Other lesions of median nerve

G6_MEDLEOTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G56.1
  • Hospital discharge: ICD-9 3541
  • Hospital discharge: ICD-8 35701
  • Cause of death: ICD-10 G56.1
  • Cause of death: ICD-9 3541
  • Cause of death: ICD-8 35701

2 out of 7 registries used, show all original rules.

1067

4. Check minimum number of events

None

1067

5. Include endpoints

None

1067

6. Filter based on genotype QC (FinnGen only)

1031

Control definitions (FinnGen only)

Control exclude
G6_NERPLEX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G56
Name in latin
Alia morbositas nervi mediani

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9440 6480 2874
Only index persons 7476 5256 2220
Unadjusted period prevalence (%)
Whole population 0.15 0.19 0.08
Only index persons 0.16 0.19 0.08
Median age at first event (years)
Whole population 50.58 50.84 49.78
Only index persons 48.51 49.05 47.24

-FinnGen-

Key figures

All Female Male
Number of individuals 1031 696 335
Unadjusted period prevalence (%) 0.22 0.25 0.15
Median age at first event (years) 46.56 45.88 47.98

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1067
Matched controls
10670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G56.0
ICD-10 Finland
Carpal tunnel syndrome
41.9
307.7
354
125
G56.1
ICD-10 Finland
Other lesions of median nerve
5092.6
307.7
484
*
35701
ICD-8 Finland
Other diseases of peripheral nerves except autonomic, Nervi mediani
+∞
307.7
546
*
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
103.6
307.3
159
18
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
140.4
269.5
135
11
ACC51
NOMESCO Finland
Release of median nerve
606.4
249.6
238
5
G56.2
ICD-10 Finland
Lesion of ulnar nerve
77.4
171.1
92
13
N03AX12
ATC
[U] gabapentin; oral
3.9
75.0
277
882
N03AX16
ATC
[U] pregabalin
3.4
74.2
371
1439
3540A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Carpal tunnel syndrome
+∞
73.8
70
*
G54.0
ICD-10 Finland
Brachial plexus disorders
28.4
60.4
41
15
N02AX02
ATC
tramadol; systemic, rectal
2.8
58.7
573
3136
ACC53
NOMESCO Finland
Release of ulnar nerve
+∞
50.4
48
*
M48.0
ICD-10 Finland
Spinal stenosis
3.2
46.6
214
765
3541A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Other lesion of median nerve
+∞
43.0
41
*
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
8.0
42.0
58
76
WX120
NOMESCO Finland
Intravenous local anesthesy of arm
14.2
40.1
37
27
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
39.6
540
3262
M79.6
ICD-10 Finland
Pain in limb
2.3
37.3
513
3087
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.5
36.8
323
1601
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.2
36.4
162
564
XA402
NOMESCO Finland
ENMG
8.2
35.6
48
61
G56.3
ICD-10 Finland
Lesion of radial nerve
98.5
34.9
38
*
L11
ICPC
Wrist symptom/complaint
3.4
31.8
126
407
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.3
31.8
305
1558
M65.3
ICD-10 Finland
Trigger finger
4.8
31.7
74
163
N06AA09
ATC
amitriptyline; systemic
3.0
31.1
154
568
M54.4
ICD-10 Finland
Lumbago with sciatica
2.5
29.5
217
980
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.7
29.0
175
717
M03BX02
ATC
tizanidine; oral
2.1
27.8
651
4616
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.6
27.1
94
278
N06AX21
ATC
duloxetine; oral
2.7
25.8
150
601
M02AA07
ATC
piroxicam; topical
2.0
25.2
449
2861
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
3.7
24.8
82
235
L12
ICPC
Hand/finger symptom/complaint
2.4
24.6
196
912
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.2
24.6
68
171
M01AH05
ATC
etoricoxib; oral
2.0
24.6
646
4680
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.2
24.6
102
338
M01AC06
ATC
meloxicam; systemic, rectal
1.9
23.7
435
2786
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
4.6
23.6
58
133
S18
ICPC
Laceration/cut
1.9
23.5
510
3450
M01AB05
ATC
diclofenac; systemic, rectal
2.0
23.4
701
5268
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
23.1
225
1139
H02AB06
ATC
prednisolone; systemic
1.9
22.7
533
3686
L03
ICPC
Low back symptom/complaint
2.0
22.6
311
1797
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
22.5
263
1430
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
22.1
215
1087
M54.5
ICD-10 Finland
Low back pain
1.9
22.0
392
2472
N02BE01
ATC
paracetamol; systemic, rectal
2.8
21.5
975
8416
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
6.5
21.5
35
55
ACC52
NOMESCO Finland
Release of radial nerve
+∞
20.9
20
*
M01AE02
ATC
naproxen; oral, rectal
1.8
20.3
595
4352
WX204
NOMESCO Finland
Axillary plexus blockaced
4.2
20.2
55
137
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
6.7
20.1
32
49
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
19.9
135
581
9502
FHL
Tendon splitting (De Quervain, click finger)
36.5
19.9
25
7
R4120
NOMESCO Finland
Occupational therapy
3.1
19.8
89
309
M25.5
ICD-10 Finland
Pain in joint
1.9
19.6
339
2100
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
6.2
19.1
33
55
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
3.0
19.1
89
315
M01AH02
ATC
rofecoxib; oral
2.2
19.0
174
854
1220
FHL
Arthroscopy
3.8
18.8
59
163
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.6
18.6
120
504
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
18.4
341
2151
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
18.4
427
2886
M47.9
ICD-10 Finland
Spondylosis, unspecified
4.5
18.4
45
103
L17
ICPC
Foot/toe symptom/complaint
1.9
18.3
319
1973
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.3
18.0
155
741
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
7.1
17.9
27
39
M01AH01
ATC
celecoxib; oral
2.0
17.6
223
1237
M01AE03
ATC
ketoprofen; systemic, rectal
1.8
17.5
420
2855
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.1
17.4
191
1004
N02BF01
ATC
gabapentin; oral
2.7
17.4
97
378
M01AX17
ATC
nimesulide; oral
1.9
17.2
294
1802
L15
ICPC
Knee symptom/complaint
1.9
17.0
268
1600
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
4.2
17.0
46
114
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.2
16.9
155
760
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.6
16.8
102
415
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
5.9
16.2
29
50
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.9
16.1
48
128
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.7
16.0
52
147
ZXA00
NOMESCO Finland
Right side
1.8
15.9
317
2031
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
4.0
15.8
45
116
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
15.7
371
2494
SPAT1153
SPAT
Removal of sutures
1.8
15.6
348
2300
M79.7
ICD-10 Finland
Fibromyalgia
3.8
15.6
48
131
J01DB01
ATC
cefalexin; oral
1.9
15.5
853
7229
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
15.5
203
1136
G51.0
ICD-10 Finland
Bell palsy
38.7
15.4
19
5
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.6
15.4
95
390
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.8
15.0
80
305
R03AC02
ATC
salbutamol; inhalant
1.7
15.0
565
4292
M03BC01
ATC
orphenadrine (citrate); systemic
1.9
15.0
225
1317
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.7
14.9
84
329
ZXA05
NOMESCO Finland
Left side
1.8
14.9
294
1871
L28
ICPC
Limited function/disability (L)
1.9
14.9
231
1366
L08
ICPC
Shoulder symptom/complaint
1.9
14.9
233
1382
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.2
14.8
132
638
N02AA05
ATC
oxycodone; systemic
1.9
14.8
221
1290
G56.4
ICD-10 Finland
Causalgia
+∞
14.6
14
*
X58
ICD-10 Finland
Exposure to other specified factors
2.1
14.3
147
751
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
4.6
14.3
34
76
G57.6
ICD-10 Finland
Lesion of plantar nerve
10.6
14.3
27
26
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.2
14.2
124
595
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.9
14.1
68
245
SPAT1254
SPAT
Administration of medicine
1.9
14.1
194
1101
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
14.0
508
3796
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.4
14.0
102
452
A10AB04
ATC
insulin lispro; parenteral
4.1
14.0
39
99
A10AE04
ATC
insulin glargine; parenteral
2.3
13.9
112
519
A02BC02
ATC
pantoprazole; systemic
1.7
13.9
721
5896
A02BC03
ATC
lansoprazole; oral
1.7
13.9
325
2166
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
13.6
87
363
9476
FHL
Splitting of fascia or aponeurosis
14.9
13.6
22
15
35700
ICD-8 Finland
Other diseases of peripheral nerves except autonomic, Nervi ulnaris
+∞
13.6
13
*
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
5.7
13.4
25
45
R60.0
ICD-10 Finland
Localized oedema
2.0
13.3
154
821
R06.0
ICD-10 Finland
Dyspnoea
1.7
13.3
304
2008
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
13.2
299
1969
SPAT1263
SPAT
Sampling
1.6
13.2
442
3223
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
13.2
117
564
G56.9
ICD-10 Finland
Mononeuropathy of upper limb, unspecified
40.6
13.2
16
*
C03CA01
ATC
furosemide; systemic
1.6
13.1
396
2813
J01AA02
ATC
doxycycline; systemic
1.8
13.1
820
6986
J01DA01
ATC
[U] cefalexin
1.6
13.1
644
5155
J46
ICD-10 Finland
Status asthmaticus
3.9
13.1
39
104
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
2.1
13.1
125
621
J01FF01
ATC
clindamycin; systemic
1.7
13.0
282
1833
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
12.9
139
723
A10AC01
ATC
insulin (human); parenteral
2.4
12.7
93
413
B01AB05
ATC
enoxaparin; parenteral
1.7
12.7
349
2416
N02BF02
ATC
pregabalin; oral
2.7
12.6
70
272
N02AC04
ATC
dextropropoxyphene; oral
2.9
12.6
58
204
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.7
12.5
67
256
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
12.5
87
378
L13
ICPC
Hip symptom/complaint
1.8
12.5
216
1315
R52.2
ICD-10 Finland
Other chronic pain
3.3
12.4
47
147
M23.8
ICD-10 Finland
Other internal derangements of knee
3.6
12.4
40
113
R51.80
ICD-10 Finland
Headache
1.9
12.2
157
868
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
5.3
12.0
24
46
N06AX11
ATC
mirtazapine; oral
1.6
12.0
357
2513
M01AB55
ATC
diclofenac, combinations; oral
2.3
12.0
91
410
73102
ICD-8 Finland
Inflammation of the synovial membrane, bursa and tendon sheath, Tendinivaginitis stenosans
21.6
12.0
17
8
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.1
12.0
130
676
A02BC01
ATC
omeprazole; systemic
1.7
12.0
299
2013
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
11.9
320
2197
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
11.8
259
1684
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
11.8
310
2114
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
11.8
394
2852
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
11.7
209
1282
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
16.6
11.7
18
11
WX203
NOMESCO Finland
Infraclavicular plexus blockade
4.2
11.6
31
76
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.6
11.6
68
272
M18.0
ICD-10 Finland
Primary arthrosis of first carpometacarpal joints, bilateral
5.3
11.6
23
44
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.7
11.6
278
1852
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.3
11.5
93
431
A03FA02
ATC
cisapride; oral, rectal
2.2
11.5
99
471
R05
ICPC
Cough
1.7
11.5
248
1604
35399
ICD-8 Finland
Sciatica
+∞
11.5
11
*
H02AB04
ATC
methylprednisolone; systemic
1.9
11.4
163
933
R42
ICD-10 Finland
Dizziness and giddiness
1.7
11.4
268
1774
M89.0
ICD-10 Finland
Algoneurodystrophy
15.2
11.3
18
12
L09
ICPC
Arm symptom/complaint
2.8
11.3
57
211
E66.01
ICD-10 Finland
Obesity due to excess calories
2.3
11.2
84
377
G47.3
ICD-10 Finland
Sleep apnoea
1.8
11.2
206
1274
T90
ICPC
Diabetes non-insulin dependent
1.7
11.1
257
1691
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
11.1
317
2201
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
3.5
11.1
37
107
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.6
11.0
64
255
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
11.0
97
466
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.2
11.0
90
420
E66.8
ICD-10 Finland
Other obesity
2.9
10.9
53
192
A02BC05
ATC
esomeprazole; systemic
1.6
10.9
414
3073
R20.2
ICD-10 Finland
Paraesthesia of skin
2.5
10.9
71
299
A06AD11
ATC
lactulose; oral
1.8
10.8
189
1150
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
10.8
170
1002
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
10.8
129
695
A02BA02
ATC
ranitidine; systemic
1.7
10.8
227
1456
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
2.9
10.8
50
177
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.6
10.7
61
241
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.1
10.6
45
151
A10AB01
ATC
insulin (human); parenteral
3.3
10.6
39
120
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
4.3
10.6
27
64
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
10.6
394
2908
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.1
10.5
44
147
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.7
10.4
33
92
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
10.4
269
1819
M77.1
ICD-10 Finland
Lateral epicondylitis
2.5
10.4
67
281
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
4.3
10.3
26
61
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
10.3
158
923
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.0
10.3
126
684
R13
ICD-10 Finland
Dysphagia
2.3
10.2
82
379
M01AX05
ATC
glucosamine; oral
1.7
10.2
240
1583
R03DC03
ATC
montelukast; oral
1.8
10.2
167
996
J01DA09
ATC
[U] cefadroxil
1.6
10.2
262
1769
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
10.2
358
2604
A10AB05
ATC
insulin aspart; parenteral
2.3
10.1
81
374
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
10.1
672
5603
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.1
10.1
104
531
9242
FHL
Other reconstruction or plastic surgery of shoulder joint (including ac joint)
5.1
10.1
21
42
Z02.7
ICD-10 Finland
Issue of medical certificate
2.2
10.0
82
382
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.0
10.0
44
151
T89
ICPC
Diabetes insulin dependent
3.1
10.0
41
135
A10AA01, ,
ATC
3.9
10.0
29
76
M16.1
ICD-10 Finland
Other primary coxarthrosis
1.9
9.9
138
782
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
9.9
251
1687
SPAT1211
SPAT
Application of soft bandage
2.1
9.8
101
515
SPAT1229
SPAT
Assessment of need for aid
2.1
9.8
99
502
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
3.9
9.7
28
73
J01CA04
ATC
amoxicillin; systemic
1.6
9.7
800
6964
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
9.7
208
1339
K02.1
ICD-10 Finland
Caries of dentine
1.5
9.6
523
4164
M02AA10
ATC
ketoprofen; topical
1.7
9.5
176
1087
A46
ICD-10 Finland
Erysipelas
1.8
9.5
153
908
3542A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Lesion of ulnar nerve
+∞
9.4
9
*
35708
ICD-8 Finland
Other diseases of peripheral nerves except autonomic, Alterius nervi
+∞
9.4
9
*
J01FA10
ATC
azithromycin; systemic
1.5
9.4
527
4214
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.7
9.4
50
191
AA1AD
NOMESCO Finland
CT of head and brain
1.6
9.3
301
2138
M54.3
ICD-10 Finland
Sciatica
2.4
9.3
63
270
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
4.6
9.3
22
49
SPAT1216
SPAT
Assessment of functional ability
1.7
9.2
191
1216
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
4.3
9.2
23
54
A01
ICPC
Pain general/multiple sites
2.0
9.1
103
543
WX002
NOMESCO Finland
Sedation and analgesia
1.7
9.1
206
1342
M67.4
ICD-10 Finland
Ganglion
2.3
9.1
67
299
-54
ICPC
Repair/fix-suture/cast/prosth device
3.6
9.0
29
82
M79.1
ICD-10 Finland
Myalgia
1.8
9.0
143
844
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.8
8.9
45
167
J45.1
ICD-10 Finland
Nonallergic asthma
2.1
8.9
81
394
SPAT1260
SPAT
Consultation of another employee
1.7
8.9
185
1178
A10AA02, ,
ATC
3.0
8.9
39
134
L90
ICPC
Osteoarthrosis of knee
2.1
8.9
80
388
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
12.7
8.9
15
12
NBG10
NOMESCO Finland
Acromioplastia
3.3
8.8
33
103
ACC19
NOMESCO Finland
Transcision of peripheral nerve: other or unspecified
50.4
8.7
10
*
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
8.7
106
575
M70.6
ICD-10 Finland
Trochanteric bursitis
1.8
8.7
147
884
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.0
8.6
24
61
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
8.6
184
1180
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.1
8.6
23
57
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
9.1
8.5
17
19
R02
ICPC
Shortness of breath/dyspnoea
1.8
8.5
141
842
A10BA02
ATC
metformin; oral
1.5
8.5
302
2185
M54.1
ICD-10 Finland
Radiculopathy
2.8
8.5
43
160
S17
ICPC
Abrasion/scratch/blister
3.6
8.4
27
76
N05CF01
ATC
zopiclone; oral
1.5
8.4
350
2618
SPAT1301
SPAT
No procedures
1.5
8.3
323
2379
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
8.3
424
3300
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.6
8.3
27
77
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
8.2
198
1307
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
8.2
335
2492
TQW40
NOMESCO Finland
Remowal of suture of skin
2.1
8.2
74
359
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
3.7
8.2
25
68
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
1.8
8.2
130
766
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.6
8.2
47
187
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.0
8.1
84
430
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
8.1
882
7964
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
2.9
8.1
36
125
R03BB04
ATC
tiotropium bromide; inhalant
1.9
8.1
111
626
G50.0
ICD-10 Finland
Trigeminal neuralgia
9.0
8.1
16
18
H3603, E103,
ICD-10 Finland
10.1
8.0
15
15
J01FA09
ATC
clarithromycin; systemic
1.5
7.9
285
2063
M15
ICD-10 Finland
Polyarthrosis
2.2
7.8
66
312
A10BJ02
ATC
liraglutide; parenteral
3.1
7.8
32
106
P01AB01
ATC
metronidazole; oral, rectal
1.5
7.8
391
3026
L14
ICPC
Leg/thigh symptom/complaint
2.0
7.8
87
458
UJF32
NOMESCO Finland
Coloscopy
1.5
7.7
268
1923
L86
ICPC
Back syndrome with radiating pain
2.3
7.7
60
274
NC1BG
NOMESCO Finland
Elbow MRI examination with high intensity magnet
15.1
7.7
12
8
160
Kela drug reimbursment
exenatide
3.5
7.7
26
76
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
3.5
7.7
26
76
R52.9
ICD-10 Finland
Pain, unspecified
1.9
7.7
98
540
M13.9
ICD-10 Finland
Arthritis, unspecified
2.1
7.6
70
343
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
7.6
657
5614
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
7.6
127
761
NHQ40
NOMESCO Finland
Amputation of toe
4.1
7.6
20
49
R96
ICPC
Asthma
1.9
7.5
100
558
73398
ICD-8 Finland
Other diseases of muscle, tendon and fascia, Alii definiti
7.2
7.5
17
24
SPAT1262
SPAT
Handing over of treatment supplies
1.6
7.4
177
1164
6451
FHL
Dilatation
6.5
7.4
18
28
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.0
7.4
85
451
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
3.8
7.4
22
59
A10AE06
ATC
insulin degludec; parenteral
2.8
7.3
36
132
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.1
7.3
68
334
ZXD20
NOMESCO Finland
Day surgery
1.7
7.3
127
768
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.3
7.3
52
229
WX320
NOMESCO Finland
Spinalanesthesy
1.5
7.3
248
1770
2505A
ICD-9 Finland
Diabetes mellitus, Diabetes with ophthalmic manifestations[NEUROPATHIA DIABETICA,TYYPPI II]
+∞
7.3
7
*
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
+∞
7.3
7
*
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
3.5
7.3
24
69
M01AH03
ATC
valdecoxib; oral
2.2
7.3
63
301
E66.9
ICD-10 Finland
Obesity, unspecified
2.8
7.3
35
127
A08
ICPC
Swelling
2.1
7.3
64
308
NDF25
NOMESCO Finland
Operation for osteochondritis of joint of wrist, arthroscopic
15.9
7.2
11
7
SPAT1325
SPAT
Vaccination
1.5
7.2
352
2700
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
2.4
7.2
48
205
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
1.9
7.2
85
456
SPAT1097
SPAT
Recording of ECG
1.6
7.2
160
1035
M22.4
ICD-10 Finland
Chondromalacia patellae
3.2
7.2
28
90
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
3.6
7.2
23
65
R03AC03
ATC
terbutaline; inhalant
1.7
7.1
139
868
L04AX03
ATC
methotrexate; systemic
1.9
7.1
96
538
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
7.1
276
2025
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
7.1
100
569
M65.4
ICD-10 Finland
Radial styloid tenosynovitis [de Quervain]
3.1
7.0
28
91
L16
ICPC
Ankle symptom/complaint
1.8
7.0
108
630
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
7.0
275
2023
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
6.9
72
369
R07.3
ICD-10 Finland
Other chest pain
1.8
6.9
110
648
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
6.9
649
5578
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.9
388
3048
M09AX01
ATC
hyaluronic acid; parenteral
2.1
6.9
64
314
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.8
6.8
103
598
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.7
6.8
123
752
J01FA06
ATC
roxithromycin; oral
1.4
6.8
392
3094
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.2
6.8
53
243
S97
ICPC
Chronic ulcer skin
2.0
6.8
71
365
L88
ICPC
Rheumatoid/seropositive arthritis
2.4
6.8
44
186
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.8
6.7
96
548
T92.4
ICD-10 Finland
Sequelae of injury of nerve of upper limb
22.7
6.7
9
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
6.7
172
1152
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
6.7
276
2047
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
6.6
486
3993
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
2.8
6.6
31
111
H70
ICPC
Otitis externa
3.1
6.6
26
84
M50.3
ICD-10 Finland
Other cervical disc degeneration
3.1
6.6
26
84
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
12.3
6.6
11
9
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.8
6.6
32
117
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
6.6
462
3768
A97
ICPC
No disease
1.6
6.6
170
1140
SFA30
NOMESCO Finland
Three-surface restoration
1.4
6.5
372
2924
XQ800
NOMESCO Finland
Prick test
2.1
6.5
60
294
J02AC01
ATC
fluconazole; systemic
1.4
6.5
361
2824
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
6.5
194
1344
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.5
386
3058
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.8
6.4
95
548
G58.7
ICD-10 Finland
Mononeuritis multiplex
70.3
6.4
7
*
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
6.4
88
496
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
14.4
6.4
10
7
R01AD09
ATC
mometasone; nasal
1.4
6.4
399
3185
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
6.4
104
618
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
6.3
202
1418
R52.1
ICD-10 Finland
Chronic intractable pain
8.2
6.3
13
16
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.7
6.3
131
831
G44.2
ICD-10 Finland
Tension-type headache
1.7
6.3
122
760
73109
ICD-8 Finland
Synovitis, bursitis and tenosynovitis, Unspecified
5.6
6.3
17
31
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
6.3
240
1748
9481
FHL
Detachment or severance of a muscle or tendon
9.3
6.3
12
13
N03AF01
ATC
carbamazepine; oral, rectal
2.2
6.3
49
225
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.7
6.3
33
126
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.3
465
3818
3548X
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Other mononeuritis of upper limb
+∞
6.3
6
*
3543A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Lesion of radial nerve
+∞
6.3
6
*
G54.1
ICD-10 Finland
Lumbosacral plexus disorders
+∞
6.3
6
*
NF1AA
NOMESCO Finland
Hip X-ray examination
1.8
6.2
101
599
7270X
ICD-9 Finland
Other disorders of synovium, tendon and bursa, Synovitis and tenosynovitis[TENOSYNOVITIS ALIA LOCO DEFINITO]
26.8
6.2
8
*
ND1DG
NOMESCO Finland
Wrist and hand very extensive MRI examination with high intensity magnet
26.8
6.2
8
*
G57.8
ICD-10 Finland
Other mononeuropathies of lower limb
26.8
6.2
8
*
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.2
6.2
52
246
K59.0
ICD-10 Finland
Constipation
2.0
6.2
65
335
C08CA13
ATC
lercanidipine; oral
1.6
6.2
161
1080
XQ802
NOMESCO Finland
Epicutan test
2.5
6.2
38
157
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.6
6.2
34
133
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
6.2
169
1148
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
2.8
6.2
30
110
H02BX01
ATC
methylprednisolone, combinations; systemic
2.0
6.2
61
308
Z3226
NOMESCO Finland
Physiotherapist
1.5
6.1
179
1232
7263A
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of elbow region[EPICONDYLITIS LATERALIS HUMERI]
7.7
6.1
13
17
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.2
6.1
48
221
A07EC01
ATC
sulfasalazine; oral, rectal
1.9
6.1
78
430
S46.1
ICD-10 Finland
Injury of muscle and tendon of long head of biceps
4.1
6.1
16
39
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.4
6.0
40
171
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
2.7
6.0
31
117
J01MA12
ATC
levofloxacin; systemic
1.5
6.0
183
1271
H01
ICPC
Ear pain/earache
1.8
6.0
96
567
R05FB02
ATC
cough suppressants and expectorants; systemic
1.4
6.0
379
3023
A10BK03
ATC
empagliflozin; oral
1.8
6.0
92
537

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
532
3918
1.71
16.36
2.6
2.5
—
—
—
0
0
383
2660
1.69
14.06
2.2
2.1
151.89
222.36
u/l
1.60
358
2488
760
6322
1.70
13.50
5.1
4.0
13.38
13.68
mm/h
0.23
703
5740
468
3451
1.63
13.44
4.4
3.8
39.87
49.69
ng/l
0.38
355
2517
574
4504
1.59
12.38
7.1
6.2
1.22
1.22
mmol/l
0.04
498
3782
634
5116
1.59
11.95
4.9
4.5
7.24
6.74
mmol/l
4.13
609
4781
542
4245
1.56
11.43
15.7
17.1
1.30
1.29
inr
0.04
142
1189
309
2126
1.64
11.28
2.7
2.6
355.45
8464.13
umol/l
9.53
260
1832
786
6757
1.62
10.64
7.4
7.2
76.90
80.00
u/l
1.66
740
6279
164
961
1.83
10.62
2.0
1.6
—
—
—
0
0
368
2674
1.57
10.58
2.3
2.4
51.40
61.72
u/l
3.72
337
2435
363
2633
1.57
10.50
3.3
3.1
6.94
6.91
mmol/l
0.04
303
2180
351
2531
1.58
10.39
3.4
3.1
292.02
234.27
mg/l
0.10
219
1547
521
4114
1.52
10.13
6.5
5.5
1.22
1.21
mmol/l
0.21
474
3676
501
3944
1.51
9.76
4.9
4.5
34.79
35.04
g/l
0.44
453
3651
189
1183
1.73
9.73
2.1
1.9
—
—
—
0
0
694
5865
1.52
9.49
5.4
4.9
2160.75
1936.98
e6/l
0.04
12
101
363
2704
1.52
9.02
4.1
3.6
14.26
8.45
mg/mmol
0.77
219
1622
101
540
1.96
8.62
3.7
3.4
5.32
5.20
kpa
0.73
96
512
100
533
1.97
8.61
3.7
3.4
7.39
7.40
ph
—
8
63
366
2756
1.50
8.53
2.2
2.3
—
—
—
0
0
379
2878
1.49
8.46
3.1
3.1
1649.23
1520.44
ng/l
0.23
323
2459
485
3874
1.46
8.34
6.2
6.0
—
—
—
0
0
528
4290
1.46
8.29
6.0
5.7
0.20
0.18
e9/l
1.03
474
3720
198
1309
1.63
8.20
1.3
1.2
27.16
36.21
iu/ml
0.59
62
435
291
2104
1.53
8.17
2.1
2.2
—
—
—
0
0
755
6591
1.50
8.05
4.4
4.0
14.97
14.98
pmol/l
0.04
674
5895
698
6000
1.47
8.04
5.4
4.6
—
—
—
0
0
189
1252
1.62
7.73
1.3
1.2
16.73
13.23
u/ml
0.25
67
473
924
8473
1.68
7.58
19.1
14.7
23.26
24.83
mg/l
0.77
785
6754
459
3677
1.44
7.53
2.4
2.2
79.57
78.59
nmol/l
0.27
393
3217
312
2322
1.49
7.53
2.4
2.1
3.07
3.13
mg/l
0.18
267
1950
68
331
2.13
7.50
4.0
3.7
24.30
24.99
mmol/l
0.86
63
301
587
4919
1.43
7.50
7.9
8.7
4.32
4.15
e9/l
1.01
513
4285
325
2445
1.47
7.41
4.4
4.0
—
—
—
0
0
153
973
1.67
7.34
1.3
1.3
429.09
585.49
titre
0.95
33
204
472
3819
1.42
7.24
2.2
2.0
90.62
94.50
pmol/l
0.82
207
1865
504
4137
1.41
7.07
5.9
5.4
0.61
0.59
e9/l
1.00
444
3541
505
4147
1.41
7.07
5.9
5.4
0.04
0.04
e9/l
0.68
446
3555
251
1814
1.50
6.92
1.6
1.6
1.16
1.25
mg/l
0.21
197
1398
404
3214
1.41
6.67
2.7
3.4
2.36
2.36
mmol/l
0.19
342
2768
75
398
1.95
6.57
3.6
3.4
—
—
—
0
0
509
4245
1.38
6.22
5.9
5.5
1.93
1.87
e9/l
0.18
465
3725
252
1860
1.46
6.18
5.2
4.5
1.01
1.02
kg/l
0.21
41
265
539
4569
1.36
5.80
5.2
6.0
10.46
11.71
umol/l
2.95
510
4310
116
733
1.65
5.69
4.2
3.2
104.24
89.11
ng/l
0.81
93
614
342
2709
1.39
5.57
4.6
3.7
7.39
7.40
ph
1.13
64
508
101
621
1.69
5.50
1.6
2.3
—
—
—
0
0
56
287
2.00
5.45
3.2
3.1
0.25
0.25
g/l
0.01
18
109
191
1369
1.48
5.38
2.2
1.9
29.82
29.66
s
0.15
186
1321
466
3895
1.35
5.35
6.0
5.6
2.81
2.75
%
0.23
432
3610
502
4246
1.34
5.31
4.4
4.0
0.00
0.00
estimate
0.50
101
850
467
3915
1.34
5.21
6.3
5.9
8.64
8.73
%
0.20
432
3634
453
3783
1.34
5.18
6.1
5.7
0.64
0.66
%
0.40
420
3496
81
478
1.75
5.12
2.8
3.0
4.24
4.48
pmol/l
1.11
67
409
943
8870
1.54
4.91
22.4
17.4
139.49
139.60
mmol/l
0.64
918
8596
232
1755
1.41
4.88
4.0
3.8
207.59
350.56
ng/l
0.88
187
1437
283
2218
1.38
4.81
1.6
1.6
19.79
20.76
nmol/l
0.48
230
1833
160
1133
1.48
4.77
7.1
4.7
1.10
1.04
mmol/l
1.62
146
1013
596
5221
1.32
4.73
3.4
3.0
46.24
50.12
u/l
0.64
547
4753
209
2722
0.71
4.62
3.0
3.0
—
—
—
0
0
464
3942
1.31
4.52
5.9
5.5
58.42
57.99
%
0.31
428
3663
113
752
1.56
4.50
8.5
6.2
12.85
10.18
mmol/l
1.88
102
708
111
736
1.57
4.49
2.1
2.5
65.05
66.28
g/l
0.99
94
662
854
7918
1.39
4.46
5.6
4.8
1.88
2.13
mu/l
0.91
771
7126
942
8892
1.51
4.46
22.9
17.5
4.01
3.97
mmol/l
3.90
916
8607
501
4309
1.31
4.44
4.4
4.0
0.00
0.00
estimate
0.50
92
772
23
88
2.65
4.42
3.2
2.8
—
—
—
0
0
24
94
2.59
4.40
1.3
1.2
—
—
—
0
0
854
7923
1.39
4.40
7.2
5.8
41.91
40.09
mmol/mol
5.52
768
7222
469
4001
1.31
4.40
6.3
5.8
26.36
26.97
%
0.50
435
3719
404
3388
1.31
4.26
4.1
3.8
5.61
5.85
ph
0.59
14
208
162
1176
1.45
4.25
1.3
1.2
—
—
—
0
0
143
1014
1.47
4.23
6.1
7.0
0.87
1.22
mmol/l
0.36
111
801
495
4270
1.30
4.22
5.8
5.4
0.00
0.00
estimate
-0.00
97
771
39
194
2.05
4.17
1.5
1.5
24141.81
16305.75
e6/l
0.28
27
138
241
1882
1.36
4.13
1.9
1.8
1113.21
1221.92
nmol/l
0.99
179
1377
127
887
1.49
4.06
5.9
7.5
95.92
95.63
%
0.26
120
852
221
1707
1.37
4.05
1.2
1.2
1.73
1.61
u/ml
0.06
55
440
141
1010
1.46
3.97
6.2
7.1
12.60
11.98
kpa
0.67
132
959
141
1010
1.46
3.97
6.2
7.1
5.11
5.07
kpa
0.21
133
956
195
1481
1.39
3.96
1.4
1.4
2.45
2.48
g/l
0.08
114
866
26
113
2.33
3.87
1.5
3.0
—
—
—
0
0
283
2288
1.32
3.82
4.8
4.4
0.00
0.00
estimate
0.50
97
754
376
3170
1.29
3.69
3.8
3.7
96.86
121.01
e6/l
0.23
276
2257
142
1041
1.42
3.53
2.3
2.3
1.77
1.88
%
0.80
114
910
18
69
2.64
3.48
1.7
1.2
39513.91
151835.22
e6/l
0.60
11
50
70
445
1.61
3.42
7.8
3.1
23.79
24.02
mmol/l
0.22
70
436
86
574
1.54
3.42
1.1
1.1
—
—
—
0
0
252
2036
1.31
3.37
4.4
4.0
—
—
—
0
0
116
828
1.45
3.34
2.4
2.5
5.09
7.59
ug/l
1.73
90
708
238
1911
1.32
3.33
2.5
2.6
6.13
6.20
e6/l
0.03
216
1725
125
907
1.43
3.30
5.1
3.9
—
—
—
0
0
412
3553
1.26
3.28
3.4
2.7
114.45
132.59
ug/l
1.10
366
3201
269
2206
1.29
3.21
3.7
3.7
90.51
88.97
%
0.46
261
2146
114
825
1.43
3.06
3.5
2.9
211.56
252.22
ng/l
0.43
102
759
318
2682
1.26
3.01
4.8
3.9
—
—
—
0
0
162
1248
1.35
3.00
3.3
2.3
2.37
2.33
g/l
0.43
134
1145
369
3170
1.25
2.97
3.6
3.4
—
—
—
0
0
84
578
1.49
2.93
1.5
1.4
—
—
—
0
0
26
128
2.06
2.93
1.5
1.4
—
—
—
0
0
175
1370
1.33
2.91
3.2
2.3
11.33
12.61
umol/l
1.85
152
1268
128
955
1.39
2.90
1.3
1.4
—
—
—
0
0
319
2715
1.25
2.76
3.4
3.2
23.05
89.52
e6/l
1.88
260
2093
152
1179
1.34
2.70
3.4
2.3
19.99
22.13
%
1.10
121
1006
16
67
2.41
2.64
1.0
1.1
—
—
—
0
0
174
1381
1.31
2.63
3.0
3.2
0.81
0.82
mmol/l
0.43
165
1280
76
525
1.48
2.62
2.6
3.2
6.17
5.90
e9/l
0.04
55
402
124
938
1.36
2.59
2.1
2.6
6.14
9.26
umol/l
1.47
114
819
33
187
1.79
2.51
1.1
1.2
13.44
2.30
u/ml
—
8
20
101
743
1.40
2.50
3.7
3.6
—
—
—
0
0
42
256
1.67
2.49
1.4
1.4
279.95
286.20
ug/g
0.06
22
140
66
449
1.50
2.47
7.0
9.7
—
—
—
0
0
13
51
2.57
2.45
1.5
1.4
—
—
—
0
0
110
828
1.37
2.38
6.3
7.8
119.90
119.44
g/l
0.07
104
804
19
91
2.11
2.34
2.1
2.2
—
—
—
0
0
104
780
1.37
2.31
2.1
2.4
67.84
72.00
e9/l
0.65
74
598
938
9030
1.32
2.31
12.1
10.3
24.43
24.61
u/l
0.14
899
8630
54
359
1.53
2.27
1.7
1.9
1.40
2.25
ug/l
0.37
45
310
18
86
2.11
2.23
1.3
1.6
56.89
62.66
%
—
9
59
68
476
1.46
2.23
2.7
2.5
—
—
—
0
0
77
552
1.43
2.23
8.0
7.5
24.41
24.46
mmol/l
0.04
71
522
23
122
1.90
2.17
1.1
1.4
—
—
—
0
0
302
2616
1.22
2.15
3.5
3.0
28.34
34.76
u/l
3.70
283
2464
26
145
1.81
2.12
1.3
1.5
—
—
—
0
0
45
292
1.56
2.11
1.9
3.4
58.37
73.00
mg/l
0.22
39
234
45
292
1.56
2.11
1.9
3.4
33.47
51.98
mg/l
0.81
39
235
80
584
1.40
2.11
5.5
5.2
—
—
—
0
0
913
8785
1.27
2.05
18.8
14.1
—
—
—
0
0
44
287
1.56
2.03
1.8
3.4
1.52
1.84
ratio
—
7
24
9
32
2.83
2.00
3.4
2.7
3381.00
1458.41
u/ml
—
9
32
28
163
1.74
2.00
1.8
2.0
4.59
4.83
mmol/24h
0.12
22
140
654
6104
1.18
1.96
4.3
3.9
—
—
—
0
0
18
91
1.99
1.96
1.7
1.4
—
—
—
0
0
10
39
2.58
1.94
1.7
1.4
—
—
—
0
0
966
9374
1.32
1.94
27.9
21.8
7.07
6.73
e9/l
1.86
930
9045
5
11
4.56
1.94
1.4
1.5
—
—
—
0
0
118
930
1.30
1.91
1.3
1.3
—
—
—
0
0
53
366
1.47
1.90
2.0
1.9
—
—
—
0
0
233
1992
1.22
1.88
1.8
1.7
89583793.19
15965235.51
pmol/l
0.57
192
1591
90
684
1.34
1.88
3.5
4.2
0.10
0.09
%
0.04
31
205
95
728
1.33
1.88
3.4
4.1
0.61
0.92
%
1.03
36
251
31
190
1.65
1.86
3.0
2.8
8.25
7.96
kpa
0.47
31
184
17
86
1.99
1.85
2.6
2.3
0.43
1.21
g/24h
—
7
39
221
1883
1.22
1.84
2.7
3.0
2.43
2.46
mmol/l
1.66
188
1671
858
8228
1.22
1.81
4.8
4.4
1.44
1.50
mmol/l
3.36
774
7409
27
161
1.69
1.79
1.0
1.2
42.19
7.44
e6/l
0.40
16
124
27
161
1.69
1.79
1.0
1.3
204.74
198.45
e6/l
0.01
19
130
114
903
1.29
1.79
1.7
2.2
156.05
135.59
ug/g
0.39
80
703
86
655
1.34
1.78
3.2
4.0
0.45
0.61
%
0.51
31
210
964
9370
1.30
1.76
27.9
21.8
250.70
249.92
e9/l
0.14
934
9078
93
719
1.32
1.74
1.5
1.5
—
—
—
0
0
9
36
2.51
1.74
2.2
2.7
43055.56
38236.25
ug/l
—
9
36
964
9373
1.30
1.73
27.8
21.7
91.36
91.34
fl
0.04
943
9191
277
2426
1.19
1.72
3.2
3.1
—
—
—
0
0
964
9374
1.29
1.72
27.8
21.7
30.29
30.31
pg
0.10
943
9190
884
8514
1.22
1.72
5.4
5.0
2.62
2.73
mmol/l
2.96
798
7677
964
9375
1.29
1.71
27.9
21.8
4.38
4.41
e12/l
1.09
927
9049
23
133
1.75
1.71
1.5
2.1
—
—
—
0
0
42
284
1.50
1.69
1.2
1.2
0.66
1.69
u/ml
—
5
18
964
9378
1.29
1.68
28.1
21.9
131.85
132.90
g/l
1.37
944
9196
867
8341
1.21
1.66
5.4
4.6
6.25
5.96
mmol/l
5.36
776
7433
6
19
3.17
1.66
1.0
1.2
—
—
—
0
0
6
19
3.17
1.66
1.0
1.2
—
—
—
0
0
6
19
3.17
1.66
1.0
1.2
—
—
—
0
0
13
62
2.11
1.66
1.1
1.3
—
—
—
0
0
7
25
2.81
1.65
1.0
1.0
1525.71
1812.60
miu/ml
—
7
25
109
869
1.28
1.64
4.4
3.2
1.84
1.86
mmol/l
0.02
94
725
94
735
1.31
1.64
7.1
6.9
—
—
—
0
0
963
9372
1.28
1.64
27.8
21.8
39.42
39.40
%
0.03
885
8703
24
143
1.69
1.62
1.0
1.2
—
—
—
0
0
10
42
2.39
1.62
1.7
1.5
0.82
1.05
promille
—
10
31
8
32
2.51
1.60
1.5
1.5
—
—
—
0
0
14
70
2.01
1.59
1.2
1.3
—
—
—
0
0
42
289
1.47
1.57
1.5
2.0
21.14
21.16
s
0.01
37
257
83
643
1.32
1.56
3.2
4.2
0.00
0.13
%
1.39
22
166
32
209
1.55
1.52
3.1
2.3
—
—
—
0
0
11
51
2.17
1.51
1.8
1.1
—
—
—
0
0
16
86
1.87
1.51
1.1
1.3
—
—
—
0
0
862
8311
1.19
1.49
4.9
4.4
4.55
4.66
mmol/l
2.23
785
7536
46
326
1.43
1.49
1.2
2.2
9.23
10.31
g/l
1.25
40
281
30
196
1.55
1.44
2.0
2.1
93.58
66.39
ug/min
0.18
14
121
17
95
1.80
1.43
1.8
1.4
—
—
—
0
0
250
2206
1.17
1.42
1.7
1.6
1.56
1.35
mmol/l
1.45
213
1826
281
2506
1.16
1.39
3.3
3.1
0.29
0.53
e6/l
1.55
225
1914
7
29
2.42
1.39
1.0
1.8
—
—
—
0
0
53
394
1.36
1.33
1.2
1.2
—
—
—
0
0
12
61
1.98
1.33
1.1
1.3
0.26
0.43
g/l
—
5
43
12
61
1.98
1.33
1.1
1.3
6.74
7.21
g/l
—
5
43
11
54
2.05
1.33
3.3
1.8
—
—
—
0
0
94
760
1.26
1.30
5.0
3.6
1.22
1.23
mmol/l
0.33
81
643
31
210
1.49
1.29
2.1
3.8
—
—
—
0
0
12
62
1.95
1.28
1.8
1.4
27.70
29.26
%
—
5
39
39
278
1.42
1.26
1.2
2.2
38.28
37.21
g/l
0.44
32
235
211
1856
1.17
1.25
2.8
2.9
527.88
529.21
mosm/kgh2o
0.03
186
1594
6
25
2.41
1.24
1.2
1.2
—
—
—
0
0
247
2201
1.16
1.23
5.6
6.4
—
—
—
0
0
92
749
1.25
1.21
1.6
2.0
364.70
390.30
nmol/l
0.63
80
674
33
230
1.45
1.21
1.3
1.4
38.66
30.34
iu/l
0.57
26
198
28
189
1.49
1.19
2.2
2.1
125.74
125.78
g/l
0.00
19
141
102
842
1.23
1.19
2.5
2.2
27.00
37.43
u/l
2.40
92
710
18
109
1.66
1.19
1.6
1.3
1920.33
1341.14
e6/l
0.42
12
78
37
265
1.41
1.18
6.9
7.7
1.58
1.35
mmol/l
0.60
31
231
0
34
0.00
1.16
0.0
1.4
—
—
—
0
0
18
110
1.65
1.16
1.2
1.1
1.60
5.67
u/ml
—
5
46
13
72
1.82
1.15
2.0
2.7
—
—
—
0
0
30
208
1.46
1.14
1.8
1.6
2.45
4.98
iu/l
1.88
12
65
99
820
1.23
1.13
1.8
1.6
—
—
—
0
0
240
2148
1.15
1.13
1.3
1.4
—
—
—
0
0
39
286
1.38
1.10
10.9
10.2
—
—
—
0
0
90
742
1.23
1.08
3.2
2.5
4.63
4.49
kpa
0.25
85
715
823
7969
1.14
1.07
4.3
3.9
1.42
1.28
mmol/l
5.73
738
7101
119
1011
1.20
1.07
1.8
1.7
—
—
—
0
0
18
113
1.60
1.06
2.2
1.8
177.28
208.28
pmol/l
0.81
18
107
19
121
1.58
1.06
2.0
2.5
—
—
—
0
0
23
154
1.50
1.04
3.3
2.8
—
—
—
0
0
16
98
1.64
1.03
1.6
1.4
48071.75
95019.50
e6/l
—
8
56
9
47
1.92
1.02
12.0
12.8
—
—
—
0
0
86
712
1.23
1.01
1.8
1.5
—
—
—
0
0
19
123
1.55
1.00
1.6
2.1
—
—
—
0
0
9
49
1.84
0.98
1.1
1.7
13.11
12.17
umol/l
—
9
44
71
578
1.24
0.97
2.5
2.9
10.46
10.64
g/l
0.14
62
522
26
182
1.44
0.96
3.8
3.6
—
—
—
0
0
58
462
1.27
0.96
1.7
1.7
1.33
1.42
g/l
0.14
52
413
20
133
1.51
0.94
1.1
1.3
—
—
—
0
0
15
93
1.62
0.94
8.2
5.3
7.80
7.70
mmol/l
—
10
77
6
27
2.23
0.93
4.8
1.9
29.65
337.00
ug/l
—
6
22
6
27
2.23
0.93
1.5
2.9
—
—
—
0
0
72
591
1.23
0.93
3.6
3.2
—
—
—
0
0
12
70
1.72
0.92
1.5
1.2
—
—
—
0
0
224
2030
1.13
0.89
4.8
4.9
2.01
3.19
ug/l
1.96
206
1808
371
3468
1.11
0.85
2.2
2.1
—
—
—
0
0
15
96
1.57
0.84
2.2
3.3
—
—
—
0
0
26
188
1.39
0.83
4.0
4.1
2.54
2.87
mmol/l
0.24
20
125
8
46
1.74
0.82
2.6
2.0
10.34
10.11
mmol/l
—
8
46
6
32
1.88
0.82
1.3
1.2
—
—
—
0
0
246
2257
1.12
0.80
3.9
3.7
—
—
—
0
0
5
98
0.51
0.78
1.4
1.2
—
—
—
0
0
6
34
1.77
0.76
1.7
5.2
—
—
—
0
0
169
1521
1.13
0.76
2.9
2.7
1.08
1.52
e6/l
0.59
96
861
15
99
1.52
0.76
2.0
1.7
—
—
—
0
0
14
92
1.53
0.72
2.4
4.4
—
—
—
0
0
9
56
1.61
0.72
1.0
1.1
—
—
—
0
0
10
60
1.67
0.72
1.2
1.1
—
—
—
0
0
12
76
1.59
0.72
1.1
1.0
4.46
4.31
u/ml
—
5
32
30
386
0.77
0.69
1.4
1.4
—
—
—
0
0
44
356
1.25
0.68
4.3
4.2
—
—
—
0
0
14
94
1.50
0.67
1.1
1.2
—
—
—
0
0
5
28
1.79
0.66
1.2
1.6
15.20
14.77
pmol/l
—
5
20
13
86
1.52
0.66
1.2
1.1
1.23
1.73
u/ml
—
8
44
5
29
1.73
0.64
1.2
1.1
11.20
14.54
g/l
—
5
22
21
155
1.36
0.63
5.7
2.6
—
—
—
0
0
8
49
1.64
0.62
1.3
1.5
—
—
—
0
0
30
236
1.28
0.60
2.8
2.8
—
—
—
0
0
34
272
1.26
0.60
3.5
3.3
—
—
—
0
0
20
148
1.36
0.60
1.6
2.2
—
—
—
0
0
8
53
1.51
0.58
1.5
1.8
34.90
37.95
%
—
8
53
6
35
1.72
0.57
1.0
1.0
—
—
—
0
0
156
1427
1.11
0.56
3.1
2.8
5.79
3.23
e6/l
1.21
86
774
94
835
1.14
0.55
1.7
2.0
0.19
0.21
g/l
0.87
87
773
96
858
1.13
0.52
1.9
1.6
—
—
—
0
0
21
161
1.31
0.52
1.6
2.1
—
—
—
0
0
21
162
1.30
0.50
1.7
2.1
—
—
—
0
0
21
162
1.30
0.50
1.6
2.1
—
—
—
0
0
17
222
0.76
0.47
1.2
1.1
—
—
—
0
0
59
514
1.16
0.47
1.3
1.4
—
—
—
0
0
5
82
0.61
0.46
1.8
1.5
—
—
—
0
0
8
119
0.67
0.46
1.3
1.2
—
—
—
0
0
109
992
1.11
0.45
2.7
4.2
21.53
27.05
ug/l
0.11
84
818
7
50
1.40
0.45
1.7
3.2
—
—
—
0
0
12
86
1.40
0.44
1.2
1.8
—
—
—
0
0
9
127
0.71
0.43
1.2
1.2
—
—
—
0
0
5
31
1.62
0.43
2.2
2.3
—
—
—
0
0
22
273
0.80
0.43
5.8
5.0
—
—
—
0
0
12
87
1.38
0.42
1.8
1.4
271.83
272.05
mosm/kgh2o
—
6
62
5
32
1.57
0.42
1.2
1.4
—
—
—
0
0
10
139
0.72
0.42
3.3
2.5
—
—
—
0
0
8
58
1.38
0.41
1.1
1.3
—
—
—
0
0
8
59
1.36
0.41
3.1
3.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
23
186
1.24
0.40
1.4
1.2
—
—
—
0
0
48
549
0.87
0.40
1.4
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
5.6
—
—
—
0
0
25
205
1.22
0.39
1.3
1.6
—
—
—
0
0
51
448
1.15
0.38
1.6
1.6
—
—
—
0
0
9
67
1.35
0.38
1.0
1.2
—
—
—
0
0
20
161
1.25
0.37
1.5
1.9
—
—
—
0
0
53
469
1.14
0.36
1.3
1.4
—
—
—
0
0
9
71
1.27
0.36
1.0
1.1
—
—
—
0
0
5
79
0.63
0.35
1.8
1.4
—
—
—
0
0
5
79
0.63
0.35
1.8
1.4
—
—
—
0
0
6
43
1.40
0.35
3.5
6.3
—
—
—
0
0
6
45
1.34
0.33
1.0
1.2
225.08
150.41
pmol/l
—
6
45
45
507
0.88
0.32
4.1
3.8
—
—
—
0
0
27
315
0.85
0.31
1.5
1.8
—
—
—
0
0
32
368
0.87
0.31
3.2
3.2
5531.19
10789.81
u/ml
0.24
26
317
7
57
1.23
0.29
3.9
2.7
—
—
—
0
0
13
103
1.27
0.28
1.2
1.8
0.38
0.89
g/l
—
7
81
21
177
1.19
0.27
3.0
2.5
15.30
15.82
%
0.22
12
86
387
3763
1.04
0.27
11.2
9.5
0.00
0.00
e9/l
1.28
328
3079
9
120
0.75
0.27
1.7
1.6
—
—
—
0
0
8
65
1.23
0.27
1.8
2.5
—
—
—
0
0
58
529
1.10
0.27
1.3
1.2
—
—
—
0
0
13
104
1.25
0.26
1.0
1.1
—
15.15
—
0
6
13
104
1.25
0.26
1.1
1.1
—
—
—
0
0
24
278
0.86
0.26
1.1
1.2
—
—
—
0
0
112
1055
1.07
0.25
1.3
1.3
—
—
—
0
0
67
724
0.92
0.24
4.5
4.1
—
—
—
0
0
732
7225
1.04
0.24
22.2
17.8
15.39
15.10
%
0.62
722
7071
55
504
1.10
0.24
1.1
1.2
70.61
144.54
iu/ml
1.57
20
189
6
85
0.70
0.24
1.2
1.2
—
—
nmol/l
—
0
0
5
40
1.25
0.22
1.4
1.2
—
—
—
0
0
5
41
1.22
0.22
1.0
1.7
—
—
—
0
0
44
401
1.10
0.22
2.1
1.7
1.61
1.61
g/l
0.01
36
346
5
42
1.19
0.21
1.6
3.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
176.00
—
0
5
23
201
1.15
0.21
1.2
1.2
—
634.00
—
0
5
0
12
0.00
0.21
0.0
3.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
17.96
—
0
13
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
49.72
—
0
6
9
112
0.80
0.20
1.0
1.0
—
—
—
0
0
21
238
0.88
0.18
1.6
1.3
—
—
—
0
0
5
68
0.73
0.17
1.2
1.1
—
—
—
0
0
20
177
1.13
0.16
1.4
1.3
56.21
58.66
mmol/l
0.12
14
140
74
779
0.95
0.15
1.4
1.4
—
—
—
0
0
12
102
1.18
0.15
1.3
1.3
—
—
—
0
0
7
89
0.79
0.14
1.0
1.1
—
—
—
0
0
7
89
0.79
0.14
1.0
1.1
—
—
—
0
0
12
139
0.86
0.14
1.3
1.5
—
—
—
0
0
17
151
1.13
0.13
2.2
3.5
3.84
4.37
e9/l
0.49
17
151
9
110
0.82
0.13
1.0
1.0
—
—
—
0
0
35
326
1.08
0.12
2.5
2.6
—
—
—
0
0
21
231
0.91
0.12
1.1
1.1
—
—
—
0
0
12
136
0.88
0.11
1.6
1.3
—
—
—
0
0
28
260
1.08
0.11
3.3
3.3
0.88
0.81
nmol/l
0.22
22
213
121
1177
1.03
0.10
2.9
3.0
0.71
0.78
ug/l
0.37
77
793
17
154
1.11
0.10
1.5
1.7
1.15
0.82
nmol/l
0.40
11
126
5
47
1.06
0.09
1.0
1.0
294.00
289.22
mg/l
—
5
40
20
216
0.92
0.08
3.4
3.5
19.01
26.11
mg/l
0.47
11
133
6
74
0.81
0.07
4.2
3.5
29.26
16.04
mg/l
—
6
57
17
157
1.08
0.07
2.5
3.8
58.00
59.19
%
0.17
17
157
9
85
1.06
0.07
2.3
1.9
—
—
—
0
0
9
86
1.05
0.07
1.1
1.1
1.58
1.54
g/l
—
9
77
9
88
1.02
0.07
1.0
1.0
—
—
—
0
0
27
285
0.95
0.06
1.5
1.6
—
—
—
0
0
23
217
1.06
0.06
1.3
1.2
—
—
—
0
0
11
120
0.92
0.05
1.0
1.1
—
—
—
0
0
10
92
1.09
0.03
1.0
1.5
—
—
—
0
0
696
6977
0.99
0.03
24.9
19.4
330.86
331.30
g/l
0.65
687
6906
17
163
1.04
0.01
1.1
1.3
252.50
248.81
miu/ml
—
6
65
42
426
0.99
0.00
1.4
1.3
—
—
—
0
0
26
262
0.99
0.00
1.0
1.1
—
—
—
0
0
10
101
0.99
0.00
1.2
1.2
0.71
0.69
nmol/l
—
10
93
11
105
1.05
0.00
2.7
2.9
—
—
—
0
0
5
52
0.96
0.00
1.0
1.0
—
—
—
0
0
6
69
0.87
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
190.40
—
0
5
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
7
69
1.01
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.48
—
0
6
13
130
1.00
-0.00
1.5
1.1
720.80
279.68
u/ml
—
5
77
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
92
0.98
-0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.02
—
0
5
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint G6_MEDLEOTH and mortality.

Females

Parameter HR [95% CI] p-value
G6_MEDLEOTH 0.892 [0.75, 1.07] 0.212
Birth year 0.998 [0.99, 1.01] 0.646

During the follow-up period (1.1.1998 — 31.12.2019), 141 out of 1512 females with G6_MEDLEOTH died.

Males

Parameter HR [95% CI] p-value
G6_MEDLEOTH 1.025 [0.82, 1.28] 0.823
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 169 out of 1159 males with G6_MEDLEOTH died.

Mortality risk

Mortality risk for people of age

years, who have G6_MEDLEOTH.

N-year risk Females Males
1 0.081% 0.187%
5 0.625% 1.053%
10 1.59% 2.713%
15 2.958% 4.969%
20 5.052% 8.629%

Relationships between endpoints

Index endpoint: G6_MEDLEOTH – Other lesions of median nerve

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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