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Galactorrhea

Endpoint Browser PheWeb

N14_GALACTORRHEA

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N64.3
  • Hospital discharge: ICD-9 — 2531A
  • Cause of death: ICD-10 — N64.3
  • Cause of death: ICD-9 — 2531A

2 out of 7 registries used, show all original rules.

379

4. Check minimum number of events

None

379

5. Include endpoints

None

379

6. Filter based on genotype QC (FinnGen only)

379

Control definitions (FinnGen only)

Control exclude
N14_BREAST

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Parent code in ICD-10
N60-N64
Name in latin
Aliae morbositates mammae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2252 2252 -
Only index persons 2207 2207 -
Unadjusted period prevalence (%)
Whole population 0.06 0.06 -
Only index persons 0.08 0.08 -
Median age at first event (years)
Whole population - 34.59 -
Only index persons - 34.51 -

-FinnGen-

Key figures

All Female Male
Number of individuals 379 379 -
Unadjusted period prevalence (%) 0.13 0.13 -
Median age at first event (years) 33.75 33.75 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
345
Matched controls
3450
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N64.3
ICD-10 Finland
Galactorrhoea not associated with childbirth
3388.5
323.0
305
7
2531A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Other and unspecified anterior pituitary hyperfunction[HYPERPROLACTINAEMIA]
+∞
42.6
40
*
E22.1
ICD-10 Finland
Hyperprolactinaemia
25.7
33.7
47
21
G02CB01
ATC
bromocriptine; systemic
17.1
33.6
54
37
N64.5
ICD-10 Finland
Other signs and symptoms in breast
19.3
23.2
35
20
G02CB03
ATC
cabergoline; oral (prolactine inhibitors)
44.8
20.7
25
6
N04BC06
ATC
cabergoline; oral (dopamine agonists)
30.7
17.6
23
8
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.3
12.8
184
1135
N64.9
ICD-10 Finland
Disorder of breast, unspecified
72.6
12.7
14
*
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
13.9
12.6
21
16
M54.5
ICD-10 Finland
Low back pain
2.4
12.5
148
828
N62
ICD-10 Finland
Hypertrophy of breast
48.4
12.0
14
*
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
10.2
11.9
23
24
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
4.4
11.1
40
99
R51.80
ICD-10 Finland
Headache
2.6
10.8
88
398
N06AB04
ATC
citalopram; systemic
2.5
10.7
101
496
N63
ICD-10 Finland
Unspecified lump in breast
4.1
10.5
41
109
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
10.1
89
419
O92.6
ICD-10 Finland
Galactorrhoea
41.4
10.0
12
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.0
9.8
60
227
N05AH04
ATC
quetiapine; oral
2.5
9.4
80
367
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.2
9.4
128
739
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
8.8
74
338
M03BC01
ATC
orphenadrine (citrate); systemic
2.2
8.8
113
636
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.3
8.6
43
142
P01AB01
ATC
metronidazole; oral, rectal
2.0
8.5
175
1185
N06AB10
ATC
escitalopram; oral
2.2
8.5
108
603
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
8.4
155
1005
N76.0
ICD-10 Finland
Acute vaginitis
2.9
8.4
51
192
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.2
8.4
44
151
N03AX12
ATC
gabapentin; oral
2.6
8.2
61
260
N02BE01
ATC
paracetamol; systemic, rectal
2.4
8.0
299
2525
C07AA05
ATC
propranolol; systemic
2.2
8.0
98
536
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.8
7.9
52
203
ZXA05
NOMESCO Finland
Left side
2.4
7.9
74
358
R03AC02
ATC
salbutamol; inhalant
1.9
7.7
205
1503
N06AX21
ATC
duloxetine; oral
2.6
7.6
55
231
M25.5
ICD-10 Finland
Pain in joint
2.0
7.5
118
711
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.2
7.4
79
406
N61
ICD-10 Finland
Inflammatory disorders of breast
5.7
7.3
20
37
A06AC01
ATC
ispaghula (psylla seeds); oral
2.2
7.3
84
445
HA1AA
NOMESCO Finland
X-ray mammography
3.4
7.3
34
107
J01DB01
ATC
cefalexin; oral
2.2
7.2
294
2493
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
7.0
68
331
X21
ICPC
Breast sympt/compl female other
6.1
7.0
18
31
N03AX16
ATC
pregabalin; oral
2.1
7.0
84
453
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.7
7.0
29
83
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.5
7.0
31
94
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.1
6.9
36
123
N05AA02
ATC
levomepromazine; systemic
5.5
6.9
19
36
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.2
6.9
35
118
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
6.8
77
402
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
6.7
54
238
F61.0
ICD-10 Finland
Mixed personality disorders
6.1
6.7
17
29
J01DA01
ATC
[U] cefalexin; systemic
1.8
6.6
229
1791
SPAT1263
SPAT
Sampling
1.8
6.6
156
1077
H02AB06
ATC
prednisolone; systemic
1.8
6.6
157
1089
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.0
6.5
37
133
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.6
6.5
45
185
HAB20
NOMESCO Finland
Excision of lactiferous duct
71.1
6.4
7
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.1
6.4
76
404
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.9
6.4
37
136
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
3.5
6.3
28
85
ULA02
NOMESCO Finland
Kolposcopy
2.2
6.3
66
334
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.2
6.3
68
349
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
4.7
6.3
20
45
A02BC05
ATC
esomeprazole; systemic
1.8
6.3
133
880
G02CB04
ATC
quinagolide; oral
+∞
6.3
6
*
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
3.3
6.2
30
98
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
6.1
48
208
S29
ICPC
Skin symptom/complaint other
2.3
6.0
57
273

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
91
237
4.74
33.20
2.3
1.6
617.3
292.1
mu/l
0.50
84
214
46
71
7.24
29.24
2.4
1.3
—
—
—
0
0
23
15
16.26
26.45
1.5
1.6
—
—
—
0
0
151
867
2.23
12.44
3.2
2.2
53.7
54.7
u/l
0.11
136
807
302
2331
2.45
11.41
4.4
3.7
8.6
9.6
mm/h
1.23
291
2169
224
1580
2.02
10.01
4.0
3.9
6.1
6.3
mmol/l
0.70
209
1419
206
1440
1.94
9.13
5.6
5.1
9.0
9.2
umol/l
0.31
196
1358
123
734
2.00
8.56
2.2
1.9
94.5
135.0
u/l
2.37
118
696
185
1272
1.89
8.39
5.1
5.5
1.2
1.2
mmol/l
1.27
165
1072
113
659
2.02
8.36
1.5
1.3
18.7
27.6
iu/ml
0.75
40
221
161
1061
1.90
8.30
3.4
4.2
37.2
36.9
g/l
0.36
153
1000
327
2745
2.39
8.12
5.8
4.4
14.3
14.3
pmol/l
0.16
315
2576
63
295
2.36
8.07
2.2
2.1
371.5
369.5
nmol/l
0.04
56
274
286
2288
2.02
7.94
7.7
6.4
69.2
73.7
u/l
1.81
267
2147
355
3117
3.19
7.70
13.4
9.9
139.5
139.6
mmol/l
0.44
349
3034
65
315
2.28
7.69
1.6
1.4
—
—
—
0
0
220
1628
1.84
7.63
6.9
5.4
2.0
2.0
e9/l
0.31
200
1465
213
1565
1.82
7.52
7.1
5.4
0.0
0.0
e9/l
0.89
187
1375
212
1557
1.82
7.48
7.1
5.4
0.5
0.5
e9/l
0.07
187
1372
355
3126
3.14
7.47
13.7
10.0
3.9
3.9
mmol/l
0.49
350
3030
165
1125
1.83
7.43
4.4
4.9
1.2
1.2
mmol/l
2.29
152
1028
238
1818
1.83
7.30
11.4
8.1
4.0
3.9
e9/l
0.22
206
1591
111
674
1.91
7.16
4.6
3.2
1.0
1.0
kg/l
0.28
25
94
84
468
2.02
6.93
2.1
2.2
76.9
100.0
ug/g
0.53
70
374
136
890
1.82
6.89
3.0
2.3
—
—
—
0
0
217
1640
1.76
6.63
7.3
5.7
0.2
0.2
e9/l
0.46
195
1462
144
968
1.79
6.62
7.2
5.3
—
—
—
0
0
192
1407
1.74
6.50
7.6
5.4
0.7
0.7
%
0.08
179
1309
34
136
2.65
6.05
1.2
1.2
14.6
12.7
u/l
0.25
26
109
40
174
2.45
6.00
2.3
1.2
—
—
—
0
0
134
906
1.74
5.91
3.0
3.0
2.3
2.4
mmol/l
0.29
121
820
188
1396
1.69
5.86
2.2
2.0
—
—
—
0
0
201
1523
1.68
5.77
7.6
5.2
56.7
56.7
%
0.03
189
1433
202
1534
1.68
5.74
7.8
5.4
29.6
29.6
%
0.01
187
1434
243
1939
1.71
5.71
3.3
2.8
—
—
—
0
0
104
663
1.78
5.58
1.4
1.3
3.8
12.2
u/ml
1.84
34
286
59
313
2.05
5.51
3.3
2.1
7448.1
3731.3
u/l
0.26
13
133
194
1469
1.66
5.49
7.7
5.6
7.9
7.8
%
0.21
181
1382
42
195
2.30
5.46
4.3
2.3
—
—
—
0
0
193
1461
1.65
5.46
7.6
5.3
2.8
2.7
%
0.34
180
1363
85
515
1.84
5.37
1.5
1.3
613.3
604.4
titre
0.01
18
108
268
2225
1.70
5.15
5.3
3.9
—
—
—
0
0
112
751
1.70
4.95
1.6
1.4
1.9
2.1
g/l
0.73
62
480
80
488
1.81
4.92
2.4
2.3
485.4
545.0
mosm/kgh2o
1.56
64
418
226
1813
1.61
4.82
3.2
2.9
65.6
63.4
ug/l
0.16
219
1710
104
697
1.68
4.57
3.8
3.1
—
—
—
0
0
84
533
1.74
4.49
3.2
3.4
—
—
—
0
0
112
769
1.65
4.47
3.4
3.7
7.4
7.4
ph
0.18
15
139
201
1588
1.57
4.42
5.7
4.3
0.0
0.0
estimate
0.50
32
318
14
40
3.60
4.37
1.1
1.3
—
—
nmol/l
—
0
0
39
193
2.14
4.37
3.2
1.4
—
—
—
0
0
30
135
2.33
4.21
3.2
1.6
—
—
—
0
0
124
887
1.59
4.15
1.4
1.3
2.0
2.1
u/ml
0.02
29
262
14
42
3.42
4.08
1.1
1.2
—
—
—
0
0
52
295
1.88
4.00
1.3
1.1
—
—
—
0
0
353
3255
2.23
3.96
14.8
10.0
14.6
18.5
mg/l
2.40
289
2455
38
194
2.07
3.94
3.2
1.4
—
—
—
0
0
200
1605
1.52
3.93
4.3
3.2
0.0
0.0
estimate
0.50
33
312
118
844
1.58
3.91
6.2
5.2
1.4
1.1
inr
0.54
31
285
38
195
2.05
3.89
3.2
1.4
—
—
—
0
0
343
3134
1.99
3.88
6.8
5.1
1.6
2.1
mu/l
0.72
335
2971
54
314
1.84
3.85
2.0
2.4
5.3
5.0
umol/l
0.08
42
262
11
29
3.88
3.83
1.2
1.9
—
—
—
0
0
35
176
2.09
3.78
1.4
1.4
—
—
—
0
0
197
1585
1.51
3.76
4.2
3.1
0.0
0.0
estimate
0.00
27
315
25
110
2.36
3.70
2.9
2.5
—
—
—
0
0
42
229
1.94
3.64
1.2
1.2
—
—
—
0
0
21
86
2.53
3.62
4.1
1.6
—
—
—
0
0
136
1023
1.51
3.54
2.1
1.8
96.6
99.3
pmol/l
0.29
78
547
35
181
2.03
3.52
3.4
1.4
—
—
—
0
0
81
543
1.63
3.48
2.0
2.4
7.2
9.6
e6/l
0.53
71
476
108
777
1.55
3.44
8.8
6.2
—
—
—
0
0
36
190
1.99
3.43
3.4
1.5
—
—
—
0
0
362
3401
2.44
3.38
11.4
8.4
24.7
23.8
u/l
0.36
357
3306
129
970
1.50
3.33
2.3
1.9
—
—
—
0
0
27
132
2.13
3.15
1.8
1.6
—
—
—
0
0
16
62
2.65
3.08
1.7
1.7
—
—
—
0
0
73
494
1.59
3.00
1.6
1.5
—
—
—
0
0
17
69
2.53
3.00
2.5
2.7
—
—
—
0
0
30
156
2.00
2.99
3.3
1.4
—
—
—
0
0
20
88
2.34
2.99
1.4
1.3
306.2
372.8
mg/l
1.46
20
80
56
357
1.67
2.92
1.3
1.3
24.2
26.9
iu/l
0.23
46
313
6
9
6.75
2.87
3.8
1.7
11.4
17.0
umol/l
—
6
9
326
2992
1.64
2.85
4.3
3.6
5.6
5.6
mmol/l
0.18
316
2805
65
434
1.60
2.83
2.1
2.4
2.4
2.4
mmol/l
0.01
58
382
300
2710
1.51
2.73
5.1
4.3
37.2
37.9
mmol/mol
0.77
287
2553
18
79
2.34
2.72
1.1
1.1
6.5
4.3
u/ml
0.26
12
36
59
389
1.61
2.70
1.2
1.1
—
—
—
0
0
17
73
2.39
2.69
1.1
1.1
6.3
0.8
u/ml
—
10
30
53
341
1.64
2.67
1.3
1.3
—
—
—
0
0
19
87
2.25
2.62
1.2
1.3
305.6
316.4
ug/g
—
9
52
115
881
1.44
2.61
3.2
2.7
11.1
16.9
ng/l
1.93
50
408
35
203
1.80
2.55
1.3
1.3
231.5
255.9
miu/ml
0.18
12
102
35
203
1.80
2.55
3.4
3.2
—
—
—
0
0
36
212
1.77
2.50
15.9
13.5
1.2
1.2
inr
—
10
38
364
3471
2.23
2.50
14.2
9.3
—
—
—
0
0
62
422
1.56
2.49
4.1
2.9
362.0
402.0
ng/l
0.04
33
225
99
745
1.45
2.45
2.3
2.1
2.6
2.7
mg/l
0.14
92
637
97
728
1.45
2.44
2.8
2.5
—
—
—
0
0
51
334
1.61
2.41
2.0
1.9
—
—
—
0
0
95
712
1.45
2.40
2.8
2.5
0.2
0.3
e6/l
0.51
79
510
103
785
1.43
2.38
2.8
2.7
16.2
72.5
e6/l
1.89
85
568
168
1396
1.37
2.31
8.8
7.5
0.0
0.0
e9/l
0.99
141
1149
59
404
1.55
2.31
1.8
1.6
1125.9
1121.7
nmol/l
0.01
50
315
6
13
4.67
2.28
1.2
1.2
—
—
—
0
0
151
1246
1.35
2.14
3.8
2.9
—
—
—
0
0
106
833
1.38
2.03
4.5
3.4
0.0
0.0
estimate
0.80
33
322
46
308
1.56
2.00
1.4
1.3
—
—
—
0
0
18
91
2.03
1.98
1.1
1.2
0.2
1.4
u/ml
—
8
35
54
376
1.51
1.97
1.3
1.2
204.8
172.3
iu/ml
0.19
15
155
6
16
3.79
1.94
2.5
4.1
—
—
—
0
0
30
182
1.70
1.92
2.7
3.7
60.3
77.6
ng/l
1.29
22
164
19
102
1.91
1.79
3.5
5.3
—
—
—
0
0
27
163
1.71
1.77
1.1
1.1
—
—
—
0
0
20
110
1.86
1.76
1.2
1.2
—
—
—
0
0
11
48
2.33
1.72
4.5
3.1
—
—
—
0
0
20
113
1.81
1.64
1.5
1.2
—
—
—
0
0
23
136
1.74
1.63
1.1
1.2
—
—
—
0
0
27
169
1.64
1.57
2.6
3.2
3.0
2.0
mmol/l
0.92
21
129
84
662
1.35
1.56
2.0
2.3
295.4
6018.5
umol/l
3.00
76
601
14
72
1.98
1.50
1.4
1.3
—
—
—
0
0
40
278
1.49
1.50
3.6
3.8
4.6
4.6
pmol/l
0.19
34
250
11
53
2.11
1.40
3.1
2.2
—
—
—
0
0
121
1019
1.28
1.38
3.9
3.1
66.6
59.6
e6/l
0.07
88
634
6
23
2.63
1.37
2.0
2.0
—
—
—
0
0
18
107
1.72
1.28
4.3
7.3
24.9
24.9
mmol/l
0.01
18
102
374
3675
2.34
1.27
23.8
15.3
133.8
133.0
g/l
0.79
374
3646
97
805
1.28
1.24
4.1
4.1
—
—
—
0
0
89
731
1.28
1.23
2.2
1.6
0.7
0.8
mg/l
0.33
71
532
21
132
1.63
1.23
1.7
2.0
4.5
5.6
iu/l
—
7
52
8
37
2.19
1.22
1.4
1.3
—
—
—
0
0
5
19
2.65
1.22
1.4
2.9
—
—
—
0
0
171
1519
1.23
1.19
4.3
3.8
—
—
—
0
0
12
64
1.90
1.19
4.1
6.5
1.1
1.2
mmol/l
0.19
12
56
8
38
2.13
1.19
1.3
1.2
—
—
—
0
0
34
242
1.44
1.16
1.4
1.3
—
25.5
—
0
14
80
653
1.29
1.16
3.4
2.8
—
—
—
0
0
19
293
0.63
1.16
3.6
3.3
—
—
—
0
0
18
111
1.65
1.14
1.5
1.8
—
—
—
0
0
26
176
1.51
1.13
2.6
3.2
—
—
—
0
0
15
89
1.71
1.09
8.5
6.2
—
—
—
0
0
87
726
1.26
1.06
3.9
3.0
8.1
7.5
mmol/l
0.45
77
628
67
542
1.29
1.05
1.5
1.5
440.8
47468801.3
pmol/l
1.07
59
474
5
22
2.29
1.03
1.2
1.3
—
—
—
0
0
5
22
2.29
1.03
1.2
1.6
—
—
—
0
0
5
22
2.29
1.03
1.0
1.4
2.0
1.9
mmol/l
—
5
22
110
948
1.23
1.00
3.7
2.7
—
—
—
0
0
16
100
1.63
0.98
2.6
2.1
—
—
—
0
0
328
3153
1.30
0.96
18.2
10.7
39.1
39.6
%
0.44
258
2599
6
27
2.24
0.94
1.7
1.9
—
—
—
0
0
32
236
1.39
0.93
4.8
2.2
3.9
4.2
e9/l
0.42
24
207
43
335
1.32
0.90
2.3
2.4
25.1
22.8
%
0.46
35
291
6
29
2.09
0.89
1.3
1.2
—
—
—
0
0
27
197
1.40
0.85
1.0
1.1
—
—
—
0
0
6
31
1.95
0.84
1.3
1.1
150.8
193.5
mg/l
—
6
24
32
242
1.35
0.82
3.6
3.4
—
—
—
0
0
6
32
1.89
0.82
1.8
1.1
33.5
25.8
mg/l
—
6
22
31
234
1.35
0.80
4.6
5.8
104.4
104.6
mmol/l
0.20
31
229
11
66
1.69
0.79
3.2
4.7
—
—
—
0
0
28
209
1.37
0.78
1.5
1.2
—
—
—
0
0
14
91
1.56
0.76
1.6
3.7
0.6
0.4
g/l
—
6
31
43
344
1.28
0.76
1.3
1.3
—
—
—
0
0
309
2972
1.21
0.75
3.6
3.2
1.3
1.2
mmol/l
1.16
293
2802
7
38
1.86
0.74
1.1
1.1
—
—
—
0
0
7
39
1.81
0.73
7.4
3.9
30.9
22.3
mu/l
—
7
39
120
1074
1.17
0.72
2.0
1.9
—
—
—
0
0
5
26
1.94
0.71
1.0
1.1
—
—
—
0
0
17
118
1.46
0.70
2.7
1.9
—
—
—
0
0
68
583
1.20
0.66
1.6
1.4
20.3
21.9
nmol/l
0.43
62
502
10
62
1.63
0.65
1.2
1.2
—
—
—
0
0
5
29
1.73
0.64
2.6
1.6
—
—
—
0
0
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
26
200
1.32
0.62
3.8
4.0
18.8
7.4
ug/l
0.32
19
153
321
3115
1.20
0.60
4.1
3.6
4.8
4.9
mmol/l
0.73
312
2957
39
472
0.81
0.60
1.3
1.3
—
—
—
0
0
8
54
1.49
0.57
3.5
4.1
3.8
3.7
mmol/l
—
8
49
27
212
1.29
0.57
5.3
6.9
16.1
13.3
kpa
0.66
27
205
27
212
1.29
0.57
5.3
6.9
5.1
5.1
kpa
0.01
27
204
14
98
1.45
0.57
1.1
1.2
—
—
—
0
0
14
98
1.45
0.57
5.2
8.6
—
—
—
0
0
47
396
1.21
0.56
1.2
1.2
—
—
—
0
0
39
322
1.24
0.56
1.4
1.4
—
—
—
0
0
6
38
1.59
0.54
1.5
2.1
—
—
—
0
0
27
214
1.28
0.54
5.1
6.8
1.9
1.3
mmol/l
0.44
17
165
323
3146
1.18
0.52
4.3
3.9
2.9
2.9
mmol/l
0.13
314
2966
16
118
1.37
0.51
3.5
5.2
26.2
24.8
mmol/l
0.67
16
118
58
504
1.18
0.51
1.9
2.0
—
—
—
0
0
99
899
1.14
0.49
1.8
1.7
—
—
—
0
0
19
146
1.32
0.48
3.9
2.6
76.6
76.2
e9/l
—
10
102
10
68
1.48
0.47
1.2
1.2
—
—
—
0
0
7
48
1.47
0.47
2.1
1.3
—
—
—
0
0
28
228
1.25
0.46
1.9
2.4
0.2
0.2
g/l
0.57
22
219
28
229
1.24
0.45
1.3
1.4
—
—
—
0
0
48
551
0.85
0.44
1.6
1.4
—
—
—
0
0
123
1324
0.89
0.44
2.3
2.3
—
—
—
0
0
5
33
1.52
0.41
1.6
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
5
34
1.48
0.40
3.0
2.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
29.4
—
0
18
5
36
1.39
0.38
1.4
2.5
—
—
—
0
0
14
107
1.32
0.37
1.0
1.1
—
—
—
0
0
6
41
1.47
0.36
1.3
2.8
8.9
9.4
kpa
—
6
41
6
41
1.47
0.36
1.3
2.8
5.1
5.0
kpa
—
6
41
5
80
0.62
0.35
6.0
2.7
1.4
1.4
mg/l
—
5
72
6
43
1.40
0.35
1.2
1.3
—
—
—
0
0
22
182
1.22
0.34
4.6
5.4
1.3
1.2
mmol/l
0.13
22
176
102
1091
0.91
0.32
1.7
1.7
—
—
—
0
0
19
228
0.82
0.30
1.4
1.4
—
—
—
0
0
8
107
0.74
0.29
8.6
7.6
24.5
23.9
mmol/l
—
8
102
8
65
1.24
0.27
3.5
4.1
1.2
1.3
mmol/l
—
8
65
20
234
0.85
0.25
1.4
1.5
—
—
—
0
0
18
152
1.19
0.24
6.1
7.3
—
—
—
0
0
315
3101
1.09
0.24
4.1
3.6
1.5
1.6
mmol/l
2.14
306
2930
5
38
1.32
0.23
1.6
1.3
—
—
—
0
0
7
94
0.74
0.22
1.0
1.1
—
—
—
0
0
7
94
0.74
0.22
1.0
1.1
—
—
—
0
0
10
79
1.27
0.22
1.8
1.1
—
—
—
0
0
14
116
1.21
0.22
1.3
1.5
0.2
0.4
nmol/l
—
9
100
78
733
1.08
0.22
1.6
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
2.4
—
—
—
0
0
0
14
0.00
0.20
0.0
3.8
—
—
—
0
0
6
51
1.18
0.19
1.0
1.0
—
—
—
0
0
6
52
1.16
0.19
1.5
1.4
—
—
—
0
0
6
53
1.13
0.19
1.0
1.1
—
—
—
0
0
20
226
0.88
0.17
1.4
1.4
—
—
—
0
0
32
350
0.91
0.17
1.6
1.7
—
—
—
0
0
80
764
1.06
0.15
1.9
1.7
1.7
1.4
mmol/l
1.71
73
670
29
315
0.91
0.14
1.4
1.4
—
—
—
0
0
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
5
60
0.83
0.08
1.4
1.1
—
—
—
0
0
8
94
0.85
0.07
3.0
3.5
—
—
—
0
0
62
608
1.02
0.03
3.7
3.3
36.6
167.4
mg/l
0.56
37
392
11
118
0.93
0.03
1.0
1.3
2.9
2.9
ug/l
0.00
11
106
11
118
0.93
0.03
8.5
8.1
0.8
0.6
%
0.60
11
118
13
138
0.94
0.02
1.5
1.7
—
—
—
0
0
11
117
0.94
0.02
8.5
8.2
94.3
94.7
%
0.17
11
117
11
117
0.94
0.02
8.5
8.1
2.2
1.2
%
0.59
11
117
63
631
1.00
0.00
4.3
4.0
11.3
9.3
mg/mmol
0.11
36
391
6
59
1.02
0.00
2.2
3.2
5.1
4.5
e9/l
—
6
59
5
52
0.96
0.00
1.0
1.4
—
30.1
—
0
5
0
5
0.00
0.00
0.0
3.0
—
14.5
—
0
5
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
1.4
—
0
5
0
8
0.00
0.00
0.0
2.0
—
1.2
—
0
8
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
6
67
0.89
0.00
1.0
1.5
—
—
—
0
0
6
60
1.00
0.00
2.5
3.6
57.8
58.2
%
—
6
60
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint N14_GALACTORRHEA and mortality.

Females

Parameter HR [95% CI] p-value
N14_GALACTORRHEA 1.223 [0.94, 1.58] 0.127
Birth year 0.998 [0.99, 1.01] 0.625

During the follow-up period (1.1.1998 — 31.12.2019), 61 out of 1805 females with N14_GALACTORRHEA died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_GALACTORRHEA.

N-year risk Females Males
1 0.156% No data
5 0.657% No data
10 1.85% No data
15 3.8% No data
20 6.645% No data

Relationships between endpoints

↥

Index endpoint: N14_GALACTORRHEA – Galactorrhea

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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