4.6
35.1
35.5
g/l
0.42
134
1002
155
1150
1.69
4.94
5.8
5.8
1.2
1.2
mmol/l
0.06
143
1052
68
403
1.88
4.69
3.8
3.5
0.8
0.8
mmol/l
0.16
63
376
140
1022
1.67
4.67
2.1
2.0
97.3
95.4
pmol/l
0.16
75
524
165
1260
1.66
4.60
7.2
6.5
1.2
1.2
mmol/l
0.10
138
1066
227
1885
1.75
4.59
4.6
3.8
14.8
14.7
pmol/l
0.23
209
1698
23
88
2.74
4.51
2.3
1.7
—
—
—
0
0
189
1504
1.65
4.40
5.3
4.8
6.8
6.7
mmol/l
0.26
177
1408
23
94
2.56
3.98
2.6
1.9
—
—
—
0
0
42
230
1.95
3.64
1.8
2.0
312.3
364.1
nmol/l
0.79
36
207
91
633
1.62
3.48
2.5
2.3
—
—
—
0
0
16
58
2.85
3.47
1.3
1.3
—
—
—
0
0
221
1894
1.57
3.25
5.9
4.1
13.9
12.0
mm/h
0.99
206
1743
11
33
3.42
3.22
1.1
1.4
0.4
0.5
nmol/l
0.30
11
27
72
492
1.60
2.92
5.8
3.8
851.6
249.6
ng/l
0.71
56
386
28
144
2.04
2.91
1.8
1.6
—
—
—
0
0
93
677
1.53
2.87
3.3
2.8
323.7
6491.6
umol/l
2.67
85
582
148
1186
1.47
2.85
4.1
4.1
—
—
—
0
0
250
2236
1.59
2.75
22.6
15.6
39.9
40.1
%
0.13
172
1594
15
60
2.58
2.74
1.2
1.1
—
—
—
0
0
11
37
3.05
2.72
1.1
1.1
—
—
—
0
0
47
294
1.70
2.68
2.0
1.9
—
—
—
0
0
70
485
1.57
2.67
1.7
1.7
1076.0
1225.3
nmol/l
0.63
51
366
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
17
74
2.37
2.63
2.2
2.4
0.3
0.4
u/ml
0.40
11
36
224
1968
1.49
2.56
10.0
7.6
80.0
80.6
u/l
0.05
209
1849
51
332
1.64
2.51
4.1
4.8
1.0
1.0
mmol/l
0.44
46
309
9
26
3.53
2.50
1.4
1.2
—
—
—
0
0
76
545
1.52
2.48
1.7
1.8
1.0
1.3
mg/l
0.84
62
425
61
419
1.57
2.41
1.6
1.5
—
—
—
0
0
46
295
1.66
2.40
1.9
2.0
—
—
—
0
0
16
71
2.32
2.38
1.6
1.6
—
—
—
0
0
129
1036
1.42
2.34
2.3
2.2
74.6
75.4
nmol/l
0.12
114
914
10
35
2.92
2.32
1.7
1.6
—
—
—
0
0
16
72
2.29
2.32
1.6
1.7
—
—
—
0
0
61
423
1.55
2.31
2.7
2.8
0.8
0.9
e6/l
0.16
36
242
10
36
2.84
2.22
1.4
1.7
—
—
—
0
0
16
74
2.22
2.18
1.3
1.2
—
—
—
0
0
51
345
1.57
2.15
31.2
21.3
1.4
1.3
inr
—
8
45
60
422
1.52
2.13
1.3
1.3
38.7
32.3
iu/ml
0.15
21
146
103
808
1.41
2.09
4.9
4.0
15.2
9.9
mg/mmol
0.29
68
513
91
702
1.42
2.02
3.5
3.1
0.2
0.5
e6/l
1.15
62
528
189
1646
1.38
2.01
3.7
3.3
46.3
50.6
u/l
0.27
180
1545
32
196
1.70
1.99
2.5
3.3
4.6
4.3
kpa
0.30
32
188
56
397
1.50
1.92
2.9
3.0
3.4
2.0
e6/l
0.37
32
220
128
1054
1.36
1.91
2.7
2.6
126.2
125.0
ug/l
0.02
117
960
47
322
1.54
1.89
5.0
4.7
30.4
31.8
%
0.44
31
209
8
28
2.90
1.87
1.0
1.2
—
—
—
0
0
11
46
2.44
1.87
1.6
1.7
—
—
—
0
0
10
40
2.55
1.85
1.7
1.6
—
—
—
0
0
32
201
1.66
1.83
3.1
2.8
79.4
63.0
ml/min/173m2
—
10
85
5
12
4.22
1.83
1.6
1.1
—
—
—
0
0
12
54
2.27
1.76
1.7
1.6
—
—
—
0
0
20
112
1.84
1.69
4.6
2.9
25.2
24.7
mmol/l
0.40
20
106
80
624
1.38
1.64
2.3
2.1
2.6
3.2
mg/l
1.26
63
538
15
77
2.00
1.62
1.3
1.2
—
—
—
0
0
98
792
1.35
1.61
2.9
3.1
1230.5
1289.4
ng/l
0.07
88
668
49
352
1.47
1.59
1.7
2.1
20.7
22.4
%
0.48
42
309
14
71
2.02
1.56
1.5
2.8
94.9
85.5
%
0.71
14
65
261
2437
1.43
1.56
5.3
4.7
6.1
6.0
mmol/l
0.62
236
2216
111
919
1.32
1.54
4.3
3.2
—
—
—
0
0
99
807
1.33
1.53
2.7
2.5
58.7
54.9
u/l
0.46
90
747
5
15
3.37
1.53
1.2
1.2
—
—
—
0
0
62
469
1.40
1.52
3.1
3.1
2.5
2.5
mmol/l
0.22
52
417
104
860
1.31
1.44
3.2
3.3
2.4
2.4
mmol/l
0.09
86
749
6
22
2.76
1.44
1.2
1.1
—
—
—
0
0
17
96
1.82
1.42
2.1
2.2
153.4
375.2
ug/l
1.64
17
89
45
326
1.44
1.40
6.3
6.7
103.9
104.0
mmol/l
0.03
45
319
54
405
1.40
1.40
1.4
1.3
37.6
12.4
u/ml
0.59
12
158
5
17
2.97
1.36
1.6
1.7
—
—
—
0
0
264
2489
1.39
1.31
22.1
14.7
22.1
23.7
mg/l
0.37
232
1987
39
280
1.45
1.28
9.2
7.5
1.3
1.4
mmol/l
0.04
30
228
14
77
1.86
1.27
1.4
1.2
—
—
—
0
0
8
36
2.25
1.25
1.5
1.5
—
—
—
0
0
13
71
1.87
1.21
2.5
2.5
82.9
78.4
ug/min
—
8
41
245
2294
1.32
1.19
6.1
4.6
1.9
2.5
mu/l
0.58
228
2081
31
217
1.48
1.17
7.3
7.0
1.8
1.3
mmol/l
0.81
31
209
0
35
0.00
1.16
0.0
1.5
—
—
—
0
0
0
36
0.00
1.14
0.0
1.5
—
—
—
0
0
11
58
1.93
1.13
1.0
1.2
—
—
—
0
0
28
194
1.49
1.11
2.4
3.2
74.2
79.1
ng/l
0.19
23
172
5
21
2.40
1.09
3.6
2.1
—
—
—
0
0
12
68
1.80
1.02
2.0
1.7
—
—
—
0
0
25
173
1.48
1.01
5.2
2.7
5.2
5.2
kpa
0.08
25
160
38
285
1.38
1.01
3.5
4.3
3.2
47.7
ug/l
0.96
31
237
169
1533
1.22
0.99
3.6
3.0
—
—
—
0
0
23
157
1.50
0.99
1.3
1.4
—
—
—
0
0
18
116
1.59
0.99
1.3
1.3
—
—
—
0
0
5
23
2.19
0.98
1.8
1.3
—
—
—
0
0
5
23
2.19
0.98
2.2
1.7
—
—
—
0
0
7
36
1.97
0.97
1.6
1.8
—
—
—
0
0
7
36
1.97
0.97
1.7
1.7
—
—
—
0
0
265
2532
1.31
0.93
5.6
5.1
2.6
2.7
mmol/l
1.08
238
2318
29
211
1.41
0.92
3.7
3.7
1.2
1.2
mmol/l
0.55
29
192
6
28
2.16
0.92
2.5
3.7
—
—
—
0
0
115
1012
1.22
0.89
4.3
3.9
27.3
42.0
ng/l
1.26
86
731
248
2356
1.26
0.87
7.4
6.1
41.0
40.3
mmol/mol
0.52
230
2186
23
162
1.45
0.87
6.5
6.3
23.6
24.9
mmol/l
0.75
23
162
6
31
1.95
0.85
1.7
1.9
—
—
—
0
0
6
31
1.95
0.85
1.2
1.2
—
—
—
0
0
10
57
1.78
0.84
1.4
1.4
—
—
—
0
0
72
607
1.24
0.84
1.6
1.6
20.2
21.2
nmol/l
0.25
59
506
8
46
1.76
0.83
1.5
1.5
—
—
—
0
0
40
314
1.31
0.82
11.6
7.2
—
—
—
0
0
81
695
1.22
0.80
1.7
1.7
1.5
1.4
mmol/l
0.32
60
568
15
98
1.56
0.80
1.5
1.9
—
—
—
0
0
5
24
2.10
0.75
2.2
1.6
972.2
532.7
e6/l
—
5
19
275
2657
1.30
0.74
24.7
17.2
78.9
77.8
umol/l
0.27
275
2657
5
25
2.02
0.73
2.0
1.8
—
—
—
0
0
5
25
2.02
0.73
2.0
1.8
—
—
—
0
0
5
25
2.02
0.73
2.0
1.8
—
—
—
0
0
11
68
1.64
0.72
1.1
1.1
—
13.6
—
0
8
251
2404
1.23
0.71
4.5
4.1
1.3
1.3
mmol/l
0.36
221
2195
5
26
1.94
0.71
1.4
1.2
—
—
—
0
0
89
781
1.20
0.70
2.2
2.2
147.7
211.5
u/l
1.08
84
738
21
153
1.40
0.69
1.1
1.2
31.7
141.6
iu/ml
—
7
61
65
558
1.21
0.65
1.7
1.7
128571919.0
432.8
pmol/l
0.49
49
466
23
173
1.36
0.64
1.7
1.5
—
—
—
0
0
11
72
1.55
0.60
2.1
1.4
—
—
—
0
0
8
53
1.52
0.59
1.9
1.5
—
—
—
0
0
12
82
1.48
0.55
1.2
1.7
—
—
—
0
0
6
38
1.59
0.54
1.2
1.3
—
—
—
0
0
11
75
1.48
0.51
2.0
2.6
8.8
13.1
mg/l
1.61
11
70
274
2671
1.21
0.49
14.7
10.6
24.6
26.0
u/l
0.99
262
2579
266
2587
1.19
0.48
25.6
16.9
4.0
4.0
mmol/l
0.34
260
2523
255
2472
1.17
0.48
5.1
4.6
1.4
1.5
mmol/l
0.65
229
2261
256
2483
1.17
0.47
5.1
4.6
4.5
4.6
mmol/l
0.72
230
2292
59
520
1.17
0.45
3.2
2.9
0.8
0.8
ug/l
0.18
39
329
10
69
1.46
0.45
1.1
1.2
—
8.7
—
0
13
62
550
1.16
0.44
1.4
1.3
0.9
1.3
u/ml
0.59
11
146
29
241
1.22
0.42
2.4
2.4
6.9
7.8
ug/l
0.14
29
207
10
71
1.42
0.39
1.5
1.3
—
—
—
0
0
132
1243
1.11
0.37
5.2
3.8
0.0
0.0
estimate
0.00
14
240
61
675
0.88
0.36
6.0
4.1
0.0
0.0
estimate
0.00
17
244
6
41
1.47
0.36
1.5
1.4
—
—
—
0
0
6
41
1.47
0.36
1.5
1.4
—
—
—
0
0
6
41
1.47
0.36
1.5
1.4
—
—
—
0
0
6
43
1.40
0.35
1.7
1.7
—
—
—
0
0
130
1226
1.10
0.35
6.5
5.1
0.0
0.0
estimate
0.00
17
246
10
73
1.38
0.35
2.6
3.3
—
1.3
—
0
8
245
2390
1.12
0.31
20.4
13.6
79.6
80.2
ml/min/173m2
0.19
216
1984
7
55
1.28
0.30
1.0
1.2
—
—
—
0
0
91
969
0.91
0.27
5.3
3.9
—
—
—
0
0
128
1219
1.08
0.27
5.0
3.8
0.0
0.0
estimate
0.00
17
252
10
78
1.29
0.24
1.9
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
3.9
—
—
—
0
0
0
10
0.00
0.21
0.0
3.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.4
—
103.1
—
0
12
19
219
0.86
0.21
2.4
2.1
—
—
—
0
0
23
202
1.15
0.21
2.0
1.8
—
—
—
0
0
94
894
1.07
0.20
5.3
4.9
3.9
2.7
ug/l
0.42
81
797
6
51
1.18
0.19
1.2
1.2
—
—
—
0
0
75
714
1.07
0.16
4.2
4.4
23.3
21.4
%
0.62
40
332
18
200
0.89
0.13
2.2
1.9
—
—
—
0
0
10
85
1.18
0.12
2.8
2.0
—
—
—
0
0
34
317
1.08
0.12
1.2
1.4
—
—
—
0
0
5
64
0.78
0.08
1.0
1.5
—
—
—
0
0
7
67
1.05
0.08
3.1
2.0
—
—
—
0
0
11
119
0.92
0.04
1.1
1.0
—
—
—
0
0
29
285
1.02
0.00
4.2
3.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
24.4
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
1.3
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
0.00
0.0
1.0
—
147.5
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
7
0.00
0.00
0.0
2.6
—
116.9
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
0.00
1.6
1.5
—
—
—
0
0
6
69
0.87
0.00
1.3
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_NASOPHARYNX and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_NASOPHARYNX | 1.468 [1.14, 1.89] | 0.003 |
| Birth year | 0.988 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 99 out of 608 females with CD2_BENIGN_NASOPHARYNX died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_NASOPHARYNX | 1.524 [1.23, 1.89] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 145 out of 638 males with CD2_BENIGN_NASOPHARYNX died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_NASOPHARYNX.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.144% | 0.226% |
| 5 | 0.644% | 1.578% |
| 10 | 1.517% | 4.198% |
| 15 | 2.925% | 8.015% |
| 20 | 5.201% | 13.646% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_NASOPHARYNX – Benign neoplasm: Nasopharynx
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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