Melanocytic naevi of lip

CD2_BENIGN_MELANOCYTIC_LIP

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D22.0&
  • Hospital discharge: ICD-9 2160A
  • Cause of death: ICD-10 D22.0&
  • Cause of death: ICD-9 2160A

2 out of 7 registries used, show all original rules.

319

4. Check minimum number of events

None

319

5. Include endpoints

None

319

6. Filter based on genotype QC (FinnGen only)

311

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) labii (oris)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2143 1358 781
Only index persons 2030 1302 728
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.02
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 39.45 40.56 37.57
Only index persons 38.35 40.23 35.00

-FinnGen-

Key figures

All Female Male
Number of individuals 311 234 77
Unadjusted period prevalence (%) 0.07 0.08 0.04
Median age at first event (years) 44.11 42.47 49.11

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
319
Matched controls
3190
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D22.0
ICD-10 Finland
Melanocytic naevi of lip
4503599627370496.0
307.7
291
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
8.4
54.4
83
128
2160A
ICD-9 Finland
Benign neoplasm of skin, Skin of lip[HUULEN IHON BENIGNI KASVAIN,NAEVUS PIGMENTOSUS]
+∞
29.6
28
*
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
6.5
28.9
52
93
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
5.8
24.2
48
94
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
5.9
23.2
45
86
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.3
18.4
52
137
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
5.8
12.3
23
42
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
9.3
12.3
25
29
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
9.5
12.0
24
27
EAA10
NOMESCO Finland
Excision of lesion of lip
17.4
10.0
15
9
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.6
9.5
32
95
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
7.5
8.9
20
28
9733
FHL
Excision of skin change in operating room or anesthesia
7.7
7.8
17
23
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
3.8
7.2
22
61
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
7.3
6.3
14
20
S82
ICPC
Naevus/mole
2.2
6.1
53
261

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
145
1070
1.65
4.58
2.5
2.0
—
—
—
0
0
55
309
1.94
4.43
3.1
2.2
23.80
22.51
%
0.27
48
269
100
691
1.65
3.98
3.1
3.0
6.69
7.35
mmol/l
0.67
82
590
89
619
1.61
3.38
3.3
3.1
2307.94
154.57
mg/l
1.00
54
396
93
660
1.58
3.23
3.9
3.7
9.15
7.40
mg/mmol
0.14
58
402
121
932
1.48
2.82
2.0
1.9
99.18
95.35
pmol/l
0.33
55
465
130
1027
1.45
2.62
3.7
4.1
36.73
36.10
g/l
0.70
124
965
150
1221
1.43
2.56
6.9
5.9
—
—
—
0
0
5
7
7.23
2.56
1.2
1.1
—
—
—
0
0
162
1339
1.43
2.53
6.3
5.7
0.21
0.18
e9/l
1.08
141
1184
55
366
1.61
2.47
2.7
2.8
2.10
3.03
e6/l
0.47
24
190
226
1991
1.46
2.45
4.2
3.9
12.06
10.95
mm/h
0.51
212
1845
156
1293
1.40
2.34
6.3
5.4
0.53
0.55
e9/l
0.74
133
1128
42
265
1.67
2.32
2.3
1.5
—
—
—
0
0
79
1040
0.68
2.29
3.0
2.7
—
—
—
0
0
5
9
5.62
2.22
1.0
1.1
—
—
—
0
0
207
1811
1.41
2.21
4.7
4.0
—
—
—
0
0
29
168
1.80
2.16
1.1
1.2
—
—
—
0
0
7
19
3.74
2.16
1.0
1.0
—
—
—
0
0
155
1296
1.38
2.15
6.3
5.4
0.04
0.04
e9/l
0.46
132
1131
8
26
3.13
2.02
1.4
1.3
—
—
—
0
0
157
1329
1.36
1.96
6.4
5.4
1.97
2.01
e9/l
0.09
141
1191
20
106
1.95
1.95
1.5
1.5
196.91
246.99
miu/ml
0.32
11
59
43
286
1.58
1.95
1.7
2.6
7.14
7.76
umol/l
0.14
37
241
79
602
1.42
1.86
2.3
2.0
2.74
3.06
mg/l
0.63
68
514
282
2649
1.56
1.76
16.3
13.8
139.41
139.71
mmol/l
1.05
275
2570
232
2107
1.37
1.73
4.6
4.1
14.52
14.60
pmol/l
0.20
213
1937
46
325
1.49
1.61
1.5
1.2
—
—
—
0
0
267
2492
1.44
1.61
5.7
4.8
1.89
2.29
mu/l
0.39
252
2298
138
1172
1.31
1.59
6.7
5.4
0.70
0.68
%
0.26
127
1085
174
1529
1.30
1.55
9.7
8.8
4.16
4.03
e9/l
0.35
150
1341
5
15
3.37
1.53
2.0
6.2
—
—
—
0
0
281
2656
1.49
1.50
17.0
13.8
3.95
3.95
mmol/l
0.06
275
2575
44
314
1.47
1.47
2.1
1.8
—
—
—
0
0
155
1348
1.29
1.47
5.4
5.6
12.14
10.46
umol/l
0.81
149
1281
51
375
1.43
1.46
1.6
1.4
236.92
509.57
titre
2.05
13
92
12
59
2.07
1.45
1.2
1.3
—
—
—
0
0
72
566
1.35
1.40
3.3
3.5
—
—
—
0
0
15
82
1.87
1.38
1.3
1.3
—
—
—
0
0
55
415
1.39
1.37
1.6
1.7
1357.96
1242.27
nmol/l
0.24
46
301
32
220
1.51
1.29
1.1
1.1
—
—
—
0
0
64
501
1.35
1.28
1.3
1.3
1.33
10.45
u/ml
3.41
30
194
217
1992
1.28
1.25
7.6
6.9
75.99
76.79
u/l
0.09
203
1875
143
1250
1.26
1.24
6.6
5.9
1.22
1.22
mmol/l
0.43
125
1045
19
116
1.68
1.24
5.7
11.9
—
—
—
0
0
19
116
1.68
1.24
3.4
2.2
—
—
—
0
0
94
781
1.29
1.23
3.4
2.7
—
—
—
0
0
126
1088
1.26
1.21
2.3
2.3
80.25
76.57
nmol/l
1.03
115
983
142
1244
1.25
1.20
3.4
2.7
102.71
90.47
ug/l
0.43
137
1155
140
1225
1.25
1.20
6.6
5.4
3.18
2.76
%
1.02
129
1144
8
39
2.08
1.16
2.4
1.9
13.75
13.23
%
—
8
39
140
1231
1.24
1.13
6.8
5.6
8.12
8.27
%
0.27
130
1153
23
152
1.55
1.12
2.8
2.7
66.08
69.28
e9/l
0.23
15
116
43
324
1.38
1.10
2.4
2.1
—
—
—
0
0
5
21
2.40
1.09
1.4
1.1
—
—
—
0
0
45
343
1.36
1.08
1.2
1.2
—
—
—
0
0
252
2375
1.29
1.07
20.0
14.9
14.90
14.69
%
0.23
247
2344
22
146
1.54
1.06
1.2
1.3
27.01
27.56
iu/l
0.02
22
124
292
2813
1.45
1.05
11.4
9.5
25.71
25.00
u/l
0.36
284
2725
13
77
1.72
0.96
3.9
3.0
—
—
—
0
0
290
2798
1.40
0.95
15.9
11.5
—
—
—
0
0
10
170
0.57
0.93
2.0
1.7
—
—
—
0
0
139
1242
1.21
0.92
6.4
5.3
58.30
56.63
%
1.00
129
1164
141
1262
1.21
0.92
6.7
5.5
28.24
28.77
%
0.24
131
1187
304
2961
1.57
0.91
23.8
18.4
259.57
255.65
e9/l
0.53
299
2895
56
453
1.29
0.91
3.3
3.1
410.63
150.66
ng/l
0.65
40
316
94
809
1.23
0.90
2.0
2.3
53.16
62.61
u/l
0.84
88
753
6
29
2.09
0.89
1.0
1.2
—
—
nmol/l
—
0
0
35
265
1.36
0.89
3.3
3.9
2.21
49.97
ug/l
0.93
29
216
304
2963
1.55
0.88
23.7
18.3
30.07
30.17
pg
0.46
299
2922
304
2963
1.55
0.88
23.7
18.3
90.37
90.67
fl
0.58
299
2922
25
179
1.43
0.87
1.7
1.3
—
—
—
0
0
304
2964
1.55
0.86
23.8
18.4
6.78
6.66
e9/l
0.44
298
2891
304
2964
1.55
0.86
23.8
18.4
4.47
4.48
e12/l
0.12
298
2893
6
31
1.95
0.85
2.3
1.7
—
—
—
0
0
249
2365
1.24
0.84
5.9
5.2
39.31
39.17
mmol/mol
0.09
228
2218
304
2966
1.53
0.83
23.9
18.5
133.68
134.41
g/l
0.48
299
2925
29
216
1.38
0.82
1.5
1.4
—
—
—
0
0
278
2678
1.30
0.80
14.7
12.3
18.07
21.05
mg/l
1.23
212
2079
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
103
906
1.20
0.79
4.0
3.6
110.62
73.79
e6/l
0.28
66
625
41
327
1.29
0.75
1.7
1.6
—
—
—
0
0
15
100
1.52
0.74
1.3
1.6
—
10.08
—
0
5
60
503
1.24
0.74
1.2
1.3
38.07
27.24
iu/ml
0.21
18
161
5
25
2.02
0.73
1.2
1.1
—
—
—
0
0
5
25
2.02
0.73
1.2
1.0
—
—
titre
—
0
0
303
2962
1.46
0.72
23.1
18.4
39.59
40.05
%
0.61
276
2804
262
2515
1.23
0.72
4.8
4.2
5.72
5.82
mmol/l
0.96
244
2312
79
684
1.21
0.71
3.3
2.9
0.75
0.44
e6/l
0.73
53
517
33
258
1.31
0.70
4.7
8.3
1.77
1.32
mmol/l
0.32
24
211
36
285
1.30
0.70
5.5
5.9
101.33
104.33
mmol/l
1.68
36
285
13
85
1.55
0.70
1.3
1.9
—
—
—
0
0
66
564
1.21
0.68
1.5
1.5
21.85
21.57
nmol/l
0.06
58
467
14
202
0.68
0.68
1.8
1.4
—
—
—
0
0
7
43
1.64
0.67
1.6
3.5
—
—
—
0
0
7
43
1.64
0.67
1.3
1.1
—
—
—
0
0
135
1232
1.17
0.66
2.7
2.4
—
—
—
0
0
125
1134
1.17
0.66
5.7
5.4
1.22
1.22
mmol/l
0.02
114
1037
83
728
1.19
0.65
2.2
2.0
222.62
240.33
u/l
0.05
78
692
19
138
1.40
0.64
3.8
7.4
—
—
—
0
0
5
29
1.74
0.64
1.0
1.1
—
—
—
0
0
85
750
1.18
0.63
3.4
3.1
47.20
131.38
e6/l
0.46
60
578
57
485
1.21
0.62
1.8
1.7
494.96
30073797.84
pmol/l
0.78
49
409
79
695
1.18
0.60
3.7
3.5
—
—
—
0
0
13
185
0.69
0.60
3.8
3.2
—
—
—
0
0
32
256
1.28
0.59
4.8
8.4
5.36
5.23
kpa
0.28
27
248
32
256
1.28
0.59
4.8
8.4
12.38
12.73
kpa
0.11
27
248
0
22
0.00
0.59
0.0
1.6
—
—
—
0
0
27
211
1.31
0.59
1.3
2.4
0.23
0.22
g/l
0.20
27
196
15
106
1.44
0.59
1.5
1.2
—
—
—
0
0
191
1800
1.15
0.58
3.0
2.9
46.43
40.46
u/l
0.51
182
1698
189
1784
1.15
0.55
3.8
3.5
—
—
—
0
0
76
672
1.17
0.55
1.3
1.2
0.60
2.03
u/ml
1.27
20
181
31
250
1.27
0.55
2.3
2.2
32.00
28.66
u/l
0.51
24
212
11
74
1.50
0.54
1.2
2.2
38.44
38.19
g/l
0.05
11
69
130
1202
1.14
0.51
11.5
8.6
0.00
0.00
e9/l
0.39
100
998
140
1302
1.13
0.50
3.8
3.5
0.00
0.00
estimate
-0.00
28
289
12
166
0.71
0.49
2.1
2.4
—
—
—
0
0
52
451
1.18
0.48
2.4
2.8
2.42
2.45
mmol/l
0.90
40
401
67
595
1.16
0.46
1.4
1.3
2.09
2.23
g/l
0.33
39
358
7
49
1.44
0.46
1.3
1.9
—
—
—
0
0
11
77
1.44
0.46
1.5
3.4
0.26
0.23
g/l
—
6
24
29
350
0.81
0.46
1.8
2.3
59.10
122.53
ug/g
1.89
20
272
82
904
0.87
0.45
2.9
3.4
25.83
69.20
ng/l
0.52
48
580
57
501
1.17
0.45
4.2
2.6
549.47
535.12
mosm/kgh2o
0.16
45
431
18
139
1.31
0.44
1.6
2.3
9155.70
2204.33
u/l
—
5
53
14
104
1.36
0.44
3.9
2.0
0.70
0.67
%
0.11
14
104
94
860
1.13
0.43
3.1
3.1
2.37
2.35
mmol/l
0.47
87
774
5
31
1.62
0.43
1.0
1.2
—
—
—
0
0
5
31
1.62
0.43
3.2
3.0
—
—
—
0
0
117
1086
1.12
0.42
15.8
11.6
1.33
1.21
inr
0.54
29
330
5
32
1.57
0.42
4.0
2.3
102.00
106.03
mmol/l
—
5
32
5
32
1.57
0.42
4.0
2.3
—
—
—
0
0
5
32
1.57
0.42
4.0
2.3
3.96
3.98
mmol/l
—
5
32
13
96
1.37
0.42
1.6
1.3
—
—
—
0
0
13
96
1.37
0.42
1.3
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
550245.00
—
0
10
0
15
0.00
0.41
0.0
1.0
—
260.33
—
0
9
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
5
34
1.48
0.40
1.2
1.4
68.02
58.83
%
—
5
34
5
34
1.48
0.40
1.8
2.6
—
—
—
0
0
13
97
1.35
0.40
1.7
1.3
—
—
—
0
0
7
104
0.67
0.40
1.4
1.6
—
—
—
0
0
114
1061
1.12
0.39
3.6
3.3
5.86
5.84
ph
—
7
79
139
1308
1.11
0.39
5.5
4.8
0.00
0.00
estimate
-0.00
27
268
5
36
1.39
0.38
1.2
1.0
—
—
—
0
0
64
707
0.88
0.37
4.2
3.8
0.00
0.00
estimate
-0.00
24
270
13
99
1.33
0.36
1.7
1.4
—
—
—
0
0
6
42
1.44
0.35
1.2
1.0
—
—
—
0
0
88
812
1.12
0.35
2.2
2.1
—
—
—
0
0
75
686
1.12
0.35
3.2
2.8
—
—
—
0
0
27
317
0.84
0.34
1.5
1.3
—
—
—
0
0
26
220
1.20
0.33
3.1
2.9
0.74
0.77
ug/l
0.10
17
135
270
2644
1.14
0.33
5.2
4.5
2.73
2.82
mmol/l
0.95
250
2455
61
555
1.12
0.31
4.0
3.7
1.01
1.02
kg/l
—
6
69
72
781
0.90
0.31
1.6
1.5
—
—
—
0
0
31
356
0.86
0.31
1.7
1.7
—
—
—
0
0
139
1321
1.09
0.31
3.8
3.6
0.00
0.01
estimate
0.50
25
259
15
120
1.26
0.30
1.3
1.5
—
—
—
0
0
15
120
1.26
0.30
1.3
1.5
—
—
—
0
0
15
120
1.26
0.30
1.3
1.5
—
—
—
0
0
14
112
1.26
0.29
1.4
1.5
—
—
—
0
0
18
149
1.22
0.28
1.3
2.3
—
—
—
0
0
28
321
0.86
0.28
1.4
1.4
—
—
—
0
0
73
676
1.10
0.28
8.0
7.0
—
—
—
0
0
254
2488
1.10
0.26
4.1
3.7
1.34
1.25
mmol/l
0.40
232
2295
9
73
1.24
0.25
2.4
2.6
—
—
—
0
0
9
77
1.17
0.24
9.7
9.7
—
—
—
0
0
10
78
1.29
0.24
1.1
1.2
—
—
—
0
0
6
81
0.74
0.24
1.0
1.1
9.38
12.48
u/l
—
6
64
6
82
0.73
0.24
1.3
1.2
—
—
—
0
0
65
604
1.10
0.24
2.8
2.4
319.54
5705.41
umol/l
2.53
54
530
15
125
1.21
0.23
6.0
3.1
—
—
—
0
0
152
1465
1.07
0.22
3.8
4.4
6.77
6.54
mmol/l
0.62
132
1339
25
283
0.87
0.22
1.4
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
5
43
1.17
0.21
1.2
2.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
184.74
—
0
14
21
237
0.88
0.18
2.8
3.6
—
—
—
0
0
10
121
0.82
0.18
1.1
1.1
—
—
—
0
0
263
2594
1.08
0.17
4.6
4.1
1.53
1.53
mmol/l
0.00
244
2405
13
152
0.85
0.17
1.1
1.1
—
106.20
—
0
5
8
68
1.18
0.16
9.8
3.8
—
—
—
0
0
14
120
1.17
0.16
1.4
1.5
—
—
—
0
0
11
92
1.20
0.16
5.8
3.9
—
—
—
0
0
9
78
1.16
0.15
1.2
1.3
—
3.23
—
0
11
21
188
1.13
0.15
2.9
2.9
22.43
37.27
u/ml
0.97
21
180
21
188
1.13
0.15
9.2
3.7
0.56
0.76
%
—
9
56
52
490
1.07
0.14
2.0
1.7
—
—
—
0
0
73
701
1.05
0.12
1.7
1.6
1.26
1.36
mmol/l
0.62
61
597
57
596
0.95
0.11
2.2
2.0
—
—
—
0
0
81
782
1.05
0.11
4.9
3.5
7.40
7.40
ph
0.14
12
147
263
2606
1.05
0.10
4.7
4.1
4.71
4.76
mmol/l
0.32
248
2431
5
45
1.11
0.10
8.6
2.6
—
—
—
0
0
5
45
1.11
0.10
1.4
1.3
—
—
—
0
0
5
47
1.06
0.09
1.8
2.4
8.10
8.23
kpa
—
5
47
20
184
1.09
0.09
6.6
6.5
—
—
—
0
0
5
62
0.80
0.08
1.8
2.2
—
—
—
0
0
5
63
0.79
0.08
1.2
1.1
—
—
—
0
0
11
98
1.13
0.07
1.1
1.1
—
—
—
0
0
6
71
0.84
0.07
1.0
1.2
—
—
—
0
0
21
196
1.08
0.07
9.8
4.0
0.00
0.16
%
—
10
58
61
592
1.04
0.06
7.3
4.1
—
—
—
0
0
57
587
0.96
0.06
1.8
1.7
1.11
0.97
mg/l
0.25
38
446
30
314
0.95
0.06
1.6
1.4
—
—
—
0
0
16
150
1.07
0.04
1.0
1.1
—
—
—
0
0
26
249
1.05
0.04
1.7
1.4
—
—
—
0
0
54
528
1.03
0.03
2.9
2.5
6.21
7.28
e6/l
0.23
44
478
78
768
1.02
0.03
3.4
3.1
—
—
—
0
0
22
211
1.05
0.03
3.6
4.0
—
—
—
0
0
12
112
1.07
0.03
1.7
1.8
—
—
—
0
0
17
164
1.04
0.00
1.2
1.2
—
—
—
0
0
14
138
1.02
0.00
4.8
5.0
24.78
25.13
mmol/l
0.14
14
138
23
227
1.01
0.00
1.1
1.2
50.04
180.12
iu/ml
—
9
95
21
206
1.02
0.00
1.8
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
3.70
—
0
6
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
5
49
1.02
-0.00
3.6
2.2
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
1.19
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
19
190
1.00
-0.00
10.1
3.9
0.00
0.33
%
—
7
52
21
210
1.00
-0.00
9.8
3.8
0.60
0.83
%
—
10
72
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
8
85
0.94
-0.00
1.4
2.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.67
—
0
5
0
7
0.00
-0.00
0.0
2.3
—
1.42
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.91
—
0
5
5
52
0.96
-0.00
1.2
1.3
—
—
—
0
0
9
90
1.00
-0.00
1.7
1.9
20.11
21.23
s
—
9
75
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
10.66
—
0
6
0
8
0.00
-0.00
0.0
14.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
15.10
—
0
5
5
53
0.94
-0.00
2.8
2.8
25.52
24.55
mmol/l
—
5
53

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MELANOCYTIC_LIP and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_LIP 0.855 [0.68, 1.07] 0.173
Birth year 1.0 [0.99, 1.01] 0.977

During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 1211 females with CD2_BENIGN_MELANOCYTIC_LIP died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_LIP 1.024 [0.79, 1.32] 0.855
Birth year 0.988 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 99 out of 689 males with CD2_BENIGN_MELANOCYTIC_LIP died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MELANOCYTIC_LIP.

N-year risk Females Males
1 0.102% 0.184%
5 0.639% 1.242%
10 1.545% 3.197%
15 2.804% 5.88%
20 4.939% 10.045%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MELANOCYTIC_LIP – Melanocytic naevi of lip

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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