No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
438 |
4. Check minimum number of eventsNone |
438 |
5. Include endpointsNone |
438 |
6. Filter based on genotype QC (FinnGen only) |
428 |
Control definitions (FinnGen only)
- Control exclude
- K11_APPENDIX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K35-K38
- Name in latin
- Alii morbi appendicis
Other diseases of appendix
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3360 | 2099 | 1235 |
| Only index persons | 2823 | 1812 | 1011 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.03 |
| Only index persons | 0.06 | 0.07 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 37.74 | 37.44 | 37.89 |
| Only index persons | 33.98 | 34.08 | 33.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 428 | 290 | 138 |
| Unadjusted period prevalence (%) | 0.09 | 0.10 | 0.06 |
| Median age at first event (years) | 38.06 | 36.36 | 41.65 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 438
- Matched controls
- 4380
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K38.9
ICD-10 Finland
Disease of appendix, unspecified
+∞
90.9
84
*
JEA01
NOMESCO Finland
Laparoscopic appendectomy
133.3
82.3
86
8
54301
ICD-8 Finland
Other diseases of appendix, Stercolithium appendicis
+∞
81.9
76
*
K38.8
ICD-10 Finland
Other specified diseases of appendix
+∞
69.7
65
*
54309
ICD-8 Finland
Other diseases of appendix, Unspecified
+∞
57.6
54
*
5439X
ICD-9 Finland
Other diseases of appendix, Other and unspecified diseases of appendix
+∞
45.6
43
*
54308
ICD-8 Finland
Other diseases of appendix, Alii definiti
+∞
44.5
42
*
6421
FHL
Appendicectomy
11.8
43.3
46
43
JEA00
NOMESCO Finland
Appendectomy
10.0
30.4
36
39
K38.1
ICD-10 Finland
Appendicular concretions
+∞
28.4
27
*
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
143.5
25.9
27
*
54300
ICD-8 Finland
Other diseases of appendix, Mucocele appendicis
+∞
18.9
18
*
K35.1
ICD-10 Finland
Acute appendicitis with peritoneal abscess
+∞
15.7
15
*
D37.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Appendix
88.3
15.7
17
*
K38.0
ICD-10 Finland
Hyperplasia of appendix
+∞
13.6
13
*
K37
ICD-10 Finland
Unspecified appendicitis
+∞
12.6
12
*
54003
ICD-8 Finland
Acute appendicitis, Cum abscessu
+∞
12.6
12
*
UJF32
NOMESCO Finland
Coloscopy
2.1
10.7
132
747
C18.11
ICD-10 Finland
Malignant tumor of the appendix invasive carcinoma
112.6
10.5
11
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.6
10.4
64
267
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.2
10.3
108
572
D12.1
ICD-10 Finland
Benign neoplasm: Appendix
26.7
9.9
13
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
9.9
167
1052
JAH01
NOMESCO Finland
Laparoscopy
3.7
9.5
31
89
C18.19
ICD-10 Finland
Malignant tumor in appendix other or unspecified histology
102.2
9.5
10
*
N02AX02
ATC
tramadol; systemic, rectal
1.8
8.9
203
1398
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
8.7
53
220
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
4.6
8.4
20
45
K36
ICD-10 Finland
Other appendicitis
+∞
8.4
8
*
54399, ,
ICD-8 Finland
+∞
7.3
7
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
6.7
130
837
8480/3-C18.1
ICD-O-3
Mucinous adenocarcinoma of appendix
+∞
6.3
6
*
8480/1-C18.1
ICD-O-3
Low grade appendiceal mucinous neoplasm of appendix
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
89
380
2.68
14.05
3.9
4.2
3.69
20.36
ug/l
0.83
70
307
18
38
4.90
8.18
3.6
3.4
2.53
3.64
nmol/l
0.92
18
38
13
20
6.66
5.59
3.2
3.8
57.46
80.70
nmol/l
1.01
13
20
158
1136
1.61
5.18
2.8
2.5
52.23
62.24
u/l
1.32
146
1051
33
142
2.43
5.05
3.9
2.9
702.63
1225.73
u/ml
0.18
27
118
214
1660
1.57
5.03
3.2
2.5
—
—
—
0
0
239
1917
1.54
4.74
7.9
6.2
10.95
10.81
umol/l
0.07
231
1819
42
217
2.03
4.18
2.4
2.4
25.74
67.88
u/ml
1.11
42
208
46
246
1.97
4.16
1.4
1.6
—
—
—
0
0
119
845
1.56
3.96
2.8
2.2
—
—
—
0
0
250
2077
1.47
3.85
6.8
4.3
6.76
6.66
mmol/l
0.25
244
1951
54
320
1.78
3.58
2.2
2.0
379.87
365.70
nmol/l
0.18
48
296
14
46
3.11
3.56
1.4
1.5
—
—
—
0
0
274
2344
1.45
3.45
5.2
4.4
1699.00
3889.70
e6/l
—
7
40
246
2071
1.43
3.33
8.9
8.9
4.18
4.01
e9/l
0.48
222
1814
191
1537
1.43
3.32
5.9
4.4
36.43
35.80
g/l
0.94
176
1426
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
21
90
2.40
3.29
2.8
2.5
0.50
0.36
u/ml
—
9
51
319
2832
1.47
3.13
9.1
7.5
76.82
78.10
u/l
0.26
297
2653
14
51
2.80
3.01
1.4
1.5
—
—
—
0
0
309
2738
1.44
2.97
4.3
4.1
11.88
12.04
mm/h
0.08
287
2514
200
1650
1.39
2.90
15.8
12.9
1.21
1.23
inr
0.17
62
480
172
1384
1.40
2.89
3.6
3.7
31.80
31.56
ng/l
0.01
120
961
212
1790
1.36
2.57
9.9
6.2
1.21
1.22
mmol/l
0.41
182
1527
203
1703
1.36
2.56
6.1
5.6
56.99
57.15
%
0.06
195
1591
26
136
1.97
2.56
1.8
2.0
—
—
—
0
0
46
289
1.66
2.52
1.8
2.5
66.49
67.21
g/l
0.22
40
266
196
1641
1.35
2.48
8.7
5.3
1.21
1.22
mmol/l
0.62
174
1498
204
1725
1.34
2.40
6.5
5.8
27.74
28.00
%
0.13
195
1610
51
337
1.58
2.30
3.7
2.5
69.34
46.64
u/l
0.28
44
276
22
113
2.00
2.29
1.9
1.6
—
200.00
—
0
7
12
47
2.60
2.29
1.3
1.6
—
—
—
0
0
102
791
1.38
2.06
1.2
1.2
2.54
1.79
u/ml
0.17
23
220
14
63
2.26
2.03
1.4
1.5
—
—
—
0
0
73
537
1.43
1.99
3.6
2.8
4.70
2.91
e6/l
0.39
38
278
205
1768
1.30
1.98
3.9
3.8
0.00
0.00
estimate
0.50
42
370
77
575
1.41
1.94
3.5
2.6
1.09
1.03
e6/l
0.06
42
313
8
28
2.89
1.87
1.9
1.3
—
—
—
0
0
6
17
3.56
1.84
1.7
1.4
—
—
—
0
0
309
2830
1.31
1.83
4.2
4.0
14.82
14.73
pmol/l
0.24
280
2568
204
1777
1.28
1.77
3.9
3.7
0.00
0.01
estimate
0.50
42
328
180
1548
1.28
1.72
2.7
2.2
77.75
77.76
nmol/l
0.00
160
1372
203
1773
1.27
1.70
5.4
5.0
0.00
0.00
estimate
0.50
41
349
12
55
2.22
1.69
1.0
1.3
—
—
—
0
0
7
25
2.83
1.65
1.0
1.1
18.70
17.84
u/l
—
7
25
7
25
2.83
1.65
1.0
1.1
93.79
71.28
u/l
—
7
25
28
174
1.65
1.65
3.1
2.8
0.09
0.21
e6/l
1.06
28
169
40
272
1.52
1.63
5.0
3.6
77.17
82.12
ng/l
0.18
35
244
5
14
3.60
1.62
2.2
2.9
31440.00
35193.21
ug/l
—
5
14
5
14
3.60
1.62
1.8
1.3
—
—
—
0
0
14
70
2.03
1.61
1.6
1.8
—
—
—
0
0
117
961
1.30
1.58
3.8
4.1
0.00
0.01
estimate
0.88
40
343
31
201
1.58
1.56
1.5
1.7
—
—
—
0
0
86
678
1.33
1.56
4.4
3.9
213.23
306.16
ng/l
0.27
61
530
117
964
1.29
1.54
3.8
2.9
0.21
0.52
e6/l
2.23
90
718
8
33
2.45
1.54
3.0
2.2
—
—
—
0
0
5
15
3.36
1.52
1.8
1.3
—
—
—
0
0
9
37
2.46
1.48
1.2
1.2
—
—
—
0
0
7
28
2.52
1.45
1.0
1.3
—
—
—
0
0
269
2460
1.24
1.41
4.1
3.1
44.60
47.39
u/l
0.29
253
2297
358
3391
1.31
1.35
4.9
4.8
1.87
2.26
mu/l
0.55
330
3092
22
136
1.65
1.35
1.7
2.1
—
—
—
0
0
147
1264
1.25
1.35
4.0
3.4
2.36
2.36
mmol/l
0.07
123
1117
12
61
1.99
1.34
1.8
1.5
—
—
—
0
0
367
3492
1.31
1.31
15.7
12.6
82.17
80.96
ml/min/173m2
0.56
327
2880
139
1193
1.24
1.29
3.5
3.2
32.78
31.77
u/l
0.13
133
1142
21
130
1.65
1.29
1.7
1.8
—
—
—
0
0
10
48
2.11
1.28
1.3
1.1
—
—
—
0
0
145
1253
1.24
1.26
3.8
3.1
—
—
—
0
0
16
93
1.75
1.23
1.6
1.7
—
—
—
0
0
59
457
1.34
1.22
5.2
4.4
34.39
32.20
%
0.79
49
299
391
3763
1.36
1.21
19.8
15.5
139.69
139.73
mmol/l
0.12
386
3666
380
3646
1.32
1.17
17.1
13.6
22.50
22.24
mg/l
0.05
323
2877
11
58
1.92
1.13
1.7
1.5
—
—
—
0
0
7
30
2.35
1.13
1.1
1.8
—
—
—
0
0
50
383
1.34
1.12
15.5
6.9
1.11
1.35
mmol/l
0.20
40
309
10
51
1.98
1.12
1.3
1.5
—
—
—
0
0
10
51
1.98
1.12
1.3
1.5
—
—
—
0
0
10
51
1.98
1.12
1.3
1.5
—
—
—
0
0
5
21
2.40
1.09
4.4
2.0
—
—
—
0
0
16
97
1.67
1.08
1.6
1.7
—
—
—
0
0
10
52
1.94
1.07
1.3
1.5
—
—
—
0
0
10
52
1.94
1.07
1.3
1.5
—
—
—
0
0
10
52
1.94
1.07
1.3
1.5
—
—
—
0
0
16
98
1.66
1.04
1.1
1.3
—
—
—
0
0
5
22
2.29
1.03
8.8
1.6
111.20
108.45
%
—
5
22
53
417
1.31
1.01
16.5
6.1
105.32
104.08
mmol/l
1.57
53
417
11
61
1.82
0.99
4.1
4.0
35.00
37.27
umol/l
0.17
11
48
93
787
1.23
0.98
3.7
4.1
1.02
1.02
kg/l
0.03
13
102
70
574
1.26
0.97
1.9
1.9
—
—
—
0
0
155
1380
1.19
0.97
4.0
3.9
—
—
—
0
0
390
3775
1.30
0.95
19.9
15.6
3.96
3.97
mmol/l
0.24
385
3673
12
70
1.73
0.93
2.1
1.8
5249.60
734.46
u/l
—
5
21
128
1124
1.20
0.93
2.3
2.1
178.58
182.88
u/l
0.04
123
1063
29
212
1.39
0.89
1.2
1.4
—
—
—
0
0
15
95
1.60
0.88
1.2
1.3
—
—
—
0
0
8
44
1.83
0.86
1.9
1.6
—
—
—
0
0
12
72
1.69
0.86
3.8
3.8
58.17
56.99
%
0.08
12
72
401
3905
1.32
0.85
12.2
10.4
27.04
25.63
u/l
0.78
389
3771
96
829
1.20
0.83
1.7
1.5
21.18
22.19
nmol/l
0.25
79
701
71
595
1.23
0.83
1.6
1.5
—
—
—
0
0
8
46
1.75
0.83
1.3
2.0
—
—
—
0
0
79
673
1.21
0.79
1.7
1.7
1220.81
1192.78
nmol/l
0.11
57
494
54
443
1.25
0.77
6.5
7.0
—
—
—
0
0
12
75
1.62
0.75
1.1
1.1
74.43
3.09
e6/l
—
7
56
20
142
1.43
0.73
1.5
1.7
—
—
—
0
0
161
1468
1.15
0.72
2.1
1.9
107.00
96.52
pmol/l
1.37
84
725
107
947
1.17
0.71
2.6
2.6
329.66
6547.37
umol/l
3.95
98
834
7
41
1.72
0.70
1.0
1.0
—
—
—
0
0
7
41
1.72
0.70
1.3
2.1
—
—
—
0
0
101
1137
0.85
0.69
3.4
3.1
7.22
7.42
mmol/l
0.17
85
951
11
69
1.61
0.69
2.6
4.1
28.83
25.88
mg/l
—
6
42
32
250
1.30
0.68
1.1
1.2
98.81
148.69
iu/ml
0.39
11
101
10
62
1.63
0.65
2.1
1.4
—
—
—
0
0
49
407
1.23
0.64
1.7
1.8
—
—
—
0
0
11
71
1.56
0.62
3.4
3.3
4.93
4.38
e9/l
0.25
11
71
37
299
1.26
0.62
5.8
3.4
1.97
2.31
mmol/l
0.29
32
246
27
209
1.31
0.62
4.6
3.6
2.12
1.99
mmol/l
0.05
22
153
78
681
1.18
0.62
3.2
2.9
2.43
2.45
mmol/l
0.97
69
593
22
166
1.34
0.60
1.0
1.0
—
—
—
0
0
49
412
1.21
0.58
1.8
1.8
—
—
—
0
0
78
688
1.16
0.55
1.2
1.3
14.17
36.75
iu/ml
4.49
23
238
16
116
1.39
0.55
1.1
1.3
—
—
—
0
0
16
116
1.39
0.55
1.5
1.6
—
—
—
0
0
6
39
1.55
0.53
1.2
1.8
—
—
—
0
0
6
39
1.55
0.53
1.2
1.8
—
—
—
0
0
6
39
1.55
0.53
1.2
1.8
—
—
—
0
0
412
4057
1.26
0.51
25.6
20.0
39.44
40.20
%
1.62
387
3803
412
4057
1.26
0.51
24.7
20.1
254.24
253.61
e9/l
0.07
402
3958
114
1040
1.13
0.50
2.6
3.0
1211.92
1118.86
ng/l
0.09
99
871
15
110
1.38
0.49
3.0
2.4
—
—
—
0
0
96
868
1.14
0.49
2.2
2.0
3.27
3.22
mg/l
0.07
83
732
7
45
1.56
0.49
1.0
1.2
0.49
0.58
nmol/l
—
7
40
102
1119
0.88
0.48
4.1
3.8
4.27
8.05
mg/mmol
1.27
63
679
13
93
1.41
0.48
1.4
1.4
—
—
—
0
0
412
4060
1.25
0.47
24.6
20.1
4.42
4.48
e12/l
1.58
403
3952
15
111
1.36
0.47
1.6
1.6
—
—
—
0
0
167
1565
1.11
0.46
2.9
2.6
143.42
118.98
ug/l
0.33
151
1425
13
94
1.39
0.46
1.4
1.1
—
—
—
0
0
16
121
1.33
0.45
2.9
1.9
—
—
—
0
0
7
51
1.38
0.44
1.4
1.1
—
—
—
0
0
75
673
1.14
0.43
4.4
4.1
20.44
21.51
%
0.26
39
303
5
31
1.62
0.43
1.4
1.2
—
—
—
0
0
5
31
1.62
0.43
1.4
1.2
—
—
—
0
0
36
305
1.20
0.42
6.0
3.4
5.71
5.84
kpa
0.43
36
297
84
762
1.13
0.41
1.4
1.7
186567628.18
442.78
pmol/l
0.79
67
634
24
195
1.24
0.41
1.7
1.3
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
9
67
1.35
0.38
1.4
1.4
—
—
—
0
0
6
41
1.47
0.36
1.5
1.0
—
—
—
0
0
65
588
1.12
0.34
1.4
1.4
—
—
—
0
0
30
256
1.18
0.34
5.6
2.7
4.34
4.43
kpa
0.12
30
247
35
303
1.17
0.34
2.2
2.4
10.83
7.03
ug/l
0.51
28
269
15
118
1.28
0.34
1.5
1.8
—
—
—
0
0
56
504
1.13
0.33
2.9
2.2
2.32
2.33
g/l
0.01
50
462
12
93
1.30
0.30
1.8
1.5
—
—
—
0
0
8
62
1.30
0.28
1.4
1.7
235.38
230.64
pmol/l
—
8
56
8
66
1.22
0.27
1.5
1.2
—
—
—
0
0
347
3411
1.08
0.25
5.4
5.8
39.16
39.75
mmol/mol
0.67
317
3181
87
817
1.08
0.24
2.1
1.6
2.30
1.09
mg/l
0.47
65
633
362
3569
1.08
0.23
4.5
4.6
5.90
5.93
mmol/l
0.16
334
3257
5
40
1.25
0.22
2.0
2.3
—
—
—
0
0
10
79
1.27
0.22
1.4
1.4
—
—
—
0
0
5
42
1.19
0.21
1.2
1.4
0.18
0.24
nmol/l
—
5
29
0
11
0.00
0.21
0.0
1.7
—
7.64
—
0
11
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
6
51
1.18
0.19
2.2
2.5
106.50
105.31
mmol/l
—
6
51
11
90
1.23
0.19
1.5
1.4
—
—
—
0
0
357
3613
0.94
0.18
4.5
4.4
1.52
1.51
mmol/l
0.16
340
3341
47
436
1.09
0.18
9.3
5.3
0.99
1.04
mmol/l
0.69
42
402
8
69
1.16
0.16
1.3
1.9
—
—
—
0
0
8
69
1.16
0.16
1.3
1.9
—
—
—
0
0
18
158
1.15
0.16
2.4
2.3
0.68
0.65
%
0.14
18
158
39
363
1.08
0.14
3.0
3.3
—
—
—
0
0
360
3634
0.95
0.14
4.5
4.5
4.76
4.77
mmol/l
0.06
340
3384
34
316
1.08
0.13
1.6
1.9
—
—
—
0
0
35
326
1.08
0.13
1.9
1.7
—
—
—
0
0
10
85
1.18
0.12
1.2
1.8
—
—
—
0
0
32
298
1.08
0.12
2.4
2.7
64.08
66.24
ml/min/173m2
0.11
12
127
11
95
1.16
0.11
1.5
1.2
175.60
256.24
miu/ml
—
5
42
5
44
1.14
0.10
1.2
1.4
—
—
—
0
0
5
45
1.11
0.10
1.4
1.4
—
—
—
0
0
5
45
1.11
0.10
1.4
1.4
—
—
—
0
0
5
45
1.11
0.10
1.4
1.4
—
—
—
0
0
5
47
1.06
0.09
1.4
1.8
—
—
—
0
0
5
47
1.06
0.09
1.4
1.8
—
—
—
0
0
6
54
1.11
0.09
2.7
1.7
—
—
—
0
0
230
2272
1.03
0.08
2.9
2.9
—
—
—
0
0
53
511
1.04
0.07
3.6
2.9
0.77
0.71
ug/l
0.30
36
315
369
3710
0.97
0.07
4.9
5.0
2.82
2.81
mmol/l
0.07
350
3425
49
473
1.04
0.06
3.2
2.3
21.43
22.98
%
0.29
41
409
10
90
1.11
0.05
1.2
1.2
—
—
—
0
0
100
1018
0.98
0.05
1.8
1.7
1.34
1.38
mmol/l
0.28
92
864
351
3496
1.02
0.03
4.0
4.0
1.29
1.30
mmol/l
0.15
331
3209
29
281
1.03
0.02
1.4
1.8
—
—
—
0
0
85
843
1.01
0.01
5.2
4.6
3.01
2.50
ug/l
0.37
78
761
12
115
1.04
0.00
1.5
1.6
90.39
295.50
ug/g
—
7
69
10
97
1.03
0.00
1.5
1.3
—
—
—
0
0
12
121
0.99
0.00
1.3
1.1
—
—
—
0
0
12
121
0.99
0.00
1.3
1.1
—
—
—
0
0
13
129
1.01
0.00
1.5
1.4
—
—
—
0
0
65
653
0.99
0.00
1.3
1.2
4.01
10.19
u/ml
1.13
19
252
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
22.55
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
8
88
0.91
-0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
119.17
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
65.67
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
90.71
—
0
7
6
66
0.91
-0.00
1.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.6
1.5
—
—
—
0
0
6
66
0.91
-0.00
1.0
1.3
—
—
—
0
0
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
85
0.94
-0.00
2.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
6.66
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
168.50
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
60.30
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint K11_OTHAPPEND and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_OTHAPPEND | 1.183 [0.87, 1.6] | 0.277 |
| Birth year | 0.996 [0.99, 1.0] | 0.385 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 525 females with K11_OTHAPPEND died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_OTHAPPEND | 1.303 [0.91, 1.86] | 0.142 |
| Birth year | 0.989 [0.98, 1.0] | 0.026 |
During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 371 males with K11_OTHAPPEND died.
Mortality risk
Mortality risk for people of age
years, who have K11_OTHAPPEND.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.09% | 0.251% |
| 5 | 0.711% | 1.634% |
| 10 | 1.591% | 4.017% |
| 15 | 3.205% | 7.607% |
| 20 | 6.275% | 13.089% |
Relationships between endpoints
↥Index endpoint: K11_OTHAPPEND – Other diseases of appendix
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data