No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
244 |
4. Check minimum number of eventsNone |
244 |
5. Include endpointsNone |
244 |
6. Filter based on genotype QC (FinnGen only) |
236 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Osteochondrosis of ankle, juvenile
based on the number of shared cases.
Similar with more cases:
- Juvenile osteochondrosis
- Chondropathies
- Other disorders of bone
- Osteopathies and chondropathies
- Diseases of the musculoskeletal system and connective tissue
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 236 | 172 | 64 |
| Unadjusted period prevalence (%) | 0.05 | 0.06 | 0.03 |
| Median age at first event (years) | 14.93 | 14.54 | 15.98 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 244
- Matched controls
- 2440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M92.6
ICD-10 Finland
Juvenile osteochondrosis of tarsus
+∞
288.1
216
*
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
65.8
99.6
56
11
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
54.4
35.0
41
9
7325X
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of foot
+∞
29.8
28
*
M79.6
ICD-10 Finland
Pain in limb
3.0
15.8
126
643
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
5.9
12.9
24
44
NHF25
NOMESCO Finland
Operation for debridement of ankle joint, arthroscopic
36.9
11.4
14
*
M25.5
ICD-10 Finland
Pain in joint
2.4
9.6
91
481
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
9.1
97
537
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
28.7
8.6
11
*
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
9.4
8.2
16
18
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
11.3
7.9
14
13
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.5
7.6
27
83
M93.2
ICD-10 Finland
Osteochondritis dissecans
82.5
7.5
8
*
N02BE01
ATC
paracetamol; systemic, rectal
2.8
7.1
211
1706
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.3
7.0
28
93
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
6.8
6.8
16
25
M01AH05
ATC
etoricoxib; oral
2.0
6.7
134
920
M85.8
ICD-10 Finland
Other specified disorders of bone density and structure
71.6
6.5
7
*
NHF30
NOMESCO Finland
Fixation of loose fragment from ankle joint
+∞
6.3
6
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.5
6.1
43
194
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
78
492
1.86
4.60
2.2
2.4
65.86
55.21
u/l
0.32
71
456
30
155
2.07
3.11
1.5
1.5
402.84
309.75
mu/l
0.31
25
136
26
128
2.15
3.05
1.3
1.2
320.56
358.88
u/ml
0.06
26
118
74
522
1.60
2.74
2.9
3.3
0.00
0.00
estimate
0.50
30
201
44
273
1.75
2.65
1.4
1.5
436.53
27801265.56
pmol/l
0.50
38
241
5
7
7.26
2.56
1.0
4.3
21.78
12.63
ug/l
—
5
7
5
8
6.35
2.38
2.0
1.4
232.60
201.25
u/l
—
5
8
149
1257
1.48
2.27
6.0
5.9
71.87
76.08
u/l
0.74
139
1178
201
1810
1.63
2.21
9.6
10.0
139.35
139.62
mmol/l
1.06
196
1740
41
263
1.67
2.19
3.2
2.5
1525.03
2762.57
u/l
0.33
11
113
8
26
3.15
2.03
1.3
1.1
—
—
—
0
0
8
27
3.03
1.95
1.4
1.4
12.54
13.10
%
—
8
27
46
316
1.56
1.88
3.1
2.8
324.51
6872.53
umol/l
1.50
41
287
199
1814
1.53
1.79
9.8
10.0
3.94
3.89
mmol/l
1.96
194
1740
6
18
3.39
1.75
1.5
1.2
—
—
—
0
0
6
20
3.05
1.59
1.0
1.1
—
—
—
0
0
96
788
1.36
1.51
4.8
5.2
9.52
10.13
umol/l
0.42
90
730
213
1992
1.55
1.46
11.3
9.6
17.74
19.67
mg/l
0.39
164
1468
182
1655
1.39
1.44
3.1
3.1
5.88
5.53
mmol/l
1.41
162
1515
112
950
1.33
1.40
4.0
4.7
6.14
6.14
mmol/l
0.00
104
830
158
1416
1.33
1.31
4.2
3.7
37.68
37.11
mmol/mol
0.32
149
1335
6
25
2.43
1.25
1.0
1.0
—
—
—
0
0
5
19
2.66
1.22
1.2
1.2
—
—
—
0
0
214
2020
1.48
1.21
8.5
7.6
25.63
25.11
u/l
0.17
207
1942
193
1795
1.36
1.15
5.7
4.5
1.80
1.78
mu/l
0.09
185
1673
148
1330
1.29
1.12
3.9
3.4
8.68
8.43
mm/h
0.12
139
1233
16
97
1.70
1.09
2.0
2.5
1.23
1.23
mmol/l
0.02
16
79
89
754
1.28
1.06
2.0
1.8
—
—
—
0
0
30
215
1.45
1.04
1.7
1.8
—
—
—
0
0
7
34
2.09
1.03
1.0
1.2
—
—
—
0
0
51
403
1.34
1.01
1.5
2.0
1.04
0.79
mg/l
0.44
36
282
168
1545
1.28
1.00
5.0
3.9
14.34
14.53
pmol/l
0.44
156
1399
64
525
1.30
0.97
6.3
7.3
0.99
1.15
inr
4.54
20
199
180
1673
1.29
0.96
8.0
8.2
96.73
98.89
ml/min/173m2
0.68
140
1283
13
206
0.61
0.94
1.4
1.8
—
—
—
0
0
110
971
1.24
0.91
3.6
4.5
0.00
0.00
estimate
-0.00
32
203
234
2273
1.72
0.88
15.5
14.3
40.18
40.37
%
0.18
222
2171
110
975
1.23
0.86
3.1
3.2
0.00
0.00
estimate
0.50
32
207
88
764
1.24
0.83
2.9
3.1
—
—
—
0
0
234
2277
1.68
0.82
15.5
14.2
4.60
4.56
e12/l
0.83
229
2217
65
547
1.26
0.81
2.8
3.0
—
—
—
0
0
198
1879
1.29
0.79
3.8
4.0
—
—
—
0
0
0
28
0.00
0.76
0.0
4.2
—
8.42
—
0
28
110
985
1.21
0.76
3.1
3.2
0.00
0.00
estimate
-0.00
31
198
9
55
1.66
0.74
1.3
2.3
—
—
—
0
0
25
186
1.38
0.73
1.3
1.6
—
—
—
0
0
59
498
1.24
0.71
3.4
2.6
15.67
23.13
ng/l
0.67
27
218
20
147
1.39
0.64
1.7
1.6
—
—
—
0
0
78
687
1.20
0.63
2.5
2.3
—
—
—
0
0
21
157
1.37
0.61
5.6
5.3
—
—
—
0
0
8
54
1.50
0.58
1.4
2.2
—
—
—
0
0
38
314
1.25
0.56
1.2
1.2
1.58
5.59
u/ml
1.47
15
125
6
37
1.64
0.56
1.2
1.4
—
—
—
0
0
12
82
1.49
0.55
1.8
1.4
—
—
—
0
0
14
192
0.71
0.54
1.6
1.4
—
—
—
0
0
14
192
0.71
0.54
1.6
1.4
—
—
—
0
0
14
192
0.71
0.54
1.6
1.4
—
—
—
0
0
39
325
1.24
0.54
1.3
1.2
11.91
21.67
iu/ml
—
10
90
14
191
0.72
0.53
1.6
1.4
—
—
—
0
0
10
67
1.51
0.50
1.0
1.2
—
—
—
0
0
10
67
1.51
0.50
1.0
1.2
—
—
—
0
0
15
110
1.39
0.50
5.7
12.7
1.40
0.68
mmol/l
—
10
83
97
886
1.16
0.49
2.4
2.6
—
—
—
0
0
7
46
1.54
0.48
1.9
3.7
54.49
44.79
%
—
7
46
16
210
0.75
0.48
1.6
1.5
—
—
—
0
0
74
667
1.16
0.45
4.3
7.4
1.22
1.22
mmol/l
0.21
61
579
82
747
1.15
0.43
2.6
2.4
—
—
—
0
0
46
401
1.18
0.42
1.9
1.8
—
—
—
0
0
36
307
1.20
0.41
1.8
1.7
1.46
1.35
%
0.39
31
283
18
141
1.30
0.41
3.7
2.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
50
441
1.17
0.40
2.8
2.8
0.06
0.25
e6/l
3.51
38
334
5
35
1.44
0.39
1.6
1.7
—
—
—
0
0
51
453
1.16
0.38
2.1
2.1
3.36
2.61
mg/l
1.18
44
382
5
37
1.36
0.37
2.2
3.3
57.80
55.62
%
—
5
37
9
70
1.30
0.37
2.2
1.5
—
—
—
0
0
34
294
1.18
0.35
5.0
3.7
12.65
14.56
mg/mmol
0.08
25
198
11
84
1.32
0.30
1.3
1.4
—
—
—
0
0
18
148
1.23
0.30
1.8
1.6
—
—
—
0
0
13
162
0.79
0.29
1.5
2.4
23.46
28.95
u/l
2.27
13
139
24
205
1.19
0.28
1.1
1.3
247.48
139.81
iu/ml
0.46
13
80
20
236
0.83
0.28
2.6
2.8
4.27
4.10
e6/l
0.03
11
124
20
168
1.21
0.28
1.3
1.7
—
—
—
0
0
139
1334
1.10
0.27
3.1
2.9
35.56
32.26
u/l
0.41
134
1280
9
74
1.22
0.25
1.7
2.1
—
—
—
0
0
175
1702
1.10
0.24
3.5
3.3
2.81
2.78
mmol/l
0.21
164
1597
21
243
0.85
0.24
1.6
1.4
—
—
—
0
0
22
253
0.86
0.24
1.3
1.4
—
—
—
0
0
13
106
1.24
0.23
1.3
1.7
—
—
—
0
0
69
646
1.09
0.23
1.3
1.4
0.79
1.54
u/ml
1.26
22
157
28
249
1.14
0.22
2.5
2.6
1.42
0.90
e6/l
0.33
19
135
0
11
0.00
0.21
0.0
1.0
—
0.29
—
0
11
0
10
0.00
0.21
0.0
4.7
—
—
—
0
0
0
10
0.00
0.21
0.0
3.6
—
995.70
—
0
10
0
10
0.00
0.21
0.0
3.6
—
174.57
—
0
10
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
11
134
0.81
0.21
1.5
2.1
—
—
—
0
0
23
202
1.15
0.21
1.8
1.6
1276.84
1113.12
nmol/l
0.26
18
151
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
6
48
1.26
0.20
1.8
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
7
60
1.17
0.18
10.1
10.9
0.89
1.24
%
—
7
60
7
60
1.17
0.18
10.1
10.9
0.64
0.69
%
—
7
60
5
66
0.75
0.17
1.0
2.0
55.00
38.75
u/l
—
5
61
17
149
1.15
0.16
1.4
1.5
—
—
—
0
0
17
150
1.14
0.15
1.1
1.4
188.86
266.15
miu/ml
—
7
73
7
88
0.79
0.15
1.3
1.5
—
—
—
0
0
35
377
0.92
0.15
1.6
1.5
—
—
—
0
0
23
253
0.90
0.14
2.4
2.9
8.16
211.52
ng/l
—
8
130
10
84
1.20
0.14
1.6
1.2
—
—
—
0
0
11
95
1.17
0.12
1.6
2.7
4.08
6.89
umol/l
—
5
75
10
87
1.16
0.09
1.3
1.3
—
—
—
0
0
42
400
1.06
0.09
2.1
2.2
—
—
—
0
0
6
54
1.11
0.09
1.2
2.1
—
—
—
0
0
182
1799
1.05
0.08
12.0
11.9
13.76
13.76
%
0.00
177
1766
56
540
1.05
0.08
1.6
1.6
103.02
94.37
pmol/l
0.50
35
272
47
451
1.05
0.08
1.6
1.4
—
—
—
0
0
19
205
0.92
0.08
4.9
4.2
0.84
0.82
mmol/l
0.41
19
193
162
1603
1.03
0.05
3.2
2.9
1.23
1.18
mmol/l
0.41
155
1509
50
487
1.03
0.04
2.5
2.0
—
—
—
0
0
15
141
1.07
0.03
7.3
7.9
106.13
105.01
mmol/l
0.87
15
141
169
1678
1.02
0.03
3.3
3.1
1.45
1.46
mmol/l
0.10
160
1584
170
1691
1.02
0.02
3.5
3.1
4.68
4.62
mmol/l
0.41
162
1595
10
102
0.98
0.00
2.5
4.6
52.70
66.24
ng/l
—
10
93
21
212
0.99
0.00
1.1
1.3
—
—
—
0
0
109
1094
0.99
0.00
9.3
8.0
4.20
3.97
e9/l
0.53
104
967
18
177
1.02
0.00
1.2
2.0
440.83
409.59
nmol/l
0.22
18
160
13
135
0.96
0.00
2.2
6.2
0.76
1.43
mmol/l
0.59
13
103
5
55
0.91
0.00
1.6
1.9
614.80
190.17
ug/l
—
5
49
9
99
0.91
-0.00
5.4
7.4
24.86
24.81
mmol/l
—
9
99
0
7
0.00
-0.00
0.0
3.0
—
47.43
—
0
7
0
9
0.00
-0.00
0.0
1.6
—
22.22
—
0
9
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
8
85
0.94
-0.00
1.3
1.3
4.75
3.48
ug/l
—
8
78
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
27.01
—
0
8
5
59
0.84
-0.00
2.6
2.7
86.40
103.35
ng/l
—
5
52
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
59
0.84
-0.00
1.6
1.4
—
—
—
0
0
7
70
1.00
-0.00
1.6
3.9
94.57
94.20
%
—
7
70
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
114.57
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
224.27
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
57
0.87
-0.00
1.8
1.4
—
99.23
—
0
13
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
18
180
1.00
-0.00
1.1
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
79
0.88
-0.00
1.3
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: M13_OSTEOCHONDROSIS_OF_ANKLE_JUVENILE – Osteochondrosis of ankle, juvenile
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).