No definition available.
Localized skin eruption due to drugs and medicaments
LOCALIZED_SKIN_ERUPT_DRUGS_MEDICAM
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
401 |
4. Check minimum number of eventsNone |
401 |
5. Include endpointsNone |
401 |
6. Filter based on genotype QC (FinnGen only) |
401 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Localized skin eruption due to drugs and medicaments
based on the number of shared cases.
Similar with more cases:
- Dermatitis due to substances taken internally
- Dermatitis and eczema
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2626 | 1498 | 1115 |
| Only index persons | 2347 | 1368 | 979 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 51.43 | 54.02 | 47.91 |
| Only index persons | 52.21 | 54.10 | 49.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 401 | 257 | 144 |
| Unadjusted period prevalence (%) | 0.08 | 0.09 | 0.06 |
| Median age at first event (years) | 54.76 | 52.84 | 58.19 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 347
- Matched controls
- 3469
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L27.1
ICD-10 Finland
Localized skin eruption due to drugs and medicaments
4503599627370496.0
323.0
346
*
H02AB06
ATC
prednisolone; systemic
4.6
38.8
239
1126
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.3
23.1
77
178
XQ800
NOMESCO Finland
Prick test
4.8
17.9
63
152
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.5
17.9
99
359
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.4
15.1
57
147
R06AE07
ATC
cetirizine; oral
2.5
14.5
184
1089
D07AC01
ATC
betamethasone; topical
2.5
14.3
149
792
E0000UV
ATC
NA
2.4
13.5
169
982
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
12.9
167
981
XQ820
NOMESCO Finland
Exposure to medicinal substance
72.5
12.7
14
*
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
13.1
12.3
21
17
H02AB02
ATC
dexamethasone; systemic
3.6
11.9
56
176
N02AX02
ATC
tramadol; systemic, rectal
2.2
11.3
162
976
R06AX27
ATC
desloratadine; oral
2.4
11.0
118
616
R06AE09
ATC
levocetirizine; oral
2.8
10.0
68
275
J01AA02
ATC
doxycycline; systemic
2.3
9.7
274
2155
XQ802
NOMESCO Finland
Epicutan test
4.5
9.7
34
82
A03FA01
ATC
metoclopramide; systemic, rectal
2.4
9.7
89
429
A02BC02
ATC
pantoprazole; systemic
2.1
9.5
231
1696
J01MA02
ATC
ciprofloxacin; systemic
2.1
9.5
145
879
J01DB01
ATC
cefalexin; oral
2.4
9.2
296
2441
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
8.9
115
645
A02BC05
ATC
esomeprazole; systemic
2.0
8.8
153
969
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.5
8.8
77
359
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.2
8.7
48
168
J01FF01
ATC
clindamycin; systemic
2.1
8.1
105
585
UJF32
NOMESCO Finland
Coloscopy
2.1
7.7
101
564
XQ801
NOMESCO Finland
Intracutantest
18.9
7.6
11
6
R50.9
ICD-10 Finland
Fever, unspecified
2.5
7.6
62
277
UDC00
NOMESCO Finland
Ear microscopy
3.3
7.6
38
126
XX3DW
NOMESCO Finland
Time consuming IT work
3.0
7.4
42
152
L03AA13
ATC
pegfilgrastim; parenteral
4.8
7.3
23
50
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
7.2
107
631
J01MA12
ATC
levofloxacin; systemic
2.2
7.1
75
380
A04AA02
ATC
granisetron; systemic, transdermal
3.7
7.1
30
87
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
7.0
140
915
T78.4
ICD-10 Finland
Allergy, unspecified
4.0
6.9
26
68
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.5
6.9
53
230
J02AC01
ATC
fluconazole; systemic
1.9
6.9
152
1027
J01FA09
ATC
clarithromycin; systemic
1.9
6.6
122
771
L50.9
ICD-10 Finland
Urticaria, unspecified
4.2
6.5
23
57
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.6
6.4
47
198
N03AX16
ATC
pregabalin; oral
2.0
6.4
90
516
K12.00
ICD-10 Finland
Recurrent oral aphthae
9.5
6.3
12
13
ZX120
NOMESCO Finland
Intravenous
2.8
6.3
40
156
D07AD01
ATC
clobetasol; topical
2.2
6.2
63
313
N48.1
ICD-10 Finland
Balanoposthitis
5.9
6.2
16
28
D07AC13
ATC
mometasone; topical
1.9
6.2
106
652
D70.82
ICD-10 Finland
Drug-induced neutropenia
7.9
6.2
13
17
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.0
6.1
23
61
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
6.1
105
645
L50.0
ICD-10 Finland
Allergic urticaria
5.7
6.1
16
29
J01DA01
ATC
[U] cefalexin; systemic
1.8
6.1
216
1678
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
231
1397
2.54
18.47
5.6
5.7
1.2
1.2
mmol/l
0.39
212
1276
286
1922
2.70
18.17
14.0
9.4
4.2
4.0
e9/l
0.65
262
1694
243
1550
2.44
16.64
6.9
6.6
1.2
1.2
mmol/l
0.12
195
1315
333
2537
2.84
14.43
12.4
7.5
79.9
77.7
u/l
0.39
316
2364
209
1302
2.26
14.38
6.4
4.8
35.4
35.9
g/l
0.60
196
1221
248
1719
2.16
12.34
9.0
6.2
10.8
10.6
umol/l
0.08
235
1630
316
2483
2.29
10.50
6.2
4.1
13.6
11.3
mm/h
1.74
296
2278
92
481
2.18
9.08
3.9
3.7
0.8
0.8
mmol/l
0.09
87
455
151
947
1.95
9.08
2.1
2.1
207.7
265.3
u/l
0.25
141
893
160
1028
1.93
8.92
3.1
2.4
54.5
55.5
u/l
0.14
137
949
113
648
2.04
8.72
1.9
1.7
447.5
9141203.0
pmol/l
0.50
94
547
24
62
4.05
8.55
2.1
2.4
17.8
15.7
%
—
7
25
89
470
2.15
8.53
1.7
2.1
29.3
29.6
s
0.18
89
456
280
2187
1.93
8.25
6.1
4.3
116.2
201.6
e6/l
—
6
40
19
42
4.70
8.20
1.3
1.7
90.6
89.6
%
0.26
19
42
75
381
2.19
7.88
4.8
5.6
1.0
1.0
mmol/l
0.37
69
355
60
279
2.35
7.77
2.7
2.4
0.2
0.2
g/l
0.36
55
263
249
1894
1.83
7.73
5.7
4.5
6.5
6.6
mmol/l
0.42
240
1756
85
458
2.09
7.67
2.5
2.1
2.4
2.4
g/l
0.37
80
423
194
1381
1.78
7.42
2.8
2.3
78.1
76.0
nmol/l
0.42
176
1235
95
542
1.99
7.30
1.7
1.7
1321.9
1188.6
nmol/l
0.69
70
404
101
589
1.96
7.29
1.4
1.3
16.9
34.3
iu/ml
2.28
37
192
208
1526
1.75
7.05
3.4
2.6
121.4
104.2
ug/l
0.41
191
1409
65
328
2.17
6.91
3.7
3.3
—
—
—
0
0
158
1076
1.77
6.91
5.6
3.2
2.3
2.4
mmol/l
1.57
141
938
375
3340
2.89
6.90
24.5
13.4
18.9
21.9
mg/l
1.41
337
2619
44
188
2.51
6.84
3.4
3.5
1.5
1.2
mmol/l
0.22
29
139
131
847
1.81
6.80
2.9
3.0
1156.8
1097.6
ng/l
0.09
110
719
168
1172
1.75
6.71
4.3
3.0
—
—
—
0
0
77
422
2.02
6.58
2.7
2.2
21.6
23.3
%
0.48
67
362
45
198
2.43
6.57
3.5
3.5
5.0
5.0
kpa
0.05
40
185
22
65
3.52
6.51
2.5
3.6
4.7
4.6
e9/l
0.08
22
65
217
1636
1.71
6.47
4.9
3.6
0.0
0.0
estimate
0.00
56
336
48
221
2.33
6.34
1.5
1.6
—
—
—
0
0
168
1186
1.72
6.34
4.4
3.5
20.4
36.8
ng/l
2.01
120
788
85
492
1.92
6.19
2.7
2.1
12.7
13.6
umol/l
0.51
80
452
209
1575
1.68
6.11
4.5
4.0
—
—
—
0
0
22
68
3.37
6.09
3.4
4.0
59.4
58.1
%
0.15
22
68
216
1643
1.68
6.09
6.4
4.9
0.0
0.0
estimate
0.00
58
339
218
1667
1.67
5.98
4.9
3.6
0.0
0.0
estimate
0.50
57
331
83
486
1.89
5.82
2.1
1.9
—
—
—
0
0
305
2563
1.79
5.82
5.3
4.0
14.7
14.6
pmol/l
0.23
283
2318
52
259
2.16
5.70
4.2
3.9
1.2
1.2
mmol/l
1.14
45
232
174
1267
1.66
5.68
2.1
1.9
97.9
96.5
pmol/l
0.13
97
644
132
898
1.70
5.56
5.4
3.9
0.0
0.0
estimate
0.00
56
335
134
917
1.69
5.51
3.8
2.8
0.5
0.4
e6/l
0.10
108
666
11
22
5.11
5.29
2.4
2.7
—
—
—
0
0
271
2239
1.65
5.12
3.9
3.2
48.4
44.9
u/l
0.39
252
2105
92
580
1.76
5.03
1.4
1.3
51.7
11.9
u/ml
0.39
34
234
17
51
3.44
4.94
1.6
1.5
—
—
—
0
0
119
810
1.67
4.91
3.0
2.0
3.1
3.1
mg/l
0.01
99
695
112
754
1.67
4.81
1.8
1.8
0.9
1.2
mg/l
0.59
81
591
123
849
1.65
4.79
3.0
2.7
6506.4
6499.8
umol/l
0.00
105
730
173
1309
1.57
4.55
5.3
3.7
—
—
—
0
0
59
334
1.90
4.55
3.7
4.4
219.9
245.1
u/l
1.37
54
317
18
62
2.99
4.22
1.6
1.7
—
—
—
0
0
36
176
2.15
4.15
1.8
1.3
—
—
—
0
0
25
104
2.50
4.14
1.2
1.2
—
—
—
0
0
27
117
2.40
4.11
1.5
2.4
—
—
—
0
0
13
37
3.60
4.08
1.1
1.3
—
—
—
0
0
7
7
10.15
4.02
2.3
2.0
—
—
—
0
0
118
837
1.58
4.02
1.5
1.3
1.7
1.3
u/ml
0.22
35
230
21
83
2.61
3.86
1.1
1.3
—
—
—
0
0
107
751
1.58
3.79
1.8
1.5
20.9
20.9
nmol/l
0.01
95
644
37
191
2.03
3.72
1.5
1.3
—
—
—
0
0
55
326
1.80
3.67
6.2
7.5
1.9
1.2
mmol/l
0.70
45
269
24
104
2.39
3.67
1.2
1.2
—
—
—
0
0
11
30
3.74
3.66
1.7
1.5
—
—
—
0
0
13
40
3.33
3.65
1.6
1.5
—
—
—
0
0
340
3072
1.70
3.61
6.4
4.8
1.9
1.9
mu/l
0.20
316
2808
55
330
1.77
3.53
2.1
1.9
—
—
—
0
0
13
41
3.24
3.52
1.2
1.2
—
—
—
0
0
265
2270
1.49
3.51
3.6
3.2
—
—
—
0
0
107
771
1.53
3.33
2.9
2.2
—
—
—
0
0
21
90
2.41
3.30
2.1
1.5
—
—
—
0
0
21
90
2.41
3.30
1.5
1.6
—
—
—
0
0
145
1115
1.47
3.29
3.4
3.3
29.0
31.8
u/l
0.68
135
1067
53
322
1.74
3.26
6.9
4.0
12.4
41.0
ug/l
0.58
44
266
44
253
1.83
3.25
3.0
4.3
2.0
1.9
mmol/l
0.06
34
197
51
310
1.74
3.14
2.0
2.2
30.0
31.1
u/l
0.13
43
255
20
86
2.40
3.13
1.5
1.6
—
—
—
0
0
53
328
1.71
3.06
2.0
1.8
—
—
—
0
0
376
3551
1.94
2.71
17.5
10.2
24.8
25.7
u/l
0.63
367
3423
6
10
6.07
2.70
1.2
1.0
5.2
6.3
umol/l
—
6
10
342
3151
1.58
2.70
21.5
12.2
83.9
83.9
ml/min/173m2
0.00
300
2564
21
100
2.16
2.64
1.4
2.0
8.6
11.1
mg/l
0.89
21
94
19
87
2.24
2.61
1.8
1.4
—
—
—
0
0
8
20
4.06
2.58
6.6
3.2
—
—
—
0
0
328
3004
1.50
2.56
6.4
5.6
39.3
39.5
mmol/mol
0.14
296
2803
28
152
1.91
2.50
1.1
1.4
19.1
25.2
iu/l
0.42
23
131
95
706
1.45
2.49
1.8
1.5
—
—
—
0
0
19
89
2.19
2.49
3.9
4.0
251.5
124.4
mg/l
0.22
13
74
19
89
2.19
2.49
3.9
4.0
20.2
29.2
mg/l
0.96
14
73
22
110
2.06
2.46
1.9
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
18
83
2.22
2.45
2.2
2.6
0.5
0.3
u/ml
0.53
12
46
16
70
2.34
2.44
1.4
1.8
—
—
—
0
0
16
70
2.34
2.44
2.9
2.8
9.3
8.5
kpa
1.38
16
63
6
12
5.06
2.41
1.5
1.3
—
—
—
0
0
42
262
1.67
2.38
1.5
1.3
116.4
159.3
iu/ml
0.20
15
108
19
91
2.14
2.37
1.2
1.3
—
—
—
0
0
20
98
2.10
2.36
3.4
3.1
—
—
—
0
0
75
538
1.48
2.35
3.3
2.5
1.1
0.9
e6/l
0.20
43
288
332
3065
1.48
2.32
20.8
14.1
39.5
40.0
%
0.58
231
2304
7
18
3.94
2.26
1.6
1.7
—
—
—
0
0
13
54
2.45
2.22
1.1
1.3
—
—
—
0
0
13
54
2.45
2.22
1.1
1.3
—
—
—
0
0
7
19
3.73
2.16
1.7
1.6
—
—
—
0
0
21
110
1.96
2.10
4.3
2.0
—
—
—
0
0
37
233
1.65
2.05
3.1
3.6
72.0
71.4
ng/l
0.02
30
209
10
38
2.67
2.02
2.0
1.3
—
—
—
0
0
69
503
1.45
2.00
3.5
2.7
4.4
2.6
e6/l
0.79
38
256
16
77
2.12
1.99
1.3
1.2
—
—
—
0
0
7
21
3.37
1.97
1.6
1.7
—
—
—
0
0
59
421
1.47
1.91
1.7
1.8
1.5
1.5
%
0.01
48
369
10
40
2.54
1.85
1.3
1.9
—
—
—
0
0
5
12
4.20
1.83
1.0
1.1
—
—
—
0
0
25
147
1.75
1.78
3.6
2.5
1106.8
3751.5
u/l
—
9
59
26
155
1.72
1.77
2.0
1.6
—
—
—
0
0
77
587
1.39
1.74
3.5
3.5
363.7
295.6
ng/l
0.08
56
438
5
13
3.88
1.72
1.0
1.9
—
—
—
0
0
5
13
3.88
1.72
1.0
1.9
—
—
—
0
0
10
42
2.42
1.69
1.7
1.7
—
—
—
0
0
341
3217
1.40
1.62
5.4
4.4
5.9
5.9
mmol/l
0.15
313
2957
5
14
3.60
1.62
2.0
2.1
762.8
871.9
u/ml
—
5
14
111
911
1.30
1.54
1.6
1.7
1.4
1.3
mmol/l
0.15
87
767
11
51
2.19
1.52
1.8
2.0
4.2
83.7
u/ml
0.48
11
46
13
65
2.03
1.50
2.1
6.9
—
413.8
—
0
12
10
46
2.20
1.41
1.7
1.7
—
—
—
0
0
7
29
2.44
1.40
2.9
2.1
0.2
0.2
e9/l
—
7
24
11
53
2.11
1.39
1.6
1.7
—
—
—
0
0
6
23
2.63
1.37
1.2
1.0
—
—
—
0
0
10
47
2.16
1.34
1.1
1.1
—
—
—
0
0
10
47
2.16
1.34
1.0
1.1
—
—
—
0
0
36
254
1.46
1.27
4.0
2.5
58.7
67.1
ml/min/173m2
0.62
15
103
76
608
1.31
1.27
1.8
1.5
—
—
—
0
0
6
25
2.42
1.25
1.3
1.0
—
—
—
0
0
6
25
2.42
1.25
1.3
1.2
—
—
—
0
0
60
465
1.34
1.24
2.6
2.2
—
—
—
0
0
20
124
1.65
1.23
2.1
2.0
—
—
—
0
0
13
72
1.83
1.16
1.2
1.2
—
—
—
0
0
17
103
1.68
1.14
1.2
3.0
100.8
91.9
%
0.84
12
98
7
30
2.36
1.13
2.7
2.1
739.7
478.9
e6/l
—
7
24
7
30
2.36
1.13
1.7
2.1
—
—
—
0
0
28
194
1.48
1.10
1.1
1.0
—
—
—
0
0
51
394
1.34
1.09
5.7
4.4
32.3
32.0
%
0.06
41
262
54
421
1.33
1.09
2.6
2.0
—
—
—
0
0
11
59
1.89
1.08
1.6
1.6
—
—
—
0
0
10
52
1.95
1.07
1.2
1.3
—
—
—
0
0
7
33
2.14
1.06
1.4
2.1
—
—
—
0
0
7
33
2.14
1.06
1.1
1.2
—
—
—
0
0
18
115
1.59
1.01
1.9
1.8
—
—
—
0
0
13
76
1.73
1.00
1.2
1.4
—
—
—
0
0
48
376
1.31
0.95
31.0
19.0
1.1
1.2
inr
—
5
53
18
118
1.55
0.92
1.6
1.7
—
—
—
0
0
35
263
1.36
0.91
2.8
2.0
—
—
—
0
0
6
29
2.08
0.89
1.2
1.6
—
—
—
0
0
13
81
1.63
0.82
1.4
1.3
—
—
—
0
0
13
81
1.63
0.82
1.1
1.2
—
35.9
—
0
9
100
871
1.20
0.81
5.8
4.8
2.3
2.5
ug/l
0.19
83
779
6
33
1.83
0.79
1.5
1.8
—
—
—
0
0
6
33
1.83
0.79
1.5
1.8
—
—
—
0
0
6
33
1.83
0.79
1.5
1.8
—
—
—
0
0
327
3148
1.21
0.76
4.5
3.9
1.3
1.3
mmol/l
0.54
298
2911
46
372
1.27
0.75
11.6
6.3
—
—
—
0
0
339
3278
1.22
0.73
4.9
4.3
4.7
4.7
mmol/l
0.13
312
3050
9
56
1.62
0.73
1.1
1.1
—
—
—
0
0
7
40
1.76
0.71
1.0
1.5
—
—
—
0
0
28
213
1.34
0.70
2.9
1.9
—
—
—
0
0
7
41
1.72
0.70
1.1
1.5
—
—
—
0
0
7
41
1.72
0.70
1.1
1.5
—
—
—
0
0
7
41
1.72
0.70
1.1
1.5
—
—
—
0
0
7
41
1.72
0.70
1.1
1.5
—
—
—
0
0
7
42
1.68
0.68
1.0
1.1
—
—
—
0
0
7
42
1.68
0.68
1.1
1.5
—
—
—
0
0
5
28
1.80
0.66
1.0
1.2
—
—
—
0
0
5
29
1.73
0.64
1.2
2.8
—
—
—
0
0
5
30
1.67
0.61
1.0
1.2
—
—
—
0
0
8
50
1.61
0.61
3.8
1.9
—
—
—
0
0
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
336
3262
1.19
0.59
5.0
4.3
1.5
1.5
mmol/l
0.30
307
3021
8
55
1.46
0.56
1.9
1.4
—
—
—
0
0
6
37
1.63
0.55
1.2
1.1
1.7
1.4
g/l
—
6
32
18
134
1.36
0.54
3.3
3.6
45.0
48.3
%
0.23
18
134
18
134
1.36
0.54
5.7
5.0
3.4
1.5
%
0.91
18
123
342
3337
1.17
0.49
5.4
4.8
2.7
2.8
mmol/l
0.53
312
3082
7
109
0.64
0.49
1.7
1.4
—
—
—
0
0
7
109
0.64
0.49
1.7
1.4
—
—
—
0
0
7
109
0.64
0.49
1.6
1.4
—
—
—
0
0
7
109
0.64
0.49
1.6
1.4
—
—
—
0
0
23
182
1.28
0.47
3.7
2.6
0.2
0.1
e6/l
0.23
23
173
8
120
0.66
0.46
1.8
1.5
—
—
—
0
0
5
31
1.62
0.43
1.2
1.4
—
—
—
0
0
16
206
0.77
0.42
1.7
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
16
123
1.31
0.41
1.3
1.5
—
—
—
0
0
12
88
1.37
0.40
1.3
1.1
—
—
—
0
0
15
117
1.29
0.35
2.6
1.7
—
—
—
0
0
6
89
0.67
0.33
1.7
1.8
—
—
—
0
0
6
47
1.28
0.32
1.0
1.4
6.8
7.3
mmol/l
—
6
32
28
322
0.86
0.28
2.2
1.7
—
—
—
0
0
8
65
1.24
0.27
1.7
1.5
—
—
—
0
0
11
86
1.29
0.26
1.2
1.2
—
—
—
0
0
5
39
1.29
0.23
1.4
1.1
—
—
—
0
0
17
144
1.19
0.22
3.1
2.7
1.3
1.2
%
0.40
17
144
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
6
49
1.23
0.20
1.3
1.2
—
—
—
0
0
17
148
1.16
0.17
1.5
1.5
2.2
3.1
mg/l
—
10
104
14
120
1.17
0.16
1.2
1.5
177.0
265.6
miu/ml
—
5
64
8
70
1.15
0.16
2.4
1.3
—
—
—
0
0
74
715
1.04
0.09
4.6
4.4
24.5
20.7
%
1.44
38
332
51
516
0.99
0.00
3.4
3.0
0.8
0.7
ug/l
0.05
36
332
12
123
0.97
0.00
1.4
1.4
—
—
—
0
0
5
52
0.96
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
7
73
0.96
0.00
1.4
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
52.4
—
0
5
0
7
0.00
0.00
0.0
1.0
—
22.1
—
0
7
9
98
0.92
0.00
1.3
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
2.9
—
53.5
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint LOCALIZED_SKIN_ERUPT_DRUGS_MEDICAM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| LOCALIZED_SKIN_ERUPT_DRUGS_MEDICAM | 1.557 [1.26, 1.93] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.626 |
During the follow-up period (1.1.1998 — 31.12.2019), 246 out of 1248 females with LOCALIZED_SKIN_ERUPT_DRUGS_MEDICAM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| LOCALIZED_SKIN_ERUPT_DRUGS_MEDICAM | 1.561 [1.26, 1.93] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.027 |
During the follow-up period (1.1.1998 — 31.12.2019), 181 out of 969 males with LOCALIZED_SKIN_ERUPT_DRUGS_MEDICAM died.
Mortality risk
Mortality risk for people of age
years, who have LOCALIZED_SKIN_ERUPT_DRUGS_MEDICAM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.143% | 0.415% |
| 5 | 1.089% | 2.227% |
| 10 | 2.717% | 5.267% |
| 15 | 4.883% | 9.734% |
| 20 | 8.541% | 15.853% |
Relationships between endpoints
↥Index endpoint: LOCALIZED_SKIN_ERUPT_DRUGS_MEDICAM – Localized skin eruption due to drugs and medicaments
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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