No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
428 |
4. Check minimum number of eventsNone |
428 |
5. Include endpointsNone |
428 |
6. Filter based on genotype QC (FinnGen only) |
408 |
Control definitions (FinnGen only)
- Control exclude
- M13_ARTHROPATHIES
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M21
- Name in latin
- Deformitas membri vara non alibi classificata
Similar endpoints
↥List of similar endpoints to
Varus deformity, not elsewhere classified
based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3785 | 2650 | 1120 |
| Only index persons | 3415 | 2455 | 960 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.08 | 0.03 |
| Only index persons | 0.08 | 0.09 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 51.91 | 55.37 | 43.69 |
| Only index persons | 51.77 | 54.93 | 43.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 408 | 324 | 84 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.04 |
| Median age at first event (years) | 51.46 | 52.11 | 48.95 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 428
- Matched controls
- 4280
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M21.1
ICD-10 Finland
Varus deformity, not elsewhere classified
+∞
307.7
368
*
M20.1
ICD-10 Finland
Hallux valgus (acquired)
166.9
307.7
235
31
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
+∞
142.9
129
*
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
73.1
142.6
78
13
M17.1
ICD-10 Finland
Other primary gonarthrosis
19.5
135.9
117
81
M19.0
ICD-10 Finland
Primary arthrosis of other joints
30.5
125.2
86
35
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
22.4
91.2
70
37
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
16.2
87.6
80
60
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
140.0
85.7
89
8
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
78.6
73
*
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
15.3
75.1
70
54
ZXA00
NOMESCO Finland
Right side
5.2
60.0
182
534
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
+∞
57.6
54
*
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
15.5
56.3
51
37
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
12.5
53.9
56
51
ZXA05
NOMESCO Finland
Left side
4.8
51.6
166
502
M16.1
ICD-10 Finland
Other primary coxarthrosis
15.7
49.2
44
31
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
46.7
44
*
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
+∞
45.6
43
*
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
64.1
44.5
51
9
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
43.5
41
*
WX320
NOMESCO Finland
Spinalanesthesy
4.6
40.9
124
351
NHL20
NOMESCO Finland
Myotomy or tenotomy of foot
+∞
38.1
36
*
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
+∞
37.0
35
*
M25.5
ICD-10 Finland
Pain in joint
3.8
36.9
157
563
M77.4
ICD-10 Finland
Metatarsalgia
6.9
36.9
62
103
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
13.0
36.3
36
30
73803
ICD-8 Finland
Other deformities, Genu varum
+∞
35.9
34
*
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
364.7
34.4
34
*
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
5.8
29.7
59
115
Z25.1
ICD-10 Finland
Need for immunization against influenza
5.8
29.0
57
110
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
4.0
28.2
95
285
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
4.0
27.9
93
277
Z20.9
ICD-10 Finland
Contact with and exposure to unspecified communicable disease
8.3
27.2
37
48
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
80.6
27.1
30
*
N02AX02
ATC
tramadol; systemic, rectal
3.0
26.5
200
978
9271
FHL
Hallux surgery
+∞
26.3
25
*
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
276.4
26.0
26
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
24.7
206
1053
R4110
NOMESCO Finland
Physiotherapy
3.0
23.9
154
684
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
6.2
23.8
43
76
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
9.4
23.6
29
33
M20.2
ICD-10 Finland
Hallux rigidus
57.4
23.3
27
5
NHG82
NOMESCO Finland
Fusion of other tarsal joint
+∞
23.1
22
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
6.1
23.0
42
75
L17
ICPC
Foot/toe symptom/complaint
2.8
21.3
153
714
L04AX03
ATC
methotrexate; systemic
6.9
21.2
34
53
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
63.4
21.1
24
*
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
7.3
21.1
32
47
7350A
ICD-9 Finland
Acquired deformities of toe, Hallux valgus (acquired)
+∞
21.0
20
*
M01AX05
ATC
glucosamine; oral
3.6
20.9
81
264
M01AH05
ATC
etoricoxib; oral
2.7
20.8
276
1733
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
60.6
20.1
23
*
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
209.3
19.7
20
*
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
17.8
19.5
30
18
TQW40
NOMESCO Finland
Remowal of suture of skin
4.9
19.4
45
100
N02AJ06
ATC
codeine and paracetamol; systemic
2.5
19.3
189
1016
Z29.8
ICD-10 Finland
Other specified prophylactic measures
6.2
19.1
34
59
SPAT1229
SPAT
Assessment of need for aid
4.9
18.7
43
95
R5110, ,
SPAT
5.0
18.6
42
91
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
4.0
18.4
56
154
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
28.1
18.0
24
9
N03AX12
ATC
[U] gabapentin; oral
3.3
17.7
78
274
M54.5
ICD-10 Finland
Low back pain
2.5
17.7
169
890
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
99.2
17.7
19
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.6
17.6
44
104
R4110, ,
SPAT
3.7
17.6
61
184
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
4.5
17.2
44
106
P01BA02
ATC
hydroxychloroquine; oral
6.6
17.0
28
45
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.6
16.9
133
638
73799
ICD-8 Finland
Hallux valgus and varus
+∞
16.8
16
*
73801
ICD-8 Finland
Other deformities, Coxa vara
+∞
16.8
16
*
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
16.8
16
*
B01AB05
ATC
enoxaparin; parenteral
2.6
16.5
132
637
N03AX16
ATC
[U] pregabalin
2.7
16.5
109
479
M79.6
ICD-10 Finland
Pain in limb
2.3
15.9
189
1086
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
165.8
15.6
16
*
M22.4
ICD-10 Finland
Chondromalacia patellae
33.0
14.9
19
6
M01AC06
ATC
meloxicam; systemic, rectal
2.3
14.9
163
899
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
4.6
14.6
36
84
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
155.1
14.6
15
*
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
4.9
14.5
33
72
L90
ICPC
Osteoarthrosis of knee
6.5
14.4
24
39
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
13.3
14.1
24
19
NF1AA
NOMESCO Finland
Hip X-ray examination
4.6
14.1
34
78
L15
ICPC
Knee symptom/complaint
2.6
13.7
98
444
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
11.5
13.7
25
23
M01AE03
ATC
ketoprofen; systemic, rectal
2.2
13.6
161
910
NGK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of knee or lower leg
+∞
13.6
13
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.0
13.6
40
107
M23.8
ICD-10 Finland
Other internal derangements of knee
16.9
13.6
21
13
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.4
13.5
35
85
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.2
13.2
57
197
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.5
13.2
47
144
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
23.4
13.0
18
8
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
+∞
12.6
12
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.4
12.5
106
518
M13.9
ICD-10 Finland
Arthritis, unspecified
9.1
12.2
25
29
M19.8
ICD-10 Finland
Other specified arthrosis
6.1
11.9
21
36
WX111
NOMESCO Finland
Local infiltration anesthesia
66.8
11.7
13
*
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
11.0
11.4
21
20
A07EC01
ATC
sulfasalazine; oral, rectal
5.3
11.4
23
45
L88
ICPC
Rheumatoid/seropositive arthritis
18.4
10.8
16
9
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
28.9
10.8
14
5
NH3EA
NOMESCO Finland
Feet X-ray examination with load
61.6
10.7
12
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
61.6
10.7
12
*
M01AH01
ATC
celecoxib; oral
2.5
10.5
72
318
M21.0
ICD-10 Finland
Valgus deformity, not elsewhere classified
+∞
10.5
10
*
Z71.8
ICD-10 Finland
Other specified counselling
2.1
10.4
143
841
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.5
10.4
37
113
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
19.4
10.3
15
8
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.4
10.2
26
62
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.0
10.2
30
80
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
2.9
10.1
51
192
S18
ICPC
Laceration/cut
2.0
10.1
183
1184
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
10.1
103
540
M10.9
ICD-10 Finland
Gout, unspecified
5.3
9.9
20
39
WX002
NOMESCO Finland
Sedation and analgesia
2.4
9.9
79
373
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.9
9.9
48
177
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
11.0
9.9
18
17
L01BA01
ATC
methotrexate; systemic
26.7
9.9
13
5
M48.0
ICD-10 Finland
Spinal stenosis
2.9
9.7
48
179
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
9.6
161
1012
L28
ICPC
Limited function/disability (L)
2.4
9.6
73
338
SPAT1153
SPAT
Removal of sutures
2.0
9.5
123
704
M20.5
ICD-10 Finland
Other deformities of toe(s) (acquired)
102.2
9.5
10
*
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
+∞
9.4
9
*
NHG22
NOMESCO Finland
Fusion of subtalar joint
+∞
9.4
9
*
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
5.1
9.4
20
41
S83.2
ICD-10 Finland
Tear of meniscus, current
4.2
9.2
25
63
M70.6
ICD-10 Finland
Trochanteric bursitis
2.5
9.1
60
259
R52.9
ICD-10 Finland
Pain, unspecified
2.8
9.0
48
186
R51.80
ICD-10 Finland
Headache
2.3
8.9
74
356
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
3.2
8.8
36
120
L89
ICPC
Osteoarthrosis of hip
14.4
8.7
14
10
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
51.1
8.7
10
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.7
8.7
49
196
M03BC51
ATC
orphenadrine, combinations; systemic
2.0
8.6
123
728
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.2
8.5
35
117
N02BE01
ATC
paracetamol; systemic, rectal
2.4
8.5
373
3172
M25.2
ICD-10 Finland
Flail joint
91.8
8.4
9
*
NG1DA
NOMESCO Finland
X-ray of knees
91.8
8.4
9
*
NH3AA, ,
SPAT
3.7
8.4
27
77
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.2
8.4
22
54
WX214
NOMESCO Finland
Plexus blockade at the ankle
+∞
8.4
8
*
7364B
ICD-9 Finland
Other acquired deformities of limbs, Genu valgum or varum (acquired)[GENU VARUM ACQUISITUM]
+∞
8.4
8
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
+∞
8.4
8
*
M22.1
ICD-10 Finland
Recurrent subluxation of patella
+∞
8.4
8
*
J01DB01
ATC
cefalexin; oral
2.1
8.3
345
2851
A02BC03
ATC
lansoprazole; oral
1.9
8.3
123
736
M01AB05
ATC
diclofenac; systemic, rectal
1.8
8.2
268
2045
Z76.0
ICD-10 Finland
Issue of repeat prescription
2.0
8.1
106
606
A02BC02
ATC
pantoprazole; systemic
1.8
8.1
274
2110
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
22.5
8.1
11
5
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
8.0
164
1084
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
3.9
8.0
24
65
M03BC01
ATC
orphenadrine (citrate); systemic
2.0
8.0
98
547
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.8
7.9
18
39
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
7.8
93
513
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
7.8
120
725
M01AH02
ATC
rofecoxib; oral
2.5
7.7
50
214
WX702
NOMESCO Finland
Supraglottic ventilation device
3.3
7.7
30
97
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
3.3
7.7
29
92
L13
ICPC
Hip symptom/complaint
2.2
7.6
69
342
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
18.8
7.6
11
6
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
18.8
7.6
11
6
TNX39
NOMESCO Finland
Other orthopedic bandage, unspecified region
9.1
7.6
15
17
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.3
7.5
17
24
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.7
7.5
24
68
M43.1
ICD-10 Finland
Spondylolisthesis
3.7
7.5
24
68
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.4
7.4
27
84
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
7.3
52
232
B01AF01
ATC
rivaroxaban; oral
2.7
7.3
39
151
M54.4
ICD-10 Finland
Lumbago with sciatica
2.1
7.3
72
369
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
+∞
7.3
7
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.8
7.3
22
60
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
16.1
7.3
11
7
M47.82
ICD-10 Finland
Other spondylosis, cervical region
4.1
7.2
20
51
IHA10
NOMESCO Finland
Structured mapping of problematic alcohol use
30.6
7.2
9
*
M03BX02
ATC
tizanidine; oral
1.7
7.1
261
2024
H01.0
ICD-10 Finland
Blepharitis
2.8
7.0
36
137
G44.2
ICD-10 Finland
Tension-type headache
2.2
7.0
64
319
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
3.3
7.0
26
82
SPAT1202
SPAT
Intra-articular injection
7.7
7.0
15
20
A02BC05
ATC
esomeprazole; systemic
1.7
6.9
165
1131
J02AC01
ATC
fluconazole; systemic
1.7
6.9
182
1284
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.9
6.9
20
53
N02BF01
ATC
gabapentin; oral
2.7
6.8
36
139
UJF32
NOMESCO Finland
Coloscopy
1.9
6.8
102
608
ZXC84
NOMESCO Finland
Bloodless operation space
17.0
6.8
10
6
M77.1
ICD-10 Finland
Lateral epicondylitis
2.7
6.7
37
146
M01AE02
ATC
naproxen; oral, rectal
1.7
6.7
233
1766
NF1DA
NOMESCO Finland
X-ray of hips
22.9
6.7
9
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
6.7
78
426
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.5
6.7
44
190
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.2
6.6
56
270
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
8.9
6.6
13
15
J01FA10
ATC
azithromycin; systemic
1.7
6.6
250
1938
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.0
6.5
74
401
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
70.9
6.4
7
*
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
70.9
6.4
7
*
M54.8
ICD-10 Finland
Other dorsalgia
3.3
6.4
24
76
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.3
6.4
51
240
M54.2
ICD-10 Finland
Cervicalgia
2.6
6.3
38
157
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
+∞
6.3
6
*
NHK68
NOMESCO Finland
Shortening or lengthening osteotomy of ankle or foot
+∞
6.3
6
*
M16.3
ICD-10 Finland
Other dysplastic coxarthrosis
+∞
6.3
6
*
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.9
6.3
30
110
WX213
NOMESCO Finland
Lower leg blockade
27.1
6.2
8
*
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.6
6.2
20
57
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
6.4
6.2
15
24
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
7.8
6.2
13
17
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
10.2
6.1
11
11
TQW40, ,
SPAT
2.8
6.1
30
112
J01DA01
ATC
[U] cefalexin
1.7
6.0
255
2012
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
4.0
6.0
17
44
J01AA02
ATC
doxycycline; systemic
1.8
6.0
322
2706
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
55
156
3.90
17.30
2.8
2.3
0.23
0.24
e6/l
0.02
55
150
214
1422
2.01
11.27
2.3
2.4
—
—
—
0
0
126
689
2.17
11.25
4.8
3.4
1.02
1.02
kg/l
0.18
19
94
144
832
2.10
11.13
4.9
3.4
0.00
0.01
estimate
0.80
47
284
305
2370
2.00
9.46
5.1
3.2
11.00
11.34
mm/h
0.21
291
2160
18
20
9.34
9.11
1.2
1.0
—
—
—
0
0
86
442
2.18
8.77
1.4
1.2
30.09
16.31
iu/ml
0.67
29
138
197
1362
1.83
8.44
11.1
10.3
1.13
1.16
inr
0.37
69
420
217
1572
1.77
7.73
4.4
3.3
0.00
0.00
estimate
-0.00
51
299
318
2584
1.90
7.66
6.9
6.9
78.32
78.12
u/l
0.03
304
2427
195
1390
1.74
7.20
2.8
2.3
80.54
76.94
nmol/l
1.10
190
1250
216
1588
1.73
7.10
5.6
4.6
0.00
0.00
estimate
0.50
49
288
216
1595
1.72
6.94
4.5
3.3
0.00
0.02
estimate
0.80
47
279
176
1232
1.73
6.84
4.6
3.4
—
—
—
0
0
76
409
2.04
6.79
1.3
1.1
11.82
1.30
u/ml
0.75
24
166
21
59
3.69
6.67
1.9
1.8
—
—
—
0
0
150
1016
1.73
6.49
2.2
2.3
58.57
59.16
u/l
0.04
145
937
155
1098
1.65
5.49
3.1
2.9
—
—
—
0
0
226
1759
1.60
5.43
4.5
6.3
9.55
11.09
umol/l
1.51
221
1671
170
1250
1.60
5.09
2.0
1.9
96.01
96.60
pmol/l
0.05
94
613
237
1886
1.58
5.03
9.2
9.1
3.83
4.06
e9/l
1.10
222
1642
180
1351
1.57
4.89
4.3
4.8
35.97
35.85
g/l
0.11
172
1267
378
3400
1.96
4.84
15.6
11.6
18.50
23.98
mg/l
3.42
315
2518
77
480
1.74
4.31
2.8
2.6
4.47
3.95
e6/l
0.17
57
245
260
2155
1.53
4.30
5.2
3.9
—
2831.85
—
0
33
389
3564
2.00
4.25
16.4
13.6
3.93
3.94
mmol/l
0.42
383
3440
103
701
1.62
4.13
1.4
1.8
0.97
1.28
mg/l
0.74
80
530
101
689
1.61
4.00
2.4
2.4
340.20
9319.83
umol/l
4.28
91
611
225
1849
1.46
3.62
5.3
4.2
6.34
6.64
mmol/l
1.47
218
1720
35
180
2.03
3.55
1.5
1.4
—
—
—
0
0
151
1153
1.48
3.53
2.7
3.6
2.36
2.37
mmol/l
0.66
140
1017
361
3276
1.65
3.52
5.7
4.7
1.84
2.29
mu/l
0.64
345
2988
123
910
1.49
3.34
1.7
1.6
1.27
1.31
mmol/l
0.32
104
747
24
109
2.27
3.32
3.5
6.5
1.85
1.51
%
1.25
24
101
350
3172
1.57
3.21
5.6
5.1
38.54
39.25
mmol/mol
1.02
341
2910
9
20
4.57
3.13
1.3
1.3
5.66
5.73
mmol/l
—
9
20
194
1583
1.41
3.08
7.0
6.6
1.22
1.22
mmol/l
0.23
177
1338
178
1434
1.41
3.03
6.9
5.6
1.21
1.22
mmol/l
0.46
172
1300
94
675
1.50
2.92
1.7
1.6
441.67
37679015.05
pmol/l
1.07
79
560
399
3771
1.86
2.70
10.7
8.8
26.75
24.85
u/l
0.76
390
3616
42
253
1.73
2.67
3.5
4.3
62.34
81.70
ng/l
1.19
37
221
31
171
1.88
2.62
7.4
7.3
24.77
24.77
mmol/l
0.00
31
161
361
3335
1.53
2.60
14.2
11.0
83.29
82.45
ml/min/173m2
0.30
319
2704
43
263
1.71
2.60
11.8
7.1
123.21
121.39
g/l
0.31
43
255
104
780
1.44
2.57
2.6
3.2
752.15
1063.40
ng/l
0.92
91
663
15
64
2.39
2.41
1.1
1.5
1.68
0.03
iu/ml
—
6
12
144
1156
1.37
2.39
3.4
3.2
45.21
70.65
ng/l
0.29
90
752
16
71
2.30
2.37
1.2
1.5
—
—
—
0
0
10
33
3.08
2.37
1.3
1.2
—
—
—
0
0
11
40
2.80
2.29
1.4
2.4
31.45
31.02
pg
0.10
11
40
49
322
1.59
2.26
10.7
6.5
12.91
11.99
kpa
0.62
49
307
49
322
1.59
2.26
10.7
6.5
4.97
5.13
kpa
0.73
49
305
37
226
1.70
2.26
1.2
1.5
—
—
—
0
0
49
323
1.58
2.24
10.8
6.5
1.57
1.30
mmol/l
0.27
39
261
108
845
1.37
2.07
2.6
2.9
0.20
0.53
e6/l
2.57
93
626
18
91
2.02
1.98
1.1
1.2
—
—
—
0
0
7
21
3.37
1.97
1.1
2.0
—
—
—
0
0
6
16
3.79
1.94
2.8
2.5
87.73
70.71
ug/l
—
6
16
304
2776
1.33
1.91
5.1
4.0
14.95
14.68
pmol/l
1.22
284
2525
93
722
1.37
1.87
1.4
1.4
—
—
—
0
0
410
3959
1.85
1.80
21.5
17.1
40.10
39.93
%
0.32
384
3700
72
539
1.40
1.79
1.8
1.6
1419.74
1201.92
nmol/l
1.35
62
388
94
737
1.35
1.77
1.5
1.4
21.79
21.09
nmol/l
0.18
88
627
410
3961
1.83
1.77
22.1
17.2
259.44
257.71
e9/l
0.23
405
3827
40
267
1.55
1.76
1.4
1.2
171.29
185.28
iu/ml
0.08
14
108
95
747
1.35
1.76
2.7
2.0
2.94
3.06
mg/l
0.25
88
623
50
352
1.48
1.73
1.8
1.7
—
—
—
0
0
410
3964
1.82
1.72
22.1
17.1
4.43
4.48
e12/l
1.33
403
3831
6
19
3.19
1.66
1.5
1.4
2.37
1.93
mmol/l
—
6
19
375
3561
1.43
1.65
5.1
4.6
2.85
2.88
mmol/l
0.25
364
3281
366
3475
1.37
1.48
4.7
4.1
1.59
1.54
mmol/l
1.06
355
3198
76
594
1.34
1.47
3.0
3.7
66.23
414.91
ng/l
1.94
39
435
42
296
1.46
1.46
3.4
2.2
388.78
371.73
nmol/l
0.24
37
274
53
392
1.40
1.43
2.0
2.4
21.07
23.47
%
0.61
44
345
250
2275
1.24
1.37
3.0
2.9
34.05
45.86
u/l
2.97
243
2128
10
48
2.11
1.28
1.3
1.5
—
—
—
0
0
18
107
1.71
1.28
1.4
2.1
2.18
2.79
g/l
2.24
18
97
352
3344
1.30
1.25
4.3
3.7
1.25
1.25
mmol/l
0.01
340
3064
15
85
1.79
1.24
1.7
1.8
—
—
—
0
0
5
19
2.65
1.22
5.4
2.4
—
—
—
0
0
75
602
1.30
1.21
2.4
3.1
2.46
2.46
mmol/l
0.14
67
535
366
3499
1.32
1.21
4.8
4.1
4.85
4.84
mmol/l
0.05
357
3238
356
3403
1.27
1.09
4.6
4.1
5.73
5.83
mmol/l
0.93
338
3107
18
113
1.62
1.07
2.1
1.6
—
—
—
0
0
97
819
1.24
1.04
1.3
1.3
3.80
2.14
u/ml
0.26
32
186
9
46
1.98
1.04
1.1
1.1
—
—
—
0
0
7
35
2.02
1.00
1.1
1.3
1.98
3.71
ug/l
—
7
28
18
117
1.56
0.95
1.4
2.1
—
—
—
0
0
18
117
1.56
0.95
1.4
2.1
7.26
7.22
g/l
0.04
18
107
18
117
1.56
0.95
1.4
2.1
3.10
3.35
g/l
0.46
18
107
15
93
1.64
0.95
1.1
1.2
—
—
—
0
0
85
721
1.22
0.88
1.6
2.2
—
—
—
0
0
75
631
1.23
0.85
1.4
1.5
—
—
—
0
0
105
915
1.20
0.83
2.0
2.1
415.42
182.92
u/l
0.36
100
864
0
25
0.00
0.79
0.0
1.0
—
67.69
—
0
16
0
25
0.00
0.79
0.0
1.0
—
467.50
—
0
16
241
2261
1.15
0.73
3.0
3.0
—
—
—
0
0
5
26
1.93
0.71
1.6
1.4
—
—
—
0
0
7
42
1.68
0.68
1.4
1.0
—
—
—
0
0
20
146
1.39
0.65
1.9
2.3
38.75
39.03
u/l
0.03
20
136
43
353
1.24
0.63
1.7
2.1
—
—
—
0
0
15
210
0.70
0.62
1.1
1.0
—
—
—
0
0
29
227
1.30
0.62
2.9
2.8
106.14
196.30
ng/l
1.52
23
210
8
51
1.58
0.60
1.1
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
12
80
1.51
0.60
1.2
1.5
1474.25
161.61
e6/l
0.50
12
64
17
123
1.40
0.58
1.2
1.7
—
—
—
0
0
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
6
36
1.68
0.57
3.0
1.3
—
—
—
0
0
19
143
1.34
0.53
17.9
7.0
24.32
24.37
mmol/l
0.03
19
137
35
289
1.23
0.51
2.7
2.8
—
—
—
0
0
12
167
0.71
0.50
1.3
1.7
—
—
—
0
0
37
309
1.22
0.49
1.5
2.0
—
—
—
0
0
21
164
1.29
0.47
1.2
1.4
—
—
—
0
0
12
85
1.42
0.47
1.4
1.2
—
—
—
0
0
31
255
1.23
0.47
5.8
8.4
8.76
8.72
mmol/l
0.01
31
245
7
48
1.47
0.47
1.6
1.5
35.10
25.37
u/l
—
7
43
100
910
1.13
0.46
3.7
3.6
2.81
11.00
mg/mmol
3.48
64
548
12
87
1.39
0.42
1.8
1.7
—
—
—
0
0
56
493
1.16
0.42
2.8
2.6
0.67
1.27
e6/l
1.90
35
257
0
16
0.00
0.41
0.0
1.1
—
356.80
—
0
10
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
55
486
1.15
0.40
1.5
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
7
105
0.66
0.39
1.1
1.4
74.86
309.98
pmol/l
—
7
105
12
89
1.36
0.38
2.6
1.6
1.24
1.21
g/l
0.10
12
84
23
277
0.82
0.36
2.3
2.6
0.55
0.95
ug/l
1.73
13
167
12
90
1.34
0.36
1.6
2.5
9.22
11.58
mg/l
1.18
12
85
5
77
0.65
0.36
1.2
1.3
—
3.02
—
0
5
31
264
1.19
0.36
11.8
5.5
1.06
1.32
mmol/l
1.86
31
256
6
42
1.43
0.35
1.0
1.4
—
—
—
0
0
6
43
1.40
0.35
1.0
1.3
—
—
—
0
0
6
43
1.40
0.35
1.0
1.3
—
—
—
0
0
10
133
0.75
0.34
1.4
1.4
—
—
—
0
0
15
118
1.28
0.34
1.5
2.0
—
—
—
0
0
6
46
1.31
0.33
1.0
1.0
—
—
—
0
0
7
96
0.72
0.31
1.0
1.2
—
—
—
0
0
10
76
1.32
0.28
3.6
2.4
—
—
—
0
0
11
85
1.30
0.28
1.5
2.1
0.00
0.00
g/l
-0.00
11
75
8
66
1.22
0.27
1.0
1.6
—
—
—
0
0
14
114
1.24
0.25
2.2
1.5
256.36
326.27
mu/l
0.79
14
106
7
95
0.73
0.22
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
176.34
—
0
13
19
164
1.17
0.20
4.5
4.3
23.83
24.19
mmol/l
0.23
19
158
13
108
1.21
0.20
1.4
2.1
1.20
2.27
ug/l
0.51
13
97
6
49
1.23
0.20
1.0
1.4
—
—
—
0
0
6
51
1.18
0.19
1.0
1.1
—
—
—
0
0
13
109
1.20
0.19
1.6
1.9
—
—
—
0
0
6
53
1.13
0.18
1.3
1.1
—
—
—
0
0
7
58
1.21
0.18
1.0
1.4
—
—
—
0
0
7
58
1.21
0.18
1.0
1.4
—
—
—
0
0
21
186
1.14
0.17
3.0
3.8
1.12
1.93
mmol/l
0.57
13
144
5
69
0.72
0.17
3.8
6.5
—
439.64
—
0
14
8
70
1.15
0.16
1.5
1.4
—
—
—
0
0
8
73
1.10
0.16
1.0
1.5
—
—
—
0
0
37
342
1.09
0.15
1.6
1.8
—
—
—
0
0
20
178
1.13
0.15
1.3
1.3
—
—
—
0
0
14
161
0.87
0.15
1.6
1.7
—
—
—
0
0
11
129
0.85
0.15
2.5
2.5
11.73
11.44
nmol/l
0.04
11
117
11
93
1.19
0.14
1.4
2.4
33068.26
3606.97
u/l
—
5
42
40
374
1.08
0.13
3.5
4.5
24.45
20.73
%
0.67
11
170
10
86
1.17
0.11
1.4
1.5
—
—
—
0
0
14
156
0.89
0.10
1.4
1.8
2.72
6.30
mg/l
—
8
117
26
242
1.08
0.09
4.4
2.9
65.65
68.48
ml/min/173m2
0.11
12
90
11
97
1.14
0.09
1.5
2.1
0.05
1.60
g/l
1.96
11
86
37
351
1.06
0.09
11.5
5.9
103.89
104.36
mmol/l
0.25
37
351
6
57
1.05
0.08
2.2
2.3
130.33
129.52
g/l
—
6
42
13
144
0.90
0.08
1.3
1.5
—
—
—
0
0
36
342
1.06
0.08
1.6
1.8
—
—
—
0
0
38
362
1.05
0.08
4.1
4.3
3.26
28.21
ug/l
0.75
32
307
7
66
1.06
0.08
1.6
1.5
—
—
—
0
0
8
77
1.04
0.07
1.0
1.4
—
—
—
0
0
8
95
0.84
0.06
1.0
1.1
—
—
—
0
0
48
470
1.02
0.02
3.7
4.5
1.99
2.64
ug/l
0.64
40
423
30
292
1.03
0.02
3.1
4.2
2.72
1.94
mmol/l
0.93
25
231
21
203
1.04
0.01
1.6
1.8
—
—
—
0
0
37
377
0.98
0.01
8.9
5.9
—
—
—
0
0
13
124
1.05
0.00
5.3
2.0
1.47
1.42
g/l
0.08
13
109
10
97
1.03
0.00
1.2
1.0
—
1.48
—
0
10
11
108
1.02
0.00
1.4
2.2
8.87
10.61
g/l
0.76
11
98
32
317
1.01
0.00
2.2
2.3
27.56
40.38
u/l
1.10
27
264
5
51
0.98
0.00
1.6
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
9.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
7
79
0.88
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
7.70
—
0
5
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
7
79
0.88
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
79
0.88
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
79
0.88
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_VARUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_VARUS | 0.983 [0.85, 1.14] | 0.816 |
| Birth year | 0.994 [0.99, 1.0] | 0.151 |
During the follow-up period (1.1.1998 — 31.12.2019), 249 out of 2081 females with M13_VARUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_VARUS | 0.887 [0.73, 1.08] | 0.242 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 763 males with M13_VARUS died.
Mortality risk
Mortality risk for people of age
years, who have M13_VARUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.074% | 0.182% |
| 5 | 0.453% | 1.075% |
| 10 | 1.299% | 2.474% |
| 15 | 2.626% | 4.632% |
| 20 | 4.587% | 7.824% |
Relationships between endpoints
↥Index endpoint: M13_VARUS – Varus deformity, not elsewhere classified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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