No definition available.
Congenital malformations of the respiratory system
EFO MESH Endpoint Browser PheWeb
Q17_CONGEN_MALFO_RESPI_SYSTEM
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
643 |
4. Check minimum number of eventsNone |
643 |
5. Include endpoints |
643 |
6. Filter based on genotype QC (FinnGen only) |
621 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q
- Name in latin
- Malformationes congenitae systematis respiratorii
Similar endpoints
↥List of similar endpoints to
Congenital malformations of the respiratory system
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of the respiratory system
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7047 | 3406 | 3623 |
| Only index persons | 4802 | 2461 | 2341 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.10 | 0.10 |
| Only index persons | 0.09 | 0.09 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 10.90 | 21.32 | 0.82 |
| Only index persons | 30.26 | 46.96 | 12.69 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 621 | 370 | 251 |
| Unadjusted period prevalence (%) | 0.12 | 0.13 | 0.11 |
| Median age at first event (years) | 50.68 | 53.04 | 47.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 643
- Matched controls
- 6425
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UGC12
NOMESCO Finland
Flexible bronchoscopy
18.2
259.6
250
217
Q32.21
ICD-10 Finland
Secondary congenital bronchomalacia
2358.3
183.4
169
*
Q32.0
ICD-10 Finland
Congenital tracheomalacia
+∞
120.7
112
*
R03BB04
ATC
tiotropium bromide; inhalant
7.4
93.9
160
275
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
7.6
75.0
118
184
UGC02
NOMESCO Finland
Rigid bronchoscopy
34.5
70.1
45
14
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.1
67.5
134
264
J45.9
ICD-10 Finland
Asthma, unspecified
4.3
64.5
235
764
J45.1
ICD-10 Finland
Nonallergic asthma
5.5
62.5
143
320
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.5
57.6
178
507
J47
ICD-10 Finland
Bronchiectasis
13.6
56.1
54
43
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
12.4
55.8
57
50
R03DC03
ATC
montelukast; oral
4.0
55.8
210
690
J46
ICD-10 Finland
Status asthmaticus
10.8
55.0
62
63
Q31.40
ICD-10 Finland
Congenital laryngomalasia
561.8
53.3
52
*
R03AC02
ATC
salbutamol; inhalant
3.9
51.7
487
2840
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.7
50.9
220
788
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.5
50.3
248
966
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.2
46.0
383
2015
Q32.20
ICD-10 Finland
Congenital bronchomalacia
+∞
45.3
43
*
XG410
NOMESCO Finland
Flow-volume spirometry
6.9
45.0
74
119
J98.0
ICD-10 Finland
Diseases of bronchus, not elsewhere classified
69.0
44.9
51
8
Q34.1
ICD-10 Finland
Congenital cyst of mediastinum
+∞
44.3
42
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.0
43.3
104
239
R03BA08
ATC
ciclesonide; inhalant
4.8
43.2
109
261
WX704
NOMESCO Finland
Intubation
5.0
41.7
98
221
R05
ICD-10 Finland
Cough
3.2
40.1
228
948
R03DA04
ATC
theophylline; systemic, rectal
6.5
39.8
69
117
R06.0
ICD-10 Finland
Dyspnoea
3.1
39.3
241
1045
R03BA05
ATC
fluticasone; inhalant
3.2
38.4
213
870
R03AK08
ATC
formoterol and beclometasone; inhalant
6.5
38.3
66
111
H02AB06
ATC
prednisolone; systemic
2.9
37.1
364
2017
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
8.0
35.7
50
67
R03BB01
ATC
ipratropium bromide; inhalant
6.7
35.3
59
96
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.8
34.9
68
129
J45.8
ICD-10 Finland
Mixed asthma
7.0
32.8
52
80
WX725
NOMESCO Finland
Noninvasive ventilation
5.2
32.3
71
150
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
5.7
31.9
63
121
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.0
31.0
178
731
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
30.7
194
838
R96
ICPC
Asthma
3.8
30.5
104
309
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
6.6
30.0
50
81
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.0
29.9
160
630
R03BA02
ATC
budesonide; inhalant
3.0
29.9
173
712
Q31.3
ICD-10 Finland
Laryngocele
+∞
28.3
27
*
Q33.2
ICD-10 Finland
Sequestration of lung
+∞
28.3
27
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.7
28.3
199
905
G47.3
ICD-10 Finland
Sleep apnoea
2.8
27.7
182
798
J01MA14
ATC
moxifloxacin; systemic
3.9
27.5
90
259
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.7
27.1
66
152
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.3
25.8
109
371
R03AK07
ATC
formoterol and budesonide; inhalant
2.7
25.2
171
758
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.9
25.1
80
226
R02
ICPC
Shortness of breath/dyspnoea
3.1
24.7
120
443
Q30.8
ICD-10 Finland
Other congenital malformations of nose
+∞
24.1
23
*
R03AC12
ATC
salmeterol; inhalant
4.8
24.1
57
128
GD1AD
NOMESCO Finland
Thorax CT examination
4.4
23.5
63
156
WX402
NOMESCO Finland
General anaesthesia
2.5
23.0
195
957
Q33.08
ICD-10 Finland
Congenital cystic lung
+∞
22.0
21
*
R03BC03
ATC
nedocromil; inhalant
3.8
22.0
71
202
R03AC03
ATC
terbutaline; inhalant
2.8
21.6
122
488
R03AK11
ATC
formoterol and fluticasone; inhalant
6.7
21.5
35
55
UDQ12
NOMESCO Finland
Flexible laryngoscopy
4.0
21.4
65
177
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
21.3
149
665
TPH07
NOMESCO Finland
Cathetrisation of artery
2.9
20.8
109
418
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
20.8
219
1176
XG474
NOMESCO Finland
Exhalation nntrogen oxide
5.1
20.6
45
94
R03BA01
ATC
beclometasone; inhalant
2.9
20.5
111
433
R04.2
ICD-10 Finland
Haemoptysis
5.7
18.5
35
64
J01FA06
ATC
roxithromycin; oral
2.1
18.5
262
1569
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
16.8
18.5
29
18
R06.2
ICD-10 Finland
Wheezing
3.7
18.3
61
177
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
17.8
107
440
Q32.10
ICD-10 Finland
Other congenital malformations of trachea
+∞
17.8
17
*
WX892
NOMESCO Finland
Monitored bed care
3.1
17.5
81
289
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
19.3
17.4
26
14
SPAT1059
SPAT
Spirometry at the office
3.9
17.3
53
145
C03CA01
ATC
furosemide; systemic
2.2
17.1
193
1052
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.3
16.8
69
229
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
16.8
200
1113
R06.1
ICD-10 Finland
Stridor
36.1
16.8
21
6
Q32.4
ICD-10 Finland
Other congenital malformations of bronchus
+∞
16.7
16
*
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.4
16.4
61
190
J01MA12
ATC
levofloxacin; systemic
2.4
16.4
127
589
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.1
16.3
35
72
H02AB04
ATC
methylprednisolone; systemic
2.6
16.2
110
479
R99
ICPC
Respiratory disease other
7.0
16.2
25
37
R05
ICPC
Cough
2.1
16.1
204
1160
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.7
15.9
92
370
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
15.7
388
2783
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.4
15.7
40
95
Q31.1
ICD-10 Finland
Congenital subglottic stenosis
+∞
15.7
15
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
15.4
64
214
N03AX16
ATC
[U] pregabalin
2.2
15.4
162
855
R03AK03
ATC
[U] fenoterol and ipratropium bromide
3.9
15.3
46
124
SPAT1058
SPAT
PEF monitoring instruction
3.1
15.2
68
237
A02BC05
ATC
esomeprazole; systemic
2.0
15.0
261
1655
R01AD58
ATC
fluticasone, combinations; nasal
2.1
14.8
172
941
Q30.9
ICD-10 Finland
Congenital malformation of nose, unspecified
153.2
14.5
15
*
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
17.5
14.4
22
13
J45
ICD-10 Finland
Asthma
2.7
14.3
86
352
R03AC13
ATC
formoterol; inhalant
3.7
14.3
47
135
R49.08
ICD-10 Finland
Other specified dysphonia
5.1
14.2
30
61
TGC00
NOMESCO Finland
Bronchial lavation
5.0
14.1
31
65
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.4
13.8
35
83
AA1AD
NOMESCO Finland
CT of head and brain
2.1
13.7
174
981
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.4
13.7
50
154
J01FA10
ATC
azithromycin; systemic
1.9
13.7
408
3056
J96.1
ICD-10 Finland
Chronic respiratory failure
5.6
13.6
26
48
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.6
13.4
46
136
SPAT1263
SPAT
Sampling
1.9
13.2
280
1873
R01AD08
ATC
fluticasone; nasal
2.0
13.0
183
1068
J42
ICD-10 Finland
Unspecified chronic bronchitis
12.6
12.7
22
18
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
12.7
366
2686
Q30.0
ICD-10 Finland
Choanal atresia
+∞
12.5
12
*
Q33.6
ICD-10 Finland
Hypoplasia and dysplasia of lung
+∞
12.5
12
*
Q34.0
ICD-10 Finland
Anomaly of pleura
+∞
12.5
12
*
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.7
12.5
29
64
H02AB07
ATC
prednisone; oral
2.4
12.4
95
436
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
12.2
264
1768
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
12.1
56
199
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.9
12.1
60
222
WX720
NOMESCO Finland
Own respiration
3.5
12.0
42
126
F82
ICD-10 Finland
Specific developmental disorder of motor function
5.4
11.6
23
44
R95
ICPC
Chron obstructive pulmonary disease
4.8
11.5
26
56
Z93.0
ICD-10 Finland
Tracheostomy status
+∞
11.5
11
*
GBA32
NOMESCO Finland
Endoscopic dilatation of trachea
122.0
11.5
12
*
SPAT1301
SPAT
No procedures
1.9
11.4
211
1339
ZXD05
NOMESCO Finland
Urgent procedure
1.9
11.4
193
1191
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
11.4
170
1007
R06.5
ICD-10 Finland
Mouth breathing
2.5
11.3
77
334
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
11.2
105
524
N06AA09
ATC
amitriptyline; systemic
2.6
11.2
69
286
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.0
11.0
32
84
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
11.0
241
1608
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.0
10.9
31
80
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.3
10.7
28
68
ZXA10
NOMESCO Finland
Bilateral
2.0
10.7
136
761
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
10.6
64
262
R01AD09
ATC
mometasone; nasal
1.7
10.6
288
2040
R06.8
ICD-10 Finland
Other and unspecified abnormalities of breathing
4.9
10.5
23
48
J01MA02
ATC
ciprofloxacin; systemic
1.8
10.5
219
1437
Q32.11
ICD-10 Finland
Congenital tracheo-esophageal fissure
+∞
10.4
10
*
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
16.3
10.4
16
10
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
10.4
132
738
UGB02
NOMESCO Finland
Tracheoscopy
23.8
10.3
14
6
UKC02
NOMESCO Finland
Cystoscopy
2.2
10.1
91
446
N06AX11
ATC
mirtazapine; oral
1.8
10.1
208
1357
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.0
10.0
118
641
J01AA02
ATC
doxycycline; systemic
1.8
10.0
441
3551
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
9.9
159
960
R04
ICPC
Breathing problem other
3.4
9.8
36
111
DLD00
NOMESCO Finland
Reconstruction of cartilage of nose
26.5
9.8
13
5
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
9.8
62
260
R5140
NOMESCO Finland
Monitoring the use of the aid
2.3
9.7
78
364
5191A
ICD-9 Finland
Other diseases of respiratory system, Other diseases of trachea and bronchus, not elsewhere classified
55.8
9.7
11
*
A02BC02
ATC
pantoprazole; systemic
1.7
9.7
384
2989
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
9.7
171
1063
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
4.7
9.6
22
48
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
9.6
74
340
WX722
NOMESCO Finland
PEEP
2.9
9.5
46
168
UDQ02
NOMESCO Finland
Direct laryngoscopy
7.7
9.5
21
28
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
9.4
276
1976
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
9.4
88
437
A01AB09
ATC
miconazole; local oral
2.4
9.4
66
290
Q33.00
ICD-10 Finland
Solitary congenital cyst in the lungs
+∞
9.4
9
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
9.4
107
574
M50.3
ICD-10 Finland
Other cervical disc degeneration
4.8
9.3
21
45
A06AD11
ATC
lactulose; oral
2.1
9.3
91
460
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.3
9.3
35
110
J01CA04
ATC
amoxicillin; systemic
2.0
9.3
545
4720
SPAT1262
SPAT
Handing over of treatment supplies
2.0
9.3
107
576
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
9.3
89
447
C07AB07
ATC
bisoprolol; oral
1.7
9.3
265
1884
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
5.1
9.1
19
38
XQ845
NOMESCO Finland
Dermatoscopy
7.2
9.1
21
30
J38.6
ICD-10 Finland
Stenosis of larynx
37.2
9.0
11
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
9.0
103
552
DLD20
NOMESCO Finland
Rhinoplasty
24.4
8.9
12
5
N02AX02
ATC
tramadol; systemic, rectal
1.7
8.9
243
1701
XG413
NOMESCO Finland
Spirometry with oscillometry
7.0
8.9
21
31
R51.80
ICD-10 Finland
Headache
1.9
8.9
120
683
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.9
8.8
121
691
J41.0
ICD-10 Finland
Simple chronic bronchitis
10.9
8.8
16
15
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.8
8.8
46
175
SPAT1081
SPAT
Cardiorespiratory global assessment
3.1
8.7
37
125
ZXE20
NOMESCO Finland
More than three and less than five hours
2.0
8.7
98
523
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.0
8.6
106
583
UJF32
NOMESCO Finland
Coloscopy
1.8
8.6
151
933
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.2
8.6
71
336
R29
ICPC
Respiratory symptom/complaint other
2.5
8.5
53
220
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
7.5
8.5
19
26
C01DA14
ATC
isosorbide mononitrate; oral
2.1
8.5
81
406
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
8.5
152
945
GCA18
NOMESCO Finland
Bronchoscopic dilatation of bronchus
91.1
8.4
9
*
B01AA03
ATC
warfarin; systemic
2.0
8.4
102
559
I50.9
ICD-10 Finland
Heart failure, unspecified
2.2
8.4
78
387
Q33.9
ICD-10 Finland
Congenital malformation of lung, unspecified
+∞
8.3
8
*
GBB13
NOMESCO Finland
Revision of tracheostomy
+∞
8.3
8
*
C08CA01
ATC
amlodipine; oral
1.7
8.3
206
1400
R01AD12
ATC
fluticasone furoate; nasal
1.7
8.1
197
1330
N03AX12
ATC
[U] gabapentin; oral
2.0
8.1
102
565
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
17.4
8.1
12
7
A03FA02
ATC
cisapride; oral, rectal
2.5
8.1
53
226
205
Kela drug reimbursment
Chronic hypertension
1.8
8.0
138
846
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.0
7.9
34
116
A02BA02
ATC
ranitidine; systemic
1.9
7.9
114
661
A02BC01
ATC
omeprazole; systemic
1.7
7.9
156
995
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
7.9
134
818
R28
ICPC
Limited function/disability (R)
7.1
7.8
18
26
R4130
NOMESCO Finland
Speech therapy
2.9
7.7
35
123
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.2
7.7
66
316
DLD10
NOMESCO Finland
Reconstruction of cartilage and bone of nose
45.5
7.7
9
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
6.8
7.6
18
27
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
7.6
235
1683
WZC30
NOMESCO Finland
Teaching
1.9
7.6
102
577
GDC00
NOMESCO Finland
Lobectomy of lung
25.3
7.6
10
*
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
10.2
7.6
14
14
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
7.5
112
656
WX882
NOMESCO Finland
High dependency care
2.5
7.5
46
190
ZXA00
NOMESCO Finland
Right side
1.7
7.5
162
1058
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
7.4
186
1262
GBB96
NOMESCO Finland
Other tracheostomy procedure
80.9
7.4
8
*
R06AE07
ATC
cetirizine; oral
1.6
7.4
265
1963
XF600
NOMESCO Finland
Bloodpressure measurement
2.2
7.4
62
295
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
8.5
7.3
15
18
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.6
7.3
41
162
1240
FHL
Bronchoscopy
9.5
7.3
14
15
RF210, ,
NOMESCO Finland
3.5
7.3
25
74
R4110
NOMESCO Finland
Physiotherapy
1.7
7.3
187
1276
Q33.80
ICD-10 Finland
Congenital [cystic] adenomatoid malformation of lung
+∞
7.3
7
*
Q32.18
ICD-10 Finland
Other congenital malformations of trachea
+∞
7.3
7
*
Z43.0
ICD-10 Finland
Attention to tracheostomy
+∞
7.3
7
*
J98.8
ICD-10 Finland
Other specified respiratory disorders
+∞
7.3
7
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.8
7.3
36
133
J01FA09
ATC
clarithromycin; systemic
1.6
7.3
197
1363
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
4.6
7.2
17
38
R03DC01
ATC
zafirlukast; oral
4.6
7.2
17
38
FM2CE, ,
NOMESCO Finland
3.3
7.2
27
85
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
3.3
7.2
26
80
XG466
NOMESCO Finland
Sleep oxymetry
3.4
7.2
25
75
N06AX21
ATC
duloxetine; oral
2.0
7.2
75
389
A02BC03
ATC
lansoprazole; oral
1.7
7.2
160
1053
UDC00
NOMESCO Finland
Ear microscopy
2.2
7.2
61
292
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
20.3
7.1
10
5
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
7.1
240
1749
A01AB04
ATC
amphotericin B; local oral
2.8
7.1
36
135
A03CA02
ATC
clidinium and psycholeptics; oral
2.8
7.1
36
135
I50.0
ICD-10 Finland
Congestive heart failure
2.5
7.1
43
177
J20
ICD-10 Finland
Acute bronchitis
2.1
7.0
70
356
R50.9
ICD-10 Finland
Fever, unspecified
1.8
7.0
118
716
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
7.0
70
357
M54.4
ICD-10 Finland
Lumbago with sciatica
1.9
7.0
102
593
61
HP
Catheterization and pressure measurement of the left side of the heart
5.9
7.0
18
31
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
5.9
7.0
18
31
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.5
6.9
23
67
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.3
6.9
25
77
J01DB01
ATC
cefalexin; oral
1.7
6.9
497
4306
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.5
6.8
44
186
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.7
6.8
35
132
7862A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Cough
11.1
6.8
12
11
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.7
6.8
37
144
R09
ICPC
Sinus symptom/complaint
2.2
6.8
59
285
RK290, ,
NOMESCO Finland
16.9
6.8
10
6
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
4.0
6.7
19
49
J21.90
ICD-10 Finland
Acute obstructive bronchitis in children
2.8
6.7
32
116
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
6.7
127
797
C03DA01
ATC
spironolactone; oral
2.0
6.6
72
378
R44
ICPC
Respiratory, Preventive immunization/medic
6.0
6.6
17
29
GBB00
NOMESCO Finland
Tracheostomy
7.9
6.6
14
18
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
6.6
63
315
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.2
6.6
58
281
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.9
6.6
84
467
SPAT1229
SPAT
Assessment of need for aid
2.4
6.6
45
196
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
8.8
6.6
13
15
R09.3
ICD-10 Finland
Abnormal sputum
8.8
6.6
13
15
N05CF01
ATC
zopiclone; oral
1.6
6.5
179
1238
XG405
NOMESCO Finland
Education on PEF monitoring
5.4
6.5
18
34
J01FF01
ATC
clindamycin; systemic
1.7
6.5
153
1019
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.1
6.5
62
311
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.3
6.5
46
204
DQW99
NOMESCO Finland
Other operation on larynx
70.5
6.4
7
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
6.4
75
405
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.6
6.4
36
143
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.1
6.4
60
299
R49.01
ICD-10 Finland
Functional dysphonia
3.2
6.4
25
81
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.1
6.4
62
313
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
6.6
6.4
15
23
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.8
6.4
31
114
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
3.7
6.3
20
56
A28
ICPC
Limited function/disability NOS
1.8
6.3
99
587
I31.3
ICD-10 Finland
Pericardial effusion (noninflammatory)
18.2
6.3
9
5
Q30.3
ICD-10 Finland
Congenital perforated nasal septum
+∞
6.3
6
*
Q31.48
ICD-10 Finland
Other congenital laryngeal warts
+∞
6.3
6
*
Q34.88
ICD-10 Finland
Other specified congenital malformations of respiratory system
+∞
6.3
6
*
DQD40
NOMESCO Finland
Plastic repair of larynx
+∞
6.3
6
*
DHA10
NOMESCO Finland
Biopsy of cavity of nose
7.1
6.2
14
20
SPAT1360
SPAT
Extensive global examination
2.4
6.2
43
188
AN1
HP
Coronary angiography
2.1
6.2
57
281
J34.2
ICD-10 Finland
Deviated nasal septum
2.6
6.2
36
145
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
6.2
104
631
B01AB05
ATC
enoxaparin; parenteral
1.6
6.1
170
1177
R05CB03
ATC
carbocisteine; oral
3.7
6.1
19
53
SAA04
NOMESCO Finland
Special examination of mouth
2.2
6.1
51
243
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
3.3
6.0
22
68
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
6.0
144
960
R05FA02
ATC
opium derivatives and expectorants; systemic
1.5
6.0
213
1558
XA800
NOMESCO Finland
Neuropsychological investigation
2.3
6.0
45
204
L28
ICPC
Limited function/disability (L)
1.8
6.0
99
596
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
97
145
7.69
63.66
3.7
2.6
—
—
—
0
0
162
409
4.95
61.36
2.0
1.4
116.01
203.55
u/ml
0.78
151
372
75
106
7.87
51.43
1.4
1.4
—
—
—
0
0
125
362
4.04
38.46
4.5
3.8
138.32
206.51
ng/l
1.54
114
332
41
47
9.24
33.09
1.6
1.4
1.74
8.06
u/ml
1.23
31
30
92
264
3.90
28.29
14.6
11.7
—
—
—
0
0
151
623
2.86
25.56
2.7
1.9
—
—
—
0
0
183
844
2.63
24.85
3.0
1.9
—
—
—
0
0
147
616
2.79
24.04
2.7
1.9
—
—
—
0
0
410
2772
2.32
22.72
9.9
7.6
28.33
30.94
%
4.63
397
2641
406
2739
2.31
22.54
9.6
7.4
57.04
53.97
%
5.29
391
2607
132
550
2.76
21.65
13.1
8.8
1.61
0.99
mmol/l
1.42
120
453
453
3237
2.35
21.40
11.7
10.5
4.28
3.89
e9/l
2.51
405
2770
34
53
6.71
21.09
4.0
3.5
—
—
—
0
0
339
2170
2.19
20.80
18.5
12.8
1.19
1.22
inr
0.23
86
626
119
485
2.78
20.28
3.8
3.5
9.40
9.40
g/l
0.00
114
451
64
183
3.77
19.61
2.0
1.9
—
—
—
0
0
41
84
5.14
19.21
1.8
1.7
—
—
—
0
0
63
181
3.75
19.17
2.5
1.9
—
—
—
0
0
379
2598
2.11
18.73
7.6
7.2
16.03
15.06
umol/l
0.23
365
2452
53
139
4.06
18.31
2.2
1.9
—
—
—
0
0
53
139
4.06
18.31
2.2
1.9
—
—
—
0
0
276
1692
2.10
18.26
4.5
3.8
27.89
33.52
u/l
2.93
270
1623
384
2670
2.09
17.95
16.1
9.1
1.22
1.22
mmol/l
0.73
344
2341
33
59
5.84
17.89
1.2
1.1
—
—
—
0
0
147
725
2.33
16.53
8.5
8.5
1.82
1.52
mmol/l
0.52
127
589
175
935
2.20
16.19
6.0
4.0
191.41
402.44
ng/l
1.09
133
718
320
2139
1.99
16.05
7.3
5.7
35.53
36.01
g/l
0.74
301
2014
44
112
4.14
15.81
2.1
2.0
—
—
—
0
0
44
112
4.14
15.81
2.1
2.0
—
—
—
0
0
197
1122
2.09
15.34
3.0
2.6
1.24
1.24
mg/l
0.00
149
877
220
1305
2.04
15.34
5.2
3.7
1160.25
1315.09
ng/l
0.17
199
1104
34
72
4.93
15.33
1.9
1.7
—
—
—
0
0
44
115
4.03
15.26
1.8
1.6
—
—
—
0
0
243
1506
1.98
14.88
3.1
2.7
145.89
61.45
u/l
0.44
230
1394
412
3051
1.97
14.84
10.9
6.2
6.64
6.53
mmol/l
0.43
397
2864
34
77
4.60
14.16
2.6
4.1
—
—
—
0
0
342
2474
1.81
12.25
15.6
9.0
1.21
1.22
mmol/l
2.65
319
2291
322
2312
1.78
11.60
3.5
2.8
—
—
—
0
0
473
3817
1.90
11.48
6.3
4.2
12.36
11.19
mm/h
0.96
457
3541
78
348
2.41
10.78
2.1
1.7
—
—
—
0
0
113
591
2.10
10.66
2.9
2.4
309.74
356.72
nmol/l
1.93
103
555
26
60
4.47
10.59
2.6
2.8
105.65
105.30
mmol/l
0.13
26
60
38
116
3.42
10.55
1.3
1.8
—
—
—
0
0
26
61
4.40
10.38
2.6
2.7
3.95
4.04
mmol/l
0.47
26
61
30
80
3.88
10.14
2.5
3.6
0.33
0.18
e9/l
1.26
23
57
30
80
3.88
10.14
2.4
3.7
646.13
506.09
e6/l
0.69
23
56
79
370
2.29
9.77
2.8
3.2
66.70
66.42
g/l
0.12
70
341
214
1421
1.76
9.67
2.5
2.1
172.36
221.13
u/l
0.72
200
1354
23
52
4.55
9.61
1.2
1.5
—
—
—
0
0
465
3836
1.76
9.26
9.6
7.2
86.05
89.83
u/l
0.70
448
3615
29
82
3.65
9.03
1.7
1.8
—
—
—
0
0
116
651
1.95
8.92
13.8
9.6
1.63
1.35
mmol/l
0.43
91
483
23
56
4.22
8.77
1.9
1.3
—
—
—
0
0
102
553
2.00
8.65
4.9
5.0
235.66
284.22
u/l
2.03
97
531
332
2543
1.63
8.41
5.3
3.8
0.00
0.01
estimate
0.50
45
437
258
1865
1.64
8.20
5.4
3.8
—
—
—
0
0
47
189
2.60
8.08
1.2
1.3
—
—
—
0
0
326
2508
1.61
7.95
5.4
3.8
0.02
0.00
estimate
0.42
53
474
38
138
2.86
7.93
1.7
1.9
—
—
—
0
0
43
168
2.67
7.83
3.3
2.1
1.42
2.96
ug/l
0.43
37
156
134
823
1.79
7.70
3.2
2.5
13.16
13.26
umol/l
0.05
124
770
11
6
18.60
7.62
3.8
1.5
35.36
42.17
umol/l
—
11
6
64
306
2.21
7.52
2.1
1.4
—
—
—
0
0
290
2196
1.58
7.39
3.3
2.7
77.56
76.31
nmol/l
0.35
270
1988
236
1708
1.60
7.26
5.0
3.6
30.59
55.88
ng/l
0.57
156
1144
323
2515
1.57
7.24
7.8
5.2
0.00
0.00
estimate
-0.00
49
453
57
264
2.27
7.23
6.5
8.7
0.61
0.65
%
0.43
57
264
48
206
2.44
7.23
1.0
1.1
—
—
—
0
0
188
1290
1.64
7.16
2.6
2.4
3.00
3.01
mg/l
0.01
165
1117
256
1894
1.58
7.14
5.0
3.7
—
—
—
0
0
585
5309
2.12
7.10
31.1
16.3
139.65
139.60
mmol/l
0.18
578
5178
27
86
3.23
7.05
1.3
1.4
—
—
—
0
0
85
464
1.96
7.03
6.9
5.3
75.80
69.92
ng/l
0.33
77
431
35
131
2.77
6.93
9.9
8.7
203.00
329.45
iu/ml
—
8
20
585
5321
2.09
6.86
31.4
16.4
3.98
3.98
mmol/l
0.15
578
5175
189
1314
1.62
6.78
4.5
3.8
9.13
22.23
mg/mmol
0.46
122
834
29
101
2.96
6.54
1.8
1.7
—
—
—
0
0
133
853
1.70
6.49
9.0
6.5
0.83
0.81
mmol/l
0.80
124
811
580
5297
1.96
6.14
28.3
13.7
21.94
22.46
mg/l
0.16
527
4074
13
17
7.77
6.14
3.8
6.9
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
36
146
2.55
6.12
15.6
7.5
0.36
0.35
u/ml
0.12
19
84
24
78
3.15
6.09
9.8
6.5
9.28
11.32
mg/l
1.04
24
72
164
1127
1.61
6.09
5.0
3.9
1.02
1.02
kg/l
0.97
35
175
142
942
1.65
6.07
1.8
1.7
54783167.86
14867035.40
pmol/l
0.32
115
787
114
716
1.72
5.98
3.4
2.6
22.00
22.36
%
0.08
92
631
119
759
1.70
5.89
3.4
2.5
2.37
2.41
g/l
0.34
110
708
441
3770
1.54
5.88
3.8
3.3
—
—
—
0
0
537
4810
1.70
5.85
30.1
17.3
14.41
14.63
%
0.51
531
4747
224
1669
1.52
5.78
5.4
3.7
16.83
94.15
e6/l
1.21
173
1261
206
1511
1.53
5.70
3.9
3.7
6.77
7.48
mmol/l
1.53
180
1306
92
554
1.77
5.58
15.8
10.3
7.74
7.35
mmol/l
0.25
83
531
294
2330
1.48
5.56
3.5
2.9
106.28
113.27
ug/l
0.26
280
2170
392
3302
1.48
5.36
4.3
3.5
43.65
45.67
u/l
0.27
380
3121
129
861
1.62
5.33
13.6
8.2
1.19
1.19
mmol/l
0.00
121
807
120
792
1.63
5.18
1.8
1.7
957.07
1208.59
nmol/l
3.39
94
590
526
4730
1.61
5.14
6.0
4.6
1.94
2.19
mu/l
0.48
503
4370
35
153
2.36
5.11
1.3
1.5
—
—
—
0
0
28
111
2.59
5.02
1.6
1.8
—
—
—
0
0
458
4006
1.49
4.98
5.0
3.8
14.77
14.72
pmol/l
0.20
435
3656
100
638
1.67
4.92
4.9
4.3
5.80
7.74
umol/l
0.88
89
552
30
126
2.45
4.79
1.0
1.1
—
—
—
0
0
123
833
1.59
4.76
1.2
1.3
44.63
33.19
iu/ml
0.17
32
271
27
108
2.56
4.76
3.3
3.1
16.70
16.55
%
0.06
21
62
203
1535
1.47
4.70
4.8
3.5
0.17
0.38
e6/l
2.51
157
1130
236
1839
1.45
4.66
2.1
1.9
96.87
96.84
pmol/l
0.00
118
952
57
313
1.90
4.65
2.6
1.7
—
—
—
0
0
32
141
2.33
4.61
1.9
1.3
—
—
—
0
0
32
141
2.33
4.61
1.9
1.3
—
—
—
0
0
176
1298
1.49
4.60
2.0
1.8
1.35
1.40
mmol/l
0.34
153
1121
133
926
1.55
4.56
4.3
3.4
4.04
2.24
e6/l
0.79
81
489
137
961
1.54
4.54
3.6
3.1
0.89
0.85
e6/l
0.07
82
517
34
156
2.24
4.47
2.2
2.2
—
—
—
0
0
166
1219
1.49
4.41
3.7
3.3
15194.11
5288.56
umol/l
0.81
145
1073
18
61
3.00
4.30
1.2
1.6
—
—
—
0
0
62
366
1.77
4.04
2.6
2.3
4.65
6.71
ug/l
1.12
51
322
11
22
5.06
4.01
10.4
7.7
—
—
—
0
0
166
1254
1.44
3.75
3.5
2.6
—
—
—
0
0
178
1362
1.42
3.75
1.7
1.6
2.04
2.11
g/l
0.24
125
773
584
5486
1.69
3.70
14.5
10.4
25.42
26.38
u/l
0.86
568
5298
114
807
1.50
3.58
1.2
1.3
20.54
11.97
u/ml
0.41
41
313
167
1273
1.42
3.57
1.8
1.7
—
—
—
0
0
60
366
1.70
3.51
4.2
4.0
1.24
1.23
mmol/l
0.49
52
320
26
119
2.23
3.48
2.7
4.5
27.19
103.83
mg/l
0.80
19
95
26
119
2.23
3.48
2.7
4.5
34.43
52.68
mg/l
0.29
19
94
147
1101
1.43
3.46
1.5
1.5
22.49
21.47
nmol/l
0.30
129
938
13
42
3.14
3.38
1.8
1.3
36205.17
63013.81
e6/l
—
6
21
47
271
1.79
3.34
1.6
1.8
35.26
23.20
iu/l
1.26
38
213
34
179
1.95
3.20
1.6
1.9
—
—
—
0
0
25
120
2.13
3.01
2.1
1.4
—
—
—
0
0
58
370
1.62
2.89
2.5
2.4
11.75
11.21
au/ml
—
6
21
504
4652
1.38
2.87
5.1
4.2
5.83
5.86
mmol/l
0.21
471
4254
10
28
3.61
2.79
1.1
1.2
86.50
77.32
%
—
10
28
7
14
5.04
2.73
3.3
2.9
—
—
—
0
0
24
119
2.05
2.69
1.2
1.2
—
—
—
0
0
69
468
1.53
2.67
5.1
3.3
—
—
—
0
0
143
1113
1.36
2.65
4.7
2.9
4.68
6.02
e6/l
0.69
125
1004
11
36
3.09
2.57
6.5
2.4
—
—
—
0
0
23
115
2.04
2.53
1.2
1.2
—
9.47
—
0
9
489
4527
1.33
2.47
4.3
3.9
1.26
1.28
mmol/l
0.20
456
4188
15
63
2.41
2.47
3.5
3.0
16.36
22.24
ug/l
1.24
15
63
162
1298
1.33
2.47
5.6
4.0
0.00
0.00
estimate
0.50
45
443
8
21
3.84
2.46
2.6
1.9
—
—
—
0
0
8
21
3.84
2.46
2.6
1.9
—
—
—
0
0
12
45
2.70
2.46
1.2
1.6
—
—
—
0
0
10
32
3.16
2.44
1.3
1.7
—
—
—
0
0
10
32
3.16
2.44
1.0
1.2
—
—
—
0
0
29
161
1.84
2.38
1.7
3.5
1793.96
1872.77
e6/l
0.01
23
119
29
161
1.84
2.38
1.6
3.4
54.32
5.73
e6/l
0.60
22
117
8
22
3.67
2.37
2.6
1.8
—
—
—
0
0
503
4686
1.33
2.36
4.9
4.2
1.42
1.48
mmol/l
2.22
467
4350
27
147
1.87
2.36
1.2
1.2
15.40
6.45
u/ml
—
6
25
29
163
1.81
2.30
2.1
1.9
284.66
202.69
u/ml
0.31
16
80
615
5948
1.76
2.29
36.5
20.2
263.55
256.88
e9/l
1.65
602
5740
202
1684
1.29
2.29
3.5
3.2
2.34
2.37
mmol/l
1.45
179
1498
506
4726
1.33
2.27
5.0
4.3
4.54
4.68
mmol/l
2.18
476
4407
9
29
3.13
2.23
2.4
1.7
—
—
—
0
0
9
29
3.13
2.23
2.4
1.7
—
—
—
0
0
615
5953
1.74
2.21
36.4
20.2
4.51
4.51
e12/l
0.08
603
5734
615
5956
1.73
2.16
37.2
20.5
133.65
134.40
g/l
0.64
610
5876
28
159
1.79
2.16
1.5
1.5
0.02
0.12
iu/ml
—
5
29
27
152
1.81
2.15
3.0
1.9
100.00
92.41
u/ml
—
5
19
101
769
1.37
2.14
2.1
2.5
142.45
105.22
ug/g
0.36
84
627
614
5947
1.70
2.11
38.1
20.6
38.82
39.95
%
2.63
541
5630
29
168
1.76
2.10
2.2
1.9
—
—
—
0
0
5
10
5.03
2.07
2.0
3.5
—
—
—
0
0
7
20
3.52
2.06
1.4
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
13
56
2.35
2.05
1.2
1.2
—
—
—
0
0
67
485
1.42
1.92
2.8
2.5
28.81
34.25
u/l
0.78
58
406
18
92
1.98
1.91
5.1
4.1
50.56
55.49
%
0.61
18
92
27
159
1.73
1.88
3.1
1.9
—
—
—
0
0
508
4786
1.29
1.87
5.4
4.7
2.66
2.78
mmol/l
2.19
466
4431
17
86
2.00
1.86
4.3
3.2
13.78
23.13
mu/l
0.48
17
81
31
191
1.65
1.84
1.6
2.1
8.44
8.26
u/l
0.03
23
138
6
17
3.55
1.84
1.2
1.2
—
—
—
0
0
6
17
3.55
1.84
5.2
9.5
—
—
—
0
0
12
53
2.29
1.81
2.1
1.6
—
—
—
0
0
12
53
2.29
1.81
2.1
1.6
—
—
—
0
0
12
53
2.29
1.81
2.1
1.6
—
—
—
0
0
17
88
1.96
1.76
4.1
3.6
4.25
4.14
e9/l
0.07
17
88
5
13
3.86
1.71
1.0
1.2
—
—
—
0
0
26
156
1.69
1.71
1.3
1.2
—
—
—
0
0
14
69
2.05
1.65
1.2
1.2
—
—
—
0
0
6
20
3.02
1.58
1.0
1.0
173.83
157.25
g/l
—
6
20
6
20
3.02
1.58
1.2
1.1
—
—
—
0
0
7
26
2.71
1.58
1.4
1.7
—
—
—
0
0
29
184
1.60
1.56
3.8
1.9
—
—
—
0
0
21
122
1.74
1.56
2.8
2.2
0.00
0.04
g/l
0.50
21
114
7
27
2.61
1.51
1.4
1.7
—
—
—
0
0
20
116
1.75
1.50
1.2
1.1
0.98
8.49
u/ml
3.08
14
60
27
171
1.60
1.48
1.6
1.4
296.47
308.54
ug/g
0.12
17
97
11
52
2.13
1.45
1.3
1.3
—
—
—
0
0
31
205
1.54
1.42
1.2
1.2
3.07
2.88
u/ml
0.03
19
141
463
4372
1.21
1.36
7.2
5.5
40.19
39.41
mmol/mol
1.00
432
4085
21
128
1.66
1.34
1.2
1.1
4.85
7.54
u/ml
0.33
15
78
16
90
1.80
1.33
1.5
1.2
—
—
—
0
0
51
378
1.38
1.33
1.2
1.3
83.04
163.25
iu/ml
1.63
18
152
18
106
1.72
1.30
4.9
4.0
26.73
27.24
mg/l
0.02
12
68
12
62
1.95
1.28
2.0
2.7
31.83
32.16
pg
0.11
12
62
17
101
1.70
1.20
1.6
1.6
—
—
—
0
0
26
173
1.52
1.19
3.4
1.7
—
—
—
0
0
5
20
2.51
1.15
3.8
3.8
—
—
—
0
0
8
40
2.01
1.12
1.3
1.7
128.39
144.50
ng/l
—
8
34
17
104
1.65
1.10
1.4
1.5
—
—
—
0
0
12
66
1.83
1.09
1.3
1.4
—
—
—
0
0
49
375
1.33
1.08
2.7
3.0
67.80
68.97
ml/min/173m2
0.06
20
155
9
46
1.97
1.04
2.3
1.2
—
—
—
0
0
5
22
2.28
1.03
2.2
1.9
—
—
—
0
0
44
571
0.75
1.03
5.0
4.3
36.34
31.95
%
1.51
29
393
18
114
1.59
1.03
3.1
2.3
0.00
0.00
g/l
-0.00
18
107
18
114
1.59
1.03
3.1
2.3
0.00
0.00
g/l
-0.00
18
107
32
436
0.72
1.03
2.0
1.7
—
—
—
0
0
7
34
2.07
1.03
1.1
1.0
—
—
—
0
0
9
47
1.93
1.02
1.4
1.3
—
—
—
0
0
9
49
1.85
0.99
1.1
1.1
—
—
—
0
0
9
49
1.85
0.99
1.1
1.1
—
—
—
0
0
5
23
2.18
0.98
4.4
5.8
—
—
—
0
0
5
23
2.18
0.98
1.0
1.2
—
—
—
0
0
5
23
2.18
0.98
4.8
5.9
—
—
—
0
0
29
207
1.42
0.98
1.8
1.8
—
—
—
0
0
9
50
1.81
0.97
1.1
1.1
—
—
—
0
0
9
50
1.81
0.97
1.1
1.1
—
—
—
0
0
9
50
1.81
0.97
1.1
1.1
—
—
—
0
0
0
32
0.00
0.95
0.0
1.2
—
4.32
—
0
27
58
469
1.26
0.88
2.9
4.2
11.18
31.19
ug/l
0.56
48
391
41
317
1.31
0.87
1.2
1.1
—
0.88
—
0
5
164
1473
1.15
0.82
1.4
1.5
1.17
2.12
u/ml
1.02
37
353
20
139
1.45
0.80
2.5
1.7
—
—
—
0
0
20
139
1.45
0.80
2.6
1.7
40.85
36.68
nmol/l
0.39
20
134
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
27
200
1.36
0.77
1.9
1.6
—
—
—
0
0
25
184
1.37
0.74
1.2
1.2
1.80
1.92
u/ml
0.03
17
129
25
184
1.37
0.74
1.2
1.2
0.99
0.95
u/ml
0.02
11
122
5
25
2.01
0.72
8.6
10.6
—
—
—
0
0
9
56
1.61
0.72
2.8
3.7
20.44
28.30
umol/l
—
9
56
11
68
1.63
0.72
1.1
1.1
—
—
—
0
0
12
76
1.59
0.72
2.8
1.7
—
—
—
0
0
16
110
1.46
0.68
1.1
1.1
0.04
0.75
u/ml
—
7
48
29
372
0.77
0.67
1.0
1.1
—
—
—
0
0
25
188
1.34
0.67
1.2
1.2
3.78
6.95
u/ml
0.65
14
132
34
268
1.28
0.66
2.4
1.9
—
—
—
0
0
10
62
1.62
0.65
1.2
1.0
—
—
—
0
0
22
163
1.36
0.65
1.3
1.4
—
—
—
0
0
5
29
1.73
0.64
1.2
1.1
—
—
—
0
0
53
629
0.83
0.64
2.6
2.8
0.65
0.73
ug/l
0.29
33
395
41
333
1.25
0.64
2.8
2.0
—
—
—
0
0
16
112
1.44
0.63
1.5
1.4
—
—
—
0
0
13
87
1.50
0.63
1.5
1.1
—
—
—
0
0
5
30
1.67
0.61
8.8
5.3
—
—
—
0
0
5
30
1.67
0.61
2.2
1.2
—
—
—
0
0
5
30
1.67
0.61
2.2
1.2
—
—
—
0
0
22
165
1.34
0.61
1.1
2.0
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
21.96
—
0
9
0
21
0.00
0.60
0.0
1.0
—
2.86
—
0
11
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
121
1091
1.13
0.58
4.7
4.6
4.84
2.21
ug/l
0.38
112
976
8
53
1.51
0.58
1.9
2.0
—
—
—
0
0
15
106
1.42
0.58
2.3
2.3
73.94
78.42
ug/min
—
8
58
24
185
1.31
0.56
2.0
2.4
21919.71
2904.29
u/l
—
8
64
6
37
1.63
0.55
3.5
1.7
—
—
—
0
0
24
186
1.30
0.55
2.0
3.1
5069.29
871.90
u/ml
0.37
17
158
17
125
1.37
0.54
1.4
1.2
—
—
—
0
0
10
66
1.52
0.52
1.1
1.1
—
—
—
0
0
10
66
1.52
0.52
1.2
1.3
0.52
0.56
nmol/l
—
10
61
7
45
1.56
0.49
1.1
1.2
—
—
—
0
0
21
163
1.30
0.48
6.2
4.5
1.95
1.36
mmol/l
0.62
21
157
7
46
1.53
0.48
1.1
1.2
—
—
—
0
0
7
46
1.53
0.48
1.4
1.1
—
79.00
—
0
6
32
263
1.23
0.48
4.2
2.8
19.79
52.17
u/ml
1.61
32
253
7
47
1.49
0.47
2.7
1.5
—
—
—
0
0
11
78
1.42
0.43
1.1
1.1
—
—
—
0
0
83
749
1.12
0.42
1.6
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
12.12
—
0
7
0
16
0.00
0.41
0.0
1.0
—
2.69
—
0
6
0
16
0.00
0.41
0.0
1.0
—
25.23
—
0
16
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
5
34
1.47
0.40
1.2
1.1
—
—
—
0
0
6
41
1.47
0.36
1.3
1.0
—
—
—
0
0
6
47
1.28
0.32
1.2
1.5
—
—
—
0
0
92
854
1.09
0.29
5.4
4.1
20.35
21.61
%
0.33
42
367
57
626
0.90
0.29
3.1
2.3
—
—
—
0
0
59
537
1.11
0.28
8.2
6.4
—
—
—
0
0
19
158
1.21
0.28
2.4
1.4
—
—
—
0
0
8
65
1.23
0.27
1.0
1.0
—
—
—
0
0
89
835
1.08
0.23
2.9
2.8
2.45
2.45
mmol/l
0.19
72
737
14
168
0.83
0.23
1.9
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.02
—
0
7
5
43
1.16
0.21
1.2
1.0
—
—
—
0
0
13
153
0.85
0.18
1.8
1.4
—
—
—
0
0
7
87
0.80
0.14
2.0
4.1
8.90
3155.20
u/ml
—
7
82
20
182
1.10
0.11
1.3
1.4
162.86
269.18
miu/ml
—
7
83
6
57
1.05
0.08
1.3
1.5
—
—
—
0
0
5
60
0.83
0.08
1.2
1.4
—
—
—
0
0
7
64
1.09
0.08
1.3
1.2
5.40
7.49
mmol/l
—
7
52
18
166
1.09
0.07
1.3
1.2
—
—
—
0
0
9
88
1.02
0.07
2.2
1.4
—
—
—
0
0
9
88
1.02
0.07
2.2
1.4
—
—
—
0
0
9
88
1.02
0.07
2.2
1.4
—
—
—
0
0
448
4454
1.02
0.05
20.1
12.3
84.39
83.91
ml/min/173m2
0.15
366
3592
14
130
1.08
0.04
2.7
1.9
2.84
5.25
iu/l
—
8
44
18
170
1.06
0.04
1.3
1.2
—
—
—
0
0
10
93
1.08
0.02
3.6
4.6
502.00
393.63
umol/l
—
10
88
57
578
0.98
0.01
2.9
2.1
—
—
—
0
0
10
102
0.98
0.00
2.1
1.5
—
—
—
0
0
14
143
0.98
0.00
1.4
1.4
—
—
—
0
0
31
309
1.00
0.00
1.3
1.3
—
—
—
0
0
5
51
0.98
0.00
1.2
1.3
2.48
4.99
ug/l
—
5
44
7
75
0.93
0.00
1.3
1.5
0.17
0.27
nmol/l
—
7
57
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.9
—
55.46
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
15.40
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_RESPI_SYSTEM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_RESPI_SYSTEM | 1.645 [1.4, 1.93] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.609 |
During the follow-up period (1.1.1998 — 31.12.2019), 351 out of 2898 females with Q17_CONGEN_MALFO_RESPI_SYSTEM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_RESPI_SYSTEM | 1.793 [1.51, 2.13] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.048 |
During the follow-up period (1.1.1998 — 31.12.2019), 306 out of 3120 males with Q17_CONGEN_MALFO_RESPI_SYSTEM died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_RESPI_SYSTEM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.152% | 0.304% |
| 5 | 0.981% | 2.075% |
| 10 | 2.571% | 5.326% |
| 15 | 4.954% | 10.257% |
| 20 | 8.949% | 16.892% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_RESPI_SYSTEM – Congenital malformations of the respiratory system
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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