No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1036 |
4. Check minimum number of eventsNone |
1036 |
5. Include endpointsNone |
1036 |
6. Filter based on genotype QC (FinnGen only) |
1036 |
Control definitions (FinnGen only)
- Control exclude
- G6_NERPLEX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G56
- Name in latin
- Alia morbositas nervi mediani
Similar endpoints
↥List of similar endpoints to
Other lesions of median nerve
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9440 | 6480 | 2874 |
| Only index persons | 7476 | 5256 | 2220 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.19 | 0.08 |
| Only index persons | 0.16 | 0.19 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 50.58 | 50.84 | 49.78 |
| Only index persons | 48.51 | 49.05 | 47.24 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1036 | 698 | 338 |
| Unadjusted period prevalence (%) | 0.21 | 0.24 | 0.15 |
| Median age at first event (years) | 46.45 | 45.75 | 47.89 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 940
- Matched controls
- 9399
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
35701
ICD-8 Finland
Other diseases of peripheral nerves except autonomic, Nervi mediani
+∞
323.0
512
*
G56.1
ICD-10 Finland
Other lesions of median nerve
2249.1
323.0
394
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
51.8
239.0
287
79
ACC51
NOMESCO Finland
Release of median nerve
1193.8
202.9
191
*
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
252.4
148.7
149
7
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
145.3
109.8
115
9
3540A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Carpal tunnel syndrome
+∞
66.4
63
*
G56.2
ICD-10 Finland
Lesion of ulnar nerve
44.4
56.9
70
17
N03AX16
ATC
pregabalin; oral
3.3
50.2
317
1249
N03AX12
ATC
gabapentin; oral
3.9
47.6
225
700
N02AX02
ATC
tramadol; systemic, rectal
2.7
43.7
483
2676
3541A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Other lesion of median nerve
+∞
39.9
38
*
ACC53
NOMESCO Finland
Release of ulnar nerve
203.1
38.1
39
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
31.8
472
2876
M48.0
ICD-10 Finland
Spinal stenosis
3.1
27.7
175
653
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.5
26.2
132
418
XA402
NOMESCO Finland
ENMG
12.0
25.7
47
41
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.4
25.6
265
1322
N06AA09
ATC
amitriptyline; systemic
3.2
24.4
141
494
M79.6
ICD-10 Finland
Pain in limb
2.1
24.1
375
2245
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.4
23.3
245
1222
N02BE01
ATC
paracetamol; systemic, rectal
2.6
23.3
830
6994
M01AC06
ATC
meloxicam; systemic, rectal
2.1
23.2
392
2415
G54.0
ICD-10 Finland
Brachial plexus disorders
28.1
22.3
30
11
M03BX02
ATC
tizanidine; oral
1.9
21.3
555
4001
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
8.1
21.2
48
62
G56.3
ICD-10 Finland
Lesion of radial nerve
78.6
20.8
23
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.7
20.2
147
595
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
19.4
174
790
WX120
NOMESCO Finland
Intravenous local anesthesy of arm
16.0
19.4
31
20
M01AE02
ATC
naproxen; oral, rectal
1.9
18.9
516
3712
M01AB05
ATC
diclofenac; systemic, rectal
1.9
18.7
608
4639
N06AX21
ATC
duloxetine; oral
3.0
18.7
115
418
M54.4
ICD-10 Finland
Lumbago with sciatica
2.5
18.6
165
746
M25.5
ICD-10 Finland
Pain in joint
2.0
18.0
266
1520
L11
ICPC
Wrist symptom/complaint
3.3
17.7
92
297
M01AH05
ATC
etoricoxib; oral
1.8
17.3
529
3903
M65.3
ICD-10 Finland
Trigger finger
4.8
17.1
58
128
9502
FHL
Tendon splitting (De Quervain, click finger)
23.5
16.5
23
10
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.2
16.3
87
287
S18
ICPC
Laceration/cut
1.8
16.0
400
2734
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
15.9
298
1846
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
3.7
15.9
71
203
M02AA07
ATC
piroxicam; topical
1.8
15.8
383
2588
H02AB06
ATC
prednisolone; systemic
1.8
15.8
449
3198
L03
ICPC
Low back symptom/complaint
2.0
15.7
242
1393
M54.5
ICD-10 Finland
Low back pain
1.9
15.6
313
1983
ZXA00
NOMESCO Finland
Right side
1.9
15.1
281
1733
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
14.6
211
1181
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.3
14.4
73
232
M01AX17
ATC
nimesulide; oral
1.9
14.2
262
1604
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.2
13.9
158
799
L12
ICPC
Hand/finger symptom/complaint
2.3
13.9
142
681
J01AA02
ATC
doxycycline; systemic
1.8
13.7
718
6033
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
13.6
362
2488
SPAT1153
SPAT
Removal of sutures
1.8
13.5
315
2077
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
5.6
13.3
38
70
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.9
13.2
82
300
WX204
NOMESCO Finland
Axillary plexus blockaced
5.1
13.2
41
83
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
2.9
13.1
80
289
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.6
13.1
98
401
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
7.3
12.8
30
42
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.8
12.8
86
330
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
12.7
173
942
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.3
12.7
125
590
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.8
12.6
82
308
G51.0
ICD-10 Finland
Bell palsy
32.5
12.6
16
5
R03AC02
ATC
salbutamol; inhalant
1.7
12.6
467
3510
ACC52
NOMESCO Finland
Release of radial nerve
+∞
12.5
12
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.0
12.5
50
131
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
4.3
12.4
46
112
SPAT1263
SPAT
Sampling
1.7
12.4
391
2808
J01DA01
ATC
[U] cefalexin; systemic
1.6
12.1
569
4535
G56.4
ICD-10 Finland
Causalgia
47.3
11.9
14
*
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.9
11.8
72
260
SPAT1254
SPAT
Administration of medicine
2.0
11.8
166
914
1220
FHL
Arthroscopy
3.5
11.7
54
160
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
11.6
315
2152
R4120
NOMESCO Finland
Occupational therapy
2.9
11.5
72
265
M01AH01
ATC
celecoxib; oral (coxibs)
1.9
11.3
190
1114
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
4.6
11.2
38
85
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
5.8
11.2
31
55
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.4
11.2
54
166
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
20.3
11.1
16
8
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
11.1
105
484
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.3
11.0
110
522
R06.0
ICD-10 Finland
Dyspnoea
1.7
11.0
252
1634
WX110
NOMESCO Finland
Local anesthesy
1.6
11.0
568
4585
M01AH02
ATC
rofecoxib; oral
2.0
11.0
147
793
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
10.9
254
1652
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.1
10.8
41
103
G57.6
ICD-10 Finland
Lesion of plantar nerve
9.7
10.8
21
22
C03CA01
ATC
furosemide; systemic
1.7
10.7
322
2252
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
7.7
10.7
24
32
N02AC04
ATC
dextropropoxyphene; oral
3.3
10.7
53
167
ZXA05
NOMESCO Finland
Left side
1.7
10.6
257
1690
A02BC02
ATC
pantoprazole; systemic
1.6
10.6
596
4891
L15
ICPC
Knee symptom/complaint
1.8
10.6
200
1218
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.2
10.5
117
581
L17
ICPC
Foot/toe symptom/complaint
1.7
10.5
237
1527
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.1
10.4
123
626
35399
ICD-8 Finland
Sciatica
+∞
10.4
10
*
35700
ICD-8 Finland
Other diseases of peripheral nerves except autonomic, Nervi ulnaris
+∞
10.4
10
*
73102
ICD-8 Finland
Inflammation of the synovial membrane, bursa and tendon sheath, Tendinivaginitis stenosans
16.2
10.4
16
10
A10AE04
ATC
insulin glargine; parenteral
2.3
10.3
95
431
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
10.3
275
1857
E66.01
ICD-10 Finland
Obesity due to excess calories
2.7
10.3
69
266
J01DB01
ATC
cefalexin; oral
1.7
10.3
728
6320
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.5
10.3
81
341
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
10.2
75
304
A02BC03
ATC
lansoprazole; oral
1.7
10.2
284
1944
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.7
10.1
33
72
R51.80
ICD-10 Finland
Headache
2.1
10.1
125
653
N02AA05
ATC
oxycodone; systemic
1.9
10.1
160
918
R05
ICPC
Cough
1.8
9.9
198
1226
A06AD11
ATC
lactulose; oral
1.9
9.9
159
915
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
9.9
313
2209
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
16.9
9.9
15
9
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
9.9
283
1949
A10AA01
ATC
NA
5.5
9.9
28
52
A02BA02
ATC
ranitidine; systemic
1.8
9.9
205
1285
R52.2
ICD-10 Finland
Other chronic pain
3.8
9.8
40
108
J01FF01
ATC
clindamycin; systemic
1.7
9.8
235
1536
N06AX11
ATC
mirtazapine; oral
1.6
9.7
284
1962
A10AA02
ATC
NA
4.0
9.6
37
95
T89
ICPC
Diabetes insulin dependent
4.2
9.5
35
86
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.2
9.5
102
500
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.7
9.4
242
1613
9476
FHL
Splitting of fascia or aponeurosis
8.1
9.4
20
25
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.9
9.4
56
202
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
9.3
186
1150
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.6
9.3
41
119
N05CF01
ATC
zopiclone; oral
1.6
9.2
306
2181
M01AB55
ATC
diclofenac, combinations; oral
2.3
9.1
82
368
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
9.1
769
6840
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
9.1
175
1069
L13
ICPC
Hip symptom/complaint
1.8
8.9
159
944
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.5
8.9
68
283
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
8.9
398
3040
G50.0
ICD-10 Finland
Trigeminal neuralgia
12.7
8.9
15
12
H02AB04
ATC
methylprednisolone; systemic
1.9
8.8
143
825
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.4
8.8
75
331
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.3
8.8
80
364
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
8.7
109
570
A03FA02
ATC
cisapride; oral, rectal
2.2
8.7
89
425
NC1BG
NOMESCO Finland
Elbow MRI examination with high intensity magnet
50.4
8.7
10
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
8.7
215
1415
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
8.7
219
1449
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
2.0
8.5
107
561
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
90.8
8.4
9
*
E66.9
ICD-10 Finland
Obesity, unspecified
4.1
8.4
31
77
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
8.4
169
1043
A10AE06
ATC
insulin degludec; parenteral
4.4
8.4
29
68
35708
ICD-8 Finland
Other diseases of peripheral nerves except autonomic, Alterius nervi
+∞
8.3
8
*
3542A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Lesion of ulnar nerve
+∞
8.3
8
*
73398
ICD-8 Finland
Other diseases of muscle, tendon and fascia, Alii definiti
8.6
8.3
17
20
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.9
8.3
117
641
A02BC01
ATC
omeprazole; systemic
1.6
8.3
259
1812
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
8.1
134
775
M77.1
ICD-10 Finland
Lateral epicondylitis
2.6
8.1
56
221
NBG10
NOMESCO Finland
Acromioplastia
3.8
8.1
33
90
X58
ICD-10 Finland
Exposure to other specified factors
1.9
8.1
114
625
H3603, E103
ICD-10 Finland
NA
11.8
8.1
14
12
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.6
8.1
226
1535
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
4.2
8.0
29
71
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
8.0
76
354
M54.3
ICD-10 Finland
Sciatica
2.6
8.0
55
216
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.7
8.0
52
199
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.3
8.0
38
118
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.0
7.9
45
155
T90
ICPC
Diabetes non-insulin dependent
1.6
7.9
208
1387
M79.7
ICD-10 Finland
Fibromyalgia
3.6
7.9
34
97
R60.0
ICD-10 Finland
Localized oedema
1.9
7.9
120
675
A08
ICPC
Swelling
2.8
7.9
50
186
H70
ICPC
Otitis externa
5.2
7.9
23
45
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
13.2
7.9
13
10
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.3
7.9
38
119
M02AA10
ATC
ketoprofen; topical
1.8
7.9
152
929
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
3.2
7.8
39
125
J01CA04
ATC
amoxicillin; systemic
1.5
7.8
690
6046
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
7.8
346
2620
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
7.8
90
457
L08
ICPC
Shoulder symptom/complaint
1.7
7.8
168
1059
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
7.7
109
597
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
7.7
89
450
WX320
NOMESCO Finland
Spinalanesthesy
1.6
7.7
204
1360
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
4.8
7.7
24
51
R07.3
ICD-10 Finland
Other chest pain
2.1
7.6
89
455
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.3
7.6
67
300
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
7.6
289
2112
M89.0
ICD-10 Finland
Algoneurodystrophy
10.1
7.5
14
14
M23.8
ICD-10 Finland
Other internal derangements of knee
3.4
7.5
35
107
A01
ICPC
Pain general/multiple sites
2.2
7.5
74
349
G47.3
ICD-10 Finland
Sleep apnoea
1.7
7.5
158
990
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.1
7.5
83
412
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
7.5
100
538
SPAT1260
SPAT
Consultation of another employee
1.7
7.5
164
1040
SPAT1325
SPAT
Vaccination
1.5
7.4
323
2427
K02.1
ICD-10 Finland
Caries of dentine
1.5
7.4
426
3394
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
4.6
7.4
24
53
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
5.3
7.4
21
40
E66.8
ICD-10 Finland
Other obesity
2.9
7.3
43
154
B01AB05
ATC
enoxaparin; parenteral
1.5
7.3
280
2043
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.7
7.3
47
178
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
7.3
374
2906
2505A
ICD-9 Finland
Diabetes mellitus, Diabetes with ophthalmic manifestations[NEUROPATHIA DIABETICA,TYYPPI II]
+∞
7.3
7
*
9499
FHL
Other measure in this category
+∞
7.3
7
*
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.3
230
1604
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
7.2
317
2381
SPAT1301
SPAT
No procedures
1.5
7.2
284
2085
P01AB01
ATC
metronidazole; oral, rectal
1.5
7.2
339
2591
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.0
7.2
85
435
M47.9
ICD-10 Finland
Spondylosis, unspecified
3.3
7.2
34
106
NDF25
NOMESCO Finland
Operation for osteochondritis of joint of wrist, arthroscopic
20.2
7.1
10
5
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
4.1
7.1
26
65
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
4.6
7.1
23
51
A02BC05
ATC
esomeprazole; systemic
1.5
7.1
359
2777
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
5.4
7.1
20
38
M79.1
ICD-10 Finland
Myalgia
1.9
7.1
106
593
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.4
7.1
32
96
L28
ICPC
Limited function/disability (L)
1.7
7.1
166
1070
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
3.7
7.0
29
81
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.0
548
4621
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
7.0
177
1168
M16.1
ICD-10 Finland
Other primary coxarthrosis
1.8
6.9
114
660
M01AX05
ATC
glucosamine; oral
1.6
6.9
216
1501
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.8
6.9
42
156
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.6
6.8
212
1469
R03DC03
ATC
montelukast; oral
1.7
6.8
136
834
R02
ICPC
Shortness of breath/dyspnoea
1.8
6.8
113
658
7263A
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of elbow region[EPICONDYLITIS LATERALIS HUMERI]
9.4
6.8
13
14
G55.1*M51.9
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders (M50-M51+)
40.3
6.8
8
*
ACC19
NOMESCO Finland
Transcision of peripheral nerve: other or unspecified
40.3
6.8
8
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
6.8
218
1527
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
4.1
6.7
24
59
G56.9
ICD-10 Finland
Mononeuropathy of upper limb, unspecified
22.7
6.7
9
*
J01FA10
ATC
azithromycin; systemic
1.4
6.7
450
3674
A10BA02
ATC
metformin; oral
1.5
6.6
248
1792
TQW40
SPAT
NA
3.4
6.6
29
86
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
4.0
6.5
24
61
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
3.7
6.5
26
71
R42
ICD-10 Finland
Dizziness and giddiness
1.5
6.5
215
1513
6451
FHL
Dilatation
5.7
6.5
17
30
M67.4
ICD-10 Finland
Ganglion
2.4
6.5
53
232
TAB20
NOMESCO Finland
Epidural puncture
8.2
6.3
13
16
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
2.5
6.3
46
189
L14
ICPC
Leg/thigh symptom/complaint
2.1
6.3
71
358
M09AX01
ATC
hyaluronic acid; parenteral
2.2
6.3
59
274
S97
ICPC
Chronic ulcer skin
2.3
6.3
54
241
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
6.3
477
3965
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
6.3
244
1779
3548X
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Other mononeuritis of upper limb
+∞
6.3
6
*
S64.1
ICD-10 Finland
Injury of median nerve at wrist and hand level
+∞
6.3
6
*
G58.7
ICD-10 Finland
Mononeuritis multiplex
+∞
6.3
6
*
3543A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Lesion of radial nerve
+∞
6.3
6
*
M18.0
ICD-10 Finland
Primary arthrosis of first carpometacarpal joints, bilateral
4.8
6.2
19
40
J01FA06
ATC
roxithromycin; oral
1.4
6.2
345
2703
7270B
ICD-9 Finland
Other disorders of synovium, tendon and bursa, Synovitis and tenosynovitis[TENOSYNOVITIS CARPI ET ANTEBRACHII]
26.9
6.2
8
*
160
Kela drug reimbursment
exenatide
4.0
6.2
23
59
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
4.5
6.2
20
45
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.2
138
876
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.2
328
2548
R13
ICD-10 Finland
Dysphagia
2.2
6.2
60
282
M54.1
ICD-10 Finland
Radiculopathy
2.8
6.1
37
137
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
12.6
6.1
10
8
9481
FHL
Detachment or severance of a muscle or tendon
8.7
6.1
12
14
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.2
6.0
55
253
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.6
6.0
41
163
Mortality – FinRegistry
↥Association
Association between endpoint G6_MEDLEOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_MEDLEOTH | 0.892 [0.75, 1.07] | 0.212 |
| Birth year | 0.998 [0.99, 1.01] | 0.646 |
During the follow-up period (1.1.1998 — 31.12.2019), 141 out of 1512 females with G6_MEDLEOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_MEDLEOTH | 1.025 [0.82, 1.28] | 0.823 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 169 out of 1159 males with G6_MEDLEOTH died.
Mortality risk
Mortality risk for people of age
years, who have G6_MEDLEOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.081% | 0.187% |
| 5 | 0.625% | 1.053% |
| 10 | 1.59% | 2.713% |
| 15 | 2.958% | 4.969% |
| 20 | 5.052% | 8.629% |
Relationships between endpoints
↥Index endpoint: G6_MEDLEOTH – Other lesions of median nerve
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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