No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
368 |
4. Check minimum number of eventsNone |
368 |
5. Include endpointsNone |
368 |
6. Filter based on genotype QC (FinnGen only) |
305 |
Control definitions (FinnGen only)
- Control exclude
- AB1_HIV
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Unspecified human immunodeficiency virus [HIV] disease
based on the number of shared cases.
Similar with more cases:
- Human immunodeficiency virus [HIV] disease
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2230 | 539 | 1557 |
| Only index persons | 1747 | 492 | 1255 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.02 | 0.04 |
| Only index persons | 0.04 | 0.02 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 39.14 | 34.60 | 41.16 |
| Only index persons | 39.53 | 34.14 | 41.64 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 305 | 51 | 254 |
| Unadjusted period prevalence (%) | 0.10 | 0.02 | 0.12 |
| Median age at first event (years) | 42.09 | 40.48 | 42.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 368
- Matched controls
- 3680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
WW200
NOMESCO Finland
Immunization
347.1
307.7
290
39
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
+∞
307.7
318
*
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
+∞
307.7
363
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
38.9
290.9
231
153
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
+∞
147.0
131
*
Z25.1
ICD-10 Finland
Need for immunization against influenza
20.0
124.7
107
74
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
+∞
119.4
108
*
Z3231
NOMESCO Finland
Registered nurse
9.8
108.4
238
581
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
8.4
65.1
101
159
Z2221
NOMESCO Finland
Medical doctor
5.1
52.6
180
584
B18.2
ICD-10 Finland
Chronic viral hepatitis C
14.2
44.2
42
33
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.2
40.3
79
155
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
7.4
38.9
62
98
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.1
38.2
232
1085
A63.0
ICD-10 Finland
Anogenital (venereal) warts
8.4
37.0
52
71
B23.0
ICD-10 Finland
Acute HIV infection syndrome
+∞
36.0
34
*
A51.0
ICD-10 Finland
Primary genital syphilis
357.5
33.5
33
*
A56.3
ICD-10 Finland
Chlamydial infection of anus and rectum
128.5
33.3
35
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.4
28.2
85
237
K02.9
ICD-10 Finland
Dental caries, unspecified
10.7
25.0
28
28
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
4.4
24.5
70
186
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
7.4
24.3
37
55
A54.6
ICD-10 Finland
Gonococcal infection of anus and rectum
+∞
24.2
23
*
A51.9
ICD-10 Finland
Early syphilis, unspecified
+∞
23.2
22
*
A54.0
ICD-10 Finland
Gonococcal infection of lower genitourinary tract without periurethral or accessory gland abscess
128.0
22.9
24
*
N05CD07
ATC
temazepam; oral
4.5
21.1
56
140
A53.9
ICD-10 Finland
Syphilis, unspecified
+∞
21.0
20
*
A54.5
ICD-10 Finland
Gonococcal pharyngitis
111.1
19.8
21
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.4
19.0
40
82
B20.6
ICD-10 Finland
HIV disease resulting in Pneumocystis jirovecii pneumonia
+∞
18.9
18
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
6.2
17.9
32
56
J05AB01
ATC
aciclovir; systemic
3.0
17.8
97
390
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
99.9
17.7
19
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.1
16.6
30
53
Z01.2
ICD-10 Finland
Dental examination
2.5
16.0
196
1166
QAJ99
NOMESCO Finland
Other aesthetic operations on skin of head or neck
+∞
15.7
15
*
ULA02
NOMESCO Finland
Kolposcopy
4.6
15.5
39
93
TAB00
NOMESCO Finland
Lumbar puncture
4.8
15.3
36
81
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
4.6
14.9
37
87
N05CF01
ATC
zopiclone; oral
2.5
14.6
131
670
R50.9
ICD-10 Finland
Fever, unspecified
2.9
14.6
82
332
Y25
ICPC
Fear sexually transm disease male
5.4
14.6
30
60
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.6
14.5
116
562
WX110, ,
SPAT
3.9
13.8
44
125
Z3226
NOMESCO Finland
Physiotherapist
2.8
13.6
81
338
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.6
13.5
47
142
EB1AA, ,
SPAT
3.7
13.5
45
132
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.5
13.3
106
510
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
10.2
12.9
25
26
B02.9
ICD-10 Finland
Zoster without complication
4.6
12.9
32
75
F43.29
ICD-10 Finland
Adaptation disorder UNS
5.4
12.9
26
51
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.9
12.7
68
267
A51.3
ICD-10 Finland
Secondary syphilis of skin and mucous membranes
72.4
12.7
14
*
B20.9
ICD-10 Finland
HIV disease resulting in unspecified infectious or parasitic disease
+∞
12.6
12
*
O98.5
ICD-10 Finland
Other viral diseases complicating pregnancy, childbirth and the puerperium
134.4
12.5
13
*
N06AB04
ATC
citalopram; systemic
2.5
11.7
88
409
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
11.5
111
578
ZXD35
NOMESCO Finland
Usual procedure
5.2
11.4
24
49
A01AB04
ATC
amphotericin B; local oral
6.0
11.1
20
35
C10AA07
ATC
rosuvastatin; oral
2.2
11.1
133
755
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
14.5
11.1
18
13
Z71.8
ICD-10 Finland
Other specified counselling
2.2
11.0
126
702
R4110
NOMESCO Finland
Physiotherapy
2.2
10.6
115
626
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
+∞
10.5
10
*
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
+∞
10.5
10
*
B90
ICPC
HIV-infection/AIDS
+∞
10.5
10
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
10.4
86
416
J01MA12
ATC
levofloxacin; systemic
2.5
10.3
78
362
UJF30
NOMESCO Finland
Ileoscopy through colon
3.0
10.3
49
179
TLC00
NOMESCO Finland
Insertion of intrauterine device
4.4
10.3
26
62
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.8
10.2
32
90
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
10.1
91
457
K02.2
ICD-10 Finland
Caries of cementum
4.2
10.0
27
68
WYA30, ,
SPAT
17.3
10.0
15
9
UJH02
NOMESCO Finland
Anoscopy
4.4
9.8
25
60
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
30.9
9.5
12
*
B20.0
ICD-10 Finland
HIV disease resulting in mycobacterial infection
+∞
9.4
9
*
K05.31
ICD-10 Finland
Periodontitis pronounced
2.7
9.4
57
238
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.9
8.9
44
164
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.0
8.8
41
148
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.8
8.7
27
75
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.0
8.7
25
66
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
2.3
8.6
75
370
Z2446
NOMESCO Finland
Social worker
3.2
8.6
35
117
D11
ICPC
Diarrhoea
2.5
8.6
56
242
SAA04
NOMESCO Finland
Special examination of mouth
3.6
8.5
29
86
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.4
8.4
62
284
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
11.1
8.4
15
14
0788C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Other specified diseases due to viruses and Chlamydiae[AIDS, IMMUUNIKATO]
+∞
8.4
8
*
A55
ICD-10 Finland
Chlamydial lymphogranuloma (venereum)
+∞
8.4
8
*
B20.3
ICD-10 Finland
HIV disease resulting in other viral infections
+∞
8.4
8
*
0788B
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Other specified diseases due to viruses and Chlamydiae[HIV-INFEKTIO,OIREISET TAUDINKUVAT]
+∞
8.4
8
*
Y71
ICPC
Gonorrhoea male
+∞
8.4
8
*
N05BA04
ATC
oxazepam; oral
2.1
8.3
96
529
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
14.9
8.3
13
9
N05BA01
ATC
diazepam; systemic, rectal
2.5
8.2
57
253
D06BB10
ATC
imiquimod; topical
3.9
8.2
24
64
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
2.8
7.8
40
152
J05AB11
ATC
valaciclovir; oral
2.4
7.6
56
255
Z3232
NOMESCO Finland
Midwife
3.2
7.5
31
104
C10AA03
ATC
pravastatin; oral
3.6
7.5
25
73
F15.5
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, psychotic disorder
13.7
7.4
12
9
N06AX11
ATC
mirtazapine; oral
1.9
7.4
129
817
B20.4
ICD-10 Finland
HIV disease resulting in candidiasis
+∞
7.3
7
*
B20.7
ICD-10 Finland
HIV disease resulting in multiple infections
+∞
7.3
7
*
B21.3
ICD-10 Finland
HIV disease resulting in other malignant neoplasms of lymphoid, haematopoietic and related tissue
+∞
7.3
7
*
B20.1
ICD-10 Finland
HIV disease resulting in other bacterial infections
+∞
7.3
7
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.5
7.2
25
75
-1, ,
NOMESCO Finland
1.9
7.2
134
864
S02.51
ICD-10 Finland
Fracture of tooth, open
2.5
7.2
47
203
ZX114
NOMESCO Finland
Intramuscular
9.0
7.1
14
16
P19
ICPC
Drug abuse
9.0
7.1
14
16
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.5
7.1
24
71
C10AA01
ATC
simvastatin; oral
0.4
7.0
31
737
R74
ICPC
Upper respiratory infection acute
1.8
6.9
128
824
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
2.4
6.9
50
227
N06AA12
ATC
doxepin; systemic
3.5
6.8
23
68
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
6.8
63
317
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
17.1
6.8
10
6
B07.9
ICD-10 Finland
Verruca simplex
3.6
6.7
22
64
ZXE00
NOMESCO Finland
One hour or less
1.8
6.7
133
874
OAB43, ,
SPAT
0.5
6.6
62
1095
TGC00
NOMESCO Finland
Bronchial lavation
5.5
6.5
18
34
3044A
ICD-9 Finland
Drug dependence, Amphetamine and other psychostimulant dependence
71.0
6.4
7
*
A52.1
ICD-10 Finland
Symptomatic neurosyphilis
71.0
6.4
7
*
B59
ICD-10 Finland
Pneumocystosis
71.0
6.4
7
*
TQW99
NOMESCO Finland
Other minor procedure on skin
3.7
6.4
20
56
TLC02
NOMESCO Finland
Simple extraction of IUD
6.7
6.4
15
23
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.3
6.4
18
536
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
8.4
6.4
13
16
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
6.3
34
133
B22.0
ICD-10 Finland
HIV disease resulting in encephalopathy
+∞
6.3
6
*
A51.5
ICD-10 Finland
Early syphilis, latent
+∞
6.3
6
*
A52.9
ICD-10 Finland
Late syphilis, unspecified
+∞
6.3
6
*
B23
ICD-10 Finland
Human immunodeficiency virus [HIV] disease resulting in other conditions
+∞
6.3
6
*
0788A
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Other specified diseases due to viruses and Chlamydiae[HIV-PRIMAARI-INFEKTIO JA OIREETON KANTAJAVAIHE]
+∞
6.3
6
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.9
6.2
16
28
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
351
372
183.60
307.65
14.6
7.2
0.93
1.02
mmol/l
8.41
351
355
358
12
10942.87
307.65
16.0
1.3
442.11
—
u/ml
—
226
0
327
19
1536.77
307.65
3.1
1.7
31.64
35.05
%
0.42
327
19
363
1409
116.86
130.60
15.2
6.6
—
—
—
0
0
304
881
15.09
121.63
5.1
3.4
34.95
116.74
e6/l
0.83
155
632
74
21
43.86
120.63
3.4
2.3
14.99
17.19
%
0.41
74
21
357
1348
56.15
109.55
19.1
6.1
0.79
0.70
%
3.08
357
1277
358
1392
58.84
105.55
19.2
6.1
2.85
2.92
%
0.33
358
1323
358
1400
58.30
104.68
19.3
6.4
8.98
8.63
%
2.27
358
1335
358
1419
57.04
102.63
18.8
6.0
50.42
57.43
%
34.61
358
1358
358
1443
55.50
100.11
19.3
6.1
35.99
27.87
%
47.28
358
1381
260
787
8.85
92.81
1.9
1.7
1.47
1.59
mmol/l
0.99
255
674
51
10
59.04
89.78
3.2
1.4
—
—
—
0
0
68
37
22.32
87.68
1.1
1.1
—
—
—
0
0
53
19
32.42
79.84
5.4
2.4
—
—
—
0
0
324
1365
12.49
78.48
4.2
2.9
0.00
0.00
estimate
-0.00
40
225
323
1357
12.29
78.43
7.1
4.0
0.00
0.00
estimate
-0.00
40
252
323
1363
12.20
77.86
4.2
2.8
0.00
0.00
estimate
0.50
41
258
96
119
10.56
75.82
4.9
1.8
—
—
—
0
0
46
12
43.67
75.74
5.5
1.8
—
—
—
0
0
363
2185
49.65
68.52
13.8
8.1
77.28
77.93
u/l
0.13
363
2080
96
147
8.48
63.32
5.1
1.9
—
—
—
0
0
193
707
4.64
47.25
3.4
2.8
0.26
0.42
e6/l
0.41
146
525
66
96
8.16
44.80
1.2
1.3
188.56
240.86
miu/ml
0.39
25
46
210
919
3.99
38.07
3.7
3.0
—
—
—
0
0
121
373
4.34
35.82
3.8
1.7
—
—
—
0
0
129
417
4.22
35.80
4.1
1.8
—
—
—
0
0
42
9
52.46
35.54
4.8
1.4
—
—
—
0
0
119
405
3.86
30.09
2.8
2.7
2.50
1.22
e6/l
0.45
59
206
32
30
11.59
29.95
2.1
1.7
—
—
—
0
0
122
435
3.70
28.62
2.8
2.6
0.96
0.85
e6/l
0.18
62
235
361
2934
13.11
24.38
8.7
4.0
5.99
5.99
mmol/l
0.02
361
2743
46
86
5.97
24.21
2.4
1.6
—
—
—
0
0
124
503
3.21
23.03
2.9
2.4
3.21
5.24
e6/l
0.63
119
454
47
106
4.94
20.03
1.5
1.6
1.24
1.61
g/l
1.72
42
96
353
2789
7.52
17.75
8.5
5.1
35.87
39.59
mmol/mol
15.28
353
2658
363
3128
12.81
17.54
8.9
4.1
1.28
1.33
mmol/l
2.82
363
2957
362
3131
10.58
16.53
9.0
4.1
4.54
4.72
mmol/l
4.27
362
2973
65
215
3.46
16.40
2.3
2.3
78.18
70.63
ml/min/173m2
1.00
37
91
363
3158
12.00
16.34
9.1
4.4
2.85
2.90
mmol/l
0.60
363
2988
40
94
4.65
16.16
1.2
1.7
0.02
0.11
iu/ml
0.69
20
17
160
870
2.48
15.86
5.1
3.5
8.80
9.10
mmol/l
0.31
152
750
28
50
5.98
15.32
4.0
3.4
2.92
4.30
e9/l
3.68
28
50
109
504
2.65
15.08
1.4
1.4
17.26
20.04
nmol/l
1.90
103
439
338
2668
4.27
15.02
28.6
15.2
13.59
14.47
%
5.13
338
2628
28
52
5.75
14.71
4.0
3.8
49.11
54.98
%
1.78
28
52
27
49
5.87
14.52
1.2
1.4
—
—
—
0
0
27
49
5.87
14.52
1.2
1.4
—
—
—
0
0
352
2906
5.86
13.63
22.4
11.2
88.28
88.77
ml/min/173m2
0.19
339
2398
75
305
2.83
13.16
3.4
4.1
220.15
248.89
u/l
0.87
75
290
41
118
3.78
12.64
1.4
1.4
—
—
—
0
0
354
3038
5.34
10.67
16.2
12.8
20.80
23.09
mg/l
0.70
285
2384
18
19
9.90
9.37
6.6
3.1
43.61
33.59
mu/l
0.46
18
19
13
8
16.77
8.61
1.6
1.0
—
—
iu/ml
—
0
0
13
8
16.77
8.61
1.2
1.0
—
—
—
0
0
30
91
3.50
8.54
2.9
3.1
—
—
—
0
0
17
20
8.85
8.40
1.1
1.0
—
—
—
0
0
97
542
2.07
8.07
2.2
2.0
2.61
3.10
mg/l
1.30
86
473
19
30
6.62
7.82
5.2
3.4
—
—
—
0
0
44
181
2.63
7.42
1.5
1.5
—
—
—
0
0
58
273
2.33
7.34
1.7
1.8
—
—
—
0
0
12
461
0.24
6.68
1.2
1.8
—
—
—
0
0
57
283
2.20
6.34
1.8
1.8
—
—
—
0
0
47
221
2.29
5.95
1.8
1.4
—
—
—
0
0
23
76
3.16
5.75
1.2
1.7
—
—
—
0
0
32
131
2.58
5.46
1.5
1.6
—
—
—
0
0
34
148
2.43
5.11
1.8
1.2
—
—
—
0
0
135
949
1.67
5.04
1.9
1.8
100.09
95.67
pmol/l
0.63
83
526
152
1129
1.59
4.42
6.3
7.6
1.21
1.20
mmol/l
0.21
145
1058
66
395
1.82
4.31
1.8
1.9
—
—
—
0
0
16
52
3.17
4.13
2.3
1.7
—
—
—
0
0
33
158
2.20
4.02
2.0
5.3
73.52
94.27
ng/l
1.03
33
152
46
253
1.94
3.89
3.0
3.8
0.23
1.92
mmol/l
1.38
34
212
58
345
1.81
3.86
2.3
3.3
8.82
8.41
umol/l
0.06
50
302
6
5
12.17
3.77
3.5
1.6
—
—
—
0
0
112
800
1.57
3.74
3.5
4.0
11.24
10.03
mg/mmol
0.13
79
543
10
22
4.64
3.45
1.8
2.9
—
—
—
0
0
133
1008
1.50
3.33
2.1
2.3
72.56
71.51
nmol/l
0.14
127
927
16
60
2.74
3.27
1.0
1.2
—
—
—
0
0
14
49
2.93
3.22
2.3
1.6
—
—
—
0
0
20
85
2.43
3.21
1.2
1.1
—
—
—
0
0
7
11
6.46
3.20
1.0
1.0
31.14
27.82
umol/l
—
7
11
157
1239
1.47
3.18
6.6
8.3
1.21
1.20
mmol/l
0.04
138
1073
58
367
1.69
3.12
2.1
1.7
947.75
1184.09
nmol/l
1.49
52
299
6
9
6.75
2.88
1.2
1.0
—
—
—
0
0
6
9
6.75
2.88
1.2
1.0
—
—
—
0
0
9
23
3.98
2.79
1.6
3.0
—
—
—
0
0
14
315
0.42
2.69
5.4
6.8
—
—
—
0
0
44
270
1.72
2.65
2.8
3.2
—
—
—
0
0
19
87
2.25
2.62
1.2
1.1
—
—
—
0
0
72
506
1.53
2.51
3.1
3.5
29.87
553.20
ng/l
1.92
52
367
212
2404
0.72
2.42
4.7
3.3
67.20
53.51
u/l
1.09
199
2289
15
64
2.40
2.42
2.9
3.6
4.73
5.06
kpa
1.57
15
64
10
33
3.09
2.37
1.1
1.5
—
—
—
0
0
10
33
3.09
2.37
1.1
1.5
—
—
—
0
0
10
33
3.09
2.37
1.1
1.5
—
—
—
0
0
8
24
3.38
2.19
1.1
1.0
—
—
—
0
0
8
24
3.38
2.19
1.1
1.0
—
—
—
0
0
97
1232
0.71
2.18
2.7
3.3
25.46
21.33
%
0.92
34
448
10
37
2.75
2.08
1.3
1.4
—
—
—
0
0
15
69
2.22
2.07
1.5
2.1
70.75
131.27
mg/l
0.28
15
53
144
1188
1.35
2.04
10.0
12.2
1.17
1.21
inr
0.21
33
361
80
599
1.43
2.03
2.0
2.2
1.66
1.51
%
1.23
66
535
83
1068
0.71
1.98
2.8
3.1
22.67
40.30
ng/l
1.04
43
672
9
33
2.77
1.94
1.1
1.5
—
—
—
0
0
137
1132
1.33
1.89
2.6
2.7
236.90
163.36
ug/l
0.54
130
1074
9
34
2.69
1.87
1.1
1.5
—
—
—
0
0
9
34
2.69
1.87
1.1
1.5
—
—
—
0
0
8
28
2.90
1.87
1.0
1.1
—
—
—
0
0
130
1545
0.75
1.81
3.4
3.6
2.19
1.78
ug/l
0.28
121
1432
6
18
3.37
1.75
1.0
1.2
—
—
—
0
0
14
68
2.10
1.72
1.2
2.0
—
1.17
—
0
10
100
802
1.34
1.67
5.1
3.6
2.36
2.35
mmol/l
0.24
84
730
14
69
2.07
1.67
1.4
2.1
59.92
31.10
mg/l
1.76
14
53
60
794
0.71
1.66
2.2
2.5
338.37
3633.03
umol/l
1.75
54
728
15
77
1.99
1.61
4.9
4.4
38.40
38.87
umol/l
0.02
15
71
7
26
2.72
1.59
3.1
2.4
—
—
—
0
0
11
50
2.24
1.58
1.5
1.4
—
—
—
0
0
5
128
0.38
1.52
3.0
3.6
25.80
25.19
mmol/l
—
5
123
7
27
2.62
1.52
1.1
1.2
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
12
59
2.07
1.45
1.3
1.5
—
—
—
0
0
13
68
1.95
1.35
2.5
1.4
31.13
7.53
e6/l
—
8
51
226
2056
1.26
1.33
2.8
3.4
13.77
14.61
pmol/l
6.55
212
1907
5
18
2.80
1.29
1.0
1.3
—
—
—
0
0
8
157
0.50
1.28
2.0
1.6
—
—
—
0
0
62
483
1.34
1.26
3.0
4.0
0.81
0.82
mmol/l
0.12
53
464
79
638
1.30
1.25
1.3
1.2
2.44
1.21
u/ml
—
8
201
5
19
2.65
1.22
1.0
1.1
675.60
255.72
iu/ml
—
5
19
11
57
1.96
1.18
1.4
1.5
—
—
—
0
0
11
57
1.96
1.18
1.4
1.5
—
—
—
0
0
11
57
1.96
1.18
1.5
1.5
—
—
—
0
0
11
57
1.96
1.18
1.4
1.5
—
—
—
0
0
321
3070
1.36
1.16
17.0
14.4
3.94
3.99
mmol/l
2.63
313
3004
11
58
1.92
1.13
1.5
1.6
—
—
—
0
0
15
88
1.73
1.13
1.0
1.1
—
—
—
0
0
7
137
0.50
1.12
2.4
2.5
0.56
0.67
%
—
7
137
10
52
1.95
1.07
2.0
1.7
—
—
—
0
0
80
663
1.26
1.04
1.9
1.8
2.94
1.10
mg/l
0.40
59
511
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
13
75
1.76
1.04
2.3
3.8
0.57
0.30
u/ml
—
5
38
5
22
2.29
1.03
1.2
1.0
—
—
—
0
0
5
22
2.29
1.03
1.0
1.6
3.08
4.13
mg/l
—
5
22
78
645
1.27
1.03
2.4
2.3
—
—
—
0
0
14
85
1.67
0.95
1.1
1.2
—
—
—
0
0
11
62
1.80
0.95
1.0
1.2
—
—
—
0
0
6
29
2.09
0.89
1.3
1.6
—
—
—
0
0
8
42
1.92
0.89
1.0
1.0
—
—
—
0
0
53
650
0.78
0.88
2.6
3.1
895.59
779.57
ng/l
0.17
48
525
13
80
1.65
0.85
1.1
1.2
239.17
232.32
u/ml
—
6
53
94
1080
0.83
0.85
5.4
2.8
—
—
—
0
0
317
3056
1.27
0.83
15.9
14.3
138.94
139.65
mmol/l
6.42
310
2991
6
33
1.83
0.79
1.2
1.4
—
—
—
0
0
5
98
0.50
0.79
1.0
1.1
—
3.37
—
0
13
9
53
1.72
0.76
1.1
1.9
—
—
—
0
0
9
53
1.72
0.76
1.1
1.9
—
—
—
0
0
5
25
2.01
0.73
1.0
1.1
—
—
—
0
0
5
25
2.01
0.73
1.2
1.0
—
—
—
0
0
11
68
1.64
0.72
2.1
2.7
21.57
24.33
mmol/l
1.76
11
68
7
40
1.76
0.71
1.0
1.2
—
—
—
0
0
114
1267
0.85
0.69
2.7
2.6
—
—
—
0
0
11
69
1.61
0.69
1.2
1.4
—
—
—
0
0
7
42
1.68
0.68
1.0
1.1
—
—
—
0
0
6
101
0.59
0.63
4.2
3.6
27.00
134.95
u/ml
—
6
84
238
2259
1.15
0.62
3.3
3.1
—
—
—
0
0
5
30
1.68
0.61
1.0
2.1
—
—
—
0
0
9
140
0.63
0.61
1.8
1.5
261.67
267.45
mu/l
—
9
132
0
20
0.00
0.60
0.0
1.2
—
1.06
—
0
7
6
35
1.73
0.58
1.0
1.1
—
—
—
0
0
6
36
1.68
0.57
1.7
1.1
—
—
—
0
0
48
407
1.21
0.54
2.9
3.3
2.43
2.43
mmol/l
0.04
33
358
9
64
1.42
0.52
1.0
1.2
—
62.83
—
0
6
68
598
1.17
0.52
1.5
1.5
—
—
—
0
0
6
40
1.51
0.52
1.0
1.8
—
—
—
0
0
6
40
1.51
0.52
1.0
1.8
—
—
—
0
0
9
65
1.39
0.51
1.0
1.3
—
—
—
0
0
84
926
0.88
0.45
2.2
2.5
0.71
0.66
ug/l
0.09
62
485
7
51
1.38
0.44
1.4
1.2
—
—
—
0
0
11
78
1.42
0.43
1.0
1.2
—
12.04
—
0
8
5
31
1.62
0.43
1.2
1.4
—
—
—
0
0
22
176
1.27
0.43
1.1
1.2
136.20
116.37
iu/ml
—
5
64
0
16
0.00
0.41
0.0
1.0
—
27.00
—
0
9
0
16
0.00
0.41
0.0
1.0
—
647.22
—
0
9
41
473
0.85
0.41
1.3
1.3
29.80
31.10
iu/ml
0.02
11
149
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.48
0.40
1.2
1.2
—
—
—
0
0
267
2587
1.12
0.40
4.0
3.9
1.85
1.83
mu/l
0.11
256
2419
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
5
35
1.43
0.39
1.0
2.0
—
—
—
0
0
0
19
0.00
0.39
0.0
2.8
—
—
—
0
0
13
98
1.34
0.38
1.5
1.6
—
—
—
0
0
31
363
0.84
0.37
15.7
8.8
105.03
104.07
mmol/l
0.57
31
363
38
437
0.85
0.37
1.3
1.2
5.03
7.98
u/ml
—
8
185
76
693
1.12
0.36
5.9
3.1
0.00
0.00
estimate
0.50
41
237
6
41
1.47
0.36
3.5
2.6
—
—
—
0
0
6
44
1.37
0.34
1.3
1.8
—
—
—
0
0
21
176
1.20
0.29
2.0
3.2
0.01
1.61
mmol/l
1.81
11
131
7
57
1.23
0.29
1.1
1.9
—
—
—
0
0
22
186
1.19
0.28
2.1
3.1
4.77
5.17
kpa
2.13
22
179
10
76
1.32
0.28
1.1
1.8
—
—
—
0
0
8
66
1.22
0.27
1.5
1.5
154.60
176.78
pmol/l
—
8
66
12
95
1.27
0.26
1.2
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
11.00
—
0
10
0
10
0.00
0.21
0.0
3.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
18.80
—
0
10
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
5
43
1.16
0.21
1.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
68.61
—
0
14
0
14
0.00
0.20
0.0
3.8
—
79.98
—
0
14
12
99
1.22
0.20
1.1
1.9
—
—
—
0
0
6
52
1.16
0.19
1.0
1.1
—
—
—
0
0
15
128
1.18
0.18
2.3
2.7
0.01
0.10
e6/l
3.18
15
122
7
62
1.13
0.17
1.1
1.1
—
—
—
0
0
7
63
1.11
0.17
1.0
1.7
—
—
—
0
0
6
78
0.77
0.15
1.3
1.8
—
—
—
0
0
10
119
0.84
0.15
1.2
1.4
13.06
19.32
iu/l
—
5
96
21
188
1.12
0.15
1.9
2.0
252.76
228.79
pmol/l
0.58
21
178
11
96
1.15
0.10
1.5
2.0
—
—
—
0
0
6
58
1.04
0.08
1.5
1.2
102.00
117.51
%
—
6
53
8
78
1.03
0.07
1.1
1.8
—
—
—
0
0
14
152
0.92
0.06
1.2
1.5
11.69
5.58
u/l
—
9
126
48
464
1.04
0.06
1.6
1.6
450.09
53606194.83
pmol/l
0.80
43
416
32
306
1.05
0.06
14.5
12.4
-0.86
1.09
mmol/l
1.25
22
254
10
91
1.10
0.04
1.5
1.8
—
—
—
0
0
14
146
0.96
0.00
1.1
1.0
—
—
—
0
0
16
156
1.03
0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
10.02
—
0
5
0
6
0.00
-0.00
0.0
3.0
—
51.65
—
0
6
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.8
—
43.63
—
0
8
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
1.25
—
0
9
6
61
0.98
-0.00
1.5
1.2
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.0
—
1.54
—
0
26
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_HIV_NOS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_HIV_NOS | 3.161 [2.63, 3.81] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 201 out of 1214 males with AB1_HIV_NOS died.
Mortality risk
Mortality risk for people of age
years, who have AB1_HIV_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.477% |
| 5 | No data | 3.193% |
| 10 | No data | 8.646% |
| 15 | No data | 14.951% |
| 20 | No data | 24.987% |
Relationships between endpoints
↥Index endpoint: AB1_HIV_NOS – Unspecified human immunodeficiency virus [HIV] disease
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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