Galactorrhea

N14_GALACTORRHEA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N64.3
  • Hospital discharge: ICD-9 2531A
  • Cause of death: ICD-10 N64.3
  • Cause of death: ICD-9 2531A

2 out of 7 registries used, show all original rules.

388

4. Check minimum number of events

None

388

5. Include endpoints

None

388

6. Filter based on genotype QC (FinnGen only)

375

Control definitions (FinnGen only)

Control exclude
N14_BREAST

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Parent code in ICD-10
N60-N64
Name in latin
Aliae morbositates mammae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2252 2252 -
Only index persons 2207 2207 -
Unadjusted period prevalence (%)
Whole population 0.06 0.06 -
Only index persons 0.08 0.08 -
Median age at first event (years)
Whole population - 34.59 -
Only index persons - 34.51 -

-FinnGen-

Key figures

All Female Male
Number of individuals 375 375 -
Unadjusted period prevalence (%) 0.13 0.13 -
Median age at first event (years) 34.02 34.02 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
388
Matched controls
3880
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N64.3
ICD-10 Finland
Galactorrhoea not associated with childbirth
3965.9
307.7
344
7
E22.1
ICD-10 Finland
Hyperprolactinaemia
28.4
77.8
54
22
G02CB01
ATC
bromocriptine; systemic
12.5
55.2
58
54
2531A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Other and unspecified anterior pituitary hyperfunction[HYPERPROLACTINAEMIA]
+∞
46.8
44
*
N64.5
ICD-10 Finland
Other signs and symptoms in breast
12.3
42.3
44
40
G02CB03
ATC
cabergoline; oral
22.3
20.3
29
14
N04BC06
ATC
cabergoline; oral
29.6
19.0
25
9
N63
ICD-10 Finland
Unspecified lump in breast
4.2
18.9
55
147
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
8.3
18.5
25
32
O92.6
ICD-10 Finland
Galactorrhoea
177.3
16.6
17
*
N06AB04
ATC
citalopram; systemic
2.7
16.1
114
522
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
15.1
111
515
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.3
14.7
214
1345
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.3
14.0
160
903
N62
ICD-10 Finland
Hypertrophy of breast
55.4
13.9
16
*
R51.80
ICD-10 Finland
Headache
2.5
13.9
106
499
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.4
13.6
53
172
N61
ICD-10 Finland
Inflammatory disorders of breast
5.9
13.5
25
45
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
13.6
13.1
22
17
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
12.5
187
1163
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
3.5
12.1
45
142
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
12.0
71
293
N64.9
ICD-10 Finland
Disorder of breast, unspecified
19.7
11.7
17
9
M54.5
ICD-10 Finland
Low back pain
2.1
11.5
179
1123
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.0
11.0
54
201
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.7
11.0
36
104
N06AB10
ATC
escitalopram; oral
2.2
10.7
128
722
N03AX16
ATC
[U] pregabalin
2.3
10.6
100
511
A04
ICPC
Weakness/tiredness general
2.5
10.6
74
331
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.4
10.4
81
380
N06AX21
ATC
duloxetine; oral
2.5
10.2
71
317
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.0
10.1
29
76
X21
ICPC
Breast sympt/compl female other
5.0
10.1
22
46
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.3
10.1
90
448
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.3
10.1
94
477
P01AB01
ATC
metronidazole; oral, rectal
2.0
10.0
200
1352
N76.0
ICD-10 Finland
Acute vaginitis
2.6
9.9
65
281
N06AX12
ATC
bupropion; oral
2.8
9.9
52
201
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.0
9.6
46
169
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
9.6
82
401
M25.5
ICD-10 Finland
Pain in joint
2.0
9.3
158
1002
N06AX16
ATC
venlafaxine; oral
2.3
9.2
83
415
N05AH04
ATC
quetiapine; oral
2.2
9.1
94
496
R42
ICD-10 Finland
Dizziness and giddiness
2.3
9.1
84
424
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
9.0
108
603
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
8.9
54
225
G43.9
ICD-10 Finland
Migraine, unspecified
2.6
8.8
53
220
SPAT1263
SPAT
Sampling
1.9
8.7
178
1194
M03BC01
ATC
orphenadrine (citrate); systemic
2.0
8.7
122
721
N03AX12
ATC
[U] gabapentin; oral
2.3
8.6
73
354
ULA02
NOMESCO Finland
Kolposcopy
2.2
8.6
81
412
HAB20
NOMESCO Finland
Excision of lactiferous duct
92.0
8.4
9
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.8
8.4
44
169
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
3.2
8.3
33
108
C07AA05
ATC
propranolol; systemic
2.0
8.3
115
676
M54.4
ICD-10 Finland
Lumbago with sciatica
2.1
8.3
89
476
D01
ICPC
Abdominal pain/cramps general
2.4
8.2
65
306
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.2
8.2
74
369
ZXA05
NOMESCO Finland
Left side
2.2
8.0
79
408
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
7.9
85
453
Z71.8
ICD-10 Finland
Other specified counselling
1.9
7.9
150
976
UJF32
NOMESCO Finland
Coloscopy
2.1
7.8
88
479
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
7.8
58
266
XLA10, ,
NOMESCO Finland
3.0
7.8
35
124
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
4.7
7.7
18
40
N06AX11
ATC
mirtazapine; oral
1.9
7.7
145
939
N05AA02
ATC
levomepromazine; systemic
4.1
7.7
21
53
M79.1
ICD-10 Finland
Myalgia
2.1
7.7
81
429
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.1
7.5
79
417
SPAT1283
SPAT
Restricted health certificate
1.9
7.5
114
687
XF404
NOMESCO Finland
Ambulatory ECG
3.1
7.5
32
110
R60.0
ICD-10 Finland
Localized oedema
2.6
7.4
45
187
H02AB06
ATC
prednisolone; systemic
1.8
7.4
182
1277
N05BA04
ATC
oxazepam; oral
1.9
7.4
118
724
N06AX26
ATC
vortioxetine; oral
2.6
7.4
46
194
D24
ICD-10 Finland
Benign neoplasm of breast
6.5
7.3
18
29
A02BC05
ATC
esomeprazole; systemic
1.8
7.3
159
1074
R03AC02
ATC
salbutamol; inhalant
1.8
7.2
244
1874
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
7.2
93
529
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
7.2
140
912
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
6.2
7.2
18
30
G44.2
ICD-10 Finland
Tension-type headache
2.1
7.2
81
440
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.8
7.1
37
142
O20.0
ICD-10 Finland
Threatened abortion
3.4
7.1
26
81
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.5
7.1
45
191
A02BC02
ATC
pantoprazole; systemic
1.8
7.1
253
1971
M79.7
ICD-10 Finland
Fibromyalgia
3.3
7.0
27
87
J01MA02
ATC
ciprofloxacin; systemic
1.8
6.9
131
847
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
6.9
47
207
P99
ICPC
Psychological disorders other
3.8
6.8
21
58
A05
ICPC
Feeling ill
2.8
6.8
36
139
J01DA01
ATC
[U] cefalexin
1.8
6.8
258
2036
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.3
6.7
55
263
J01DB01
ATC
cefalexin; oral
2.2
6.7
334
2871
F61.0
ICD-10 Finland
Mixed personality disorders
4.3
6.6
17
41
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
2.0
6.6
76
415
XQ800
NOMESCO Finland
Prick test
2.4
6.6
45
198
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.5
6.5
41
173
SPAT1240
SPAT
Therapeutic discussion
2.1
6.5
67
350
N03AX09
ATC
lamotrigine; oral
2.7
6.5
36
143
N02BE01
ATC
paracetamol; systemic, rectal
2.4
6.4
348
3051
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
6.4
171
1213
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.8
6.4
32
120
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.4
6.4
46
207
N71.9
ICD-10 Finland
Inflammatory disease of uterus, unspecified
8.4
6.4
13
16
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
6.4
30
109
P03
ICPC
Feeling depressed
2.1
6.3
64
332
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
9.5
6.3
12
13
SPAT1324
SPAT
Screening procedure
1.8
6.3
130
856
N64.4
ICD-10 Finland
Mastodynia
3.2
6.3
25
82
E0000UV, ,
ATC
1.7
6.3
175
1255
R52.9
ICD-10 Finland
Pain, unspecified
2.5
6.3
42
183
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
6.3
81
460
G02CB04
ATC
quinagolide; oral
+∞
6.3
6
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
2.2
6.3
58
291
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.8
6.2
31
117
R53
ICD-10 Finland
Malaise and fatigue
1.8
6.1
106
662
N02AX02
ATC
tramadol; systemic, rectal
1.7
6.1
144
984
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
6.1
133
890
M03BX02
ATC
tizanidine; oral
1.7
6.1
265
2141
R06.0
ICD-10 Finland
Dyspnoea
1.9
6.0
94
568
SAA02
NOMESCO Finland
Basic examination of mouth
1.8
6.0
298
2493
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.0
6.0
74
413

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
95
244
4.83
35.34
2.3
1.6
619.18
292.40
mu/l
0.54
88
221
47
69
7.61
31.27
2.4
1.3
—
—
—
0
0
24
16
15.90
15.08
1.5
1.6
—
—
—
0
0
154
880
2.24
12.85
3.2
2.2
53.37
56.49
u/l
0.42
138
817
306
2378
2.36
10.91
4.3
3.7
8.61
9.62
mm/h
1.30
295
2211
228
1608
2.01
10.14
4.0
3.9
6.17
6.35
mmol/l
0.61
214
1436
210
1458
1.96
9.57
5.5
5.1
8.91
9.24
umol/l
0.40
200
1375
167
1079
1.96
9.34
3.3
3.0
28.20
27.34
u/l
0.22
158
1037
189
1292
1.90
8.77
5.0
5.5
1.21
1.22
mmol/l
1.37
170
1093
124
736
2.01
8.75
2.2
1.9
94.39
135.16
u/l
2.42
119
698
67
318
2.34
8.32
1.6
1.4
—
—
—
0
0
114
668
2.00
8.27
1.5
1.3
17.45
28.57
iu/ml
1.12
44
233
363
3175
3.22
8.12
13.3
9.8
139.50
139.61
mmol/l
0.43
357
3091
291
2326
2.00
8.05
7.7
6.3
69.04
73.35
u/l
1.77
274
2188
333
2801
2.33
8.02
5.9
4.4
14.38
14.28
pmol/l
0.31
321
2623
363
3184
3.17
7.90
13.6
9.9
3.88
3.90
mmol/l
0.53
357
3087
64
305
2.32
7.86
2.2
2.1
370.35
365.52
nmol/l
0.09
57
284
161
1075
1.85
7.80
3.4
4.2
37.20
36.89
g/l
0.37
154
1017
168
1140
1.84
7.70
4.4
4.9
1.21
1.22
mmol/l
2.20
159
1049
37
137
2.88
7.59
1.2
1.2
13.59
12.65
u/l
0.12
29
111
223
1654
1.82
7.58
6.8
5.4
1.97
2.04
e9/l
0.30
203
1501
215
1588
1.79
7.31
7.1
5.4
0.04
0.04
e9/l
0.92
188
1401
113
686
1.91
7.28
4.6
3.2
1.02
1.02
kg/l
0.31
25
95
214
1585
1.78
7.14
7.1
5.4
0.52
0.52
e9/l
0.12
188
1402
141
924
1.83
7.12
2.9
2.3
—
—
—
0
0
240
1847
1.78
6.94
11.4
8.0
4.03
3.95
e9/l
0.29
208
1617
84
480
1.96
6.39
2.1
2.2
76.92
100.22
ug/g
0.54
70
382
219
1668
1.72
6.32
7.3
5.7
0.19
0.18
e9/l
0.53
197
1487
194
1430
1.71
6.31
7.5
5.4
0.67
0.67
%
0.02
181
1333
202
1507
1.71
6.27
7.2
5.7
—
—
—
0
0
192
1414
1.71
6.24
2.2
1.9
—
—
—
0
0
282
2311
1.81
6.22
3.6
2.7
34.67
35.43
u/l
0.10
268
2210
42
185
2.42
6.13
2.2
1.2
—
—
—
0
0
136
919
1.74
5.99
3.0
3.0
2.34
2.35
mmol/l
0.31
123
838
86
506
1.90
5.98
2.5
2.4
474.61
532.98
mosm/kgh2o
1.69
70
437
204
1549
1.67
5.75
7.6
5.2
56.82
56.67
%
0.07
192
1462
62
331
2.04
5.68
3.2
2.1
6986.69
3576.43
u/l
0.26
14
140
205
1562
1.66
5.67
7.8
5.4
29.37
29.52
%
0.08
191
1477
247
1977
1.69
5.64
3.3
2.8
—
—
—
0
0
105
673
1.77
5.50
1.4
1.3
3.75
12.13
u/ml
1.90
35
288
86
525
1.82
5.28
1.5
1.4
613.33
588.93
titre
0.03
18
112
195
1488
1.62
5.21
7.6
5.3
2.76
2.70
%
0.14
182
1398
42
199
2.25
5.21
4.3
2.3
—
—
—
0
0
196
1498
1.62
5.20
7.7
5.6
7.89
7.83
%
0.14
183
1411
274
2281
1.68
5.12
5.2
3.8
—
—
—
0
0
140
987
1.65
5.12
9.4
7.3
1.12
1.07
inr
0.39
40
330
107
709
1.70
4.92
3.7
3.1
—
—
—
0
0
232
1865
1.61
4.87
3.2
2.9
65.07
62.96
ug/l
0.16
224
1758
114
772
1.68
4.82
1.6
1.3
1.93
2.12
g/l
0.83
64
491
85
536
1.75
4.64
3.3
3.4
—
—
—
0
0
207
1633
1.57
4.61
5.6
4.3
0.00
0.00
estimate
0.50
34
330
114
780
1.65
4.61
3.3
3.7
7.40
7.40
ph
0.16
16
147
40
202
2.09
4.25
3.1
1.4
—
—
—
0
0
31
142
2.29
4.18
3.1
1.6
—
—
—
0
0
205
1637
1.53
4.17
4.2
3.1
0.00
0.00
estimate
-0.00
36
348
351
3200
2.02
4.09
6.8
5.0
1.60
2.10
mu/l
0.75
343
3031
206
1651
1.53
4.09
4.2
3.1
0.00
0.01
estimate
0.50
35
323
14
42
3.42
4.08
1.1
1.2
—
—
—
0
0
55
317
1.86
4.02
2.0
2.4
5.29
5.01
umol/l
0.07
43
264
361
3334
2.19
3.91
14.7
9.9
14.54
18.59
mg/l
2.55
294
2510
53
306
1.85
3.86
1.3
1.1
—
—
—
0
0
39
203
2.02
3.84
3.2
1.4
—
—
—
0
0
22
90
2.53
3.79
4.0
1.6
—
—
—
0
0
84
557
1.65
3.77
1.9
2.4
7.49
9.43
e6/l
0.42
75
495
39
205
2.00
3.74
3.2
1.4
—
—
—
0
0
12
29
4.24
3.73
1.2
1.9
—
—
—
0
0
43
235
1.93
3.70
1.2
1.2
—
—
—
0
0
125
916
1.54
3.67
1.4
1.3
2.05
2.12
u/ml
0.02
29
263
14
40
3.59
3.64
1.1
1.3
—
—
nmol/l
—
0
0
138
1036
1.52
3.61
2.1
1.8
96.64
99.09
pmol/l
0.26
78
556
35
180
2.04
3.57
1.4
1.3
—
—
—
0
0
110
788
1.55
3.56
8.7
6.1
—
—
—
0
0
18
69
2.69
3.52
2.3
2.6
—
—
—
0
0
59
363
1.74
3.48
1.3
1.3
23.34
26.50
iu/l
0.31
49
317
131
979
1.51
3.48
2.3
1.9
—
—
—
0
0
25
114
2.28
3.43
2.9
2.4
—
—
—
0
0
36
190
1.99
3.42
3.4
1.4
—
—
—
0
0
37
199
1.95
3.34
3.3
1.4
—
—
—
0
0
369
3470
2.29
3.26
11.3
8.3
24.65
23.69
u/l
0.41
364
3369
19
80
2.45
3.11
1.1
1.1
6.37
6.13
u/ml
0.02
13
38
18
74
2.50
3.09
1.1
1.1
6.35
0.81
u/ml
—
10
31
119
892
1.48
3.06
3.2
2.7
11.02
16.84
ng/l
2.00
51
412
59
377
1.67
3.04
2.7
2.3
5.02
4.66
e6/l
0.10
31
183
31
164
1.97
2.95
3.3
1.4
—
—
—
0
0
75
513
1.57
2.94
1.6
1.5
—
—
—
0
0
27
136
2.06
2.93
1.8
1.6
—
—
—
0
0
20
89
2.31
2.92
1.4
1.3
306.20
369.42
mg/l
1.36
20
81
171
1383
1.42
2.91
2.8
2.2
74.00
74.89
nmol/l
0.15
161
1283
53
333
1.69
2.91
2.0
1.9
—
—
—
0
0
6
9
6.75
2.87
3.8
1.7
11.40
17.03
umol/l
—
6
9
43
257
1.76
2.82
2.3
2.1
29.29
33.51
u/l
0.40
34
211
373
3545
2.35
2.81
14.1
9.2
—
—
—
0
0
65
435
1.59
2.79
2.1
2.4
2.42
2.42
mmol/l
0.02
58
382
305
2754
1.50
2.74
5.1
4.3
37.22
37.89
mmol/mol
0.72
292
2595
107
802
1.46
2.72
2.8
2.7
15.92
71.08
e6/l
1.91
88
584
59
390
1.60
2.67
1.2
1.1
—
—
—
0
0
331
3047
1.59
2.67
4.3
3.5
5.61
5.63
mmol/l
0.08
320
2853
174
1428
1.40
2.66
8.7
7.5
0.00
0.00
e9/l
0.99
146
1175
100
744
1.46
2.63
2.8
2.5
—
—
—
0
0
63
425
1.58
2.62
4.1
2.9
362.03
400.36
ng/l
0.03
33
226
98
729
1.46
2.58
2.7
2.5
0.19
0.29
e6/l
0.55
81
526
53
345
1.62
2.55
1.3
1.3
—
—
—
0
0
19
89
2.19
2.49
1.2
1.3
305.56
316.44
ug/g
—
9
52
112
860
1.43
2.48
4.3
3.4
0.00
0.01
estimate
0.80
35
333
6
12
5.06
2.41
1.2
1.1
—
—
—
0
0
35
209
1.74
2.33
3.3
3.2
—
—
—
0
0
19
92
2.12
2.31
1.1
1.2
0.19
2.69
u/ml
—
10
50
16
72
2.27
2.31
1.9
1.9
—
—
—
0
0
35
210
1.73
2.29
1.3
1.3
231.50
257.92
miu/ml
0.19
12
105
59
408
1.53
2.21
1.8
1.6
1125.91
1116.03
nmol/l
0.03
50
315
48
317
1.59
2.19
1.4
1.3
—
—
—
0
0
99
767
1.39
2.05
2.3
2.0
2.64
2.69
mg/l
0.10
92
655
55
385
1.50
1.95
1.3
1.2
194.71
174.73
iu/ml
0.12
16
158
6
16
3.79
1.94
2.5
3.9
—
—
—
0
0
159
1337
1.32
1.92
3.7
2.8
5.89
5.85
ph
—
9
119
20
108
1.90
1.85
1.2
1.2
—
—
—
0
0
30
184
1.68
1.85
2.7
3.8
60.32
77.35
ng/l
1.28
22
165
42
281
1.55
1.84
3.6
3.7
4.58
4.64
pmol/l
0.19
36
253
19
102
1.91
1.79
3.5
4.9
—
—
—
0
0
94
739
1.36
1.77
2.1
1.6
0.70
0.79
mg/l
0.28
75
538
12
54
2.26
1.75
2.9
2.2
—
—
—
0
0
27
165
1.68
1.70
1.1
1.1
—
—
—
0
0
24
142
1.74
1.69
1.1
1.2
—
—
—
0
0
86
675
1.35
1.63
2.0
2.4
292.73
5852.80
umol/l
3.00
79
619
36
241
1.54
1.59
2.6
4.0
0.00
0.98
%
—
5
70
11
50
2.24
1.58
4.5
3.0
—
—
—
0
0
125
1041
1.30
1.57
3.8
3.1
64.44
58.44
e6/l
0.06
91
650
22
131
1.72
1.53
1.7
1.9
4.47
5.59
iu/l
—
7
51
5
15
3.36
1.53
2.4
1.9
—
—
—
0
0
383
3752
2.61
1.52
23.1
15.0
39.89
39.70
%
0.30
362
3584
20
117
1.75
1.48
1.5
1.2
—
—
—
0
0
14
73
1.95
1.45
1.4
1.3
—
—
—
0
0
383
3758
2.49
1.39
23.5
15.1
133.80
132.98
g/l
0.84
383
3726
6
23
2.63
1.37
2.0
2.0
—
—
—
0
0
176
1552
1.25
1.34
2.7
2.3
—
—
—
0
0
16
91
1.79
1.31
8.1
6.2
—
—
—
0
0
82
662
1.30
1.29
3.4
2.8
—
—
—
0
0
27
181
1.53
1.22
2.6
3.2
—
—
—
0
0
8
37
2.19
1.22
1.4
1.3
—
—
—
0
0
8
38
2.13
1.19
1.3
1.2
—
—
—
0
0
34
242
1.44
1.16
1.4
1.3
—
25.35
—
0
17
5
20
2.52
1.15
1.4
3.6
—
—
—
0
0
69
553
1.30
1.15
1.5
1.5
440.36
46584296.24
pmol/l
1.07
61
483
12
65
1.87
1.14
4.1
5.7
1.08
1.19
mmol/l
0.30
12
57
20
304
0.64
1.14
3.7
3.3
—
—
—
0
0
5
21
2.40
1.09
1.2
1.7
—
—
—
0
0
18
113
1.62
1.07
1.5
1.8
—
—
—
0
0
33
238
1.42
1.07
4.7
2.2
3.79
5.48
e9/l
0.70
27
217
12
67
1.82
1.06
3.0
4.7
—
—
—
0
0
113
978
1.22
0.98
3.6
2.7
—
—
—
0
0
5
23
2.19
0.98
1.0
1.3
1.97
1.87
mmol/l
—
5
23
6
27
2.24
0.94
1.7
1.9
—
—
—
0
0
16
102
1.59
0.92
2.6
2.1
—
—
—
0
0
32
237
1.38
0.91
4.6
5.9
104.44
104.73
mmol/l
0.20
32
237
88
748
1.23
0.91
3.9
3.0
8.15
7.51
mmol/l
0.43
79
657
6
30
2.02
0.87
1.5
1.5
—
—
—
0
0
18
121
1.51
0.84
3.2
5.3
25.96
24.71
mmol/l
0.63
18
121
315
3022
1.23
0.82
3.6
3.2
1.28
1.21
mmol/l
1.06
298
2850
6
32
1.89
0.82
1.3
1.1
150.83
191.72
mg/l
—
6
25
125
1113
1.18
0.79
2.0
2.0
—
—
—
0
0
15
98
1.55
0.79
5.0
8.4
—
—
—
0
0
6
33
1.83
0.79
1.8
1.1
33.50
25.44
mg/l
—
6
23
43
342
1.29
0.79
2.3
2.4
25.05
22.84
%
0.44
35
297
32
244
1.34
0.78
3.6
3.3
—
—
—
0
0
70
591
1.23
0.78
1.5
1.4
20.18
22.03
nmol/l
0.52
64
512
28
209
1.37
0.78
1.5
1.2
—
—
—
0
0
27
202
1.36
0.75
1.0
1.1
—
—
—
0
0
5
24
2.10
0.75
1.2
1.3
1.39
1.62
g/l
—
5
24
49
400
1.26
0.74
1.2
1.2
—
—
—
0
0
7
38
1.86
0.74
7.4
3.8
30.91
24.79
mu/l
—
7
38
7
40
1.76
0.71
1.1
1.1
—
—
—
0
0
5
26
1.93
0.71
1.0
1.1
—
—
—
0
0
28
213
1.34
0.71
5.2
6.7
15.94
13.35
kpa
0.65
28
206
28
213
1.34
0.71
5.2
6.7
5.10
5.10
kpa
0.00
28
205
7
42
1.68
0.68
1.3
2.8
4.99
5.01
kpa
—
7
42
7
42
1.68
0.68
1.3
2.8
8.34
9.34
kpa
—
7
42
14
94
1.51
0.67
1.6
3.7
0.63
0.36
g/l
—
6
35
14
94
1.51
0.67
1.1
1.2
—
—
—
0
0
5
28
1.80
0.66
1.0
1.1
—
—
—
0
0
10
62
1.63
0.65
1.2
1.1
—
—
—
0
0
327
3168
1.20
0.65
4.1
3.6
4.80
4.86
mmol/l
0.63
317
3015
43
352
1.25
0.65
1.3
1.3
—
—
—
0
0
5
29
1.73
0.64
2.6
1.6
—
—
—
0
0
17
121
1.42
0.63
2.7
1.9
—
—
—
0
0
26
201
1.31
0.60
3.8
4.0
18.85
7.44
ug/l
0.32
19
153
329
3199
1.19
0.56
4.3
3.8
2.92
2.90
mmol/l
0.16
320
3026
8
55
1.46
0.56
3.5
4.1
3.76
3.76
mmol/l
—
8
55
6
39
1.55
0.53
1.5
2.0
—
—
—
0
0
27
215
1.27
0.52
5.1
6.7
1.88
1.11
mmol/l
0.58
17
166
41
483
0.83
0.50
1.3
1.3
—
—
—
0
0
28
227
1.25
0.48
1.3
1.4
—
—
—
0
0
19
146
1.32
0.48
3.9
2.6
76.56
75.93
e9/l
—
10
103
50
576
0.85
0.48
1.7
1.4
—
—
—
0
0
5
81
0.61
0.46
6.0
2.7
1.39
1.42
mg/l
—
5
73
7
49
1.44
0.46
2.1
1.2
—
—
—
0
0
102
932
1.13
0.45
1.7
1.7
—
—
—
0
0
28
229
1.24
0.45
1.9
2.4
0.24
0.23
g/l
0.55
22
220
39
332
1.19
0.44
1.4
1.4
—
—
—
0
0
10
70
1.44
0.42
1.2
1.2
—
—
—
0
0
5
33
1.52
0.41
1.6
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
4.85
—
0
11
0
17
0.00
0.40
0.0
1.3
—
28.88
—
0
17
58
515
1.15
0.40
1.9
2.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
5
35
1.43
0.39
1.4
2.5
—
—
—
0
0
5
35
1.43
0.39
3.0
2.0
—
—
—
0
0
19
236
0.80
0.39
1.4
1.4
—
—
—
0
0
9
66
1.37
0.38
3.2
4.1
1.30
1.36
mmol/l
—
9
66
5
37
1.36
0.37
1.0
1.6
20.84
8.18
u/ml
—
5
37
14
108
1.31
0.36
1.0
1.1
—
—
—
0
0
126
1341
0.91
0.35
2.2
2.3
—
—
—
0
0
6
43
1.40
0.35
1.2
1.3
—
—
—
0
0
105
1125
0.91
0.34
1.7
1.7
—
—
—
0
0
20
242
0.82
0.34
1.4
1.5
—
—
—
0
0
15
119
1.27
0.32
1.3
1.6
0.24
0.38
nmol/l
—
9
102
7
96
0.72
0.31
1.0
1.1
—
—
—
0
0
7
96
0.72
0.31
1.0
1.1
—
—
—
0
0
19
157
1.22
0.30
5.9
7.4
—
—
—
0
0
321
3154
1.10
0.28
4.0
3.6
1.49
1.56
mmol/l
2.16
311
2988
20
234
0.85
0.25
1.4
1.4
—
—
—
0
0
5
38
1.32
0.23
1.6
1.3
—
—
—
0
0
15
125
1.21
0.22
2.3
3.4
4.75
5.11
kpa
1.01
15
119
5
40
1.25
0.22
1.6
4.4
—
60.64
—
0
16
0
11
0.00
0.21
0.0
3.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
2.4
—
—
—
0
0
33
365
0.90
0.21
1.7
1.6
—
—
—
0
0
82
774
1.08
0.20
1.9
1.7
1.71
1.36
mmol/l
1.73
74
678
10
80
1.26
0.20
1.7
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
6
51
1.18
0.19
1.0
1.0
—
—
—
0
0
81
767
1.07
0.19
1.6
1.7
—
—
—
0
0
6
53
1.13
0.19
1.0
1.1
—
—
—
0
0
13
145
0.89
0.09
1.5
1.7
—
—
—
0
0
6
54
1.11
0.09
1.5
1.4
—
—
—
0
0
30
318
0.94
0.08
1.4
1.4
—
—
—
0
0
5
62
0.80
0.08
1.0
1.0
—
—
—
0
0
8
92
0.87
0.07
3.0
3.5
—
—
—
0
0
13
119
1.10
0.06
7.5
8.3
92.92
94.76
%
0.60
13
119
64
646
0.99
0.00
4.2
3.9
10.97
9.11
mg/mmol
0.10
37
404
12
122
0.98
0.00
1.0
1.3
2.92
2.86
ug/l
0.02
12
110
12
119
1.01
0.00
8.0
8.2
2.22
1.25
%
0.71
12
119
62
623
0.99
0.00
3.7
3.3
36.58
163.22
mg/l
0.56
37
406
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.40
—
0
6
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
64
0.94
-0.00
2.2
3.2
5.10
4.42
e9/l
—
6
64
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
-0.00
2.5
3.6
57.83
57.82
%
—
6
65
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
1.0
1.5
—
—
—
0
0
12
120
1.00
-0.00
8.0
8.2
0.73
0.64
%
0.38
12
120
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
1.18
—
0
8
7
73
0.96
-0.00
2.4
1.8
13.43
13.30
%
—
7
73
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
5
54
0.92
-0.00
1.0
1.5
—
30.10
—
0
5
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_GALACTORRHEA and mortality.

Females

Parameter HR [95% CI] p-value
N14_GALACTORRHEA 1.223 [0.94, 1.58] 0.127
Birth year 0.998 [0.99, 1.01] 0.625

During the follow-up period (1.1.1998 — 31.12.2019), 61 out of 1805 females with N14_GALACTORRHEA died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_GALACTORRHEA.

N-year risk Females Males
1 0.156% No data
5 0.657% No data
10 1.85% No data
15 3.8% No data
20 6.645% No data

Relationships between endpoints

Index endpoint: N14_GALACTORRHEA – Galactorrhea

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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