epiglottitis: Inflammation of the epiglottis.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
576 |
4. Check minimum number of eventsNone |
576 |
5. Include endpointsNone |
576 |
6. Filter based on genotype QC (FinnGen only) |
576 |
Control definitions (FinnGen only)
- Control exclude
- J10_UPPERINFEC
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- J05
- Name in latin
- Epiglottitis acuta
Similar endpoints
↥List of similar endpoints to
Acute epiglottitis
based on the number of shared cases.
Similar with more cases:
- Acute upper respiratory infections
- Diseases of the respiratory system
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5000 | 2010 | 2955 |
| Only index persons | 4606 | 1904 | 2702 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.06 | 0.08 |
| Only index persons | 0.09 | 0.07 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 41.89 | 40.32 | 42.82 |
| Only index persons | 41.03 | 39.96 | 41.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 576 | 269 | 307 |
| Unadjusted period prevalence (%) | 0.11 | 0.09 | 0.14 |
| Median age at first event (years) | 45.68 | 39.55 | 51.05 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 518
- Matched controls
- 5178
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J05.1
ICD-10 Finland
Acute epiglottitis
15225.4
323.0
426
*
4643A
ICD-9 Finland
Acute laryngitis and tracheitis, Acute epiglottitis
+∞
54.1
51
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
9.9
46.7
99
121
46404
ICD-8 Finland
Acute laryngitis and tracheitis, Epiglottidis acuta
+∞
46.6
44
*
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
16.7
43.0
70
48
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
10.8
35.3
70
74
J36
ICD-10 Finland
Peritonsillar abscess
12.2
31.9
59
54
UDQ12
NOMESCO Finland
Flexible laryngoscopy
7.3
29.9
75
117
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
+∞
28.4
27
*
R21
ICPC
Throat symptom/complaint
3.4
24.7
143
529
J05.0
ICD-10 Finland
Acute obstructive laryngitis [croup]
251.1
23.8
24
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
15.5
23.8
39
27
J01DB01
ATC
cefalexin; oral
3.2
21.9
448
3466
J04.0
ICD-10 Finland
Acute laryngitis
10.3
21.2
42
44
H02AB06
ATC
prednisolone; systemic
2.4
19.6
250
1451
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.4
19.3
265
1594
R07.0
ICD-10 Finland
Pain in throat
5.9
19.1
55
103
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
16.7
223
1291
GBB00
NOMESCO Finland
Tracheostomy
18.7
16.6
25
14
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.3
16.4
224
1309
J03.0
ICD-10 Finland
Streptococcal tonsillitis
12.2
16.2
29
25
ENA32
NOMESCO Finland
Incision of deep pharyngeal infection
58.4
14.9
17
*
J39.0
ICD-10 Finland
Retropharyngeal and parapharyngeal abscess
154.2
14.5
15
*
M01AE03
ATC
ketoprofen; systemic, rectal
2.2
14.4
204
1192
J01FF01
ATC
clindamycin; systemic
2.3
14.1
157
820
EMB10
NOMESCO Finland
Tonsillectomy
4.4
13.7
50
122
N02AX02
ATC
tramadol; systemic, rectal
2.1
13.3
220
1363
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
13.1
153
812
A02BC02
ATC
pantoprazole; systemic
2.0
12.7
317
2294
4659X
ICD-9 Finland
Acute upper respiratory infections of multiple or unspecified sites, Unspecified site
+∞
12.5
12
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.5
11.6
96
427
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
+∞
11.5
11
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
11.1
142
778
J01DA01
ATC
[U] cefalexin; systemic
1.9
10.7
323
2429
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
10.1
207
1352
J38.4
ICD-10 Finland
Oedema of larynx
20.5
9.8
14
7
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
9.8
259
1842
UJC01
NOMESCO Finland
Scopy of lower throat
13.7
9.7
16
12
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
9.5
109
563
J46
ICD-10 Finland
Status asthmaticus
7.7
9.0
20
27
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
8.7
191
1263
N02BE01
ATC
paracetamol; systemic, rectal
1.9
8.6
421
3580
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.1
8.5
104
552
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
8.7
8.4
17
20
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
+∞
8.4
8
*
P01AB01
ATC
metronidazole; oral, rectal
1.8
8.3
185
1221
M79.6
ICD-10 Finland
Pain in limb
1.8
8.3
171
1102
J01FA09
ATC
clarithromycin; systemic
1.9
8.3
158
993
J01AA02
ATC
doxycycline; systemic
1.8
8.2
373
3059
J01FA15
ATC
telithromycin; oral
2.7
8.1
55
218
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.1
7.9
42
143
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.2
7.9
84
420
J01CE02
ATC
phenoxymethylpenicillin; oral
1.7
7.9
349
2823
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.9
7.7
126
749
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.4
7.6
26
61
WX707
NOMESCO Finland
Fiberoscopic intubation
25.4
7.6
10
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
10.2
7.6
14
14
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
7.5
77
379
R03AC02
ATC
salbutamol; inhalant
1.7
7.4
245
1807
ZXA10
NOMESCO Finland
Bilateral
2.1
7.4
85
441
4630A
ICD-9 Finland
Acute tonsillitis[TONSILLITIS ACUTA]
+∞
7.3
7
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.6
7.3
20
37
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
7.2
95
516
DQA10
NOMESCO Finland
Biopsy of larynx
30.5
7.2
9
*
X58
ICD-10 Finland
Exposure to other specified factors
2.2
7.1
75
373
R05
ICPC
Cough
2.0
7.1
101
568
WX110
NOMESCO Finland
Local anesthesy
1.7
7.0
338
2746
R52.9
ICD-10 Finland
Pain, unspecified
2.8
7.0
44
166
R03BA02
ATC
budesonide; inhalant
2.1
6.9
85
450
R13
ICD-10 Finland
Dysphagia
3.2
6.9
34
111
A02BC05
ATC
esomeprazole; systemic
1.7
6.8
188
1311
J39.1
ICD-10 Finland
Other abscess of pharynx
40.6
6.8
8
*
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
22.9
6.7
9
*
R06.0
ICD-10 Finland
Dyspnoea
1.9
6.7
110
651
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.1
6.5
34
115
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
6.5
97
556
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.9
6.4
103
607
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
9.4
6.3
12
13
J01DA06
ATC
[U] cefuroxime; systemic
2.1
6.3
77
406
46309
ICD-8 Finland
Acute tonsillitis, Unspecified
+∞
6.3
6
*
J04.1
ICD-10 Finland
Acute tracheitis
+∞
6.3
6
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
6.2
165
1136
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.3
6.1
52
236
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
6.0
85
477
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
132
558
2.77
21.30
2.1
1.7
—
—
—
0
0
96
385
2.79
16.88
1.7
1.6
—
—
—
0
0
96
393
2.73
16.20
1.7
1.7
—
—
—
0
0
34
76
4.69
14.42
1.8
1.4
—
—
—
0
0
158
853
2.17
14.30
1.7
1.4
—
—
—
0
0
27
52
5.40
13.56
2.0
1.3
—
—
—
0
0
347
2540
1.92
12.78
10.4
8.9
4.3
4.1
e9/l
0.69
303
2223
342
2512
1.89
12.24
6.3
4.6
7.0
6.6
mmol/l
1.62
323
2338
26
57
4.73
11.29
4.3
2.6
58.6
59.0
%
0.05
26
57
31
80
4.04
10.97
1.9
1.4
—
—
—
0
0
25
55
4.71
10.81
4.3
2.4
4.0
4.7
e9/l
0.73
25
55
299
2176
1.78
10.34
6.1
6.6
10.1
11.7
umol/l
3.48
285
2084
160
989
1.86
9.37
2.4
1.9
3.0
2.9
mg/l
0.27
132
839
519
4584
2.34
8.77
20.1
12.0
29.6
23.6
mg/l
2.91
467
3522
56
240
2.48
8.49
1.3
1.3
—
—
—
0
0
15
26
5.90
8.36
2.1
1.6
—
—
—
0
0
15
26
5.90
8.36
2.1
1.6
—
—
—
0
0
15
26
5.90
8.36
2.1
1.6
—
—
—
0
0
32
102
3.26
8.35
2.2
1.6
—
—
—
0
0
57
250
2.42
8.23
1.5
1.6
—
—
—
0
0
20
46
4.47
8.21
1.5
1.3
—
—
—
0
0
17
34
5.12
8.18
1.6
1.3
—
—
—
0
0
408
3362
1.73
8.09
8.9
7.4
75.8
76.8
u/l
0.22
394
3177
160
1030
1.77
8.03
2.6
3.0
1455.2
1200.0
ng/l
0.28
134
878
171
1125
1.74
7.94
4.4
2.8
0.6
0.5
e6/l
0.13
136
827
210
1472
1.67
7.67
4.3
2.9
—
—
—
0
0
239
1732
1.65
7.67
8.1
6.0
1.2
1.2
mmol/l
0.85
221
1575
50
214
2.46
7.61
1.8
1.5
—
—
—
0
0
10
12
8.46
7.60
2.5
1.6
—
—
—
0
0
10
12
8.46
7.60
2.5
1.6
—
—
—
0
0
10
12
8.46
7.60
2.5
1.6
—
—
—
0
0
10
12
8.46
7.60
2.5
1.6
—
—
—
0
0
237
1725
1.64
7.41
5.7
5.1
35.2
36.2
g/l
1.88
223
1614
93
517
1.95
7.39
3.2
2.4
23.7
24.3
%
0.14
79
453
259
1933
1.62
7.28
9.4
6.8
1.2
1.2
mmol/l
0.63
207
1647
74
386
2.05
7.02
1.6
1.8
351.8
374.5
nmol/l
0.43
68
358
14
28
5.10
6.73
1.1
1.0
—
—
—
0
0
453
3921
1.73
6.67
22.4
14.9
13.7
13.6
%
0.84
447
3852
41
172
2.49
6.53
10.9
3.2
24.7
23.9
mmol/l
0.82
36
158
106
644
1.79
6.35
4.2
3.6
0.8
0.8
mmol/l
3.20
98
610
376
3124
1.59
6.33
3.4
3.1
—
—
—
0
0
164
1126
1.64
6.28
3.3
2.4
8308.0
3878.0
umol/l
0.45
138
1002
386
3230
1.59
6.27
4.8
3.7
14.0
10.4
mm/h
4.12
361
3019
103
624
1.79
6.22
3.0
2.3
13.1
14.2
umol/l
0.77
93
587
71
386
1.96
6.00
4.0
3.0
—
—
—
0
0
185
1325
1.58
5.90
2.5
2.6
52.8
57.6
u/l
1.22
175
1243
80
457
1.87
5.83
9.6
8.4
1.3
1.1
mmol/l
0.21
64
362
118
757
1.70
5.82
3.8
3.4
181.9
576.7
ng/l
1.25
81
568
18
50
3.68
5.80
1.7
1.3
—
—
—
0
0
182
1303
1.58
5.79
3.5
3.1
8.2
8.2
mmol/l
0.00
153
1112
11
21
5.32
5.54
1.9
1.2
—
—
—
0
0
86
511
1.80
5.52
2.0
3.2
5.9
8.0
umol/l
0.87
71
460
21
67
3.22
5.52
1.7
1.3
—
—
—
0
0
93
569
1.76
5.41
3.1
2.3
2.3
2.3
g/l
0.46
84
537
84
506
1.77
5.15
7.9
5.9
1.1
1.0
mmol/l
0.14
78
475
509
4654
1.81
4.97
21.6
13.5
139.3
139.7
mmol/l
3.35
501
4552
185
1372
1.51
4.89
3.4
3.4
2.3
2.3
mmol/l
1.12
162
1243
510
4671
1.80
4.88
21.7
13.6
4.0
4.0
mmol/l
0.54
502
4558
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
26
101
2.65
4.87
3.1
2.0
0.3
0.4
u/ml
0.83
14
50
61
339
1.89
4.84
5.9
3.3
2.0
1.9
mmol/l
0.01
53
263
18
57
3.23
4.80
1.7
1.3
—
—
—
0
0
16
47
3.47
4.78
1.3
1.9
32.7
33.3
pg
0.20
16
47
136
950
1.56
4.70
2.1
1.7
2.3
1.1
mg/l
0.58
103
744
391
3380
1.49
4.66
4.2
3.7
14.5
14.6
pmol/l
0.40
354
3100
22
81
2.78
4.56
2.0
1.4
—
—
—
0
0
61
346
1.85
4.55
11.1
7.2
1.1
1.3
mmol/l
1.87
61
330
11
26
4.29
4.37
2.7
2.0
10.8
12.5
%
—
6
13
19
66
2.94
4.37
1.7
1.6
—
—
—
0
0
10
23
4.41
4.10
2.0
2.1
—
—
—
0
0
165
1236
1.47
4.04
4.8
4.0
12.4
9.5
mg/mmol
0.25
114
802
18
64
2.87
3.99
1.3
1.2
—
—
—
0
0
18
64
2.87
3.99
1.3
1.2
—
—
—
0
0
249
2016
1.41
3.99
3.4
2.6
139.2
120.5
ug/l
0.44
228
1880
109
750
1.56
3.98
1.4
1.3
25.9
32.9
iu/ml
0.31
29
243
19
70
2.77
3.95
4.8
2.2
15.5
15.9
%
—
8
40
98
659
1.59
3.95
3.9
2.6
1.7
1.8
e6/l
0.03
52
347
266
2186
1.40
3.88
3.7
3.0
0.0
0.0
estimate
0.00
71
382
15
49
3.12
3.83
1.9
1.3
—
—
—
0
0
213
1687
1.42
3.83
2.4
2.2
74.8
75.0
nmol/l
0.04
190
1536
9
15
6.08
3.83
2.1
1.2
—
—
—
0
0
9
15
6.08
3.83
2.1
1.2
—
—
—
0
0
30
141
2.19
3.78
3.4
1.7
—
—
—
0
0
262
2156
1.39
3.75
3.7
3.0
0.0
0.0
estimate
0.00
76
404
528
4953
1.79
3.73
12.6
9.4
27.2
27.8
u/l
0.33
513
4812
262
2162
1.39
3.66
5.1
4.2
0.0
0.0
estimate
0.00
78
409
13
40
3.30
3.64
2.2
1.4
—
—
—
0
0
151
1132
1.45
3.64
4.0
3.3
0.0
0.0
estimate
0.00
72
394
550
5235
2.12
3.60
28.2
17.8
135.1
137.8
g/l
3.87
542
5177
26
119
2.24
3.50
2.9
3.2
—
—
—
0
0
102
715
1.52
3.41
3.7
2.8
2.4
2.4
mmol/l
0.28
82
636
98
682
1.53
3.39
4.2
2.5
0.9
1.0
e6/l
0.09
53
370
454
4137
1.46
3.39
4.9
4.3
1.9
1.8
mu/l
0.13
416
3835
12
37
3.29
3.36
2.3
1.4
—
—
—
0
0
200
1598
1.39
3.32
2.0
1.8
93.5
95.9
pmol/l
0.31
102
864
254
2110
1.36
3.31
4.7
3.8
—
—
—
0
0
7
11
6.43
3.19
3.1
1.5
—
—
—
0
0
7
11
6.43
3.19
3.1
1.5
—
—
—
0
0
7
11
6.43
3.19
3.1
1.5
—
—
—
0
0
13
44
3.00
3.15
1.2
1.2
—
—
—
0
0
131
982
1.43
3.12
1.3
1.2
2.7
1.4
u/ml
0.37
37
290
27
132
2.10
3.12
2.9
1.6
—
—
—
0
0
160
1244
1.40
3.10
2.5
2.0
151.8
274.9
u/l
1.27
151
1181
97
687
1.50
3.09
1.9
1.6
1256.2
1172.0
nmol/l
0.35
64
532
6
8
7.56
3.06
1.0
1.3
—
—
—
0
0
194
1561
1.37
3.04
3.2
3.6
30.0
31.9
u/l
0.47
183
1499
115
847
1.45
3.00
1.7
1.6
431.5
5479872.5
pmol/l
0.50
92
730
32
171
1.92
2.92
2.6
7.3
1.8
1.7
%
0.36
32
160
25
122
2.10
2.91
1.4
1.2
—
24.8
—
0
7
25
122
2.10
2.91
1.6
1.4
265.2
276.7
ug/g
0.12
17
69
22
102
2.20
2.90
9.8
3.6
107.5
31.4
mg/l
0.43
16
87
22
102
2.20
2.90
9.7
3.6
59.5
118.3
mg/l
0.46
16
86
6
9
6.72
2.87
3.8
6.1
—
—
—
0
0
95
681
1.47
2.85
1.8
1.9
1.5
1.4
%
0.59
83
612
13
47
2.81
2.83
9.2
6.3
12.0
10.6
mg/l
0.45
13
41
9
23
3.96
2.78
2.1
1.2
—
—
—
0
0
191
1553
1.34
2.75
4.0
3.3
35.7
44.6
ng/l
0.37
123
998
469
4353
1.42
2.70
18.1
10.9
86.3
85.3
ml/min/173m2
0.42
409
3531
80
561
1.49
2.68
2.4
1.8
—
—
—
0
0
39
229
1.75
2.67
3.7
3.5
1.0
1.8
mmol/l
0.79
26
171
13
49
2.69
2.64
1.2
1.1
—
—
—
0
0
61
406
1.56
2.59
2.4
2.4
33.8
33.8
u/l
0.00
51
344
42
255
1.70
2.57
3.7
4.3
95.0
81.9
ng/l
0.35
35
235
5
7
7.19
2.55
2.8
1.4
—
—
—
0
0
14
58
2.45
2.38
1.4
1.2
—
—
—
0
0
20
98
2.08
2.34
1.3
1.2
—
32.6
—
0
10
8
23
3.51
2.27
1.6
1.5
13.4
14.2
u/l
—
8
23
6
14
4.32
2.15
1.5
1.6
45.4
64.7
ug/l
—
6
14
85
630
1.41
2.15
2.5
1.9
—
—
—
0
0
145
1174
1.31
2.09
1.7
1.6
1.6
1.4
mmol/l
1.07
122
1016
37
232
1.64
2.04
1.1
1.0
—
—
—
0
0
8
26
3.11
2.02
2.0
1.2
11.9
10.7
u/l
—
8
26
7
21
3.36
1.97
3.0
3.1
685.4
732.7
u/ml
—
7
21
15
71
2.14
1.93
5.9
5.5
359.7
391.7
umol/l
0.51
15
65
21
114
1.87
1.89
1.4
1.3
—
—
—
0
0
25
144
1.77
1.88
2.1
1.9
87.9
89.2
%
0.10
25
133
6
17
3.55
1.84
2.7
2.0
—
—
—
0
0
358
3272
1.25
1.82
3.3
3.2
51.7
47.6
u/l
0.41
335
3114
8
29
2.78
1.79
2.8
1.3
—
—
—
0
0
10
41
2.46
1.76
1.0
1.0
—
—
—
0
0
20
110
1.85
1.75
1.2
1.1
—
—
—
0
0
199
1711
1.25
1.75
4.0
3.1
—
—
—
0
0
447
4202
1.28
1.74
6.4
5.3
40.7
39.3
mmol/mol
1.78
411
3965
127
1036
1.29
1.72
3.4
2.2
—
—
—
0
0
112
902
1.30
1.67
1.6
1.5
18.2
20.8
nmol/l
1.54
101
789
484
4604
1.32
1.67
4.3
4.1
4.6
4.7
mmol/l
0.69
448
4335
6
19
3.18
1.66
1.2
1.2
48.2
10.4
u/l
—
6
14
6
19
3.18
1.66
1.2
1.2
118.7
68.2
u/l
—
6
14
5
14
3.59
1.62
1.2
1.0
—
—
—
0
0
5
14
3.59
1.62
1.6
1.1
—
—
—
0
0
7
26
2.71
1.58
1.0
1.1
—
—
—
0
0
7
26
2.71
1.58
1.1
1.1
—
—
—
0
0
7
26
2.71
1.58
1.0
1.1
—
—
—
0
0
28
176
1.62
1.57
1.8
2.1
1190.9
3190.8
u/l
0.97
11
76
48
342
1.44
1.54
2.9
2.3
70.1
70.0
ml/min/173m2
0.00
23
144
8
33
2.44
1.54
1.1
1.2
—
70.0
—
0
6
21
124
1.72
1.49
1.7
2.4
10.7
11.8
mg/l
0.21
21
116
9
37
2.45
1.48
3.3
3.7
—
—
—
0
0
24
148
1.65
1.46
3.7
1.8
—
—
—
0
0
14
73
1.94
1.45
1.3
1.1
0.6
3.4
u/ml
—
7
27
61
462
1.36
1.40
21.5
20.6
1.1
1.3
inr
0.58
14
61
17
97
1.78
1.36
1.2
1.3
—
—
—
0
0
17
97
1.78
1.36
1.3
1.3
—
—
—
0
0
10
47
2.15
1.34
1.8
1.6
—
—
—
0
0
10
47
2.15
1.34
1.8
1.6
—
—
—
0
0
10
47
2.15
1.34
1.8
1.6
—
—
—
0
0
6
24
2.52
1.30
1.2
1.5
—
100.0
—
0
5
464
4428
1.25
1.30
3.9
3.7
1.4
1.3
mmol/l
1.19
423
4134
10
48
2.10
1.28
1.8
1.5
—
—
—
0
0
10
48
2.10
1.28
1.8
1.5
—
—
—
0
0
15
84
1.81
1.28
1.7
1.5
—
—
—
0
0
479
4590
1.26
1.27
4.3
4.1
1.4
1.4
mmol/l
0.65
441
4296
20
123
1.65
1.25
3.6
1.9
2.9
3.0
g/l
0.29
15
97
21
131
1.63
1.25
2.1
1.8
—
—
—
0
0
88
715
1.27
1.25
1.3
1.3
3.8
11.4
u/ml
1.53
29
293
5
19
2.65
1.22
2.2
2.3
—
—
—
0
0
5
19
2.65
1.22
2.2
2.3
—
—
—
0
0
27
182
1.51
1.18
3.6
3.2
25.7
25.3
mmol/l
0.29
27
175
487
4686
1.25
1.17
4.8
4.5
2.7
2.8
mmol/l
1.42
447
4386
15
87
1.74
1.16
1.4
1.3
1344.0
907.7
e6/l
—
8
75
15
87
1.74
1.16
1.3
1.2
26.8
5.6
e6/l
—
8
71
8
39
2.07
1.15
1.0
1.3
—
—
—
0
0
8
39
2.07
1.15
4.6
2.7
—
—
—
0
0
461
4424
1.21
1.06
4.6
4.1
6.2
5.9
mmol/l
3.29
409
4097
7
33
2.13
1.06
3.3
3.1
—
—
—
0
0
36
264
1.39
1.04
7.7
7.6
25.0
24.5
mmol/l
0.50
36
251
44
334
1.34
1.04
4.1
2.2
3.8
8.7
ug/l
3.14
37
300
9
46
1.97
1.04
1.9
1.6
—
—
—
0
0
5
22
2.28
1.03
1.0
1.1
1170.2
1329.5
miu/ml
—
5
22
7
35
2.01
1.00
1.0
1.2
—
—
—
0
0
7
35
2.01
1.00
1.0
1.2
—
—
—
0
0
20
132
1.53
0.98
2.8
2.3
3.7
3.7
g/l
0.00
20
127
7
36
1.96
0.97
1.0
1.2
—
—
—
0
0
7
36
1.96
0.97
1.0
1.2
—
—
—
0
0
7
36
1.96
0.97
1.0
1.2
—
—
—
0
0
20
133
1.52
0.95
3.9
1.9
—
—
—
0
0
20
133
1.52
0.95
3.9
1.9
4.9
3.8
g/l
0.43
15
95
11
62
1.79
0.94
1.2
1.4
—
—
—
0
0
6
27
2.23
0.93
1.5
1.2
32.6
36.6
nmol/l
—
6
21
23
159
1.47
0.92
1.1
1.4
—
—
—
0
0
6
29
2.08
0.89
1.7
1.8
—
—
—
0
0
454
4376
1.18
0.86
19.3
13.0
40.1
40.6
%
0.66
342
3418
6
31
1.95
0.84
1.0
1.0
—
—
—
0
0
44
552
0.78
0.83
1.5
1.8
—
—
—
0
0
0
24
0.00
0.79
0.0
2.3
—
84.0
—
0
24
14
90
1.57
0.78
1.7
1.5
121.4
114.0
u/ml
—
5
17
43
341
1.28
0.78
2.5
1.8
—
—
—
0
0
17
116
1.48
0.75
3.4
2.3
97.6
66.6
ug/min
0.22
11
67
18
125
1.45
0.73
6.4
3.0
3.9
3.9
mmol/l
0.17
18
116
42
336
1.27
0.73
1.2
1.2
56.8
149.4
iu/ml
3.34
23
145
5
26
1.93
0.70
1.0
1.2
272.4
144.0
iu/ml
—
5
26
7
41
1.72
0.70
1.3
1.2
—
—
—
0
0
14
93
1.52
0.70
1.4
1.2
—
—
—
0
0
7
42
1.67
0.68
1.0
1.0
—
—
—
0
0
10
154
0.64
0.65
1.3
1.5
—
—
—
0
0
13
88
1.49
0.61
1.4
1.3
313.1
241.1
u/ml
—
8
55
0
21
0.00
0.60
0.0
2.9
—
—
—
0
0
10
150
0.66
0.59
1.6
1.5
—
—
—
0
0
6
35
1.72
0.58
1.2
1.1
—
—
—
0
0
7
49
1.43
0.46
2.0
4.7
—
78.5
u/ml
—
0
14
27
219
1.24
0.46
2.7
2.6
0.1
0.1
e6/l
0.07
27
211
7
50
1.40
0.45
1.0
1.1
—
—
—
0
0
5
31
1.62
0.43
1.4
1.5
0.6
1.0
u/field
—
5
21
5
31
1.62
0.43
1.4
1.5
—
—
—
0
0
20
250
0.79
0.42
1.3
1.5
—
—
—
0
0
8
58
1.38
0.41
1.0
1.1
—
—
—
0
0
19
150
1.28
0.40
1.2
1.4
275.6
226.0
miu/ml
0.22
14
75
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
36
419
0.85
0.39
4.7
4.9
4.5
32.0
ug/l
0.82
31
347
9
68
1.33
0.37
1.0
1.1
127.2
112.8
%
—
9
62
9
71
1.27
0.36
1.0
1.1
—
—
—
0
0
16
200
0.79
0.35
2.4
2.6
22.0
39.6
u/ml
0.71
16
192
10
73
1.38
0.34
1.1
1.1
—
—
—
0
0
28
237
1.19
0.34
1.6
1.3
—
—
—
0
0
6
45
1.34
0.34
1.3
1.1
1.5
1.4
nmol/l
—
6
39
178
1693
1.07
0.32
4.4
4.4
1.9
2.2
ug/l
0.55
158
1530
11
83
1.33
0.32
2.4
1.7
—
—
—
0
0
31
267
1.17
0.32
2.6
1.8
—
—
—
0
0
45
505
0.88
0.31
4.0
4.2
32.1
30.6
%
0.46
27
348
7
55
1.28
0.30
1.1
1.5
2.0
2.2
ug/l
—
7
49
16
130
1.24
0.29
1.6
1.1
—
—
—
0
0
16
130
1.24
0.29
1.6
1.1
—
—
—
0
0
14
171
0.81
0.26
1.2
1.4
—
—
—
0
0
11
86
1.28
0.26
1.3
1.8
—
—
—
0
0
74
686
1.09
0.26
1.5
1.5
—
—
—
0
0
5
39
1.28
0.23
1.4
1.5
—
—
—
0
0
12
146
0.82
0.22
1.1
1.5
—
—
—
0
0
15
178
0.84
0.22
1.6
1.8
—
—
—
0
0
5
42
1.19
0.21
1.0
1.8
89.3
16.3
ug/l
—
5
42
0
11
0.00
0.21
0.0
1.1
—
367.2
—
0
6
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
8
102
0.78
0.21
1.9
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
6
53
1.13
0.18
1.0
1.1
—
—
—
0
0
16
138
1.16
0.17
1.7
1.7
180.4
210.1
pmol/l
0.52
16
127
12
141
0.85
0.16
1.1
1.4
—
—
—
0
0
12
141
0.85
0.16
1.1
1.4
—
—
—
0
0
8
70
1.14
0.16
1.9
1.6
—
—
—
0
0
6
76
0.79
0.15
1.0
1.1
—
—
—
0
0
12
140
0.85
0.15
1.1
1.4
—
—
—
0
0
12
140
0.85
0.15
1.1
1.4
—
—
—
0
0
7
87
0.80
0.14
1.3
1.5
—
—
—
0
0
53
502
1.06
0.12
8.8
6.3
—
—
—
0
0
103
1000
1.04
0.10
2.6
2.8
0.7
0.8
ug/l
0.36
66
599
14
129
1.09
0.05
1.9
1.7
—
—
—
0
0
13
122
1.07
0.02
1.3
1.5
—
—
—
0
0
95
946
1.01
0.00
4.1
3.3
1.0
1.0
kg/l
0.45
13
133
12
119
1.01
0.00
2.5
1.7
5.9
5.0
iu/l
—
7
41
12
121
0.99
0.00
1.8
1.3
—
—
—
0
0
18
179
1.01
0.00
1.6
1.6
33.8
39.9
nmol/l
0.90
18
169
136
1358
1.00
0.00
3.6
3.9
21.0
21.3
%
0.06
60
573
6
63
0.95
0.00
1.3
1.5
12.5
21.6
u/l
—
6
50
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
105.0
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint J10_EPIGLOTTITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_EPIGLOTTITIS | 1.186 [0.94, 1.5] | 0.152 |
| Birth year | 0.993 [0.98, 1.0] | 0.127 |
During the follow-up period (1.1.1998 — 31.12.2019), 121 out of 1403 females with J10_EPIGLOTTITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_EPIGLOTTITIS | 1.459 [1.22, 1.74] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 282 out of 1993 males with J10_EPIGLOTTITIS died.
Mortality risk
Mortality risk for people of age
years, who have J10_EPIGLOTTITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.084% | 0.284% |
| 5 | 0.639% | 1.731% |
| 10 | 1.61% | 4.157% |
| 15 | 3.083% | 7.877% |
| 20 | 5.572% | 13.424% |
Relationships between endpoints
↥Index endpoint: J10_EPIGLOTTITIS – Acute epiglottitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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