No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
92 |
4. Check minimum number of eventsNone |
92 |
5. Include endpointsNone |
92 |
6. Filter based on genotype QC (FinnGen only) |
86 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_RESPI_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q3[0-4]
- Name in latin
- Malformationes congenitae pulmonis/pulmonum
Similar endpoints
↥List of similar endpoints to
Congenital malformations of lung
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of the respiratory system
- Congenital malformations of the respiratory system
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 981 | 473 | 506 |
| Only index persons | 577 | 282 | 295 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 4.16 | 6.77 | 1.64 |
| Only index persons | 29.63 | 36.04 | 23.51 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 86 | 44 | 42 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 42.92 | 45.70 | 40.01 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 92
- Matched controls
- 920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
14.8
30.1
32
32
Q33.2
ICD-10 Finland
Sequestration of lung
+∞
29.8
27
*
Q33.08
ICD-10 Finland
Congenital cystic lung
+∞
21.7
20
*
Q33.6
ICD-10 Finland
Hypoplasia and dysplasia of lung
+∞
12.8
12
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.7
10.7
33
98
UGC12
NOMESCO Finland
Flexible bronchoscopy
10.6
9.9
19
22
Q33.00
ICD-10 Finland
Solitary congenital cyst in the lungs
+∞
9.5
9
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.9
9.5
53
238
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.6
9.1
26
72
Q33.9
ICD-10 Finland
Congenital malformation of lung, unspecified
+∞
8.5
8
*
GDC00
NOMESCO Finland
Lobectomy of lung
+∞
8.5
8
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
8.6
7.6
16
22
Q33.80
ICD-10 Finland
Congenital [cystic] adenomatoid malformation of lung
+∞
7.4
7
*
J45.1
ICD-10 Finland
Nonallergic asthma
4.5
6.3
17
44
Q34.1
ICD-10 Finland
Congenital cyst of mediastinum
+∞
6.3
6
*
GD1AD
NOMESCO Finland
Thorax CT examination
9.7
6.3
12
14
R03AC02
ATC
salbutamol; inhalant
3.2
6.2
64
386
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.0
6.0
16
31
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
11
23
5.28
4.02
1.0
1.7
—
—
—
0
0
8
11
7.84
3.95
1.0
1.5
—
—
—
0
0
10
21
5.21
3.67
1.0
1.8
—
—
—
0
0
87
740
4.23
3.48
12.6
14.2
4.01
3.98
mmol/l
0.37
87
727
8
16
5.36
3.12
3.1
1.9
—
—
—
0
0
38
226
2.16
3.11
7.5
9.1
1.00
1.15
inr
2.17
14
61
6
8
7.92
3.10
1.2
1.6
—
—
—
0
0
39
239
2.10
2.92
4.0
3.1
—
—
—
0
0
15
61
2.74
2.79
1.7
1.2
111.78
133.24
u/ml
0.17
15
55
7
14
5.31
2.78
1.0
1.9
—
—
—
0
0
7
14
5.31
2.78
1.0
1.9
—
—
—
0
0
5
6
8.72
2.78
1.2
1.5
—
—
—
0
0
7
15
4.95
2.65
1.0
2.1
—
—
—
0
0
7
15
4.95
2.65
1.0
2.1
—
—
—
0
0
49
336
1.98
2.63
3.5
3.4
0.00
0.00
estimate
—
7
54
5
7
7.47
2.58
4.0
3.4
—
—
—
0
0
48
332
1.93
2.46
3.5
3.4
0.00
0.00
estimate
—
5
58
10
33
3.27
2.44
1.3
1.4
—
—
—
0
0
48
333
1.92
2.43
5.8
4.8
0.00
0.00
estimate
—
7
58
22
115
2.20
2.42
1.5
3.7
4.58
1.84
e6/l
0.61
13
62
17
80
2.38
2.36
1.8
1.9
—
—
—
0
0
23
124
2.14
2.34
1.5
3.1
0.95
0.79
e6/l
0.11
14
70
6
14
4.50
2.19
1.0
1.6
—
—
—
0
0
44
311
1.80
2.00
7.2
11.5
1.22
1.22
mmol/l
0.07
44
297
5
11
4.74
1.96
1.0
1.9
—
—
—
0
0
5
11
4.74
1.96
1.8
1.4
—
—
—
0
0
45
322
1.78
1.95
2.1
2.6
—
—
—
0
0
19
102
2.09
1.94
8.4
14.5
25.85
24.86
mmol/l
0.65
19
102
7
22
3.36
1.92
1.6
1.4
—
—
—
0
0
26
158
1.90
1.89
1.6
2.5
—
—
—
0
0
6
17
3.70
1.87
1.0
1.6
—
—
—
0
0
5
12
4.34
1.85
1.6
1.2
—
—
—
0
0
12
54
2.41
1.83
2.7
3.5
—
—
—
0
0
24
147
1.86
1.69
2.4
2.6
2.29
1.14
mg/l
0.28
16
118
5
14
3.71
1.63
1.0
1.7
—
—
—
0
0
30
199
1.75
1.63
3.2
3.4
0.18
0.42
e6/l
0.79
24
146
15
79
2.07
1.60
1.8
1.9
—
—
—
0
0
5
15
3.46
1.54
1.0
1.1
—
—
—
0
0
26
168
1.76
1.54
2.4
3.5
0.00
0.00
estimate
—
6
56
18
104
1.91
1.50
1.9
2.0
—
—
—
0
0
15
84
1.94
1.37
2.1
7.7
23.27
23.45
mmol/l
0.09
15
84
13
69
2.03
1.36
5.1
13.1
0.41
1.09
mmol/l
0.35
13
52
29
201
1.65
1.32
1.6
2.7
11.54
31.33
ng/l
2.15
15
112
7
36
2.02
0.99
7.4
21.5
0.71
0.71
%
—
7
36
77
696
1.65
0.96
3.8
4.1
2.87
2.87
mmol/l
0.01
72
662
7
37
1.96
0.96
7.4
21.0
1.00
1.74
%
—
7
37
6
30
2.07
0.88
1.0
1.2
—
—
—
0
0
31
239
1.45
0.85
2.2
4.0
26.81
32.44
u/l
0.96
31
230
6
32
1.93
0.83
1.0
1.2
—
—
—
0
0
31
242
1.42
0.79
3.3
3.7
—
—
—
0
0
17
121
1.50
0.68
3.0
4.0
73.64
407.29
ng/l
1.36
11
87
5
28
1.83
0.67
1.8
1.5
—
0.01
—
0
5
7
44
1.64
0.67
1.3
2.9
4.83
5.11
pmol/l
—
7
39
62
556
1.35
0.63
4.1
3.7
14.42
14.65
pmol/l
0.39
57
523
67
609
1.37
0.62
10.0
10.9
90.85
89.89
ml/min/173m2
0.15
55
488
0
21
0.00
0.61
0.0
2.4
—
—
—
0
0
26
210
1.33
0.53
1.7
1.8
—
—
—
0
0
9
65
1.43
0.52
3.0
6.6
—
—
—
0
0
11
149
0.70
0.44
1.6
2.3
2.37
2.90
mg/l
0.54
11
131
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
0.00
—
0
16
0
16
0.00
0.41
0.0
2.8
—
0.00
—
0
16
0
17
0.00
0.41
0.0
2.6
—
0.00
—
0
17
5
34
1.50
0.41
9.0
5.8
3.56
3.58
g/l
—
5
34
5
34
1.50
0.41
2.8
9.0
0.86
1.84
%
—
5
34
6
43
1.42
0.36
1.5
1.9
—
—
—
0
0
10
77
1.34
0.27
4.7
10.2
107.80
104.36
mmol/l
—
10
77
11
88
1.28
0.24
1.3
3.5
3.21
5.42
umol/l
1.93
11
75
5
42
1.20
0.22
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
101.80
—
0
10
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
6
47
1.30
0.21
3.3
1.9
—
—
—
0
0
19
166
1.18
0.20
3.7
3.9
1.50
1.70
ug/l
0.25
19
147
7
87
0.79
0.15
2.4
1.7
—
—
—
0
0
20
216
0.91
0.09
2.0
1.8
82.41
102.64
pmol/l
—
10
102
6
58
1.04
0.08
3.8
2.0
—
—
—
0
0
10
112
0.88
0.07
1.8
1.5
—
—
—
0
0
14
129
1.10
0.06
4.2
3.9
17.49
23.39
%
—
9
50
16
162
0.99
0.00
1.6
2.1
155.69
215.85
u/l
0.39
16
156
63
625
1.03
0.00
3.6
3.7
—
—
—
0
0
13
134
0.97
0.00
10.8
7.8
1.39
1.25
mmol/l
0.55
13
128
10
104
0.96
0.00
2.5
2.2
13.33
14.24
umol/l
—
10
99
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
9
91
0.99
-0.00
3.4
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
1.25
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.02
-0.00
1.4
3.5
26.71
28.77
u/l
—
7
53
9
99
0.90
-0.00
3.7
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
155.50
—
0
6
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_LUNG and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_LUNG.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_LUNG – Congenital malformations of lung
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data