Juvenile osteochondrosis

M13_JUVOSTEOCHONRHIP

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M91, M92
  • Hospital discharge: ICD-9 7321X|732[3-6]
  • Hospital discharge: ICD-8 72209|7222[8-9]
  • Cause of death: ICD-10 M91, M92
  • Cause of death: ICD-9 7321X|732[3-6]
  • Cause of death: ICD-8 72209|7222[8-9]

2 out of 7 registries used, show all original rules.

1360

4. Check minimum number of events

None

1360

5. Include endpoints

None

1360

6. Filter based on genotype QC (FinnGen only)

1318

Control definitions (FinnGen only)

Control exclude
M13_OTHERBONE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17161 7115 10008
Only index persons 15939 6633 9306
Unadjusted period prevalence (%)
Whole population 0.25 0.20 0.28
Only index persons 0.31 0.24 0.36
Median age at first event (years)
Whole population 14.72 14.39 14.83
Only index persons 14.83 14.62 14.98

-FinnGen-

Key figures

All Female Male
Number of individuals 1318 749 569
Unadjusted period prevalence (%) 0.26 0.27 0.26
Median age at first event (years) 19.58 18.56 20.92

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1360
Matched controls
13600
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M92.5
ICD-10 Finland
Juvenile osteochondrosis of tibia and fibula
363.2
307.7
309
11
M92.6
ICD-10 Finland
Juvenile osteochondrosis of tarsus
2448.0
233.1
219
*
M92.7
ICD-10 Finland
Juvenile osteochondrosis of metatarsus
1613.8
149.9
143
*
M91.1
ICD-10 Finland
Juvenile osteochondrosis of head of femur [Legg-Calvé-Perthes]
1337.9
127.2
122
*
9102
FHL
Trepanation or removal of the local bone process
44.0
112.1
67
16
72209
ICD-8 Finland
Osteochondrosis, spinalis juvenilis (Scheuermann) NUD
+∞
112.1
106
*
7324B
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of lower extremity, excluding foot[OSTEOCHONDROSIS JUVENILIS TUBEROSITATIS TIBIAE]
+∞
107.8
102
*
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
12.3
76.2
77
66
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
17.1
70.6
59
36
M92.4
ICD-10 Finland
Juvenile osteochondrosis of patella
658.2
64.4
63
*
M93.2
ICD-10 Finland
Osteochondritis dissecans
549.0
53.9
53
*
M16.7
ICD-10 Finland
Other secondary coxarthrosis
18.8
52.7
42
23
NGK05
NOMESCO Finland
Partial or total excision of bone of lower leg
88.3
46.2
51
6
M91.2
ICD-10 Finland
Coxa plana
+∞
42.9
41
*
M25.5
ICD-10 Finland
Pain in joint
2.2
40.6
497
2804
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
8.1
39.8
54
69
M79.6
ICD-10 Finland
Pain in limb
2.0
34.0
577
3627
M92.3
ICD-10 Finland
Other juvenile osteochondrosis of upper limb
+∞
32.4
31
*
NF1AA
NOMESCO Finland
Hip X-ray examination
3.5
29.9
106
317
M92.9
ICD-10 Finland
Juvenile osteochondrosis, unspecified
+∞
29.3
28
*
7325X
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of foot
+∞
29.3
28
*
N02AX02
ATC
tramadol; systemic, rectal
2.0
29.2
506
3163
NGK99
NOMESCO Finland
Other operation on bone of knee or lower leg
43.5
27.8
34
8
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.6
27.6
93
269
7323B
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of upper extremity[OSTEOCHONDROSIS JUVENILIS OSSIS LUNATUM CARPI]
+∞
27.2
26
*
7324X
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of lower extremity, excluding foot[OSTEOCHONDROSIS JUVENILIS EXTREMITATIS INFER ALIA]
+∞
26.1
25
*
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
8.6
25.8
33
39
7321A
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of hip and pelvis[COXA PLANA (LEGG-CALVô-PERTHES)]
265.5
25.8
26
*
M91.9
ICD-10 Finland
Juvenile osteochondrosis of hip and pelvis, unspecified
+∞
25.1
24
*
M22.4
ICD-10 Finland
Chondromalacia patellae
4.2
24.0
66
165
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
23.7
545
3671
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
9.5
23.6
28
30
M16.3
ICD-10 Finland
Other dysplastic coxarthrosis
19.9
23.5
35
18
ZXA05
NOMESCO Finland
Left side
2.1
23.5
271
1452
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.7
23.0
136
545
M92.0
ICD-10 Finland
Juvenile osteochondrosis of humerus
+∞
23.0
22
*
M92.8
ICD-10 Finland
Other specified juvenile osteochondrosis
233.8
22.7
23
*
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
3.4
22.0
82
253
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
3.1
21.1
94
323
M91.0
ICD-10 Finland
Juvenile osteochondrosis of pelvis
+∞
20.9
20
*
NHF25
NOMESCO Finland
Operation for debridement of ankle joint, arthroscopic
7.0
20.4
31
45
N02BE01
ATC
paracetamol; systemic, rectal
2.0
20.2
1141
9793
M54.5
ICD-10 Finland
Low back pain
1.7
20.0
483
3259
M92.2
ICD-10 Finland
Juvenile osteochondrosis of hand
+∞
19.8
19
*
M01AH05
ATC
etoricoxib; oral
1.7
19.4
755
5782
B01AB05
ATC
enoxaparin; parenteral
1.9
19.3
322
1944
NF1DA
NOMESCO Finland
X-ray of hips
5.5
18.6
36
67
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
18.4
547
3884
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.6
18.4
109
437
Z3226
NOMESCO Finland
Physiotherapist
2.0
18.2
233
1286
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.3
18.0
141
643
L13
ICPC
Hip symptom/complaint
2.1
18.0
192
992
M77.4
ICD-10 Finland
Metatarsalgia
2.7
17.9
99
383
ZXA00
NOMESCO Finland
Right side
1.9
17.8
270
1576
M92.1
ICD-10 Finland
Juvenile osteochondrosis of radius and ulna
+∞
17.7
17
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
17.5
511
3602
N03AX16
ATC
[U] pregabalin
1.9
17.4
251
1441
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
3.0
17.0
79
278
72228
ICD-8 Finland
Osteochondrosis, Juvenilis, alia definita
+∞
16.7
16
*
M01AB05
ATC
diclofenac; systemic, rectal
1.6
16.5
776
6125
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
16.2
114
496
WX320
NOMESCO Finland
Spinalanesthesy
1.8
16.1
259
1538
M03BX02
ATC
tizanidine; oral
1.6
16.0
756
5957
M19.2
ICD-10 Finland
Other secondary arthrosis
6.4
15.9
26
41
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.4
15.6
109
472
R4110
NOMESCO Finland
Physiotherapy
1.7
15.5
316
2009
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.8
15.0
257
1551
NGK00
NOMESCO Finland
Partial or total excision of bone of patella
57.3
14.8
17
*
NEK20
NOMESCO Finland
Fenestration or forage of bone of pelvis
81.0
14.6
16
*
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.2
14.5
133
646
9165
FHL
Removal of osteosynthesis material
4.7
14.5
33
71
1220
FHL
Arthroscopy
3.4
14.5
53
162
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
5.6
14.3
27
49
M23.8
ICD-10 Finland
Other internal derangements of knee
3.0
14.3
62
210
NFK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of femur
27.5
14.3
19
7
M02AA07
ATC
piroxicam; topical
1.7
14.3
330
2167
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
14.2
361
2429
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.7
13.9
74
281
M01AE02
ATC
naproxen; oral, rectal
1.5
13.7
781
6329
72211
ICD-8 Finland
Osteochondrosis, Coxae planae
+∞
13.6
13
*
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
4.5
13.3
32
72
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
13.2
159
855
A02BC02
ATC
pantoprazole; systemic
1.5
13.2
737
5924
N03AX12
ATC
[U] gabapentin; oral
1.9
13.0
174
970
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
6.2
13.0
22
36
S18
ICPC
Laceration/cut
1.5
12.9
508
3779
SPAT1153
SPAT
Removal of sutures
1.6
12.8
320
2138
N06AX21
ATC
duloxetine; oral
2.0
12.5
150
805
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
12.4
77
316
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
3.6
12.2
40
114
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
18.2
12.1
18
10
M01AC06
ATC
meloxicam; systemic, rectal
1.6
11.9
351
2434
J01FF01
ATC
clindamycin; systemic
1.6
11.9
303
2028
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
3.3
11.8
44
136
J01DB01
ATC
cefalexin; oral
1.6
11.4
1085
9637
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
3.0
11.3
49
166
M01AH01
ATC
celecoxib; oral
1.9
11.2
159
901
N02AA05
ATC
oxycodone; systemic
1.9
11.0
136
738
L15
ICPC
Knee symptom/complaint
1.6
10.9
280
1876
L17
ICPC
Foot/toe symptom/complaint
1.6
10.8
349
2465
NGF40
NOMESCO Finland
Repair of defect of cartilage in the knee joint with transplant
28.3
10.7
14
5
M89.0
ICD-10 Finland
Algoneurodystrophy
21.6
10.7
15
7
H02AB06
ATC
prednisolone; systemic
1.5
10.7
515
3959
M03BC01
ATC
orphenadrine (citrate); systemic
1.6
10.6
276
1851
NFK20
NOMESCO Finland
Epiphysiodesis of femur
60.5
10.6
12
*
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
4.0
10.5
29
73
M01AX17
ATC
nimesulide; oral
1.7
10.5
192
1176
M93.1
ICD-10 Finland
Kienböck disease of adults
110.9
10.4
11
*
7324A
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of lower extremity, excluding foot[TIBIA VARA (BLOUNT)]
+∞
10.4
10
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
10.3
403
2961
R51.80
ICD-10 Finland
Headache
1.7
10.3
232
1500
ZXD20
NOMESCO Finland
Day surgery
1.8
10.3
152
872
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
4.4
10.3
25
57
A03FA02
ATC
cisapride; oral, rectal
2.3
10.3
76
338
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
10.2
295
2027
A02BC01
ATC
omeprazole; systemic
1.6
10.2
280
1902
J01FA10
ATC
azithromycin; systemic
1.5
10.2
827
7002
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.1
10.2
94
458
X58
ICD-10 Finland
Exposure to other specified factors
1.7
10.1
212
1347
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
3.5
10.1
34
99
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.4
10.0
35
104
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.4
10.0
66
279
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
10.0
159
934
N02BF02
ATC
pregabalin; oral
2.4
10.0
71
311
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
3.5
9.8
33
96
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.0
9.7
110
579
R03AC02
ATC
salbutamol; inhalant
1.4
9.7
698
5757
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.7
9.6
198
1250
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
2.7
9.6
52
200
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
9.6
1205
11113
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
11.5
9.6
17
15
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.8
9.5
159
948
9407
FHL
Osteotomy of the upper femur
100.7
9.4
10
*
M93.9
ICD-10 Finland
Osteochondropathy, unspecified
100.7
9.4
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
9.4
368
2698
M01AH03
ATC
valdecoxib; oral
2.4
9.3
61
257
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
9.1
577
4635
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
3.6
9.0
29
82
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
8.8
244
1655
NH1AD
NOMESCO Finland
Ankle and foot CT
3.2
8.8
34
108
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
2.8
8.8
42
151
ZXE00
NOMESCO Finland
One hour or less
1.4
8.7
448
3455
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
8.7
112
616
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
3.5
8.7
29
84
L03
ICPC
Low back symptom/complaint
1.5
8.6
345
2533
M01AH02
ATC
rofecoxib; oral
2.0
8.6
97
509
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
8.5
997
8879
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
8.5
332
2426
L08
ICPC
Shoulder symptom/complaint
1.6
8.4
222
1490
J01DA01
ATC
[U] cefalexin
1.4
8.4
721
6072
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
3.2
8.4
32
101
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
2.9
8.4
38
133
7326A
ICD-9 Finland
Osteochondropathies, Other juvenile osteochondrosis
+∞
8.3
8
*
72219
ICD-8 Finland
Osteochondrosis, Coxae juvenilis NUD
+∞
8.3
8
*
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
8.3
198
1295
L86
ICPC
Back syndrome with radiating pain
2.2
8.3
67
310
J01AA02
ATC
doxycycline; systemic
1.4
8.3
823
7099
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
8.2
244
1681
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
2.3
8.2
60
267
J01DA09
ATC
[U] cefadroxil
1.5
8.2
306
2216
M54.3
ICD-10 Finland
Sciatica
2.3
8.1
63
287
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
8.1
312
2272
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
8.1
284
2030
RF210, ,
NOMESCO Finland
2.8
8.0
39
142
L16
ICPC
Ankle symptom/complaint
1.7
8.0
162
1018
9103
FHL
Partial or complete bone removal
13.1
7.9
13
10
M20.1
ICD-10 Finland
Hallux valgus (acquired)
2.1
7.8
73
358
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.7
7.8
132
789
WX702
NOMESCO Finland
Supraglottic ventilation device
2.2
7.8
67
319
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
2.8
7.7
38
139
RF410, ,
NOMESCO Finland
4.2
7.7
20
48
RF420, ,
NOMESCO Finland
4.0
7.6
21
53
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.6
7.6
24
67
M67.4
ICD-10 Finland
Ganglion
2.0
7.6
84
439
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.6
7.6
41
158
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
7.5
207
1402
72870
ICD-8 Finland
Vertebrogenic pain syndrome, Lumbalgia
7.2
7.5
17
24
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
7.5
81
420
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.3
7.4
27
83
R06AE07
ATC
cetirizine; oral
1.4
7.4
559
4578
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
7.3
202
1367
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
7.3
110
635
R06.2
ICD-10 Finland
Wheezing
2.1
7.3
65
313
M48.0
ICD-10 Finland
Spinal stenosis
1.9
7.3
86
459
72220
ICD-8 Finland
Osteochondrosis, Malacia ossia lunati (Kienböck)
+∞
7.3
7
*
7323X
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of upper extremity[OSTEOCHONDROSIS JUVENILIS EXTREMITATIS SUPER ALIA]
+∞
7.3
7
*
7327A
ICD-9 Finland
Osteochondropathies, Osteochondritis dissecans[OSTEOCHONDRITIS DISSECANS GENUS]
+∞
7.3
7
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.2
214
1473
M76.5
ICD-10 Finland
Patellar tendinitis
3.4
7.1
25
75
M01AB01
ATC
indometacin; systemic, rectal
2.3
7.1
54
244
L28
ICPC
Limited function/disability (L)
1.7
7.1
135
834
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
7.1
130
796
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
7.0
238
1684
E66.8
ICD-10 Finland
Other obesity
2.0
7.0
70
353
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.1
6.9
61
293
AA1AD
NOMESCO Finland
CT of head and brain
1.5
6.9
219
1528
NH3AA, ,
SPAT
2.0
6.8
71
363
9254
FHL
Arthrotomy (includes biopsy, revision, loose removal, fixation, and similar procedures)
8.3
6.8
14
17
R10.0
ICD-10 Finland
Acute abdomen
2.5
6.8
41
167
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
6.8
121
734
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.8
259
1876
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.3
6.8
49
217
NB1AE, ,
SPAT
2.7
6.8
35
132
Q65.80
ICD-10 Finland
Congenital dysplastic hip or acetabulum, unilateral
40.3
6.8
8
*
NGL58
NOMESCO Finland
Tenolysis or tenosynovectomy of knee or lower leg
40.3
6.8
8
*
9527
FHL
Alloarthroplasty, implant or endoprosthesis
40.3
6.8
8
*
NHF30
NOMESCO Finland
Fixation of loose fragment from ankle joint
40.3
6.8
8
*
R06.0
ICD-10 Finland
Dyspnoea
1.5
6.7
254
1835
L89
ICPC
Osteoarthrosis of hip
2.9
6.7
30
105
M67.8
ICD-10 Finland
Other specified disorders of synovium and tendon
3.7
6.6
20
54
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
6.6
216
1516
M02AA10
ATC
ketoprofen; topical
1.7
6.6
134
842
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
6.9
6.5
15
22
R42
ICD-10 Finland
Dizziness and giddiness
1.5
6.5
199
1379
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
3.2
6.5
25
80
R52.2
ICD-10 Finland
Other chronic pain
2.4
6.5
44
190
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
3.2
6.4
24
75
WX002
NOMESCO Finland
Sedation and analgesia
1.6
6.4
176
1189
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.2
6.4
52
242
NGF30
NOMESCO Finland
Fixation of loose body of joint of knee
14.4
6.4
10
7
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
6.3
955
8607
M54
ICD-10 Finland
Dorsalgia
1.6
6.3
155
1021
M91.3
ICD-10 Finland
Pseudocoxalgia
+∞
6.3
6
*
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
2.9
6.2
28
98
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
6.2
303
2294
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
2.6
6.1
35
139
NCF25
NOMESCO Finland
Operation for osteochondritis of elbow joint, arthroscopic
7.7
6.1
13
17
WX214
NOMESCO Finland
Plexus blockade at the ankle
12.6
6.1
10
8
A01
ICPC
Pain general/multiple sites
1.8
6.1
96
564
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.0
683
5882
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.0
595
5025
W19
ICD-10 Finland
Unspecified fall
1.7
6.0
111
680
E0000UV, ,
ATC
1.3
6.0
506
4175
T81.9
ICD-10 Finland
Unspecified complication of procedure
3.4
6.0
21
63
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
6.0
62
317

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
895
7535
1.55
12.70
4.4
3.7
9.69
9.39
mm/h
0.29
850
7014
691
5641
1.46
10.42
5.1
4.6
6.45
6.45
mmol/l
0.00
645
5145
869
7431
1.47
10.16
7.4
6.7
75.73
76.80
u/l
0.34
826
7022
398
2943
1.50
9.82
2.6
2.5
57.29
59.23
u/l
0.21
366
2737
410
3112
1.45
8.67
3.0
3.0
24.58
35.08
ng/l
0.79
209
1740
593
4821
1.41
8.54
2.8
2.5
—
—
—
0
0
1194
11069
1.64
8.23
14.0
10.9
20.10
21.55
mg/l
0.78
948
8449
945
8383
1.42
7.83
4.1
3.7
14.43
14.50
pmol/l
0.40
882
7704
306
2254
1.46
7.41
3.3
2.5
2650.26
4304.99
umol/l
0.43
279
2050
327
2445
1.44
7.31
2.4
2.1
408.45
246.69
u/l
0.32
312
2317
1086
9925
1.47
7.30
4.9
4.3
1.77
2.05
mu/l
1.00
1029
9288
577
4760
1.37
7.23
6.1
5.7
10.27
11.18
umol/l
1.99
547
4490
459
3661
1.38
7.04
11.9
9.5
1.11
1.16
inr
0.75
146
1187
521
4284
1.35
6.46
7.6
6.6
1.21
1.21
mmol/l
0.31
447
3671
1142
10625
1.47
6.20
14.4
11.5
139.41
139.60
mmol/l
2.21
1124
10313
1144
10658
1.46
6.06
14.6
11.6
3.95
3.93
mmol/l
1.04
1125
10320
770
6756
1.32
5.91
4.3
3.7
2268.64
1171.10
e6/l
0.21
14
78
231
1686
1.45
5.77
1.3
1.2
8.87
8.75
u/ml
0.01
87
692
50
241
2.12
5.68
3.9
9.7
1.31
1.21
mmol/l
0.49
41
204
216
1564
1.45
5.62
3.4
3.2
724.66
594.12
ng/l
0.13
137
1012
126
813
1.61
5.60
1.3
1.3
1071.60
266.48
u/ml
0.52
118
760
468
3858
1.32
5.49
6.6
6.1
1.21
1.21
mmol/l
0.72
437
3550
239
1777
1.42
5.37
1.3
1.3
29.52
25.77
iu/ml
0.16
65
552
810
7240
1.29
5.03
4.3
3.8
—
—
—
0
0
130
869
1.55
4.98
4.0
3.2
1.71
1.72
%
0.02
116
786
24
88
2.76
4.95
1.5
1.6
56.28
55.20
%
0.05
18
66
69
393
1.80
4.88
1.3
1.2
0.45
1.15
u/ml
—
6
28
31
132
2.38
4.76
1.5
1.7
—
—
—
0
0
426
3524
1.30
4.74
3.4
3.2
30.03
31.37
u/l
0.39
401
3356
293
2305
1.35
4.63
2.0
1.9
0.91
1.01
mg/l
0.44
218
1669
375
3057
1.31
4.63
2.6
2.2
—
—
—
0
0
69
405
1.74
4.43
9.4
13.0
—
—
—
0
0
38
183
2.11
4.39
1.6
1.7
17654.08
12342.56
e6/l
0.40
25
135
201
1511
1.39
4.21
1.5
1.3
432.65
504.71
titre
0.37
49
280
176
1294
1.41
4.20
2.3
2.0
—
—
—
0
0
588
5123
1.26
4.20
7.4
6.4
—
—
—
0
0
1049
9795
1.31
4.18
3.9
3.5
5.81
5.74
mmol/l
0.74
975
9089
399
3320
1.29
4.15
1.8
1.8
100.97
95.69
pmol/l
1.31
212
1844
311
2507
1.31
4.11
3.9
3.6
7.40
7.40
ph
0.41
53
496
291
2325
1.32
4.10
2.5
2.1
—
—
—
0
0
33
155
2.16
4.08
4.8
13.1
11.33
11.38
mmol/l
0.03
27
138
417
3496
1.28
4.08
3.8
3.3
59.14
85.24
e6/l
0.42
289
2341
319
2585
1.31
4.05
3.1
2.9
0.34
0.35
e6/l
0.04
243
1931
247
1932
1.34
4.02
2.7
2.4
6.00
6.92
e6/l
0.40
220
1731
33
156
2.14
4.02
4.8
13.0
104.78
105.34
mmol/l
0.32
27
139
276
2195
1.32
4.01
4.9
4.1
—
—
—
0
0
349
2868
1.29
3.98
3.0
3.0
2.35
2.36
mmol/l
0.45
319
2587
480
4105
1.26
3.96
2.4
2.3
72.72
72.47
nmol/l
0.06
449
3802
437
3698
1.27
3.93
5.4
4.9
37.38
36.92
g/l
0.97
412
3460
108
734
1.51
3.87
8.1
10.4
96.25
96.12
%
0.08
101
708
637
5636
1.24
3.87
6.9
6.0
1.98
1.98
e9/l
0.01
570
5053
367
3047
1.28
3.85
1.4
1.3
1.72
1.71
u/ml
0.01
94
809
22
89
2.50
3.81
1.1
1.0
—
—
—
0
0
1212
11602
1.41
3.80
10.1
8.6
28.31
27.68
u/l
0.39
1178
11246
156
1144
1.41
3.78
8.4
6.5
1.06
1.07
mmol/l
0.21
151
1070
50
281
1.81
3.76
3.7
8.6
0.80
0.90
%
1.32
44
261
16
55
2.93
3.74
2.5
4.4
208.18
159.12
umol/l
0.29
11
32
688
6167
1.23
3.62
9.7
8.5
4.08
3.99
e9/l
0.50
605
5395
152
1123
1.40
3.54
3.7
2.8
5.59
7.35
umol/l
1.29
131
956
600
5313
1.23
3.50
6.9
5.8
56.27
55.99
%
0.24
567
5032
610
5411
1.23
3.50
7.0
6.0
0.04
0.04
e9/l
0.39
533
4741
607
5389
1.23
3.44
7.0
6.0
29.02
29.65
%
0.79
574
5110
49
282
1.77
3.43
3.8
8.5
1.71
1.64
%
0.15
43
260
628
5598
1.23
3.41
7.5
6.3
0.20
0.19
e9/l
1.39
559
4977
312
2574
1.28
3.40
3.1
2.8
—
—
—
0
0
608
5405
1.23
3.38
7.0
6.0
0.57
0.56
e9/l
0.84
532
4736
561
4949
1.23
3.35
7.0
6.1
0.64
0.66
%
0.29
527
4660
590
5247
1.22
3.22
4.4
4.2
0.00
0.00
estimate
0.50
120
1052
294
2426
1.27
3.19
4.6
3.9
90.61
93.34
%
1.09
288
2361
581
5165
1.22
3.17
7.5
6.3
8.22
8.34
%
0.45
547
4882
594
5294
1.22
3.15
3.2
3.1
0.03
0.00
estimate
0.50
117
1008
590
5256
1.22
3.14
3.2
3.1
0.00
0.00
estimate
1.08
121
1067
337
2831
1.25
3.13
3.4
2.9
31.37
82.39
e6/l
1.19
264
2155
234
1885
1.29
3.07
1.6
1.4
19.09
20.42
nmol/l
0.92
208
1629
576
5130
1.21
3.05
7.2
6.0
2.83
2.82
%
0.03
543
4833
22
100
2.22
3.00
3.2
2.3
38.67
39.20
%
0.07
22
100
130
964
1.39
2.99
3.0
2.3
2165.81
5688.61
u/l
1.76
44
366
836
7727
1.21
2.98
3.3
3.0
45.02
40.96
u/l
0.98
793
7357
214
1711
1.30
2.97
1.6
1.6
33333753.64
32879004.74
pmol/l
0.00
177
1466
115
837
1.41
2.95
7.9
9.5
5.01
5.08
kpa
0.38
109
797
14
52
2.71
2.89
1.2
1.4
—
—
—
0
0
119
875
1.39
2.88
5.6
4.5
—
7.38
—
0
6
12
38
3.18
2.85
1.1
1.3
—
—
—
0
0
68
449
1.54
2.85
3.5
7.0
—
—
—
0
0
274
2273
1.26
2.82
4.3
4.0
10.59
9.99
mg/mmol
0.08
195
1507
155
1193
1.34
2.82
2.8
2.4
22.54
24.22
%
0.74
133
1035
114
837
1.40
2.79
7.9
9.4
12.87
13.17
kpa
0.24
108
801
81
558
1.48
2.79
2.3
2.2
5.06
8.26
ug/l
1.42
71
505
15
59
2.56
2.79
1.1
1.4
34.45
32.45
g/l
0.27
15
52
293
2453
1.25
2.79
2.3
2.1
2.63
2.74
mg/l
0.38
253
2113
10
28
3.59
2.78
3.2
1.6
—
—
—
0
0
46
278
1.68
2.76
1.5
2.0
2.89
2.35
ug/l
0.10
41
253
63
412
1.55
2.76
2.0
2.1
—
—
—
0
0
154
1190
1.33
2.74
1.7
1.6
—
—
—
0
0
946
8885
1.21
2.72
5.2
4.5
38.76
38.29
mmol/mol
0.79
898
8373
314
2660
1.23
2.68
1.6
1.4
2.04
2.19
g/l
1.04
206
1667
93
664
1.43
2.67
1.3
1.2
—
—
—
0
0
73
499
1.49
2.63
2.8
3.0
110.97
167.76
ng/l
1.33
66
437
189
1512
1.29
2.62
2.8
2.5
1.07
1.02
e6/l
0.05
115
826
52
330
1.60
2.60
1.2
1.2
—
—
—
0
0
1072
10211
1.24
2.60
4.0
3.6
4.68
4.68
mmol/l
0.04
1019
9670
109
806
1.38
2.58
3.8
4.6
1.06
0.92
%
0.11
33
265
177
1407
1.30
2.57
2.7
2.3
13.21
14.39
umol/l
1.44
162
1310
1080
10304
1.23
2.53
4.3
3.9
2.81
2.83
mmol/l
0.25
1017
9701
61
405
1.53
2.52
3.1
3.1
22.02
21.40
s
0.54
50
360
24
122
1.98
2.51
1.4
1.4
—
—
—
0
0
95
691
1.40
2.48
8.9
10.8
123.62
124.72
g/l
0.19
89
672
13
51
2.56
2.44
1.1
1.4
—
—
—
0
0
106
788
1.37
2.44
9.7
8.9
—
—
—
0
0
485
4321
1.19
2.43
2.9
2.9
6.05
5.89
ph
0.71
50
436
100
738
1.38
2.41
3.4
4.3
0.56
0.61
%
0.13
27
229
170
1357
1.29
2.40
5.7
4.0
0.82
0.82
mmol/l
0.03
164
1288
1212
11734
1.30
2.40
12.4
10.0
—
—
—
0
0
111
834
1.36
2.39
8.1
9.5
0.54
0.89
mmol/l
0.46
89
658
64
436
1.49
2.37
4.7
9.4
24.80
24.29
mmol/l
0.56
58
409
111
838
1.35
2.33
2.9
2.6
10.21
10.40
g/l
0.21
99
765
17
78
2.19
2.31
1.4
1.2
—
—
—
0
0
156
1238
1.29
2.31
1.2
1.2
—
—
—
0
0
257
2165
1.23
2.30
3.7
3.4
65.43
231.22
mg/l
1.70
179
1468
1063
10156
1.21
2.29
3.9
3.6
1.41
1.43
mmol/l
0.65
1004
9588
428
3789
1.19
2.28
2.0
1.9
—
—
—
0
0
22
113
1.96
2.26
1.1
1.1
0.48
2.17
u/ml
0.53
13
47
103
773
1.36
2.25
3.6
4.6
0.07
0.13
%
0.47
28
231
163
1306
1.28
2.25
2.8
2.3
2.37
2.41
g/l
0.28
148
1205
98
733
1.36
2.19
3.7
4.7
0.04
0.15
%
0.84
23
194
1021
9731
1.20
2.19
3.6
3.3
1.34
1.27
mmol/l
1.88
970
9160
537
4859
1.17
2.19
9.7
8.5
0.00
0.00
e9/l
0.80
440
3954
100
752
1.36
2.17
2.2
2.3
15.33
21.64
au/ml
—
9
69
97
726
1.36
2.16
1.6
1.6
354.02
301.76
mu/l
0.61
89
645
22
115
1.93
2.16
1.4
1.6
—
—
—
0
0
584
5325
1.17
2.15
3.2
2.8
100.94
93.76
ug/l
0.31
553
4995
18
88
2.06
2.12
1.1
1.0
20.52
7.61
iu/ml
—
6
23
12
49
2.46
2.10
4.4
2.6
188.57
186.43
e6/l
—
7
28
23
124
1.87
2.07
3.2
3.5
—
—
—
0
0
84
619
1.38
2.07
3.6
2.9
65.09
71.39
e9/l
0.78
67
457
48
321
1.51
1.98
1.9
2.0
1.38
1.42
g/l
0.10
40
287
162
1320
1.26
1.97
3.0
2.5
29.74
29.69
s
0.05
156
1286
220
1858
1.22
1.93
2.9
2.7
563.36
562.85
mosm/kgh2o
0.01
188
1615
136
1088
1.28
1.92
1.2
1.2
—
—
—
0
0
272
2346
1.20
1.91
3.1
3.1
—
—
—
0
0
52
357
1.47
1.90
1.3
1.2
—
—
—
0
0
700
6513
1.15
1.90
3.4
3.1
—
—
—
0
0
110
858
1.31
1.89
5.8
4.5
1.14
1.64
mmol/l
1.36
98
709
89
675
1.34
1.86
2.0
1.8
1.27
1.33
g/l
0.18
83
626
16
79
2.04
1.85
1.1
1.1
—
—
—
0
0
17
86
1.99
1.85
1.2
1.2
—
—
—
0
0
5
12
4.18
1.82
1.0
1.3
—
—
—
0
0
5
12
4.18
1.82
1.0
1.1
—
—
—
0
0
20
108
1.86
1.82
2.6
1.8
—
—
—
0
0
7
23
3.05
1.80
1.0
1.7
—
—
—
0
0
13
60
2.18
1.78
1.6
2.6
20.58
538.09
ug/l
0.68
13
54
1292
12689
1.36
1.74
20.2
15.8
40.63
41.22
%
0.83
1224
12056
174
1454
1.23
1.70
3.0
2.6
2.83
2.82
e6/l
0.00
100
771
115
917
1.28
1.69
2.5
2.4
43.76
91.06
u/l
0.42
97
778
1293
12706
1.36
1.67
19.8
15.7
30.06
30.04
pg
0.16
1283
12555
1293
12706
1.36
1.67
19.8
15.7
89.86
89.74
fl
0.46
1283
12556
1292
12695
1.35
1.67
20.0
15.8
257.32
256.21
e9/l
0.25
1269
12385
1293
12708
1.35
1.65
19.9
15.7
4.58
4.60
e12/l
0.78
1268
12379
302
2663
1.17
1.65
2.6
2.4
—
—
—
0
0
1293
12710
1.35
1.63
20.0
15.8
6.80
6.70
e9/l
1.07
1267
12377
321
2852
1.16
1.59
3.7
3.4
8.00
8.49
mmol/l
1.12
291
2484
1293
12715
1.34
1.58
20.0
15.8
137.13
137.61
g/l
0.57
1283
12559
128
1044
1.25
1.58
1.3
1.4
—
—
—
0
0
82
632
1.32
1.57
1.3
1.4
—
—
—
0
0
10
44
2.28
1.55
1.2
1.3
—
—
—
0
0
140
1156
1.24
1.55
1.5
1.4
—
—
—
0
0
54
391
1.40
1.54
2.0
2.2
—
—
—
0
0
37
249
1.50
1.53
1.0
1.1
4.93
7.11
u/ml
0.21
17
104
27
169
1.61
1.52
3.2
3.3
205.37
86.43
mg/l
0.34
21
134
27
169
1.61
1.52
3.2
3.3
31.08
30.06
mg/l
0.05
21
134
5
15
3.34
1.52
1.0
1.1
—
—
—
0
0
214
1847
1.19
1.51
3.0
3.2
1199.13
1023.13
ng/l
0.24
177
1495
6
21
2.86
1.50
1.2
1.1
—
—
—
0
0
71
540
1.33
1.50
1.1
1.1
—
—
—
0
0
412
3743
1.14
1.49
2.2
2.1
—
—
—
0
0
196
1683
1.19
1.47
2.5
2.6
91.31
113.90
ug/g
0.94
162
1353
84
657
1.30
1.46
1.1
1.2
—
—
—
0
0
31
203
1.54
1.46
1.5
1.1
—
—
—
0
0
269
2374
1.17
1.45
1.9
1.8
—
—
—
0
0
5
16
3.13
1.44
1.6
1.3
—
—
—
0
0
281
2494
1.16
1.41
1.6
1.6
1.52
1.41
mmol/l
0.92
246
2173
312
2793
1.15
1.39
3.4
3.3
0.00
0.01
estimate
1.08
116
1021
66
505
1.32
1.36
1.1
1.1
—
—
—
0
0
10
47
2.14
1.34
1.1
1.3
146.90
146.76
nmol/l
—
10
47
52
385
1.36
1.33
1.1
1.1
1.28
3.60
u/ml
1.49
28
207
38
266
1.44
1.33
1.3
1.2
1.52
11.80
u/ml
—
5
43
1054
10204
1.15
1.32
17.0
13.2
334.13
333.99
g/l
0.18
1049
10125
48
352
1.38
1.30
1.0
1.1
9.91
7.09
u/ml
0.33
22
205
8
34
2.36
1.29
1.4
1.8
—
—
—
0
0
262
2333
1.15
1.26
3.3
3.2
1.01
1.02
kg/l
0.82
30
320
87
699
1.26
1.26
1.5
1.5
15.16
19.45
iu/l
1.12
75
576
14
77
1.83
1.25
1.0
1.2
1.08
1.06
ratio
—
5
32
27
179
1.52
1.24
1.9
1.9
0.74
0.83
g/l
0.18
19
141
17
100
1.71
1.23
3.6
3.9
—
—
—
0
0
136
1150
1.20
1.23
1.7
1.5
—
—
—
0
0
161
1383
1.19
1.22
2.6
2.7
2.41
2.42
mmol/l
0.52
140
1211
10
49
2.05
1.22
1.4
1.3
—
—
—
0
0
38
272
1.41
1.20
1.1
1.1
3.88
5.26
u/ml
0.32
18
129
52
393
1.34
1.19
1.1
1.1
1.56
5.96
u/ml
—
9
63
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
37
265
1.41
1.17
1.4
1.5
0.32
0.33
nmol/l
0.08
31
222
15
87
1.73
1.15
2.1
1.9
—
—
—
0
0
5
20
2.51
1.15
10.6
15.6
—
—
—
0
0
20
126
1.60
1.14
1.4
1.2
—
24.80
—
0
8
20
126
1.60
1.14
1.0
1.1
0.82
1.72
u/ml
—
6
49
41
301
1.37
1.13
1.2
1.4
3.47
3.36
ug/l
0.08
41
281
45
336
1.35
1.13
1.0
1.1
4.11
2.31
u/ml
0.22
24
178
7
30
2.34
1.12
1.0
1.1
—
—
—
0
0
88
721
1.24
1.10
2.4
2.4
5.09
6.13
e9/l
0.30
73
624
94
776
1.23
1.10
8.8
7.5
1.28
1.37
mmol/l
0.50
94
758
7
32
2.19
1.08
1.0
1.3
2.94
1.20
u/ml
—
7
32
10
52
1.93
1.06
3.0
3.0
—
—
—
0
0
12
67
1.80
1.04
1.3
1.1
—
—
—
0
0
9
47
1.92
1.02
1.3
1.4
163.67
181.88
mmol/24h
—
9
47
64
512
1.26
1.00
1.4
1.3
—
—
—
0
0
19
123
1.55
1.00
3.4
3.1
18.28
29.85
mu/l
0.88
19
116
14
84
1.67
0.98
1.1
1.2
—
—
—
0
0
40
302
1.33
0.96
1.8
1.4
—
—
—
0
0
7
37
1.90
0.94
1.0
4.0
—
—
—
0
0
17
109
1.57
0.93
1.8
1.4
0.33
0.36
g/l
0.24
12
76
17
109
1.57
0.93
1.8
1.4
5.81
6.51
g/l
0.61
12
78
17
109
1.57
0.93
1.8
1.4
2.77
2.59
g/l
0.21
12
77
44
339
1.31
0.93
1.0
1.1
0.49
1.23
u/ml
1.01
17
157
89
746
1.21
0.93
5.3
3.9
—
—
—
0
0
32
235
1.37
0.92
2.6
2.4
—
—
—
0
0
83
692
1.21
0.91
3.0
3.4
4.76
4.71
pmol/l
0.12
71
624
213
1917
1.13
0.90
1.9
1.6
—
—
—
0
0
334
3086
1.11
0.90
2.8
2.7
—
—
—
0
0
39
297
1.32
0.90
3.1
4.6
—
—
—
0
0
17
111
1.54
0.88
1.1
1.1
0.66
6.41
u/ml
—
5
40
8
44
1.82
0.86
5.6
3.7
—
—
—
0
0
28
204
1.38
0.85
4.0
3.3
17.41
24.37
mg/l
0.98
17
125
146
1287
1.15
0.85
1.7
1.7
1283.38
1167.59
nmol/l
0.77
117
994
12
72
1.67
0.85
1.2
1.2
—
56.00
—
0
6
46
362
1.28
0.85
1.3
1.1
—
—
—
0
0
6
31
1.94
0.84
2.2
2.2
—
—
—
0
0
59
480
1.24
0.83
11.2
10.6
1.07
1.40
%
2.60
59
475
8
46
1.74
0.82
2.8
2.6
—
—
—
0
0
22
155
1.43
0.81
1.7
1.9
4.97
5.24
mmol/24h
0.18
22
137
14
90
1.56
0.78
1.9
1.8
33.64
32.83
pg
0.30
14
90
15
222
0.67
0.77
1.4
1.5
—
—
—
0
0
53
433
1.23
0.74
3.3
2.4
0.15
0.13
e6/l
0.11
53
418
75
637
1.19
0.72
1.4
1.3
246.88
242.00
miu/ml
0.04
34
307
279
2588
1.10
0.71
8.2
6.4
—
—
—
0
0
5
27
1.85
0.68
1.0
1.3
—
8.50
%
—
0
6
16
110
1.46
0.68
1.9
1.4
—
—
—
0
0
11
69
1.60
0.68
2.8
2.6
37.58
46.53
%
—
5
35
7
43
1.63
0.67
1.0
1.0
—
—
—
0
0
29
223
1.31
0.66
1.0
1.1
1.24
2.62
u/ml
1.70
19
109
5
28
1.79
0.66
1.0
1.2
—
—
—
0
0
52
431
1.21
0.65
1.7
1.7
—
—
—
0
0
7
44
1.59
0.65
1.0
1.1
—
—
—
0
0
39
314
1.25
0.64
8.4
8.7
—
—
—
0
0
8
129
0.62
0.64
1.4
1.2
—
—
—
0
0
20
146
1.38
0.64
2.7
2.4
—
—
—
0
0
18
129
1.40
0.63
1.4
1.4
—
—
—
0
0
65
553
1.18
0.63
7.0
4.8
23.82
23.88
mmol/l
0.09
65
547
74
637
1.17
0.63
2.8
4.2
4.68
14.96
ug/l
0.82
60
503
83
951
0.86
0.62
1.4
1.3
—
—
—
0
0
14
97
1.45
0.59
1.1
1.1
—
—
—
0
0
107
955
1.13
0.57
3.2
3.3
—
—
—
0
0
6
36
1.67
0.56
1.8
1.5
—
—
—
0
0
11
73
1.51
0.56
1.0
1.2
—
—
—
0
0
8
55
1.46
0.56
3.8
3.8
947.00
714.11
u/ml
—
8
55
30
239
1.26
0.55
1.0
1.0
0.72
0.41
u/ml
—
9
74
45
376
1.20
0.55
4.3
3.0
0.66
0.64
%
0.15
45
376
243
2272
1.08
0.54
3.4
3.1
—
—
—
0
0
71
619
1.16
0.53
2.4
2.3
—
—
—
0
0
18
134
1.35
0.53
1.1
1.4
—
—
—
0
0
53
453
1.18
0.51
5.4
4.3
—
—
—
0
0
6
40
1.50
0.51
1.0
1.4
—
—
—
0
0
24
188
1.28
0.51
1.8
2.4
130.88
133.40
g/l
0.14
17
145
15
109
1.38
0.51
4.3
4.0
—
—
—
0
0
15
109
1.38
0.51
1.2
1.3
—
—
—
0
0
35
288
1.22
0.50
1.9
1.4
97.83
100.68
u/ml
—
6
53
6
41
1.47
0.50
1.0
3.6
—
—
—
0
0
19
246
0.77
0.49
1.5
1.1
—
—
—
0
0
261
2457
1.08
0.49
3.6
3.9
1.57
1.95
ug/l
0.97
236
2243
107
966
1.12
0.49
1.2
1.2
217.88
144.39
iu/ml
0.77
44
377
65
568
1.15
0.49
1.3
1.6
6.02
8.25
u/l
1.73
52
454
7
45
1.56
0.49
1.0
1.0
—
—
—
0
0
29
235
1.24
0.48
2.0
1.6
—
—
—
0
0
23
181
1.28
0.48
2.3
2.4
—
—
—
0
0
77
684
1.13
0.46
4.3
3.1
—
—
—
0
0
7
50
1.40
0.45
2.6
1.7
—
—
—
0
0
440
4230
1.06
0.45
2.3
2.3
—
—
—
0
0
30
247
1.22
0.44
1.2
1.1
—
7.78
—
0
22
388
3719
1.06
0.43
1.8
1.6
—
—
—
0
0
76
679
1.13
0.43
1.3
1.3
—
—
—
0
0
5
31
1.62
0.43
2.0
1.7
—
—
—
0
0
12
87
1.38
0.42
2.2
2.8
2.54
1.90
g/24h
—
5
53
5
32
1.56
0.42
3.0
2.2
48.86
86.29
ug/l
—
5
32
23
185
1.25
0.42
1.1
1.3
2.86
5.76
u/ml
—
7
80
8
58
1.38
0.41
1.0
1.2
—
—
—
0
0
308
2937
1.06
0.41
1.9
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
3.3
—
1535.87
—
0
15
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
30
250
1.20
0.40
2.0
1.5
5.50
9.73
e6/l
0.62
24
190
30
250
1.20
0.40
2.0
1.6
943.40
899.94
e6/l
0.02
25
199
21
168
1.25
0.40
1.2
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
8
61
1.31
0.39
1.9
2.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
12
159
0.75
0.38
1.9
2.9
—
—
—
0
0
11
80
1.38
0.38
3.7
2.5
—
—
—
0
0
9
66
1.37
0.38
2.6
3.7
—
—
—
0
0
9
67
1.35
0.38
1.0
1.1
—
—
—
0
0
81
734
1.11
0.37
2.6
3.1
—
—
—
0
0
9
68
1.33
0.37
1.1
1.1
1749.44
1570.74
miu/ml
—
9
68
5
37
1.35
0.37
1.6
1.3
—
—
—
0
0
11
81
1.36
0.36
3.7
2.5
4.41
4.03
mmol/l
0.56
11
81
11
81
1.36
0.36
3.7
2.5
102.64
105.68
mmol/l
1.22
11
81
34
291
1.17
0.36
2.1
2.3
7.10
5.40
umol/l
0.27
23
225
21
171
1.23
0.35
3.3
2.4
17.00
16.68
%
—
10
86
5
78
0.64
0.35
1.2
1.6
0.99
1.00
g/l
—
5
78
14
108
1.30
0.35
1.3
1.5
1.03
1.31
promille
—
9
88
1009
9955
1.05
0.35
16.6
13.1
14.09
14.16
%
0.18
997
9783
38
330
1.16
0.34
1.4
1.2
—
—
—
0
0
16
127
1.26
0.33
1.8
1.7
—
—
—
0
0
36
312
1.16
0.33
1.2
1.3
—
—
—
0
0
10
74
1.35
0.32
1.3
1.2
—
—
—
0
0
130
1216
1.08
0.32
1.6
1.5
—
—
—
0
0
27
229
1.18
0.32
1.3
1.1
—
—
—
0
0
68
618
1.11
0.31
4.8
3.9
7.44
7.41
ph
—
8
69
209
1990
1.06
0.31
1.6
1.5
—
—
—
0
0
24
202
1.19
0.31
1.1
1.1
24.26
131.03
iu/ml
—
5
61
30
258
1.17
0.31
1.3
1.4
348.08
306.89
ug/g
0.47
13
137
7
57
1.23
0.29
1.1
1.1
—
—
—
0
0
127
1350
0.93
0.29
1.9
1.9
—
—
—
0
0
27
234
1.16
0.26
1.1
1.1
—
—
—
0
0
18
214
0.84
0.26
3.1
3.0
—
—
—
0
0
9
72
1.25
0.25
2.1
2.9
—
—
—
0
0
24
207
1.16
0.25
1.3
1.1
—
—
—
0
0
9
76
1.19
0.24
5.9
2.1
—
—
—
0
0
22
255
0.86
0.24
4.0
3.4
38.95
1207.71
u/ml
1.00
22
215
167
1596
1.05
0.23
1.3
1.3
—
—
—
0
0
14
115
1.22
0.23
1.5
1.5
—
19.17
—
0
6
13
106
1.23
0.23
1.0
1.0
—
—
—
0
0
5
39
1.28
0.23
1.6
2.1
—
—
—
0
0
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
11
90
1.22
0.19
2.4
3.2
—
—
—
0
0
22
194
1.14
0.18
5.8
3.8
—
—
—
0
0
49
454
1.08
0.18
1.4
1.6
—
—
—
0
0
101
963
1.05
0.17
2.2
2.2
13.13
12.47
nmol/l
0.32
91
880
10
82
1.22
0.17
1.4
1.3
—
—
—
0
0
21
186
1.13
0.17
3.4
3.8
—
—
—
0
0
8
72
1.11
0.16
2.6
2.3
46.63
53.20
umol/l
—
8
64
45
419
1.08
0.15
2.9
2.9
—
—
—
0
0
6
80
0.75
0.15
1.0
1.5
—
—
—
0
0
44
472
0.93
0.15
2.7
3.0
—
—
—
0
0
7
87
0.80
0.14
1.0
1.0
—
—
—
0
0
70
666
1.05
0.13
3.2
3.4
1.21
1.23
mmol/l
1.57
62
579
12
103
1.17
0.13
2.4
1.8
—
—
—
0
0
82
856
0.96
0.13
2.0
2.2
—
—
—
0
0
9
109
0.82
0.13
1.0
1.4
143.19
178.45
pmol/l
—
9
109
17
190
0.89
0.13
2.1
2.5
246.21
146.40
ug/min
—
10
117
24
219
1.10
0.12
2.5
3.7
3.88
3.96
e9/l
0.09
24
219
38
355
1.07
0.12
6.1
4.2
0.31
0.28
g/l
0.09
20
174
13
147
0.88
0.11
1.9
2.6
21.82
24.85
nmol/l
0.45
13
141
10
115
0.87
0.10
1.2
1.3
—
—
—
0
0
13
115
1.13
0.10
1.2
1.9
—
—
—
0
0
17
187
0.91
0.10
1.4
1.2
—
—
—
0
0
32
300
1.07
0.10
2.0
1.9
4.20
5.42
iu/l
0.40
14
118
5
44
1.14
0.10
3.4
1.9
15.46
16.35
umol/l
—
5
44
6
56
1.07
0.08
1.3
1.2
—
—
—
0
0
16
175
0.91
0.08
2.1
1.7
—
—
—
0
0
140
1431
0.98
0.08
2.4
2.6
0.57
0.72
ug/l
1.76
74
807
5
61
0.82
0.08
1.2
1.1
289.14
187.35
iu/ml
—
5
61
24
224
1.07
0.08
2.6
4.1
56.87
55.36
%
0.28
24
224
98
1007
0.97
0.08
1.9
2.2
—
—
—
0
0
7
68
1.03
0.08
2.1
3.0
0.96
0.91
nmol/l
—
7
49
8
78
1.03
0.07
10.6
4.3
11.06
11.65
%
—
8
78
10
112
0.89
0.07
1.2
1.1
—
—
—
0
0
7
83
0.84
0.07
3.7
2.9
38942.86
40769.94
ug/l
—
7
83
9
85
1.06
0.07
1.4
1.2
—
—
—
0
0
27
255
1.06
0.07
2.3
2.2
—
—
—
0
0
28
265
1.06
0.07
2.5
4.2
1.39
1.44
mmol/l
0.13
28
259
8
94
0.85
0.06
3.3
1.9
—
—
—
0
0
11
120
0.92
0.05
3.9
1.9
—
—
—
0
0
86
843
1.02
0.04
3.0
2.5
0.22
0.23
g/l
0.70
76
792
27
258
1.05
0.04
2.9
2.8
—
—
—
0
0
10
91
1.10
0.04
1.2
1.5
11.75
10.90
umol/l
—
10
86
106
1077
0.98
0.04
1.9
2.2
—
—
—
0
0
12
111
1.08
0.04
1.0
1.3
—
—
nmol/l
—
0
0
26
252
1.03
0.02
1.4
1.4
60.42
128.80
pmol/l
0.79
26
244
108
1089
0.99
0.01
1.8
2.2
—
—
—
0
0
35
357
0.98
0.01
1.5
1.3
452.09
224.56
u/ml
1.26
20
205
21
204
1.03
0.00
4.0
3.4
1.67
2.35
mmol/l
0.70
15
129
21
216
0.97
0.00
1.8
1.6
—
—
—
0
0
52
514
1.01
0.00
1.6
1.4
—
—
—
0
0
68
686
0.99
0.00
1.5
1.4
—
—
—
0
0
108
1086
0.99
0.00
1.8
2.2
—
—
—
0
0
18
176
1.02
0.00
1.2
1.3
—
—
—
0
0
12
122
0.98
0.00
1.2
1.3
—
0.58
—
0
5
22
222
0.99
0.00
1.5
1.1
—
—
—
0
0
75
748
1.00
0.00
2.1
1.6
—
—
—
0
0
116
1158
1.00
0.00
1.2
1.2
—
—
—
0
0
29
289
1.00
0.00
1.3
1.1
—
—
—
0
0
52
515
1.01
0.00
1.6
1.5
—
—
—
0
0
53
525
1.01
0.00
1.7
1.5
—
—
—
0
0
7
69
1.01
0.00
9.7
5.1
—
—
—
0
0
7
69
1.01
0.00
1.1
1.1
—
—
—
0
0
7
69
1.01
0.00
4.9
2.6
—
—
—
0
0
8
84
0.95
0.00
2.0
1.3
86.62
75.48
umol/l
—
8
84
10
100
1.00
-0.00
2.2
3.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
89
1.01
-0.00
1.3
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
40.43
—
0
7
29
290
1.00
-0.00
1.3
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
85
0.94
-0.00
1.4
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
2.71
—
0
7
7
75
0.93
-0.00
3.1
1.7
5.96
6.09
mmol/l
—
7
55
7
70
1.00
-0.00
2.6
2.5
117.57
143.16
nmol/l
—
7
61
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
107
1070
1.00
-0.00
1.8
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
4.36
—
0
5
0
9
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
188.57
—
0
7
7
74
0.95
-0.00
1.6
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
91
0.99
-0.00
1.6
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
1142.50
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
18.30
—
0
8
5
52
0.96
-0.00
5.8
7.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_JUVOSTEOCHONRHIP and mortality.

Females

Parameter HR [95% CI] p-value
M13_JUVOSTEOCHONRHIP 1.541 [1.25, 1.9] < 0.001
Birth year 0.991 [0.98, 1.0] 0.049

During the follow-up period (1.1.1998 — 31.12.2019), 151 out of 5170 females with M13_JUVOSTEOCHONRHIP died.

Males

Parameter HR [95% CI] p-value
M13_JUVOSTEOCHONRHIP 1.025 [0.85, 1.23] 0.794
Birth year 0.99 [0.98, 1.0] 0.047

During the follow-up period (1.1.1998 — 31.12.2019), 156 out of 6552 males with M13_JUVOSTEOCHONRHIP died.

Mortality risk

Mortality risk for people of age

years, who have M13_JUVOSTEOCHONRHIP.

N-year risk Females Males
1 0.154% 0.218%
5 0.888% 1.206%
10 2.037% 3.102%
15 3.735% 6.01%
20 6.754% 10.274%

Relationships between endpoints

Index endpoint: M13_JUVOSTEOCHONRHIP – Juvenile osteochondrosis

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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