Thoracic root disorders

G6_THROOT

peripheral nervous system disease: A disease involving the peripheral nervous system.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — G54.3 Hospital discharge: ICD-9 — 3533 Cause of death: ICD-10 — G54.3 Cause of death: ICD-9 — 3533 2 out of 7 registries used, show all original rules.	66
4. Check minimum number of events None	66
5. Include endpoints None	66
6. Filter based on genotype QC (FinnGen only)	66

Control definitions (FinnGen only)

Control exclude: G6_NERPLEX

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: G54
Name in latin: Morbositates radicum nervorum thoracicorum non alibi classificatae

NAME	G6_THROOT
CONTROL_EXCLUDE	G6_NERPLEX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G543
HD_ICD_9	3533
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G543
COD_ICD_9	3533
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Thoracic root disorders based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	501	279	218
Only index persons	448	254	194
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	52.51	54.30	50.10
Only index persons	51.22	52.91	49.02

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	66	39	27
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	51.00	49.17	53.64

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
60: Matched controls
599

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

G54.3

ICD-10 Finland

Thoracic root disorders, not elsewhere classified

+∞

74.2

N03AX16

ATC

pregabalin; oral

7.1

10.3

N03AX12

ATC

gabapentin; oral

6.8

8.4

M79.2

ICD-10 Finland

Neuralgia and neuritis, unspecified

29.4

7.9

G54.0

ICD-10 Finland

Brachial plexus disorders

90.9

7.6

N06AA09

ATC

amitriptyline; systemic

8.0

7.5

R60.0

ICD-10 Finland

Localized oedema

8.7

7.1

R29.8

ICD-10 Finland

Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems

19.6

7.0

N02AX02

ATC

tramadol; systemic, rectal

4.4

6.8

178

N06AX21

ATC

duloxetine; oral

6.3

6.6

M54.5

ICD-10 Finland

Low back pain

4.2

6.3

122

M54.9

ICD-10 Finland

Dorsalgia, unspecified

6.6

6.3

G56.0

ICD-10 Finland

Carpal tunnel syndrome

17.3

6.1

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

184

3.30

5.38

2.3

2.0

92.7

95.7

pmol/l

0.16

(42870588) Differential panel, method unspecified - Blood

152

2.96

4.43

5.3

5.2

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

3.47

4.17

1.8

2.3

2.4

g/l

0.03

(3022948) Iron [Moles/volume] in Serum or Plasma

3.38

4.16

1.9

2.3

10.0

14.7

umol/l

1.50

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

3.15

3.89

3.2

1.9

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

3.37

3.64

3.5

1.7

—

(3022096) Basophils/100 leukocytes in Blood

226

2.61

3.54

6.3

5.3

0.7

0.6

0.24

215

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

3.30

3.53

3.7

1.8

—

(3018010) Neutrophils/100 leukocytes in Blood

235

2.61

3.53

6.2

5.4

58.7

58.0

0.16

226

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

263

2.64

3.50

8.2

6.2

9.9

10.2

umol/l

0.13

243

(3002030) Lymphocytes/100 leukocytes in Blood

236

2.60

3.49

6.5

5.5

25.5

27.2

0.39

226

(3032080) INR in Blood by Coagulation assay

185

2.57

3.45

9.1

8.8

1.1

1.2

inr

0.43

(3006504) Eosinophils/100 leukocytes in Blood

231

2.52

3.31

6.2

5.5

2.6

0.00

221

(3019069) Monocytes/100 leukocytes in Blood

232

2.50

3.27

6.5

5.7

9.1

8.4

0.78

224

(3012544) pH of Venous blood

3.47

2.96

3.4

3.6

—

(3013707) Erythrocyte sedimentation rate by Westergren method

367

2.71

2.96

5.4

3.7

14.9

11.9

mm/h

0.52

337

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

5.88

2.95

1.7

2.2

—

(3031040) Bacteria [#/volume] in Urine by Automated count

322

2.41

2.73

4.6

—

1424.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

228

2.27

2.69

6.7

4.8

—

(3005719) IgG [Mass/volume] in Serum or Plasma

3.10

2.51

2.5

4.0

8.7

10.6

g/l

1.26

(3023368) Bacteria identified in Blood by Culture

116

2.34

2.49

5.0

4.6

—

(3019060) Gas panel - Arterial blood

3.43

2.33

14.9

5.9

—

(3037522) Nuclear Ab [Titer] in Serum

2.60

2.26

1.2

1.4

—

373.3

—

(3007164) IgA [Mass/volume] in Serum or Plasma

2.34

2.22

1.4

1.6

2.6

3.2

g/l

0.48

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

115

2.21

2.15

3.4

1.8

2.8

3.2

mg/l

0.73

100

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

5.31

2.11

2.2

2.5

365.4

248.3

ug/l

—

(3044889) 12 lead EKG panel

374

2.20

2.07

4.6

3.7

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

3.43

1.94

19.4

11.0

—

(36660697) Celiac disease serology panel - Serum

3.11

1.93

1.3

1.1

—

(3012516) Albumin [Mass/volume] in Urine

120

2.10

1.91

3.1

2.8

2629.5

73.1

mg/l

0.47

(3028026) IgM [Mass/volume] in Serum or Plasma

2.81

1.88

1.3

1.7

1.2

1.1

g/l

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

2.29

1.88

5.1

2.7

0.8

mmol/l

0.09

(3030467) Casts [#/volume] in Urine by Automated count

121

2.08

1.87

2.8

2.6

1.7

0.2

e6/l

0.48

(36304419) Bacteria [Presence] in Urine

121

2.08

1.87

2.2

2.6

—

(3035350) Ketones [Presence] in Urine by Test strip

243

1.94

1.85

3.8

3.7

0.0

estimate

—

(3037467) Urinalysis macro (dipstick) panel - Urine

334

1.95

1.74

5.3

4.5

—

(3009261) Glucose [Presence] in Urine by Test strip

247

1.89

1.72

3.8

0.0

estimate

—

(3044640) Blood type and Crossmatch panel - Blood

151

1.93

1.66

2.5

2.6

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.89

1.63

2.6

1.8

—

(3021601) Nitrite [Presence] in Urine by Test strip

241

1.85

1.63

4.8

0.0

estimate

—

(40761535) Cells panel - Urine sediment

2.62

1.60

5.4

3.8

—

(3020682) Albumin/Creatinine [Ratio] in Urine

130

1.90

1.51

4.5

3.7

4.4

11.1

mg/mmol

0.96

(40768443) Skin Pathology biopsy report

2.76

1.40

1.3

1.1

—

(3000330) Specific gravity of Urine by Test strip

2.76

1.40

1.7

3.8

—

(3026008) Bacteria identified in Urine by Culture

150

1.82

1.40

2.3

3.3

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

3.09

1.38

1.0

3.7

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

101

1.92

1.36

3.7

3.8

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.64

1.33

1.2

1.3

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

161

1.77

1.32

2.8

3.0

—

(40758558) Short blood count panel - Blood

127

1.82

1.31

9.9

7.0

—

(3015736) pH of Urine

188

1.74

1.31

3.3

3.4

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

2.92

1.31

4.0

13.3

25.0

24.6

mmol/l

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.00

1.18

2.0

2.6

0.3

3.3

e6/l

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.62

1.17

2.8

2.4

0.7

0.8

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

527

2.13

1.15

25.3

13.2

25.6

23.5

mg/l

0.13

405

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.97

1.13

2.0

2.5

1.2

1.0

e6/l

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.49

1.11

2.8

2.5

1.0

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

1.85

1.08

1.4

1.2

10.7

3.4

u/ml

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

1.80

1.01

1.5

1.2

15.7

23.3

iu/ml

—

(40768797) Stomach Pathology biopsy report

1.87

1.00

1.0

1.2

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

209

1.59

1.00

4.7

2.4

100.1

115.3

ug/l

0.29

191

(3002582) Erythrocytes [#/volume] in Urine

137

1.66

0.99

2.9

25.1

39.5

e6/l

0.32

111

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.88

0.99

1.4

2.6

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.96

0.98

1.3

1.7

—

(3000991) Gas panel - Venous blood

2.10

0.89

5.2

8.1

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.84

0.86

1.3

2.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

108

1.64

0.83

3.0

2.0

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

1.77

0.81

1.8

1.5

1.4

1.3

0.25

(3022313) Gas panel - Capillary blood

0.00

0.81

0.0

1.6

—

(40768804) Tissue Pathology biopsy report

208

1.50

0.81

2.0

1.9

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

541

1.85

0.77

28.9

14.9

4.0

mmol/l

0.19

529

(40760892) CBC W Ordered Manual Differential panel - Blood

128

1.56

0.76

4.8

4.0

—

(4034850)

2.17

0.76

15.6

9.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

155

1.52

0.76

3.0

3.2

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.08

0.74

1.2

1.5

—

(3018095) Leukocytes [#/volume] in Urine

166

1.49

0.71

3.7

3.2

33.3

37.5

e6/l

0.07

125

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.92

0.70

1.2

1.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

205

1.44

0.67

4.0

3.8

—

(3042936) Bacteria identified in Isolate by Culture

1.66

0.67

6.7

2.1

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.72

0.65

2.6

4.6

2.2

2.1

—

(3025941) Bacteria identified in Stool by Culture

1.78

0.65

1.0

1.1

—

(3029937) Albumin [Presence] in Urine by Test strip

142

1.47

0.64

4.6

4.1

0.0

estimate

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.72

0.62

1.0

3.7

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

537

1.66

0.62

29.2

14.9

139.8

139.7

mmol/l

0.23

525

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

0.00

0.61

0.0

1.8

—

24.2

—

(3022621) pH of Urine by Test strip

1.78

0.59

1.3

2.1

—

(3000494) Fungus identified in Specimen by Culture

1.61

0.58

4.1

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.61

0.58

1.7

1.8

—

(3003694) ABO and Rh group [Type] in Blood

138

1.42

0.53

1.3

1.4

—

(1761868) Lipid panel - Serum or Plasma

217

0.71

0.53

3.2

2.7

—

(4010399)

1.61

0.43

1.4

1.5

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.43

0.39

1.6

—

(4035726)

1.51

0.37

1.0

1.3

—

(3013512) EKG study

138

1.31

0.35

3.7

3.6

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

205

1.27

0.34

3.7

43.7

41.5

ng/l

0.03

121

(3020564) Creatinine [Moles/volume] in Serum or Plasma

562

1.47

0.33

28.1

14.7

76.2

77.8

umol/l

0.20

562

(40761511) CBC panel - Blood by Automated count

555

1.37

0.32

27.3

12.5

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

0.74

0.24

1.9

2.0

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

569

1.35

0.24

14.6

9.4

26.1

25.6

u/l

0.07

555

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.21

0.0

1.1

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.3

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.21

0.0

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

343

1.18

0.21

2.7

3.2

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

0.21

0.0

2.1

—

110.1

—

(4094501)

0.00

0.21

0.0

1.0

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

0.20

0.0

1.4

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.20

0.0

1.4

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

0.00

0.20

0.0

1.2

—

1.8

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

489

1.19

0.17

15.4

12.4

81.9

80.9

ml/min/173m2

0.10

399

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.15

0.10

1.6

2.1

3.8

6.5

ug/l

—

(40761536) Microorganisms panel - Urine sediment

1.12

0.10

6.2

3.9

—

(3002256) Pathology report gross observation

1.12

0.09

1.0

1.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.09

0.08

1.0

1.6

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.86

0.07

2.1

1.5

—

(3009542) Hematocrit [Volume Fraction] of Blood

481

1.07

0.03

28.4

14.1

39.9

40.0

0.02

381

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

145

0.96

0.00

4.0

4.5

1.3

4.4

ug/l

0.85

139

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.6

—

(3016038) Potassium [Moles/volume] in Urine

0.00

0.0

1.0

—

27.4

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.8

—

(3000012) Reticulocyte production index

0.00

0.0

1.6

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

2.2

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

3.2

—

(3000492) Spirometry study

0.90

0.00

1.2

1.3

—

(3007461) Platelets [#/volume] in Blood

589

1.02

0.00

38.1

19.0

260.5

247.5

e9/l

0.85

579

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.96

0.00

4.0

3.4

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

0.88

0.00

2.2

1.3

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

2.6

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3035941) MCH [Entitic mass]

589

1.02

0.00

37.8

19.0

30.2

30.3

0.21

584

(3026725) Estradiol (E2) [Moles/volume] in Serum or Plasma

0.00

0.0

1.7

—

0.3

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

14.7

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.5

—

89.8

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

5.2

—

40.6

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

1.0

—

32.8

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.92

0.00

3.0

1.5

568.8

403.2

nmol/l

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.0

1.7

—

1.2

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.0

2.2

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.1

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.1

—

(3024731) MCV [Entitic volume]

590

1.00

0.00

37.9

18.9

91.3

91.1

0.15

585

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

1.3

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.84

0.00

1.2

1.5

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

2.4

—

(3000963) Hemoglobin [Mass/volume] in Blood

591

0.98

0.00

38.2

19.1

132.3

135.5

g/l

0.75

586

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

2.3

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.3

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

2.0

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

2.2

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.5

—

(3012441) Differential panel - Pleural fluid

0.00

0.0

1.9

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.5

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.0

1.3

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint G6_THROOT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have G6_THROOT.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: G6_THROOT – Thoracic root disorders

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Thoracic root disorders

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints