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Autism

F5_AUTISM

autism: A disorder characterized by marked impairments in social interaction and communication accompanied by a pattern of repetitive, stereotyped behaviors and activities. Developmental delays in social interaction and language surface prior to age 3 years.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F84.0, F84.1, F84.5
  • Hospital discharge: ICD-9 2990
  • Cause of death: ICD-10 F84.0, F84.1, F84.5
  • Cause of death: ICD-9 2990

2 out of 7 registries used, show all original rules.

974

4. Check minimum number of events

None

974

5. Include endpoints

None

974

6. Filter based on genotype QC (FinnGen only)

974

Control definitions (FinnGen only)

Control exclude
F5_PSYCHDEV

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 974 459 515
Unadjusted period prevalence (%) 0.19 0.16 0.23
Median age at first event (years) 23.37 25.81 21.20

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
844
Matched controls
8441
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F84.5
ICD-10 Finland
Asperger syndrome
11967.8
323.0
750
5
F90.0
ICD-10 Finland
Disturbance of activity and attention
14.4
163.5
301
312
N05AX08
ATC
risperidone; systemic
13.3
127.5
239
243
N06BA04
ATC
methylphenidate; oral
13.5
125.6
233
231
N05AH04
ATC
quetiapine; oral
6.8
122.6
385
925
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
+∞
119.7
112
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
7.0
115.6
346
766
F84.0
ICD-10 Finland
Childhood autism
+∞
105.5
99
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
8.4
88.0
212
323
F32.9
ICD-10 Finland
Depressive episode, unspecified
5.5
86.1
309
805
N05AX12
ATC
aripiprazole; systemic
8.7
76.5
178
252
F83
ICD-10 Finland
Mixed specific developmental disorders
760.2
72.2
70
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
8.0
69.7
170
257
N05AH03
ATC
olanzapine; systemic
7.1
68.8
185
323
N06AB03
ATC
fluoxetine; oral
6.1
65.4
198
403
N06AB06
ATC
sertraline; oral
5.4
65.3
224
530
N06AX12
ATC
bupropion; oral
6.3
64.7
189
367
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
6.4
63.2
183
350
N06AB10
ATC
escitalopram; oral
3.8
58.7
318
1158
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
4.3
57.4
256
782
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
6.7
53.9
147
256
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
4.7
53.9
207
542
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
7.6
53.7
134
205
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
8.0
52.3
125
179
N06AX16
ATC
venlafaxine; oral
4.5
51.9
212
588
F84.8
ICD-10 Finland
Other pervasive developmental disorders
+∞
51.6
49
*
N05BA04
ATC
oxazepam; oral
3.8
49.7
250
835
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
16.6
48.6
79
52
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
8.3
40.9
94
125
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
5.8
38.8
117
228
F93.89
ICD-10 Finland
Other childhood emotional disorders
9.0
37.6
82
100
P29
ICPC
Psychological sympt/compl other
4.2
37.0
156
434
N06AX11
ATC
mirtazapine; oral
2.9
36.7
276
1200
F34.1
ICD-10 Finland
Dysthymia
7.7
36.7
88
125
N06AB04
ATC
citalopram; systemic
3.7
36.5
182
586
N03AX09
ATC
lamotrigine; oral
5.5
35.6
112
229
SPAT1240
SPAT
Therapeutic discussion
3.2
34.3
216
826
F40.1
ICD-10 Finland
Social phobias
5.9
34.0
100
188
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
7.4
33.8
83
122
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
9.9
33.7
69
75
F80.2
ICD-10 Finland
Receptive language disorder
339.7
33.1
33
*
N03AG01
ATC
valproic acid; systemic, rectal
5.0
32.4
110
244
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
5.3
30.9
100
210
P99
ICPC
Psychological disorders other
6.9
30.9
80
127
SPAT1307
SPAT
Psychosocial counselling and guidance
3.2
29.6
177
645
F82
ICD-10 Finland
Specific developmental disorder of motor function
107.2
28.8
31
*
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
5.2
28.8
93
195
F61.0
ICD-10 Finland
Mixed personality disorders
10.0
28.6
58
62
F41.1
ICD-10 Finland
Generalized anxiety disorder
4.1
27.9
118
325
F80.1
ICD-10 Finland
Expressive language disorder
150.0
27.8
29
*
IGV01
NOMESCO Finland
Psychiatric network contact
10.6
27.6
54
54
P01
ICPC
Feeling anxious/nervous/tense
2.6
26.6
240
1126
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
3.0
26.5
175
678
F89
ICD-10 Finland
Unspecified disorder of psychological development
268.4
25.8
26
*
F80.9
ICD-10 Finland
Developmental disorder of speech and language, unspecified
268.4
25.8
26
*
XA800
NOMESCO Finland
Neuropsychological investigation
6.6
25.7
68
111
F84.10
ICD-10 Finland
Autism in atypical age
+∞
25.1
24
*
N06BA12
ATC
lisdexamfetamine; oral
13.2
25.1
44
35
IBZ06
NOMESCO Finland
Evaluation concerning developmental neuropsychiatry
14.2
24.8
42
31
N06AX26
ATC
vortioxetine; oral
3.9
24.7
109
311
N06AX21
ATC
duloxetine; oral
4.1
24.5
100
266
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
7.2
24.3
60
89
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
5.3
24.0
76
155
F99
ICD-10 Finland
Mental disorder, not otherwise specified
7.4
24.0
58
83
SPAT1234
SPAT
Support of social functional capacity
7.3
23.4
57
83
F81.9
ICD-10 Finland
Developmental disorder of scholastic skills, unspecified
55.7
23.2
27
5
N05AB03
ATC
perphenazine; systemic, rectal
7.3
23.1
56
81
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
5.6
22.6
67
127
F64.9
ICD-10 Finland
Gender identity disorder, unspecified
12.7
22.5
40
33
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.9
22.3
75
164
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.2
22.1
87
223
Z01.8
ICD-10 Finland
Other specified special examinations
2.7
22.0
172
733
F88
ICD-10 Finland
Other disorders of psychological development
82.3
21.8
24
*
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
225.6
21.7
22
*
F98.8
ICD-10 Finland
Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
13.8
21.6
37
28
P03
ICPC
Feeling depressed
2.6
21.2
176
774
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
6.4
20.9
56
93
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
12.4
20.7
37
31
IGY99
NOMESCO Finland
Other psychiatric treatment contact
5.0
20.2
66
140
N05BA01
ATC
diazepam; systemic, rectal
3.3
19.9
108
362
F84.11
ICD-10 Finland
Autism with atypical symptoms
+∞
19.9
19
*
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
7.5
19.5
46
64
Z07
ICPC
Education problem
6.4
19.2
51
84
F42.2
ICD-10 Finland
Mixed obsessional thoughts and acts
7.9
18.8
43
57
IEV99
NOMESCO Finland
Other psychiatric network intervention
11.8
18.6
34
30
N05BA06
ATC
lorazepam; systemic, sublingual
7.2
18.1
44
64
C07AA05
ATC
propranolol; systemic
2.4
18.1
172
808
N05AE04
ATC
ziprasidone; systemic
14.1
17.9
30
22
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
4.6
17.7
62
142
F60.9
ICD-10 Finland
Personality disorder, unspecified
7.6
17.6
41
56
F21
ICD-10 Finland
Schizotypal disorder
16.0
17.6
28
18
F95.2
ICD-10 Finland
Combined vocal and multiple motor tic disorder [de la Tourette]
43.0
17.3
21
5
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.9
17.2
72
195
F60.6
ICD-10 Finland
Anxious [avoidant] personality disorder
12.4
16.9
30
25
OAB43
SPAT
NA
0.3
16.9
47
1301
N06AB05
ATC
paroxetine; oral
4.5
16.9
61
144
F32.1
ICD-10 Finland
Moderate depressive episode
3.2
16.9
95
326
IAB03
NOMESCO Finland
Neuropsychiatric consultation
64.7
16.8
19
*
SPAT1389
SPAT
Visit based on need for special support
3.1
16.7
99
351
P76
ICPC
Depressive disorder
2.9
16.5
106
397
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.8
16.4
72
204
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
11.5
16.3
30
27
N06AG02
ATC
moclobemide; oral
7.7
16.1
37
50
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
4.6
16.0
56
128
F39
ICD-10 Finland
Unspecified mood [affective] disorder
5.1
16.0
51
106
N05AN01
ATC
lithium; oral
6.1
15.9
43
73
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
+∞
15.7
15
*
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.6
15.6
127
547
F81.0
ICD-10 Finland
Specific reading disorder
38.8
15.4
19
5
IGY02
NOMESCO Finland
Psychiatric monitoring contact
4.0
15.4
62
163
F42.0
ICD-10 Finland
Predominantly obsessional thoughts or ruminations
7.7
15.3
35
47
F42.1
ICD-10 Finland
Predominantly compulsive acts [obsessional rituals]
10.0
15.3
30
31
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
5.2
15.2
47
94
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
4.2
15.2
59
150
IBZ08
NOMESCO Finland
Gender identity assessment
12.1
15.1
27
23
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.8
15.1
100
382
IEP99
NOMESCO Finland
Other psychiatric family intervention
11.1
15.1
28
26
N05AH02
ATC
clozapine; systemic
5.4
15.0
45
87
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
9.7
15.0
30
32
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.0
15.0
89
315
F20.9
ICD-10 Finland
Schizophrenia, unspecified
5.8
15.0
42
75
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.7
14.8
51
115
F33.8
ICD-10 Finland
Other recurrent depressive disorders
13.5
14.8
25
19
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
5.1
14.7
46
94
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.6
14.6
51
117
SPAT1396
SPAT
Meeting with multidisciplinary group of experts
6.6
14.6
37
58
F41.8
ICD-10 Finland
Other specified anxiety disorders
4.0
14.5
59
157
Z72.8
ICD-10 Finland
Other problems related to lifestyle
10.7
14.3
27
26
SPAT1243
SPAT
Psychiatric/psychological examination
3.3
14.3
73
234
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
22.7
14.3
20
9
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
14.2
177
937
W78
ICPC
Pregnancy
0.3
14.1
41
1120
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.7
14.0
62
177
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
8.0
13.9
31
40
F32.8
ICD-10 Finland
Other depressive episodes
6.2
13.9
37
62
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.7
13.9
97
383
F60.1
ICD-10 Finland
Schizoid personality disorder
54.3
13.8
16
*
N06AX18
ATC
reboxetine; oral
20.4
13.8
20
10
N06BA09
ATC
atomoxetine; oral
13.9
13.8
23
17
P81
ICPC
Hyperkinetic disorder
7.1
13.7
33
48
N06AX03
ATC
mianserin; oral
7.8
13.7
31
41
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
13.6
137
657
3153A
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[KIELENKEHITYKSEN ERITYISVAIKEUS]
+∞
13.6
13
*
F84.12
ICD-10 Finland
Autism both in atypical age and with atypical symptoms
+∞
13.6
13
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.0
13.6
79
278
N03AE01
ATC
clonazepam; systemic
4.5
13.4
47
109
N05AD01
ATC
haloperidol; systemic
7.4
13.3
31
43
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.5
13.3
62
185
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.1
13.3
75
257
IGP01
NOMESCO Finland
Psychiatric family contact
5.8
13.3
37
66
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
40.8
13.2
16
*
F64.0
ICD-10 Finland
Transsexualism
11.2
13.1
24
22
RT420
NOMESCO Finland
NA
28.9
13.0
17
6
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
5.5
13.0
38
72
SPAT1310
SPAT
Counselling related to known health issue
1.8
12.9
304
2023
U07.2
ICD-10 Finland
COVID-19, virus not identified
0.4
12.9
79
1607
N05AA02
ATC
levomepromazine; systemic
4.6
12.9
44
99
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.7
12.8
93
375
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
7.7
12.8
29
39
N05AF03
ATC
chlorprothixene; systemic
5.3
12.7
38
74
F92.9
ICD-10 Finland
Mixed disorder of conduct and emotions, unspecified
8.4
12.6
27
33
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
0.4
12.6
64
1393
G47.3
ICD-10 Finland
Sleep apnoea
2.4
12.5
114
519
F93.9
ICD-10 Finland
Childhood emotional disorder, unspecified
9.5
12.5
25
27
F80.8
ICD-10 Finland
Other developmental disorders of speech and language
+∞
12.5
12
*
SPAT1298
SPAT
Other function in accordance with nutritional therapy nomenclature
8.2
12.4
27
34
P74
ICPC
Anxiety disorder/anxiety state
2.9
12.3
75
271
F80.0
ICD-10 Finland
Specific speech articulation disorder
14.6
12.3
20
14
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
4.2
12.3
46
114
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.0
12.2
49
129
F31
ICD-10 Finland
Bipolar affective disorder
7.4
12.1
28
39
R5599
NOMESCO Finland
Other rehabilitation service
5.2
11.9
36
71
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
4.0
11.9
47
122
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
4.2
11.6
44
110
F60.8
ICD-10 Finland
Other specific personality disorders
13.9
11.5
19
14
F79.1
ICD-10 Finland
Unspecified mental retardation, significant impairment of behaviour requiring attention or treatment
121.6
11.5
12
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.3
11.4
109
507
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
11.4
61
203
R62.0
ICD-10 Finland
Delayed milestone
6.7
11.3
28
43
F50.8
ICD-10 Finland
Other eating disorders
9.1
11.3
23
26
IEP03
NOMESCO Finland
Focused parental counselling
9.8
11.3
22
23
AA400
NOMESCO Finland
Electroconvulsive therapy
9.8
11.3
22
23
N05BA12
ATC
alprazolam; oral
3.1
11.3
64
221
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
3.8
11.2
47
129
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
5.0
11.2
35
72
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
7.2
11.1
26
37
R1250
NOMESCO Finland
Evaluation of functional capability
6.8
11.0
27
41
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
3.9
11.0
45
121
F50.0
ICD-10 Finland
Anorexia nervosa
6.4
11.0
28
45
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
5.4
11.0
32
61
F60.5
ICD-10 Finland
Anankastic personality disorder
7.9
10.9
24
31
F41.3
ICD-10 Finland
Other mixed anxiety disorders
4.7
10.8
36
80
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
18.1
10.8
16
9
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.5
10.7
85
361
G40.9
ICD-10 Finland
Epilepsy, unspecified
4.2
10.7
40
99
N05CF01
ATC
zopiclone; oral
2.0
10.7
137
729
N05BE01
ATC
buspirone; oral
5.4
10.7
31
59
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
6.7
10.6
26
40
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
4.8
10.5
34
73
F33
ICD-10 Finland
Recurrent depressive disorder
4.8
10.5
34
73
N04AA02
ATC
biperiden; systemic
7.5
10.5
24
33
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
5.7
10.5
29
52
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
0.3
10.4
26
768
F92.8
ICD-10 Finland
Other mixed disorders of conduct and emotions
9.7
10.3
20
21
A28
ICPC
Limited function/disability NOS
3.6
10.3
45
129
N05AE05
ATC
lurasidone; oral
13.3
10.2
17
13
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.7
10.0
70
276
N05CD07
ATC
temazepam; oral
4.8
10.0
32
68
K03.66
ICD-10 Finland
Tooth plaque
2.4
9.9
84
367
F32
ICD-10 Finland
Depressive episode
2.6
9.9
70
280
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.5
9.8
44
129
N06AA04
ATC
clomipramine; systemic
9.7
9.8
19
20
F42.9
ICD-10 Finland
Obsessive-compulsive disorder, unspecified
6.6
9.8
24
37
N06AX22
ATC
agomelatine; oral
4.1
9.7
37
94
N03AF02
ATC
oxcarbazepine; oral
3.8
9.7
40
109
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
0.5
9.6
61
1239
N05CF02
ATC
zolpidem; oral
2.2
9.6
98
473
P72
ICPC
Schizophrenia
5.8
9.6
26
46
P06
ICPC
Sleep disturbance
2.2
9.6
104
515
H03AA01
ATC
levothyroxine sodium; systemic
2.1
9.5
106
532
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
4.2
9.4
35
87
F84.1
ICD-10 Finland
Atypical autism
101.1
9.4
10
*
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
8.2
9.4
20
25
P23
ICPC
Adolescent behaviour sympt/compl
5.8
9.3
25
44
SPAT1197
SPAT
Extensive health check-up of expecting family
0.4
9.2
44
988
N06AB08
ATC
fluvoxamine; oral
6.8
9.2
22
33
N03AX11
ATC
topiramate; oral
3.8
9.0
37
101
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
5.1
9.0
27
54
183
Kela drug reimbursment
Lamotrigin and topiramate
6.6
9.0
22
34
SPAT1284
SPAT
Extensive health certificate
3.3
9.0
44
139
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
3.2
8.9
46
151
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.2
8.8
92
445
RS140
NOMESCO Finland
NA
9.6
8.8
17
18
SPAT1379
SPAT
Health check-up of pregnant person
0.4
8.8
38
884
N06AX05
ATC
trazodone; oral
4.9
8.7
27
56
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.9
8.7
34
89
R4140
NOMESCO Finland
Psychotherapy
7.7
8.7
19
25
N03AX16
ATC
pregabalin; oral
2.1
8.6
100
511
P98
ICPC
Psychosis NOS/other
6.5
8.5
21
33
F50.9
ICD-10 Finland
Eating disorder, unspecified
4.0
8.5
33
86
F90.1
ICD-10 Finland
Hyperkinetic conduct disorder
20.3
8.5
12
6
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
8.4
127
718
F98.9
ICD-10 Finland
Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
8.0
8.4
18
23
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
6.3
8.3
21
34
3153X
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[PUHEEN KEHITYKSEN ERITYISVAIKEUS]
+∞
8.3
8
*
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
5.6
8.3
23
42
T82
ICPC
Obesity
3.4
8.3
38
114
N06AX17
ATC
milnacipran; oral
10.9
8.3
15
14
IBB02
NOMESCO Finland
Psychiatric evaluation of working capacity and rehabilitation
7.2
8.3
19
27
P22
ICPC
Child behaviour symptom/complaint
4.2
8.2
30
74
MA3AE
NOMESCO Finland
Combined first trimester screening
0.1
8.2
5
333
F32.01
ICD-10 Finland
Mild depressive episode with somatic syndrome
7.6
8.2
18
24
M35.7
ICD-10 Finland
Hypermobility syndrome
5.5
8.2
23
43
P27
ICPC
Fear of mental disorder
4.8
8.2
26
56
SPAT1301
SPAT
No procedures
1.6
8.1
237
1633
IBA02
NOMESCO Finland
Evaluation of need for psychiatric rehabilitation
4.9
8.1
25
52
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
3.9
8.1
32
85
R63.4
ICD-10 Finland
Abnormal weight loss
4.5
8.1
27
61
F94.9
ICD-10 Finland
Childhood disorder of social functioning, unspecified
33.7
8.1
10
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
5.1
8.1
24
48
N06BA02
ATC
dexamfetamine; oral
22.3
8.0
11
5
W11
ICPC
Contraception oral
0.5
8.0
72
1305
SPAT1229
SPAT
Assessment of need for aid
3.9
7.9
31
82
Z50.5
ICD-10 Finland
Speech therapy
5.2
7.9
23
45
R53
ICD-10 Finland
Malaise and fatigue
1.8
7.9
138
818
N05AE03
ATC
sertindole; oral
10.9
7.8
14
13
Z08
ICPC
Social welfare problem
7.0
7.8
18
26
Z29
ICPC
Social problem NOS
3.6
7.7
33
94
P28
ICPC
Limited function/disability (P)
6.5
7.7
19
30
Z50.4
ICD-10 Finland
Psychotherapy, not elsewhere classified
15.2
7.7
12
8
F34.8
ICD-10 Finland
Other persistent mood [affective] disorders
45.4
7.7
9
*
N05BA09
ATC
clobazam; oral
6.0
7.7
20
34
N17
ICPC
Vertigo/dizziness
2.3
7.7
68
306
SPAT1097
SPAT
Recording of ECG
2.6
7.7
53
209
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.9
7.7
44
155
F22.0
ICD-10 Finland
Delusional disorder
8.1
7.6
16
20
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
6.8
7.6
18
27
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
0.4
7.6
43
909
F94.0
ICD-10 Finland
Elective mutism
25.3
7.6
10
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
7.6
120
686
RT150
NOMESCO Finland
NA
9.0
7.6
15
17
Z06
ICPC
Unemployment problem
10.1
7.5
14
14
IEZ99
NOMESCO Finland
Other psychiatric rehabilitation intervention
10.1
7.5
14
14
F41.00
ICD-10 Finland
Moderate panic disorder
4.0
7.5
28
71
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
7.5
55
226
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
5.4
7.4
21
40
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
7.4
647
5706
XA820
NOMESCO Finland
NA
8.5
7.3
15
18
A06AD11
ATC
lactulose; oral
2.5
7.3
57
241
Z03
ICPC
Housing/neighbourhood problem
11.0
7.3
13
12
F93.2
ICD-10 Finland
Social anxiety disorder of childhood
+∞
7.3
7
*
3159X
ICD-9 Finland
Specific delays in development, Unspecified delay in development
+∞
7.3
7
*
F94.8
ICD-10 Finland
Other childhood disorders of social functioning
+∞
7.3
7
*
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
9.5
7.3
14
15
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
7.3
88
457
R4120
NOMESCO Finland
Occupational therapy
2.8
7.2
43
156
F45.0
ICD-10 Finland
Somatization disorder
15.9
7.2
11
7
IEP02
NOMESCO Finland
Child-centred family therapy
7.4
7.2
16
22
SPAT1216
SPAT
Assessment of functional ability
2.3
7.2
62
277
F71.1
ICD-10 Finland
Moderate mental retardation, significant impairment of behaviour requiring attention or treatment
30.3
7.2
9
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
0.4
7.2
38
823
R45.1
ICD-10 Finland
Restlessness and agitation
20.2
7.1
10
5
SPAT1139
SPAT
Nutrition survey
3.5
7.0
30
87
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
0.3
7.0
15
477
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.5
6.9
51
210
SPAT1312
SPAT
General health counselling
1.5
6.8
327
2518
OAA11
SPAT
NA
0.0
6.8
*
199
F93.1
ICD-10 Finland
Phobic anxiety disorder of childhood
11.0
6.8
12
11
F91.1
ICD-10 Finland
Unsocialized conduct disorder
40.4
6.8
8
*
T08
ICPC
Weight loss
4.3
6.8
23
54
F23.91
ICD-10 Finland
Acute and transient psychosis, unspecified without acute stress factor
16.8
6.8
10
6
R5140
NOMESCO Finland
Monitoring the use of the aid
2.5
6.7
48
195
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.5
6.7
50
206
M01AH05
ATC
etoricoxib; oral
0.6
6.7
163
2315
N06AA12
ATC
doxepin; systemic
4.5
6.7
22
50
F40.2
ICD-10 Finland
Specific (isolated) phobias
5.5
6.6
18
33
B02AA02
ATC
tranexamic acid; systemic
2.2
6.6
66
317
K59.09
ICD-10 Finland
Constipation, unspecified
3.0
6.6
35
119
F61
ICD-10 Finland
Mixed and other personality disorders
12.4
6.6
11
9
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.5
6.6
61
1101
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
6.6
546
6179
H02
ICPC
Hearing complaint
2.8
6.5
40
149
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.1
6.5
74
373
F50.1
ICD-10 Finland
Atypical anorexia nervosa
5.1
6.5
19
38
F81.1
ICD-10 Finland
Specific spelling disorder
70.4
6.4
7
*
RT490
NOMESCO Finland
NA
70.4
6.4
7
*
F25.20
ICD-10 Finland
Schizoaffective syndrome, mixed type with only concomitant bipolar and schizophrenic symptoms
14.4
6.4
10
7
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.6
6.4
169
1131
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
4.5
6.4
21
48
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.1
6.3
68
334
R42
ICD-10 Finland
Dizziness and giddiness
1.9
6.3
90
498
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.0
6.3
33
112
F44.81
ICD-10 Finland
Side person disorder
+∞
6.3
6
*
3138X
ICD-9 Finland
Disturbance of emotions specific to childhood and adolescence, Other or mixed emotional disturbances of childhood or adolescence[MUU MÄÄRITTELTY EMOTIONAALISENA OIREENA ILM. HÄIRIÖ]
+∞
6.3
6
*
2990A
ICD-9 Finland
Psychoses with origin specific to childhood, Infantile autism[AUTISMUS INFANTILIS,TÄYDELLINEN OIREYHTYMÄ]
+∞
6.3
6
*
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.8
6.3
19
40
T07
ICPC
Weight gain
4.2
6.2
22
54
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
0.2
6.2
8
333
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
3.9
6.1
23
60
SPAT1380
SPAT
Postpartum check-up
0.4
6.1
32
698
H52.1
ICD-10 Finland
Myopia
2.4
6.1
50
220
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
0.3
6.1
11
380
A03FA02
ATC
cisapride; oral, rectal
2.8
6.1
36
132
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
10.1
6.0
11
11
P86
ICPC
Anorexia nervosa/bulimia
6.1
6.0
15
25
K25
ICPC
Fear of hypertension
6.1
6.0
15
25
SPAT1053
SPAT
Memory test
5.6
6.0
16
29
T05
ICPC
Feeding problem of adult
4.6
6.0
19
42

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
192
588
3.82
54.13
1.7
1.6
1120.8
1145.5
nmol/l
0.14
152
446
787
5583
3.13
45.02
4.8
3.5
14.5
14.5
pmol/l
0.03
715
5086
164
521
3.58
43.23
2.1
3.4
—
—
—
0
0
423
2261
2.54
42.86
4.6
6.6
1.2
1.2
mmol/l
0.94
378
2090
350
1725
2.61
41.87
1.8
1.6
94.5
98.3
pmol/l
0.87
206
947
215
825
3.06
41.50
1.6
1.5
410.6
29356993.6
pmol/l
1.07
179
746
57
75
8.01
41.14
2.7
3.0
—
—
—
0
0
445
2495
2.44
39.91
5.4
6.8
1.2
1.2
mmol/l
0.40
367
2145
332
1629
2.57
39.73
2.2
2.7
2.4
2.4
mmol/l
0.43
296
1489
253
1090
2.78
39.26
2.9
2.3
—
—
—
0
0
848
6501
3.35
37.86
5.8
4.0
1.9
1.8
mu/l
1.43
794
6134
71
134
5.64
36.35
6.5
5.6
400.3
355.2
umol/l
1.54
62
123
221
931
2.78
35.45
1.5
1.3
18.6
18.9
nmol/l
0.09
198
830
864
6787
3.42
35.08
11.1
8.6
139.7
139.5
mmol/l
2.29
827
6553
784
5870
2.72
34.43
4.1
2.6
5.6
5.5
mmol/l
0.39
717
5465
863
6818
3.33
33.78
11.1
8.6
3.9
3.9
mmol/l
6.83
824
6554
643
4466
2.29
32.34
6.1
6.3
82.1
79.5
u/l
0.66
582
4218
430
2573
2.20
30.94
2.7
2.5
65.8
68.4
nmol/l
1.21
399
2428
199
851
2.68
30.63
2.2
3.3
—
—
—
0
0
116
402
3.14
26.08
3.5
3.2
—
—
—
0
0
204
994
2.33
23.20
2.0
2.4
—
—
—
0
0
152
683
2.45
20.58
2.1
2.0
343.7
382.8
nmol/l
1.84
145
631
290
1716
1.98
19.57
3.1
3.7
8.5
9.3
mmol/l
1.17
242
1536
265
1530
2.01
19.11
2.2
2.4
2.7
2.6
mg/l
0.39
220
1332
48
115
4.34
18.54
1.9
2.3
—
—
—
0
0
135
602
2.44
18.50
1.9
1.7
392.4
299.6
mu/l
1.77
109
532
511
3682
1.82
18.27
3.3
2.3
—
—
—
0
0
59
167
3.70
18.16
1.7
1.5
—
—
—
0
0
27
39
7.09
17.88
4.7
3.6
247.6
199.1
umol/l
0.22
16
17
331
2101
1.87
17.78
4.8
5.5
38.8
38.2
g/l
1.20
294
1965
35
1281
0.25
17.15
1.2
1.2
—
—
—
0
0
279
1694
1.91
17.08
2.7
2.7
55.1
56.3
u/l
0.23
248
1581
230
1315
1.98
16.79
2.6
2.0
320.1
287.9
u/l
0.10
218
1260
209
1186
1.97
15.46
2.2
2.3
—
—
—
0
0
233
1377
1.91
15.26
2.9
3.8
7.4
7.4
ph
0.77
47
277
879
7754
2.37
14.76
9.6
7.4
31.0
28.5
u/l
2.00
844
7512
23
35
6.71
14.52
1.7
2.3
15.4
14.5
umol/l
0.12
23
35
217
1275
1.90
14.38
2.1
2.3
—
—
—
0
0
217
1282
1.89
14.11
2.1
2.2
—
—
—
0
0
217
1285
1.89
14.00
2.2
2.3
—
—
—
0
0
385
2713
1.69
13.61
4.4
5.6
10.4
11.8
umol/l
1.21
347
2541
102
465
2.33
13.19
3.4
5.6
5.2
5.1
kpa
1.20
96
437
463
3444
1.66
13.17
4.3
4.6
6.1
6.2
mmol/l
0.58
425
3098
99
1955
0.45
13.02
1.5
1.6
—
—
—
0
0
101
464
2.31
12.83
3.4
5.6
7.4
7.4
ph
0.34
11
35
639
5185
1.68
12.73
4.2
3.3
36.3
36.8
mmol/mol
0.48
575
4936
607
4877
1.65
12.41
4.0
3.4
7.5
7.2
mm/h
0.27
545
4541
95
465
2.16
10.33
2.7
3.4
5.2
4.9
pmol/l
1.21
79
421
447
3443
1.55
10.07
9.8
8.1
0.0
0.0
e9/l
0.28
371
2760
200
1267
1.73
10.00
2.2
2.2
—
—
—
0
0
34
100
3.49
9.94
2.1
2.6
19.3
18.0
%
1.53
15
46
344
2506
1.58
9.86
7.2
6.8
—
—
—
0
0
209
1365
1.68
9.27
1.6
1.6
1.5
1.4
mmol/l
0.24
184
1230
335
2464
1.55
9.04
1.5
1.4
1.8
1.8
u/ml
0.02
82
609
9
434
0.20
8.99
1.4
1.4
—
—
—
0
0
9
436
0.20
8.97
1.4
1.5
—
—
—
0
0
70
321
2.27
8.93
8.0
8.1
1.0
1.1
inr
0.42
11
70
40
143
2.87
8.52
1.4
1.4
10.2
11.8
u/l
0.16
29
125
723
6310
1.57
8.40
3.6
2.9
4.6
4.6
mmol/l
0.41
674
6008
36
124
2.98
8.19
1.6
3.7
33.5
34.0
umol/l
0.06
30
109
521
4270
1.47
8.03
12.2
8.6
3.7
3.9
e9/l
0.89
464
3713
250
3389
0.65
7.92
2.4
2.2
—
—
—
0
0
129
773
1.77
7.74
5.0
7.7
1.1
1.2
mmol/l
0.19
122
724
125
745
1.78
7.64
2.2
2.2
10.1
13.6
nmol/l
3.35
107
674
34
120
2.90
7.43
1.7
7.2
23.5
23.9
mmol/l
0.27
27
107
59
273
2.24
7.40
1.2
1.3
—
—
—
0
0
687
5998
1.49
7.33
3.2
2.7
1.3
1.2
mmol/l
2.94
630
5703
663
7406
0.67
7.32
15.0
10.8
335.0
335.5
g/l
0.58
658
7340
26
79
3.35
7.28
1.5
5.4
—
—
—
0
0
453
3666
1.44
7.16
3.0
2.8
67.0
74.2
ug/l
0.61
405
3476
27
725
0.35
7.12
1.2
1.3
—
—
—
0
0
871
8048
1.78
7.11
11.4
7.8
—
—
—
0
0
92
510
1.89
7.09
3.2
3.3
0.2
0.2
g/l
0.81
80
476
149
2222
0.61
7.05
2.1
1.9
—
—
—
0
0
714
6311
1.49
6.92
3.7
2.9
2.9
2.8
mmol/l
0.61
663
5950
709
6264
1.48
6.84
3.6
2.8
1.3
1.4
mmol/l
6.97
660
5944
15
532
0.27
6.76
1.3
1.5
—
—
—
0
0
10
445
0.22
6.57
1.5
1.5
—
—
—
0
0
473
3900
1.41
6.53
8.2
7.0
0.2
0.2
e9/l
1.39
418
3474
113
686
1.73
6.47
1.8
2.4
2.4
2.4
mmol/l
2.94
93
591
14
29
4.88
6.46
2.4
2.7
—
—
—
0
0
22
65
3.44
6.44
2.4
1.6
91.1
91.6
%
0.19
22
65
219
1568
1.51
6.36
2.8
2.3
14.1
35.3
ng/l
0.87
101
601
33
126
2.68
6.28
2.3
3.4
—
—
—
0
0
458
3781
1.40
6.15
7.8
6.7
0.0
0.0
e9/l
0.06
401
3320
245
1811
1.47
6.05
6.4
6.7
—
—
—
0
0
457
3778
1.39
6.05
7.8
6.6
0.5
0.5
e9/l
1.73
404
3314
166
1133
1.56
5.98
2.2
2.5
574.0
590.1
mosm/kgh2o
0.28
147
993
216
1564
1.49
5.90
2.8
2.8
1.0
1.0
kg/l
0.34
19
221
284
2178
1.43
5.73
1.5
1.5
2.0
2.0
g/l
0.17
146
1343
123
792
1.63
5.64
1.8
2.4
14.9
15.3
umol/l
0.19
114
742
84
488
1.79
5.60
1.6
1.7
8.2
6.9
u/l
0.52
70
389
33
134
2.51
5.58
3.3
4.3
2.2
2.3
mmol/l
0.03
22
76
67
364
1.90
5.53
3.2
4.2
1.2
1.2
mmol/l
1.94
53
317
69
380
1.88
5.46
4.1
5.6
—
—
—
0
0
473
3980
1.37
5.41
7.6
6.5
2.1
2.0
e9/l
0.49
426
3558
185
2511
0.68
5.41
1.8
1.7
—
—
—
0
0
222
1643
1.45
5.38
5.3
4.5
1.1
1.1
inr
0.00
103
597
234
1758
1.44
5.22
2.9
3.0
0.0
0.0
estimate
0.80
91
697
62
336
1.90
5.17
3.0
2.7
—
—
—
0
0
119
786
1.59
4.92
5.1
5.4
0.8
0.8
mmol/l
1.21
113
742
112
730
1.60
4.90
1.8
2.3
2.5
2.5
g/l
0.13
99
680
431
3635
1.33
4.60
8.2
6.8
7.9
8.2
%
1.02
403
3459
58
320
1.86
4.60
4.0
6.2
9.7
9.6
kpa
0.11
53
303
81
496
1.69
4.53
6.3
4.7
0.0
0.0
%
1.24
23
125
83
512
1.68
4.51
6.2
4.6
0.5
0.6
%
0.12
24
132
138
961
1.51
4.50
4.1
4.7
5.7
15.0
mg/mmol
2.12
81
703
427
3607
1.33
4.47
8.1
6.6
2.6
2.9
%
1.85
397
3418
133
923
1.51
4.41
3.1
3.8
40.9
161.2
mg/l
1.09
79
672
78
480
1.68
4.29
6.4
4.8
0.0
0.0
%
0.74
21
109
9
13
6.97
4.17
5.7
11.7
—
—
—
0
0
99
655
1.57
4.08
1.7
2.4
24.0
25.0
%
0.23
82
586
25
104
2.44
4.08
1.8
1.7
—
—
—
0
0
410
3480
1.31
4.02
8.3
6.7
0.7
0.6
%
0.06
382
3306
41
211
1.98
4.02
1.8
1.6
0.3
0.4
nmol/l
1.23
35
177
440
3776
1.30
3.96
7.8
6.3
53.9
54.2
%
0.23
411
3600
23
94
2.48
3.90
1.3
1.3
0.8
1.3
promille
0.70
13
71
225
1764
1.36
3.80
2.8
2.9
123.0
58.4
e6/l
0.26
176
1335
445
3842
1.29
3.76
8.0
6.5
32.1
31.7
%
0.34
415
3664
147
1079
1.43
3.67
1.3
1.2
28.3
18.6
iu/ml
0.36
23
290
70
439
1.64
3.61
4.5
8.0
1.8
1.4
mmol/l
0.77
64
412
44
245
1.83
3.45
2.0
2.6
0.1
0.1
e6/l
1.14
44
235
75
485
1.59
3.43
4.8
4.2
0.1
0.4
%
2.50
20
99
105
733
1.48
3.40
1.2
1.2
61.4
135.4
iu/ml
3.56
38
275
90
610
1.52
3.36
3.5
6.6
1.4
1.5
mmol/l
0.11
70
482
10
27
3.73
3.36
1.0
1.1
—
—
—
0
0
30
148
2.06
3.33
1.8
2.4
161.0
206.0
ug/l
0.31
25
137
810
7650
1.35
3.06
10.4
9.1
18.1
20.7
mg/l
1.61
549
5569
53
324
1.67
3.05
3.4
5.8
54.0
69.5
ng/l
1.99
46
306
122
896
1.41
3.04
1.4
1.2
—
—
—
0
0
137
1029
1.39
3.00
1.3
1.4
350.6
482.0
titre
0.60
17
164
30
157
1.94
2.87
1.4
1.6
—
—
—
0
0
121
897
1.40
2.87
2.9
2.6
4.2
2.9
e6/l
0.61
72
459
13
314
0.41
2.82
1.2
1.1
—
—
—
0
0
217
2634
0.77
2.82
1.6
1.7
—
—
—
0
0
53
332
1.63
2.80
1.6
1.4
—
—
—
0
0
921
8926
1.58
2.74
18.3
12.9
266.5
258.4
e9/l
3.54
887
8671
74
1058
0.67
2.72
1.5
1.5
—
—
—
0
0
51
321
1.62
2.66
1.8
3.5
66.9
69.6
e9/l
0.20
36
214
225
2695
0.79
2.59
2.2
2.0
—
—
—
0
0
921
8938
1.56
2.58
18.2
12.8
29.6
29.7
pg
1.45
897
8819
921
8939
1.56
2.56
18.2
12.8
88.1
88.4
fl
1.25
897
8818
6
11
5.48
2.54
1.0
4.6
—
—
—
0
0
921
8941
1.55
2.53
18.3
12.8
4.8
4.7
e12/l
2.51
888
8672
98
718
1.41
2.50
1.8
3.9
5.9
7.2
umol/l
0.57
79
591
153
1203
1.32
2.50
3.6
3.9
—
—
—
0
0
512
4634
1.22
2.48
3.6
3.5
—
—
—
0
0
60
400
1.53
2.47
1.2
1.2
—
—
—
0
0
94
687
1.41
2.44
2.6
1.6
—
—
—
0
0
921
8948
1.54
2.44
18.4
13.0
140.2
139.5
g/l
0.77
897
8824
73
509
1.47
2.43
1.7
1.6
11.6
14.4
iu/l
0.53
61
408
10
252
0.39
2.43
1.2
1.1
—
—
—
0
0
921
8951
1.53
2.40
18.5
12.9
6.7
6.7
e9/l
0.14
887
8683
10
250
0.39
2.39
1.2
1.1
—
—
—
0
0
248
2906
0.80
2.32
4.0
3.9
—
—
—
0
0
16
72
2.24
2.28
1.1
1.1
—
—
—
0
0
6
13
4.64
2.27
1.2
2.4
—
—
—
0
0
36
218
1.68
2.21
2.9
2.9
77.3
106.1
ng/l
0.40
30
177
467
4221
1.20
2.20
3.8
3.4
275.7
144.2
e6/l
—
6
45
89
657
1.39
2.20
2.6
3.2
—
—
—
0
0
193
1592
1.26
2.19
3.0
2.8
0.3
0.3
e6/l
0.06
143
1173
148
1184
1.29
2.15
2.1
2.5
6.7
8.2
e6/l
0.44
129
1058
89
660
1.38
2.15
1.2
1.2
—
—
—
0
0
176
1442
1.27
2.12
2.3
2.1
—
—
—
0
0
8
25
3.22
2.09
1.4
1.3
128.3
140.7
nmol/l
—
8
25
23
124
1.88
2.08
1.3
2.6
142.2
137.3
g/l
0.55
17
91
5
10
5.02
2.07
1.2
1.1
—
—
—
0
0
728
6888
1.23
2.04
15.2
11.2
13.2
13.1
%
0.21
707
6753
79
580
1.39
2.03
2.0
2.3
26.0
119.9
u/l
0.58
66
485
12
50
2.42
2.03
1.3
1.2
—
—
—
0
0
35
548
0.63
2.02
1.3
1.3
367.6
249.1
miu/ml
—
8
271
9
32
2.83
2.00
4.0
1.5
1.6
1.1
nmol/l
—
9
25
70
505
1.42
1.99
2.8
4.8
1.4
1.6
%
0.80
57
464
23
127
1.83
1.95
1.7
1.4
339.7
354.9
ug/g
—
10
69
64
458
1.43
1.91
1.2
1.2
—
42.5
—
0
13
167
1378
1.26
1.90
2.5
2.9
156.2
115.6
ug/g
0.53
101
1094
0
53
0.00
1.87
0.0
1.1
—
—
—
0
0
256
2223
1.21
1.79
3.6
3.3
63.1
72.6
e6/l
0.08
188
1444
220
1883
1.22
1.78
6.0
4.4
—
—
—
0
0
19
102
1.88
1.77
1.7
9.1
—
—
—
0
0
765
7959
0.82
1.77
12.6
9.6
40.7
41.2
%
1.03
519
6863
6
18
3.35
1.75
1.2
3.1
2.7
4.8
nmol/l
—
6
18
74
558
1.35
1.66
5.6
8.7
—
—
—
0
0
107
851
1.29
1.65
2.7
2.6
166.1
970.4
ng/l
2.18
51
411
7
25
2.81
1.65
1.0
1.4
—
—
—
0
0
12
56
2.16
1.61
1.3
1.5
—
—
—
0
0
123
999
1.26
1.61
1.3
1.2
7.6
6.6
u/ml
0.08
42
400
12
57
2.12
1.55
1.5
1.2
108.0
51.8
u/l
0.23
12
52
98
778
1.29
1.55
2.5
2.5
1.2
1.1
ug/l
0.18
82
710
27
169
1.61
1.53
2.1
2.1
—
—
—
0
0
5
15
3.34
1.52
1.0
1.0
—
—
—
0
0
10
202
0.49
1.47
1.4
1.1
—
—
—
0
0
119
1426
0.81
1.35
2.6
2.1
—
—
—
0
0
22
138
1.61
1.27
1.1
1.8
—
—
—
0
0
14
77
1.83
1.26
1.4
2.3
—
—
—
0
0
6
25
2.41
1.24
1.2
1.2
—
—
—
0
0
9
45
2.01
1.23
1.1
1.2
—
—
—
0
0
12
63
1.92
1.23
1.0
1.0
—
—
—
0
0
34
238
1.44
1.22
1.9
1.8
3.7
7.2
ug/l
1.38
28
206
51
384
1.35
1.21
1.8
1.7
33.7
36.1
nmol/l
0.33
51
378
159
1829
0.84
1.18
2.4
2.3
—
—
—
0
0
59
754
0.77
1.17
1.8
1.3
—
—
—
0
0
26
174
1.51
1.16
1.0
1.1
—
—
—
0
0
8
39
2.06
1.15
1.0
1.5
31.4
31.9
pg
—
8
39
22
142
1.56
1.15
3.4
5.6
—
—
—
0
0
0
36
0.00
1.14
0.0
1.4
—
—
—
0
0
16
96
1.68
1.10
1.1
2.7
—
—
—
0
0
24
351
0.68
1.10
1.8
1.4
—
—
—
0
0
25
362
0.68
1.09
2.1
2.3
—
—
—
0
0
5
21
2.39
1.09
2.6
2.4
—
—
—
0
0
40
296
1.37
1.07
1.5
1.7
—
—
—
0
0
16
97
1.66
1.07
1.3
1.3
—
—
—
0
0
16
252
0.63
1.04
1.6
1.6
1.2
1.2
g/l
0.01
16
237
12
68
1.77
1.00
1.0
1.1
—
—
—
0
0
0
30
0.00
0.97
0.0
8.7
—
—
—
0
0
48
373
1.30
0.96
6.0
9.6
1.4
0.6
mmol/l
0.60
35
296
20
133
1.51
0.95
1.3
1.3
5.8
4.5
u/ml
—
10
60
75
620
1.23
0.91
2.3
2.6
10.0
10.3
g/l
0.36
66
568
16
243
0.65
0.91
1.6
1.6
0.2
0.2
g/l
0.14
16
230
184
1647
1.14
0.89
2.9
2.8
—
—
—
0
0
6
29
2.08
0.89
1.0
1.8
—
—
—
0
0
193
2134
0.88
0.85
1.8
1.7
—
—
—
0
0
60
489
1.24
0.84
1.6
1.8
1.0
1.2
g/l
1.14
50
455
171
1530
1.14
0.84
3.6
4.4
96.0
92.9
%
0.98
160
1500
15
97
1.55
0.81
1.5
1.4
—
—
—
0
0
19
130
1.47
0.81
1.4
1.3
114.0
44.6
pmol/l
0.50
19
124
6
33
1.82
0.79
1.5
2.1
—
—
—
0
0
15
98
1.54
0.78
1.3
1.3
2.3
2.9
g/l
—
10
70
15
98
1.54
0.78
1.3
1.3
0.2
0.4
g/l
—
10
71
15
98
1.54
0.78
1.3
1.3
4.7
6.4
g/l
—
10
71
25
182
1.38
0.78
3.6
7.3
—
—
—
0
0
18
125
1.45
0.73
1.3
1.2
—
—
—
0
0
10
60
1.67
0.72
1.4
1.3
—
—
—
0
0
21
151
1.40
0.71
5.4
3.1
—
—
—
0
0
97
1110
0.86
0.71
3.0
2.5
313.9
3078.9
umol/l
2.33
74
1028
10
61
1.65
0.68
1.2
1.2
—
—
nmol/l
—
0
0
7
118
0.59
0.68
1.1
1.7
—
—
—
0
0
29
373
0.77
0.67
1.1
1.1
1.3
3.2
u/ml
0.94
11
110
5
28
1.79
0.66
4.4
3.1
—
—
—
0
0
25
189
1.33
0.65
1.1
1.1
—
—
—
0
0
67
573
1.18
0.62
1.6
1.5
—
—
—
0
0
21
275
0.76
0.57
2.8
2.9
5.2
5.9
umol/l
0.24
15
217
8
54
1.49
0.57
1.4
1.3
—
73.5
—
0
6
18
241
0.74
0.57
1.0
1.0
0.0
0.5
u/ml
—
7
71
6
36
1.67
0.56
1.5
2.0
3.9
3.9
mmol/l
—
6
36
6
36
1.67
0.56
1.5
2.0
106.7
105.9
mmol/l
—
6
36
5
86
0.58
0.56
1.0
1.3
—
—
—
0
0
9
132
0.68
0.52
2.6
1.9
—
—
—
0
0
9
132
0.68
0.52
1.1
1.1
—
—
—
0
0
22
280
0.78
0.50
1.2
1.6
—
—
—
0
0
16
213
0.75
0.50
1.0
1.1
—
—
—
0
0
21
162
1.30
0.50
1.3
1.7
0.5
0.7
g/l
1.70
15
126
218
2041
1.09
0.50
2.3
2.5
—
—
—
0
0
11
155
0.71
0.48
2.7
2.5
—
—
—
0
0
13
93
1.40
0.48
2.0
2.4
—
—
—
0
0
7
46
1.53
0.48
1.0
1.1
200.6
201.9
iu/ml
—
7
46
353
3373
1.07
0.48
2.9
2.8
0.0
0.0
estimate
0.00
89
694
10
68
1.48
0.47
1.1
1.2
—
—
—
0
0
350
3347
1.07
0.46
2.9
2.8
0.0
0.0
estimate
0.50
85
689
350
3349
1.07
0.46
3.9
3.9
0.0
0.0
estimate
0.50
95
723
5
83
0.60
0.46
1.0
1.2
—
—
—
0
0
7
51
1.38
0.44
1.1
1.4
1.8
1.2
nmol/l
—
7
42
9
130
0.69
0.43
1.6
4.3
4.7
5.4
u/ml
—
9
112
29
239
1.22
0.43
7.6
10.4
0.7
0.7
%
0.08
29
239
147
1364
1.09
0.42
2.1
2.2
0.7
1.0
mg/l
1.51
91
907
23
185
1.25
0.42
2.3
4.7
2.9
5.3
ug/l
0.72
16
136
21
167
1.26
0.42
1.3
1.3
—
3.1
—
0
16
21
167
1.26
0.42
3.2
4.3
51.1
53.9
%
0.54
21
167
8
58
1.38
0.41
6.5
13.6
11.6
11.0
mmol/l
—
8
47
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
4.2
—
16.6
—
0
6
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
7.9
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
8
59
1.36
0.41
6.5
13.4
110.0
105.4
mmol/l
—
8
48
29
241
1.21
0.40
7.6
10.3
1.1
1.3
%
1.45
29
241
11
148
0.74
0.39
1.2
1.1
—
—
—
0
0
27
323
0.83
0.38
1.1
1.1
—
—
—
0
0
5
36
1.39
0.38
24.0
7.5
—
—
—
0
0
30
352
0.85
0.35
1.2
1.5
205.9
189.6
u/ml
—
7
200
13
99
1.32
0.35
1.8
2.8
1.3
1.3
e9/l
—
6
56
6
44
1.37
0.34
1.8
1.7
8.2
5.8
mmol/l
—
6
35
37
425
0.87
0.34
2.0
1.9
0.5
0.6
ug/l
0.29
21
166
20
163
1.23
0.34
3.3
4.1
3.2
3.7
e9/l
0.58
20
163
66
729
0.90
0.34
1.2
1.4
—
—
—
0
0
12
91
1.32
0.34
2.5
1.5
—
—
—
0
0
12
91
1.32
0.34
2.5
1.5
—
—
—
0
0
12
91
1.32
0.34
2.5
1.5
—
—
—
0
0
12
91
1.32
0.34
2.5
1.5
—
—
—
0
0
6
47
1.28
0.32
2.7
2.2
—
—
—
0
0
11
143
0.77
0.32
1.1
1.3
—
—
—
0
0
24
202
1.19
0.31
1.1
2.3
3.5
3.5
mmol/l
0.12
24
190
7
54
1.30
0.30
63.0
35.3
7.5
7.1
ug/l
—
7
49
25
214
1.17
0.28
1.6
1.8
3.0
5.4
iu/l
—
8
84
8
65
1.23
0.27
1.8
1.6
—
—
—
0
0
22
187
1.18
0.26
1.1
2.6
—
—
—
0
0
90
839
1.08
0.26
2.2
2.5
6938.5
5051.4
u/l
0.11
25
326
50
453
1.11
0.26
1.3
1.4
—
—
—
0
0
91
849
1.08
0.26
1.7
1.6
—
—
—
0
0
5
72
0.69
0.26
1.0
1.1
—
—
—
0
0
5
74
0.67
0.26
1.6
1.3
—
—
—
0
0
11
138
0.79
0.25
4.9
2.9
22.6
23.8
mg/l
—
6
86
22
188
1.17
0.25
9.7
12.4
—
—
—
0
0
24
276
0.87
0.24
1.1
1.1
0.8
7.7
u/ml
4.69
13
126
39
433
0.90
0.24
1.2
1.2
3.2
1.9
u/ml
0.30
20
210
17
200
0.85
0.23
1.0
1.1
—
—
—
0
0
18
153
1.18
0.22
1.1
1.1
233.2
156.9
iu/ml
—
6
57
7
95
0.73
0.22
1.4
1.1
—
8.4
—
0
20
13
107
1.22
0.21
1.2
1.3
24.1
57.7
pmol/l
—
8
26
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
75
799
0.93
0.20
1.6
2.0
—
—
—
0
0
21
240
0.87
0.20
1.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
50
1.20
0.19
2.7
15.1
13.8
12.5
%
—
6
50
11
90
1.22
0.19
3.8
4.6
—
—
—
0
0
11
90
1.22
0.19
1.0
1.1
—
—
—
0
0
6
53
1.13
0.18
1.0
1.6
—
6.8
—
0
15
35
382
0.91
0.17
1.1
1.1
0.7
1.2
u/ml
0.39
19
213
80
758
1.06
0.17
2.1
2.0
—
—
—
0
0
36
392
0.92
0.17
1.1
1.1
4.8
8.5
u/ml
0.69
22
259
19
215
0.88
0.17
1.2
1.1
—
8.8
—
0
19
5
70
0.71
0.16
1.0
1.0
—
7.9
—
0
11
12
101
1.19
0.16
1.0
3.8
—
—
—
0
0
9
81
1.11
0.15
2.3
3.9
—
—
—
0
0
19
169
1.13
0.14
8.1
5.4
—
—
—
0
0
7
86
0.81
0.14
1.1
1.1
149.7
260.7
mg/l
—
7
73
7
86
0.81
0.14
1.9
1.2
—
—
—
0
0
7
86
0.81
0.14
1.0
1.0
—
—
—
0
0
24
218
1.10
0.13
1.2
2.4
309.7
425.4
mg/l
1.85
24
206
67
637
1.06
0.13
1.1
1.1
—
—
—
0
0
13
114
1.14
0.12
1.0
1.2
0.2
3.0
u/ml
—
7
57
65
621
1.05
0.11
1.1
1.2
—
90.0
—
0
19
67
642
1.05
0.11
1.4
1.3
181.5
309.5
u/ml
1.36
61
585
51
485
1.05
0.11
1.3
1.2
—
—
—
0
0
163
1669
0.97
0.10
1.8
1.7
—
—
—
0
0
23
249
0.92
0.10
1.0
1.1
5.9
8.6
u/ml
0.36
12
125
5
44
1.14
0.10
13.8
4.4
—
—
—
0
0
6
54
1.11
0.09
1.0
1.7
—
—
—
0
0
6
54
1.11
0.09
3.7
6.8
9.5
9.3
mg/l
—
6
48
47
450
1.05
0.08
2.2
2.0
3.6
4.0
e9/l
0.64
31
396
25
234
1.07
0.08
5.1
4.9
0.5
0.3
g/l
0.31
16
142
7
85
0.82
0.07
1.7
1.1
—
—
—
0
0
11
100
1.10
0.05
1.0
1.0
—
—
—
0
0
26
248
1.05
0.05
1.7
1.7
—
—
—
0
0
32
308
1.04
0.04
1.2
1.3
—
—
—
0
0
10
92
1.09
0.03
2.2
2.6
—
40.1
—
0
9
21
201
1.05
0.03
1.1
2.4
11.0
14.2
e6/l
0.13
16
150
147
1478
0.99
0.01
3.3
2.7
—
—
—
0
0
22
214
1.03
0.00
2.5
2.2
—
—
—
0
0
46
466
0.99
0.00
1.0
1.1
—
—
—
0
0
23
226
1.02
0.00
1.7
1.8
—
4.0
—
0
5
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
8.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
2.0
—
0
6
0
5
0.00
0.00
0.0
1.0
—
81.2
—
0
5
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
0.4
—
0
5
6
60
1.00
0.00
1.5
2.9
22.3
26.0
%
—
6
60
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
48.3
—
0
7
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
50
1.00
0.00
17.8
4.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: F5_AUTISM – Autism

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).