Congenital malformations of nose

Q17_CONGEN_MALFO_NOSE

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Q30 Cause of death: ICD-10 — Q30 2 out of 7 registries used, show all original rules.	60
4. Check minimum number of events None	60
5. Include endpoints None	60
6. Filter based on genotype QC (FinnGen only)	56

Control definitions (FinnGen only)

Control exclude: Q17_CONGEN_MALFO_RESPI_SYSTEM

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: Q3[0-4]
Name in latin: Malformationes congenitae nasi

NAME	Q17_CONGEN_MALFO_NOSE
CONTROL_EXCLUDE	Q17_CONGEN_MALFO_RESPI_SYSTEM
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q30
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q30
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Congenital malformations of nose based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	653	364	284
Only index persons	530	302	228
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	22.66	24.80	19.44
Only index persons	28.41	31.22	24.69

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	56	37	19
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	36.54	40.24	29.34

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
60: Matched controls
600

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

Q30.8

ICD-10 Finland

Other congenital malformations of nose

+∞

25.9

Q30.9

ICD-10 Finland

Congenital malformation of nose, unspecified

+∞

16.4

DLD00

NOMESCO Finland

Reconstruction of cartilage of nose

+∞

14.1

Q30.0

ICD-10 Finland

Choanal atresia

+∞

13.0

DLD20

NOMESCO Finland

Rhinoplasty

147.1

11.9

DLD10

NOMESCO Finland

Reconstruction of cartilage and bone of nose

+∞

8.5

J34.2

ICD-10 Finland

Deviated nasal septum

8.7

7.1

Q30.3

ICD-10 Finland

Congenital perforated nasal septum

+∞

6.4

ZZG00

NOMESCO Finland

Graft of cartilage

+∞

6.4

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768797) Stomach Pathology biopsy report

3.21

3.15

1.9

1.4

—

(3010130) Cytomegalovirus IgG Ab [Units/volume] in Serum or Plasma

6.69

2.42

2.0

2.3

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

5.94

2.26

1.6

1.9

—

(3022145) Colonoscopy Study observation

2.65

1.72

1.3

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

2.72

1.66

1.4

2.3

14.30

12.71

nmol/l

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.21

1.62

2.5

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

3.31

1.47

6.0

26.4

1.11

1.12

mg/l

—

(3000494) Fungus identified in Specimen by Culture

2.21

1.45

2.8

2.0

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

3.11

1.38

1.4

1.2

—

(3022313) Gas panel - Capillary blood

2.66

1.34

5.7

11.0

—

(3027945) Reticulocytes/100 erythrocytes in Blood

2.48

1.33

6.0

5.6

1.93

1.63

—

(3026008) Bacteria identified in Urine by Culture

120

1.85

1.29

3.5

2.5

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

2.77

1.24

1.6

1.5

—

(3019225) pH of Specimen

2.42

1.15

18.3

4.3

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.38

1.05

2.2

2.0

—

(40768804) Tissue Pathology biopsy report

190

1.65

1.04

2.0

1.7

—

(3044640) Blood type and Crossmatch panel - Blood

137

1.69

1.02

3.5

2.4

—

(3012516) Albumin [Mass/volume] in Urine

1.77

0.99

6.0

2.6

12.24

23.69

mg/l

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.82

0.98

3.0

2.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

104

1.73

0.97

3.9

2.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

242

1.58

0.93

7.1

8.9

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

1.80

0.90

2.9

3.0

2255.80

222.68

ng/l

—

(3021960) Folate [Moles/volume] in Serum or Plasma

1.75

0.87

1.3

1.5

19.62

19.65

nmol/l

0.00

(3030467) Casts [#/volume] in Urine by Automated count

125

1.63

0.86

3.9

3.6

0.03

0.44

e6/l

1.85

(3000330) Specific gravity of Urine by Test strip

0.00

0.81

0.0

1.8

—

(3020682) Albumin/Creatinine [Ratio] in Urine

104

1.59

0.71

6.5

3.1

2.95

3.92

mg/mmol

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.93

0.70

2.8

10.9

26.00

24.19

mmol/l

—

(3023368) Bacteria identified in Blood by Culture

1.60

0.69

6.7

4.8

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.79

0.65

1.0

1.3

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.61

0.0

1.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.79

0.60

2.3

2.9

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.74

0.59

15.2

14.9

26.27

25.22

mmol/l

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.59

0.58

1.9

1.5

—

(3000991) Gas panel - Venous blood

1.69

0.57

24.0

12.5

—

(40758558) Short blood count panel - Blood

138

1.43

0.54

2.7

8.9

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.51

0.52

3.2

2.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

149

1.40

0.50

7.1

3.7

—

(3041096) Erythrocytes [Presence] in Urine by Automated

125

0.67

0.50

5.1

2.7

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

462

1.49

0.47

4.3

3.8

5.75

5.74

mmol/l

0.03

431

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

430

1.43

0.46

12.8

9.7

88.59

89.67

ml/min/173m2

0.11

339

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

504

0.69

0.46

17.8

12.4

24.52

20.29

mg/l

0.32

364

(3001122) Ferritin [Mass/volume] in Serum or Plasma

200

1.33

0.43

3.1

3.0

85.34

90.93

ug/l

0.10

190

(36304419) Bacteria [Presence] in Urine

125

1.38

0.43

4.1

3.6

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.42

0.0

1.4

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.3

—

60.79

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.40

0.0

2.8

—

65.32

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.38

0.40

2.0

1.5

—

(3042936) Bacteria identified in Isolate by Culture

1.36

0.39

2.1

—

(3002582) Erythrocytes [#/volume] in Urine

136

1.35

0.39

7.0

3.6

8.38

26.36

e6/l

0.93

108

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.34

0.39

3.1

2.0

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

175

0.74

0.37

6.3

3.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.44

0.36

1.7

1.4

—

(3012544) pH of Venous blood

1.34

0.34

12.7

7.3

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

1.40

0.32

1.8

3.3

2.44

2.43

mmol/l

—

(1761868) Lipid panel - Serum or Plasma

182

0.77

0.32

3.3

2.4

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

422

0.78

0.32

5.2

4.4

39.88

38.21

mmol/mol

0.43

399

(3019832) Treponema pallidum Ab [Presence] in Serum

1.31

0.29

1.6

1.5

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

251

0.80

0.28

12.8

5.4

6.72

6.43

mmol/l

0.16

230

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

143

1.26

0.27

1.9

1.8

93.50

91.25

pmol/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

116

1.27

0.25

2.6

1.8

—

(3022217) INR in Platelet poor plasma by Coagulation assay

164

1.23

0.24

22.9

7.9

1.17

1.13

inr

—

(3013512) EKG study

117

1.26

0.23

2.9

2.7

—

(4200892) Spirometry reversibility

1.24

0.22

1.4

1.6

—

(3024354) Oxygen [Partial pressure] in Venous blood

1.21

0.22

2.8

7.8

6.06

5.34

kpa

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.21

0.22

4.0

1.5

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.21

0.0

3.7

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.21

0.0

1.6

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.21

0.0

1.6

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

0.00

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.21

0.0

1.3

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

0.00

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.31

0.21

1.3

1.8

—

(3002032) Base excess in Venous blood by calculation

1.31

0.21

12.7

7.3

2.23

2.47

mmol/l

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

40.15

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

0.00

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.25

0.21

1.3

1.8

—

(3034770) Mitochondria Ab [Titer] in Serum

0.00

0.20

0.0

1.1

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.20

0.0

1.0

—

11.03

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.20

0.0

1.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

121

0.79

0.20

5.5

4.0

—

(3000492) Spirometry study

1.20

0.20

1.0

1.6

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

512

1.30

0.16

16.2

13.3

72.55

69.65

umol/l

0.51

512

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

103

1.21

0.15

1.8

2.4

0.81

0.78

mg/l

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

132

1.18

0.15

2.0

1.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

213

1.13

0.11

3.8

2.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.18

0.10

2.1

1.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.10

0.09

6.2

9.0

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.06

0.09

1.5

2.0

56.83

28.50

u/l

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

469

1.12

0.06

4.5

4.3

3.22

2.89

mmol/l

1.40

441

(3044889) 12 lead EKG panel

309

1.08

0.05

2.4

3.1

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

460

1.10

0.05

4.4

3.9

1.47

1.51

mmol/l

0.21

432

(3021589) Normoblasts [#/volume] in Blood

232

1.06

0.02

8.5

9.8

0.00

e9/l

-0.00

186

(3037467) Urinalysis macro (dipstick) panel - Urine

327

0.95

0.01

7.1

4.2

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

151

0.99

0.00

3.3

3.1

12.58

23.64

ng/l

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

447

1.03

0.00

4.2

3.6

1.26

1.23

mmol/l

0.12

417

(3003694) ABO and Rh group [Type] in Blood

135

1.05

0.00

1.4

1.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

415

1.04

0.00

3.5

3.4

—

(40761511) CBC panel - Blood by Automated count

525

1.08

0.00

11.9

9.6

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

-0.00

0.0

1.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.3

—

4.07

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

-0.00

0.0

4.4

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

18.0

—

1065.50

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.0

—

0.48

—

(40763324) Parainfluenza virus 1 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.1

—

769.29

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

1.5

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.3

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3044941) Cell count panel - Synovial fluid

0.00

-0.00

0.0

1.3

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.5

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

-0.00

0.0

2.0

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.4

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

-0.00

0.0

1.2

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.00

-0.00

3.5

1.7

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

0.96

-0.00

24.2

5.8

104.80

104.42

mmol/l

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.93

-0.00

1.3

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

21.2

—

2195.67

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.7

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

6.6

—

197.14

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.4

—

6.51

—

(3013005) Retinol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

2.04

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(3021788) Differential panel - Synovial fluid

0.00

-0.00

0.0

1.2

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.2

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.6

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.1

—

(3002079) Sodium [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.0

—

199.60

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3023410) Appearance of Cerebral spinal fluid

0.00

-0.00

0.0

7.0

—

(3023419) Bacteria identified in Sputum by Culture

0.00

-0.00

0.0

9.1

—

(3002256) Pathology report gross observation

0.91

-0.00

1.0

1.2

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(40763470) Parainfluenza virus 4 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(1616796) Gas panel - Central venous blood

0.00

-0.00

0.0

9.9

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

-0.00

0.0

1.0

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.0

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

-0.00

0.0

4.4

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.3

—

108.67

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

1.6

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

-0.00

0.0

1.1

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.1

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

-0.00

0.0

2.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.2

—

1.26

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

1.6

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

259.67

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_CONGEN_MALFO_NOSE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_CONGEN_MALFO_NOSE.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: Q17_CONGEN_MALFO_NOSE – Congenital malformations of nose

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Congenital malformations of nose

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints