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Wide developmental disorders

KRA_PSY_DEVWIDE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F84
  • Hospital discharge: ICD-9 299[0|8|9]
  • Cause of death: ICD-10 F84
  • Cause of death: ICD-9 299[0|8|9]

2 out of 7 registries used, show all original rules.

1270

4. Check minimum number of events

None

1270

5. Include endpoints

None

1270

6. Filter based on genotype QC (FinnGen only)

1270

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F80-F89
Name in latin
Perturbationes formationales pervasivae (in pueritia)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1270 582 688
Unadjusted period prevalence (%) 0.26 0.20 0.30
Median age at first event (years) 19.17 22.63 16.24

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1101
Matched controls
10996
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F84.5
ICD-10 Finland
Asperger syndrome
2081.1
323.0
755
11
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
936.0
299.8
281
*
F90.0
ICD-10 Finland
Disturbance of activity and attention
10.7
166.9
357
471
F84.8
ICD-10 Finland
Other pervasive developmental disorders
+∞
156.0
146
*
N05AX08
ATC
risperidone; systemic
10.8
146.8
308
382
N06BA04
ATC
methylphenidate; oral
11.1
139.7
287
339
N05AH04
ATC
quetiapine; oral
5.8
128.5
454
1190
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.5
116.1
422
1118
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
7.9
107.1
270
435
F84.0
ICD-10 Finland
Childhood autism
1107.8
105.0
101
*
N05AX12
ATC
aripiprazole; systemic
8.0
91.6
224
338
F29
ICD-10 Finland
Unspecified nonorganic psychosis
7.8
87.3
217
334
N05AH03
ATC
olanzapine; systemic
6.9
87.1
239
425
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.6
86.4
361
1052
N06AB03
ATC
fluoxetine; oral
5.3
71.3
244
561
N06AB06
ATC
sertraline; oral
4.8
68.6
261
670
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
4.1
67.0
310
961
N06AX12
ATC
bupropion; oral
5.4
64.4
213
466
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
8.0
60.5
145
205
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
7.5
58.7
147
222
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
4.9
57.9
210
505
N05BA04
ATC
oxazepam; oral
3.7
57.4
298
1003
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
6.1
57.1
167
312
N06AX16
ATC
venlafaxine; oral
4.1
55.9
249
731
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
5.5
55.8
178
370
N06AB10
ATC
escitalopram; oral
3.2
55.2
358
1424
F83
ICD-10 Finland
Mixed specific developmental disorders
8.5
55.0
126
165
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
7.3
54.2
138
213
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
4.0
52.1
241
728
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
12.8
48.5
88
74
IBZ06
NOMESCO Finland
Evaluation concerning developmental neuropsychiatry
18.2
46.0
72
42
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
5.2
44.3
146
311
N06AB04
ATC
citalopram; systemic
3.6
43.3
224
733
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
8.3
42.7
98
128
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
4.9
41.9
146
330
F93.89
ICD-10 Finland
Other childhood emotional disorders
7.3
41.8
104
154
N03AG01
ATC
valproic acid; systemic, rectal
4.7
40.8
149
354
N06AX11
ATC
mirtazapine; oral
2.8
40.0
324
1438
IGV01
NOMESCO Finland
Psychiatric network contact
9.0
40.0
87
104
P29
ICPC
Psychological sympt/compl other
3.7
39.3
190
585
N03AX09
ATC
lamotrigine; oral
4.8
38.8
138
318
F40.1
ICD-10 Finland
Social phobias
5.3
36.7
117
239
F34.1
ICD-10 Finland
Dysthymia
5.8
33.7
99
183
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
8.5
33.5
75
94
F61.0
ICD-10 Finland
Mixed personality disorders
10.2
32.9
66
68
SPAT1240
SPAT
Therapeutic discussion
2.7
32.4
252
1074
P99
ICPC
Psychological disorders other
5.6
31.5
95
181
IGY99
NOMESCO Finland
Other psychiatric treatment contact
4.5
30.5
113
270
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
7.8
30.3
71
96
N05BA01
ATC
diazepam; systemic, rectal
3.5
29.7
151
479
IEV99
NOMESCO Finland
Other psychiatric network intervention
8.9
29.5
64
76
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
4.9
29.2
100
220
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.8
28.2
204
822
IGP01
NOMESCO Finland
Psychiatric family contact
6.1
28.1
79
138
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.0
28.1
94
202
N06AX26
ATC
vortioxetine; oral
3.8
28.1
126
360
N05AB03
ATC
perphenazine; systemic, rectal
7.7
28.0
66
90
N06BA12
ATC
lisdexamfetamine; oral
12.7
27.5
49
40
XA800
NOMESCO Finland
Neuropsychological investigation
3.9
26.9
116
320
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
6.0
26.8
76
134
F41.1
ICD-10 Finland
Generalized anxiety disorder
3.5
26.7
135
425
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
7.6
26.5
63
87
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.1
26.3
109
290
P01
ICPC
Feeling anxious/nervous/tense
2.3
26.2
286
1443
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
5.3
26.1
82
164
F98.8
ICD-10 Finland
Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
11.9
26.1
48
42
SPAT1307
SPAT
Psychosocial counselling and guidance
2.6
26.0
210
903
F64.9
ICD-10 Finland
Gender identity disorder, unspecified
13.8
25.6
44
33
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
5.9
25.6
73
130
F99
ICD-10 Finland
Mental disorder, not otherwise specified
6.0
25.3
71
124
F42.2
ICD-10 Finland
Mixed obsessional thoughts and acts
8.9
25.2
54
63
F88
ICD-10 Finland
Other disorders of psychological development
12.7
24.7
44
36
IAB03
NOMESCO Finland
Neuropsychiatric consultation
43.9
24.6
30
7
N06AX21
ATC
duloxetine; oral
3.6
24.5
117
351
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
23.9
228
1069
F84.10
ICD-10 Finland
Autism in atypical age
244.8
23.7
24
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
6.5
23.0
61
99
F89
ICD-10 Finland
Unspecified disorder of psychological development
15.4
22.1
36
24
N05BA06
ATC
lorazepam; systemic, sublingual
6.4
22.0
59
97
F60.9
ICD-10 Finland
Personality disorder, unspecified
7.7
21.8
51
69
N05AH02
ATC
clozapine; systemic
5.4
21.6
66
128
IGY02
NOMESCO Finland
Psychiatric monitoring contact
3.7
21.5
99
288
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
7.5
21.4
51
71
F39
ICD-10 Finland
Unspecified mood [affective] disorder
5.7
21.4
62
113
IEP99
NOMESCO Finland
Other psychiatric family intervention
7.4
21.2
51
72
N05AE04
ATC
ziprasidone; systemic
13.1
21.2
37
29
SPAT1389
SPAT
Visit based on need for special support
2.8
21.1
146
568
N05AD01
ATC
haloperidol; systemic
7.9
21.0
48
63
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.7
20.6
93
266
F60.6
ICD-10 Finland
Anxious [avoidant] personality disorder
13.8
20.6
35
26
N05AN01
ATC
lithium; oral
5.8
20.5
59
107
SPAT1234
SPAT
Support of social functional capacity
5.2
20.2
64
130
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.8
19.9
138
536
F84.11
ICD-10 Finland
Autism with atypical symptoms
+∞
19.8
19
*
Z07
ICPC
Education problem
5.4
19.6
60
117
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
8.4
19.6
43
53
F80.2
ICD-10 Finland
Receptive language disorder
5.8
19.5
56
101
P03
ICPC
Feeling depressed
2.3
19.2
211
1047
N05AA02
ATC
levomepromazine; systemic
5.7
19.2
56
103
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
4.8
19.2
65
142
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.6
18.9
88
259
P76
ICPC
Depressive disorder
2.8
18.8
126
480
F92.8
ICD-10 Finland
Other mixed disorders of conduct and emotions
10.9
18.5
35
33
F21
ICD-10 Finland
Schizotypal disorder
10.9
18.5
35
33
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
4.1
18.4
74
192
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.0
18.3
75
198
OAB43
SPAT
NA
0.3
18.2
60
1556
F92.9
ICD-10 Finland
Mixed disorder of conduct and emotions, unspecified
8.0
18.2
41
53
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.9
17.9
115
423
F41.8
ICD-10 Finland
Other specified anxiety disorders
3.9
17.6
74
200
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.2
17.5
96
320
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.7
17.3
125
498
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
3.9
17.3
72
193
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
4.4
17.1
62
146
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.4
16.9
62
147
R5599
NOMESCO Finland
Other rehabilitation service
4.7
16.9
58
129
N06AB05
ATC
paroxetine; oral
3.9
16.7
69
183
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
16.4
102
368
IBZ08
NOMESCO Finland
Gender identity assessment
12.4
16.4
29
24
F80.9
ICD-10 Finland
Developmental disorder of speech and language, unspecified
5.5
16.3
48
90
F95.2
ICD-10 Finland
Combined vocal and multiple motor tic disorder [de la Tourette]
13.0
16.2
28
22
R62.0
ICD-10 Finland
Delayed milestone
3.8
16.2
69
189
IEP03
NOMESCO Finland
Focused parental counselling
6.1
16.1
44
75
F42.1
ICD-10 Finland
Predominantly compulsive acts [obsessional rituals]
7.6
16.0
37
50
U07.2
ICD-10 Finland
COVID-19, virus not identified
0.4
15.9
101
2036
F32.1
ICD-10 Finland
Moderate depressive episode
2.8
15.8
109
422
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.3
15.8
154
720
F33.8
ICD-10 Finland
Other recurrent depressive disorders
11.4
15.8
29
26
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
8.5
15.8
34
41
N05AF03
ATC
chlorprothixene; systemic
5.5
15.7
46
86
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.9
15.5
99
365
Z72.8
ICD-10 Finland
Other problems related to lifestyle
9.6
15.5
31
33
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.4
15.2
132
581
G47.3
ICD-10 Finland
Sleep apnoea
2.4
15.2
137
614
F42.0
ICD-10 Finland
Predominantly obsessional thoughts or ruminations
6.9
15.0
37
55
F82
ICD-10 Finland
Specific developmental disorder of motor function
4.2
14.8
56
138
N06AG02
ATC
moclobemide; oral
5.7
14.7
42
76
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
5.7
14.7
42
76
RS140
NOMESCO Finland
NA
9.3
14.7
30
33
P74
ICPC
Anxiety disorder/anxiety state
2.9
14.7
94
347
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
3.5
14.6
69
206
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
14.4
14.6
24
17
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
3.2
14.6
79
262
F32.8
ICD-10 Finland
Other depressive episodes
5.4
14.5
43
82
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.8
14.4
62
172
N03AE01
ATC
clonazepam; systemic
4.0
14.3
58
152
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
4.0
14.3
58
152
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.5
14.2
114
479
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
5.3
14.2
43
84
C07AA05
ATC
propranolol; systemic
2.0
14.1
197
1074
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
0.4
14.1
87
1776
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.4
13.7
118
518
SPAT1298
SPAT
Other function in accordance with nutritional therapy nomenclature
7.7
13.7
31
41
W78
ICPC
Pregnancy
0.4
13.6
55
1319
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
13.6
213
1212
F84.12
ICD-10 Finland
Autism both in atypical age and with atypical symptoms
+∞
13.6
13
*
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
3.8
13.4
57
156
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
4.0
13.4
53
136
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
5.8
13.4
37
65
N05CF01
ATC
zopiclone; oral
2.1
13.3
165
860
F50.8
ICD-10 Finland
Other eating disorders
9.2
13.3
27
30
P28
ICPC
Limited function/disability (P)
9.8
13.2
26
27
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
6.2
13.2
35
58
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
6.2
13.2
35
58
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
5.3
13.1
39
75
SPAT1396
SPAT
Meeting with multidisciplinary group of experts
4.4
13.0
47
111
N06BA09
ATC
atomoxetine; oral
8.2
12.8
28
35
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
5.1
12.8
40
81
F64.0
ICD-10 Finland
Transsexualism
10.6
12.8
24
23
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.9
12.6
78
283
2999A
ICD-9 Finland
Psychoses with origin specific to childhood, Unspecified[LAPSUUDEN LAAJA-AL.KEHITYSHÄIR,NUD,TÄYDEL OIREYHTYM]
+∞
12.5
12
*
F84.2
ICD-10 Finland
Rett syndrome
+∞
12.5
12
*
F60.1
ICD-10 Finland
Schizoid personality disorder
24.6
12.5
17
7
N04AA02
ATC
biperiden; systemic
6.6
12.4
31
48
N06AA04
ATC
clomipramine; systemic
8.6
12.3
26
31
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
5.8
12.3
34
60
N05AE05
ATC
lurasidone; oral
10.6
12.3
23
22
RT420
NOMESCO Finland
NA
10.6
12.3
23
22
Z63.5
ICD-10 Finland
Disruption of family by separation and divorce
9.1
12.3
25
28
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.0
12.2
71
248
ICC01
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric outpatient clinic
6.2
12.2
32
53
F60.5
ICD-10 Finland
Anankastic personality disorder
7.9
12.1
27
35
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
5.9
12.1
33
57
N06AX18
ATC
reboxetine; oral
12.5
12.1
21
17
F31
ICD-10 Finland
Bipolar affective disorder
7.1
12.1
29
42
Z29
ICPC
Social problem NOS
4.1
12.0
46
116
R1250
NOMESCO Finland
Evaluation of functional capability
5.1
11.9
37
75
F71.1
ICD-10 Finland
Moderate mental retardation, significant impairment of behaviour requiring attention or treatment
47.1
11.9
14
*
N03AX11
ATC
topiramate; oral
3.9
11.8
48
127
P06
ICPC
Sleep disturbance
2.2
11.8
120
568
F93.9
ICD-10 Finland
Childhood emotional disorder, unspecified
5.7
11.8
33
59
IBB01
NOMESCO Finland
Psychiatric functioning capacity evaluation
10.6
11.8
22
21
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.0
11.7
159
852
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
4.4
11.7
42
99
SPAT1243
SPAT
Psychiatric/psychological examination
2.6
11.7
87
351
P22
ICPC
Child behaviour symptom/complaint
3.3
11.7
58
181
F43.1
ICD-10 Finland
Post-traumatic stress disorder
3.3
11.5
58
183
P85
ICPC
Mental retardation
6.8
11.5
28
42
F84.1
ICD-10 Finland
Atypical autism
+∞
11.5
11
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
11.3
181
1033
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
5.4
11.2
33
63
F42.9
ICD-10 Finland
Obsessive-compulsive disorder, unspecified
5.7
11.1
31
56
N05BA12
ATC
alprazolam; oral
2.8
11.0
72
269
IBB02
NOMESCO Finland
Psychiatric evaluation of working capacity and rehabilitation
6.7
11.0
27
41
AA400
NOMESCO Finland
Electroconvulsive therapy
6.7
11.0
27
41
Z03
ICPC
Housing/neighbourhood problem
12.0
10.8
19
16
N03AF02
ATC
oxcarbazepine; oral
3.1
10.8
58
192
N06AX03
ATC
mianserin; oral
4.7
10.8
36
79
R4120
NOMESCO Finland
Occupational therapy
2.7
10.8
75
292
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
0.3
10.8
33
892
P81
ICPC
Hyperkinetic disorder
5.0
10.7
33
67
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
4.1
10.7
40
99
N03AX16
ATC
pregabalin; oral
2.1
10.7
124
627
SPAT1310
SPAT
Counselling related to known health issue
1.6
10.7
362
2583
F81.9
ICD-10 Finland
Developmental disorder of scholastic skills, unspecified
5.2
10.6
32
63
SPAT1229
SPAT
Assessment of need for aid
4.1
10.6
40
100
IBA02
NOMESCO Finland
Evaluation of need for psychiatric rehabilitation
4.5
10.5
36
82
N05BE01
ATC
buspirone; oral
4.5
10.5
36
82
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.1
10.4
56
186
2998A
ICD-9 Finland
Psychoses with origin specific to childhood, Other specified early childhood psychoses[LAPSUUDEN LAAJA-ALAIN KEHITYSHÄIR,TÄYDEL OIREYHTYMÄ]
+∞
10.4
10
*
F84.4
ICD-10 Finland
Overactive disorder associated with mental retardation and stereotyped movements
+∞
10.4
10
*
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
4.9
10.4
33
69
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
7.8
10.4
23
30
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.2
10.4
53
170
R53
ICD-10 Finland
Malaise and fatigue
1.8
10.3
182
1074
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.2
10.3
112
549
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
5.0
10.2
32
66
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.5
10.2
78
321
F91.3
ICD-10 Finland
Oppositional defiant disorder
13.2
10.2
17
13
F20.8
ICD-10 Finland
Other schizophrenia
14.7
10.0
16
11
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
10.0
78
327
N06AB08
ATC
fluvoxamine; oral
7.1
9.8
23
33
P23
ICPC
Adolescent behaviour sympt/compl
4.6
9.8
33
74
F90.1
ICD-10 Finland
Hyperkinetic conduct disorder
10.7
9.8
18
17
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
9.7
97
457
F60.8
ICD-10 Finland
Other specific personality disorders
7.4
9.7
22
30
F79.1
ICD-10 Finland
Unspecified mental retardation, significant impairment of behaviour requiring attention or treatment
13.5
9.7
16
12
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.1
9.6
105
516
XA820
NOMESCO Finland
NA
8.5
9.6
20
24
F32
ICD-10 Finland
Depressive episode
2.4
9.5
80
347
F22.0
ICD-10 Finland
Delusional disorder
7.2
9.5
22
31
IBZ02
NOMESCO Finland
Somatic assessment of psychiatric patient
7.2
9.5
22
31
183
Kela drug reimbursment
Lamotrigin and topiramate
4.5
9.5
32
72
N05CF02
ATC
zolpidem; oral
2.1
9.4
108
541
Z71.8
ICD-10 Finland
Other specified counselling
1.6
9.4
276
1887
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
0.5
9.4
76
1434
IER01
NOMESCO Finland
Psychoeducation, group
5.6
9.4
26
47
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
3.3
9.3
46
145
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
5.8
9.2
25
44
Z50.5
ICD-10 Finland
Speech therapy
2.9
9.2
54
191
F94.9
ICD-10 Finland
Childhood disorder of social functioning, unspecified
13.8
9.2
15
11
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
4.4
9.1
32
75
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
6.3
9.1
23
37
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
5.4
9.1
26
49
F33
ICD-10 Finland
Recurrent depressive disorder
3.9
9.1
36
95
K03.66
ICD-10 Finland
Tooth plaque
2.0
9.1
122
653
F81.0
ICD-10 Finland
Specific reading disorder
4.6
9.0
30
67
R1260
NOMESCO Finland
Evaluation of communicative skills
5.1
9.0
27
54
H03AA01
ATC
levothyroxine sodium; systemic
1.9
9.0
131
724
N06AX22
ATC
agomelatine; oral
3.3
8.9
43
133
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
24.2
8.9
12
5
F32.01
ICD-10 Finland
Mild depressive episode with somatic syndrome
6.9
8.8
21
31
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
5.2
8.8
26
51
P98
ICPC
Psychosis NOS/other
5.7
8.8
24
43
F80.8
ICD-10 Finland
Other developmental disorders of speech and language
5.1
8.7
26
52
N05BA09
ATC
clobazam; oral
4.4
8.6
30
70
IEY01
NOMESCO Finland
Psychoeducation, individual
4.5
8.6
29
66
R5140
NOMESCO Finland
Monitoring the use of the aid
2.6
8.5
61
242
N05CD07
ATC
temazepam; oral
3.5
8.5
38
111
F80.1
ICD-10 Finland
Expressive language disorder
3.0
8.5
46
155
N06BA02
ATC
dexamfetamine; oral
27.7
8.5
11
*
F98.9
ICD-10 Finland
Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
5.4
8.5
24
45
IEZ99
NOMESCO Finland
Other psychiatric rehabilitation intervention
7.4
8.5
19
26
F50.0
ICD-10 Finland
Anorexia nervosa
4.1
8.4
31
77
3138X
ICD-9 Finland
Disturbance of emotions specific to childhood and adolescence, Other or mixed emotional disturbances of childhood or adolescence[MUU MÄÄRITTELTY EMOTIONAALISENA OIREENA ILM. HÄIRIÖ]
+∞
8.3
8
*
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
10.8
8.3
15
14
188
Kela drug reimbursment
Psychosis requiring demanding treatment
9.5
8.3
16
17
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.6
8.3
60
242
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
8.2
664
7592
T82
ICPC
Obesity
3.1
8.2
44
148
SPAT1284
SPAT
Extensive health certificate
2.8
8.2
52
194
SPAT1197
SPAT
Extensive health check-up of expecting family
0.5
8.2
58
1144
F44.88
ICD-10 Finland
Other definite dissociation disorder
33.6
8.1
10
*
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
3.8
8.1
32
85
P72
ICPC
Schizophrenia
3.8
8.1
32
85
F41.3
ICD-10 Finland
Other mixed anxiety disorders
3.3
8.0
39
122
3153A
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[KIELENKEHITYKSEN ERITYISVAIKEUS]
9.0
8.0
16
18
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
10.1
8.0
15
15
IER05
NOMESCO Finland
Rehabilitative psychiatric group intervention, social skills
10.1
8.0
15
15
SPAT1262
SPAT
Handing over of treatment supplies
2.0
7.9
97
500
RT490
NOMESCO Finland
NA
8.5
7.8
16
19
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
10.9
7.8
14
13
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
3.3
7.7
37
115
RT150
NOMESCO Finland
NA
4.4
7.7
26
60
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
4.2
7.6
27
65
P27
ICPC
Fear of mental disorder
3.5
7.6
33
95
N06AX17
ATC
milnacipran; oral
8.1
7.6
16
20
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.1
7.5
39
129
T07
ICPC
Weight gain
4.0
7.5
28
71
MA3AE
NOMESCO Finland
Combined first trimester screening
0.2
7.4
9
387
F92.0
ICD-10 Finland
Depressive conduct disorder
4.6
7.4
24
53
A06AD11
ATC
lactulose; oral
2.2
7.4
71
329
N05AL01
ATC
sulpiride; systemic
7.7
7.4
16
21
F84.3
ICD-10 Finland
Other childhood disintegrative disorder
+∞
7.3
7
*
F84
ICD-10 Finland
Pervasive developmental disorders
+∞
7.3
7
*
SPAT1379
SPAT
Health check-up of pregnant person
0.5
7.3
53
1038
R4170
NOMESCO Finland
Therapy forms involving educational rehabilitation
15.8
7.2
11
7
N05AE03
ATC
sertindole; oral
7.4
7.2
16
22
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.3
7.1
62
278
Z08
ICPC
Social welfare problem
4.7
7.0
22
47
N06AX05
ATC
trazodone; oral
3.6
7.0
29
81
Z00.0
ICD-10 Finland
General medical examination
1.6
7.0
197
1323
R4130
NOMESCO Finland
Speech therapy
3.1
6.9
35
115
F93.1
ICD-10 Finland
Phobic anxiety disorder of childhood
6.7
6.8
16
24
RT190
NOMESCO Finland
NA
11.0
6.8
12
11
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
6.8
828
7435
F23.3
ICD-10 Finland
Other acute predominantly delusional psychotic disorders
9.4
6.8
13
14
IBC98
NOMESCO Finland
Other child protection assessment
9.4
6.8
13
14
K59.09
ICD-10 Finland
Constipation, unspecified
2.4
6.8
54
231
R4140
NOMESCO Finland
Psychotherapy
4.3
6.7
23
54
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
0.5
6.7
55
1039
F41.09
ICD-10 Finland
UNS Panic Syndrome
2.5
6.7
51
213
Z00.8
ICD-10 Finland
Other general examinations
2.0
6.7
86
454
OAA11
SPAT
NA
0.1
6.7
*
220
Z61.8
ICD-10 Finland
Other negative life events in childhood
6.5
6.6
16
25
ICC03
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric ward
5.2
6.6
19
37
F80.0
ICD-10 Finland
Specific speech articulation disorder
4.6
6.6
21
46
F45.0
ICD-10 Finland
Somatization disorder
12.3
6.6
11
9
F40.00
ICD-10 Finland
Agoraphobia without concomitant panic disorder
8.7
6.6
13
15
F50.9
ICD-10 Finland
Eating disorder, unspecified
2.9
6.6
38
135
X78
ICD-10 Finland
Intentional self-harm by sharp object
4.4
6.5
22
51
A13
ICPC
Concern/fear medical treatment
6.9
6.5
15
22
N06AA12
ATC
doxepin; systemic
3.7
6.5
26
71
N05AF05
ATC
zuclopenthixol; systemic
7.4
6.4
14
19
A28
ICPC
Limited function/disability NOS
2.2
6.4
63
299
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
3.7
6.4
26
72
F51.0
ICD-10 Finland
Nonorganic insomnia
1.7
6.4
120
722
T90
ICPC
Diabetes non-insulin dependent
2.1
6.4
67
327
F31.8
ICD-10 Finland
Other bipolar affective disorders
3.2
6.4
31
99
A10BA02
ATC
metformin; oral
1.9
6.4
84
449
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
6.3
169
1118
IEP02
NOMESCO Finland
Child-centred family therapy
3.5
6.3
27
78
SPAT1260
SPAT
Consultation of another employee
1.6
6.3
154
998
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
5.5
6.3
17
31
3159X
ICD-9 Finland
Specific delays in development, Unspecified delay in development
11.1
6.3
11
10
R45.1
ICD-10 Finland
Restlessness and agitation
11.1
6.3
11
10
F93.80
ICD-10 Finland
Generalized anxiety in the bardom age
9.3
6.3
12
13
F94.0
ICD-10 Finland
Elective mutism
9.3
6.3
12
13
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
6.3
112
663
F44.81
ICD-10 Finland
Side person disorder
+∞
6.3
6
*
2999B
ICD-9 Finland
Psychoses with origin specific to childhood, Unspecified[LAPSUUDEN LAAJA-ALAINEN KEHITYSHÄIRIÖ NUD,JÄLKITILA]
+∞
6.3
6
*
2990A
ICD-9 Finland
Psychoses with origin specific to childhood, Infantile autism[AUTISMUS INFANTILIS,TÄYDELLINEN OIREYHTYMÄ]
+∞
6.3
6
*
F41.00
ICD-10 Finland
Moderate panic disorder
3.2
6.2
30
95
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
0.5
6.2
49
938
AA1AD
NOMESCO Finland
CT of head and brain
1.8
6.2
105
612
M35.7
ICD-10 Finland
Hypermobility syndrome
3.7
6.2
25
69
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
4.0
6.2
23
59
W11
ICPC
Contraception oral
0.6
6.2
99
1558
SPAT1301
SPAT
No procedures
1.4
6.1
290
2181
C07AB07
ATC
bisoprolol; oral
1.6
6.1
149
967
F34.8
ICD-10 Finland
Other persistent mood [affective] disorders
12.6
6.1
10
8
F94.8
ICD-10 Finland
Other childhood disorders of social functioning
8.6
6.1
12
14
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.6
6.0
75
1261
R44.3
ICD-10 Finland
Hallucinations, unspecified
10.1
6.0
11
11
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.6
6.0
25
71
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
6.0
151
986

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
231
746
3.56
59.34
1.6
1.6
1086.5
1149.1
nmol/l
0.49
179
582
207
673
3.48
52.26
2.4
3.2
—
—
—
0
0
450
2239
2.56
52.14
1.8
1.6
95.3
98.5
pmol/l
0.84
259
1233
1001
7288
2.77
48.81
4.8
3.5
14.4
14.5
pmol/l
0.44
918
6669
430
2199
2.44
45.91
2.3
2.8
2.4
2.4
mmol/l
0.49
388
2004
65
92
7.39
43.93
2.7
3.1
—
—
—
0
0
96
203
5.03
43.14
6.2
5.4
390.2
375.8
umol/l
0.38
84
187
1085
8451
2.96
42.35
5.7
4.0
1.9
1.9
mu/l
0.21
1023
7969
562
3342
2.22
41.08
5.1
8.7
1.2
1.2
mmol/l
1.77
513
3124
250
1053
2.71
39.40
1.5
1.5
417.6
23175031.4
pmol/l
1.07
208
945
1118
8955
3.09
39.31
11.5
9.8
139.7
139.5
mmol/l
3.20
1077
8669
275
1224
2.59
38.72
1.5
1.3
18.5
19.1
nmol/l
0.32
249
1091
1117
8979
3.03
38.28
11.4
9.8
3.9
3.9
mmol/l
7.14
1074
8656
589
3642
2.15
38.22
5.8
8.3
1.2
1.2
mmol/l
0.66
502
3213
568
3468
2.15
38.03
2.7
2.8
66.1
68.5
nmol/l
1.43
527
3286
291
1379
2.44
35.55
3.0
2.4
—
—
—
0
0
970
7428
2.30
34.49
4.2
2.7
5.6
5.5
mmol/l
0.72
897
6923
818
5863
2.11
34.46
5.9
6.3
89.0
87.5
u/l
0.25
748
5531
239
1062
2.54
33.36
3.0
3.2
—
—
—
0
0
134
501
2.87
26.01
3.5
3.3
—
—
—
0
0
247
1242
2.23
25.51
2.3
2.3
—
—
—
0
0
177
778
2.48
24.86
1.9
1.7
426.2
309.1
mu/l
2.54
151
699
647
4672
1.78
22.26
3.3
2.4
—
—
—
0
0
371
2287
1.88
21.34
3.3
3.9
8.6
9.1
mmol/l
0.81
312
2055
343
2072
1.90
20.95
2.1
2.6
2.6
2.7
mg/l
0.20
287
1822
31
44
7.20
20.83
1.8
2.3
15.4
16.5
umol/l
0.15
31
44
435
2835
1.81
20.82
4.6
6.1
38.6
38.0
g/l
1.29
390
2658
297
1716
1.95
20.71
3.0
2.2
304.3
314.7
u/l
0.04
281
1652
43
1522
0.26
19.52
1.2
1.2
—
—
—
0
0
33
54
6.25
19.44
4.7
4.7
289.9
230.8
umol/l
0.30
20
25
195
992
2.14
19.19
2.2
2.4
337.8
368.7
nmol/l
1.61
188
930
309
1850
1.89
19.18
3.0
3.9
7.4
7.4
ph
0.53
56
342
259
1475
1.95
18.64
2.4
2.3
—
—
—
0
0
1137
10026
2.29
18.40
9.4
7.8
30.8
28.5
u/l
1.97
1096
9717
346
2176
1.81
18.21
2.7
2.7
54.9
55.3
u/l
0.09
310
2030
69
216
3.32
18.12
1.9
1.5
—
—
—
0
0
58
162
3.70
18.11
1.8
2.1
—
—
—
0
0
268
1575
1.89
17.44
2.4
2.2
—
—
—
0
0
268
1587
1.87
16.99
2.4
2.2
—
—
—
0
0
268
1590
1.87
16.88
2.4
2.2
—
—
—
0
0
615
4692
1.60
14.91
4.5
5.4
6.1
6.2
mmol/l
0.41
564
4257
493
3569
1.62
14.84
4.4
6.2
13.7
14.2
umol/l
0.12
450
3331
1117
9957
2.01
14.79
11.1
9.2
67.8
69.3
umol/l
1.76
1117
9951
143
2600
0.49
14.37
1.5
1.6
—
—
—
0
0
249
1564
1.74
12.62
2.5
2.1
—
—
—
0
0
475
3531
1.55
12.14
6.9
7.6
—
—
—
0
0
795
6610
1.54
12.06
4.5
3.4
36.5
36.8
mmol/mol
0.30
725
6291
764
6318
1.53
11.72
3.9
3.6
7.3
7.3
mm/h
0.01
693
5891
117
590
2.08
11.62
2.8
3.3
5.2
4.9
pmol/l
0.80
100
536
271
1782
1.66
11.49
1.6
1.7
1.5
1.4
mmol/l
0.38
245
1622
600
4733
1.51
11.41
9.0
8.9
0.0
0.0
e9/l
0.13
480
3761
20
35
5.79
11.02
2.0
2.6
—
—
—
0
0
698
5741
1.48
10.43
12.6
9.4
3.7
3.8
e9/l
0.53
610
4943
912
7924
1.54
10.39
3.6
2.9
4.6
4.6
mmol/l
0.48
853
7558
74
327
2.34
10.17
1.2
1.3
—
—
—
0
0
303
4147
0.65
9.78
2.4
2.2
—
—
—
0
0
644
5285
1.44
9.30
8.1
7.8
0.2
0.2
e9/l
1.75
555
4650
904
7920
1.49
9.18
3.8
3.0
2.9
2.8
mmol/l
0.91
841
7488
626
5121
1.44
9.13
7.4
7.3
0.0
0.0
e9/l
0.13
534
4436
625
5114
1.44
9.09
7.4
7.3
0.5
0.6
e9/l
1.23
537
4428
438
3367
1.46
8.84
1.5
1.5
1.7
2.2
u/ml
0.28
100
770
85
422
2.09
8.82
7.1
10.3
1.0
1.1
inr
1.10
17
85
162
993
1.72
8.80
2.3
2.3
10.2
13.2
nmol/l
3.32
135
882
895
7858
1.47
8.71
3.6
2.9
1.3
1.4
mmol/l
9.67
836
7472
354
2619
1.49
8.65
6.9
7.6
—
—
—
0
0
177
2673
0.61
8.61
2.1
1.8
—
—
—
0
0
863
7534
1.45
8.58
3.2
2.7
1.3
1.2
mmol/l
3.66
796
7171
646
5371
1.41
8.31
7.3
7.1
2.2
2.1
e9/l
0.51
567
4756
236
1627
1.55
7.98
2.4
2.8
590.7
585.5
mosm/kgh2o
0.10
206
1422
144
881
1.72
7.86
2.0
2.4
2.4
2.4
mmol/l
2.98
120
749
45
179
2.57
7.80
1.4
1.4
9.2
11.7
u/l
0.31
34
157
39
146
2.72
7.62
2.9
2.8
19.1
18.1
%
1.32
18
80
50
213
2.40
7.52
2.1
3.7
34.7
34.1
umol/l
0.08
42
195
595
4936
1.39
7.45
7.8
7.4
8.0
8.2
%
1.19
557
4697
575
4745
1.39
7.43
3.0
3.0
63.4
72.5
ug/l
1.12
518
4500
590
4896
1.38
7.33
7.6
7.3
2.7
3.0
%
1.87
547
4643
573
4741
1.38
7.21
7.8
7.4
0.6
0.6
%
0.03
535
4506
128
781
1.71
7.06
2.9
3.7
0.2
0.2
g/l
1.05
115
738
36
851
0.41
7.00
1.3
1.3
—
—
—
0
0
21
635
0.32
6.95
1.4
1.5
—
—
—
0
0
12
21
5.76
6.59
7.6
10.0
—
—
—
0
0
185
1261
1.55
6.52
5.2
9.3
1.2
1.2
mmol/l
1.31
173
1198
14
504
0.27
6.42
1.3
1.5
—
—
—
0
0
14
502
0.27
6.37
1.3
1.4
—
—
—
0
0
614
5210
1.35
6.27
7.7
7.1
32.7
32.4
%
0.22
574
4969
40
169
2.41
6.17
4.3
4.9
2.2
2.1
mmol/l
0.15
25
102
604
5122
1.34
6.15
7.5
7.0
53.0
53.1
%
0.12
564
4885
151
1000
1.58
6.03
5.1
7.9
5.2
5.0
kpa
1.13
143
954
173
1182
1.54
6.02
3.0
3.7
157.5
148.3
mg/l
0.02
106
861
156
1044
1.56
5.96
2.0
2.7
2.6
2.5
g/l
0.35
137
970
150
998
1.57
5.87
5.2
7.9
7.4
7.4
ph
0.36
12
59
168
1148
1.53
5.84
2.0
2.7
14.7
14.8
umol/l
0.04
155
1076
39
168
2.36
5.78
2.7
4.5
—
—
—
0
0
233
3095
0.70
5.75
1.7
1.7
—
—
—
0
0
17
515
0.32
5.69
1.4
1.5
—
—
—
0
0
280
2137
1.40
5.47
4.9
4.8
1.1
1.1
inr
0.25
119
717
322
2516
1.37
5.46
3.1
3.5
93.6
47.8
e6/l
0.26
245
1913
905
9782
0.74
5.39
16.1
12.0
334.7
335.4
g/l
1.54
898
9697
174
1219
1.49
5.37
4.0
4.6
4.7
26.5
mg/mmol
1.06
105
890
1112
10469
1.50
5.33
11.1
8.0
—
—
—
0
0
137
913
1.56
5.33
1.2
1.2
87.3
137.2
iu/ml
1.07
46
327
268
2052
1.39
5.11
3.1
3.0
1.0
1.0
kg/l
0.43
23
305
164
1147
1.49
5.11
5.7
7.5
0.8
0.8
mmol/l
0.66
156
1093
77
447
1.77
5.10
3.7
4.4
1.2
1.2
mmol/l
1.61
63
392
111
724
1.58
4.75
1.9
1.8
7.5
6.5
u/l
0.47
87
545
376
3064
1.32
4.74
1.5
1.5
1.9
1.9
g/l
0.01
183
1818
251
1933
1.37
4.59
3.1
2.3
13.8
179.3
ng/l
0.60
120
768
108
714
1.56
4.38
3.9
9.9
1.6
1.4
mmol/l
0.56
101
663
137
956
1.49
4.32
2.0
2.8
23.9
23.6
%
0.07
117
863
273
3386
0.75
4.13
1.6
1.7
—
—
—
0
0
182
1352
1.40
4.12
2.9
3.1
3.5
2.7
e6/l
0.53
99
729
287
2298
1.32
4.02
3.2
3.4
0.3
0.3
e6/l
0.15
212
1712
175
1311
1.39
3.77
1.3
1.2
—
—
—
0
0
95
638
1.53
3.62
6.0
4.9
0.0
0.1
%
1.81
26
166
30
144
2.11
3.55
3.3
5.5
—
—
—
0
0
97
660
1.51
3.49
6.0
4.8
0.5
0.7
%
0.49
27
176
47
266
1.80
3.48
1.7
1.6
0.3
0.4
nmol/l
1.20
39
219
110
772
1.46
3.41
2.0
2.4
25.4
96.7
u/l
0.59
93
648
40
217
1.87
3.39
3.3
7.9
23.3
23.3
mmol/l
0.04
33
198
1057
10035
1.32
3.32
10.7
9.6
19.3
21.1
mg/l
1.06
719
7278
91
618
1.51
3.32
6.1
5.0
0.0
0.0
%
0.74
23
146
6
7
8.60
3.26
1.3
1.4
—
—
—
0
0
172
1318
1.35
3.23
1.3
1.2
26.1
24.9
iu/ml
0.04
28
344
10
28
3.59
3.20
1.1
1.3
—
—
—
0
0
7
11
6.39
3.18
2.9
1.5
42.1
14.5
nmol/l
—
7
11
212
1682
1.31
3.13
2.4
2.9
7.1
7.3
e6/l
0.07
184
1487
25
119
2.12
3.05
1.3
1.4
1.0
1.4
promille
0.61
15
89
38
211
1.83
3.02
2.2
2.9
148.9
286.2
ug/l
1.59
33
196
364
3101
1.24
3.02
3.8
4.0
55.0
63.0
e6/l
0.09
259
2052
135
1009
1.38
2.97
2.0
4.9
6.3
6.6
umol/l
0.12
112
844
269
3221
0.79
2.94
2.2
2.0
—
—
—
0
0
321
3767
0.80
2.94
3.8
4.0
—
—
—
0
0
13
46
2.84
2.92
1.8
2.7
—
—
—
0
0
150
1144
1.35
2.91
4.0
7.9
1.2
1.3
mmol/l
0.19
120
894
77
521
1.51
2.89
1.2
1.2
—
—
—
0
0
125
928
1.38
2.87
2.3
1.6
—
—
—
0
0
69
458
1.54
2.83
3.1
2.8
—
—
—
0
0
39
224
1.76
2.80
1.7
1.7
—
—
—
0
0
203
1626
1.30
2.80
3.7
4.1
—
—
—
0
0
1198
11654
1.50
2.79
18.9
13.9
268.0
260.4
e9/l
3.93
1153
11301
94
1292
0.71
2.72
1.5
1.5
—
—
—
0
0
88
620
1.45
2.72
4.6
4.4
0.1
0.5
%
3.26
21
132
167
1311
1.31
2.67
1.3
1.4
315.0
485.6
titre
1.28
24
208
17
73
2.35
2.65
1.4
1.2
80.1
41.9
u/l
0.22
17
68
10
32
3.14
2.65
1.0
1.2
—
—
—
0
0
100
728
1.41
2.59
1.9
1.7
11.3
12.6
iu/l
0.25
78
561
1198
11672
1.47
2.56
18.8
13.8
29.4
29.6
pg
2.16
1172
11524
1198
11673
1.47
2.55
18.8
13.8
87.7
88.0
fl
1.43
1172
11524
1198
11676
1.46
2.51
18.9
13.8
4.8
4.7
e12/l
3.38
1151
11299
77
538
1.46
2.50
4.4
7.0
50.7
62.3
ng/l
2.07
68
516
279
2353
1.24
2.50
3.2
3.3
—
—
—
0
0
33
188
1.78
2.46
1.5
1.4
359.3
355.1
ug/g
0.03
15
100
268
2257
1.24
2.43
2.9
3.2
0.0
0.0
estimate
1.08
102
860
660
6054
1.19
2.41
3.8
3.7
—
—
—
0
0
1198
11685
1.45
2.40
19.1
14.0
139.3
138.6
g/l
1.02
1173
11534
1198
11686
1.45
2.39
19.0
13.8
6.7
6.8
e9/l
0.14
1152
11314
11
40
2.76
2.37
1.2
1.3
—
24.2
—
0
6
610
5564
1.19
2.36
3.9
3.6
256.4
333.4
e6/l
—
7
61
964
9158
1.22
2.35
16.2
12.4
13.2
13.2
%
0.11
939
8979
33
191
1.75
2.35
1.5
1.6
—
—
—
0
0
14
59
2.39
2.29
1.1
1.1
—
—
—
0
0
17
338
0.50
2.24
1.2
1.2
—
—
—
0
0
206
2468
0.80
2.21
2.3
2.5
—
—
—
0
0
157
1941
0.78
2.21
2.5
2.4
—
—
—
0
0
17
336
0.50
2.21
1.2
1.2
—
—
—
0
0
231
1937
1.24
2.17
2.4
2.2
—
—
—
0
0
121
939
1.32
2.13
2.5
2.6
1.1
1.2
ug/l
0.16
103
864
111
851
1.33
2.13
5.9
7.9
—
—
—
0
0
45
670
0.66
2.04
1.2
1.3
301.4
253.2
miu/ml
0.19
11
326
64
451
1.44
2.04
1.6
1.4
—
—
—
0
0
38
240
1.60
2.00
2.3
2.2
—
—
—
0
0
49
330
1.50
1.96
2.0
3.2
0.1
0.1
e6/l
0.67
49
319
82
614
1.36
1.86
1.2
1.2
—
38.8
—
0
19
107
836
1.31
1.83
1.2
1.3
—
—
—
0
0
39
581
0.66
1.80
1.1
1.2
1.0
3.7
u/ml
2.16
14
188
214
1820
1.21
1.76
2.4
3.0
164.1
115.0
ug/g
0.56
137
1461
1005
10397
0.84
1.76
14.1
10.9
40.5
40.9
%
0.97
729
9011
140
1138
1.26
1.76
2.7
3.1
142.7
1112.4
ng/l
3.48
67
604
233
2693
0.83
1.73
1.8
1.7
—
—
—
0
0
149
1225
1.24
1.70
1.3
1.2
11.9
6.3
u/ml
0.40
47
472
20
111
1.81
1.69
1.1
1.1
—
—
—
0
0
103
811
1.29
1.68
2.7
3.4
—
—
—
0
0
8
31
2.59
1.66
1.0
1.3
—
—
—
0
0
15
76
1.98
1.64
1.5
1.6
—
—
—
0
0
29
181
1.62
1.64
1.4
2.7
140.8
137.8
g/l
0.38
23
145
5
14
3.58
1.61
1.2
1.1
—
—
—
0
0
10
43
2.34
1.60
4.4
1.4
1.6
1.0
nmol/l
—
10
33
266
2329
1.18
1.60
5.7
4.6
—
—
—
0
0
8
32
2.51
1.59
1.4
1.3
128.3
139.2
nmol/l
—
8
32
15
77
1.96
1.59
1.3
1.2
—
—
—
0
0
6
20
3.01
1.58
1.2
2.1
—
—
—
0
0
34
223
1.54
1.58
1.0
1.1
—
—
—
0
0
46
322
1.44
1.57
3.2
4.0
72.9
137.5
ng/l
1.61
38
272
15
78
1.93
1.54
1.1
1.2
—
—
nmol/l
—
0
0
0
42
0.00
1.52
0.0
1.3
—
—
—
0
0
6
21
2.86
1.50
1.0
1.4
—
—
—
0
0
23
367
0.62
1.49
1.0
1.1
0.0
0.6
u/ml
—
10
135
128
1061
1.23
1.39
5.6
10.1
—
—
—
0
0
68
521
1.32
1.39
1.9
4.3
65.8
67.2
e9/l
0.12
47
348
31
455
0.67
1.38
1.2
1.2
—
—
—
0
0
62
469
1.34
1.38
1.7
1.8
33.5
36.3
nmol/l
0.47
62
463
27
175
1.55
1.35
1.7
10.0
—
—
—
0
0
32
462
0.68
1.32
2.1
2.4
—
—
—
0
0
15
83
1.82
1.31
1.1
1.1
—
—
—
0
0
14
76
1.85
1.30
1.0
1.0
—
—
—
0
0
17
281
0.60
1.30
1.2
1.2
—
—
—
0
0
73
923
0.78
1.29
1.7
1.4
—
—
—
0
0
27
401
0.67
1.29
1.6
1.8
—
—
—
0
0
99
807
1.25
1.27
6.3
8.4
9.6
9.7
kpa
0.17
94
774
22
339
0.64
1.26
1.8
1.5
1.1
1.2
g/l
0.17
22
320
33
468
0.70
1.25
1.6
1.5
—
—
—
0
0
5
119
0.42
1.24
3.0
1.4
—
—
—
0
0
114
947
1.22
1.23
3.9
7.9
23.8
23.6
mmol/l
0.24
109
912
34
238
1.44
1.21
1.1
1.1
—
—
—
0
0
0
35
0.00
1.15
0.0
8.4
—
—
—
0
0
43
318
1.36
1.14
1.7
2.0
3.7
8.3
ug/l
2.43
35
276
27
388
0.69
1.12
1.6
1.8
76.1
100.6
u/ml
—
5
52
17
104
1.64
1.09
1.6
2.5
—
—
—
0
0
7
33
2.13
1.05
4.4
3.0
—
—
—
0
0
46
352
1.32
1.00
1.5
1.7
—
—
—
0
0
38
504
0.75
1.00
1.4
1.7
277.6
201.2
u/ml
—
8
279
30
413
0.72
1.00
1.1
1.1
0.6
7.1
u/ml
7.59
17
211
19
283
0.67
0.97
1.0
1.1
—
—
—
0
0
15
92
1.64
0.97
1.1
1.2
—
—
—
0
0
19
124
1.54
0.97
1.3
1.4
—
—
—
0
0
51
646
0.78
0.96
1.1
1.2
3.4
2.0
u/ml
0.43
30
363
13
77
1.70
0.95
1.3
1.3
—
—
—
0
0
0
32
0.00
0.95
0.0
3.8
—
13.2
—
0
15
26
363
0.71
0.95
2.5
3.4
5.2
8.2
umol/l
1.68
18
290
124
1431
0.85
0.94
3.0
2.9
316.4
3302.3
umol/l
2.98
98
1315
105
895
1.19
0.92
2.3
3.1
10.2
9.9
g/l
0.35
95
835
34
253
1.35
0.90
1.8
1.8
3.1
5.5
iu/l
—
10
95
46
584
0.78
0.90
1.0
1.2
0.5
1.1
u/ml
0.89
27
356
5
103
0.48
0.89
1.0
1.3
—
—
—
0
0
6
29
2.07
0.89
1.2
1.1
—
—
—
0
0
8
42
1.91
0.88
1.6
2.2
—
—
—
0
0
48
596
0.80
0.80
1.1
1.2
3.7
7.3
u/ml
1.07
31
406
25
339
0.73
0.79
1.2
1.1
—
8.9
—
0
22
14
211
0.66
0.79
1.1
1.4
0.7
13.7
u/ml
—
9
112
84
714
1.19
0.78
1.5
1.9
1.1
1.1
g/l
0.04
73
669
95
818
1.17
0.77
2.9
5.5
1.4
1.5
%
0.55
78
760
0
28
0.00
0.76
0.0
2.3
—
—
—
0
0
29
380
0.76
0.75
1.0
1.1
4.5
8.6
u/ml
0.88
16
205
5
24
2.09
0.74
1.0
1.5
—
—
—
0
0
29
219
1.33
0.73
1.3
1.2
—
2.9
—
0
19
236
2167
1.11
0.73
3.8
5.6
92.8
91.0
%
0.59
224
2128
21
150
1.41
0.73
1.4
1.4
110.4
52.6
pmol/l
0.44
21
142
66
553
1.20
0.73
1.3
1.3
—
—
—
0
0
10
61
1.64
0.68
1.3
1.3
—
73.6
—
0
7
5
91
0.55
0.67
1.4
1.2
5.5
12.5
u/ml
—
5
82
10
62
1.62
0.65
1.4
1.4
1.8
1.1
nmol/l
—
10
52
27
207
1.31
0.64
3.3
6.4
—
—
—
0
0
5
29
1.73
0.64
2.6
3.0
—
—
—
0
0
6
101
0.59
0.62
15.0
3.8
—
—
—
0
0
18
130
1.39
0.61
1.2
1.3
24.6
58.2
pmol/l
—
10
33
14
198
0.70
0.60
2.6
2.6
—
—
—
0
0
13
185
0.70
0.58
1.1
1.3
—
—
—
0
0
6
35
1.72
0.57
1.0
1.7
—
—
—
0
0
8
54
1.48
0.57
1.0
1.7
31.4
32.3
pg
—
8
54
12
81
1.49
0.57
1.7
1.5
—
—
—
0
0
13
183
0.71
0.55
1.5
1.1
—
—
—
0
0
66
574
1.16
0.52
2.4
2.0
4.0
4.1
e9/l
0.20
48
506
12
83
1.45
0.52
1.3
1.3
1.4
1.8
mmol/l
1.99
12
78
13
180
0.72
0.51
2.5
4.5
4.1
12.7
u/ml
0.92
13
160
33
270
1.23
0.50
1.3
3.1
—
—
—
0
0
189
1755
1.09
0.50
1.9
2.9
0.7
1.3
mg/l
3.29
124
1186
12
167
0.72
0.49
2.0
3.4
—
42.4
—
0
11
10
144
0.69
0.49
1.3
1.7
—
—
—
0
0
22
172
1.28
0.48
1.1
1.7
—
—
—
0
0
27
217
1.25
0.48
7.3
7.4
—
—
—
0
0
7
47
1.49
0.47
20.0
7.4
—
—
—
0
0
63
551
1.15
0.47
5.5
10.7
0.9
0.3
mmol/l
0.49
47
439
22
173
1.28
0.46
1.2
1.3
5.8
4.1
u/ml
0.25
11
84
5
83
0.60
0.45
1.4
1.2
—
—
—
0
0
34
283
1.21
0.45
1.2
2.9
3.4
3.5
mmol/l
0.20
34
271
13
174
0.74
0.43
2.8
1.9
—
—
—
0
0
6
91
0.66
0.42
1.0
1.1
—
—
—
0
0
20
158
1.27
0.42
1.3
3.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
18
141
1.28
0.40
1.4
1.4
—
—
—
0
0
20
159
1.26
0.40
1.3
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
88
968
0.90
0.40
1.4
1.5
—
—
—
0
0
7
104
0.67
0.39
1.4
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
18
142
1.27
0.38
1.3
1.3
4.8
6.2
g/l
1.85
13
108
18
142
1.27
0.38
1.3
1.3
0.3
0.4
g/l
2.09
13
105
18
142
1.27
0.38
1.3
1.3
2.1
2.5
g/l
0.66
13
107
36
308
1.17
0.37
1.4
2.9
354.1
436.3
mg/l
0.72
36
296
5
37
1.35
0.37
1.8
1.2
—
—
—
0
0
14
180
0.78
0.37
4.1
3.0
19.9
25.1
mg/l
—
7
118
80
728
1.11
0.35
1.5
1.5
—
—
—
0
0
15
189
0.79
0.34
1.7
3.2
1.3
1.5
e9/l
—
6
117
13
166
0.78
0.33
1.8
3.3
10.6
11.2
%
—
8
139
6
90
0.66
0.32
11.7
3.8
—
—
—
0
0
34
295
1.16
0.31
7.7
13.9
—
—
—
0
0
25
211
1.19
0.31
2.9
4.2
51.6
52.9
%
0.23
25
211
11
142
0.77
0.31
1.0
1.0
—
—
—
0
0
21
250
0.84
0.30
1.0
1.1
—
—
—
0
0
15
120
1.25
0.30
2.0
2.4
—
—
—
0
0
14
111
1.26
0.30
1.0
1.1
—
—
—
0
0
67
612
1.10
0.29
1.3
1.2
—
—
—
0
0
33
288
1.15
0.29
1.3
3.0
8.0
15.2
e6/l
0.55
27
213
30
260
1.16
0.29
4.2
3.0
—
—
—
0
0
26
223
1.17
0.28
1.2
1.1
162.2
173.5
iu/ml
—
9
76
44
394
1.12
0.27
1.2
1.3
—
—
—
0
0
9
119
0.75
0.27
1.1
1.1
161.4
236.3
mg/l
—
9
103
111
1042
1.07
0.26
2.5
2.6
6825.4
5389.0
u/l
0.10
30
384
24
206
1.17
0.26
2.9
4.1
3.3
3.6
e9/l
0.51
24
206
5
74
0.67
0.26
1.4
1.2
—
—
—
0
0
20
169
1.19
0.26
1.3
4.3
—
—
—
0
0
5
75
0.67
0.26
1.0
1.1
1794.4
1611.9
miu/ml
—
5
75
28
245
1.15
0.24
3.3
6.6
—
—
—
0
0
25
217
1.15
0.24
1.2
1.6
0.4
0.7
g/l
2.15
18
172
27
236
1.15
0.24
2.2
4.5
2.7
6.3
ug/l
1.04
19
173
6
81
0.74
0.24
1.0
1.0
—
7.9
—
0
11
53
577
0.91
0.23
1.0
1.1
—
—
—
0
0
13
157
0.83
0.22
1.5
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
139.4
—
0
11
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
43.5
—
0
11
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
8
104
0.77
0.21
3.6
9.1
10.3
9.1
mg/l
—
8
95
0
13
0.00
0.21
0.0
1.9
—
332.9
—
0
8
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
9
112
0.80
0.20
1.0
1.4
—
242.5
—
0
24
9
112
0.80
0.20
1.0
1.4
—
326.0
—
0
5
124
1184
1.05
0.19
1.7
1.6
—
—
—
0
0
12
100
1.20
0.18
2.1
15.0
13.3
12.1
%
0.57
12
100
202
2085
0.96
0.18
1.7
1.7
—
—
—
0
0
7
61
1.15
0.17
1.0
1.1
200.6
229.6
iu/ml
—
7
61
84
797
1.06
0.17
1.1
1.2
—
—
—
0
0
8
72
1.11
0.16
2.4
2.1
—
—
—
0
0
248
2541
0.97
0.15
2.4
2.6
—
—
—
0
0
19
213
0.89
0.15
1.1
1.4
0.5
4.4
u/ml
2.07
11
122
7
88
0.79
0.14
1.3
1.2
—
—
—
0
0
442
4353
1.02
0.13
4.1
4.2
0.0
0.0
estimate
0.50
106
891
8
97
0.82
0.13
1.6
1.1
—
—
—
0
0
14
122
1.15
0.13
3.5
5.8
—
—
—
0
0
445
4384
1.02
0.13
3.0
3.0
0.0
0.0
estimate
0.00
100
863
210
2052
1.03
0.12
3.2
2.9
—
—
—
0
0
35
327
1.07
0.11
1.3
1.2
—
—
—
0
0
12
136
0.88
0.11
1.0
1.0
—
—
—
0
0
441
4356
1.02
0.10
3.0
3.0
0.0
0.0
estimate
0.50
96
844
26
280
0.93
0.10
1.7
1.8
—
4.7
—
0
6
11
125
0.88
0.10
2.1
4.0
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
45
1.11
0.09
1.0
1.0
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
5
46
1.09
0.09
1.0
1.0
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
6
54
1.11
0.09
1.0
1.0
176.8
161.6
g/l
—
6
54
6
57
1.05
0.08
1.8
1.7
8.2
5.8
mmol/l
—
6
47
5
62
0.81
0.08
2.2
3.9
—
—
—
0
0
5
64
0.78
0.08
1.2
2.4
20.2
395.0
ug/l
—
5
57
7
65
1.08
0.08
1.3
1.0
—
—
—
0
0
13
143
0.91
0.07
1.2
1.3
1.7
25.1
u/ml
—
8
113
17
157
1.08
0.07
2.3
1.9
—
—
—
0
0
17
157
1.08
0.07
2.3
1.9
—
—
—
0
0
17
157
1.08
0.07
2.3
1.9
—
—
—
0
0
17
157
1.08
0.07
2.3
1.9
—
—
—
0
0
8
92
0.87
0.06
1.1
1.2
—
—
—
0
0
9
102
0.88
0.06
1.1
1.2
—
—
—
0
0
100
1021
0.98
0.06
2.0
2.0
—
—
—
0
0
91
929
0.98
0.05
1.6
2.0
—
—
—
0
0
50
514
0.97
0.04
2.0
2.0
0.5
0.6
ug/l
0.48
28
220
29
282
1.03
0.02
2.8
2.2
—
—
—
0
0
13
124
1.05
0.00
1.0
1.0
—
—
—
0
0
33
325
1.02
0.00
1.9
1.7
—
—
—
0
0
92
923
1.00
0.00
1.3
1.3
188.6
328.6
u/ml
1.31
86
850
38
385
0.99
0.00
5.0
5.9
0.4
0.3
g/l
0.23
23
261
10
105
0.95
0.00
1.3
1.6
1583.2
11492.5
e6/l
—
5
76
19
188
1.01
0.00
1.2
1.1
—
—
—
0
0
39
388
1.01
0.00
1.1
1.1
—
—
—
0
0
12
115
1.04
0.00
1.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
8
80
1.00
0.00
6.5
11.2
11.6
11.5
mmol/l
—
8
67
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
4.2
—
13.4
—
0
5
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
0.00
6.5
11.1
110.0
105.0
mmol/l
—
8
68
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
6
69
0.87
0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
3.9
—
0.5
—
0
7
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
30.0
—
0
6
0
7
0.00
0.00
0.0
9.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
8.4
—
6.5
—
0
5
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
2.0
—
0
8
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
0.00
1.0
1.1
—
—
—
0
0
8
80
1.00
0.00
1.0
1.8
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: KRA_PSY_DEVWIDE – Wide developmental disorders

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).