No definition available.
Drug-induced adrenocortical insufficiency
DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
599 |
4. Check minimum number of eventsNone |
599 |
5. Include endpointsNone |
599 |
6. Filter based on genotype QC (FinnGen only) |
599 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Drug-induced adrenocortical insufficiency
based on the number of shared cases.
Similar with more cases:
- Adrenocortical insufficiency
- Other disorders of adrenal gland
- Exclusions for E4_PCOS_BROAD
- Disorders of other endocrine glands
- Autoimmune diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2471 | 1595 | 868 |
| Only index persons | 2275 | 1493 | 782 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.02 |
| Only index persons | 0.05 | 0.05 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 57.01 | 57.43 | 56.23 |
| Only index persons | 58.04 | 57.88 | 58.36 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 599 | 408 | 191 |
| Unadjusted period prevalence (%) | 0.12 | 0.14 | 0.08 |
| Median age at first event (years) | 59.00 | 56.54 | 64.26 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 527
- Matched controls
- 5270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB09
ATC
hydrocortisone; systemic
567.0
323.0
442
47
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
+∞
323.0
527
*
H02AB06
ATC
prednisolone; systemic
13.5
127.7
463
1837
J45.9
ICD-10 Finland
Asthma, unspecified
10.6
120.0
288
538
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
9.3
109.2
287
602
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
212.6
102.4
103
6
J45.0
ICD-10 Finland
Predominantly allergic asthma
11.0
85.2
179
235
R03BB04
ATC
tiotropium bromide; inhalant
11.0
84.2
177
232
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.8
76.3
321
1117
R03DC03
ATC
montelukast; oral
7.0
75.7
226
508
R03AK06
ATC
salmeterol and fluticasone; inhalant
7.8
75.5
203
392
J45.1
ICD-10 Finland
Nonallergic asthma
11.3
72.4
147
175
J46
ICD-10 Finland
Status asthmaticus
30.6
71.3
96
38
R03AK08
ATC
formoterol and beclometasone; inhalant
16.0
67.7
114
89
R96
ICPC
Asthma
8.1
56.9
140
224
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
112.6
56.1
60
6
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.4
55.7
344
1577
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
9.3
55.1
123
167
R03DA04
ATC
theophylline; systemic, rectal
13.3
55.0
100
91
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.0
55.0
221
661
C03CA01
ATC
furosemide; systemic
4.8
54.9
238
770
R03BA05
ATC
fluticasone; inhalant
5.1
54.1
213
621
R03AC12
ATC
salmeterol; inhalant
11.6
50.9
99
103
R03AC02
ATC
salbutamol; inhalant
4.2
48.9
391
2150
R03BA08
ATC
ciclesonide; inhalant
7.3
48.8
128
221
J45.8
ICD-10 Finland
Mixed asthma
14.9
48.5
83
65
XG474
NOMESCO Finland
Exhalation nntrogen oxide
14.5
46.8
81
65
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
13.3
46.6
84
74
R03BA01
ATC
beclometasone; inhalant
5.3
45.5
160
399
J01MA14
ATC
moxifloxacin; systemic
6.8
45.2
125
231
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.9
44.7
253
1004
Z01.8
ICD-10 Finland
Other specified special examinations
4.1
43.8
218
768
L04AX01
ATC
azathioprine; systemic
9.1
43.3
96
126
R53
ICD-10 Finland
Malaise and fatigue
4.4
42.9
190
598
R03AC13
ATC
formoterol; inhalant
10.6
42.1
85
94
H02AB04
ATC
methylprednisolone; systemic
4.6
42.1
174
510
N03AX12
ATC
gabapentin; oral
4.7
41.6
165
463
J45
ICD-10 Finland
Asthma
5.7
40.1
127
276
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
5.7
39.9
127
277
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
7.7
39.3
97
150
WZC30
NOMESCO Finland
Teaching
4.9
39.2
147
386
R06.0
ICD-10 Finland
Dyspnoea
3.8
39.1
216
815
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
5.1
38.6
137
338
M05BA04
ATC
alendronic acid; oral
6.5
38.0
107
199
105
Kela drug reimbursment
Adrenal cortical hypofunction
65.0
36.7
42
7
UJF32
NOMESCO Finland
Coloscopy
3.5
35.3
215
861
R03BA02
ATC
budesonide; inhalant
4.0
35.3
170
561
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.8
35.3
185
655
H02AB07
ATC
prednisone; oral
4.4
35.2
147
425
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
4.0
34.7
165
537
J01MA12
ATC
levofloxacin; systemic
4.0
34.6
165
538
N02AA05
ATC
oxycodone; systemic
4.4
33.7
141
406
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
8.4
33.6
77
105
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.3
33.5
96
181
E23.03
ICD-10 Finland
Lack of ACTH
68.0
33.5
38
6
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.9
32.8
163
548
R50.9
ICD-10 Finland
Fever, unspecified
4.1
32.8
148
457
S18
ICPC
Laceration/cut
3.1
32.5
289
1495
A02BC05
ATC
esomeprazole; systemic
3.1
32.4
295
1550
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
9.0
32.3
71
90
R03AK07
ATC
formoterol and budesonide; inhalant
3.7
32.3
174
624
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.5
32.2
130
360
R01AD01
ATC
beclometasone; nasal
3.9
31.4
150
485
N02AX02
ATC
tramadol; systemic, rectal
2.9
30.2
297
1614
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.9
29.7
283
1502
R06AE07
ATC
cetirizine; oral
2.9
29.7
312
1762
TPH04
NOMESCO Finland
Cathetrisation of vein
3.4
29.5
173
656
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.8
29.5
108
269
E0000UV
ATC
NA
2.9
29.3
278
1469
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.9
29.1
259
1310
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
5.2
29.1
98
223
A07AA02
ATC
nystatin; oral
6.1
29.1
84
159
J01MA02
ATC
ciprofloxacin; systemic
2.9
29.0
265
1363
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.2
28.9
96
215
R03DC01
ATC
zafirlukast; oral
15.0
28.7
48
35
A02BC01
ATC
omeprazole; systemic
3.1
28.7
215
968
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
3.0
28.4
229
1081
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
41.5
28.4
35
9
C01CA24
ATC
epinephrine; parenteral
5.9
28.3
84
164
R11
ICD-10 Finland
Nausea and vomiting
5.5
28.2
89
187
N06AX21
ATC
duloxetine; oral
4.3
28.1
116
325
S97
ICPC
Chronic ulcer skin
7.8
28.0
67
97
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
5.8
27.9
84
167
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.8
27.5
100
246
R03BB01
ATC
ipratropium bromide; inhalant
10.0
27.5
56
62
N03AX16
ATC
pregabalin; oral
3.1
27.2
191
814
SPAT1263
SPAT
Sampling
2.7
26.2
288
1621
A01AB09
ATC
miconazole; local oral
4.5
26.1
100
259
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
25.6
26.0
36
15
UDH02
NOMESCO Finland
Rhinopharyngoscopy
5.6
26.0
80
163
SPAT1153
SPAT
Removal of sutures
2.8
25.9
228
1121
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.4
25.6
145
525
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.3
25.5
82
176
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.7
25.2
123
397
C07AB07
ATC
bisoprolol; oral
2.6
24.9
289
1662
A02BC02
ATC
pantoprazole; systemic
2.8
24.7
399
2769
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
25.9
24.7
34
14
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.8
24.4
88
213
J01FF01
ATC
clindamycin; systemic
2.9
24.4
197
911
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.6
24.3
124
414
A02BA02
ATC
ranitidine; systemic
3.1
24.3
161
653
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
32.8
24.0
31
10
SPAT1310
SPAT
Counselling related to known health issue
2.7
23.9
218
1080
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
7.4
23.8
58
86
SPAT1254
SPAT
Administration of medicine
3.5
23.7
124
421
R01AD08
ATC
fluticasone; nasal
2.7
23.7
214
1055
J47
ICD-10 Finland
Bronchiectasis
16.3
23.7
38
25
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.6
23.6
119
392
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
6.0
23.3
67
125
E000002
ATC
NA
4.1
23.0
98
279
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.8
22.8
81
193
318
Kela drug reimbursment
Teriparatide
34.0
22.6
29
9
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
9.0
22.4
48
58
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.2
22.4
92
253
N05BA04
ATC
oxazepam; oral
2.8
22.2
183
846
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.9
22.1
98
289
A02BC03
ATC
lansoprazole; oral
2.6
22.0
214
1089
G47.3
ICD-10 Finland
Sleep apnoea
2.9
22.0
158
670
H02AA02
ATC
fludrocortisone; oral
23.4
21.9
31
14
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.7
21.9
104
325
R03AC03
ATC
terbutaline; inhalant
3.4
21.8
120
422
R03AK11
ATC
formoterol and fluticasone; inhalant
10.3
21.7
43
45
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
10.3
21.7
43
45
SPAT1262
SPAT
Handing over of treatment supplies
3.0
21.7
145
584
H05AA02
ATC
teriparatide; parenteral
32.7
21.7
28
9
NH3EA
NOMESCO Finland
Feet X-ray examination with load
13.1
21.7
38
31
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
21.5
295
1800
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.1
21.5
91
257
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.8
21.4
100
308
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.4
21.2
323
2078
N06AX16
ATC
venlafaxine; oral
3.3
21.1
121
438
ZX120
NOMESCO Finland
Intravenous
4.0
21.0
92
267
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.1
21.0
138
548
N06AA09
ATC
amitriptyline; systemic
3.8
21.0
98
301
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
10.0
21.0
42
45
SPAT1260
SPAT
Consultation of another employee
3.0
20.9
140
561
R02
ICPC
Shortness of breath/dyspnoea
3.5
20.9
106
349
R06AX26
ATC
fexofenadine; oral
4.5
20.8
77
191
J01FA06
ATC
roxithromycin; oral
2.4
20.6
269
1589
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
5.2
20.5
66
141
A06AC01
ATC
ispaghula (psylla seeds); oral
2.7
20.4
176
828
J01FA09
ATC
clarithromycin; systemic
2.5
20.4
221
1181
R06AE09
ATC
levocetirizine; oral
3.1
20.4
127
483
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
20.3
246
1393
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.4
20.3
285
1743
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
8.4
20.2
45
58
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
20.2
121
450
SPAT1325
SPAT
Vaccination
2.5
20.2
225
1219
L04AA06
ATC
mycophenolic acid; systemic
12.4
20.1
36
31
M81.4
ICD-10 Finland
Drug-induced osteoporosis
60.0
20.1
23
*
A07EC01
ATC
sulfasalazine; oral, rectal
4.1
20.0
83
229
J02AC01
ATC
fluconazole; systemic
2.4
20.0
278
1685
ZXD05
NOMESCO Finland
Urgent procedure
2.5
19.9
210
1103
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.4
19.9
261
1537
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.7
19.8
168
778
E27.2
ICD-10 Finland
Addisonian crisis
207.4
19.7
20
*
XX3DW
NOMESCO Finland
Time consuming IT work
3.8
19.6
89
266
R5140
NOMESCO Finland
Monitoring the use of the aid
3.8
19.5
90
273
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.0
19.5
127
500
L28
ICPC
Limited function/disability (L)
3.2
19.4
116
430
Z71.8
ICD-10 Finland
Other specified counselling
2.6
19.3
172
819
M79.0
ICD-10 Finland
Rheumatism, unspecified
6.1
19.3
54
97
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
6.1
19.3
54
97
R07.4
ICD-10 Finland
Chest pain, unspecified
2.6
19.3
186
926
R01AD12
ATC
fluticasone furoate; nasal
2.5
19.3
211
1125
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
8.3
19.2
43
56
JN3AD
NOMESCO Finland
Abdominal CT examination
4.2
19.2
77
206
J01FA10
ATC
azithromycin; systemic
2.4
19.1
353
2436
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.2
19.0
75
198
J01DB01
ATC
cefalexin; oral
3.0
18.9
460
3676
SPAT1301
SPAT
No procedures
2.4
18.9
211
1136
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.3
18.8
255
1510
R01AD09
ATC
mometasone; nasal
2.3
18.7
286
1794
H03AA01
ATC
levothyroxine sodium; systemic
2.6
18.7
175
856
TDM10
NOMESCO Finland
Puncture of maxillary antrum
6.2
18.7
51
89
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.4
18.6
222
1231
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.8
18.4
83
246
S01GX01
ATC
cromoglicic acid; ophthalmic
2.7
18.3
146
648
N02BE01
ATC
paracetamol; systemic, rectal
3.4
18.3
481
3980
E000001
ATC
NA
2.7
18.3
149
671
SPAT1249
SPAT
Treatment-related counselling outside office
2.3
18.3
246
1445
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.6
18.2
43
61
AA1AD
NOMESCO Finland
CT of head and brain
2.6
18.1
159
747
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.4
18.1
210
1146
XQ800
NOMESCO Finland
Prick test
4.0
18.1
77
217
R51.80
ICD-10 Finland
Headache
2.9
18.0
123
497
L04AA13
ATC
leflunomide; oral
8.2
17.9
40
52
J01AA02
ATC
doxycycline; systemic
2.7
17.9
443
3490
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
5.0
17.6
58
127
A06AD11
ATC
lactulose; oral
3.1
17.5
105
386
D07AC01
ATC
betamethasone; topical
2.3
17.4
220
1243
E000003
ATC
NA
5.4
17.4
53
106
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
6.1
17.4
48
85
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
5.2
17.4
55
115
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.1
17.3
104
383
A46
ICD-10 Finland
Erysipelas
3.1
17.2
104
385
X59
ICD-10 Finland
Exposure to unspecified factor
2.8
17.2
132
570
A03FA01
ATC
metoclopramide; systemic, rectal
2.6
17.1
153
724
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
26.6
17.0
23
9
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
5.3
17.0
53
109
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.3
16.8
93
323
N05AH04
ATC
quetiapine; oral
2.8
16.8
121
501
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.0
16.7
70
195
M25.5
ICD-10 Finland
Pain in joint
2.3
16.5
192
1037
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
6.1
16.4
45
79
SPAT1255
SPAT
Intravenous administration of medicine
4.0
16.4
68
187
N03AE01
ATC
clonazepam; systemic
4.5
16.4
59
142
M81.9
ICD-10 Finland
Osteoporosis, unspecified
6.4
16.3
43
72
P01BA02
ATC
hydroxychloroquine; oral
3.5
16.3
82
266
R60.0
ICD-10 Finland
Localized oedema
3.3
16.2
88
300
C03DA01
ATC
spironolactone; oral
3.6
16.1
77
239
XG410
NOMESCO Finland
Flow-volume spirometry
6.0
16.1
45
81
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.2
16.1
93
332
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.4
16.0
175
915
M79.6
ICD-10 Finland
Pain in limb
2.2
16.0
228
1351
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
6.1
15.9
44
78
ZXA10
NOMESCO Finland
Bilateral
2.7
15.9
128
567
P01AB01
ATC
metronidazole; oral, rectal
2.2
15.9
247
1520
N06AX11
ATC
mirtazapine; oral
2.2
15.8
204
1155
R03BC03
ATC
nedocromil; inhalant
3.9
15.7
68
194
R01AD05
ATC
budesonide; nasal
3.8
15.7
70
205
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.5
15.7
77
244
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
5.2
15.7
49
101
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.0
15.7
66
184
M05BX04
ATC
denosumab; parenteral
4.7
15.7
54
124
TQW80
NOMESCO Finland
Local dermatologic skincare
6.7
15.7
40
64
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.9
15.6
68
195
TAB00
NOMESCO Finland
Lumbar puncture
4.9
15.6
52
115
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
7.4
15.6
37
53
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
5.1
15.6
50
106
E27.9
ICD-10 Finland
Disorder of adrenal gland, unspecified
164.7
15.6
16
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
39.3
15.5
19
5
R01BA52
ATC
pseudoephedrine, combinations; oral
2.2
15.4
208
1196
L04AD01
ATC
ciclosporin; systemic
9.1
15.4
32
37
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
6.5
15.3
40
66
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.3
15.3
181
978
SPAT1312
SPAT
General health counselling
2.2
15.3
204
1167
49300
ICD-8 Finland
Asthma, bronchiale
7.7
15.2
35
48
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.3
15.2
81
274
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.9
15.1
98
379
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
9.9
15.1
30
32
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.6
15.1
71
218
G43.9
ICD-10 Finland
Migraine, unspecified
4.3
15.1
57
144
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.4
15.0
156
790
A07EC02
ATC
mesalazine; oral, rectal
4.4
15.0
56
140
TGC00
NOMESCO Finland
Bronchial lavation
7.8
14.9
34
46
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.8
14.8
42
77
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.1
14.8
47
99
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.3
14.7
165
867
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.0
14.7
60
163
M48.0
ICD-10 Finland
Spinal stenosis
3.0
14.3
88
327
N05BA01
ATC
diazepam; systemic, rectal
2.8
14.2
100
407
D07AA02
ATC
hydrocortisone; topical
2.8
14.2
103
427
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
43.8
14.2
17
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.3
14.2
76
258
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
11.3
14.1
26
24
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
5.7
13.9
40
75
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
13.9
174
959
A07EA06
ATC
budesonide; oral, local oral
5.5
13.8
41
80
M54.5
ICD-10 Finland
Low back pain
2.1
13.8
211
1268
B01AB05
ATC
enoxaparin; parenteral
2.2
13.7
186
1058
EBA10
NOMESCO Finland
Surgical removal of tooth
3.0
13.5
82
303
A01AB04
ATC
amphotericin B; local oral
5.1
13.5
43
91
R06AX13
ATC
loratadine; oral
2.6
13.5
112
502
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
11.9
13.4
24
21
R81
ICPC
Pneumonia
6.4
13.4
35
58
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.5
13.3
39
75
J31.0
ICD-10 Finland
Chronic rhinitis
3.6
13.3
62
189
M54.4
ICD-10 Finland
Lumbago with sciatica
2.5
13.3
122
575
B01AA03
ATC
warfarin; systemic
2.6
13.2
108
478
ZXE00
NOMESCO Finland
One hour or less
2.0
13.1
237
1513
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.9
13.0
54
149
L17
ICPC
Foot/toe symptom/complaint
2.2
13.0
153
816
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
5.7
13.0
37
69
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.2
12.9
71
242
L04AB01
ATC
etanercept; parenteral
8.8
12.9
27
32
I50.9
ICD-10 Finland
Heart failure, unspecified
3.1
12.9
73
257
M79.7
ICD-10 Finland
Fibromyalgia
5.0
12.9
41
87
H04.10
ICD-10 Finland
Dry eye syndrome
3.0
12.8
77
282
ZYC01
NOMESCO Finland
Remote contact by phone
4.3
12.7
47
116
J01CA04
ATC
amoxicillin; systemic
2.3
12.7
441
3636
J01FA15
ATC
telithromycin; oral
2.8
12.7
87
345
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.8
12.7
55
157
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
6.3
12.6
33
55
H26.3
ICD-10 Finland
Drug-induced cataract
17.9
12.6
19
11
N02AC04
ATC
dextropropoxyphene; oral
5.3
12.6
38
76
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.2
12.6
69
235
R52.2
ICD-10 Finland
Other chronic pain
5.0
12.5
40
85
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
25.0
12.5
17
7
101
Kela drug reimbursment
Anterior pituitary hypofunction
25.0
12.5
17
7
K50.1
ICD-10 Finland
Crohn disease of large intestine
13.6
12.5
21
16
J98.0
ICD-10 Finland
Diseases of bronchus, not elsewhere classified
133.0
12.5
13
*
N05CF01
ATC
zopiclone; oral
2.1
12.5
192
1145
L04AA01
ATC
[U] ciclosporin; systemic
8.8
12.4
26
31
NF1AA
NOMESCO Finland
Hip X-ray examination
3.3
12.4
64
211
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
4.5
12.4
44
105
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.7
12.3
31
49
A07EA02
ATC
hydrocortisone; rectal
6.4
12.3
32
53
WX892
NOMESCO Finland
Monitored bed care
3.5
12.1
58
180
D07AB02
ATC
hydrocortisone butyrate; topical
2.1
12.1
171
982
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
5.2
12.1
37
75
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.3
12.1
124
616
ZX112
NOMESCO Finland
Subcutaneous
7.1
12.1
29
43
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.5
12.1
58
181
SPAT1216
SPAT
Assessment of functional ability
2.6
12.0
92
391
J32.4
ICD-10 Finland
Chronic pansinusitis
8.2
12.0
26
33
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.2
12.0
37
76
A41.9
ICD-10 Finland
Sepsis, unspecified
4.9
12.0
39
85
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
11.9
168
963
L88
ICPC
Rheumatoid/seropositive arthritis
5.0
11.9
38
81
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.9
11.9
29
44
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
15.1
11.9
19
13
M70.6
ICD-10 Finland
Trochanteric bursitis
2.6
11.9
91
385
A07AA09
ATC
vancomycin; oral
10.0
11.8
23
24
Z00.0
ICD-10 Finland
General medical examination
2.3
11.8
122
608
SPAT1229
SPAT
Assessment of need for aid
3.3
11.7
61
202
A04AA01
ATC
ondansetron; systemic, rectal
3.4
11.7
58
185
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.2
11.7
65
224
D72.1
ICD-10 Finland
Eosinophilia
30.8
11.7
15
5
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.4
11.7
115
559
SAA04
NOMESCO Finland
Special inverstigation of mouth
3.6
11.7
53
158
R06AX27
ATC
desloratadine; oral
2.1
11.6
172
1004
J30.3
ICD-10 Finland
Other allergic rhinitis
4.7
11.6
39
88
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
7.0
11.6
28
42
N03AX09
ATC
lamotrigine; oral
4.0
11.5
46
123
A28
ICPC
Limited function/disability NOS
2.6
11.5
89
380
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.0
11.4
176
1043
D07AB08
ATC
desonide; topical
2.8
11.4
78
310
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
11.4
94
415
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.5
11.4
33
63
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.5
11.4
99
450
R4180
NOMESCO Finland
Podiatric therapy
9.9
11.3
22
23
A01
ICPC
Pain general/multiple sites
3.3
11.3
58
190
K07.60
ICD-10 Finland
Snapping jaw
3.9
11.3
47
130
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
35.9
11.3
14
*
E000006
ATC
NA
3.4
11.3
56
179
UDC00
NOMESCO Finland
Ear microscopy
3.4
11.3
56
179
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
11.3
88
377
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.0
11.3
66
238
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
17.5
11.3
17
10
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.4
11.2
56
180
D02AE01
ATC
carbamide; topical
3.4
11.2
54
169
R01AD11
ATC
triamcinolone; nasal
3.0
11.2
68
251
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
3.3
11.1
57
187
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.1
11.1
62
215
L04AB04
ATC
adalimumab; parenteral
6.2
11.0
29
49
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.6
11.0
49
144
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.6
11.0
49
144
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
4.3
11.0
40
98
R60.9
ICD-10 Finland
Oedema, unspecified
4.3
11.0
40
98
UDM02
NOMESCO Finland
Sinoscopy
6.7
10.9
27
42
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.7
10.9
78
319
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.3
10.9
112
554
L86
ICPC
Back syndrome with radiating pain
3.7
10.9
48
140
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
9.1
10.9
22
25
M13.9
ICD-10 Finland
Arthritis, unspecified
3.2
10.9
60
205
X58
ICD-10 Finland
Exposure to other specified factors
2.6
10.8
85
365
E66.8
ICD-10 Finland
Other obesity
3.6
10.8
48
141
D07AD01
ATC
clobetasol; topical
2.3
10.8
105
506
R60.1
ICD-10 Finland
Generalized oedema
18.3
10.8
16
9
E23.00
ICD-10 Finland
Panhypopituitarism
28.7
10.8
14
5
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.5
10.7
90
402
RD211
NOMESCO Finland
NA
3.9
10.7
43
116
R01AC01
ATC
cromoglicic acid; nasal
4.2
10.7
40
101
GD1AD
NOMESCO Finland
Thorax CT examination
4.6
10.6
36
82
R52.9
ICD-10 Finland
Pain, unspecified
3.0
10.6
62
223
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.2
10.6
115
584
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
5.4
10.6
31
60
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
6.1
10.6
28
48
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.3
10.6
54
177
Z01.9
ICD-10 Finland
Special examination, unspecified
3.8
10.5
44
123
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.4
10.4
96
449
K51.8
ICD-10 Finland
Other ulcerative colitis
8.5
10.4
22
27
R06AX22
ATC
ebastine; oral
2.2
10.4
117
602
ZX114
NOMESCO Finland
Intramuscular
7.3
10.4
24
34
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.6
10.4
78
328
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
33.2
10.4
13
*
N30.0
ICD-10 Finland
Acute cystitis
2.4
10.4
93
429
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
10.9
10.3
19
18
A03FA02
ATC
cisapride; oral, rectal
3.1
10.3
58
202
SPAT1097
SPAT
Recording of ECG
2.4
10.3
93
431
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.9
10.3
33
71
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
7.7
10.3
23
31
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
10.3
73
295
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
10.2
294
2154
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
4.1
10.2
39
100
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
10.2
211
1378
ZY010
NOMESCO Finland
Hospital outpatient
3.7
10.2
44
126
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
8.1
10.2
22
28
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.6
10.2
46
137
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.8
10.2
42
116
K51.5
ICD-10 Finland
Left sided colitis
5.3
10.2
30
59
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.8
10.2
69
271
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
6.7
10.1
25
39
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
2.1
10.1
137
761
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
8.7
10.1
21
25
L95
ICPC
Osteoporosis
5.1
10.1
31
64
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.5
10.1
47
144
R55
ICD-10 Finland
Syncope and collapse
2.8
10.0
68
268
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
5.9
9.9
27
48
WX723
NOMESCO Finland
CPAP therapy
4.7
9.9
33
74
PAW37
NOMESCO Finland
Biopsy of temporal artery
17.1
9.9
15
9
WX213
NOMESCO Finland
Lower leg blockade
12.5
9.9
17
14
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.4
9.9
88
405
N04BC05
ATC
pramipexole; oral
3.3
9.9
50
163
SPAT1131
SPAT
Colonoscopy
4.8
9.9
32
70
WX402
NOMESCO Finland
General anaesthesia
2.2
9.9
108
550
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
6.7
9.8
24
37
R09
ICPC
Sinus symptom/complaint
3.0
9.8
56
198
R03BC01
ATC
cromoglicic acid; inhalant
7.6
9.8
22
30
SPAT1211
SPAT
Application of soft bandage
2.8
9.7
65
255
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.0
9.7
56
200
M35.3
ICD-10 Finland
Polymyalgia rheumatica
4.6
9.7
33
76
3028
Kela drug reimbursment
Mepolizumab
56.0
9.7
11
*
L30.3
ICD-10 Finland
Infective dermatitis
4.9
9.7
31
67
ZZA00
NOMESCO Finland
Split skin graft
5.6
9.6
27
50
M47.82
ICD-10 Finland
Other spondylosis, cervical region
4.1
9.6
37
96
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
3.5
9.6
44
133
E87.6
ICD-10 Finland
Hypokalaemia
4.8
9.6
31
68
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.3
9.5
48
156
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.9
9.5
38
102
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.3
9.5
28
55
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.7
9.5
41
118
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
101.8
9.4
10
*
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
30.6
9.4
12
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.4
9.4
85
393
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
7.1
9.4
22
32
E27.8
ICD-10 Finland
Other specified disorders of adrenal gland
+∞
9.4
9
*
D84.18
ICD-10 Finland
Other specified defect in the complement system
+∞
9.4
9
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.4
9.4
45
141
E66.01
ICD-10 Finland
Obesity due to excess calories
2.8
9.4
61
233
-44
ICPC
Preventive immunization/medic
2.9
9.3
58
217
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
10.9
9.3
17
16
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.4
9.3
44
136
K29.7
ICD-10 Finland
Gastritis, unspecified
4.6
9.3
31
70
D07AC13
ATC
mometasone; topical
1.9
9.3
168
1043
K50.9
ICD-10 Finland
Crohn disease, unspecified
7.5
9.3
21
29
A44
ICPC
General and Unspecified, Preventive immunization/medic
3.0
9.3
54
194
M05BA07
ATC
risedronic acid; oral
4.9
9.2
29
62
N06AB04
ATC
citalopram; systemic
2.0
9.2
132
750
L01
ICPC
Neck symptom/complaint
2.3
9.2
86
406
R1250
NOMESCO Finland
Evaluation of functional capability
5.8
9.2
25
45
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
3.2
9.1
48
161
J01EA01
ATC
trimethoprim; systemic
1.9
9.1
150
899
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.4
9.1
83
385
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.6
9.1
70
297
R42
ICD-10 Finland
Dizziness and giddiness
2.1
9.1
118
645
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
10.3
9.1
17
17
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
15.9
9.1
14
9
C10AC01
ATC
colestyramine; oral
5.2
9.1
27
54
C08DA01
ATC
verapamil; systemic
3.7
9.0
38
107
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
37.4
9.0
11
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.1
9.0
119
654
C09CA01
ATC
losartan; oral
2.0
9.0
129
731
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.6
9.0
39
113
J01
ICD-10 Finland
Acute sinusitis
3.6
9.0
39
113
Z3231
NOMESCO Finland
Registered nurse
1.9
9.0
162
1001
L03
ICPC
Low back symptom/complaint
2.0
8.9
142
838
K50.8
ICD-10 Finland
Other Crohn disease
8.2
8.9
19
24
M05BA06
ATC
ibandronic acid; systemic
7.0
8.9
21
31
N05BA06
ATC
lorazepam; systemic, sublingual
3.7
8.9
38
109
N03AG01
ATC
valproic acid; systemic, rectal
3.1
8.9
47
159
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
4.9
8.9
28
60
C01DA14
ATC
isosorbide mononitrate; oral
2.5
8.9
69
296
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.4
8.8
31
74
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.2
8.8
46
154
K59.0
ICD-10 Finland
Constipation
3.4
8.8
41
126
F43.29
ICD-10 Finland
Adaptation disorder UNS
6.8
8.7
21
32
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
4.3
8.7
31
75
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
7.8
8.7
19
25
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
8.7
65
272
A07DA03
ATC
loperamide; oral
4.1
8.7
33
85
297
Kela drug reimbursment
NA
50.8
8.7
10
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.5
8.7
71
313
R05
ICD-10 Finland
Cough
2.0
8.7
115
633
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
3.7
8.7
37
106
WX110
NOMESCO Finland
Local anesthesy
1.8
8.6
365
2947
WX725
NOMESCO Finland
Noninvasive ventilation
3.6
8.6
38
112
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.6
8.6
37
107
UJF92
NOMESCO Finland
Capsular endoscopy
5.5
8.5
24
45
RS222
NOMESCO Finland
NA
7.5
8.5
19
26
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.9
8.5
34
92
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
20.4
8.5
12
6
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
20.4
8.5
12
6
J01DA01
ATC
[U] cefalexin; systemic
1.7
8.5
330
2585
M01AH01
ATC
celecoxib; oral (coxibs)
2.0
8.5
112
615
R05
ICPC
Cough
2.0
8.5
132
769
H25.1
ICD-10 Finland
Senile nuclear cataract
2.0
8.5
115
637
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
8.4
132
775
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.4
8.4
24
46
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.4
8.4
74
339
N06AX12
ATC
bupropion; oral
3.1
8.4
45
154
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
8.7
8.4
17
20
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.2
8.4
42
137
SPAT1252
SPAT
Overall medication plan or its review
2.9
8.3
49
178
L16
ICPC
Ankle symptom/complaint
2.5
8.3
65
278
R4190
NOMESCO Finland
Nutritional therapy
4.0
8.3
32
84
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
4.7
8.3
27
60
T78.4
ICD-10 Finland
Allergy, unspecified
3.6
8.3
36
105
N05CD07
ATC
temazepam; oral
2.4
8.2
70
314
B03BA03
ATC
hydroxocobalamin; parenteral
3.4
8.2
39
122
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.1
8.2
31
80
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.8
8.2
53
205
XF600
NOMESCO Finland
Bloodpressure measurement
3.1
8.2
44
151
WW200
NOMESCO Finland
Immunization
4.4
8.1
28
66
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.9
8.1
48
175
R49.08
ICD-10 Finland
Other specified dysphonia
5.2
8.1
24
48
G72.9
ICD-10 Finland
Myopathy, unspecified
11.9
8.1
14
12
120
Kela drug reimbursment
Hypogammaglobulinaemia
33.9
8.1
10
*
HAHOM
NOMESCO Finland
NA
10.3
8.1
15
15
N06AX26
ATC
vortioxetine; oral
3.1
8.0
42
141
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
22.4
8.0
11
5
M54.6
ICD-10 Finland
Pain in thoracic spine
2.9
8.0
47
171
-1
NOMESCO Finland
NA
1.8
7.9
185
1237
WX002
NOMESCO Finland
Sedation and analgesia
2.0
7.9
113
637
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
6.3
7.9
20
33
XQ820
NOMESCO Finland
Exposure to medicinal substance
13.3
7.9
13
10
TQW11
NOMESCO Finland
Vacuum treatment of wound
5.9
7.9
21
37
R06.2
ICD-10 Finland
Wheezing
3.8
7.9
32
88
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
8.6
7.9
16
19
C08CA01
ATC
amlodipine; oral
1.8
7.9
180
1193
XKC03
NOMESCO Finland
Water cystometry
4.6
7.9
26
59
S22.3
ICD-10 Finland
Fracture of rib
3.2
7.9
40
132
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.4
7.8
70
321
L29
ICPC
Musculoskeletal sympt/complt other
2.7
7.8
51
198
J05AH02
ATC
oseltamivir; oral
11.0
7.8
14
13
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
11.0
7.8
14
13
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
7.1
7.8
18
26
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
7.1
7.8
18
26
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.7
7.8
33
94
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.4
7.8
27
64
A02BA04
ATC
nizatidine; systemic
2.7
7.8
53
210
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
6.5
7.8
19
30
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.5
7.8
60
257
J37.0
ICD-10 Finland
Chronic laryngitis
4.5
7.7
26
60
134
Kela drug reimbursment
General erythroderma
45.7
7.7
9
*
R03DX09
ATC
mepolizumab; parenteral
45.7
7.7
9
*
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
45.7
7.7
9
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
4.9
7.7
24
51
WZA10
NOMESCO Finland
Long statement of health and health related matters
7.6
7.7
17
23
S19
ICPC
Skin injury other
4.2
7.7
28
70
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
6.9
7.6
18
27
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
5.3
7.6
22
43
RS142
NOMESCO Finland
NA
18.7
7.6
11
6
M05BA01
ATC
etidronic acid; systemic
18.7
7.6
11
6
R03BB07
ATC
umeclidinium bromide; inhalant
12.1
7.6
13
11
A10BJ06
ATC
semaglutide; parenteral
4.3
7.6
27
66
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.2
7.6
80
397
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
25.4
7.6
10
*
L99
ICPC
Musculoskeletal disease other
5.9
7.6
20
35
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
5.9
7.6
20
35
WX720
NOMESCO Finland
Own respiration
4.1
7.6
28
71
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.2
7.6
39
130
D01AE16
ATC
amorolfine; topical
2.4
7.6
64
287
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
10.2
7.6
14
14
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
5.0
7.5
23
48
XQ802
NOMESCO Finland
Epicutan test
3.4
7.5
35
108
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
3.4
7.5
35
108
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.0
7.5
43
153
SPAT1059
SPAT
Spirometry at the office
3.3
7.5
36
114
D02AX
ATC
Other emollients and protectives
3.8
7.5
30
82
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.4
7.5
65
293
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
6.6
7.5
18
28
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
6.6
7.5
18
28
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
6.6
7.5
18
28
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.5
7.5
33
98
JN4AD
NOMESCO Finland
Body CT examination
2.8
7.5
48
185
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.6
7.4
32
93
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
13.6
7.4
12
9
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
13.6
7.4
12
9
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
4.9
7.4
23
49
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.7
7.4
31
88
C07AB02
ATC
metoprolol; systemic
1.9
7.4
109
622
R49.01
ICD-10 Finland
Functional dysphonia
4.0
7.4
28
73
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
3.3
7.4
35
110
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.0
7.4
42
149
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.9
7.4
127
767
R07.3
ICD-10 Finland
Other chest pain
2.5
7.4
57
244
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.7
7.3
50
198
XX1VW
NOMESCO Finland
Written report from radiologist
11.1
7.3
13
12
3027
Kela drug reimbursment
Benralizumab
+∞
7.3
7
*
RF420
NOMESCO Finland
NA
6.4
7.3
18
29
M01CB01
ATC
sodium aurothiomalate; parenteral
5.6
7.3
20
37
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
3.2
7.3
36
117
SBB10
NOMESCO Finland
Teeth copy
2.7
7.3
47
182
R52.0
ICD-10 Finland
Acute pain
4.3
7.2
25
60
H26.02
ICD-10 Finland
Presenil cataract
5.2
7.2
21
42
B35.3
ICD-10 Finland
Tinea pedis
3.9
7.2
28
75
S29
ICPC
Skin symptom/complaint other
2.0
7.2
91
488
J01XX08
ATC
linezolid; systemic
30.5
7.2
9
*
B01AF02
ATC
apixaban; oral
2.7
7.2
49
195
D01AE15
ATC
terbinafine; topical
2.9
7.2
42
153
Z02.7
ICD-10 Finland
Issue of medical certificate
2.9
7.2
42
153
UKC02
NOMESCO Finland
Cystoscopy
2.1
7.2
85
443
G44.2
ICD-10 Finland
Tension-type headache
2.1
7.1
81
414
XA800
NOMESCO Finland
Neuropsychological investigation
3.2
7.1
35
113
M03BX01
ATC
baclofen; systemic
5.8
7.1
19
34
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
2.3
7.1
63
288
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.2
7.1
73
360
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
9.0
7.1
14
16
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
7.1
213
1523
L60.0
ICD-10 Finland
Ingrowing nail
3.5
7.0
31
92
K50.0
ICD-10 Finland
Crohn disease of small intestine
7.1
7.0
16
23
M35.7
ICD-10 Finland
Hypermobility syndrome
7.1
7.0
16
23
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
7.0
88
469
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.7
7.0
45
173
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.7
7.0
29
82
WX780
NOMESCO Finland
Remote monitoring CPAP
3.7
7.0
29
82
RF410
NOMESCO Finland
NA
6.5
7.0
17
27
SPAT1240
SPAT
Therapeutic discussion
2.3
7.0
62
283
I50.0
ICD-10 Finland
Congestive heart failure
3.2
7.0
35
115
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.8
7.0
42
156
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
3.9
7.0
27
72
A02BX02
ATC
sucralfate; oral
3.5
7.0
31
93
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
7.7
6.9
15
20
M45
ICD-10 Finland
Ankylosing spondylitis
4.5
6.9
23
53
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.8
6.9
143
916
S92.3
ICD-10 Finland
Fracture of metatarsal bone
3.8
6.9
27
73
A04
ICPC
Weakness/tiredness general
2.2
6.9
71
350
J96.0
ICD-10 Finland
Acute respiratory failure
6.8
6.9
16
24
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.3
6.8
64
301
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.0
6.8
96
535
M79.1
ICD-10 Finland
Myalgia
2.1
6.8
77
393
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
9.5
6.8
13
14
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
6.8
124
761
M01AH02
ATC
rofecoxib; oral
2.1
6.8
75
381
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.8
6.8
142
911
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.5
6.8
50
208
M47.9
ICD-10 Finland
Spondylosis, unspecified
3.8
6.8
27
74
Q32.21
ICD-10 Finland
Secondary congenital bronchomalacia
40.6
6.8
8
*
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
17.0
6.8
10
6
N05CF02
ATC
zolpidem; oral
1.9
6.7
104
601
E27.0
ICD-10 Finland
Other adrenocortical overactivity
22.8
6.7
9
*
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
3.1
6.7
35
119
K08.3
ICD-10 Finland
Retained dental root
2.7
6.7
43
166
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.0
6.7
25
65
L29.9
ICD-10 Finland
Pruritus, unspecified
4.7
6.7
21
46
I95.9
ICD-10 Finland
Hypotension, unspecified
8.0
6.6
14
18
J01CA08
ATC
pivmecillinam; oral
1.6
6.6
215
1561
HMAK
NOMESCO Finland
NA
2.1
6.6
72
364
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.9
6.6
38
136
49302
ICD-8 Finland
Asthma, Rhinitis allergica cum asthmate bronchiali
12.4
6.6
11
9
R52.1
ICD-10 Finland
Chronic intractable pain
12.4
6.6
11
9
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.9
6.6
20
42
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
3.7
6.6
27
76
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
8.9
6.6
13
15
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
7.0
6.6
15
22
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.1
6.5
34
115
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.9
6.5
94
531
R04.0
ICD-10 Finland
Epistaxis
2.7
6.5
42
162
R01AC02
ATC
levocabastine; nasal
4.0
6.5
24
62
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.2
6.4
62
297
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
70.7
6.4
7
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.2
6.4
32
105
NDG71
NOMESCO Finland
Arthrodes of first MP joint
14.5
6.4
10
7
N29
ICPC
Neurological sympt/complt other
5.0
6.4
19
39
B80
ICPC
Iron deficiency anaemia
5.0
6.4
19
39
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.6
6.4
274
2131
Z2445
NOMESCO Finland
Psychologist
3.0
6.4
34
117
N03AX11
ATC
topiramate; oral
4.3
6.4
22
53
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.7
6.4
26
73
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.1
6.4
23
58
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
8.3
6.4
13
16
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
8.3
6.4
13
16
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
8.3
6.4
13
16
127
Kela drug reimbursment
Transplant complication
6.1
6.3
16
27
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
3.1
6.3
33
112
TKC22
NOMESCO Finland
Catheterisation instruction
4.9
6.3
19
40
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
18.3
6.3
9
5
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
18.3
6.3
9
5
ABD32
NOMESCO Finland
Implantation of temporary spinal stimulation device
18.3
6.3
9
5
N19
ICD-10 Finland
Unspecified kidney failure
4.2
6.3
22
54
R03DX10
ATC
benralizumab; systemic
+∞
6.3
6
*
251
Kela drug reimbursment
NA
+∞
6.3
6
*
E24.2
ICD-10 Finland
Drug-induced Cushing syndrome
+∞
6.3
6
*
AEA24
NOMESCO Finland
Removal of spinal stimulation elecrode
+∞
6.3
6
*
L01XX23
ATC
mitotane; oral
+∞
6.3
6
*
R03DB04
ATC
theophylline and adrenergics; systemic
+∞
6.3
6
*
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
+∞
6.3
6
*
A12AA04
ATC
calcium carbonate; oral
7.2
6.3
14
20
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
27.0
6.2
8
*
ZYY98
NOMESCO Finland
Missed treatment contact, no notification given by patient
27.0
6.2
8
*
RS130
NOMESCO Finland
NA
27.0
6.2
8
*
H02.4
ICD-10 Finland
Ptosis of eyelid
4.6
6.2
20
45
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
4.6
6.2
20
45
H11.3
ICD-10 Finland
Conjunctival haemorrhage
3.3
6.2
29
91
103
Kela drug reimbursment
Diabetes, insulin-treated
1.8
6.2
128
816
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
6.2
52
232
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.8
6.2
37
138
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.0
6.2
23
60
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
4.0
6.2
23
60
WX290
NOMESCO Finland
Other blockade of nerve
1.6
6.2
221
1638
S01
ICPC
Pain/tenderness of skin
3.1
6.2
31
103
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
7.8
6.2
13
17
C09CA06
ATC
candesartan; oral
1.8
6.1
120
751
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.3
6.1
29
92
M05BB03
ATC
alendronic acid and colecalciferol; oral
4.5
6.1
20
46
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
6.1
127
808
C08CA13
ATC
lercanidipine; oral
2.1
6.1
68
347
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
8.7
6.1
12
14
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
8.7
6.1
12
14
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.8
6.1
24
66
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
5.3
6.1
17
33
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
5.3
6.1
17
33
WX204
NOMESCO Finland
Axillary plexus blockaced
3.9
6.1
23
61
N06AB05
ATC
paroxetine; oral
2.5
6.0
46
196
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.4
6.0
35
724
D50.8
ICD-10 Finland
Other iron deficiency anaemias
6.1
6.0
15
25
ZX100
NOMESCO Finland
Oral
6.1
6.0
15
25
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
5.7
6.0
16
29
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
2.9
6.0
35
127
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.6
6.0
43
177
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.6
6.0
280
2211
JN4BD
NOMESCO Finland
Extensive body CT
2.1
6.0
65
326
OAB43
SPAT
NA
0.4
6.0
22
543
Mortality – FinRegistry
↥Association
Association between endpoint DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY | 3.3 [2.56, 4.25] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.61 |
During the follow-up period (1.1.1998 — 31.12.2019), 228 out of 1280 females with DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY | 3.434 [2.34, 5.04] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.017 |
During the follow-up period (1.1.1998 — 31.12.2019), 146 out of 676 males with DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY died.
Mortality risk
Mortality risk for people of age
years, who have DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.391% | 0.637% |
| 5 | 2.02% | 4.028% |
| 10 | 5.264% | 9.927% |
| 15 | 9.781% | 17.921% |
| 20 | 17.281% | 28.456% |
Relationships between endpoints
↥Index endpoint: DRUGADVERS_ADRENOCORTICAL_INSUFFICIENCY – Drug-induced adrenocortical insufficiency
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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