No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
362 |
4. Check minimum number of eventsNone |
362 |
5. Include endpointsNone |
362 |
6. Filter based on genotype QC (FinnGen only) |
362 |
Control definitions (FinnGen only)
- Control exclude
- AB1_HIV
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Unspecified human immunodeficiency virus [HIV] disease
based on the number of shared cases.
Similar with more cases:
- Human immunodeficiency virus [HIV] disease
- Certain infectious and parasitic diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2230 | 539 | 1557 |
| Only index persons | 1747 | 492 | 1255 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.02 | 0.04 |
| Only index persons | 0.04 | 0.02 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 39.14 | 34.60 | 41.16 |
| Only index persons | 39.53 | 34.14 | 41.64 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 362 | 73 | 289 |
| Unadjusted period prevalence (%) | 0.11 | 0.02 | 0.13 |
| Median age at first event (years) | 41.35 | 40.13 | 41.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 323
- Matched controls
- 3230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
+∞
323.0
318
*
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
+∞
323.0
275
*
WW200
NOMESCO Finland
Immunization
508.0
295.5
258
25
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
47.4
158.5
201
108
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
+∞
130.2
116
*
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
+∞
103.9
94
*
Z25.1
ICD-10 Finland
Need for immunization against influenza
28.4
70.0
97
48
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.4
34.8
193
810
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
7.4
33.8
88
155
B23.0
ICD-10 Finland
Acute HIV infection syndrome
+∞
32.9
31
*
A56.3
ICD-10 Finland
Chlamydial infection of anus and rectum
176.9
31.3
32
*
A51.0
ICD-10 Finland
Primary genital syphilis
306.6
28.2
28
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
7.0
26.6
70
122
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
8.1
24.7
58
85
B18.2
ICD-10 Finland
Chronic viral hepatitis C
18.8
24.2
37
22
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
7.0
21.7
56
94
A54.6
ICD-10 Finland
Gonococcal infection of anus and rectum
+∞
20.0
19
*
A54.0
ICD-10 Finland
Gonococcal infection of lower genitourinary tract without periurethral or accessory gland abscess
212.4
19.8
20
*
A51.9
ICD-10 Finland
Early syphilis, unspecified
+∞
18.9
18
*
A54.5
ICD-10 Finland
Gonococcal pharyngitis
189.9
17.7
18
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
7.2
17.5
43
67
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
13.1
17.2
30
25
B20.6
ICD-10 Finland
HIV disease resulting in Pneumocystis jirovecii pneumonia
+∞
16.8
16
*
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
3.3
16.4
96
365
Z01.2
ICD-10 Finland
Dental examination
2.7
15.9
159
852
QAJ99
NOMESCO Finland
Other aesthetic operations on skin of head or neck
+∞
15.7
15
*
A53.9
ICD-10 Finland
Syphilis, unspecified
+∞
15.7
15
*
J05AB01
ATC
aciclovir; systemic
3.4
15.3
86
313
K02.9
ICD-10 Finland
Dental caries, unspecified
12.7
14.9
26
22
N05CF01
ATC
zopiclone; oral
2.8
14.4
114
525
O98.5
ICD-10 Finland
Other viral diseases complicating pregnancy, childbirth and the puerperium
+∞
13.6
13
*
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
145.8
13.6
14
*
C10AA07
ATC
rosuvastatin; oral
3.0
13.5
88
353
A51.3
ICD-10 Finland
Secondary syphilis of skin and mucous membranes
135.0
12.5
13
*
R50.9
ICD-10 Finland
Fever, unspecified
3.4
12.4
64
218
ULA02
NOMESCO Finland
Kolposcopy
5.4
12.3
37
75
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.0
12.0
77
304
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.6
11.9
42
102
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.8
11.9
86
368
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
11.5
62
216
B02.9
ICD-10 Finland
Zoster without complication
7.1
11.2
27
41
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
10.9
93
437
F43.29
ICD-10 Finland
Adaptation disorder UNS
7.4
10.8
25
36
K02.2
ICD-10 Finland
Caries of cementum
7.0
10.7
26
40
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
4.9
10.6
34
75
WYA30
SPAT
NA
113.5
10.5
11
*
R74
ICPC
Upper respiratory infection acute
2.4
10.5
107
551
B20.9
ICD-10 Finland
HIV disease resulting in unspecified infectious or parasitic disease
+∞
10.5
10
*
B90
ICPC
HIV-infection/AIDS
+∞
10.5
10
*
R4110
NOMESCO Finland
Physiotherapy
2.5
10.4
96
468
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
19.6
10.4
15
8
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
24.3
10.3
14
6
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
9.6
10.2
20
22
TAB00
NOMESCO Finland
Lumbar puncture
5.4
10.2
30
60
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.0
9.8
31
67
K05.31
ICD-10 Finland
Periodontitis pronounced
3.6
9.8
45
139
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
5.3
9.7
29
59
N06AB04
ATC
citalopram; systemic
2.6
9.7
77
345
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.6
9.6
24
39
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
102.9
9.5
10
*
N05BA04
ATC
oxazepam; oral
2.5
8.9
81
387
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.4
8.7
25
49
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
2.8
8.6
56
222
N05CD07
ATC
temazepam; oral
3.1
8.3
47
169
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
34.3
8.1
10
*
F15.5
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, psychotic disorder
22.7
8.1
11
5
J01MA12
ATC
levofloxacin; systemic
2.5
7.9
64
286
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
25.7
7.6
10
*
0788B
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Other specified diseases due to viruses and Chlamydiae[HIV-INFEKTIO,OIREISET TAUDINKUVAT]
+∞
7.3
7
*
B21.3
ICD-10 Finland
HIV disease resulting in other malignant neoplasms of lymphoid, haematopoietic and related tissue
+∞
7.3
7
*
B20.1
ICD-10 Finland
HIV disease resulting in other bacterial infections
+∞
7.3
7
*
B20.4
ICD-10 Finland
HIV disease resulting in candidiasis
+∞
7.3
7
*
B20.0
ICD-10 Finland
HIV disease resulting in mycobacterial infection
+∞
7.3
7
*
S02.51
ICD-10 Finland
Fracture of tooth, open
2.9
7.3
43
160
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
7.3
55
237
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
7.2
54
230
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
7.2
69
338
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.3
7.1
34
110
N06AX11
ATC
mirtazapine; oral
2.0
7.0
106
630
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.5
6.8
55
246
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
40.9
6.8
8
*
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
23.1
6.7
9
*
D07AA02
ATC
hydrocortisone; topical
2.6
6.6
51
221
A01AB04
ATC
amphotericin B; local oral
5.5
6.6
18
34
TQW99
NOMESCO Finland
Other minor procedure on skin
4.9
6.5
20
43
J05AB11
ATC
valaciclovir; oral
2.7
6.5
44
176
N05BA01
ATC
diazepam; systemic, rectal
2.5
6.5
50
217
B17.1
ICD-10 Finland
Acute hepatitis C
71.2
6.4
7
*
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
2.6
6.3
47
202
A52.1
ICD-10 Finland
Symptomatic neurosyphilis
+∞
6.3
6
*
B59
ICD-10 Finland
Pneumocystosis
+∞
6.3
6
*
B23
ICD-10 Finland
Human immunodeficiency virus [HIV] disease resulting in other conditions
+∞
6.3
6
*
A51.5
ICD-10 Finland
Early syphilis, latent
+∞
6.3
6
*
A55
ICD-10 Finland
Chlamydial lymphogranuloma (venereum)
+∞
6.3
6
*
0788C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Other specified diseases due to viruses and Chlamydiae[AIDS, IMMUUNIKATO]
+∞
6.3
6
*
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
27.2
6.3
8
*
D11
ICPC
Diarrhoea
2.6
6.3
44
183
-1
NOMESCO Finland
NA
1.9
6.3
117
746
C10AA01
ATC
simvastatin; oral
0.4
6.2
26
592
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
8.8
6.1
12
14
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.9
6.1
120
778
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
3.3
6.0
28
89
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
352
12
10583.47
307.65
16.1
1.3
361.4
—
u/ml
—
222
0
345
366
180.43
307.65
14.6
7.0
0.9
1.0
mmol/l
8.26
345
349
260
23
398.64
307.65
2.9
2.0
742.5
589.3
e6/l
0.63
37
12
352
1363
58.29
104.39
19.3
6.2
2.9
2.9
%
0.36
352
1289
352
1390
56.47
101.45
19.0
6.0
50.3
57.4
%
35.06
352
1327
352
1414
54.92
98.91
19.4
6.1
36.1
27.8
%
47.89
352
1347
256
771
8.92
92.04
1.9
1.7
1.5
1.6
mmol/l
1.07
251
660
65
37
21.19
82.02
1.1
1.1
—
—
—
0
0
53
19
32.51
79.86
5.4
2.4
—
—
—
0
0
318
1337
12.34
77.18
4.2
2.8
0.0
0.0
estimate
0.00
40
220
317
1329
12.14
77.13
7.1
3.9
0.0
0.0
estimate
0.00
40
247
317
1332
12.10
76.85
4.3
2.8
0.0
0.0
estimate
0.00
40
239
92
109
10.98
75.19
5.0
1.9
—
—
—
0
0
43
12
40.53
69.47
5.7
1.8
—
—
—
0
0
357
2152
48.68
67.19
13.9
8.0
77.5
77.8
u/l
0.05
357
2044
92
135
8.80
62.96
5.2
1.9
—
—
—
0
0
191
695
4.70
47.38
3.4
2.8
0.3
0.3
e6/l
0.20
144
513
50
9
64.15
43.69
3.2
1.4
—
—
—
0
0
62
92
7.93
41.28
1.2
1.3
171.0
244.4
miu/ml
0.56
22
45
207
901
4.03
37.97
3.7
3.0
—
—
—
0
0
42
9
52.57
35.56
4.8
1.4
—
—
—
0
0
117
354
4.41
35.55
3.8
1.7
—
—
—
0
0
125
399
4.26
35.31
4.2
1.8
—
—
—
0
0
119
398
3.96
31.03
2.8
2.7
2.5
1.1
e6/l
0.50
59
203
31
29
11.60
29.05
2.1
1.7
—
—
—
0
0
121
429
3.73
28.70
2.9
2.6
0.9
0.9
e6/l
0.06
61
233
355
2885
12.92
23.80
8.7
4.0
6.0
6.0
mmol/l
0.03
355
2699
44
84
5.82
22.63
2.4
1.6
—
—
—
0
0
46
104
4.92
19.55
1.5
1.6
1.2
1.6
g/l
1.80
41
95
357
3081
12.49
17.18
8.9
4.1
1.3
1.3
mmol/l
2.86
357
2907
347
2757
7.24
16.92
8.6
5.1
35.9
39.6
mmol/mol
14.90
347
2630
65
214
3.48
16.54
2.3
2.3
78.2
70.6
ml/min/173m2
1.00
37
91
331
2559
4.43
16.25
28.8
15.0
13.3
13.5
%
2.24
331
2514
356
3084
10.31
15.97
9.0
4.2
4.5
4.7
mmol/l
4.45
356
2922
357
3111
11.68
15.77
9.1
4.4
2.8
2.9
mmol/l
0.68
357
2939
28
49
6.11
15.64
4.0
3.5
2.9
4.3
e9/l
3.73
28
49
18
19
9.92
15.34
6.6
3.1
43.6
33.6
mu/l
0.46
18
19
28
51
5.87
15.02
4.0
3.9
49.1
54.9
%
1.73
28
51
27
49
5.87
14.53
1.2
1.4
—
—
—
0
0
27
49
5.87
14.53
1.2
1.4
—
—
—
0
0
106
496
2.61
14.25
1.4
1.4
17.3
20.1
nmol/l
1.85
100
431
37
92
4.37
13.91
1.2
1.7
0.0
0.1
iu/ml
0.68
19
17
17
20
8.87
13.35
1.1
1.0
—
—
—
0
0
346
2858
5.77
13.33
22.7
11.1
88.0
88.7
ml/min/173m2
0.25
333
2356
40
114
3.82
12.51
1.4
1.4
—
—
—
0
0
72
300
2.75
12.02
3.5
4.1
221.1
248.5
u/l
0.78
72
286
19
30
6.63
11.66
5.2
3.4
—
—
—
0
0
348
2988
5.26
10.42
16.4
12.6
21.1
23.1
mg/l
0.58
280
2344
13
7
19.20
8.99
1.6
1.0
—
—
iu/ml
—
0
0
30
90
3.54
8.69
2.9
3.1
—
—
—
0
0
13
8
16.78
8.61
1.2
1.0
—
—
—
0
0
44
176
2.71
7.85
1.5
1.5
—
—
—
0
0
58
267
2.40
7.74
1.7
1.7
—
—
—
0
0
94
532
2.04
7.52
2.2
2.0
2.6
3.1
mg/l
1.20
83
464
57
277
2.26
6.69
1.8
1.8
—
—
—
0
0
12
454
0.24
6.52
1.2
1.8
—
—
—
0
0
46
208
2.39
6.37
1.8
1.4
—
—
—
0
0
23
76
3.16
5.75
1.2
1.7
—
—
—
0
0
31
127
2.58
5.28
1.5
1.6
—
—
—
0
0
33
143
2.44
5.02
1.8
1.2
—
—
—
0
0
10
20
5.11
4.80
1.8
3.0
—
—
—
0
0
151
1108
1.62
4.72
6.3
7.1
1.2
1.2
mmol/l
0.21
144
1033
131
933
1.63
4.59
1.9
1.8
98.8
95.3
pmol/l
0.46
80
517
65
386
1.83
4.36
1.8
1.9
—
—
—
0
0
329
2979
2.15
4.35
28.4
12.5
42.1
42.1
%
0.00
292
2449
58
337
1.86
4.16
2.3
3.0
8.8
8.5
umol/l
0.05
50
296
16
52
3.17
4.13
2.3
1.7
—
—
—
0
0
46
250
1.96
4.03
3.0
3.7
0.2
2.0
mmol/l
1.43
34
203
32
154
2.18
3.86
2.1
5.4
74.6
95.6
ng/l
1.02
32
148
6
5
12.17
3.77
3.5
1.6
—
—
—
0
0
110
790
1.56
3.58
3.6
4.2
11.5
9.9
mg/mmol
0.18
77
535
14
47
3.06
3.45
2.3
1.6
—
—
—
0
0
155
1216
1.48
3.28
6.6
7.8
1.2
1.2
mmol/l
0.04
136
1043
16
60
2.74
3.27
1.0
1.2
—
—
—
0
0
7
11
6.46
3.20
1.0
1.0
31.1
27.8
umol/l
—
7
11
130
992
1.48
3.12
2.1
2.3
72.6
71.5
nmol/l
0.15
124
912
19
81
2.42
3.04
1.2
1.1
—
—
—
0
0
57
363
1.68
3.00
2.1
1.7
952.7
1182.6
nmol/l
1.39
51
295
13
312
0.39
2.91
5.5
6.8
—
—
—
0
0
6
9
6.76
2.88
1.2
1.0
—
—
—
0
0
6
9
6.76
2.88
1.2
1.0
—
—
—
0
0
9
23
3.99
2.79
1.7
3.1
—
—
—
0
0
44
266
1.74
2.79
2.9
3.2
—
—
—
0
0
27
141
1.99
2.68
1.3
1.7
2.1
4.5
mg/l
1.50
27
101
71
496
1.54
2.55
3.1
3.4
29.9
560.7
ng/l
1.92
52
362
18
83
2.23
2.45
1.2
1.1
—
—
—
0
0
95
1224
0.70
2.37
2.7
3.3
25.5
21.3
%
0.92
34
443
209
2366
0.72
2.34
4.7
3.2
67.6
53.7
u/l
1.09
196
2254
80
1055
0.69
2.25
2.7
3.1
23.0
40.5
ng/l
1.00
42
662
10
37
2.75
2.12
1.3
1.4
—
—
—
0
0
15
69
2.22
2.07
1.5
2.1
70.7
131.3
mg/l
0.28
15
53
9
32
2.86
2.01
1.1
1.5
—
—
—
0
0
9
32
2.86
2.01
1.1
1.5
—
—
—
0
0
9
32
2.86
2.01
1.1
1.5
—
—
—
0
0
128
1537
0.74
1.97
3.4
3.6
2.2
1.8
ug/l
0.29
119
1424
8
28
2.90
1.87
1.0
1.1
—
—
—
0
0
78
592
1.40
1.84
2.0
2.2
1.7
1.5
%
1.16
64
529
11
47
2.38
1.79
1.5
1.4
—
—
—
0
0
6
18
3.37
1.75
1.0
1.2
—
—
—
0
0
7
24
2.95
1.73
1.1
1.0
—
—
—
0
0
7
24
2.95
1.73
3.1
2.5
—
—
—
0
0
7
24
2.95
1.73
1.1
1.0
—
—
—
0
0
14
68
2.10
1.72
1.2
2.0
—
1.2
—
0
10
59
785
0.70
1.70
2.2
2.5
338.5
3697.5
umol/l
1.75
53
714
14
69
2.07
1.67
1.4
2.1
59.9
31.1
mg/l
1.76
14
53
133
1112
1.31
1.67
2.6
2.7
241.2
164.6
ug/l
0.55
126
1055
11
49
2.28
1.65
1.4
1.5
—
—
—
0
0
11
49
2.28
1.65
1.4
1.5
—
—
—
0
0
11
49
2.28
1.65
1.5
1.5
—
—
—
0
0
11
49
2.28
1.65
1.4
1.5
—
—
—
0
0
98
786
1.34
1.64
5.1
3.6
2.4
2.3
mmol/l
0.29
83
711
8
32
2.53
1.60
1.1
1.5
—
—
—
0
0
7
26
2.72
1.59
1.1
1.2
—
—
—
0
0
11
50
2.24
1.58
1.5
1.6
—
—
—
0
0
8
33
2.46
1.54
1.1
1.5
—
—
—
0
0
8
33
2.46
1.54
1.1
1.5
—
—
—
0
0
5
125
0.39
1.53
3.0
3.6
25.8
25.1
mmol/l
—
5
120
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
5
16
3.15
1.44
1.0
1.1
675.6
279.1
iu/ml
—
5
16
79
628
1.33
1.40
1.3
1.2
2.4
1.2
u/ml
—
8
199
13
68
1.95
1.35
2.5
1.4
31.1
7.5
e6/l
—
8
51
5
18
2.80
1.29
1.0
1.3
—
—
—
0
0
61
476
1.34
1.23
3.0
3.8
0.8
0.8
mmol/l
0.11
53
458
6
26
2.33
1.19
1.3
1.6
—
—
—
0
0
8
154
0.51
1.17
2.0
1.6
—
—
—
0
0
221
2025
1.23
1.16
2.8
3.4
13.7
14.6
pmol/l
6.77
207
1881
15
88
1.74
1.13
1.0
1.1
—
—
—
0
0
8
40
2.02
1.12
1.0
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
13
73
1.81
1.12
2.3
3.8
0.6
0.3
u/ml
—
5
37
14
81
1.76
1.10
1.1
1.2
—
—
—
0
0
11
59
1.89
1.08
1.3
1.5
—
—
—
0
0
51
646
0.75
1.07
2.6
3.1
929.4
774.6
ng/l
0.23
46
521
79
652
1.27
1.06
1.9
1.8
2.9
1.1
mg/l
0.41
59
505
5
22
2.29
1.03
1.0
1.6
3.1
4.1
mg/l
—
5
22
5
22
2.29
1.03
1.2
1.0
—
—
—
0
0
9
47
1.94
1.03
2.1
1.7
—
—
—
0
0
13
76
1.74
1.00
1.1
1.2
239.2
230.5
u/ml
—
6
51
76
632
1.26
0.97
2.4
2.3
—
—
—
0
0
315
3027
1.31
0.96
17.2
14.0
3.9
4.0
mmol/l
2.40
307
2962
11
62
1.80
0.95
1.0
1.2
—
—
—
0
0
91
1057
0.81
0.93
5.4
2.8
—
—
—
0
0
6
32
1.89
0.82
1.2
1.4
—
—
—
0
0
5
97
0.51
0.79
1.0
1.1
—
3.4
—
0
13
5
25
2.01
0.73
1.0
1.1
—
—
—
0
0
7
40
1.76
0.71
1.0
1.2
—
—
—
0
0
112
1245
0.85
0.69
3.5
3.9
—
—
—
0
0
7
42
1.68
0.68
1.0
1.1
—
—
—
0
0
311
3013
1.23
0.66
16.1
13.9
138.9
139.6
mmol/l
6.82
305
2949
9
137
0.65
0.62
1.8
1.5
261.7
265.5
mu/l
—
9
129
5
30
1.68
0.61
1.2
1.4
—
—
—
0
0
5
30
1.68
0.61
1.0
2.2
—
—
—
0
0
6
35
1.73
0.58
1.7
1.1
—
—
—
0
0
6
35
1.73
0.58
1.0
1.1
—
—
—
0
0
27
212
1.30
0.57
2.6
2.4
—
22.2
—
0
17
67
584
1.18
0.56
1.5
1.5
—
—
—
0
0
13
90
1.46
0.56
1.5
1.6
—
—
—
0
0
232
2211
1.14
0.54
3.3
3.1
—
—
—
0
0
9
62
1.46
0.53
1.0
1.3
—
—
—
0
0
9
63
1.44
0.52
1.0
1.2
—
62.8
—
0
6
6
99
0.60
0.52
4.2
3.6
29.8
138.0
u/ml
—
6
82
22
171
1.31
0.51
1.1
1.2
136.2
119.3
iu/ml
—
5
62
83
921
0.87
0.49
2.2
2.4
0.7
0.7
ug/l
0.10
61
481
10
68
1.48
0.47
1.2
1.4
—
—
—
0
0
11
77
1.44
0.46
1.0
1.2
—
13.7
—
0
7
7
51
1.38
0.44
1.4
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
27.0
—
0
9
0
16
0.00
0.41
0.0
1.0
—
647.2
—
0
9
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
40
462
0.85
0.40
1.4
1.3
29.8
31.5
iu/ml
0.03
11
146
46
401
1.17
0.40
2.9
3.3
2.4
2.4
mmol/l
0.06
33
353
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
1.1
—
0
6
75
679
1.13
0.40
5.9
3.1
0.0
0.0
estimate
0.50
41
233
5
35
1.43
0.39
1.0
2.0
—
—
—
0
0
0
19
0.00
0.39
0.0
2.8
—
—
—
0
0
262
2542
1.11
0.37
4.0
3.9
1.9
1.8
mu/l
0.13
251
2377
37
425
0.86
0.36
1.4
1.2
5.6
8.1
u/ml
—
7
181
6
44
1.37
0.34
1.3
1.8
—
—
—
0
0
10
74
1.36
0.32
1.1
1.9
—
—
—
0
0
7
56
1.25
0.29
1.1
1.9
—
—
—
0
0
12
95
1.27
0.26
1.2
1.3
—
—
—
0
0
5
40
1.25
0.22
1.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
18.8
—
0
10
0
10
0.00
0.21
0.0
1.1
—
11.0
—
0
10
0
10
0.00
0.21
0.0
3.6
—
—
—
0
0
15
126
1.20
0.21
2.3
2.7
0.0
0.1
e6/l
2.98
15
120
0
13
0.00
0.21
0.0
1.8
—
69.2
—
0
13
0
14
0.00
0.20
0.0
3.8
—
80.0
—
0
14
6
52
1.16
0.19
1.0
1.1
—
—
—
0
0
7
61
1.15
0.17
1.1
1.1
—
—
—
0
0
7
62
1.13
0.17
1.0
1.7
—
—
—
0
0
10
117
0.85
0.13
1.2
1.4
13.1
19.0
iu/l
—
5
95
48
456
1.06
0.11
1.6
1.7
450.1
54657289.5
pmol/l
0.80
43
408
11
96
1.15
0.10
1.1
2.0
—
—
—
0
0
32
302
1.07
0.09
14.5
10.3
-0.9
1.0
mmol/l
1.21
22
247
6
57
1.05
0.08
1.5
1.2
102.0
116.9
%
—
6
52
19
176
1.08
0.07
1.9
3.2
0.2
1.6
mmol/l
—
9
131
6
75
0.80
0.07
1.3
1.8
—
—
—
0
0
20
186
1.08
0.07
2.0
3.1
4.7
5.2
kpa
2.37
20
175
8
76
1.05
0.07
1.1
1.8
—
—
—
0
0
9
88
1.02
0.07
1.6
1.8
—
—
—
0
0
20
187
1.07
0.06
1.8
2.0
248.9
229.3
pmol/l
0.43
20
177
10
93
1.08
0.02
1.6
2.0
—
—
—
0
0
16
155
1.03
0.00
1.4
1.4
—
—
—
0
0
14
144
0.97
0.00
1.1
1.0
—
—
—
0
0
5
55
0.91
0.00
1.0
1.0
—
1.5
—
0
26
0
9
0.00
0.00
0.0
1.1
—
1.3
—
0
9
6
60
1.00
0.00
1.5
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
5
53
0.94
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
10.0
—
0
5
0
6
0.00
0.00
0.0
3.0
—
51.6
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint AB1_HIV_NOS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_HIV_NOS | 3.161 [2.63, 3.81] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 201 out of 1214 males with AB1_HIV_NOS died.
Mortality risk
Mortality risk for people of age
years, who have AB1_HIV_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.477% |
| 5 | No data | 3.193% |
| 10 | No data | 8.646% |
| 15 | No data | 14.951% |
| 20 | No data | 24.987% |
Relationships between endpoints
↥Index endpoint: AB1_HIV_NOS – Unspecified human immunodeficiency virus [HIV] disease
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data