No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
314 |
4. Check minimum number of eventsNone |
314 |
5. Include endpointsNone |
314 |
6. Filter based on genotype QC (FinnGen only) |
314 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D22
- Name in latin
- Naevus melanocyticus (cutis) labii (oris)
Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 2143 | 1358 | 781 |
Only index persons | 2030 | 1302 | 728 |
Unadjusted period prevalence (%) | |||
Whole population | 0.03 | 0.04 | 0.02 |
Only index persons | 0.04 | 0.05 | 0.03 |
Median age at first event (years) | |||
Whole population | 39.45 | 40.56 | 37.57 |
Only index persons | 38.35 | 40.23 | 35.00 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 314 | 237 | 77 |
Unadjusted period prevalence (%) | 0.07 | 0.08 | 0.03 |
Median age at first event (years) | 43.83 | 42.12 | 49.11 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 291
- Matched controls
- 2911
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MELANOCYTIC_LIP and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_MELANOCYTIC_LIP | 0.855 [0.68, 1.07] | 0.173 |
Birth year | 1.0 [0.99, 1.01] | 0.977 |
During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 1211 females with CD2_BENIGN_MELANOCYTIC_LIP died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_MELANOCYTIC_LIP | 1.024 [0.79, 1.32] | 0.855 |
Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 99 out of 689 males with CD2_BENIGN_MELANOCYTIC_LIP died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MELANOCYTIC_LIP.N-year risk | Females | Males |
---|---|---|
1 | 0.102% | 0.184% |
5 | 0.639% | 1.242% |
10 | 1.545% | 3.197% |
15 | 2.804% | 5.88% |
20 | 4.939% | 10.045% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MELANOCYTIC_LIP – Melanocytic naevi of lip
GWS hits: -