Relapsing fevers

AB1_RELAP_FEVER_WIDE

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Primary healthcare outpatient: ICD-10 — A68 Hospital discharge: ICD-10 — A68 Hospital discharge: ICD-9 — 08[7] Hospital discharge: ICD-8 — 08[8] Cause of death: ICD-10 — A68 Cause of death: ICD-9 — 08[7] Cause of death: ICD-8 — 08[8] 3 out of 7 registries used, show all original rules.	94
4. Check minimum number of events None	94
5. Include endpoints None	94
6. Filter based on genotype QC (FinnGen only)	91

Control definitions (FinnGen only)

Control exclude: AB1_OTHER_SPIROCHAETAL

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF13

NAME	AB1_RELAP_FEVER_WIDE
CONTROL_EXCLUDE	AB1_OTHER_SPIROCHAETAL
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD	A68
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	A68
HD_ICD_9	08[7]
HD_ICD_8	08[8]
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	A68
COD_ICD_9	08[7]
COD_ICD_8	08[8]
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Relapsing fevers based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Relapsing fevers

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	91	50	41
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	32.29	23.31	43.23

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
94: Matched controls
940

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

A68.9

ICD-10 Finland

Relapsing fever, unspecified

+∞

65.4

R50.9

ICD-10 Finland

Fever, unspecified

8.5

24.4

103

0879X

ICD-9 Finland

Relapsing fever, unspecified

+∞

24.0

EMB10

NOMESCO Finland

Tonsillectomy

7.9

8.8

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

3.4

7.0

135

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40760892) CBC W Ordered Manual Differential panel - Blood

343

2.80

5.53

7.8

6.1

—

(3028026) IgM [Mass/volume] in Serum or Plasma

4.18

5.47

1.3

1.4

1.24

1.23

g/l

0.02

(3005322) IgE [Units/volume] in Serum or Plasma

3.18

3.93

1.2

79.35

533.70

u/ml

0.55

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

111

2.42

3.05

1.4

1.3

19.72

32.59

iu/ml

—

(3003327) Ova and parasites identified in Stool by Light microscopy

3.75

3.01

1.0

1.4

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

10.45

3.01

1.0

1.8

6.90

12.92

u/l

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

109

2.33

2.74

1.3

0.90

8.61

u/ml

—

(3023368) Bacteria identified in Blood by Culture

155

2.15

2.68

5.2

4.1

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

5.74

2.58

1.2

1.5

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

2.51

2.3

20.80

24.33

0.58

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

6.52

2.40

1.4

1.5

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

6.52

2.40

1.8

1.6

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

4.85

2.31

1.0

—

(40768797) Stomach Pathology biopsy report

2.37

2.24

1.3

1.2

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

3.54

2.23

1.3

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

3.89

2.19

1.6

1.8

—

(3013707) Erythrocyte sedimentation rate by Westergren method

528

1.94

2.18

6.7

4.0

12.94

9.50

mm/h

1.05

498

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

136

2.03

2.13

2.3

2.0

1.28

0.91

mg/l

0.38

113

(4062490) Immunoglobulin typing, IgG

5.21

2.09

1.0

1.1

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

5.21

2.09

1.4

1.7

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

196

1.87

2.00

2.6

3.8

18.46

34.13

ng/l

0.71

118

(3045424) Erythrocytes [Presence] in Urine

4.73

1.96

1.6

1.1

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

1.95

0.0

1.6

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

3.35

1.92

1.0

1.1

—

18.74

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

225

1.80

1.89

4.6

3.2

—

(3027945) Reticulocytes/100 erythrocytes in Blood

2.28

1.87

4.0

3.0

1.33

1.70

1.16

(3022217) INR in Platelet poor plasma by Coagulation assay

268

1.70

1.66

4.4

10.8

1.02

1.23

inr

2.49

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

225

1.72

1.62

1.9

1.8

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

109

1.93

1.62

2.2

1.9

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

2.82

1.61

1.0

1.5

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.62

1.48

1.3

2.4

—

(3042936) Bacteria identified in Isolate by Culture

1.99

1.46

2.8

2.4

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.94

1.44

2.5

2.3

13.38

13.71

umol/l

0.07

(3004588) Protein electrophoresis panel - Serum or Plasma

2.52

1.42

1.4

2.6

—

(3035350) Ketones [Presence] in Urine by Test strip

344

1.59

1.38

5.4

3.4

0.00

estimate

—

(3019832) Treponema pallidum Ab [Presence] in Serum

123

1.80

1.38

1.8

1.6

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.26

1.38

1.8

1.4

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

200

1.65

1.34

5.4

2.7

55.55

51.68

u/l

0.33

189

(3021601) Nitrite [Presence] in Urine by Test strip

337

1.57

1.33

7.2

4.5

0.00

estimate

—

(3025941) Bacteria identified in Stool by Culture

2.15

1.31

1.3

1.1

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.87

1.30

1.6

2.3

—

(3013512) EKG study

142

1.72

1.29

2.9

3.7

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

611

1.66

1.28

4.5

3.7

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

265

1.58

1.28

5.9

3.3

—

(40758558) Short blood count panel - Blood

185

1.64

1.28

8.0

6.5

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.33

1.28

1.0

1.7

—

(3009508) Creatinine [Moles/volume] in Urine

204

1.61

1.24

4.6

2.8

6.94

8.35

mmol/l

1.09

188

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.39

1.20

1.0

1.1

—

(3009261) Glucose [Presence] in Urine by Test strip

343

1.53

1.20

5.4

3.4

0.00

estimate

—

(3041096) Erythrocytes [Presence] in Urine by Automated

189

1.60

1.17

5.0

2.9

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

2.58

1.16

1.2

1.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

207

1.58

1.16

2.1

1.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

463

1.52

1.14

6.6

3.9

—

(3018095) Leukocytes [#/volume] in Urine

235

1.55

1.13

3.8

3.5

42.49

31.17

e6/l

0.17

167

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

730

1.79

1.13

18.8

12.3

21.58

21.23

mg/l

0.04

555

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

2.46

1.10

4.0

3.8

3.04

3.30

g/l

—

(3008898) HLA-B27 [Presence]

2.10

1.08

1.0

1.1

—

(36304419) Bacteria [Presence] in Urine

184

1.57

1.07

3.6

2.9

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

2.34

1.04

1.4

1.9

—

(3000991) Gas panel - Venous blood

1.95

1.01

10.0

12.4

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

0.99

0.0

1.5

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.30

0.95

1.3

2.3

—

(3045414) Leukocytes [Presence] in Urine

2.22

0.93

2.2

1.5

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.14

0.91

6.0

32.7

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.67

0.91

2.7

2.5

3.63

4.49

e6/l

—

(3002582) Erythrocytes [#/volume] in Urine

200

1.49

0.90

3.6

3.0

11.34

371.01

e6/l

0.60

159

(3000494) Fungus identified in Specimen by Culture

1.74

0.86

1.7

1.8

—

(3012516) Albumin [Mass/volume] in Urine

149

1.53

0.85

5.7

3.2

51.91

448.45

mg/l

0.49

102

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

554

1.42

0.80

4.0

3.5

14.37

14.61

pmol/l

0.31

512

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

223

1.43

0.80

2.4

1.9

97.86

89.65

pmol/l

0.62

133

(3030467) Casts [#/volume] in Urine by Automated count

178

1.47

0.79

3.5

2.9

0.01

0.36

e6/l

2.77

137

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.24

0.77

1.4

1.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

2.24

0.77

1.6

1.4

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

2.14

0.76

3.8

2.6

42.02

52.25

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

2.14

0.76

1.4

1.9

—

(40761536) Microorganisms panel - Urine sediment

1.61

0.72

6.1

3.1

—

(40761535) Cells panel - Urine sediment

1.72

0.72

3.3

3.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.69

0.68

1.4

1.5

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.57

0.67

6.5

1.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

157

1.43

0.67

7.9

3.6

7.03

6.58

mg/mmol

0.03

107

(3022621) pH of Urine by Test strip

1.64

0.66

2.4

1.8

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

122

1.48

0.66

2.8

3.8

16.27

22.09

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

1.76

0.64

3.8

84.40

94.31

—

(3033658) Prothrombin time (PT) actual/Normal

158

1.42

0.64

5.3

3.9

97.33

91.56

0.69

158

(3019060) Gas panel - Arterial blood

1.76

0.59

2.7

17.1

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

293

1.31

0.56

3.1

2.5

78.05

70.60

nmol/l

1.05

267

(3003396) Base excess in Arterial blood by calculation

1.53

0.56

7.0

17.8

1.30

1.40

mmol/l

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

109

1.45

0.55

8.6

3.6

33.67

447.93

ng/l

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.57

0.54

1.0

1.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.53

0.53

2.5

1.5

—

(3029937) Albumin [Presence] in Urine by Test strip

194

1.32

0.48

6.9

3.5

0.00

0.02

estimate

—

(3022313) Gas panel - Capillary blood

1.43

0.46

4.9

6.8

—

(4200892) Spirometry reversibility

1.43

0.46

1.3

1.4

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.43

0.46

1.9

1.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

122

1.38

0.46

1.8

1.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.46

0.45

2.6

1.6

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

105

1.39

0.44

2.8

2.5

0.34

0.85

e6/l

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.41

0.0

1.5

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.41

0.0

1.6

—

(3017044) Thyrotropin receptor Ab [Units/volume] in Serum

0.00

0.40

0.0

1.9

—

5.18

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

112

0.69

0.40

1.4

1.6

1.66

1.39

—

101

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.36

0.39

8.3

2.1

30.56

32.78

u/l

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

222

1.24

0.34

1.6

1.3

2.33

1.64

u/ml

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

147

1.28

0.34

2.3

2.4

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

101

1.33

0.34

7.8

7.4

1.12

1.16

mmol/l

0.22

(3044640) Blood type and Crossmatch panel - Blood

204

1.24

0.33

2.3

—

(3019225) pH of Specimen

1.40

0.32

8.7

4.5

—

(3023323) Follitropin [Units/volume] in Serum or Plasma

1.37

0.32

1.0

1.7

22.86

20.07

iu/l

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

499

1.19

0.32

4.3

3.0

52.74

36.66

u/l

0.52

475

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.32

0.31

4.0

3.9

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

159

1.24

0.30

1.7

1.6

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.25

0.28

9.4

7.3

103.88

104.42

mmol/l

—

(3022145) Colonoscopy Study observation

1.25

0.28

1.1

1.3

—

(36660697) Celiac disease serology panel - Serum

1.30

0.28

1.8

1.1

—

(3021589) Normoblasts [#/volume] in Blood

345

1.17

0.26

10.2

7.9

0.00

e9/l

0.50

270

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

181

1.21

0.25

2.2

2.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

307

1.17

0.25

3.0

2.7

—

(3007164) IgA [Mass/volume] in Serum or Plasma

201

1.19

0.24

1.6

1.3

2.40

2.01

g/l

0.51

113

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

1.37

0.24

1.2

1.6

—

(3026008) Bacteria identified in Urine by Culture

183

1.19

0.23

3.5

2.6

—

(3050129) First trimester maternal screen panel - Serum or Plasma

1.20

0.22

1.2

1.3

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

10.9

—

941.50

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

19.3

—

1965.00

—

(3009542) Hematocrit [Volume Fraction] of Blood

830

1.25

0.21

24.8

17.6

39.11

40.43

0.92

788

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.1

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.21

0.0

1.1

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.21

0.0

2.2

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.5

—

(3011288) Drugs identified in Urine by Screen method

1.19

0.20

1.0

1.7

—

(3044889) 12 lead EKG panel

431

1.13

0.19

3.6

3.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

129

1.19

0.18

1.3

1.4

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.18

0.18

6.7

7.2

25.31

24.45

mmol/l

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.16

0.18

1.1

1.4

—

(3016879) Cocaine [Presence] in Urine

0.76

0.17

1.0

1.5

—

(3027944) Amphetamines [Presence] in Urine

0.76

0.17

1.0

1.5

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.23

0.16

2.4

1.8

—

(1761868) Lipid panel - Serum or Plasma

257

1.13

0.15

2.4

2.2

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.17

0.10

1.2

1.1

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.04

0.08

1.2

1.1

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.04

0.08

1.8

1.6

—

(40768804) Tissue Pathology biopsy report

265

1.08

0.08

2.2

1.9

—

(3002256) Pathology report gross observation

1.09

0.08

1.4

1.2

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.85

0.07

1.4

1.6

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

167

1.10

0.07

2.2

2.1

—

(3002385) Erythrocyte distribution width [Ratio]

667

1.07

0.06

18.3

14.2

14.67

14.47

0.10

657

(21494755) Public health laboratory ask at order entry panel

1.11

0.04

1.6

1.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

162

1.06

0.02

5.3

3.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

104

1.07

0.01

1.6

1.5

—

(3003694) ABO and Rh group [Type] in Blood

208

1.01

0.00

1.9

1.6

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

628

1.01

0.00

13.8

10.6

85.60

90.63

ml/min/173m2

1.12

484

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

107

1.03

0.00

2.3

1.8

—

(40761511) CBC panel - Blood by Automated count

769

1.01

0.00

16.5

10.1

—

(3028300) Cannabinoids [Presence] in Urine

0.89

0.00

1.0

1.5

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

1.2

—

32.20

—

(3000764) Benzodiazepines [Presence] in Urine

0.90

-0.00

1.0

1.5

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.2

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

-0.00

0.0

1.0

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

-0.00

0.0

7.0

—

64.80

—

(3002079) Sodium [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.0

—

182.11

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.3

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

-0.00

0.0

6.2

—

(40768800) Prostate Pathology biopsy report

0.00

-0.00

0.0

1.3

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

6.6

—

12.24

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

113.67

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3027008) Opiates [Presence] in Urine

0.90

-0.00

1.0

1.5

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

-0.00

0.0

1.4

—

32.76

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.1

—

61.63

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.1

—

7.16

—

(4035726) Immunohistochemistry procedure

0.98

-0.00

2.6

1.4

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

1127.40

—

(3012441) Differential panel - Pleural fluid

0.00

-0.00

0.0

1.3

—

(3013727) Leukocytes other/100 leukocytes in Blood

0.00

-0.00

0.0

6.2

—

56.50

—

(3024928) Oxygen saturation in Venous blood

0.00

-0.00

0.0

7.7

—

(3022493) Free Hemoglobin [Mass/volume] in Plasma

0.00

-0.00

0.0

1.4

—

91.00

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.2

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

1.7

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

6.8

—

0.57

—

(3000492) Spirometry study

0.87

-0.00

1.7

1.4

—

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

0.09

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

1.7

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

1.9

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.97

-0.00

9.5

8.8

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.4

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

4.1

—

17.08

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.89

-0.00

1.0

1.5

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.2

—

12.60

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

17.19

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.3

—

196.86

—

(37021550) Renin [Units/volume] in Plasma --upright

0.00

-0.00

0.0

1.6

—

199.12

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.92

-0.00

1.6

1.4

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

2.2

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

3.30

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.96

-0.00

2.3

2.0

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.5

—

(3036180) Methadone [Presence] in Urine

0.00

-0.00

0.0

2.6

—

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: AB1_RELAP_FEVER_WIDE – Relapsing fevers

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Relapsing fevers

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Relapsing fevers (AB1_RELAP_FEVER_WIDE)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints