This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_SECONDARY_RESPIRATORY_DIGESTIVE_EXALLC for full statistics.
Secondary malignant neoplasm of respiratory and digestive organs
C3_SECONDARY_RESPIRATORY_DIGESTIVE
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
437 |
4. Check minimum number of eventsNone |
437 |
5. Include endpointsNone |
437 |
6. Filter based on genotype QC (FinnGen only) |
437 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Secondary malignant neoplasm of respiratory and digestive organs
based on the number of shared cases.
Similar with more cases:
- Secondary uncertain malignant neoplasm
- Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)
- Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 437 | 174 | 263 |
| Unadjusted period prevalence (%) | 0.09 | 0.06 | 0.12 |
| Median age at first event (years) | 74.11 | 74.43 | 73.90 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 325
- Matched controls
- 3251
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
108.3
174.5
183
38
130
Kela drug reimbursment
Malignant tumour
17.4
94.8
168
188
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
54.9
84.9
100
26
N02AA05
ATC
oxycodone; systemic
11.5
82.5
193
365
Z51.5
ICD-10 Finland
Palliative care
16.9
80.7
140
139
A03FA01
ATC
metoclopramide; systemic, rectal
10.7
77.2
188
370
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
109.5
71.6
76
9
H02AB02
ATC
dexamethasone; systemic
13.3
68.7
133
161
A04AA02
ATC
granisetron; systemic, transdermal
16.4
58.0
98
83
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
18.2
52.9
85
62
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
17.6
48.8
79
58
JN4BD
NOMESCO Finland
Extensive body CT
6.9
39.9
114
235
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
5.0
39.2
175
614
L01BC06
ATC
capecitabine; oral
16.9
36.4
59
42
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
27.3
31.4
43
18
TPX10
NOMESCO Finland
Implantation of vascular injection port
17.3
30.7
49
33
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
8.1
30.5
73
112
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
12.2
28.5
53
51
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
20.0
26.0
39
22
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
+∞
23.2
22
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
24.3
22.2
31
14
JN4CD
NOMESCO Finland
Very extensive body CT
7.5
20.8
51
79
8000/3-C80.9
ICD-O-3
Neoplasm, malignant of unknown primary site
61.6
20.2
23
*
A04AA01
ATC
ondansetron; systemic, rectal
6.8
20.1
53
91
WF049
NOMESCO Finland
Radiotherapy of metastasis
8.3
19.8
45
62
C80.0
ICD-10 Finland
Malignant neoplasm, primary site unknown, so stated
212.3
19.8
20
*
WZC30
NOMESCO Finland
Teaching
4.0
17.3
77
235
C80
ICD-10 Finland
Malignant neoplasm, without specification of site
53.0
17.2
20
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
67.0
16.9
19
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
10.9
15.8
30
30
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
10.9
15.3
29
29
XX3DW
NOMESCO Finland
Time consuming IT work
4.2
15.2
62
174
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
+∞
14.7
14
*
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
13.4
14.6
25
20
C80.9
ICD-10 Finland
Malignant neoplasm, primary site unspecified
156.7
14.6
15
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
6.3
13.8
37
65
A98
ICPC
Health maint/preventive medicine
0.4
13.7
178
2450
WW500
NOMESCO Finland
Blood transfusion
6.6
13.6
35
58
A06AH03
ATC
naloxegol; oral
22.3
13.5
19
9
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
8.6
12.6
27
34
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.6
12.5
61
198
C26.9
ICD-10 Finland
Malignant neoplasm: Ill-defined sites within the digestive system
135.0
12.5
13
*
R18
ICD-10 Finland
Ascites
12.3
12.5
22
19
A09AA02
ATC
multienzymes (lipase, protease etc.)
11.2
12.5
23
22
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.2
12.3
72
267
A04AD12
ATC
aprepitant; systemic
13.1
12.3
21
17
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.0
11.8
49
139
369
Kela drug reimbursment
Regorafenib
+∞
11.5
11
*
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
26.1
11.2
15
6
R83
ICPC
Respiratory infection other
0.0
11.2
*
263
8010/3-C80.9
ICD-O-3
Carcinoma, NOS, of unknown primary site
62.1
10.7
12
*
8140/3-C80.9
ICD-O-3
Adenocarcinoma, NOS, of unknown primary site
113.5
10.5
11
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
19.6
10.4
15
8
UJK02
NOMESCO Finland
ERCP
6.5
10.2
26
43
C20
ICD-10 Finland
Malignant neoplasm of rectum
15.2
10.1
16
11
8140/3-C25.9
ICD-O-3
Adenocarcinoma, NOS, of pancreas, NOS
15.2
10.1
16
11
J01MA12
ATC
levofloxacin; systemic
2.5
10.1
90
428
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
12.7
10.0
17
14
K83.1
ICD-10 Finland
Obstruction of bile duct
10.0
9.9
19
20
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
6.2
9.9
26
45
B01AB05
ATC
enoxaparin; parenteral
2.2
9.8
122
685
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.7
9.7
32
73
176
Kela drug reimbursment
Regorafenib
+∞
9.4
9
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
9.2
63
257
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
10.5
9.1
17
17
8000/3-C25.9
ICD-O-3
Neoplasm, malignant of pancreas, NOS
19.3
9.0
13
7
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
11.1
8.9
16
15
TJA10
NOMESCO Finland
Laparocentesis
28.4
8.5
11
*
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
28.4
8.5
11
*
JAH00
NOMESCO Finland
Laparotomy
5.0
8.5
26
55
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.9
8.4
34
95
L01XE21
ATC
[U] regorafenib; oral
+∞
8.4
8
*
L01BC59
ATC
trifluridine, combinations; systemic
+∞
8.4
8
*
JN4AD
NOMESCO Finland
Body CT examination
3.2
8.2
43
148
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
8.1
168
1140
D70.82
ICD-10 Finland
Drug-induced neutropenia
10.4
8.1
15
15
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
8.1
8.0
17
22
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
5.1
7.9
24
50
C76.2
ICD-10 Finland
Malignant neoplasm of other and ill-defined sites: Abdomen
81.9
7.4
8
*
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
13.8
7.4
12
9
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
11.2
7.4
13
12
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
+∞
7.3
7
*
B01AB10
ATC
tinzaparin; parenteral
3.4
7.3
34
107
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
6.8
7.2
17
26
J94.8
ICD-10 Finland
Other specified pleural conditions
6.6
7.0
17
27
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
6.6
7.0
17
27
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
7.0
80
423
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
8.5
6.9
14
17
C80.99
ICD-10 Finland
Malignant tumor without specified localization or histology
40.9
6.8
8
*
JLC30
NOMESCO Finland
Pancreatoduodenectomy
17.1
6.8
10
6
L03AA13
ATC
pegfilgrastim; parenteral
4.8
6.7
21
46
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
0.0
6.7
*
164
JDE00
NOMESCO Finland
Gastrojejunostomy
23.1
6.7
9
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.5
6.7
30
92
A04AA55
ATC
palonosetron, combinations; systemic
9.0
6.6
13
15
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
5.2
6.6
19
38
L82
ICD-10 Finland
Seborrhoeic keratosis
0.2
6.5
8
331
A02BC02
ATC
pantoprazole; systemic
1.8
6.5
213
1647
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.4
6.4
22
53
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
5.0
6.3
19
40
C18.0
ICD-10 Finland
Malignant neoplasm: Caecum
18.4
6.3
9
5
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
6.0
6.2
16
28
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
10.3
6.1
11
11
ZX070
NOMESCO Finland
Intensity modified radiotherapy
6.2
6.1
15
25
WF003
NOMESCO Finland
Adjuvant radiotherapy
4.5
6.0
20
47
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_SECONDARY_RESPIRATORY_DIGESTIVE – Secondary malignant neoplasm of respiratory and digestive organs
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).