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Secondary malignant neoplasm of respiratory and digestive organs

DOID Endpoint Browser

C3_SECONDARY_RESPIRATORY_DIGESTIVE

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C78
  • Cause of death: ICD-8 — 197
  • Cancer registry: Topography ICD-O-3 — C78
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

437

4. Check minimum number of events

None

437

5. Include endpoints

None

437

6. Filter based on genotype QC (FinnGen only)

437

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Similar endpoints

↥

List of similar endpoints to Secondary malignant neoplasm of respiratory and digestive organs based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 437 174 263
Unadjusted period prevalence (%) 0.09 0.06 0.12
Median age at first event (years) 74.11 74.43 73.90

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
325
Matched controls
3251
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
108.3
174.5
183
38
130
Kela drug reimbursment
Malignant tumour
17.4
94.8
168
188
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
54.9
84.9
100
26
N02AA05
ATC
oxycodone; systemic
11.5
82.5
193
365
Z51.5
ICD-10 Finland
Palliative care
16.9
80.7
140
139
A03FA01
ATC
metoclopramide; systemic, rectal
10.7
77.2
188
370
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
109.5
71.6
76
9
H02AB02
ATC
dexamethasone; systemic
13.3
68.7
133
161
A04AA02
ATC
granisetron; systemic, transdermal
16.4
58.0
98
83
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
18.2
52.9
85
62
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
17.6
48.8
79
58
JN4BD
NOMESCO Finland
Extensive body CT
6.9
39.9
114
235
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
5.0
39.2
175
614
L01BC06
ATC
capecitabine; oral
16.9
36.4
59
42
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
27.3
31.4
43
18
TPX10
NOMESCO Finland
Implantation of vascular injection port
17.3
30.7
49
33
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
8.1
30.5
73
112
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
12.2
28.5
53
51
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
20.0
26.0
39
22
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
+∞
23.2
22
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
24.3
22.2
31
14
JN4CD
NOMESCO Finland
Very extensive body CT
7.5
20.8
51
79
8000/3-C80.9
ICD-O-3
Neoplasm, malignant of unknown primary site
61.6
20.2
23
*
A04AA01
ATC
ondansetron; systemic, rectal
6.8
20.1
53
91
WF049
NOMESCO Finland
Radiotherapy of metastasis
8.3
19.8
45
62
C80.0
ICD-10 Finland
Malignant neoplasm, primary site unknown, so stated
212.3
19.8
20
*
WZC30
NOMESCO Finland
Teaching
4.0
17.3
77
235
C80
ICD-10 Finland
Malignant neoplasm, without specification of site
53.0
17.2
20
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
67.0
16.9
19
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
10.9
15.8
30
30
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
10.9
15.3
29
29
XX3DW
NOMESCO Finland
Time consuming IT work
4.2
15.2
62
174
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
+∞
14.7
14
*
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
13.4
14.6
25
20
C80.9
ICD-10 Finland
Malignant neoplasm, primary site unspecified
156.7
14.6
15
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
6.3
13.8
37
65
A98
ICPC
Health maint/preventive medicine
0.4
13.7
178
2450
WW500
NOMESCO Finland
Blood transfusion
6.6
13.6
35
58
A06AH03
ATC
naloxegol; oral
22.3
13.5
19
9
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
8.6
12.6
27
34
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.6
12.5
61
198
C26.9
ICD-10 Finland
Malignant neoplasm: Ill-defined sites within the digestive system
135.0
12.5
13
*
R18
ICD-10 Finland
Ascites
12.3
12.5
22
19
A09AA02
ATC
multienzymes (lipase, protease etc.)
11.2
12.5
23
22
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.2
12.3
72
267
A04AD12
ATC
aprepitant; systemic
13.1
12.3
21
17
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.0
11.8
49
139
369
Kela drug reimbursment
Regorafenib
+∞
11.5
11
*
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
26.1
11.2
15
6
R83
ICPC
Respiratory infection other
0.0
11.2
*
263
8010/3-C80.9
ICD-O-3
Carcinoma, NOS, of unknown primary site
62.1
10.7
12
*
8140/3-C80.9
ICD-O-3
Adenocarcinoma, NOS, of unknown primary site
113.5
10.5
11
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
19.6
10.4
15
8
UJK02
NOMESCO Finland
ERCP
6.5
10.2
26
43
8140/3-C25.9
ICD-O-3
Adenocarcinoma, NOS, of pancreas, NOS
15.2
10.1
16
11
C20
ICD-10 Finland
Malignant neoplasm of rectum
15.2
10.1
16
11
J01MA12
ATC
levofloxacin; systemic
2.5
10.1
90
428
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
12.7
10.0
17
14
K83.1
ICD-10 Finland
Obstruction of bile duct
10.0
9.9
19
20
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
6.2
9.9
26
45
B01AB05
ATC
enoxaparin; parenteral
2.2
9.8
122
685
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.7
9.7
32
73
176
Kela drug reimbursment
Regorafenib
+∞
9.4
9
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
9.2
63
257
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
10.5
9.1
17
17
8000/3-C25.9
ICD-O-3
Neoplasm, malignant of pancreas, NOS
19.3
9.0
13
7
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
11.1
8.9
16
15
TJA10
NOMESCO Finland
Laparocentesis
28.4
8.5
11
*
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
28.4
8.5
11
*
JAH00
NOMESCO Finland
Laparotomy
5.0
8.5
26
55
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.9
8.4
34
95
L01BC59
ATC
trifluridine, combinations; systemic
+∞
8.4
8
*
L01XE21
ATC
[U] regorafenib; oral
+∞
8.4
8
*
JN4AD
NOMESCO Finland
Body CT examination
3.2
8.2
43
148
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
8.1
168
1140
D70.82
ICD-10 Finland
Drug-induced neutropenia
10.4
8.1
15
15
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
8.1
8.0
17
22
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
5.1
7.9
24
50
C76.2
ICD-10 Finland
Malignant neoplasm of other and ill-defined sites: Abdomen
81.9
7.4
8
*
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
13.8
7.4
12
9
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
11.2
7.4
13
12
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
+∞
7.3
7
*
B01AB10
ATC
tinzaparin; parenteral
3.4
7.3
34
107
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
6.8
7.2
17
26
J94.8
ICD-10 Finland
Other specified pleural conditions
6.6
7.0
17
27
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
6.6
7.0
17
27
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
7.0
80
423
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
8.5
6.9
14
17
C80.99
ICD-10 Finland
Malignant tumor without specified localization or histology
40.9
6.8
8
*
JLC30
NOMESCO Finland
Pancreatoduodenectomy
17.1
6.8
10
6
L03AA13
ATC
pegfilgrastim; parenteral
4.8
6.7
21
46
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
0.0
6.7
*
164
JDE00
NOMESCO Finland
Gastrojejunostomy
23.1
6.7
9
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.5
6.7
30
92
A04AA55
ATC
palonosetron, combinations; systemic
9.0
6.6
13
15
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
5.2
6.6
19
38
L82
ICD-10 Finland
Seborrhoeic keratosis
0.2
6.5
8
331
A02BC02
ATC
pantoprazole; systemic
1.8
6.5
213
1647
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.4
6.4
22
53
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
5.0
6.3
19
40
C18.0
ICD-10 Finland
Malignant neoplasm: Caecum
18.4
6.3
9
5
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
6.0
6.2
16
28
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
10.3
6.1
11
11
ZX070
NOMESCO Finland
Intensity modified radiotherapy
6.2
6.1
15
25
WF003
NOMESCO Finland
Adjuvant radiotherapy
4.5
6.0
20
47

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
215
425
8.99
117.19
5.5
4.3
117.4
42.7
ug/l
1.03
203
359
84
182
5.48
38.01
2.8
3.3
11145.4
7583.2
u/ml
0.14
74
156
32
25
13.73
33.50
1.0
1.2
—
—
—
0
0
234
1133
3.29
33.23
5.0
4.4
—
—
—
0
0
230
1110
3.26
32.71
3.5
2.4
48.6
56.8
u/l
2.16
223
1031
319
1889
3.55
31.70
15.7
6.3
19.9
12.2
umol/l
2.78
311
1794
104
315
4.02
30.56
1.4
1.4
—
—
—
0
0
76
185
4.76
29.69
1.7
2.0
3.5
3.1
ug/l
0.05
70
162
8
872
0.07
28.59
1.4
1.6
1.0
1.3
mmol/l
—
8
708
278
1627
2.95
25.99
8.8
10.9
1.3
1.4
inr
0.35
76
432
98
351
3.31
21.83
1.9
2.1
0.2
0.2
g/l
6.71
93
326
263
1620
2.57
20.20
6.0
4.7
28.4
34.7
g/l
35.29
252
1496
231
3227
0.40
19.66
3.1
5.4
2.5
2.6
mmol/l
0.50
187
2906
22
24
9.60
18.35
5.0
3.5
196.5
84.0
u/ml
0.46
22
24
219
3080
0.42
17.46
6.5
6.5
44.1
41.1
mmol/mol
3.46
184
2824
197
1119
2.38
17.28
2.9
2.6
—
—
—
0
0
227
3113
0.44
15.97
3.2
4.7
1.3
1.4
mmol/l
4.41
186
2808
230
3135
0.44
15.82
3.0
4.8
4.4
4.4
mmol/l
0.39
188
2856
279
1909
2.28
14.97
18.5
8.7
4.9
4.3
e9/l
2.61
271
1654
238
1584
2.10
12.97
6.3
4.3
—
—
—
0
0
217
2946
0.48
12.89
3.6
4.6
2.3
2.0
mu/l
1.40
185
2604
225
3014
0.48
12.80
3.1
4.2
1.4
1.3
mmol/l
2.54
183
2700
33
83
4.22
12.15
1.2
2.9
39.7
31.8
umol/l
0.68
24
67
81
360
2.53
11.66
4.5
4.4
—
—
—
0
0
83
1566
0.42
11.65
1.6
2.1
90.5
93.1
pmol/l
0.21
48
803
167
2415
0.50
10.87
3.8
4.4
—
—
—
0
0
221
1530
1.90
9.79
3.6
4.2
34.2
63.8
ng/l
0.77
183
1185
27
70
4.05
9.55
1.8
3.8
2.1
0.9
%
1.82
22
58
27
72
3.93
9.20
3.3
2.9
—
—
—
0
0
332
2663
2.03
9.06
17.3
7.7
182.3
79.8
u/l
16.09
324
2477
101
560
2.05
8.41
2.0
2.0
—
—
—
0
0
37
129
3.04
8.39
3.8
5.4
—
—
—
0
0
16
30
5.50
8.26
1.1
1.2
—
—
—
0
0
171
1145
1.81
7.98
4.3
4.4
—
—
—
0
0
40
903
0.39
7.96
1.8
3.1
0.9
0.8
ug/l
0.31
25
624
261
3180
0.55
7.94
3.4
5.1
6.4
6.1
mmol/l
1.95
217
2845
85
1437
0.49
7.93
17.8
10.3
0.0
0.0
e9/l
0.56
76
1166
21
53
4.11
7.70
1.3
1.4
—
—
—
0
0
28
87
3.37
7.66
2.5
4.7
2.4
2.8
mmol/l
0.47
20
53
248
1875
1.75
7.44
6.9
6.8
1.2
1.2
mmol/l
0.05
187
1582
273
2130
1.75
7.23
5.2
5.0
7.3
6.9
mmol/l
2.53
265
1998
180
2395
0.58
7.15
3.1
3.6
15.4
15.0
pmol/l
0.87
155
2103
27
87
3.24
6.99
1.3
1.4
241.3
269.8
ug/g
0.26
16
51
20
53
3.91
6.88
1.3
1.3
64871.7
40944.7
e6/l
0.37
15
29
10
14
7.29
6.72
1.1
1.1
—
—
—
0
0
136
895
1.75
6.48
4.7
3.9
—
—
—
0
0
66
1120
0.52
5.82
2.5
3.1
7.1
7.2
mmol/l
0.09
49
910
18
50
3.71
5.82
1.4
4.5
—
—
—
0
0
222
1711
1.60
5.55
5.9
5.9
1.2
1.2
mmol/l
0.18
200
1532
55
286
2.06
5.36
5.1
6.2
25.0
24.4
mmol/l
0.47
49
270
244
1934
1.59
5.34
3.9
3.2
214.7
52.2
u/l
12.23
222
1776
0
135
0.00
5.34
0.0
1.9
—
—
—
0
0
13
30
4.44
5.33
1.5
1.2
—
—
—
0
0
103
659
1.74
5.30
3.5
4.9
—
—
—
0
0
57
305
2.00
5.14
4.0
4.3
—
—
—
0
0
70
1125
0.55
5.02
2.2
2.1
145.1
291.5
u/l
1.24
64
1050
18
56
3.31
4.95
4.2
2.6
4.6
4.5
e9/l
0.02
18
56
69
1109
0.55
4.94
2.5
3.2
54.0
283.7
mg/l
1.34
43
733
17
51
3.43
4.93
5.7
3.1
81.1
36.9
u/ml
0.99
17
51
204
1579
1.55
4.77
4.4
5.7
20.3
26.1
%
9.38
187
1449
201
1552
1.55
4.74
4.3
5.8
9.1
8.9
%
0.11
186
1433
18
60
3.09
4.45
4.9
3.0
63.7
59.3
%
0.53
18
60
235
2790
0.66
4.39
26.5
18.6
29.7
38.9
%
6.13
90
1732
154
1138
1.55
4.35
3.5
5.2
—
—
—
0
0
198
1546
1.51
4.32
4.0
5.4
2.1
2.8
%
4.06
182
1423
51
281
1.92
4.24
3.4
4.4
—
—
—
0
0
29
128
2.36
4.23
6.0
6.6
1.8
1.4
mmol/l
0.55
23
114
17
58
3.01
4.05
1.5
1.7
—
—
—
0
0
38
193
2.06
3.96
3.2
3.8
—
—
—
0
0
192
1509
1.49
3.96
4.0
5.4
0.6
0.6
%
0.74
176
1393
112
790
1.56
3.82
1.4
1.3
—
—
—
0
0
47
262
1.89
3.78
3.1
3.8
—
7.4
—
0
26
26
529
0.46
3.77
1.1
1.4
2.6
2.7
g/l
0.17
17
305
9
16
5.72
3.67
1.4
4.9
64.6
46.9
%
—
9
16
21
86
2.51
3.60
4.0
4.2
25.0
33.1
mg/l
0.82
16
56
0
91
0.00
3.53
0.0
1.1
—
—
—
0
0
46
759
0.56
3.47
4.2
4.2
—
—
—
0
0
11
306
0.34
3.33
1.8
1.6
—
—
—
0
0
9
249
0.35
3.29
1.1
1.3
—
—
—
0
0
44
253
1.82
3.23
3.2
3.2
117.3
125.5
g/l
1.99
44
248
64
411
1.65
3.20
2.5
2.9
44.8
9.1
umol/l
2.02
53
366
0
82
0.00
3.17
0.0
1.1
—
—
—
0
0
0
82
0.00
3.17
0.0
2.3
—
—
—
0
0
86
1189
0.66
3.08
3.0
4.0
4.3
8.9
mg/mmol
2.67
54
746
7
12
5.91
3.03
1.3
1.5
—
—
—
0
0
190
1551
1.40
2.95
4.3
5.4
63.4
58.4
%
5.41
176
1432
48
292
1.72
2.93
2.0
4.3
1.2
0.9
%
0.43
27
113
64
926
0.64
2.81
2.3
2.9
12945.9
8389.9
umol/l
0.21
49
777
5
6
8.41
2.75
2.2
4.3
115.6
3128.3
u/l
—
5
6
5
167
0.29
2.75
1.4
1.4
—
48.5
—
0
13
41
243
1.76
2.75
3.1
3.1
—
—
—
0
0
6
10
6.07
2.70
1.0
1.0
1.7
2.2
mmol/l
—
6
5
21
101
2.13
2.57
7.0
6.6
106.2
105.1
mmol/l
0.69
16
93
21
101
2.13
2.57
7.0
6.6
10.3
11.7
mmol/l
1.38
16
93
12
44
2.78
2.56
1.8
3.5
66.4
56.3
%
—
5
32
12
283
0.41
2.56
1.1
2.5
—
—
—
0
0
36
584
0.58
2.53
1.0
1.2
0.7
1.5
u/ml
1.30
12
156
7
16
4.43
2.48
1.1
3.3
526.1
73.5
nmol/l
—
7
16
12
45
2.71
2.47
1.2
1.4
—
—
—
0
0
5
161
0.30
2.46
1.4
1.3
—
—
—
0
0
7
193
0.35
2.46
3.0
2.6
—
12.5
—
0
6
18
83
2.22
2.44
1.5
4.1
—
—
—
0
0
10
247
0.39
2.39
1.4
1.5
—
—
—
0
0
264
2321
1.35
2.38
5.0
5.0
703.7
3068.0
e6/l
0.69
20
50
198
1669
1.34
2.37
3.8
5.3
1.4
1.9
e9/l
5.64
181
1458
36
216
1.73
2.34
5.7
4.4
—
—
—
0
0
28
157
1.84
2.27
3.3
3.9
—
—
—
0
0
150
1223
1.34
2.21
4.6
3.4
2.3
2.3
mmol/l
1.53
138
1053
55
374
1.54
2.20
3.0
3.6
—
—
—
0
0
8
25
3.24
2.10
1.4
1.3
—
—
—
0
0
15
298
0.49
2.07
1.2
1.5
—
—
—
0
0
106
1329
0.73
2.06
1.9
2.7
337.5
153.5
ug/l
2.52
94
1199
53
364
1.52
2.03
3.0
3.5
2.6
1.9
mmol/l
1.26
42
281
264
2363
1.30
1.89
5.8
4.7
—
—
—
0
0
191
1642
1.29
1.86
3.6
5.2
0.0
0.0
e9/l
0.43
178
1405
112
903
1.32
1.74
4.3
4.5
0.0
0.0
estimate
0.00
37
287
222
2480
0.79
1.71
2.9
4.2
26.9
14.3
mm/h
8.44
194
2242
0
48
0.00
1.70
0.0
1.2
—
—
—
0
0
195
1695
1.27
1.70
3.7
5.4
0.2
0.2
e9/l
3.46
181
1472
9
190
0.46
1.65
1.1
1.2
—
—
—
0
0
8
174
0.45
1.61
1.4
3.6
22.1
24.0
mmol/l
—
8
155
29
184
1.62
1.59
6.2
5.2
1.5
1.6
%
0.12
24
174
65
489
1.39
1.58
4.2
7.3
2.0
1.3
mmol/l
0.84
47
382
71
910
0.74
1.56
2.8
3.4
—
—
—
0
0
10
205
0.48
1.55
4.0
10.3
23.4
24.6
mmol/l
—
10
192
187
1633
1.25
1.53
3.6
5.2
0.7
0.6
e9/l
3.40
176
1387
0
43
0.00
1.53
0.0
1.1
—
—
—
0
0
0
44
0.00
1.52
0.0
1.4
—
—
—
0
0
27
172
1.61
1.47
1.2
1.3
—
—
—
0
0
6
22
2.75
1.44
3.7
2.4
—
—
—
0
0
136
1581
0.80
1.40
3.8
5.4
7.9
3.6
ug/l
0.67
112
1391
39
274
1.46
1.39
2.0
4.4
0.2
0.2
%
0.35
25
105
59
448
1.37
1.37
4.3
7.6
93.6
95.3
%
0.52
52
432
81
997
0.77
1.33
2.7
3.3
—
—
—
0
0
28
185
1.55
1.33
6.0
5.2
1.0
0.9
%
0.45
23
174
65
824
0.75
1.32
11.8
6.4
—
—
—
0
0
0
41
0.00
1.31
0.0
2.3
—
—
—
0
0
12
62
1.96
1.29
1.6
3.3
—
—
—
0
0
103
858
1.26
1.24
1.5
1.8
413.8
8166626.3
pmol/l
0.50
85
698
18
110
1.66
1.17
2.1
2.6
57.6
89.4
ug/min
—
8
68
0
33
0.00
1.16
0.0
3.7
—
17.9
—
0
27
0
34
0.00
1.16
0.0
1.3
—
—
—
0
0
13
72
1.83
1.16
1.1
1.2
61.5
58.0
mmol/l
—
8
61
52
399
1.34
1.15
4.5
8.1
115.4
120.7
g/l
1.14
47
390
5
111
0.44
1.14
2.0
1.9
22.6
21.0
s
—
5
103
30
210
1.46
1.11
2.6
2.6
—
—
—
0
0
342
3246
1.25
1.11
29.3
17.2
52.0
27.1
mg/l
19.70
332
2654
62
491
1.31
1.11
4.3
7.2
10.6
11.8
kpa
1.20
56
470
62
491
1.31
1.11
4.3
7.2
5.1
5.0
kpa
0.14
56
470
72
585
1.28
1.07
18.6
27.7
1.6
1.3
inr
0.68
12
74
9
157
0.56
1.00
1.0
1.4
—
—
—
0
0
0
29
0.00
0.98
0.0
3.8
—
—
—
0
0
0
29
0.00
0.98
0.0
1.2
—
—
—
0
0
34
254
1.37
0.91
2.1
4.4
1.1
0.5
%
1.15
16
80
29
211
1.40
0.91
4.1
3.1
5.3
4.1
e9/l
1.26
21
154
64
769
0.80
0.86
4.0
3.9
208.6
292.3
ng/l
0.21
51
655
132
1170
1.18
0.86
3.5
3.5
—
—
—
0
0
182
1659
1.17
0.84
4.7
4.2
0.0
0.0
estimate
0.00
45
287
180
1641
1.16
0.83
4.5
4.2
0.0
0.0
estimate
0.00
47
308
86
736
1.21
0.82
4.7
4.7
1.0
1.0
kg/l
0.05
23
111
20
139
1.46
0.80
6.1
3.2
0.1
0.2
g/l
2.96
14
54
52
422
1.26
0.80
2.0
1.7
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
2.1
—
—
—
0
0
0
25
0.00
0.79
0.0
2.1
—
—
—
0
0
0
26
0.00
0.78
0.0
2.1
—
7.0
—
0
18
0
26
0.00
0.78
0.0
1.9
—
9.8
—
0
26
0
27
0.00
0.77
0.0
1.2
—
—
—
0
0
0
27
0.00
0.77
0.0
1.2
—
—
—
0
0
0
28
0.00
0.76
0.0
2.3
—
2.6
—
0
23
6
109
0.54
0.73
2.3
3.6
—
—
—
0
0
13
84
1.56
0.72
2.1
2.6
—
—
—
0
0
57
479
1.22
0.67
3.0
5.5
1.0
1.0
mmol/l
0.09
57
437
28
217
1.31
0.63
6.4
9.9
—
—
—
0
0
8
50
1.61
0.61
1.8
1.9
36.5
32.7
pg
—
8
50
0
20
0.00
0.60
0.0
1.2
—
68.0
—
0
7
6
35
1.72
0.58
2.5
2.7
—
—
—
0
0
141
1293
1.13
0.57
2.0
2.2
—
—
—
0
0
5
87
0.57
0.56
1.0
2.2
7.6
13.4
mg/l
—
5
77
176
1639
1.12
0.56
6.7
5.7
0.0
0.0
estimate
0.00
47
300
9
63
1.44
0.52
1.8
1.3
—
—
—
0
0
13
175
0.73
0.45
1.0
1.2
—
—
—
0
0
6
91
0.65
0.42
1.0
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
3.8
—
29.3
—
0
10
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.5
—
0.9
—
0
18
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
54
478
1.15
0.39
1.8
2.5
1.9
1.8
%
0.41
48
426
345
3526
0.90
0.38
42.6
25.0
7.8
6.9
e9/l
7.68
338
3400
345
3526
0.90
0.38
42.5
25.0
4.0
4.4
e12/l
36.38
339
3399
345
3525
0.90
0.37
42.4
24.9
90.8
91.7
fl
2.11
340
3458
345
3525
0.90
0.37
42.6
25.0
270.0
238.1
e9/l
7.68
340
3418
345
3525
0.90
0.37
42.4
24.9
29.9
30.4
pg
4.53
340
3457
19
234
0.80
0.36
2.5
2.7
11.1
10.3
g/l
0.22
14
212
14
110
1.28
0.32
20.8
11.8
—
—
—
0
0
35
309
1.14
0.28
3.6
3.5
—
—
—
0
0
7
93
0.75
0.22
1.7
4.3
—
—
—
0
0
125
1308
0.94
0.22
3.1
4.0
97.0
108.1
e6/l
0.13
116
960
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
167.0
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
2.7
—
0
13
0
13
0.00
0.21
0.0
1.5
—
29.3
—
0
13
28
313
0.89
0.20
2.3
8.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
6.4
—
25.3
—
0
14
0
14
0.00
0.20
0.0
1.5
—
83.2
—
0
9
5
69
0.72
0.17
1.4
1.3
143.6
142.3
e6/l
—
5
54
5
69
0.72
0.17
1.4
1.2
1.2
18.2
e6/l
—
5
53
329
3333
0.95
0.16
33.0
16.5
—
—
—
0
0
28
255
1.10
0.15
1.9
4.5
0.0
0.1
%
0.78
18
86
79
827
0.95
0.15
1.7
1.8
1541.0
1192.2
nmol/l
1.53
63
617
342
3449
0.96
0.10
30.4
20.6
4.0
4.0
mmol/l
1.07
337
3347
72
746
0.96
0.10
1.4
1.7
2.2
1.4
mg/l
1.22
60
596
339
3418
0.96
0.09
19.1
11.1
34.0
24.8
u/l
5.27
328
3274
120
1172
1.03
0.09
2.9
3.5
108.4
118.3
e6/l
0.05
114
909
45
469
0.95
0.07
1.1
1.3
—
—
—
0
0
6
74
0.81
0.07
1.0
1.2
—
—
—
0
0
115
1126
1.03
0.07
5.0
4.1
7.4
7.4
ph
0.13
49
213
342
3442
0.97
0.07
30.5
20.5
137.5
139.6
mmol/l
25.28
337
3341
26
246
1.06
0.06
1.1
1.5
—
—
—
0
0
37
384
0.96
0.05
1.9
2.6
1.9
7.1
ug/l
5.66
26
338
37
383
0.96
0.04
1.2
1.3
—
—
—
0
0
40
410
0.97
0.03
1.8
1.5
—
—
—
0
0
97
978
0.99
0.01
1.8
2.2
4.0
3.3
mg/l
1.69
77
838
25
255
0.98
0.00
1.2
1.4
—
—
—
0
0
18
182
0.99
0.00
3.9
2.9
—
—
—
0
0
132
1322
1.00
0.00
2.4
3.2
1222.2
1764.8
ng/l
1.66
118
1148
43
433
0.99
0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
39.8
—
0
6
0
6
0.00
0.00
0.0
2.2
—
16.4
—
0
6
5
52
0.96
0.00
1.2
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
4.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
8.7
—
—
—
0
0
6
68
0.88
0.00
1.3
1.2
3.5
4.0
mmol/l
—
6
63
5
50
1.00
0.00
1.2
3.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
6
60
1.00
0.00
1.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
0.00
0.0
2.3
—
6.2
—
0
9
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
5.4
—
0.6
—
0
9
0
5
0.00
0.00
0.0
1.2
—
18.7
—
0
5
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_SECONDARY_RESPIRATORY_DIGESTIVE – Secondary malignant neoplasm of respiratory and digestive organs

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).