epiglottitis: Inflammation of the epiglottis.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
598 |
4. Check minimum number of eventsNone |
598 |
5. Include endpointsNone |
598 |
6. Filter based on genotype QC (FinnGen only) |
576 |
Control definitions (FinnGen only)
- Control exclude
- J10_UPPERINFEC
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- J05
- Name in latin
- Epiglottitis acuta
Similar endpoints
↥List of similar endpoints to
Acute epiglottitis
based on the number of shared cases.
Similar with more cases:
- Acute upper respiratory infections
- Diseases of the respiratory system
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5000 | 2010 | 2955 |
| Only index persons | 4606 | 1904 | 2702 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.06 | 0.08 |
| Only index persons | 0.09 | 0.07 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 41.89 | 40.32 | 42.82 |
| Only index persons | 41.03 | 39.96 | 41.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 576 | 272 | 304 |
| Unadjusted period prevalence (%) | 0.12 | 0.10 | 0.14 |
| Median age at first event (years) | 45.91 | 39.75 | 51.42 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 598
- Matched controls
- 5980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J05.1
ICD-10 Finland
Acute epiglottitis
+∞
307.7
497
*
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
19.4
103.2
84
50
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
10.2
75.8
92
105
UDH02
NOMESCO Finland
Rhinopharyngoscopy
8.2
74.6
110
160
4643A
ICD-9 Finland
Acute laryngitis and tracheitis, Acute epiglottitis
+∞
64.8
61
*
J36
ICD-10 Finland
Peritonsillar abscess
11.5
64.4
70
68
UDQ12
NOMESCO Finland
Flexible laryngoscopy
7.2
57.8
94
151
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
17.7
51.8
43
26
46404
ICD-8 Finland
Acute laryngitis and tracheitis, Epiglottidis acuta
+∞
46.5
44
*
J04.0
ICD-10 Finland
Acute laryngitis
9.2
39.6
50
59
J05.0
ICD-10 Finland
Acute obstructive laryngitis [croup]
+∞
33.7
32
*
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
+∞
30.5
29
*
R07.0
ICD-10 Finland
Pain in throat
4.8
29.6
72
166
R21
ICPC
Throat symptom/complaint
3.0
29.4
172
715
EMB10
NOMESCO Finland
Tonsillectomy
4.8
26.1
62
140
J03.0
ICD-10 Finland
Streptococcal tonsillitis
7.3
25.3
38
55
J01FF01
ATC
clindamycin; systemic
2.6
24.0
196
954
H02AB06
ATC
prednisolone; systemic
2.4
23.3
307
1847
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
21.7
298
1808
J01DB01
ATC
cefalexin; oral
3.3
21.1
526
4136
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
20.9
273
1617
GBB00
NOMESCO Finland
Tracheostomy
17.1
19.8
31
19
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
20.2
19.7
29
15
TDM10
NOMESCO Finland
Puncture of maxillary antrum
8.2
19.3
26
33
ENA32
NOMESCO Finland
Incision of deep pharyngeal infection
54.3
18.1
21
*
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
15.9
233
1406
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.0
15.4
296
1964
4659X
ICD-9 Finland
Acute upper respiratory infections of multiple or unspecified sites, Unspecified site
+∞
14.6
14
*
J39.0
ICD-10 Finland
Retropharyngeal and parapharyngeal abscess
37.0
14.5
18
5
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
14.2
167
922
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
+∞
13.6
13
*
A02BC02
ATC
pantoprazole; systemic
2.0
13.5
392
2940
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
13.4
126
635
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.3
13.2
113
547
J46
ICD-10 Finland
Status asthmaticus
6.3
13.0
22
36
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
13.0
317
2236
WX707
NOMESCO Finland
Fiberoscopic intubation
51.2
12.9
15
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
12.8
261
1736
R06.0
ICD-10 Finland
Dyspnoea
2.1
12.6
153
849
J01DA01
ATC
[U] cefalexin
1.9
12.6
372
2778
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
12.6
101
475
N02AX02
ATC
tramadol; systemic, rectal
1.9
12.6
258
1716
ZXE00
NOMESCO Finland
One hour or less
1.9
12.3
236
1534
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.7
12.0
28
62
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
11.7
136
742
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.1
11.5
51
177
ZXD05
NOMESCO Finland
Urgent procedure
1.9
11.2
193
1205
UJC01
NOMESCO Finland
Scopy of lower throat
9.4
10.6
21
23
M79.6
ICD-10 Finland
Pain in limb
1.8
10.6
236
1589
J38.4
ICD-10 Finland
Oedema of larynx
16.4
10.4
16
10
J01FA09
ATC
clarithromycin; systemic
1.9
10.3
179
1115
R03AC02
ATC
salbutamol; inhalant
1.7
10.1
315
2325
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
10.1
173
1070
JDB10
NOMESCO Finland
Percutaneous gastrostomy
11.6
10.1
18
16
ZXA10
NOMESCO Finland
Bilateral
2.1
9.8
103
537
N02BE01
ATC
paracetamol; systemic, rectal
2.2
9.7
518
4479
J01AA02
ATC
doxycycline; systemic
1.8
9.4
437
3581
J01FA15
ATC
telithromycin; oral
2.4
9.3
64
279
P01AB01
ATC
metronidazole; oral, rectal
1.7
9.1
228
1570
R52.9
ICD-10 Finland
Pain, unspecified
2.4
9.1
64
283
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
8.8
67
306
J39.1
ICD-10 Finland
Other abscess of pharynx
50.7
8.7
10
*
A02BC05
ATC
esomeprazole; systemic
1.7
8.7
224
1553
R05
ICPC
Cough
1.9
8.5
127
748
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.9
8.4
40
145
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
+∞
8.3
8
*
J01CE02
ATC
phenoxymethylpenicillin; oral
1.7
8.2
406
3314
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
8.1
239
1707
L28
ICPC
Limited function/disability (L)
2.1
8.1
85
442
R03AK07
ATC
formoterol and budesonide; inhalant
1.9
8.1
124
737
UDC00
NOMESCO Finland
Ear microscopy
2.6
8.0
47
190
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
8.0
196
1334
J37.0
ICD-10 Finland
Chronic laryngitis
3.8
8.0
24
65
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
8.0
83
431
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.0
7.9
22
56
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
7.9
119
701
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
7.9
200
1371
SPAT1263
SPAT
Sampling
1.7
7.9
223
1573
SPAT1310
SPAT
Counselling related to known health issue
1.7
7.7
173
1147
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
8.2
7.6
16
20
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.4
7.6
27
82
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
7.8
7.4
16
21
K11.2
ICD-10 Finland
Sialoadenitis
3.8
7.4
22
59
J01.4
ICD-10 Finland
Acute pansinusitis
+∞
7.3
7
*
4630A
ICD-9 Finland
Acute tonsillitis[TONSILLITIS ACUTA]
+∞
7.3
7
*
R50.9
ICD-10 Finland
Fever, unspecified
2.0
7.3
83
445
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.3
7.3
53
238
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
7.3
74
381
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.3
7.2
56
258
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
7.2
203
1425
J01DA06
ATC
[U] cefuroxime
2.0
7.2
87
476
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.3
7.2
27
85
J02
ICD-10 Finland
Acute pharyngitis
3.1
7.1
29
96
N03AX16
ATC
[U] pregabalin
1.8
7.0
121
742
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
7.0
60
288
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
7.0
113
679
J01MA14
ATC
moxifloxacin; systemic
2.4
7.0
49
216
R13
ICD-10 Finland
Dysphagia
2.5
6.9
43
179
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
7.7
6.9
15
20
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
6.8
125
780
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
6.8
104
614
J01MA02
ATC
ciprofloxacin; systemic
1.6
6.8
205
1459
SPAT1360
SPAT
Extensive global examination
2.7
6.7
37
145
J20
ICD-10 Finland
Acute bronchitis
2.2
6.7
55
260
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.9
6.7
31
111
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
6.7
93
534
M54.5
ICD-10 Finland
Low back pain
1.6
6.7
197
1395
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
6.6
107
643
A03
ICPC
Fever
1.9
6.6
96
558
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.0
6.6
69
359
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
6.5
54
256
L04AX01
ATC
azathioprine; systemic
3.2
6.5
25
80
N06AX16
ATC
venlafaxine; oral
1.9
6.5
84
470
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.7
6.4
153
1026
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
6.4
142
934
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
6.7
6.4
15
23
M23.8
ICD-10 Finland
Other internal derangements of knee
2.9
6.3
28
98
46309
ICD-8 Finland
Acute tonsillitis, Unspecified
+∞
6.3
6
*
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
2.7
6.3
32
121
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
6.2
53
254
H65.3
ICD-10 Finland
Chronic mucoid otitis media
5.4
6.2
17
32
R03BA02
ATC
budesonide; inhalant
1.8
6.2
97
578
L50.9
ICD-10 Finland
Urticaria, unspecified
3.1
6.1
25
83
J01
ICD-10 Finland
Acute sinusitis
2.9
6.1
29
105
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
6.1
405
3418
R01AD12
ATC
fluticasone furoate; nasal
1.6
6.1
169
1173
X58
ICD-10 Finland
Exposure to other specified factors
1.9
6.1
86
495
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
6.1
75
413
K04.08
ICD-10 Finland
Other specified pulpit
2.2
6.1
50
237
4451
FHL
Guitar cutting
3.4
6.0
21
63
N06AX11
ATC
mirtazapine; oral
1.6
6.0
180
1273
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
139
582
2.81
22.89
2.1
1.7
—
—
—
0
0
340
2184
2.29
21.54
7.0
5.8
26.46
28.27
%
2.34
325
2075
329
2158
2.17
18.88
6.6
5.6
58.73
56.76
%
2.28
314
2045
99
398
2.78
17.30
1.6
1.6
—
—
—
0
0
99
406
2.72
16.62
1.7
1.6
—
—
—
0
0
168
898
2.21
15.68
1.8
1.4
—
—
—
0
0
36
83
4.55
14.70
1.9
1.4
—
—
—
0
0
363
2614
1.99
14.61
10.3
8.9
4.26
4.07
e9/l
0.68
319
2291
27
57
4.91
12.24
2.0
1.4
—
—
—
0
0
28
61
4.77
12.24
4.8
2.7
58.71
58.18
%
0.07
28
61
350
2585
1.85
12.01
6.3
4.5
6.96
6.65
mmol/l
1.46
332
2407
27
59
4.75
11.76
4.8
2.5
4.00
4.57
e9/l
0.67
27
59
312
2238
1.82
11.64
6.2
6.5
9.99
11.73
umol/l
3.93
298
2142
32
86
3.87
10.72
1.8
1.4
—
—
—
0
0
26
60
4.48
10.61
1.8
1.5
—
—
—
0
0
26
60
4.48
10.61
1.8
1.5
—
—
—
0
0
144
837
1.95
10.21
3.1
2.4
5.33
5.70
e6/l
0.11
138
759
541
4752
2.45
9.86
19.9
11.9
30.05
23.45
mg/l
3.46
489
3643
166
1029
1.85
9.60
2.4
1.9
3.04
2.89
mg/l
0.27
137
876
60
252
2.53
9.48
1.4
1.3
—
—
—
0
0
34
104
3.41
9.45
2.2
1.7
—
—
—
0
0
196
1288
1.78
9.30
4.1
2.9
53.76
116.63
e6/l
0.49
160
983
175
1121
1.79
9.01
4.4
3.7
91.34
91.72
%
0.08
170
1099
423
3465
1.75
8.77
9.0
7.3
75.40
76.67
u/l
0.29
409
3280
178
1165
1.75
8.43
4.2
2.8
0.59
0.47
e6/l
0.12
142
866
59
262
2.39
8.27
1.6
1.6
—
—
—
0
0
218
1520
1.68
8.15
4.2
2.9
—
—
—
0
0
247
1793
1.64
7.82
8.3
5.8
1.20
1.21
mmol/l
1.20
229
1639
245
1784
1.63
7.61
5.9
5.1
35.35
36.16
g/l
1.56
230
1671
163
1068
1.72
7.58
2.6
3.0
1426.82
1226.84
ng/l
0.21
137
912
20
50
4.10
7.40
1.5
1.3
—
—
—
0
0
261
1941
1.61
7.38
15.3
11.6
1.28
1.23
inr
0.45
110
553
50
219
2.40
7.23
1.8
1.5
—
—
—
0
0
483
4196
1.79
7.19
21.8
14.5
14.59
14.65
%
0.09
477
4139
267
2006
1.60
7.17
9.3
6.7
1.20
1.21
mmol/l
1.00
214
1726
76
400
2.03
7.02
1.6
1.9
347.03
373.66
nmol/l
0.55
70
371
394
3263
1.61
6.86
3.5
3.1
—
—
—
0
0
401
3341
1.61
6.76
4.9
3.7
14.16
10.40
mm/h
4.49
375
3123
94
541
1.88
6.69
3.1
2.4
23.58
24.18
%
0.14
80
475
17
29
6.00
6.65
2.2
1.7
—
—
—
0
0
17
29
6.00
6.65
2.2
1.7
—
—
—
0
0
17
29
6.00
6.65
2.2
1.7
—
—
—
0
0
109
662
1.79
6.52
4.2
3.6
0.79
0.83
mmol/l
2.37
102
630
85
478
1.91
6.49
9.1
7.6
1.26
1.07
mmol/l
0.17
69
383
169
1163
1.63
6.38
3.3
2.5
8029.64
4353.40
umol/l
0.37
143
1044
9
5
18.24
6.28
1.0
1.0
95.67
93.40
%
—
9
5
191
1360
1.59
6.24
2.8
2.6
52.51
61.43
u/l
1.46
181
1274
19
52
3.74
6.24
1.6
1.3
—
—
—
0
0
90
523
1.85
6.20
2.1
3.1
5.79
8.06
umol/l
1.08
75
468
106
648
1.77
6.19
2.9
2.3
12.98
14.20
umol/l
0.92
96
613
73
400
1.94
6.01
4.0
3.0
—
—
—
0
0
188
1347
1.58
5.94
3.4
3.2
8.19
8.13
mmol/l
0.06
160
1160
22
70
3.22
5.79
1.7
1.3
—
—
—
0
0
530
4815
1.89
5.78
21.4
13.4
139.28
139.66
mmol/l
3.15
521
4710
88
519
1.82
5.78
10.7
6.3
104.33
104.13
mmol/l
0.12
88
519
195
1417
1.56
5.76
3.3
3.3
2.33
2.35
mmol/l
1.10
173
1294
144
975
1.63
5.73
2.0
1.7
2.18
1.14
mg/l
0.56
108
758
17
37
4.70
5.52
1.6
1.3
—
—
—
0
0
120
784
1.66
5.48
3.7
3.4
178.74
566.59
ng/l
1.29
82
594
530
4833
1.85
5.45
21.5
13.5
3.96
3.97
mmol/l
0.65
521
4717
65
355
1.93
5.41
10.3
6.4
1.16
1.32
mmol/l
1.22
65
345
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
27
101
2.75
5.41
3.1
2.0
0.26
0.36
u/ml
0.76
15
50
64
350
1.93
5.31
5.8
3.4
1.86
1.95
mmol/l
0.08
57
280
15
30
5.10
5.28
1.1
1.0
—
—
—
0
0
19
59
3.29
5.21
1.7
1.3
—
—
—
0
0
11
15
7.45
5.16
2.8
1.7
—
—
—
0
0
11
15
7.45
5.16
2.8
1.7
—
—
—
0
0
95
592
1.72
5.16
3.1
2.3
2.28
2.34
g/l
0.41
86
558
162
1159
1.55
5.03
3.9
3.3
0.00
0.00
estimate
-0.00
76
399
70
402
1.84
5.00
10.6
8.4
121.60
124.31
g/l
0.53
70
392
86
531
1.72
4.82
8.0
5.9
1.06
1.04
mmol/l
0.21
80
499
16
47
3.47
4.77
1.3
1.9
32.69
33.34
pg
0.20
16
47
405
3504
1.48
4.75
4.3
3.7
14.52
14.61
pmol/l
0.28
368
3217
23
87
2.71
4.54
2.0
1.4
—
—
—
0
0
20
71
2.88
4.43
1.7
1.5
—
—
—
0
0
277
2252
1.43
4.40
3.7
3.1
0.00
0.00
estimate
-0.00
75
387
113
768
1.58
4.35
1.4
1.3
23.78
32.13
iu/ml
0.43
33
249
15
45
3.39
4.35
1.1
1.5
—
—
—
0
0
15
45
3.39
4.35
1.1
1.5
—
—
—
0
0
20
73
2.80
4.22
4.5
2.3
15.40
15.92
%
—
9
41
273
2226
1.42
4.21
5.0
4.2
0.00
0.00
estimate
-0.00
82
412
28
122
2.36
4.17
2.8
3.1
—
—
—
0
0
273
2229
1.41
4.16
3.7
3.1
0.00
0.00
estimate
0.50
82
437
32
148
2.23
4.16
3.6
1.8
—
—
—
0
0
259
2098
1.41
4.12
3.4
2.6
138.52
120.10
ug/l
0.45
237
1954
572
5430
2.23
4.06
27.8
17.5
255.99
249.65
e9/l
1.25
559
5312
549
5141
1.83
4.05
12.6
9.3
27.37
27.69
u/l
0.15
534
4995
108
742
1.56
3.95
3.7
2.8
2.44
2.43
mmol/l
0.36
88
660
14
43
3.31
3.93
1.4
1.2
—
—
—
0
0
572
5437
2.20
3.93
27.8
17.5
4.52
4.57
e12/l
1.37
557
5310
11
23
4.85
3.88
1.9
1.2
—
—
—
0
0
18
65
2.82
3.88
1.3
1.2
—
—
—
0
0
18
65
2.82
3.88
1.3
1.2
—
—
—
0
0
572
5440
2.18
3.87
28.0
17.6
135.18
137.83
g/l
4.04
564
5381
168
1271
1.45
3.85
4.6
3.9
12.36
9.15
mg/mmol
0.28
115
822
571
5428
2.15
3.85
28.2
17.6
40.17
40.84
%
1.78
543
5122
264
2179
1.38
3.62
3.0
2.5
—
—
—
0
0
15
51
2.99
3.59
1.9
1.3
—
—
—
0
0
219
1755
1.39
3.59
2.4
2.2
75.08
74.86
nmol/l
0.04
195
1601
29
138
2.16
3.55
3.1
1.7
—
—
—
0
0
9
17
5.36
3.52
2.1
1.2
—
—
—
0
0
9
17
5.36
3.52
2.1
1.2
—
—
—
0
0
202
1602
1.39
3.51
3.3
3.5
29.81
31.79
u/l
0.54
190
1537
99
685
1.53
3.50
3.9
2.6
1.51
1.77
e6/l
0.22
52
366
472
4303
1.46
3.49
5.0
4.3
1.87
1.85
mu/l
0.21
434
3994
201
1596
1.39
3.45
3.9
3.2
36.59
43.80
ng/l
0.29
128
1029
7
10
7.07
3.37
3.7
5.8
—
—
—
0
0
13
43
3.07
3.27
2.2
1.5
—
—
—
0
0
16
60
2.71
3.25
1.3
1.2
—
—
—
0
0
120
879
1.46
3.22
1.6
1.6
436.58
12814158.47
pmol/l
0.79
96
757
10
24
4.22
3.20
2.0
2.0
—
—
—
0
0
100
709
1.49
3.15
4.1
2.5
0.54
0.94
e6/l
1.34
54
391
100
711
1.49
3.11
1.9
1.6
1225.75
1169.03
nmol/l
0.22
68
551
489
4519
1.45
3.08
18.0
10.8
86.41
85.39
ml/min/173m2
0.47
427
3665
99
704
1.49
3.08
1.8
1.9
1.54
1.43
%
0.66
86
632
135
1021
1.42
3.04
1.3
1.2
2.62
1.80
u/ml
0.21
38
302
33
179
1.89
2.88
2.5
7.1
1.84
1.65
%
0.38
33
166
7
13
5.43
2.87
1.4
1.6
40.23
67.41
ug/l
—
7
13
7
13
5.43
2.87
3.1
1.6
—
—
—
0
0
7
13
5.43
2.87
3.1
1.6
—
—
—
0
0
7
13
5.43
2.87
3.1
1.6
—
—
—
0
0
6
9
6.72
2.87
1.0
1.2
—
—
—
0
0
25
124
2.06
2.80
1.4
1.2
—
24.79
—
0
7
203
1664
1.33
2.74
2.0
1.8
94.05
96.23
pmol/l
0.27
104
901
163
1293
1.36
2.73
2.5
2.0
140.64
269.88
u/l
1.50
154
1227
12
40
3.04
2.70
2.3
1.5
—
—
—
0
0
13
49
2.69
2.64
9.2
6.2
12.02
10.69
mg/l
0.42
13
43
22
107
2.10
2.60
9.8
3.9
107.51
31.65
mg/l
0.42
16
92
22
107
2.10
2.60
9.7
3.9
59.51
116.16
mg/l
0.47
16
91
62
414
1.56
2.59
2.4
2.4
33.35
34.47
u/l
0.09
52
351
25
128
1.99
2.59
1.6
1.4
265.24
279.28
ug/g
0.15
17
72
9
25
3.64
2.58
1.7
1.5
13.11
14.12
u/l
—
9
25
9
25
3.64
2.58
2.1
1.2
—
—
—
0
0
9
25
3.64
2.58
2.0
1.2
14.44
9.68
u/l
—
9
25
5
7
7.19
2.55
2.8
1.4
—
—
—
0
0
211
1754
1.31
2.55
3.9
3.1
—
—
—
0
0
13
50
2.64
2.54
1.2
1.1
—
—
—
0
0
11
37
3.01
2.50
2.0
1.2
99.55
79.68
umol/l
0.61
11
37
43
265
1.67
2.49
3.7
4.2
93.69
83.51
ng/l
0.26
36
246
32
182
1.80
2.44
3.2
2.4
0.69
0.66
%
0.11
32
182
40
243
1.69
2.44
3.6
3.6
0.99
1.83
mmol/l
0.82
27
181
6
12
5.04
2.40
1.2
1.6
116.33
84.25
nmol/24h
—
6
12
82
591
1.45
2.39
2.4
1.8
—
—
—
0
0
20
101
2.01
2.18
1.3
1.2
—
32.57
—
0
10
22
116
1.93
2.13
1.4
1.3
—
—
—
0
0
12
49
2.48
2.11
1.2
1.0
0.08
0.15
u/ml
—
5
13
89
667
1.39
2.11
2.4
1.9
—
—
—
0
0
372
3392
1.26
1.96
3.4
3.1
50.61
46.93
u/l
0.38
349
3227
26
150
1.77
1.94
3.5
1.7
—
—
—
0
0
51
351
1.50
1.90
2.7
2.3
71.80
70.90
ml/min/173m2
0.05
25
145
21
114
1.87
1.89
1.1
1.1
—
—
—
0
0
15
72
2.11
1.87
5.9
5.8
359.73
391.95
umol/l
0.51
15
66
8
28
2.88
1.86
1.0
1.1
—
—
—
0
0
37
239
1.58
1.83
1.1
1.1
—
—
—
0
0
463
4348
1.29
1.82
6.2
5.2
40.62
39.29
mmol/mol
1.77
425
4108
7
23
3.07
1.80
3.0
3.0
685.43
694.35
u/ml
—
7
23
147
1214
1.28
1.80
1.7
1.6
1.59
1.41
mmol/l
1.11
124
1050
132
1076
1.29
1.79
3.3
2.2
—
—
—
0
0
30
185
1.65
1.79
3.6
3.5
25.57
25.21
mmol/l
0.26
30
178
94
733
1.34
1.75
1.3
1.3
3.60
10.56
u/ml
1.51
32
298
117
943
1.30
1.73
1.6
1.5
18.45
20.79
nmol/l
1.40
106
828
5
13
3.87
1.72
1.2
1.0
—
—
—
0
0
11
48
2.32
1.71
1.4
1.4
341.09
410.74
pmol/l
0.25
11
43
502
4777
1.32
1.70
4.3
4.1
4.62
4.70
mmol/l
0.93
465
4507
6
19
3.18
1.66
2.7
2.0
—
—
—
0
0
8
31
2.60
1.66
2.6
1.3
—
—
—
0
0
10
41
2.46
1.65
1.0
1.0
—
—
—
0
0
10
41
2.46
1.65
1.1
1.2
46.20
48.49
u/l
—
10
36
40
271
1.51
1.63
8.1
7.4
24.93
24.54
mmol/l
0.40
40
257
22
128
1.75
1.62
1.7
2.5
10.31
11.96
mg/l
0.37
22
120
25
151
1.68
1.62
2.1
1.9
87.88
90.26
%
0.20
25
145
7
26
2.71
1.58
1.1
1.1
—
—
—
0
0
11
50
2.22
1.57
2.7
1.6
—
—
—
0
0
11
50
2.22
1.57
2.5
1.6
—
—
—
0
0
11
50
2.22
1.57
2.6
1.6
—
—
—
0
0
5
15
3.35
1.52
1.0
1.1
—
—
—
0
0
7
27
2.61
1.52
1.0
1.1
—
—
—
0
0
11
51
2.18
1.51
2.5
1.5
—
—
—
0
0
11
51
2.18
1.51
2.5
1.5
—
—
—
0
0
6
21
2.88
1.51
1.2
1.2
48.17
9.88
u/l
—
6
16
6
21
2.88
1.51
1.2
1.2
118.67
64.25
u/l
—
6
16
15
79
1.92
1.50
1.3
1.1
0.52
3.49
u/ml
—
10
39
5
16
3.14
1.44
1.6
1.3
—
—
—
0
0
9
39
2.33
1.43
3.3
3.6
—
—
—
0
0
18
103
1.77
1.42
1.3
1.3
—
—
—
0
0
18
103
1.77
1.42
1.2
1.3
—
—
—
0
0
482
4592
1.26
1.41
3.9
3.7
1.39
1.31
mmol/l
1.09
439
4291
16
89
1.82
1.38
2.4
1.4
—
—
—
0
0
28
185
1.54
1.31
1.8
2.1
1190.85
3650.51
u/l
1.31
11
82
497
4763
1.26
1.30
4.3
4.0
1.41
1.43
mmol/l
0.56
458
4468
6
24
2.51
1.30
1.2
1.5
—
100.00
—
0
5
6
24
2.51
1.30
1.0
1.1
1050.33
1307.12
miu/ml
—
6
24
8
34
2.37
1.29
1.1
1.2
—
70.00
—
0
6
10
49
2.06
1.22
2.7
1.6
—
—
—
0
0
6
26
2.32
1.19
1.0
1.2
243.33
143.99
iu/ml
—
6
26
505
4862
1.25
1.18
4.8
4.5
2.71
2.82
mmol/l
1.87
464
4560
38
275
1.41
1.16
1.3
1.3
26.33
25.65
iu/l
0.04
33
232
8
39
2.07
1.15
1.0
1.3
—
—
—
0
0
46
345
1.36
1.15
4.0
2.2
3.82
8.54
ug/l
3.10
38
308
21
135
1.58
1.13
2.7
2.4
3.73
3.72
g/l
0.02
21
130
5
21
2.39
1.09
2.2
2.2
—
—
—
0
0
5
21
2.39
1.09
2.2
2.2
—
—
—
0
0
15
91
1.67
1.01
1.7
1.5
121.40
114.00
u/ml
—
5
17
7
35
2.01
1.00
3.3
3.3
—
—
—
0
0
477
4589
1.19
0.98
4.6
4.1
6.19
5.88
mmol/l
3.23
425
4252
5
23
2.18
0.98
1.0
1.0
109.80
98.61
%
—
5
18
7
36
1.96
0.97
1.0
1.2
—
—
—
0
0
7
36
1.96
0.97
1.0
1.2
—
—
—
0
0
21
141
1.51
0.96
2.1
1.8
—
—
—
0
0
15
93
1.63
0.94
1.4
1.3
1195.11
867.56
e6/l
—
9
79
15
93
1.63
0.94
1.3
1.2
23.89
5.32
e6/l
—
9
75
7
37
1.90
0.94
1.0
1.2
—
—
—
0
0
7
37
1.90
0.94
1.0
1.2
—
—
—
0
0
7
37
1.90
0.94
1.0
1.2
—
—
—
0
0
6
28
2.15
0.91
1.5
1.3
32.56
36.71
nmol/l
—
6
22
15
94
1.61
0.91
1.3
1.2
—
—
—
0
0
11
63
1.76
0.90
1.2
1.4
—
—
—
0
0
8
42
1.92
0.89
4.5
2.8
—
—
—
0
0
6
30
2.01
0.87
1.5
1.8
—
—
—
0
0
46
573
0.79
0.82
1.5
1.8
—
—
—
0
0
14
89
1.59
0.82
1.4
1.2
313.13
270.95
u/ml
—
8
55
20
139
1.45
0.80
3.9
2.2
—
—
—
0
0
44
349
1.28
0.80
1.2
1.2
54.72
146.07
iu/ml
3.45
24
150
6
33
1.83
0.79
1.0
1.0
—
—
—
0
0
30
226
1.34
0.78
2.5
2.8
0.14
0.12
e6/l
0.09
30
216
6
34
1.77
0.76
1.2
1.1
—
—
—
0
0
45
363
1.26
0.73
2.5
1.8
—
—
—
0
0
23
168
1.38
0.72
1.1
1.3
—
—
—
0
0
9
59
1.53
0.68
2.1
2.2
—
—
—
0
0
7
42
1.67
0.68
1.3
1.2
—
—
—
0
0
17
120
1.43
0.65
3.3
2.2
97.57
64.58
ug/min
0.24
11
69
5
30
1.67
0.61
1.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
8
53
1.52
0.58
1.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
2.4
—
83.78
—
0
23
11
159
0.69
0.55
1.4
1.5
—
—
—
0
0
6
40
1.50
0.51
1.3
1.6
—
—
—
0
0
7
45
1.56
0.49
1.0
1.1
—
—
—
0
0
20
156
1.29
0.45
1.3
1.3
275.85
225.78
miu/ml
0.24
15
79
14
103
1.37
0.45
2.8
10.4
105.79
105.68
mmol/l
0.04
14
94
7
51
1.38
0.44
2.0
4.6
—
74.23
u/ml
—
0
15
5
31
1.62
0.43
1.4
1.5
0.60
1.01
u/field
—
5
21
5
31
1.62
0.43
1.0
1.2
—
—
—
0
0
5
32
1.57
0.42
1.4
1.4
—
—
—
0
0
16
206
0.77
0.42
2.4
2.6
22.00
39.02
u/ml
0.71
16
198
8
60
1.34
0.40
1.0
1.1
—
—
—
0
0
12
160
0.74
0.40
1.1
1.5
—
—
—
0
0
37
426
0.86
0.36
4.7
4.7
4.57
31.29
ug/l
0.82
31
355
12
156
0.76
0.35
1.1
1.4
—
—
—
0
0
57
511
1.13
0.34
8.9
6.3
—
—
—
0
0
33
284
1.17
0.34
2.7
1.8
—
—
—
0
0
12
155
0.77
0.33
1.1
1.4
—
—
—
0
0
46
518
0.88
0.33
4.2
4.2
31.70
30.66
%
0.31
30
365
183
1740
1.07
0.33
4.4
4.4
1.88
2.24
ug/l
0.58
162
1570
6
47
1.28
0.32
1.3
1.1
1.52
1.49
nmol/l
—
6
41
12
154
0.77
0.32
1.1
1.4
—
—
—
0
0
12
154
0.77
0.32
1.1
1.4
—
—
—
0
0
77
706
1.10
0.32
1.5
1.5
—
—
—
0
0
15
186
0.80
0.31
1.3
1.4
—
—
—
0
0
16
129
1.25
0.30
1.3
1.5
—
—
—
0
0
7
55
1.28
0.30
1.7
2.6
108.71
104.84
mmol/l
—
7
55
7
56
1.25
0.29
1.0
1.1
—
—
—
0
0
12
151
0.79
0.28
1.8
1.5
—
—
—
0
0
11
86
1.28
0.26
2.4
1.7
—
—
—
0
0
10
77
1.30
0.26
1.1
1.1
—
—
—
0
0
10
77
1.30
0.26
1.0
1.1
—
—
—
0
0
9
73
1.24
0.25
1.0
1.1
127.22
113.71
%
—
9
66
23
265
0.86
0.24
1.3
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
370.83
—
0
6
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
103
980
1.06
0.19
3.9
3.3
1.01
1.02
kg/l
0.60
14
139
11
90
1.23
0.19
1.3
1.8
—
—
—
0
0
7
59
1.19
0.18
1.1
1.5
2.03
2.08
ug/l
—
7
53
28
253
1.11
0.17
1.6
1.3
—
—
—
0
0
17
194
0.87
0.17
1.5
1.8
—
—
—
0
0
16
139
1.16
0.16
1.6
1.1
—
—
—
0
0
16
139
1.16
0.16
1.6
1.1
—
—
—
0
0
8
72
1.11
0.16
1.9
1.6
—
—
—
0
0
6
79
0.76
0.15
1.0
1.1
—
—
—
0
0
106
1022
1.05
0.13
2.5
2.7
0.70
0.76
ug/l
0.46
67
614
16
143
1.12
0.11
1.7
1.7
180.44
210.64
pmol/l
0.53
16
132
15
134
1.12
0.11
1.9
1.7
—
—
—
0
0
5
44
1.14
0.10
1.0
1.8
89.32
16.58
ug/l
—
5
44
13
121
1.08
0.03
2.5
1.7
5.49
4.55
iu/l
—
8
41
10
107
0.93
0.02
2.0
1.6
—
—
—
0
0
18
187
0.96
0.01
1.6
1.7
33.83
39.16
nmol/l
0.75
18
177
140
1394
1.01
0.00
3.6
3.8
20.85
21.31
%
0.13
62
590
12
125
0.96
0.00
1.8
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
6
67
0.89
-0.00
1.3
1.4
12.55
21.58
u/l
—
6
54
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
119.83
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
90
1.00
-0.00
1.2
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint J10_EPIGLOTTITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_EPIGLOTTITIS | 1.186 [0.94, 1.5] | 0.152 |
| Birth year | 0.993 [0.98, 1.0] | 0.127 |
During the follow-up period (1.1.1998 — 31.12.2019), 121 out of 1403 females with J10_EPIGLOTTITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_EPIGLOTTITIS | 1.459 [1.22, 1.74] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 282 out of 1993 males with J10_EPIGLOTTITIS died.
Mortality risk
Mortality risk for people of age
years, who have J10_EPIGLOTTITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.084% | 0.284% |
| 5 | 0.639% | 1.731% |
| 10 | 1.61% | 4.157% |
| 15 | 3.083% | 7.877% |
| 20 | 5.572% | 13.424% |
Relationships between endpoints
↥Index endpoint: J10_EPIGLOTTITIS – Acute epiglottitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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