Osteomalacia

M13_OSTEOMALACIA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M83
  • Hospital discharge: ICD-9 2682A
  • Hospital discharge: ICD-8 2652
  • Cause of death: ICD-10 M83
  • Cause of death: ICD-9 2682A
  • Cause of death: ICD-8 2652

2 out of 7 registries used, show all original rules.

317

4. Check minimum number of events

None

317

5. Include endpoints

None

317

6. Filter based on genotype QC (FinnGen only)

317

Control definitions (FinnGen only)

Control exclude
M13_OSTEOCHONDRO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M80-M85
Name in latin
Osteomalacia adultorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2358 1342 1003
Only index persons 2066 1151 915
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.03
Only index persons 0.04 0.04 0.03
Median age at first event (years)
Whole population 45.50 47.04 43.34
Only index persons 43.40 44.63 41.87

-FinnGen-

Key figures

All Female Male
Number of individuals 317 208 109
Unadjusted period prevalence (%) 0.06 0.07 0.05
Median age at first event (years) 45.39 45.56 45.07

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
283
Matched controls
2828
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M83.2
ICD-10 Finland
Adult osteomalacia due to malabsorption
+∞
144.5
126
*
M83.9
ICD-10 Finland
Adult osteomalacia, unspecified
+∞
53.9
50
*
M83.5
ICD-10 Finland
Other drug-induced osteomalacia in adults
+∞
30.8
29
*
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
6.6
30.2
87
178
M83.8
ICD-10 Finland
Other adult osteomalacia
+∞
21.1
20
*
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
5.1
19.4
67
163
M83.4
ICD-10 Finland
Aluminium bone disease
+∞
17.9
17
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
3.5
15.9
86
312
M83.0
ICD-10 Finland
Puerperal osteomalacia
+∞
15.8
15
*
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
10.0
14.6
29
32
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
6.0
14.5
41
78
M83.3
ICD-10 Finland
Adult osteomalacia due to malnutrition
+∞
13.6
13
*
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
5.9
13.1
37
70
S83.5
ICD-10 Finland
Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
6.8
12.7
32
52
M83.1
ICD-10 Finland
Senile osteomalacia
+∞
12.6
12
*
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
3.7
12.5
58
183
S83.2
ICD-10 Finland
Tear of meniscus, current
4.3
10.3
39
102
NGE35
NOMESCO Finland
Plastic repair of ligament of knee not using prosthetic material, anterior cruciate, arthroscopic
8.4
10.3
22
28
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
10.2
155
979
N02AX02
ATC
tramadol; systemic, rectal
2.3
9.7
136
822
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.4
8.9
92
474
ZXA00
NOMESCO Finland
Right side
2.4
8.7
85
427
M25.5
ICD-10 Finland
Pain in joint
2.3
8.3
97
530
N02BE01
ATC
paracetamol; systemic, rectal
2.6
7.8
247
2054
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
25.8
7.6
10
*
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
82.2
7.5
8
*
M81.9
ICD-10 Finland
Osteoporosis, unspecified
11.3
7.4
13
12
26520
ICD-8 Finland
Vitamin D deficiency, Osteomalacia
+∞
7.3
7
*
X58
ICD-10 Finland
Exposure to other specified factors
2.7
7.3
51
211
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.0
7.2
42
157
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
6.6
7.1
17
27
M01AH05
ATC
etoricoxib; oral
2.0
7.0
181
1336
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
4.1
7.0
26
68
S18
ICPC
Laceration/cut
2.0
7.0
119
753
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
7.5
6.8
15
21
A12AA04
ATC
calcium carbonate; oral
17.2
6.8
10
6
M79.6
ICD-10 Finland
Pain in limb
2.0
6.7
106
646
ZXA05
NOMESCO Finland
Left side
2.2
6.6
80
437
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
4.5
6.4
21
49
N03AX16
ATC
pregabalin; oral
2.1
6.0
76
422

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3032080) INR in Blood by Coagulation assay
151
901
2.29
11.72
6.1
8.2
inr
1.2
1.2
0.33
45
290
(3013826) Glucose [Moles/volume] in Serum or Plasma
202
1445
2.10
9.00
5.5
4.7
mmol/l
6.6
6.6
0.14
192
1342
(3019198) Lymphocytes [#/volume] in Blood
182
1312
1.91
7.27
5.8
5.8
e9/l
1.9
2.0
0.35
165
1173
(3013115) Eosinophils [#/volume] in Blood
183
1323
1.91
7.23
5.8
6.1
e9/l
0.2
0.2
0.13
164
1179
(3006315) Basophils [#/volume] in Blood
178
1279
1.89
7.13
5.8
5.8
e9/l
0.0
0.0
0.05
160
1119
(3001604) Monocytes [#/volume] in Blood
177
1276
1.88
6.95
5.7
5.8
e9/l
0.5
0.6
1.59
159
1116
(42870588) Differential panel, method unspecified - Blood
125
810
1.90
6.82
5.3
5.4
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
55
273
2.23
6.20
1.8
1.5
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
37
159
2.50
5.75
1.6
1.5
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
107
692
1.82
5.68
3.6
2.7
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
167
1235
1.74
5.57
5.8
5.7
%
30.3
28.9
0.99
162
1164
(3018010) Neutrophils/100 leukocytes in Blood
165
1220
1.74
5.47
5.6
5.5
%
55.7
56.7
0.54
160
1157
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
161
1187
1.72
5.36
4.9
4.0
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
161
1190
1.72
5.28
5.7
5.6
%
2.8
2.8
0.13
155
1111
(3013707) Erythrocyte sedimentation rate by Westergren method
236
1948
1.83
5.17
4.9
3.9
mm/h
11.0
10.7
0.12
226
1794
(3019069) Monocytes/100 leukocytes in Blood
161
1200
1.69
5.05
5.9
5.9
%
8.5
8.3
0.43
156
1136
(40760892) CBC W Ordered Manual Differential panel - Blood
96
626
1.77
4.85
4.0
5.0
—
—
—
0
0
(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum
8
7
11.68
4.81
1.6
1.7
ug/l
48.4
85.2
—
8
7
(3022096) Basophils/100 leukocytes in Blood
154
1145
1.67
4.80
5.9
5.7
%
0.7
0.7
0.64
149
1073
(3026493) Urate [Moles/volume] in Serum or Plasma
99
654
1.75
4.77
3.2
2.5
umol/l
333.4
8103.1
3.33
82
575
(3018418) pH of Serum or Plasma
105
713
1.71
4.55
5.8
3.7
ph
7.4
7.4
1.66
17
137
(3037467) Urinalysis macro (dipstick) panel - Urine
218
1796
1.68
4.39
4.8
4.0
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
25
103
2.55
4.25
1.6
1.5
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
25
104
2.52
4.17
1.6
1.5
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
25
104
2.52
4.17
1.6
1.5
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
43
231
2.00
3.93
5.4
9.4
mmol/l
1.5
1.1
0.46
35
189
(3019060) Gas panel - Arterial blood
29
134
2.28
3.87
3.3
7.7
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
185
1489
1.58
3.86
9.2
9.2
e9/l
3.8
4.0
1.25
164
1312
(3027944) Amphetamines [Presence] in Urine
24
104
2.41
3.69
1.7
1.5
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
110
791
1.60
3.69
2.8
2.2
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
23
99
2.43
3.59
1.5
1.5
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
165
1308
1.55
3.58
5.1
3.4
estimate
0.0
0.0
0.00
35
245
(3023368) Bacteria identified in Blood by Culture
86
588
1.63
3.52
5.6
3.9
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
291
2663
2.13
3.49
18.4
12.1
mg/l
22.3
21.0
0.30
240
2053
(3021601) Nitrite [Presence] in Urine by Test strip
165
1314
1.53
3.47
6.3
4.7
estimate
0.0
0.0
0.00
36
244
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
107
775
1.57
3.44
3.1
2.5
u/l
52.4
55.7
0.77
101
721
(3002582) Erythrocytes [#/volume] in Urine
103
740
1.58
3.43
3.3
2.9
e6/l
71.4
40.7
0.25
77
554
(3009261) Glucose [Presence] in Urine by Test strip
166
1327
1.53
3.41
5.1
3.4
estimate
0.0
0.0
0.00
38
235
(1001926) Buprenorphine [Presence] in Urine by Screen method
20
86
2.41
3.15
1.6
1.5
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
71
475
1.64
3.14
1.9
1.7
pmol/l
447.7
443.9
0.04
58
402
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
73
492
1.63
3.14
1.4
1.3
iu/ml
24.2
34.0
0.53
28
151
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
85
596
1.58
3.10
2.7
2.1
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
74
502
1.62
3.10
2.8
2.4
e6/l
6.9
5.2
0.65
66
441
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
134
1040
1.50
3.07
3.0
2.2
nmol/l
75.0
76.4
0.25
126
940
(3018095) Leukocytes [#/volume] in Urine
117
890
1.50
2.93
3.9
3.4
e6/l
108.0
74.9
0.33
82
607
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
228
1984
1.53
2.91
9.3
7.4
u/l
74.8
77.6
0.56
220
1864
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
71
485
1.60
2.88
1.4
1.2
u/ml
22.0
7.0
0.49
28
195
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
12
42
2.93
2.78
1.5
1.1
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
14
54
2.67
2.74
1.2
1.3
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
28
148
1.98
2.71
5.4
2.3
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
16
67
2.46
2.68
2.6
2.1
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
113
871
1.46
2.59
4.0
3.0
—
—
—
0
0
(3044889) 12 lead EKG panel
210
1819
1.46
2.56
4.2
3.5
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
94
704
1.48
2.48
6.2
3.5
estimate
0.0
0.0
0.50
35
242
(3023520) Reticulocytes [#/volume] in Blood
29
161
1.88
2.45
2.3
2.7
e9/l
69.4
69.7
0.02
23
124
(3021788) Differential panel - Synovial fluid
10
34
3.00
2.43
1.5
1.3
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
63
436
1.56
2.40
4.8
3.6
ng/l
160.7
114.5
0.20
45
327
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
14
58
2.48
2.40
1.3
1.2
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
82
602
1.49
2.38
5.7
3.3
—
—
—
0
0
(37020300) Entamoeba histolytica DNA [Presence] in Stool by NAA with probe detection
5
8
6.33
2.38
1.4
1.0
—
—
—
0
0
(3020891) Body temperature
19
92
2.13
2.32
7.1
4.5
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
129
1036
1.41
2.32
5.5
3.4
—
—
—
0
0
(4024509)
6
13
4.68
2.28
1.5
1.3
—
—
—
0
0
(3000570) Elastase.pancreatic [Mass/mass] in Stool
18
86
2.16
2.27
1.4
1.4
ug/g
314.3
284.9
—
10
49
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
144
1186
1.39
2.21
9.3
6.4
mmol/l
1.2
1.2
0.06
132
1008
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
115
913
1.41
2.18
4.5
3.3
ng/l
23.6
33.7
0.72
72
587
(36304419) Bacteria [Presence] in Urine
88
666
1.44
2.18
3.0
2.7
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
42
270
1.64
2.17
29.1
17.4
inr
1.2
1.2
0.00
11
44
(3002173) Hemoglobin [Mass/volume] in Arterial blood
32
193
1.73
2.09
6.3
10.5
g/l
127.9
121.4
0.70
32
186
(3019309) Folate [Moles/volume] in Red Blood Cells
55
384
1.52
2.02
2.3
1.6
nmol/l
1457.3
1227.8
0.40
46
290
(3003338) MCHC [Mass/volume]
254
2322
1.47
2.02
22.2
15.8
g/l
332.7
332.7
0.05
254
2316
(3009508) Creatinine [Moles/volume] in Urine
96
748
1.41
2.01
3.2
3.0
mmol/l
8.1
8.0
0.03
89
625
(3030467) Casts [#/volume] in Urine by Automated count
88
676
1.42
1.99
3.1
2.8
e6/l
0.4
0.5
0.41
65
493
(3000991) Gas panel - Venous blood
29
173
1.74
1.98
7.2
8.0
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
13
58
2.29
1.93
1.5
1.4
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
156
1322
1.35
1.93
6.9
6.4
umol/l
10.4
10.7
0.24
151
1255
(3042936) Bacteria identified in Isolate by Culture
48
331
1.53
1.87
2.5
2.0
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
75
567
1.42
1.85
6.7
3.7
kg/l
1.0
1.0
—
8
76
(3001122) Ferritin [Mass/volume] in Serum or Plasma
138
1155
1.34
1.83
3.1
2.7
ug/l
110.4
117.1
0.13
131
1074
(3019897) Erythrocyte distribution width [Ratio] by Automated count
8
29
2.80
1.80
2.9
2.1
%
13.1
13.3
—
8
29
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
17
88
1.98
1.78
1.8
2.2
u/l
8351.3
3153.5
—
8
35
(40761535) Cells panel - Urine sediment
33
211
1.63
1.76
5.3
3.4
—
—
—
0
0
(3023103) Potassium [Moles/volume] in Serum or Plasma
285
2687
1.60
1.76
20.8
13.6
mmol/l
4.0
4.0
0.08
280
2610
(21494890) Protein electrophoresis panel - 24 hour Urine
7
24
2.96
1.73
2.1
2.0
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
226
2046
1.36
1.72
4.7
3.9
pmol/l
14.8
14.6
0.50
213
1872
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
114
934
1.34
1.72
2.1
1.9
pmol/l
91.6
97.7
0.83
62
473
(40768797) Stomach Pathology biopsy report
50
355
1.48
1.71
1.3
1.2
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
139
1174
1.33
1.70
10.5
8.4
e9/l
0.0
0.0
0.65
116
972
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
37
247
1.56
1.67
2.8
3.0
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
53
383
1.46
1.66
1.5
1.3
titre
286.2
540.5
1.45
13
82
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
113
932
1.33
1.61
2.6
3.1
u/l
29.9
33.6
1.01
108
896
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
6
20
3.04
1.59
1.3
1.2
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
6
20
3.04
1.59
1.3
1.2
—
—
—
0
0
(4268621)
8
33
2.46
1.55
1.9
2.1
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
8
33
2.46
1.55
1.8
1.5
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
8
33
2.46
1.55
1.8
1.5
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
8
33
2.46
1.55
1.8
1.5
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
8
33
2.46
1.55
1.8
1.5
—
—
—
0
0
(1616796) Gas panel - Central venous blood
10
44
2.31
1.55
5.6
2.4
—
—
—
0
0
(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma
5
15
3.37
1.53
4.0
4.3
nmol/l
60.8
84.1
—
5
15
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
49
355
1.45
1.52
1.8
1.8
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
75
586
1.37
1.52
1.9
1.7
mg/l
0.7
1.1
1.21
51
453
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
43
305
1.47
1.48
3.1
2.2
%
24.1
24.2
0.01
36
267
(3022621) pH of Urine by Test strip
27
174
1.60
1.43
2.6
2.6
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
20
119
1.73
1.41
7.1
6.9
mmol/l
25.2
25.0
0.11
20
119
(3025130) Human papilloma virus identified in Specimen
9
40
2.29
1.41
2.3
2.0
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
9
40
2.29
1.41
2.8
1.3
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
11
53
2.11
1.40
1.5
1.6
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
269
2533
1.41
1.39
15.8
11.1
ml/min/173m2
85.4
84.3
0.34
228
2079
(3011391) Calcitriol [Moles/volume] in Serum or Plasma
5
17
2.97
1.36
1.4
1.2
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
293
2806
1.58
1.36
16.5
11.3
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
9
42
2.18
1.35
4.0
1.6
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
126
1078
1.28
1.33
2.0
2.0
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
91
746
1.31
1.33
3.8
3.0
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
101
840
1.30
1.33
4.0
3.1
mmol/l
2.4
2.4
0.08
95
741
(3005988) Vibrio sp identified in Specimen by Organism specific culture
8
34
2.39
1.30
1.8
1.5
—
—
—
0
0
(3026782) Osmolality of Urine
59
455
1.36
1.30
3.1
2.6
mosm/kgh2o
545.4
554.8
0.12
50
386
(3016244) Insulin [Units/volume] in Serum or Plasma
5
18
2.80
1.29
1.4
2.6
mu/l
21.9
21.4
—
5
18
(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
15
85
1.80
1.25
8.1
2.3
g/l
6.9
7.4
—
10
69
(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
15
85
1.80
1.25
8.1
2.3
g/l
3.6
3.7
—
10
65
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
15
85
1.80
1.25
8.1
2.3
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
9
45
2.03
1.24
1.3
1.2
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
9
45
2.03
1.24
1.1
1.1
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
31
214
1.50
1.24
2.8
3.0
ml/min/173m2
73.1
65.9
0.30
15
91
(3023323) Follitropin [Units/volume] in Serum or Plasma
22
141
1.60
1.21
1.5
1.3
iu/l
29.6
23.9
0.37
22
124
(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation
11
57
1.96
1.18
1.7
1.6
pmol/l
189.1
244.6
0.81
11
52
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
282
2693
1.43
1.18
4.7
4.7
mmol/l
2.8
2.9
1.31
272
2524
(4035726)
32
225
1.47
1.18
1.4
1.3
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
19
118
1.65
1.18
1.2
1.1
—
—
—
0
0
(3012544) pH of Venous blood
30
209
1.48
1.16
4.0
3.3
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
278
2651
1.40
1.15
4.3
4.3
mmol/l
4.7
4.8
1.02
269
2494
(3030905) Polymorphonuclear cells [#/volume] in Blood
8
40
2.03
1.13
1.9
3.6
e9/l
5.4
4.9
—
8
40
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
40
297
1.40
1.11
12.1
6.2
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
15
89
1.72
1.09
2.1
1.9
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
86
718
1.27
1.08
3.7
4.0
mg/mmol
10.6
8.0
0.18
60
451
(3024522) Salmonella sp identified in Specimen by Organism specific culture
7
33
2.15
1.06
1.9
1.5
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
9
47
1.94
1.03
1.1
1.2
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
9
47
1.94
1.03
12.7
4.8
—
—
—
0
0
(3027315) Oxygen [Partial pressure] in Blood
9
47
1.94
1.03
7.8
2.8
kpa
8.6
8.7
—
9
47
(3013290) Carbon dioxide [Partial pressure] in Blood
9
47
1.94
1.03
7.8
2.9
kpa
5.3
5.0
—
9
47
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
56
446
1.31
1.01
3.6
2.6
mmol/l
2.4
2.4
0.10
49
394
(3042111) Morphology [Interpretation] in Bone marrow Narrative
7
35
2.02
1.00
1.3
1.8
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
81
678
1.26
1.00
3.7
3.2
mg/l
783.0
258.1
0.32
57
426
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
11
61
1.83
0.99
1.2
1.2
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
276
2642
1.35
0.99
4.1
4.3
mmol/l
1.4
1.5
1.05
267
2477
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
18
116
1.58
0.99
1.6
1.4
—
—
—
0
0
(3016018) Differential panel - Cerebral spinal fluid
5
23
2.19
0.98
1.4
1.1
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
41
313
1.36
0.98
1.6
1.5
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
76
634
1.26
0.96
3.7
4.3
ug/l
1.6
2.5
0.98
70
579
(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
15
93
1.64
0.95
1.6
1.8
—
256.0
—
0
5
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
16
101
1.62
0.95
1.5
1.5
—
—
—
0
0
(3022145) Colonoscopy Study observation
39
297
1.36
0.95
1.2
1.3
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
31
227
1.41
0.95
3.7
3.1
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
268
2560
1.30
0.93
4.4
4.3
mmol/l
6.0
5.9
0.41
256
2386
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
51
406
1.31
0.93
2.5
2.4
e6/l
0.5
1.1
1.51
24
229
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
21
143
1.50
0.92
1.0
1.0
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
6
28
2.16
0.92
1.5
1.1
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
74
619
1.26
0.92
1.3
1.2
u/ml
0.5
1.2
2.60
19
179
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
8
42
1.93
0.89
2.0
4.2
%
63.6
58.5
—
8
42
(3014148) Varicella zoster virus Ab [Titer] in Serum
6
30
2.02
0.87
1.2
1.2
—
—
—
0
0
(3002032) Base excess in Venous blood by calculation
28
205
1.40
0.87
4.1
3.2
mmol/l
2.6
2.2
0.24
22
163
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
47
374
1.30
0.86
2.8
2.6
e6/l
1.5
2.6
1.07
21
198
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
267
2558
1.28
0.84
3.9
3.9
mmol/l
1.4
1.3
0.85
259
2390
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
8
47
1.72
0.81
2.0
1.3
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
8
48
1.68
0.79
2.0
1.4
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
13
82
1.61
0.79
1.8
1.8
—
—
—
0
0
(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood
0
26
0.00
0.79
0.0
1.8
—
699.7
—
0
12
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
27
0.00
0.78
0.0
1.0
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
14
91
1.56
0.76
1.1
1.2
—
—
—
0
0
(40758558) Short blood count panel - Blood
75
643
1.22
0.75
6.5
6.9
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
15
100
1.52
0.74
2.0
2.0
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
9
55
1.65
0.74
1.8
1.6
—
—
—
0
0
(4306422)
7
38
1.86
0.74
1.1
1.3
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
256
2451
1.23
0.74
5.4
4.6
mu/l
1.8
2.4
0.57
243
2266
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
13
84
1.57
0.73
1.5
1.7
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
259
2484
1.23
0.72
15.7
12.8
%
39.7
40.5
0.88
192
1931
(3010421) pH of Blood
9
57
1.60
0.71
7.9
2.8
ph
7.4
7.4
—
9
47
(1002224) Polysomnography panel
9
145
0.61
0.71
1.0
1.1
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
45
367
1.26
0.70
1.8
1.9
%
1.5
1.4
0.51
37
326
(3045424) Erythrocytes [Presence] in Urine
7
42
1.68
0.69
1.3
1.4
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
5
28
1.80
0.66
1.6
1.3
—
—
—
0
0
(4062490)
5
28
1.80
0.66
1.4
1.3
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
71
616
1.20
0.63
3.2
3.1
ng/l
994.8
971.9
0.03
62
514
(3019225) pH of Specimen
28
218
1.31
0.62
5.6
4.5
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
5
30
1.68
0.61
2.6
1.2
—
—
—
0
0
(4034850)
12
80
1.52
0.60
19.9
9.5
—
—
—
0
0
(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood
12
80
1.52
0.60
3.2
9.9
%
2.0
1.5
0.64
12
74
(3025149) Bordetella pertussis IgA Ab [Units/volume] in Serum
0
20
0.00
0.60
0.0
1.1
—
5.6
—
0
5
(3023430) Cat dander IgE Ab [Units/volume] in Serum
0
21
0.00
0.60
0.0
1.0
—
3.5
—
0
6
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
21
0.00
0.60
0.0
9.1
—
0.6
—
0
21
(3020491) Glucose [Moles/volume] in Blood
0
21
0.00
0.60
0.0
2.2
—
6.3
—
0
16
(3007164) IgA [Mass/volume] in Serum or Plasma
66
572
1.19
0.60
1.6
1.4
g/l
2.0
2.4
1.12
39
365
(3051611) Lipemic interference index of Serum or Plasma
0
22
0.00
0.59
0.0
2.5
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
26
202
1.31
0.59
1.5
1.5
—
—
—
0
0
(3047181) Lactate [Moles/volume] in Blood
10
64
1.58
0.59
2.8
12.7
mmol/l
1.2
1.2
—
10
55
(3002385) Erythrocyte distribution width [Ratio]
236
2261
1.17
0.57
19.0
14.9
%
13.7
13.6
1.18
236
2229
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
60
518
1.20
0.57
4.0
4.0
%
22.5
21.7
0.11
27
228
(3011985) Renin [Units/volume] in Plasma
6
37
1.63
0.56
1.3
1.1
mu/l
83.0
52.9
—
6
32
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
6
37
1.63
0.56
1.0
1.5
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
21
160
1.33
0.55
1.5
1.2
u/ml
80.0
310.9
0.92
21
148
(3038177) Helicobacter pylori Ab [Presence] in Serum
6
38
1.59
0.54
1.2
1.1
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
14
100
1.42
0.52
8.6
15.0
—
—
—
0
0
(3046279) Procalcitonin [Mass/volume] in Serum or Plasma
12
83
1.46
0.52
1.6
1.8
ug/l
3.1
4.8
0.16
12
76
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
18
135
1.35
0.52
1.6
1.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
16
213
0.74
0.52
1.4
1.4
—
—
—
0
0
(3013512) EKG study
79
705
1.16
0.51
3.2
3.5
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
31
253
1.25
0.50
1.6
1.7
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
198
1884
1.14
0.49
3.4
3.1
u/l
47.7
43.6
0.33
192
1781
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
31
254
1.24
0.49
1.7
1.7
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
7
46
1.53
0.48
5.1
2.4
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
27
218
1.26
0.48
1.1
1.2
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
7
47
1.50
0.48
1.4
1.9
—
—
—
0
0
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
5
82
0.60
0.46
1.2
1.5
—
0.0
—
0
16
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
51
1.38
0.44
1.0
1.4
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
7
51
1.38
0.44
4.6
1.5
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
5
31
1.62
0.43
1.2
1.2
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
8
56
1.44
0.43
1.1
1.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
8
56
1.44
0.43
1.1
1.1
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
8
56
1.44
0.43
1.5
1.8
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
5
32
1.57
0.42
1.2
1.3
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
5
33
1.52
0.41
1.2
1.5
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
5
33
1.52
0.41
4.0
3.4
nmol/l
13.4
3.7
—
5
33
(3051651) Icteric interference index of Serum or Plasma
0
15
0.00
0.41
0.0
2.6
—
—
—
0
0
(3037692) Legionella sp identified in Specimen by Organism specific culture
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
(3010503) CD19 cells [#/volume] in Blood
0
16
0.00
0.41
0.0
1.4
—
0.2
—
0
16
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
192
1836
1.12
0.40
3.1
3.3
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
13
97
1.35
0.40
2.2
2.2
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
24
290
0.81
0.39
3.8
4.3
%
32.4
32.7
0.03
18
196
(3041067) Sjogrens syndrome-A extractable nuclear 52kD Ab [Units/volume] in Serum
0
19
0.00
0.39
0.0
1.2
—
79.0
—
0
6
(3025018) Bordetella pertussis Ab [Titer] in Serum
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
(40768443) Skin Pathology biopsy report
12
89
1.36
0.38
1.7
1.2
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
252
2452
1.14
0.37
5.6
5.3
mmol/mol
39.6
39.3
0.22
242
2310
(3000492) Spirometry study
31
263
1.20
0.37
1.3
1.4
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
14
108
1.31
0.36
1.4
1.6
—
—
—
0
0
(3024928) Oxygen saturation in Venous blood
6
42
1.44
0.35
1.3
3.1
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
24
200
1.22
0.35
4.3
4.8
%
0.6
1.0
—
10
64
(3025941) Bacteria identified in Stool by Culture
19
154
1.25
0.34
1.2
1.2
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
6
44
1.37
0.34
1.0
1.4
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
39
341
1.16
0.34
2.4
2.2
ug/g
153.7
102.5
0.43
27
263
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
17
136
1.26
0.34
1.2
1.5
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
48
427
1.15
0.34
1.7
1.6
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
22
183
1.22
0.32
4.5
5.2
%
0.0
0.1
—
9
55
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
7
57
1.23
0.29
1.6
1.5
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
9
73
1.24
0.25
2.6
1.8
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
9
74
1.22
0.25
1.2
1.3
—
—
—
0
0
(4010399)
22
189
1.18
0.25
1.3
1.4
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
11
87
1.27
0.24
2.1
2.6
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
39
1.29
0.23
1.0
1.5
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
34
305
1.13
0.23
1.5
1.4
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
7
91
0.76
0.23
1.0
1.2
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
7
91
0.76
0.23
1.0
1.2
—
—
—
0
0
(40768793) Breast Pathology biopsy report
7
91
0.76
0.23
1.7
1.3
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
7
93
0.75
0.22
1.1
1.2
—
—
—
0
0
(3012110) Lysozyme [Mass/volume] in Serum or Plasma
10
79
1.27
0.22
1.8
2.5
mg/l
11.7
11.2
—
10
73
(3039000) Anion gap in Blood
5
40
1.25
0.22
3.8
17.8
mmol/l
10.2
10.6
—
5
35
(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay
5
40
1.25
0.22
1.4
1.6
u/l
56.6
18.4
—
5
35
(3018572) Chloride [Moles/volume] in Blood
5
40
1.25
0.22
3.8
17.9
mmol/l
103.6
105.3
—
5
35
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
40
364
1.11
0.21
2.0
2.1
—
—
—
0
0
(3028772) Osteocalcin [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
3.7
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
20
173
1.17
0.21
1.3
1.2
—
—
—
0
0
(3036071) Salmonella sp Ab [Titer] in Serum
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
3.8
—
674.2
—
0
12
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(3035880) pH of Pleural fluid
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
6
48
1.25
0.20
1.2
1.5
—
—
—
0
0
(3000012) Reticulocyte production index
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
(3025159) Blasts/100 leukocytes in Blood
20
174
1.16
0.20
4.6
5.2
%
0.2
0.1
—
6
47
(3017143) Hepatitis C virus Ab [Presence] in Serum
35
318
1.11
0.20
1.7
1.6
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
13
154
0.84
0.19
1.4
1.9
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
10
81
1.24
0.19
1.2
1.2
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
6
53
1.13
0.19
1.7
1.6
—
—
—
0
0
(3002256) Pathology report gross observation
36
329
1.11
0.18
1.1
1.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
30
272
1.11
0.17
1.8
1.8
—
—
—
0
0
(3007930) Methemoglobin/Hemoglobin.total in Blood
10
82
1.23
0.17
2.8
9.7
%
0.7
0.9
—
10
77
(3008898) HLA-B27 [Presence]
14
120
1.17
0.16
1.1
1.1
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
8
69
1.16
0.16
1.1
1.6
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
27
297
0.90
0.16
2.0
1.7
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
9
80
1.13
0.15
1.3
1.1
—
—
—
0
0
(3022313) Gas panel - Capillary blood
12
103
1.17
0.14
3.0
3.4
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
47
498
0.93
0.13
1.6
1.4
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
37
346
1.08
0.12
1.2
1.4
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
26
240
1.09
0.11
3.7
4.4
ug/l
77.4
25.7
0.30
21
192
(3002179) Metamyelocytes/100 leukocytes in Blood
20
182
1.11
0.11
3.3
4.9
%
1.8
0.5
—
6
43
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
68
706
0.95
0.10
1.6
1.6
mmol/l
1.4
1.4
0.07
58
595
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
5
44
1.14
0.10
1.4
1.2
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
5
44
1.14
0.10
1.4
1.2
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
5
47
1.06
0.09
1.4
1.2
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
14
155
0.90
0.09
1.1
1.4
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
7
64
1.10
0.08
1.4
1.5
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
7
65
1.08
0.08
1.1
1.3
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
36
378
0.95
0.08
2.6
2.8
ug/l
0.8
0.7
0.16
18
233
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
7
67
1.05
0.08
1.6
1.5
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
6
70
0.85
0.07
2.8
2.3
—
—
—
0
0
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
8
74
1.08
0.07
2.8
2.5
mg/l
1.7
1.4
—
8
68
(4094501)
8
76
1.05
0.07
1.1
1.1
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
8
78
1.03
0.07
1.0
1.1
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
33
314
1.06
0.07
1.8
3.0
umol/l
13.8
8.5
0.28
27
273
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
9
84
1.07
0.07
1.2
1.6
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
13
118
1.11
0.07
1.9
1.7
—
—
—
0
0
(3009343) pH of Capillary blood
15
138
1.09
0.06
2.6
3.5
—
7.4
—
0
17
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
19
202
0.94
0.05
1.1
1.2
iu/ml
396.0
121.5
—
6
80
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
12
110
1.09
0.05
2.7
2.3
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
15
140
1.07
0.04
2.7
3.4
kpa
5.8
5.1
—
10
127
(3003694) ABO and Rh group [Type] in Blood
77
756
1.02
0.04
1.4
1.4
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
13
121
1.08
0.04
3.5
3.3
—
—
—
0
0
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
12
129
0.93
0.03
2.1
1.9
mg/l
7.1
2.4
—
6
97
(1761868) Lipid panel - Serum or Plasma
104
1053
0.98
0.03
2.6
2.8
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
17
178
0.95
0.02
1.5
1.7
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
10
93
1.08
0.02
1.3
1.5
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
32
328
0.97
0.02
2.0
2.0
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
54
537
1.01
0.00
1.9
1.5
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
20
195
1.03
0.00
1.8
2.0
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
52
525
0.99
0.00
2.0
1.9
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
31
314
0.99
0.00
1.5
1.7
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
5
55
0.91
0.00
4.4
1.4
—
—
—
0
0
(3032057) Clostridioides difficile [Presence] in Stool
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
7
77
0.91
0.00
1.3
1.5
—
—
—
0
0
(3029396) Erythrocyte agglutination [Presence] in Blood
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(40761539) Cells [Type] in Urine sediment by Light microscopy
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(42868415) European tick borne encephalitis virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
7
77
0.91
0.00
1.3
1.2
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
6
65
0.92
0.00
1.2
1.5
—
—
—
0
0
(3012741) Chlamydophila pneumoniae IgA Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
7
77
0.91
0.00
1.3
1.5
—
—
—
0
0
(44806420)
0
6
0.00
0.00
0.0
3.2
—
—
—
0
0
(21494814) CD8 cells/100 lymphocytes in Specimen
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
5
54
0.92
0.00
1.0
2.6
u/ml
17.4
27.5
—
5
54
(3033799) Differential panel - Peritoneal fluid
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3041806) Other cells [#/volume] in Blood by Manual count
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
18
180
1.00
0.00
1.4
1.3
—
35.2
—
0
12
(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
6
65
0.92
0.00
1.2
1.5
—
—
—
0
0
(3024471) HLA-A [Type]
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010375) cycloSPORINE [Mass/volume] in Blood
0
8
0.00
0.00
0.0
36.4
—
110.5
—
0
8
(3052851) Hemolysis interference index of Serum or Plasma
7
69
1.01
0.00
1.6
2.9
—
—
—
0
0
(3024932) HLA-DR beta [Type]
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
6
64
0.94
0.00
4.3
4.4
—
—
—
0
0
(3003129) Base excess in Capillary blood by calculation
0
6
0.00
0.00
0.0
1.0
—
3.9
—
0
6
(3020073) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Specimen
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(4133840)
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016228) CD19 cells/100 cells in Blood
0
6
0.00
0.00
0.0
1.3
—
8.2
—
0
6
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
7
77
0.91
0.00
1.3
1.5
—
—
—
0
0
(3035457) Cefaclor IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(37021550) Renin [Units/volume] in Plasma --upright
0
7
0.00
0.00
0.0
1.7
—
135.3
—
0
7
(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3008536) Aspergillus sp Ab [Presence] in Serum
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(42868418) European tick borne encephalitis virus IgG Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
7
77
0.91
0.00
1.3
1.5
—
—
—
0
0
(3038769) Chlamydophila pneumoniae IgG Ab [Units/volume] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
25.1
—
0
6
(3044007) Cell count panel - Peritoneal fluid
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay
8
83
0.96
0.00
1.0
1.1
—
2.4
—
0
12
(3025378) Microscopic observation [Identifier] in Cervix by Cyto stain
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000213) Normetanephrine [Moles/time] in 24 hour Urine
0
8
0.00
0.00
0.0
1.3
—
2.1
—
0
8
(3027231) Wheat IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
9
91
0.99
0.00
1.2
1.5
—
—
—
0
0
(3015076) Soybean IgE Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009876) Amylase isoenzyme 3 panel - Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(44806071)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_OSTEOMALACIA and mortality.

Females

Parameter HR [95% CI] p-value
M13_OSTEOMALACIA 1.361 [1.13, 1.63] 0.001
Birth year 0.999 [0.99, 1.01] 0.78

During the follow-up period (1.1.1998 — 31.12.2019), 159 out of 1044 females with M13_OSTEOMALACIA died.

Males

Parameter HR [95% CI] p-value
M13_OSTEOMALACIA 1.341 [1.1, 1.63] 0.003
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 112 out of 827 males with M13_OSTEOMALACIA died.

Mortality risk

Mortality risk for people of age

years, who have M13_OSTEOMALACIA.

N-year risk Females Males
1 0.08% 0.194%
5 0.877% 1.441%
10 2.346% 3.536%
15 4.516% 6.561%
20 7.848% 11.19%

Relationships between endpoints

Index endpoint: M13_OSTEOMALACIA – Osteomalacia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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